locus-tag	class	description
BRW62_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BRW62_00025	ENOG4105DX0	Hemolysin A
BRW62_00045	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
BRW62_00050	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
BRW62_00110	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
BRW62_00120	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BRW62_00130	ENOG4105EUJ	GTP cyclohydrolase i
BRW62_00135	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BRW62_00145	ENOG4105ETX	regulatoR
BRW62_00155	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BRW62_00160	ENOG4105C9X	ppx gppa phosphatase
BRW62_00165	ENOG4105CSR	polyphosphate kinase 2
BRW62_00175	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BRW62_00210	ENOG4105CDU	Replicative dna helicase
BRW62_00210	ENOG4105CDU	Replicative dna helicase
BRW62_00240	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BRW62_00250	ENOG4105DWY	Agmatine deiminase
BRW62_00255	ENOG41082HT	Binds the 23S rRNA (By similarity)
BRW62_00260	ENOG4108UJD	30S ribosomal protein S9
BRW62_00265	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BRW62_00270	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BRW62_00275	ENOG4108ZT0	50S ribosomal protein l17
BRW62_00280	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BRW62_00285	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BRW62_00290	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BRW62_00295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BRW62_00300	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BRW62_00305	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BRW62_00310	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BRW62_00315	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BRW62_00320	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BRW62_00325	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BRW62_00330	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BRW62_00335	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BRW62_00340	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BRW62_00345	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BRW62_00350	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BRW62_00355	ENOG410848H	50s ribosomal protein l29
BRW62_00360	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BRW62_00365	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BRW62_00370	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BRW62_00375	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BRW62_00380	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BRW62_00385	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BRW62_00390	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BRW62_00395	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BRW62_00400	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BRW62_00410	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BRW62_00415	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
BRW62_00440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_00445	ENOG4105C0P	Mg chelatase subunit ChlI
BRW62_00490	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
BRW62_00505	ENOG4105ERG	peptidase m48, ste24p
BRW62_00510	ENOG4105EWU	Squalene--hopene cyclase
BRW62_00515	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
BRW62_00535	ENOG4107S5T	Carbohydrate kinase
BRW62_00540	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BRW62_00545	ENOG4105C9Q	fumarate hydratase class II
BRW62_00555	ENOG4108TGR	phosphatase
BRW62_00560	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BRW62_00570	ENOG4105EMN	RNA polymerase sigma factor
BRW62_00590	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BRW62_00615	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
BRW62_00635	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BRW62_00650	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BRW62_00655	ENOG4105HFZ	Membrane
BRW62_00670	ENOG4105D7V	transposase
BRW62_00710	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BRW62_00740	ENOG4105CPK	Glycosyl transferase (Group 1
BRW62_00745	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
BRW62_00765	ENOG4105M3Z	response regulator
BRW62_00780	ENOG4105CBS	Chea signal transduction histidine kinase
BRW62_00790	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BRW62_00795	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BRW62_00815	ENOG4108Z6B	deaminase
BRW62_00835	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BRW62_00840	ENOG4108JQC	penicillin-binding protein 1A
BRW62_00855	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BRW62_00860	ENOG4105EHU	Circadian clock protein KaiC
BRW62_00865	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
BRW62_00880	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BRW62_00905	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
BRW62_00915	ENOG4106MP8	UPF0754 membrane protein
BRW62_00925	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BRW62_00930	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
BRW62_00935	ENOG4105DR5	peptidase
BRW62_00975	ENOG4108Z6B	deaminase
BRW62_00980	ENOG4106815	This protein is a component of the reaction center of photosystem II (By similarity)
BRW62_00985	ENOG4105CDY	transcriptional regulatory protein
BRW62_01035	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BRW62_01040	ENOG4105CFG	Acts as a chaperone (By similarity)
BRW62_01075	ENOG4105IJJ	transcriptional regulator, crp fnr family
BRW62_01080	ENOG4105C8Y	Acetylornithine aminotransferase
BRW62_01085	ENOG4107VC8	ATP cone domain protein
BRW62_01120	ENOG4105CN1	protease
BRW62_01215	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BRW62_01220	ENOG4105C8N	cysteinyl-tRNA synthetase
BRW62_01225	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BRW62_01230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BRW62_01245	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BRW62_01250	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BRW62_01280	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BRW62_01295	ENOG4108ZF3	Phosphatase
BRW62_01300	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
BRW62_01305	ENOG4105CZX	twitching motility protein
BRW62_01310	ENOG4105PW4	Sugar fermentation stimulation protein homolog
BRW62_01315	ENOG410828V	rubredoxin
BRW62_01320	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
BRW62_01325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_01360	ENOG4108VCT	Sulfite exporter TauE/SafE
BRW62_01405	ENOG4105WN5	stage II sporulation protein
BRW62_01445	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BRW62_01465	ENOG41080E3	single-stranded DNA-binding protein
BRW62_01470	ENOG4105BZU	Histidine kinase
BRW62_01490	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
BRW62_01505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BRW62_01515	ENOG41084W5	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BRW62_01520	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BRW62_01535	ENOG4105C8B	TIGR00159 family
BRW62_01540	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BRW62_01610	ENOG4105DCF	alanine dehydrogenase
BRW62_01615	ENOG4105CQC	Prephenate dehydratase
BRW62_01620	ENOG4105IDI	abc transporter atp-binding protein
BRW62_01625	ENOG4105F23	Fibronectin-binding protein
BRW62_01635	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BRW62_01645	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
BRW62_01680	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
BRW62_01720	ENOG4108VIA	integral membrane protein
BRW62_01735	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BRW62_01745	ENOG4108IUZ	ABC transporter
BRW62_01765	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BRW62_01775	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BRW62_01780	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BRW62_01795	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BRW62_01800	ENOG4105MSA	Photosystem II reaction center W protein
BRW62_01810	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BRW62_01835	ENOG4105CA3	membrane-bound lytic murein transglycosylase
BRW62_01840	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BRW62_01845	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BRW62_01855	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
BRW62_01860	ENOG4108Z61	cytochrome c-550
BRW62_01865	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
BRW62_01875	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BRW62_01880	ENOG4107YBY	Hydrolase
BRW62_01885	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BRW62_01890	ENOG4105W8H	transhydrogenase (subunit alpha
BRW62_01895	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BRW62_01940	ENOG4105D75	Capsular exopolysaccharide family
BRW62_01955	ENOG4105CPK	Glycosyl transferase (Group 1
BRW62_01960	ENOG4105CG5	Glycosyl transferase (Group 1
BRW62_01975	ENOG4107STW	synthase
BRW62_02010	ENOG4105CAQ	asparagine synthetase
BRW62_02035	ENOG4107YJ4	chain length determinant protein
BRW62_02040	ENOG4105CKI	cobalamin synthesis protein
BRW62_02045	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BRW62_02070	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
BRW62_02110	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BRW62_02145	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BRW62_02155	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BRW62_02160	ENOG4105C32	Amino acid ABC transporter (Permease)
BRW62_02170	ENOG4105CVB	Vitamin K epoxide reductase
BRW62_02185	ENOG4105BZU	Histidine kinase
BRW62_02195	ENOG4108IJ9	(ABC) transporter
BRW62_02215	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BRW62_02220	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BRW62_02230	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BRW62_02235	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BRW62_02245	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BRW62_02255	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BRW62_02270	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BRW62_02280	ENOG4105EYM	Major Facilitator superfamily
BRW62_02290	ENOG4105FFC	UPF0187 protein
BRW62_02305	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BRW62_02325	ENOG4105EB3	Histidine kinase
BRW62_02360	ENOG4107RNB	anthranilate phosphoribosyltransferase
BRW62_02370	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BRW62_02380	ENOG4105JFG	SpoIID LytB domain protein
BRW62_02395	ENOG4105DUM	transcriptional regulator, lysR family
BRW62_02425	ENOG4108VPT	UPF0234 protein
BRW62_02440	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BRW62_02460	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
BRW62_02465	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BRW62_02480	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BRW62_02485	ENOG4105BZU	Histidine kinase
BRW62_02495	ENOG4105DHP	deoxycytidine triphosphate deaminase
BRW62_02505	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BRW62_02520	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BRW62_02525	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BRW62_02535	ENOG4108JJB	ABC transporter
BRW62_02540	ENOG4105M3Z	response regulator
BRW62_02545	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BRW62_02550	ENOG4105EYH	Exonuclease
BRW62_02555	ENOG4105F8J	Adenylate Guanylate cyclase
BRW62_02590	ENOG4105CVN	desaturase
BRW62_02595	ENOG4107QHM	Sulfite reductase
BRW62_02605	ENOG4105IDI	abc transporter atp-binding protein
BRW62_02610	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BRW62_02625	ENOG4105EMN	RNA polymerase sigma factor
BRW62_02680	ENOG4105DA5	(ABC) transporter
BRW62_02685	ENOG4105F0R	Cytidylyltransferase
BRW62_02695	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BRW62_02705	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BRW62_02725	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BRW62_02735	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BRW62_02755	ENOG4105ZDH	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
BRW62_02765	ENOG4105CVB	Vitamin K epoxide reductase
BRW62_02770	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BRW62_02775	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
BRW62_02780	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BRW62_02795	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BRW62_02805	ENOG4105CFG	Acts as a chaperone (By similarity)
BRW62_02810	ENOG4105J0C	
BRW62_02820	ENOG4108FYC	transcriptional regulator MERR family
BRW62_02835	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BRW62_02850	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
BRW62_02855	ENOG4105C32	Amino acid ABC transporter (Permease)
BRW62_02860	ENOG4105C32	Amino acid ABC transporter (Permease)
BRW62_02865	ENOG4105C0Z	ABC transporter
BRW62_02880	ENOG4105C09	Bile acid
BRW62_02905	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BRW62_02910	ENOG4105DZP	Membrane-associated zinc metalloprotease
BRW62_02945	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BRW62_02965	ENOG4105C5F	glutamine synthetase
BRW62_02975	ENOG4105CXT	aspartate transcarbamylase
BRW62_03015	ENOG4105C59	p-type ATPase
BRW62_03045	ENOG4105D7V	transposase
BRW62_03050	ENOG4108S1Y	allophycocyanin alpha-B chain
BRW62_03055	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BRW62_03110	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BRW62_03115	ENOG4105K46	50S ribosomal protein l27
BRW62_03125	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BRW62_03135	ENOG4105BZF	Glycosyl transferase (Group 1
BRW62_03155	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BRW62_03170	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BRW62_03190	ENOG4105CT3	Monooxygenase
BRW62_03205	ENOG4105EMU	Dehydrogenase
BRW62_03225	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
BRW62_03245	ENOG4105DA5	(ABC) transporter
BRW62_03265	ENOG4107TVC	Glycosyl transferase, family 2
BRW62_03280	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BRW62_03295	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BRW62_03300	ENOG4107WZZ	SMC domain protein
BRW62_03330	ENOG4106H78	methyltransferase
BRW62_03335	ENOG41090A1	ferritin
BRW62_03360	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BRW62_03385	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BRW62_03395	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BRW62_03400	ENOG4105BZ1	(ABC) transporter
BRW62_03415	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BRW62_03430	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BRW62_03445	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BRW62_03460	ENOG4105CDH	Citrulline--aspartate ligase
BRW62_03465	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BRW62_03480	ENOG4107RRY	Cyanophycin synthetase
BRW62_03500	ENOG4105WN5	stage II sporulation protein
BRW62_03525	ENOG4105EVN	Prephenate dehydrogenase
BRW62_03545	ENOG4105C5I	Dehydrogenase
BRW62_03560	ENOG4105DBV	ornithine carbamoyltransferase
BRW62_03565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BRW62_03585	ENOG4105I3K	Ferric uptake regulator, Fur family
BRW62_03625	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BRW62_03635	ENOG4108ZJ4	polysaccharide deacetylase
BRW62_03640	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BRW62_03645	ENOG4105E2Z	phosphate ABC transporter (Permease
BRW62_03650	ENOG4105C8U	phosphate abc transporter
BRW62_03695	ENOG4105DFU	Cell wall formation (By similarity)
BRW62_03700	ENOG4105D4A	Cell wall formation (By similarity)
BRW62_03705	ENOG4107TVC	Glycosyl transferase, family 2
BRW62_03725	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BRW62_03750	ENOG4105E4G	Type IV pilus
BRW62_03760	ENOG4105D49	3-dehydroquinate synthase
BRW62_03770	ENOG4108NWW	ferritin dps family protein
BRW62_03775	ENOG4108Z4X	TRANSCRIPTIONal
BRW62_03780	ENOG4108062	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BRW62_03790	ENOG4105BZU	Histidine kinase
BRW62_03795	ENOG4107SC0	ferredoxin--NADP reductase
BRW62_03805	ENOG4105E4F	Isochorismate synthase
BRW62_03810	ENOG4105E0X	reductase
BRW62_03820	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BRW62_03835	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BRW62_03850	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BRW62_03855	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BRW62_03860	ENOG4105C7Z	Conserved Protein
BRW62_03865	ENOG4105KRF	dihydroneopterin aldolase
BRW62_03885	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
BRW62_03900	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BRW62_03905	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BRW62_03910	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BRW62_03915	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BRW62_03920	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BRW62_03930	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BRW62_03940	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BRW62_03970	ENOG4105KHC	sulfurtransferase
BRW62_03990	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BRW62_03995	ENOG4107SDZ	Galactoside transport system permease protein mglC
BRW62_04005	ENOG4105D0M	Protease HtpX homolog
BRW62_04010	ENOG4105F8J	Adenylate Guanylate cyclase
BRW62_04035	ENOG4105C26	Dehydrogenase
BRW62_04060	ENOG4107R7Y	intracellular protease Pfpi family
BRW62_04080	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BRW62_04090	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRW62_04095	ENOG4105KNY	Microcompartments protein
BRW62_04100	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
BRW62_04105	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BRW62_04110	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
BRW62_04115	ENOG4105MN7	Carbon dioxide concentrating mechanism protein
BRW62_04130	ENOG4105CBX	hi0933 family
BRW62_04145	ENOG4105D8X	mechanosensitive ion channel
BRW62_04175	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRW62_04180	ENOG4105DJZ	UPF0182 protein
BRW62_04185	ENOG4105CPT	Alpha beta hydrolase
BRW62_04200	ENOG4105VN1	Heat shock protein
BRW62_04225	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRW62_04245	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
BRW62_04250	ENOG4108XAD	Protein of unknown function (DUF1997)
BRW62_04255	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
BRW62_04285	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
BRW62_04295	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BRW62_04300	ENOG4107QPR	SAICAR synthetase
BRW62_04310	ENOG4107FQX	Alpha-acetolactate decarboxylase
BRW62_04320	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
BRW62_04330	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BRW62_04340	ENOG4108SIY	photosystem I reaction center protein subunit XI
BRW62_04350	ENOG4105CJN	penicillin-binding protein
BRW62_04355	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BRW62_04365	ENOG4108JJB	ABC transporter
BRW62_04370	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
BRW62_04375	ENOG410906A	Beta-Ig-H3 fasciclin
BRW62_04385	ENOG4107RFW	hydrolase family 57
BRW62_04420	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BRW62_04430	ENOG41080HI	glycine oxidase
BRW62_04445	ENOG4105DXN	mazG family
BRW62_04460	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BRW62_04470	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
BRW62_04475	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BRW62_04480	ENOG4105CE9	30S ribosomal protein S2
BRW62_04515	ENOG4105ETX	regulatoR
BRW62_04530	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BRW62_04535	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BRW62_04540	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BRW62_04545	ENOG4105CIK	Amidinotransferase
BRW62_04590	ENOG4107XWB	Zinc finger, swim domain protein
BRW62_04595	ENOG4108SHJ	s-layer protein
BRW62_04610	ENOG4105CPQ	Dehydrogenase
BRW62_04620	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BRW62_04625	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BRW62_04640	ENOG4105CEY	Amp-dependent synthetase and ligase
BRW62_04645	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BRW62_04655	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BRW62_04670	ENOG4105C8S	subunit m
BRW62_04675	ENOG4107XM9	(LipO)protein
BRW62_04685	ENOG4105CHM	Aminotransferase
BRW62_04690	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BRW62_04700	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
BRW62_04705	ENOG4107RH8	nuclease SbcCD subunit D
BRW62_04720	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BRW62_04765	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
BRW62_04795	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BRW62_04805	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
BRW62_04820	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
BRW62_04835	ENOG4105CEV	competence damage-inducible protein
BRW62_04840	ENOG4105ESV	Glycosyl transferase, family 4
BRW62_04845	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BRW62_04855	ENOG4108PJD	permease
BRW62_04860	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BRW62_04880	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BRW62_04885	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BRW62_04890	ENOG4105WIA	photosystem II reaction center protein H
BRW62_04895	ENOG410686T	photosystem II reaction center protein N
BRW62_04900	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
BRW62_04915	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
BRW62_04920	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BRW62_04925	ENOG4108UV1	cellular component movement
BRW62_04935	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BRW62_04940	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BRW62_04965	ENOG4107S6X	Glycosyl transferase, family 2
BRW62_04975	ENOG4105C7K	acetolactate synthase
BRW62_04980	ENOG4105KZX	Pterin carbinolamine dehydratase
BRW62_04990	ENOG41082B1	30S ribosomal protein S16
BRW62_04995	ENOG4105VB6	UPF0109 protein
BRW62_05000	ENOG4105VCC	30S ribosomal protein S21
BRW62_05020	ENOG4105C12	Phosphoribosylglycinamide synthetase
BRW62_05030	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BRW62_05040	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BRW62_05055	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BRW62_05060	ENOG4105D07	Signal peptide peptidase, SppA
BRW62_05070	ENOG4105DC8	reductase
BRW62_05075	ENOG4105CN1	protease
BRW62_05085	ENOG4105C7K	acetolactate synthase
BRW62_05090	ENOG4105JHY	Membrane
BRW62_05105	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BRW62_05115	ENOG4105C8M	UPF0272 protein
BRW62_05120	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BRW62_05125	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BRW62_05130	ENOG4107XMU	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BRW62_05175	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BRW62_05190	ENOG4108R99	pseudouridine synthase
BRW62_05200	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BRW62_05225	ENOG4105FA2	dna polymerase iii
BRW62_05230	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BRW62_05245	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BRW62_05260	ENOG4105DDQ	anthranilate synthase
BRW62_05265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_05270	ENOG4105D7V	transposase
BRW62_05280	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BRW62_05300	ENOG4105J0U	photosystem II
BRW62_05310	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BRW62_05320	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BRW62_05335	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BRW62_05345	ENOG4105CVR	type I restriction-modification system
BRW62_05365	ENOG4105EKX	Restriction modification system DNA (Specificity
BRW62_05405	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BRW62_05435	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
BRW62_05470	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BRW62_05475	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BRW62_05490	ENOG4105BZ1	(ABC) transporter
BRW62_05505	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BRW62_05520	ENOG4105D44	asparaginase
BRW62_05530	ENOG41060PQ	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BRW62_05550	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BRW62_05560	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BRW62_05565	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BRW62_05580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BRW62_05585	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
BRW62_05595	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BRW62_05600	ENOG4105BZ1	(ABC) transporter
BRW62_05605	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BRW62_05610	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
BRW62_05630	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BRW62_05635	ENOG4107RIQ	Sulfate adenylate transferase
BRW62_05645	ENOG4105D17	glycoside hydrolase, family 3 domain protein
BRW62_05670	ENOG41084A0	50s ribosomal protein L35
BRW62_05675	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BRW62_05680	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BRW62_05685	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
BRW62_05700	ENOG4108PWY	Carbohydrate-selective porin OprB
BRW62_05705	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BRW62_05725	ENOG4105CP7	Triose-phosphate isomerase
BRW62_05735	ENOG4107WCQ	Anion-transporting ATPase
BRW62_05765	ENOG4105CKK	Glycosyl transferase, family 2
BRW62_05775	ENOG4105CRE	cytochrome C
BRW62_05780	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BRW62_05805	ENOG4107Z6A	sulfate abc transporter permease
BRW62_05810	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BRW62_05830	ENOG4105D74	hydrolase
BRW62_05840	ENOG4105C3G	gtp-binding protein
BRW62_05845	ENOG4107QZB	decarboxylase
BRW62_05850	ENOG4105K70	DNA-binding protein
BRW62_05855	ENOG4105BZA	Phosphoglycerate kinase
BRW62_05930	ENOG4105K4H	Nlp p60 protein
BRW62_05935	ENOG4107QVP	Dehydrogenase
BRW62_05950	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BRW62_05985	ENOG4108R6K	riboflavin synthase, subunit alpha
BRW62_05995	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BRW62_06000	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BRW62_06020	ENOG4105K63	Thioredoxin
BRW62_06035	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BRW62_06040	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BRW62_06055	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BRW62_06060	ENOG4105I8F	Histidine kinase
BRW62_06080	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BRW62_06085	ENOG41083EU	50s ribosomal protein l28
BRW62_06090	ENOG4107SC1	transglycosylase
BRW62_06105	ENOG4105DKQ	ROK family
BRW62_06135	ENOG4108UW8	fha domain-containing protein
BRW62_06140	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
BRW62_06150	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
BRW62_06160	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BRW62_06165	ENOG4105FEU	K -dependent Na -Ca exchanger
BRW62_06170	ENOG4105D7V	transposase
BRW62_06180	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BRW62_06200	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BRW62_06210	ENOG4107U45	Cobalt transport protein
BRW62_06220	ENOG41080ZE	Adenylate cyclase
BRW62_06250	ENOG4105BZU	Histidine kinase
BRW62_06265	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BRW62_06290	ENOG4105C22	threonyL-tRNA synthetase
BRW62_06295	ENOG4105C22	threonyL-tRNA synthetase
BRW62_06305	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BRW62_06310	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BRW62_06330	ENOG4105CHH	sulfate transporter
BRW62_06335	ENOG4108VX5	3-methyladenine DNA glycosylase
BRW62_06385	ENOG4107QKW	extracellular solute-binding protein family 1
BRW62_06390	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BRW62_06395	ENOG4105CC5	ABC transporter
BRW62_06400	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BRW62_06405	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BRW62_06415	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BRW62_06420	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BRW62_06430	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BRW62_06435	ENOG4107RAQ	aminopeptidase
BRW62_06440	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BRW62_06450	ENOG4105EGS	Mechanosensitive ion channel
BRW62_06460	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BRW62_06465	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BRW62_06475	ENOG4105BZU	Histidine kinase
BRW62_06475	ENOG4105BZU	Histidine kinase
BRW62_06505	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BRW62_06510	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BRW62_06530	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BRW62_06560	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BRW62_06570	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BRW62_06575	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BRW62_06585	ENOG4106DN3	This protein is a component of the reaction center of photosystem II (By similarity)
BRW62_06595	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
BRW62_06600	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
BRW62_06625	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BRW62_06630	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
BRW62_06660	ENOG4108IQE	Amp-dependent synthetase and ligase
BRW62_06665	ENOG4108Z03	MAF-like protein
BRW62_06670	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BRW62_06685	ENOG4107QRP	cobalamin biosynthesis protein CobW
BRW62_06690	ENOG4105CQB	FAD linked oxidase domain protein
BRW62_06700	ENOG4105KNY	Microcompartments protein
BRW62_06720	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BRW62_06725	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BRW62_06730	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BRW62_06745	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BRW62_06750	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BRW62_06755	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BRW62_06770	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BRW62_06785	ENOG4105EU8	FAD linked oxidase domain protein
BRW62_06790	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BRW62_06795	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BRW62_06805	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BRW62_06805	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BRW62_06810	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BRW62_06815	ENOG41083MR	nifu domain-containing protein
BRW62_06825	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
BRW62_06830	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BRW62_06895	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
BRW62_06905	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BRW62_06915	ENOG4105VFU	Rna-binding protein
BRW62_06950	ENOG4105DVK	Precorrin-2 c20-methyltransferase
BRW62_06955	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BRW62_06960	ENOG4105WJF	
BRW62_06965	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BRW62_06990	ENOG4105DUM	transcriptional regulator, lysR family
BRW62_06995	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BRW62_07005	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BRW62_07020	ENOG4105D7V	transposase
BRW62_07025	ENOG4105JFG	SpoIID LytB domain protein
BRW62_07030	ENOG4108DIF	synthase (EC 4.2.1.75)
BRW62_07075	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BRW62_07080	ENOG4105WH1	Two component transcriptional regulator luxr family
BRW62_07085	ENOG4105IDI	abc transporter atp-binding protein
BRW62_07130	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BRW62_07135	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
BRW62_07155	ENOG4105CMR	udp-glucose 4-epimerase
BRW62_07165	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BRW62_07170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_07190	ENOG4107R1X	phosphohexokinase
BRW62_07200	ENOG4105CND	Glycosyl transferase, family 2
BRW62_07205	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
BRW62_07215	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BRW62_07230	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
BRW62_07245	ENOG4105ERH	Fumarylacetoacetate hydrolase
BRW62_07250	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
BRW62_07265	ENOG4108JYK	Dehydrogenase
BRW62_07275	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BRW62_07290	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BRW62_07300	ENOG4105XCI	PucC protein
BRW62_07305	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
BRW62_07330	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BRW62_07340	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BRW62_07355	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BRW62_07420	ENOG4105CAS	nag kinase
BRW62_07425	ENOG4107QZ7	Cellulose synthase catalytic subunit
BRW62_07435	ENOG4108UHU	Aldolase
BRW62_07450	ENOG4107QRA	Extracellular solute-binding protein, family 5
BRW62_07460	ENOG4105K63	Thioredoxin
BRW62_07465	ENOG410902C	phosphohistidine phosphatase, SixA
BRW62_07485	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BRW62_07495	ENOG4105CZX	twitching motility protein
BRW62_07500	ENOG4107QHF	type ii secretion system protein e
BRW62_07510	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
BRW62_07515	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BRW62_07525	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
BRW62_07540	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BRW62_07590	ENOG4108MXD	gtp-binding protein
BRW62_07615	ENOG4108YZ9	Urea amidohydrolase subunit gamma
BRW62_07640	ENOG4105CQM	Urea amidohydrolase subunit alpha
BRW62_07645	ENOG41083KH	UPF0102 protein
BRW62_07650	ENOG4105C3M	thioredoxin reductase
BRW62_07655	ENOG4105EJ9	Membrane
BRW62_07665	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BRW62_07700	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BRW62_07720	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BRW62_07725	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BRW62_07740	ENOG4107QI6	Cysteine desulfurase
BRW62_07750	ENOG4105C9M	aspartyl-trna synthetase
BRW62_07765	ENOG4105BZ1	(ABC) transporter
BRW62_07775	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BRW62_07780	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BRW62_07790	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BRW62_07795	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
BRW62_07810	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
BRW62_07820	ENOG4105C19	ABC transporter
BRW62_07830	ENOG4105F0I	Aminotransferase
BRW62_07840	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BRW62_07845	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BRW62_07895	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BRW62_07910	ENOG4105CHV	Transcription elongation factor NusA
BRW62_07915	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
BRW62_07935	ENOG4105CD2	stage iii sporulation protein aa
BRW62_07945	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BRW62_07965	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BRW62_07970	ENOG4105C8U	phosphate abc transporter
BRW62_07975	ENOG4105E2Z	phosphate ABC transporter (Permease
BRW62_07980	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BRW62_08010	ENOG4105D7V	transposase
BRW62_08020	ENOG4105BZ1	(ABC) transporter
BRW62_08065	ENOG4108PWY	Carbohydrate-selective porin OprB
BRW62_08085	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
BRW62_08125	ENOG4105CZN	Potassium uptake protein
BRW62_08140	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRW62_08155	ENOG4105EJG	cellulose synthase
BRW62_08160	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BRW62_08165	ENOG4108K7V	UPF0284 protein
BRW62_08185	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BRW62_08195	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
BRW62_08205	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BRW62_08235	ENOG4108S64	thioredoxin-like protein txlA
BRW62_08240	ENOG4105CTK	cobaltochelatase, cobn subunit
BRW62_08245	ENOG4105BZU	Histidine kinase
BRW62_08250	ENOG4105C8T	Leucyl-tRNA synthetase
BRW62_08255	ENOG4108UNF	response regulator
BRW62_08260	ENOG4105C8Q	Methyl-accepting chemotaxis
BRW62_08265	ENOG4108UNF	response regulator
BRW62_08270	ENOG4108V3W	Chemotaxis protein, CheW
BRW62_08275	ENOG4105C8Q	Methyl-accepting chemotaxis
BRW62_08280	ENOG4105CBS	Chea signal transduction histidine kinase
BRW62_08285	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BRW62_08290	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BRW62_08300	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
BRW62_08305	ENOG4105C30	Nad-dependent epimerase dehydratase
BRW62_08315	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BRW62_08325	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
BRW62_08340	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
BRW62_08370	ENOG4108IJ6	ABC transporter
BRW62_08375	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BRW62_08380	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BRW62_08460	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BRW62_08480	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BRW62_08500	ENOG4107VRP	DNA repair exonuclease
BRW62_08545	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BRW62_08550	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BRW62_08560	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BRW62_08570	ENOG4105C1V	Peptidase, M16
BRW62_08625	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BRW62_08650	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
BRW62_08655	ENOG4105BZU	Histidine kinase
BRW62_08660	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BRW62_08665	ENOG4107QJE	Chromosome Partitioning Protein
BRW62_08690	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BRW62_08695	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BRW62_08700	ENOG4105VFU	Rna-binding protein
BRW62_08705	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BRW62_08710	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BRW62_08715	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BRW62_08730	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BRW62_08755	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BRW62_08765	ENOG41086BQ	Protein CrcB homolog
BRW62_08770	ENOG4105WMR	Protein CrcB homolog
BRW62_08790	ENOG4108IJ9	(ABC) transporter
BRW62_08830	ENOG41085RW	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BRW62_08855	ENOG4107QZ7	Cellulose synthase catalytic subunit
BRW62_08880	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BRW62_08885	ENOG4105KC4	UPF0296 protein
BRW62_08890	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BRW62_08905	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BRW62_08920	ENOG4105IBP	Cyclic peptide transporter
BRW62_08945	ENOG4108R0D	protein with myosin-like
BRW62_08955	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BRW62_08975	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BRW62_09025	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BRW62_09040	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BRW62_09045	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
BRW62_09065	ENOG4105C5S	asparaginyl-tRNA synthetase
BRW62_09090	ENOG4107ZYR	domain protein
BRW62_09115	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BRW62_09120	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BRW62_09145	ENOG4105CH7	arginosuccinase
BRW62_09150	ENOG4105EWN	Heme oxygenase
BRW62_09210	ENOG4108IPT	Naphthoate synthase
BRW62_09220	ENOG4105BZU	Histidine kinase
BRW62_09225	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
BRW62_09235	ENOG4105DGW	oligopeptidase A
BRW62_09245	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BRW62_09255	ENOG4105BZ1	(ABC) transporter
BRW62_09280	ENOG4108MAQ	allophycocyanin alpha
BRW62_09285	ENOG4105FBM	allophycocyanin beta subunit
BRW62_09290	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
BRW62_09305	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BRW62_09315	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BRW62_09350	ENOG4105D7T	ABC transporter
BRW62_09360	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
BRW62_09380	ENOG4108IV0	ABC, transporter
BRW62_09385	ENOG4105D65	subunit l
BRW62_09390	ENOG4105C8S	subunit m
BRW62_09400	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BRW62_09405	ENOG4105CNW	domain protein
BRW62_09410	ENOG4105CNW	domain protein
BRW62_09415	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BRW62_09420	ENOG4105CAT	Cytidine monophosphate kinase
BRW62_09435	ENOG4108IJ6	ABC transporter
BRW62_09465	ENOG4105CTK	cobaltochelatase, cobn subunit
BRW62_09475	ENOG41086B8	CoB-CoM heterodisulfide reductase
BRW62_09490	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BRW62_09510	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
BRW62_09515	ENOG4108IYU	L-aspartate oxidase
BRW62_09520	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BRW62_09545	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
BRW62_09590	ENOG4105CJW	magnesium transporter
BRW62_09600	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BRW62_09605	ENOG4105D7Z	glutathione synthase
BRW62_09620	ENOG4105C8S	subunit m
BRW62_09655	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BRW62_09665	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BRW62_09670	ENOG4108IAJ	Nad-dependent epimerase dehydratase
BRW62_09675	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BRW62_09680	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BRW62_09685	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
BRW62_09690	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BRW62_09695	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BRW62_09715	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BRW62_09730	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
BRW62_09735	ENOG4105C59	p-type ATPase
BRW62_09745	ENOG4105K64	Glycosyl transferase, family 2
BRW62_09775	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BRW62_09780	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BRW62_09785	ENOG4105CD3	dihydroorotase
BRW62_09790	ENOG4108Z0R	Transferase
BRW62_09800	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BRW62_09805	ENOG4105BZU	Histidine kinase
BRW62_09810	ENOG41065W4	chlorophyll a b binding light harvesting protein
BRW62_09820	ENOG4105DHT	Metal Dependent Phosphohydrolase
BRW62_09825	ENOG4105D3R	alkyl hydroperoxide reductase
BRW62_09840	ENOG4105VUV	UPF0367 protein
BRW62_09845	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
BRW62_09865	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BRW62_09900	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BRW62_09910	ENOG4105DR5	peptidase
BRW62_09935	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BRW62_09940	ENOG4105D5K	Hemolysin activator protein
BRW62_09960	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BRW62_09970	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BRW62_09995	ENOG4105E66	phosphoriboisomerase A
BRW62_10000	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BRW62_10010	ENOG4107QRI	Phosphoketolase
BRW62_10020	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
BRW62_10040	ENOG4105D52	delta-aminolevulinic acid dehydratase
BRW62_10055	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BRW62_10075	ENOG4108JJB	ABC transporter
BRW62_10085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BRW62_10090	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BRW62_10115	ENOG4105W5Q	DNA repair protein (RadC
BRW62_10120	ENOG4108PWY	Carbohydrate-selective porin OprB
BRW62_10125	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BRW62_10130	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BRW62_10140	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
BRW62_10170	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
BRW62_10185	ENOG4108R6G	acetyltransferase
BRW62_10220	ENOG4105CNG	UPF0061 protein
BRW62_10230	ENOG4105C59	p-type ATPase
BRW62_10235	ENOG4105CVA	phosphate
BRW62_10240	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BRW62_10275	ENOG4105CJN	penicillin-binding protein
BRW62_10285	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BRW62_10300	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BRW62_10305	ENOG4107SWE	Methyltransferase
BRW62_10320	ENOG4105CHW	UPF0052 protein
BRW62_10335	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BRW62_10340	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BRW62_10365	ENOG4107QZ7	Cellulose synthase catalytic subunit
BRW62_10370	ENOG4105CPF	Cell wall formation (By similarity)
BRW62_10410	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BRW62_10415	ENOG4105CFG	Acts as a chaperone (By similarity)
BRW62_10425	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
BRW62_10470	ENOG4107WDG	serine threonine protein kinase
BRW62_10480	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BRW62_10485	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_10535	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BRW62_10540	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BRW62_10545	ENOG4105CE4	GlcNAc 6-P deacetylase
BRW62_10570	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
BRW62_10595	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BRW62_10615	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BRW62_10630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BRW62_10635	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
BRW62_10655	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BRW62_10660	ENOG4105D6V	phycocyanin beta subunit
BRW62_10665	ENOG4108SDR	phycocyanin, alpha subunit
BRW62_10670	ENOG4108MZQ	phycobilisome linker polypeptide
BRW62_10675	ENOG4106DMB	CpcD phycobilisome linker domain protein
BRW62_10680	ENOG41078GB	pbs lyase
BRW62_10685	ENOG4108V9J	phycocyanobilin lyase
BRW62_10690	ENOG4106BTU	phycobilisome rod-core linker polypeptide
BRW62_10695	ENOG4106BTU	phycobilisome rod-core linker polypeptide
BRW62_10700	ENOG4106Q05	Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes (By similarity)
BRW62_10725	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BRW62_10740	ENOG4105CNI	cell division protein FtsW
BRW62_10755	ENOG4108RCM	Nitroreductase
BRW62_10760	ENOG4108PWY	Carbohydrate-selective porin OprB
BRW62_10780	ENOG4105KI2	Urea amidohydrolase subunit beta
BRW62_10805	ENOG4108ZIT	Ferredoxin, 2FE-2S
BRW62_10835	ENOG4107SGM	protein serine threonine phosphatase
BRW62_10845	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
BRW62_10855	ENOG4105CPQ	Dehydrogenase
BRW62_10875	ENOG4105CAK	Cell division ATP-binding protein ftsE
BRW62_10895	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BRW62_10910	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BRW62_10925	ENOG4105DR5	peptidase
BRW62_10930	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BRW62_10935	ENOG4108UNF	response regulator
BRW62_10940	ENOG4105M3Z	response regulator
BRW62_10950	ENOG4105C8Q	Methyl-accepting chemotaxis
BRW62_10955	ENOG4105CBS	Chea signal transduction histidine kinase
BRW62_10970	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BRW62_11005	ENOG4105DRS	transport system, permease
BRW62_11035	ENOG4105BZU	Histidine kinase
BRW62_11065	ENOG4106FVC	RNA methyltransferase
BRW62_11080	ENOG4105C0Z	ABC transporter
BRW62_11095	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BRW62_11105	ENOG4105C8Q	Methyl-accepting chemotaxis
BRW62_11115	ENOG4105M3Z	response regulator
BRW62_11120	ENOG4108UNF	response regulator
BRW62_11140	ENOG4105YVZ	photosystem II
BRW62_11145	ENOG4105BZU	Histidine kinase
BRW62_11155	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BRW62_11160	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BRW62_11180	ENOG4105F0N	pyrophosphate phospho-hydrolase
BRW62_11185	ENOG4105CHM	Aminotransferase
BRW62_11195	ENOG4106DDF	Photosystem II reaction center protein M
BRW62_11200	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BRW62_11240	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BRW62_11245	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BRW62_11265	ENOG41067UF	
BRW62_11310	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BRW62_11315	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BRW62_11320	ENOG4107Z3D	50S ribosomal protein l10
BRW62_11325	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BRW62_11330	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BRW62_11335	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
BRW62_11340	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BRW62_11345	ENOG4107TS3	membrane protein, TerC
BRW62_11350	ENOG4105JKW	Valine--pyruvate aminotransferase
BRW62_11375	ENOG4105E4C	Lytic transglycosylase catalytic
BRW62_11385	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
BRW62_11390	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
BRW62_11395	ENOG4107YZX	Universal stress protein
BRW62_11420	ENOG4108FN7	Aldo keto reductase
BRW62_11440	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
BRW62_11460	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
BRW62_11485	ENOG4108JQ6	ABC transporter
BRW62_11500	ENOG4107TVC	Glycosyl transferase, family 2
BRW62_11515	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BRW62_11520	ENOG4105EEK	Polypeptide
BRW62_11530	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BRW62_11550	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BRW62_11620	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BRW62_11660	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BRW62_11700	ENOG4105C0D	helicase
BRW62_11710	ENOG4105CXN	decarboxylase
BRW62_11775	ENOG4108VAU	general secretion pathway protein G
BRW62_11785	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BRW62_11790	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BRW62_11810	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BRW62_11815	ENOG4105CD5	CoA-binding domain protein
BRW62_11845	ENOG4105C01	Dihydroxy-acid dehydratase
BRW62_11865	ENOG4105C31	Tryptophanyl-tRNA synthetase
BRW62_11890	ENOG4105F1A	Pyruvate formate-lyase
BRW62_11895	ENOG4108EKI	Dehydrogenase
BRW62_11905	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BRW62_11910	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BRW62_11930	ENOG4105C0Z	ABC transporter
BRW62_11950	ENOG4105VF7	tolerance protein
BRW62_11980	ENOG4108IV0	ABC, transporter
BRW62_11985	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
BRW62_12000	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_12030	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
BRW62_12070	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BRW62_12095	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BRW62_12105	ENOG41067HS	methyltransferase
BRW62_12110	ENOG4105EAD	ABC transporter
BRW62_12115	ENOG4106PMH	Extracellular solute-binding protein family 3
BRW62_12120	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BRW62_12125	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BRW62_12150	ENOG4105BZU	Histidine kinase
BRW62_12190	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BRW62_12195	ENOG4105MKQ	Monovalent cation H antiporter subunit C
BRW62_12200	ENOG4105C8S	subunit m
BRW62_12215	ENOG4105CUT	histidyl-tRNA synthetase
BRW62_12235	ENOG4107YCR	Transcriptional regulator, ARSR family
BRW62_12250	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BRW62_12260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BRW62_12265	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
BRW62_12275	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BRW62_12320	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BRW62_12350	ENOG4105E2K	Glycosyl transferase (Group 1
BRW62_12410	ENOG4108N5B	2-phosphosulfolactate phosphatase
BRW62_12420	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BRW62_12425	ENOG4105BZ1	(ABC) transporter
BRW62_12445	ENOG4105BZU	Histidine kinase
BRW62_12500	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BRW62_12515	ENOG4105C7N	Xanthine uracil vitamin C permease
BRW62_12545	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BRW62_12560	ENOG4107RIX	inner membrane protein translocase component YidC