locus-tag	class	description
MY494_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MY494_00015	COG2154	pterin-4-alpha-carbinolamine dehydratase
MY494_00025	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_00030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MY494_00040	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MY494_00070	COG4451	ribulose bisphosphate carboxylase, small
MY494_00075	COG1850	ribulose-bisphosphate carboxylase activity
MY494_00080	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MY494_00095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MY494_00100	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MY494_00115	COG0531	amino acid
MY494_00120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MY494_00125	COG0659	secondary active sulfate transmembrane transporter activity
MY494_00150	COG0004	ammonium transporteR
MY494_00160	COG1959	2 iron, 2 sulfur cluster binding
MY494_00165	COG0471	metal ion transport
MY494_00165	COG3273	potassium ion transport
MY494_00175	COG1253	flavin adenine dinucleotide binding
MY494_00180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MY494_00185	COG0569	domain protein
MY494_00190	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MY494_00195	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MY494_00200	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MY494_00240	COG0730	response to heat
MY494_00245	COG0095	Lipoate-protein ligase
MY494_00250	COG0517	IMP dehydrogenase activity
MY494_00250	COG1994	Peptidase M50
MY494_00255	COG0135	phosphoribosylanthranilate isomerase activity
MY494_00265	COG0302	gtp cyclohydrolase
MY494_00270	COG4221	oxidoreductase activity
MY494_00280	COG5322	oxidoreductase activity
MY494_00285	COG3396	Phenylacetate-CoA oxygenase
MY494_00295	COG0539	negative regulation of cytoplasmic translation
MY494_00305	COG1496	oxidoreductase activity
MY494_00310	COG0415	Belongs to the DNA photolyase family
MY494_00320	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MY494_00345	COG0028	Belongs to the TPP enzyme family
MY494_00350	COG0739	heme binding
MY494_00350	COG0741	lytic transglycosylase activity
MY494_00350	COG1196	nuclear chromosome segregation
MY494_00355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_00375	COG0528	UMP kinase activity
MY494_00380	COG0233	cytoplasmic translational termination
MY494_00385	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
MY494_00395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MY494_00400	COG0768	penicillin binding
MY494_00420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MY494_00425	COG0681	Belongs to the peptidase S26 family
MY494_00450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MY494_00460	COG0442	prolyl-tRNA aminoacylation
MY494_00475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MY494_00480	COG1324	tolerance protein
MY494_00490	COG0629	single-stranded DNA binding
MY494_00505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MY494_00515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MY494_00520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_00525	COG1215	transferase activity, transferring glycosyl groups
MY494_00530	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MY494_00545	COG0181	hydroxymethylbilane synthase activity
MY494_00560	COG1611	Belongs to the LOG family
MY494_00610	COG1132	(ABC) transporter
MY494_00645	COG2154	pterin-4-alpha-carbinolamine dehydratase
MY494_00650	COG0367	asparagine synthase
MY494_00655	COG0542	response to heat
MY494_00675	COG2010	Cytochrome c
MY494_00685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MY494_00690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MY494_00730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MY494_00765	COG0339	signal peptide processing
MY494_00770	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_00775	COG0083	homoserine kinase activity
MY494_00780	COG0837	glucose binding
MY494_00785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MY494_00800	COG0180	Tryptophanyl-tRNA synthetase
MY494_00815	COG1230	cation diffusion facilitator family transporter
MY494_00840	COG1799	cell septum assembly
MY494_00845	COG0428	transporter
MY494_00860	COG0681	Belongs to the peptidase S26 family
MY494_00865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MY494_00870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MY494_00875	COG1376	ErfK ybiS ycfS ynhG family protein
MY494_00880	COG0297	glycogen (starch) synthase activity
MY494_00890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MY494_00895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MY494_00900	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MY494_00900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MY494_00905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MY494_00915	COG1959	2 iron, 2 sulfur cluster binding
MY494_00920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MY494_00925	COG2045	Belongs to the ComB family
MY494_00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
MY494_00940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MY494_00945	COG0142	geranyltranstransferase activity
MY494_00950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MY494_00955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MY494_00965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MY494_01000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY494_01010	COG1132	(ABC) transporter
MY494_01020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MY494_01025	COG0505	Belongs to the CarA family
MY494_01035	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MY494_01040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY494_01050	COG0154	amidase activity
MY494_01055	COG0587	DNA-directed DNA polymerase activity
MY494_01065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MY494_01070	COG0632	four-way junction helicase activity
MY494_01085	COG0358	DNA primase activity
MY494_01100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MY494_01120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MY494_01125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MY494_01135	COG0022	dehydrogenase e1 component
MY494_01140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MY494_01145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MY494_01160	COG0628	permease
MY494_01165	COG3310	Protein conserved in bacteria
MY494_01170	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MY494_01175	COG0515	serine threonine protein kinase
MY494_01200	COG2226	methyltransferase
MY494_01210	COG0174	glutamine synthetase
MY494_01220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MY494_01235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MY494_01240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MY494_01260	COG0612	Peptidase, M16
MY494_01280	COG1136	(ABC) transporter
MY494_01290	COG1216	Glycosyl transferase, family 2
MY494_01295	COG0052	Belongs to the universal ribosomal protein uS2 family
MY494_01300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MY494_01310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MY494_01315	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MY494_01320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY494_01325	COG0751	glycine-tRNA ligase activity
MY494_01335	COG0644	oxidoreductase
MY494_01345	COG0826	peptidase U32
MY494_01350	COG1217	gtp-binding protein TYPA
MY494_01365	COG1137	ATPase activity
MY494_01375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MY494_01380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MY494_01385	COG1494	fructose-1,6-bisphosphatase
MY494_01390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MY494_01395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MY494_01400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MY494_01405	COG0363	glucosamine-6-phosphate deaminase activity
MY494_01420	COG0129	dihydroxy-acid dehydratase activity
MY494_01430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MY494_01435	COG1357	PFAM Pentapeptide repeats (8 copies)
MY494_01455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MY494_01460	COG0047	phosphoribosylformylglycinamidine synthase activity
MY494_01465	COG1619	proteins homologs of microcin C7 resistance protein MccF
MY494_01470	COG0450	alkyl hydroperoxide reductase
MY494_01480	COG0745	RESPONSE REGULATOR receiver
MY494_01490	COG0572	uridine kinase
MY494_01505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MY494_01540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY494_01550	COG0557	exoribonuclease II activity
MY494_01555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MY494_01560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MY494_01565	COG0072	phenylalanine-tRNA ligase activity
MY494_01570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MY494_01605	COG0384	phenazine biosynthesis protein PhzF
MY494_01610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MY494_01630	COG1410	methionine synthase
MY494_01630	COG0646	methionine synthase
MY494_01635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MY494_01655	COG1981	membrane
MY494_01660	COG3046	protein related to deoxyribodipyrimidine photolyase
MY494_01670	COG0322	excinuclease ABC activity
MY494_01675	COG0426	domain, Protein
MY494_01675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MY494_01680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MY494_01705	COG1104	cysteine desulfurase activity
MY494_01710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MY494_01720	COG0495	leucyl-tRNA aminoacylation
MY494_01725	COG0166	Belongs to the GPI family
MY494_01750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MY494_01755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MY494_01760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MY494_01760	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MY494_01765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY494_01770	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MY494_01775	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MY494_01785	COG0484	heat shock protein binding
MY494_01790	COG0443	Heat shock 70 kDa protein
MY494_01795	COG0573	inorganic phosphate transmembrane transporter activity
MY494_01800	COG0581	inorganic phosphate transmembrane transporter activity
MY494_01805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MY494_01815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY494_01820	COG0483	inositol monophosphate 1-phosphatase activity
MY494_01825	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MY494_01850	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MY494_01855	COG1653	transport
MY494_01870	COG3842	ATPase activity
MY494_01890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MY494_01900	COG0668	transmembrane transport
MY494_01905	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MY494_01940	COG0784	Response regulator, receiver
MY494_01940	COG4191	Histidine kinase
MY494_01945	COG1122	ATPase activity
MY494_01955	COG1051	belongs to the nudix hydrolase family
MY494_02025	COG0284	orotidine-5'-phosphate decarboxylase activity
MY494_02025	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MY494_02035	COG1131	(ABC) transporter
MY494_02070	COG2226	methyltransferase
MY494_02120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MY494_02125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MY494_02150	COG0469	pyruvate kinase activity
MY494_02155	COG1136	(ABC) transporter
MY494_02155	COG0577	efflux transmembrane transporter activity
MY494_02165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY494_02175	COG0740	serine-type endopeptidase activity
MY494_02190	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MY494_02205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MY494_02275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MY494_02280	COG1175	transmembrane transport
MY494_02285	COG0514	ATP-dependent DNA helicase (RecQ)
MY494_02290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MY494_02325	COG3588	fructose-bisphosphate aldolase
MY494_02335	COG1793	dna ligase
MY494_02340	COG1201	RNA secondary structure unwinding
MY494_02385	COG0625	glutathione transferase activity
MY494_02400	COG0516	GMP reductase activity
MY494_02400	COG0517	IMP dehydrogenase activity
MY494_02425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MY494_02435	COG2197	response regulator
MY494_02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY494_02445	COG0114	fumarate hydratase activity
MY494_02450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MY494_02465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MY494_02480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MY494_02485	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY494_02490	COG0473	3-isopropylmalate dehydrogenase activity
MY494_02495	COG3954	Phosphoribulokinase
MY494_02505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MY494_02510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MY494_02520	COG0673	inositol 2-dehydrogenase activity
MY494_02525	COG0191	fructose-bisphosphate aldolase activity
MY494_02535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MY494_02540	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MY494_02550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY494_02555	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MY494_02565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MY494_02570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MY494_02570	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MY494_02585	COG2119	membrane
MY494_02595	COG0557	exoribonuclease II activity
MY494_02600	COG0163	prenyltransferase activity
MY494_02615	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MY494_02620	COG0312	modulator of DNA gyrase
MY494_02630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MY494_02640	COG0513	Belongs to the DEAD box helicase family
MY494_02655	COG0861	Integral membrane protein TerC family
MY494_02670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MY494_02680	COG0793	Belongs to the peptidase S41A family
MY494_02685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MY494_02690	COG1573	uracil-dna glycosylase
MY494_02700	COG0436	Aminotransferase
MY494_02705	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MY494_02715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MY494_02720	COG3639	organic phosphonate transmembrane transporter activity
MY494_02730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_02735	COG1836	PFAM Integral membrane protein DUF92
MY494_02755	COG1122	ATPase activity
MY494_02760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MY494_02780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MY494_02785	COG4106	trans-aconitate 2-methyltransferase activity
MY494_02900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MY494_02905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_02920	COG1429	ligase activity, forming nitrogen-metal bonds
MY494_03000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY494_03005	COG1132	(ABC) transporter
MY494_03010	COG2274	protein secretion by the type I secretion system
MY494_03020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MY494_03025	COG0149	triose-phosphate isomerase activity
MY494_03035	COG3706	GGDEF domain
MY494_03045	COG5001	Diguanylate cyclase
MY494_03045	COG3300	MHYT domain
MY494_03050	COG1132	(ABC) transporter
MY494_03065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MY494_03075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MY494_03110	COG2217	Heavy metal translocating P-type atpase
MY494_03130	COG1741	Belongs to the pirin family
MY494_03145	COG1773	rubredoxin
MY494_03155	COG3659	wide pore channel activity
MY494_03175	COG0745	RESPONSE REGULATOR receiver
MY494_03180	COG5002	protein histidine kinase activity
MY494_03185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY494_03195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MY494_03210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MY494_03215	COG0581	inorganic phosphate transmembrane transporter activity
MY494_03220	COG0573	inorganic phosphate transmembrane transporter activity
MY494_03230	COG0640	Transcriptional regulator
MY494_03235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MY494_03270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY494_03280	COG0709	Synthesizes selenophosphate from selenide and ATP
MY494_03285	COG2271	Major facilitator Superfamily
MY494_03290	COG1126	abc transporter atp-binding protein
MY494_03295	COG0765	amino acid transport
MY494_03300	COG4597	amino acid ABC transporter
MY494_03305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY494_03315	COG0418	dihydroorotase activity
MY494_03395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MY494_03400	COG0300	oxidoreductase activity
MY494_03405	COG1115	amino acid carrier protein
MY494_03415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MY494_03425	COG0799	negative regulation of ribosome biogenesis
MY494_03470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_03475	COG1301	dicarboxylic acid transport
MY494_03485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MY494_03490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_03505	COG3706	GGDEF domain
MY494_03525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_03540	COG2197	response regulator
MY494_03545	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MY494_03555	COG1877	trehalose-phosphatase activity
MY494_03600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MY494_03600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MY494_03600	COG1013	pyruvate-flavodoxin oxidoreductase activity
MY494_03600	COG0674	pyruvate-flavodoxin oxidoreductase activity
MY494_03610	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MY494_03615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MY494_03620	COG0375	protein maturation
MY494_03630	COG3259	Nickel-dependent hydrogenase
MY494_03635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_03640	COG1034	ATP synthesis coupled electron transport
MY494_03655	COG0574	Belongs to the PEP-utilizing enzyme family
MY494_03655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MY494_03675	COG2124	cytochrome p450
MY494_03775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_03780	COG2197	response regulator
MY494_03835	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MY494_03880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MY494_03885	COG0271	Belongs to the BolA IbaG family
MY494_03900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MY494_03925	COG1074	ATP-dependent DNA helicase activity
MY494_03940	COG0513	Belongs to the DEAD box helicase family
MY494_03950	COG0724	RNA recognition motif
MY494_03955	COG1132	(ABC) transporter
MY494_03960	COG1316	TRANSCRIPTIONal
MY494_03995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MY494_04015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MY494_04020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MY494_04045	COG1054	Belongs to the UPF0176 family
MY494_04050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MY494_04055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MY494_04060	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MY494_04065	COG0019	diaminopimelate decarboxylase activity
MY494_04070	COG0456	acetyltransferase
MY494_04075	COG0542	response to heat
MY494_04130	COG0371	Dehydrogenase
MY494_04145	COG0575	Belongs to the CDS family
MY494_04150	COG2242	protein methyltransferase activity
MY494_04150	COG2241	protein methyltransferase activity
MY494_04155	COG1982	Orn Lys Arg decarboxylase major
MY494_04160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MY494_04170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_04175	COG1187	pseudouridine synthase activity
MY494_04190	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
MY494_04205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MY494_04215	COG0308	aminopeptidase N
MY494_04230	COG2205	protein histidine kinase activity
MY494_04245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MY494_04250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MY494_04255	COG3429	Glucose-6-phosphate dehydrogenase subunit
MY494_04255	COG3409	Peptidoglycan-binding domain 1 protein
MY494_04260	COG1797	cobyrinic acid a,c-diamide synthase activity
MY494_04265	COG0406	alpha-ribazole phosphatase activity
MY494_04270	COG1254	Belongs to the acylphosphatase family
MY494_04290	COG0142	geranyltranstransferase activity
MY494_04300	COG1480	7TM receptor with intracellular HD hydrolase
MY494_04310	COG0564	pseudouridine synthase activity
MY494_04325	COG1799	cell septum assembly
MY494_04360	COG0436	Aminotransferase
MY494_04365	COG0395	ABC-type sugar transport system, permease component
MY494_04370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MY494_04380	COG1543	Belongs to the glycosyl hydrolase 57 family
MY494_04390	COG0644	oxidoreductase
MY494_04395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MY494_04410	COG0516	GMP reductase activity
MY494_04415	COG3118	belongs to the thioredoxin family
MY494_04420	COG1611	Belongs to the LOG family
MY494_04425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MY494_04430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MY494_04430	COG0116	Belongs to the methyltransferase superfamily
MY494_04440	COG2010	Cytochrome c
MY494_04445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MY494_04460	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MY494_04465	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MY494_04485	COG2166	iron-sulfur cluster assembly
MY494_04490	COG0460	homoserine dehydrogenase
MY494_04505	COG0601	transmembrane transport
MY494_04575	COG0012	GTP binding
MY494_04585	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MY494_04595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_04600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MY494_04615	COG0194	GDP metabolic process
MY494_04620	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MY494_04625	COG0805	protein transport
MY494_04635	COG0723	plastoquinol--plastocyanin reductase activity
MY494_04640	COG0739	heme binding
MY494_04670	COG0248	Ppx GppA phosphatase
MY494_04675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MY494_04680	COG1619	proteins homologs of microcin C7 resistance protein MccF
MY494_04685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MY494_04695	COG0569	domain protein
MY494_04700	COG1028	Short-chain dehydrogenase reductase Sdr
MY494_04710	COG0459	protein refolding
MY494_04720	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MY494_04740	COG0109	protoheme IX farnesyltransferase activity
MY494_04745	COG1612	heme a metabolic process
MY494_04755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MY494_04760	COG1845	cytochrome c oxidase, subunit III
MY494_04795	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MY494_04810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MY494_04815	COG1007	ATP synthesis coupled electron transport
MY494_04820	COG0577	efflux transmembrane transporter activity
MY494_04820	COG1136	(ABC) transporter
MY494_04825	COG0739	heme binding
MY494_04840	COG3118	belongs to the thioredoxin family
MY494_04845	COG1842	Phage shock protein A
MY494_04860	COG0438	transferase activity, transferring glycosyl groups
MY494_04865	COG0697	spore germination
MY494_04870	COG0616	signal peptide processing
MY494_04885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MY494_04890	COG0594	ribonuclease P activity
MY494_04900	COG0706	membrane insertase activity
MY494_04910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY494_04955	COG1104	cysteine desulfurase activity
MY494_04960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MY494_04970	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MY494_04975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MY494_04980	COG0134	indole-3-glycerol-phosphate synthase activity
MY494_04985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MY494_04990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY494_05005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MY494_05010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY494_05015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY494_05020	COG0285	dihydrofolate synthase activity
MY494_05055	COG4948	Mandelate Racemase Muconate Lactonizing
MY494_05060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY494_05065	COG1181	Belongs to the D-alanine--D-alanine ligase family
MY494_05080	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MY494_05095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MY494_05100	COG4956	integral membrane protein (PIN domain superfamily)
MY494_05105	COG0740	serine-type endopeptidase activity
MY494_05110	COG0740	serine-type endopeptidase activity
MY494_05115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MY494_05120	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MY494_05125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MY494_05130	COG0438	transferase activity, transferring glycosyl groups
MY494_05145	COG0556	nucleotide-excision repair
MY494_05195	COG2333	competence protein COMEC
MY494_05195	COG0658	competence protein
MY494_05200	COG0752	glycyl-tRNA synthetase alpha subunit
MY494_05215	COG3659	wide pore channel activity
MY494_05220	COG2226	methyltransferase
MY494_05230	COG0107	imidazoleglycerol-phosphate synthase activity
MY494_05240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MY494_05245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MY494_05250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MY494_05250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MY494_05255	COG3695	enzyme binding
MY494_05260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY494_05280	COG0745	RESPONSE REGULATOR receiver
MY494_05290	COG5002	protein histidine kinase activity
MY494_05350	COG0481	GTPase activity
MY494_05355	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MY494_05360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MY494_05365	COG0579	oxidoreductase
MY494_05370	COG0750	zinc metalloprotease
MY494_05375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MY494_05380	COG1185	polyribonucleotide nucleotidyltransferase activity
MY494_05390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MY494_05420	COG0484	heat shock protein binding
MY494_05425	COG4243	Vitamin k epoxide reductase
MY494_05485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MY494_05530	COG0116	Belongs to the methyltransferase superfamily
MY494_05535	COG3263	regulation of cellular component size
MY494_05550	COG1196	nuclear chromosome segregation
MY494_05560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY494_05575	COG0439	Biotin carboxylase
MY494_05590	COG0515	serine threonine protein kinase
MY494_05610	COG4178	(ABC) transporter
MY494_05615	COG0537	adenosine 5'-monophosphoramidase activity
MY494_05630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MY494_05645	COG0242	peptide deformylase activity
MY494_05650	COG1073	alpha beta
MY494_05665	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MY494_05675	COG2226	methyltransferase
MY494_05680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MY494_05685	COG0719	Fe-S assembly protein
MY494_05690	COG0396	ATPase activity
MY494_05695	COG0719	Fe-S assembly protein
MY494_05700	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
MY494_05725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MY494_05740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MY494_05765	COG0033	Phosphoglucomutase
MY494_05780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MY494_05795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MY494_05800	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MY494_05805	COG0175	sulfate reduction
MY494_05810	COG1252	NADH dehydrogenase
MY494_05820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MY494_05825	COG0450	alkyl hydroperoxide reductase
MY494_05830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MY494_05840	COG0488	(ABC) transporter
MY494_05850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MY494_05865	COG1643	Atp-dependent helicase
MY494_05880	COG1570	exodeoxyribonuclease VII activity
MY494_05935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MY494_05940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MY494_05945	COG0793	Belongs to the peptidase S41A family
MY494_05950	COG1078	dGTPase activity
MY494_05955	COG0850	regulation of cytokinetic process
MY494_05960	COG2059	Chromate
MY494_05975	COG2894	cell division
MY494_05980	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MY494_06025	COG0463	Glycosyl transferase, family 2
MY494_06030	COG5505	Protein of unknown function (DUF819)
MY494_06050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MY494_06060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MY494_06065	COG0254	rRNA binding
MY494_06070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MY494_06075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MY494_06080	COG0101	tRNA pseudouridine synthase activity
MY494_06085	COG0203	ribosomal protein L17
MY494_06090	COG0202	RNA polymerase activity
MY494_06095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MY494_06100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MY494_06105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MY494_06110	COG0563	adenylate kinase activity
MY494_06115	COG0201	protein transport
MY494_06120	COG0200	Binds to the 23S rRNA
MY494_06125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MY494_06130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MY494_06135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MY494_06145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MY494_06150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MY494_06155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MY494_06160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MY494_06165	COG0255	Belongs to the universal ribosomal protein uL29 family
MY494_06170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MY494_06175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MY494_06180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MY494_06185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MY494_06190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MY494_06195	COG0089	rRNA binding
MY494_06200	COG0088	Forms part of the polypeptide exit tunnel
MY494_06205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MY494_06220	COG3854	ATPases associated with a variety of cellular activities
MY494_06260	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
MY494_06265	COG3001	Fructosamine kinase
MY494_06285	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MY494_06290	COG1606	tRNA processing
MY494_06300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MY494_06305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MY494_06320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MY494_06325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MY494_06330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MY494_06345	COG0772	Belongs to the SEDS family
MY494_06350	COG0489	protein tyrosine kinase activity
MY494_06355	COG0408	coproporphyrinogen oxidase activity
MY494_06375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MY494_06445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MY494_06450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MY494_06455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MY494_06455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MY494_06460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MY494_06465	COG1413	lyase activity
MY494_06485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_06580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MY494_06620	COG1070	Carbohydrate kinase
MY494_06625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MY494_06630	COG0546	phosphoglycolate phosphatase activity
MY494_06635	COG0539	negative regulation of cytoplasmic translation
MY494_06640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MY494_06665	COG0589	response to stress
MY494_06670	COG0824	Thioesterase
MY494_06675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MY494_06675	COG0758	DNA mediated transformation
MY494_06680	COG2890	protein-(glutamine-N5) methyltransferase activity
MY494_06685	COG0009	L-threonylcarbamoyladenylate synthase
MY494_06695	COG2885	chlorophyll binding
MY494_06700	COG2885	chlorophyll binding
MY494_06720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MY494_06730	COG0067	glutamate synthase
MY494_06730	COG0069	glutamate synthase activity
MY494_06730	COG0070	glutamate synthase
MY494_06745	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MY494_06750	COG0049	tRNA binding
MY494_06760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MY494_06765	COG0051	transcription antitermination factor activity, RNA binding
MY494_06775	COG2226	methyltransferase
MY494_06780	COG0077	Prephenate dehydratase
MY494_06780	COG1605	Chorismate mutase
MY494_06790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MY494_06795	COG1530	ribonuclease E activity
MY494_06805	COG0436	Aminotransferase
MY494_06810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MY494_06825	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MY494_06835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MY494_06840	COG3386	PFAM SMP-30 Gluconolaconase
MY494_06845	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MY494_06860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY494_06865	COG0529	Catalyzes the synthesis of activated sulfate
MY494_06865	COG2046	Belongs to the sulfate adenylyltransferase family
MY494_06880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MY494_06885	COG3536	Protein conserved in bacteria
MY494_06910	COG0540	Belongs to the ATCase OTCase family
MY494_06915	COG2094	Belongs to the DNA glycosylase MPG family
MY494_06935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MY494_06955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MY494_06975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MY494_06990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MY494_06995	COG0739	heme binding
MY494_06995	COG1196	nuclear chromosome segregation
MY494_06995	COG0741	lytic transglycosylase activity
MY494_07010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY494_07020	COG0717	Belongs to the dCTP deaminase family
MY494_07030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MY494_07035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY494_07040	COG4372	Transposase
MY494_07045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MY494_07055	COG0193	aminoacyl-tRNA hydrolase activity
MY494_07060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MY494_07095	COG0066	3-isopropylmalate dehydratase activity
MY494_07100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MY494_07105	COG1058	Belongs to the CinA family
MY494_07105	COG1546	Belongs to the CinA family
MY494_07110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MY494_07115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MY494_07140	COG0728	peptidoglycan biosynthetic process
MY494_07145	COG1489	DNA binding
MY494_07150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MY494_07165	COG0138	bifunctional purine biosynthesis protein purh
MY494_07190	COG0343	queuine tRNA-ribosyltransferase activity
MY494_07210	COG0673	inositol 2-dehydrogenase activity
MY494_07215	COG1253	flavin adenine dinucleotide binding
MY494_07230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MY494_07235	COG0354	folic acid binding
MY494_07245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MY494_07250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MY494_07265	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MY494_07270	COG0131	Imidazoleglycerol-phosphate dehydratase
MY494_07275	COG3781	membrane
MY494_07280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MY494_07285	COG0415	Belongs to the DNA photolyase family
MY494_07355	COG1216	Glycosyl transferase, family 2
MY494_07355	COG0438	transferase activity, transferring glycosyl groups
MY494_07405	COG1083	cytidylyl-transferase
MY494_07410	COG1215	transferase activity, transferring glycosyl groups
MY494_07420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MY494_07435	COG0517	IMP dehydrogenase activity
MY494_07435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MY494_07445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MY494_07460	COG0415	Belongs to the DNA photolyase family
MY494_07465	COG0494	nUDIX hydrolase
MY494_07485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MY494_07490	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MY494_07490	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MY494_07500	COG3842	ATPase activity
MY494_07505	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MY494_07510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_07515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_07520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_07525	COG1773	rubredoxin
MY494_07530	COG4447	cellulose binding
MY494_07555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MY494_07560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MY494_07560	COG0463	Glycosyl transferase, family 2
MY494_07570	COG0463	Glycosyl transferase, family 2
MY494_07575	COG0438	transferase activity, transferring glycosyl groups
MY494_07595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MY494_07610	COG1215	transferase activity, transferring glycosyl groups
MY494_07630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY494_07635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY494_07640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MY494_07700	COG0463	Glycosyl transferase, family 2
MY494_07725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MY494_07730	COG0517	IMP dehydrogenase activity
MY494_07730	COG0617	tRNA 3'-terminal CCA addition
MY494_07730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MY494_07740	COG1132	(ABC) transporter
MY494_07755	COG5398	heme oxygenase
MY494_07765	COG0538	isocitrate dehydrogenase activity
MY494_07785	COG2192	nodulation
MY494_07795	COG0247	lactate metabolic process
MY494_07800	COG0438	transferase activity, transferring glycosyl groups
MY494_07810	COG0531	amino acid
MY494_07820	COG0277	FAD linked oxidase domain protein
MY494_07830	COG0463	Glycosyl transferase, family 2
MY494_07850	COG0724	RNA recognition motif
MY494_07855	COG0165	Argininosuccinate lyase
MY494_07860	COG2208	phosphoserine phosphatase activity
MY494_07865	COG0552	protein localization to endoplasmic reticulum
MY494_07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MY494_07885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MY494_07895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MY494_07905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY494_07915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MY494_07920	COG0497	DNA recombination
MY494_07925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MY494_07935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MY494_07940	COG0592	DNA-directed DNA polymerase activity
MY494_07955	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MY494_07960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MY494_07965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MY494_07970	COG2089	acid synthase
MY494_07985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY494_07990	COG1028	Short-chain dehydrogenase reductase Sdr
MY494_08020	COG2082	Precorrin-8x methylmutase
MY494_08025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MY494_08035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MY494_08065	COG0653	protein targeting
MY494_08070	COG1045	serine acetyltransferase
MY494_08080	COG1725	Transcriptional regulator
MY494_08085	COG0412	Dienelactone hydrolase
MY494_08090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MY494_08095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MY494_08100	COG0187	DNA topoisomerase II activity
MY494_08100	COG1372	Participates in initiation and elongation during chromosome replication
MY494_08110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MY494_08115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MY494_08120	COG0386	Belongs to the glutathione peroxidase family
MY494_08125	COG2239	Acts as a magnesium transporter
MY494_08130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_08135	COG1132	(ABC) transporter
MY494_08150	COG0802	atpase or kinase
MY494_08155	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MY494_08160	COG0629	single-stranded DNA binding
MY494_08170	COG1792	Involved in formation and maintenance of cell shape
MY494_08185	COG0745	RESPONSE REGULATOR receiver
MY494_08190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MY494_08220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY494_08250	COG1473	amidohydrolase
MY494_08265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MY494_08270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MY494_08275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MY494_08280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY494_08285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_08290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MY494_08295	COG0662	Cupin 2, conserved barrel domain protein
MY494_08295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MY494_08300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MY494_08310	COG0571	ribonuclease III activity
MY494_08335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MY494_08340	COG0058	SHG alpha-glucan phosphorylase activity
MY494_08345	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MY494_08350	COG0475	glutathione-regulated potassium exporter activity
MY494_08360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MY494_08365	COG2081	HI0933 family
MY494_08370	COG1459	type II secretion system
MY494_08380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MY494_08385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MY494_08390	COG0484	heat shock protein binding
MY494_08400	COG1162	GTPase activity
MY494_08405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MY494_08410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MY494_08415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MY494_08420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MY494_08425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MY494_08430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY494_08435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MY494_08440	COG0511	ligase activity, forming carbon-carbon bonds
MY494_08445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MY494_08470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MY494_08510	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MY494_08515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MY494_08515	COG0519	Catalyzes the synthesis of GMP from XMP
MY494_08530	COG0768	penicillin binding
MY494_08550	COG2022	thiamine diphosphate biosynthetic process
MY494_08565	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MY494_08570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MY494_08575	COG2385	sporulation resulting in formation of a cellular spore
MY494_08580	COG1215	transferase activity, transferring glycosyl groups
MY494_08585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MY494_08595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MY494_08600	COG0740	serine-type endopeptidase activity
MY494_08605	COG0544	peptidyl-prolyl cis-trans isomerase activity
MY494_08610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MY494_08615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MY494_08620	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MY494_08630	COG0037	tRNA processing
MY494_08640	COG0556	nucleotide-excision repair
MY494_08645	COG0438	transferase activity, transferring glycosyl groups
MY494_08650	COG1316	TRANSCRIPTIONal
MY494_08655	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MY494_08695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MY494_08710	COG0137	argininosuccinate synthase activity
MY494_08720	COG0360	Binds together with S18 to 16S ribosomal RNA
MY494_08730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MY494_08735	COG0443	Heat shock 70 kDa protein
MY494_08740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MY494_08755	COG0788	formyltetrahydrofolate deformylase activity
MY494_08790	COG1049	propionate catabolic process, 2-methylcitrate cycle
MY494_08795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MY494_08805	COG0170	dolichyl monophosphate biosynthetic process
MY494_08810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_08815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MY494_08825	COG0315	cyclic pyranopterin monophosphate synthase activity
MY494_08830	COG0303	'Molybdopterin
MY494_08835	COG0314	molybdopterin synthase activity
MY494_08845	COG0521	Mo-molybdopterin cofactor biosynthetic process
MY494_08850	COG0730	response to heat
MY494_08855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MY494_08860	COG0746	molybdenum cofactor guanylyltransferase activity
MY494_08865	COG2223	nitrite transmembrane transporter activity
MY494_08870	COG0243	molybdopterin cofactor binding
MY494_08890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MY494_08895	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MY494_08905	COG2116	formate transmembrane transporter activity
MY494_08915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY494_08930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MY494_08950	COG0531	amino acid
MY494_08960	COG0804	urea catabolic process
MY494_08965	COG0832	Belongs to the urease beta subunit family
MY494_08970	COG0831	urea catabolic process
MY494_08980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MY494_08985	COG0830	nickel cation binding
MY494_08990	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MY494_09030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MY494_09035	COG0602	queuosine metabolic process
MY494_09040	COG0504	CTP synthase activity
MY494_09045	COG0783	Belongs to the Dps family
MY494_09050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_09055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MY494_09060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MY494_09075	COG0010	Belongs to the arginase family
MY494_09080	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MY494_09100	COG3956	TIGRFAM MazG family protein
MY494_09105	COG2207	Transcriptional regulator
MY494_09135	COG0428	transporter
MY494_09160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MY494_09165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MY494_09170	COG0798	PFAM Bile acid sodium symporter
MY494_09220	COG4974	Belongs to the 'phage' integrase family
MY494_09225	COG0659	secondary active sulfate transmembrane transporter activity
MY494_09230	COG0300	oxidoreductase activity
MY494_09235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MY494_09255	COG0525	valine-tRNA ligase activity
MY494_09260	COG0398	Pfam SNARE associated Golgi protein
MY494_09270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MY494_09305	COG0445	tRNA wobble uridine modification
MY494_09310	COG0305	Participates in initiation and elongation during chromosome replication
MY494_09310	COG1372	Participates in initiation and elongation during chromosome replication
MY494_09310	COG0305	Participates in initiation and elongation during chromosome replication
MY494_09310	COG1372	Participates in initiation and elongation during chromosome replication
MY494_09315	COG0359	binds to the 23S rRNA
MY494_09335	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MY494_09340	COG0509	glycine decarboxylation via glycine cleavage system
MY494_09360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MY494_09360	COG0426	domain, Protein
MY494_09365	COG0426	domain, Protein
MY494_09365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MY494_09370	COG0071	Belongs to the small heat shock protein (HSP20) family
MY494_09385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MY494_09395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MY494_09405	COG1166	arginine decarboxylase activity
MY494_09410	COG0105	UTP biosynthetic process
MY494_09415	COG2022	thiamine diphosphate biosynthetic process
MY494_09415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MY494_09420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MY494_09425	COG0237	dephospho-CoA kinase activity
MY494_09430	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MY494_09445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MY494_09450	COG0148	phosphopyruvate hydratase activity
MY494_09455	COG0346	lactoylglutathione lyase activity
MY494_09460	COG0542	response to heat
MY494_09465	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MY494_09470	COG0250	Participates in transcription elongation, termination and antitermination
MY494_09475	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MY494_09480	COG0081	regulation of translation
MY494_09485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MY494_09490	COG0222	ribosome binding
MY494_09500	COG0328	RNA-DNA hybrid ribonuclease activity
MY494_09505	COG0167	dihydroorotate dehydrogenase activity
MY494_09535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MY494_09540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MY494_09575	COG0126	phosphoglycerate kinase activity
MY494_09580	COG0589	response to stress
MY494_09590	COG0564	pseudouridine synthase activity
MY494_09595	COG4172	Belongs to the ABC transporter superfamily
MY494_09600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MY494_09610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MY494_09615	COG0157	Belongs to the NadC ModD family
MY494_09620	COG0018	arginyl-trna synthetase
MY494_09625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MY494_09640	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MY494_09645	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MY494_09660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MY494_09665	COG0189	ligase activity
MY494_09670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY494_09680	COG1575	Belongs to the MenA family. Type 1 subfamily
MY494_09720	COG0649	NAD binding
MY494_09735	COG1104	cysteine desulfurase activity
MY494_09745	COG0745	RESPONSE REGULATOR receiver
MY494_09750	COG0564	pseudouridine synthase activity
MY494_09755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY494_09760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MY494_09765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MY494_09770	COG0628	permease
MY494_09775	COG0529	Catalyzes the synthesis of activated sulfate
MY494_09780	COG0023	Translation Initiation Factor
MY494_09785	COG0133	tryptophan synthase activity
MY494_09790	COG1420	regulation of RNA biosynthetic process
MY494_09795	COG1132	(ABC) transporter
MY494_09800	COG1054	Belongs to the UPF0176 family
MY494_09810	COG2062	phosphohistidine phosphatase, SixA
MY494_09815	COG0372	Belongs to the citrate synthase family
MY494_09820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MY494_09825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY494_09830	COG0839	Belongs to the complex I subunit 6 family
MY494_09835	COG0713	ATP synthesis coupled electron transport
MY494_09840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MY494_09860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MY494_09880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MY494_09890	COG0583	DNA-binding transcription factor activity
MY494_09905	COG0493	'glutamate synthase
MY494_09905	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MY494_09910	COG1562	ergosterol biosynthetic process
MY494_09920	COG0724	RNA recognition motif
MY494_09925	COG0617	tRNA 3'-terminal CCA addition
MY494_09935	COG1214	PFAM Peptidase M22, glycoprotease
MY494_09950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MY494_09955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MY494_09960	COG0416	fatty acid biosynthetic process
MY494_09970	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MY494_09975	COG0457	Tetratricopeptide repeat
MY494_09980	COG2217	Heavy metal translocating P-type atpase
MY494_09985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MY494_09990	COG0470	DNA polymerase III
MY494_09995	COG0745	RESPONSE REGULATOR receiver
MY494_10005	COG1122	ATPase activity
MY494_10020	COG2132	Multicopper oxidase
MY494_10035	COG0463	Glycosyl transferase, family 2
MY494_10050	COG3659	wide pore channel activity
MY494_10055	COG3659	wide pore channel activity
MY494_10060	COG3659	wide pore channel activity
MY494_10065	COG0484	heat shock protein binding
MY494_10075	COG1090	epimerase
MY494_10095	COG0316	Belongs to the HesB IscA family
MY494_10100	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MY494_10115	COG1587	Uroporphyrinogen-III synthase
MY494_10120	COG0457	Tetratricopeptide repeat
MY494_10120	COG0463	Glycosyl transferase, family 2
MY494_10125	COG1472	Belongs to the glycosyl hydrolase 3 family
MY494_10130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MY494_10155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MY494_10185	COG1032	radical SAM domain protein
MY494_10200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY494_10205	COG4243	Vitamin k epoxide reductase
MY494_10210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MY494_10215	COG1555	photosystem II stabilization
MY494_10225	COG1968	undecaprenyl-diphosphatase activity
MY494_10280	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
MY494_10285	COG0235	Class ii aldolase
MY494_10290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MY494_10305	COG0514	ATP-dependent DNA helicase (RecQ)
MY494_10310	COG1388	LysM domain
MY494_10310	COG3942	CHAP domain
MY494_10315	COG1012	belongs to the aldehyde dehydrogenase family
MY494_10335	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MY494_10360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MY494_10375	COG1160	GTP binding
MY494_10380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MY494_10390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MY494_10395	COG1799	cell septum assembly
MY494_10400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MY494_10405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MY494_10420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MY494_10425	COG2211	Major facilitator Superfamily
MY494_10435	COG1523	belongs to the glycosyl hydrolase 13 family
MY494_10445	COG0776	regulation of translation
MY494_10465	COG0113	porphobilinogen synthase activity
MY494_10475	COG1566	PFAM secretion protein HlyD family protein
MY494_10490	COG1193	negative regulation of DNA recombination
MY494_10495	COG3842	ATPase activity
MY494_10500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MY494_10515	COG0488	(ABC) transporter
MY494_10525	COG0435	Glutathione S-transferase
MY494_10530	COG2988	succinylglutamate desuccinylase activity
MY494_10545	COG3527	Alpha-acetolactate decarboxylase
MY494_10580	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MY494_10590	COG0195	Participates in both transcription termination and antitermination
MY494_10595	COG0779	Required for maturation of 30S ribosomal subunits
MY494_10605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MY494_10610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MY494_10615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MY494_10620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MY494_10625	COG0268	Binds directly to 16S ribosomal RNA
MY494_10630	COG0084	hydrolase, TatD family'
MY494_10635	COG0085	RNA polymerase activity
MY494_10640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MY494_10645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MY494_10650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY494_10655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MY494_10660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MY494_10690	COG0357	Ribosomal RNA small subunit methyltransferase G
MY494_10695	COG0484	heat shock protein binding
MY494_10710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MY494_10725	COG0156	8-amino-7-oxononanoate synthase activity
MY494_10730	COG4581	dead DEAH box helicase
MY494_10735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MY494_10740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MY494_10750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MY494_10755	COG0347	Belongs to the P(II) protein family
MY494_10760	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MY494_10765	COG1333	cytochrome c biogenesis protein
MY494_10775	COG0772	Belongs to the SEDS family
MY494_10795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MY494_10800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY494_10810	COG0356	it plays a direct role in the translocation of protons across the membrane
MY494_10815	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MY494_10820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MY494_10840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MY494_10850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY494_10860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY494_10865	COG3012	SEC-C Motif Domain Protein
MY494_10875	COG0686	Belongs to the AlaDH PNT family
MY494_10905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MY494_10905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY494_10910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MY494_10915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MY494_10920	COG0006	proline dipeptidase activity
MY494_10965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MY494_10975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MY494_10980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MY494_10985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MY494_10990	COG0459	protein refolding
MY494_11005	COG0004	ammonium transporteR
MY494_11010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY494_11020	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MY494_11025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MY494_11080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MY494_11100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MY494_11105	COG2264	protein methyltransferase activity
MY494_11120	COG2010	Cytochrome c
MY494_11125	COG1234	tRNA 3'-trailer cleavage
MY494_11130	COG2385	sporulation resulting in formation of a cellular spore
MY494_11135	COG0363	glucosamine-6-phosphate deaminase activity
MY494_11140	COG0217	transcriptional regulatory protein
MY494_11145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MY494_11150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MY494_11155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY494_11160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MY494_11165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MY494_11175	COG4251	negative regulation of phosphorylation
MY494_11180	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MY494_11185	COG5002	protein histidine kinase activity
MY494_11190	COG0151	Belongs to the GarS family
MY494_11200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MY494_11205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MY494_11210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MY494_11215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MY494_11220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY494_11225	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY494_11230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY494_11230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY494_11245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MY494_11260	COG2197	response regulator
MY494_11270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MY494_11280	COG0284	orotidine-5'-phosphate decarboxylase activity
MY494_11285	COG0438	transferase activity, transferring glycosyl groups
MY494_11300	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MY494_11305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MY494_11310	COG0321	lipoyl(octanoyl) transferase activity
MY494_11315	COG1022	Amp-dependent synthetase and ligase
MY494_11325	COG0508	dehydrogenase complex catalyzes the overall conversion of
MY494_11330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MY494_11335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MY494_11350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MY494_11380	COG3631	Ketosteroid isomerase-related protein
MY494_11395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MY494_11400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MY494_11405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY494_11410	COG2135	peptidase activity
MY494_11415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY494_11420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MY494_11420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MY494_11455	COG0745	RESPONSE REGULATOR receiver
MY494_11460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MY494_11465	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MY494_11470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MY494_11480	COG0196	riboflavin kinase activity
MY494_11510	COG1691	(AIR) carboxylase
MY494_11520	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MY494_11530	COG0330	HflC and HflK could
MY494_11535	COG0336	Belongs to the RNA methyltransferase TrmD family
MY494_11545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MY494_11555	COG0670	Belongs to the BI1 family
MY494_11560	COG1702	phosphate starvation-inducible protein PhoH
MY494_11565	COG0228	four-way junction DNA binding
MY494_11570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MY494_11580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MY494_11585	COG0123	including yeast histone deacetylase and acetoin utilization protein
MY494_11600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_11605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MY494_11605	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MY494_11610	COG0482	sulfurtransferase activity
MY494_11630	COG1492	cobalamin metabolic process
MY494_11660	COG0424	maF-like protein
MY494_11700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY494_11705	COG0440	acetolactate synthase activity
MY494_11810	COG2154	pterin-4-alpha-carbinolamine dehydratase
MY494_11880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MY494_12045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MY494_12055	COG0733	neurotransmitter:sodium symporter activity
MY494_12070	COG0215	cysteine-tRNA ligase activity
MY494_12075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MY494_12075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MY494_12095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY494_12115	COG0335	large ribosomal subunit rRNA binding
MY494_12125	COG0024	Methionine aminopeptidase
MY494_12130	COG0300	oxidoreductase activity
MY494_12130	COG3000	fatty acid hydroxylase
MY494_12140	COG0857	belongs to the CobB CobQ family
MY494_12155	COG1666	GTP binding
MY494_12170	COG0405	Gamma-glutamyltransferase
MY494_12175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MY494_12185	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MY494_12195	COG0277	FAD linked oxidase domain protein
MY494_12200	COG0708	Exodeoxyribonuclease III
MY494_12225	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MY494_12235	COG0735	belongs to the Fur family
MY494_12250	COG0523	cobalamin synthesis protein
MY494_12270	COG1121	(ABC) transporter
MY494_12280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MY494_12295	COG0701	Predicted permease
MY494_12310	COG0720	synthase
MY494_12315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MY494_12315	COG0140	phosphoribosyl-ATP diphosphatase activity
MY494_12320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY494_12340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY494_12345	COG3339	Conserved Protein
MY494_12390	COG2010	Cytochrome c
MY494_12405	COG0159	tryptophan synthase activity
MY494_12435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MY494_12440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MY494_12530	COG1840	ABC-type Fe3 transport system, periplasmic component
MY494_12535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY494_12555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MY494_12625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY494_12630	COG0542	response to heat
MY494_12640	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MY494_12640	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MY494_12650	COG1525	nuclease
MY494_12665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MY494_12720	COG2226	methyltransferase
MY494_12745	COG0540	Belongs to the ATCase OTCase family
MY494_12750	COG0367	asparagine synthase
MY494_12780	COG2326	polyphosphate kinase activity
MY494_12910	COG0659	secondary active sulfate transmembrane transporter activity
MY494_13110	COG4942	peptidase
MY494_13120	COG0251	oxidation-reduction process
MY494_13130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MY494_13135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MY494_13140	COG1132	(ABC) transporter
MY494_13150	COG0456	acetyltransferase
MY494_13165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain