locus-tag	class	description
SynA1524_00001	COG0592	DNA-directed DNA polymerase activity
SynA1524_00003	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynA1524_00004	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SynA1524_00005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynA1524_00007	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynA1524_00010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynA1524_00011	COG0552	protein localization to endoplasmic reticulum
SynA1524_00012	COG2208	phosphoserine phosphatase activity
SynA1524_00013	COG0165	Argininosuccinate lyase
SynA1524_00014	COG0724	RNA recognition motif
SynA1524_00015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynA1524_00016	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1524_00017	COG2081	HI0933 family
SynA1524_00018	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynA1524_00019	COG0484	heat shock protein binding
SynA1524_00021	COG1162	GTPase activity
SynA1524_00022	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynA1524_00023	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynA1524_00024	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynA1524_00026	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynA1524_00027	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynA1524_00028	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynA1524_00029	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynA1524_00030	COG0511	ligase activity, forming carbon-carbon bonds
SynA1524_00031	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynA1524_00045	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynA1524_00046	COG0519	Catalyzes the synthesis of GMP from XMP
SynA1524_00046	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynA1524_00050	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00053	COG2022	thiamine diphosphate biosynthetic process
SynA1524_00056	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynA1524_00057	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynA1524_00058	COG2385	sporulation resulting in formation of a cellular spore
SynA1524_00059	COG1215	transferase activity, transferring glycosyl groups
SynA1524_00060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynA1524_00062	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynA1524_00063	COG0740	serine-type endopeptidase activity
SynA1524_00064	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynA1524_00065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynA1524_00066	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynA1524_00067	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynA1524_00071	COG2082	Precorrin-8x methylmutase
SynA1524_00072	COG0037	tRNA processing
SynA1524_00075	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynA1524_00080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynA1524_00084	COG0556	nucleotide-excision repair
SynA1524_00093	COG2192	nodulation
SynA1524_00103	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynA1524_00107	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynA1524_00108	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynA1524_00111	COG3958	Transketolase
SynA1524_00112	COG3959	Transketolase, thiamine diphosphate binding domain
SynA1524_00118	COG2226	methyltransferase
SynA1524_00120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynA1524_00121	COG0579	oxidoreductase
SynA1524_00122	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SynA1524_00145	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00150	COG0653	protein targeting
SynA1524_00155	COG1045	serine acetyltransferase
SynA1524_00156	COG1725	Transcriptional regulator
SynA1524_00157	COG0412	Dienelactone hydrolase
SynA1524_00158	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynA1524_00159	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynA1524_00160	COG1372	Participates in initiation and elongation during chromosome replication
SynA1524_00160	COG0187	DNA topoisomerase II activity
SynA1524_00162	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynA1524_00163	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynA1524_00164	COG0386	Belongs to the glutathione peroxidase family
SynA1524_00165	COG2239	Acts as a magnesium transporter
SynA1524_00166	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1524_00169	COG0596	Alpha beta hydrolase
SynA1524_00172	COG1194	a g-specific adenine glycosylase
SynA1524_00174	COG0802	atpase or kinase
SynA1524_00175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynA1524_00176	COG0586	Pfam SNARE associated Golgi protein
SynA1524_00177	COG0629	single-stranded DNA binding
SynA1524_00182	COG0745	RESPONSE REGULATOR receiver
SynA1524_00183	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynA1524_00187	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynA1524_00188	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynA1524_00190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynA1524_00191	COG2255	four-way junction helicase activity
SynA1524_00193	COG1473	amidohydrolase
SynA1524_00196	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynA1524_00197	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynA1524_00198	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynA1524_00199	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynA1524_00200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_00201	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynA1524_00202	COG0598	Magnesium transport protein CorA
SynA1524_00203	COG0662	Cupin 2, conserved barrel domain protein
SynA1524_00203	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynA1524_00204	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynA1524_00206	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1524_00207	COG0571	ribonuclease III activity
SynA1524_00211	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SynA1524_00214	COG0058	SHG alpha-glucan phosphorylase activity
SynA1524_00215	COG0475	glutathione-regulated potassium exporter activity
SynA1524_00219	COG0277	FAD linked oxidase domain protein
SynA1524_00221	COG0247	lactate metabolic process
SynA1524_00225	COG0538	isocitrate dehydrogenase activity
SynA1524_00226	COG0463	Glycosyl transferase, family 2
SynA1524_00228	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SynA1524_00231	COG5398	heme oxygenase
SynA1524_00233	COG1132	(ABC) transporter
SynA1524_00234	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00235	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00242	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynA1524_00246	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SynA1524_00247	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SynA1524_00249	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynA1524_00250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SynA1524_00250	COG0517	IMP dehydrogenase activity
SynA1524_00251	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SynA1524_00251	COG0517	IMP dehydrogenase activity
SynA1524_00251	COG0617	tRNA 3'-terminal CCA addition
SynA1524_00252	COG0709	Synthesizes selenophosphate from selenide and ATP
SynA1524_00253	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynA1524_00255	COG2274	protein secretion by the type I secretion system
SynA1524_00257	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00258	COG0124	histidyl-tRNA synthetase
SynA1524_00260	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynA1524_00266	COG4447	cellulose binding
SynA1524_00267	COG1773	rubredoxin
SynA1524_00268	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_00269	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_00270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_00271	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynA1524_00274	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynA1524_00274	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynA1524_00276	COG0494	nUDIX hydrolase
SynA1524_00277	COG0415	Belongs to the DNA photolyase family
SynA1524_00283	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynA1524_00284	COG0131	Imidazoleglycerol-phosphate dehydratase
SynA1524_00285	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynA1524_00287	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynA1524_00291	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynA1524_00292	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynA1524_00294	COG0354	folic acid binding
SynA1524_00295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynA1524_00299	COG1253	flavin adenine dinucleotide binding
SynA1524_00300	COG0673	inositol 2-dehydrogenase activity
SynA1524_00304	COG0343	queuine tRNA-ribosyltransferase activity
SynA1524_00307	COG2205	protein histidine kinase activity
SynA1524_00311	COG0138	bifunctional purine biosynthesis protein purh
SynA1524_00314	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynA1524_00315	COG0004	ammonium transporteR
SynA1524_00316	COG1489	DNA binding
SynA1524_00317	COG0728	peptidoglycan biosynthetic process
SynA1524_00322	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynA1524_00323	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynA1524_00324	COG1058	Belongs to the CinA family
SynA1524_00324	COG1546	Belongs to the CinA family
SynA1524_00325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynA1524_00326	COG0066	3-isopropylmalate dehydratase activity
SynA1524_00333	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynA1524_00334	COG0193	aminoacyl-tRNA hydrolase activity
SynA1524_00337	COG4372	Transposase
SynA1524_00338	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1524_00339	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynA1524_00341	COG0717	Belongs to the dCTP deaminase family
SynA1524_00343	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynA1524_00345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynA1524_00346	COG2971	BadF BadG BcrA BcrD
SynA1524_00348	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynA1524_00352	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynA1524_00356	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynA1524_00357	COG1402	creatininase
SynA1524_00359	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynA1524_00360	COG2094	Belongs to the DNA glycosylase MPG family
SynA1524_00361	COG0540	Belongs to the ATCase OTCase family
SynA1524_00368	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynA1524_00371	COG0529	Catalyzes the synthesis of activated sulfate
SynA1524_00371	COG2046	Belongs to the sulfate adenylyltransferase family
SynA1524_00372	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1524_00373	COG0800	Aldolase
SynA1524_00375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynA1524_00383	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1524_00387	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynA1524_00388	COG0719	Fe-S assembly protein
SynA1524_00389	COG0396	ATPase activity
SynA1524_00390	COG0719	Fe-S assembly protein
SynA1524_00391	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynA1524_00396	COG0242	peptide deformylase activity
SynA1524_00406	COG0537	adenosine 5'-monophosphoramidase activity
SynA1524_00407	COG4178	(ABC) transporter
SynA1524_00411	COG0515	serine threonine protein kinase
SynA1524_00414	COG0439	Biotin carboxylase
SynA1524_00417	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1524_00420	COG1196	nuclear chromosome segregation
SynA1524_00428	COG0116	Belongs to the methyltransferase superfamily
SynA1524_00472	COG0300	oxidoreductase activity
SynA1524_00486	COG2089	acid synthase
SynA1524_00490	COG1083	cytidylyl-transferase
SynA1524_00492	COG3562	capsule polysaccharide
SynA1524_00493	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynA1524_00494	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynA1524_00497	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynA1524_00499	COG0347	Belongs to the P(II) protein family
SynA1524_00500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynA1524_00501	COG1333	cytochrome c biogenesis protein
SynA1524_00503	COG0772	Belongs to the SEDS family
SynA1524_00508	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SynA1524_00512	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1524_00513	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynA1524_00515	COG0356	it plays a direct role in the translocation of protons across the membrane
SynA1524_00516	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynA1524_00517	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynA1524_00518	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynA1524_00519	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynA1524_00520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynA1524_00521	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynA1524_00523	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynA1524_00525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynA1524_00526	COG3012	SEC-C Motif Domain Protein
SynA1524_00528	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynA1524_00528	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynA1524_00529	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynA1524_00530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynA1524_00531	COG1253	flavin adenine dinucleotide binding
SynA1524_00532	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynA1524_00533	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynA1524_00534	COG0006	proline dipeptidase activity
SynA1524_00535	COG0387	Pfam Sodium calcium exchanger
SynA1524_00538	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynA1524_00539	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynA1524_00541	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynA1524_00542	COG0459	protein refolding
SynA1524_00547	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SynA1524_00548	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynA1524_00551	COG0443	Heat shock 70 kDa protein
SynA1524_00560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynA1524_00564	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynA1524_00565	COG2264	protein methyltransferase activity
SynA1524_00568	COG2010	Cytochrome c
SynA1524_00569	COG1234	tRNA 3'-trailer cleavage
SynA1524_00570	COG2385	sporulation resulting in formation of a cellular spore
SynA1524_00571	COG0363	glucosamine-6-phosphate deaminase activity
SynA1524_00575	COG0217	transcriptional regulatory protein
SynA1524_00576	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynA1524_00577	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynA1524_00580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynA1524_00581	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynA1524_00584	COG4251	negative regulation of phosphorylation
SynA1524_00585	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynA1524_00586	COG5002	protein histidine kinase activity
SynA1524_00587	COG0151	Belongs to the GarS family
SynA1524_00589	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynA1524_00591	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynA1524_00592	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynA1524_00593	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynA1524_00594	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynA1524_00595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1524_00599	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynA1524_00606	COG2197	response regulator
SynA1524_00608	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynA1524_00611	COG0284	orotidine-5'-phosphate decarboxylase activity
SynA1524_00616	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynA1524_00621	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynA1524_00622	COG2211	Major facilitator Superfamily
SynA1524_00626	COG0776	regulation of translation
SynA1524_00627	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynA1524_00631	COG0668	transmembrane transport
SynA1524_00634	COG1053	succinate dehydrogenase
SynA1524_00641	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynA1524_00643	COG0195	Participates in both transcription termination and antitermination
SynA1524_00644	COG0779	Required for maturation of 30S ribosomal subunits
SynA1524_00646	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynA1524_00647	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynA1524_00648	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynA1524_00649	COG0268	Binds directly to 16S ribosomal RNA
SynA1524_00650	COG0084	hydrolase, TatD family'
SynA1524_00651	COG0085	RNA polymerase activity
SynA1524_00652	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynA1524_00654	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynA1524_00656	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynA1524_00666	COG0357	Ribosomal RNA small subunit methyltransferase G
SynA1524_00667	COG0484	heat shock protein binding
SynA1524_00668	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynA1524_00671	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynA1524_00674	COG0156	8-amino-7-oxononanoate synthase activity
SynA1524_00675	COG0385	Bile acid
SynA1524_00676	COG4581	dead DEAH box helicase
SynA1524_00677	COG0114	fumarate hydratase activity
SynA1524_00681	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00681	COG1216	Glycosyl transferase, family 2
SynA1524_00685	COG1216	Glycosyl transferase, family 2
SynA1524_00685	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00692	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynA1524_00695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynA1524_00698	COG1160	GTP binding
SynA1524_00699	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynA1524_00701	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynA1524_00702	COG1799	cell septum assembly
SynA1524_00703	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynA1524_00704	COG0438	transferase activity, transferring glycosyl groups
SynA1524_00706	COG1381	Involved in DNA repair and RecF pathway recombination
SynA1524_00707	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynA1524_00708	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynA1524_00709	COG0321	lipoyl(octanoyl) transferase activity
SynA1524_00710	COG1022	Amp-dependent synthetase and ligase
SynA1524_00712	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynA1524_00713	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynA1524_00722	COG2608	mercury ion transmembrane transporter activity
SynA1524_00722	COG2217	Heavy metal translocating P-type atpase
SynA1524_00725	COG2119	membrane
SynA1524_00727	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynA1524_00733	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynA1524_00734	COG0440	acetolactate synthase activity
SynA1524_00735	COG2267	carboxylic ester hydrolase activity
SynA1524_00740	COG2226	methyltransferase
SynA1524_00743	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynA1524_00744	COG0492	ferredoxin-NADP+ reductase activity
SynA1524_00756	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynA1524_00757	COG0733	neurotransmitter:sodium symporter activity
SynA1524_00759	COG0215	cysteine-tRNA ligase activity
SynA1524_00760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynA1524_00760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynA1524_00761	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynA1524_00762	COG0012	GTP binding
SynA1524_00765	COG0601	transmembrane transport
SynA1524_00766	COG4533	DNA binding
SynA1524_00768	COG0460	homoserine dehydrogenase
SynA1524_00769	COG2166	iron-sulfur cluster assembly
SynA1524_00771	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynA1524_00772	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynA1524_00773	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynA1524_00777	COG2010	Cytochrome c
SynA1524_00779	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynA1524_00780	COG3118	belongs to the thioredoxin family
SynA1524_00781	COG0516	GMP reductase activity
SynA1524_00783	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynA1524_00784	COG0644	oxidoreductase
SynA1524_00785	COG1543	Belongs to the glycosyl hydrolase 57 family
SynA1524_00786	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynA1524_00787	COG0395	ABC-type sugar transport system, permease component
SynA1524_00792	COG0011	TIGRFAM Protein of
SynA1524_00794	COG0564	pseudouridine synthase activity
SynA1524_00796	COG1480	7TM receptor with intracellular HD hydrolase
SynA1524_00797	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynA1524_00801	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynA1524_00807	COG1254	Belongs to the acylphosphatase family
SynA1524_00808	COG1797	cobyrinic acid a,c-diamide synthase activity
SynA1524_00810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynA1524_00815	COG2205	protein histidine kinase activity
SynA1524_00818	COG0308	aminopeptidase N
SynA1524_00832	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynA1524_00841	COG1376	ErfK ybiS ycfS ynhG family protein
SynA1524_00844	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SynA1524_00846	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynA1524_00848	COG2197	response regulator
SynA1524_00849	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynA1524_00852	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynA1524_00855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynA1524_00856	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynA1524_00857	COG0473	3-isopropylmalate dehydrogenase activity
SynA1524_00858	COG3954	Phosphoribulokinase
SynA1524_00860	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynA1524_00861	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynA1524_00863	COG0673	inositol 2-dehydrogenase activity
SynA1524_00864	COG0191	fructose-bisphosphate aldolase activity
SynA1524_00865	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynA1524_00866	COG0047	phosphoribosylformylglycinamidine synthase activity
SynA1524_00867	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynA1524_00869	COG0668	transmembrane transport
SynA1524_00871	COG0640	Transcriptional regulator
SynA1524_00872	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynA1524_00882	COG5002	protein histidine kinase activity
SynA1524_00889	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynA1524_00892	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1524_00894	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynA1524_00895	COG1429	ligase activity, forming nitrogen-metal bonds
SynA1524_00897	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynA1524_00898	COG0149	triose-phosphate isomerase activity
SynA1524_00900	COG1132	(ABC) transporter
SynA1524_00902	COG1115	amino acid carrier protein
SynA1524_00904	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynA1524_00906	COG0799	negative regulation of ribosome biogenesis
SynA1524_00914	COG0659	secondary active sulfate transmembrane transporter activity
SynA1524_00916	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynA1524_00917	COG4597	amino acid ABC transporter
SynA1524_00918	COG0765	amino acid transport
SynA1524_00919	COG1126	abc transporter atp-binding protein
SynA1524_00927	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynA1524_00934	COG0625	glutathione transferase activity
SynA1524_00941	COG1799	cell septum assembly
SynA1524_00944	COG0735	belongs to the Fur family
SynA1524_00945	COG2197	response regulator
SynA1524_00948	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SynA1524_00956	COG0259	pyridoxamine-phosphate oxidase activity
SynA1524_00958	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynA1524_00968	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SynA1524_00970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynA1524_00976	COG0745	RESPONSE REGULATOR receiver
SynA1524_00978	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynA1524_00979	COG0271	Belongs to the BolA IbaG family
SynA1524_00982	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynA1524_00985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SynA1524_00986	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynA1524_00990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynA1524_00992	COG0513	Belongs to the DEAD box helicase family
SynA1524_00995	COG0724	RNA recognition motif
SynA1524_00996	COG1132	(ABC) transporter
SynA1524_00997	COG0475	glutathione-regulated potassium exporter activity
SynA1524_00997	COG0589	response to stress
SynA1524_01000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynA1524_01001	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynA1524_01007	COG1054	Belongs to the UPF0176 family
SynA1524_01008	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynA1524_01009	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynA1524_01010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynA1524_01011	COG0019	diaminopimelate decarboxylase activity
SynA1524_01012	COG0456	acetyltransferase
SynA1524_01013	COG0542	response to heat
SynA1524_01014	COG0371	Dehydrogenase
SynA1524_01015	COG0596	Alpha beta hydrolase
SynA1524_01017	COG0575	Belongs to the CDS family
SynA1524_01018	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynA1524_01019	COG1982	Orn Lys Arg decarboxylase major
SynA1524_01020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynA1524_01022	COG0745	RESPONSE REGULATOR receiver
SynA1524_01023	COG5002	protein histidine kinase activity
SynA1524_01024	COG1187	pseudouridine synthase activity
SynA1524_01025	COG1640	4-alpha-glucanotransferase
SynA1524_01029	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynA1524_01032	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynA1524_01033	COG1121	(ABC) transporter
SynA1524_01038	COG0701	Predicted permease
SynA1524_01051	COG0540	Belongs to the ATCase OTCase family
SynA1524_01052	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynA1524_01064	COG0681	Belongs to the peptidase S26 family
SynA1524_01065	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynA1524_01066	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SynA1524_01067	COG1376	ErfK ybiS ycfS ynhG family protein
SynA1524_01068	COG0297	glycogen (starch) synthase activity
SynA1524_01070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynA1524_01071	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynA1524_01073	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynA1524_01074	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynA1524_01075	COG2045	Belongs to the ComB family
SynA1524_01077	COG0860	N-Acetylmuramoyl-L-alanine amidase
SynA1524_01078	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynA1524_01079	COG0142	geranyltranstransferase activity
SynA1524_01080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynA1524_01081	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynA1524_01083	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynA1524_01084	COG2176	DNA-directed DNA polymerase activity
SynA1524_01087	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1524_01091	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1524_01093	COG1132	(ABC) transporter
SynA1524_01095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynA1524_01096	COG0505	Belongs to the CarA family
SynA1524_01098	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynA1524_01099	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynA1524_01101	COG0154	amidase activity
SynA1524_01102	COG0587	DNA-directed DNA polymerase activity
SynA1524_01104	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynA1524_01105	COG0632	four-way junction helicase activity
SynA1524_01106	COG1006	Multisubunit Na H antiporter MnhC subunit
SynA1524_01107	COG1007	ATP synthesis coupled electron transport
SynA1524_01115	COG1809	phosphosulfolactate synthase activity
SynA1524_01120	COG0358	DNA primase activity
SynA1524_01121	COG0798	PFAM Bile acid sodium symporter
SynA1524_01125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynA1524_01129	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynA1524_01132	COG0792	nuclease activity
SynA1524_01136	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynA1524_01137	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynA1524_01139	COG0022	dehydrogenase e1 component
SynA1524_01139	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynA1524_01140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynA1524_01141	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynA1524_01154	COG0628	permease
SynA1524_01156	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynA1524_01157	COG0515	serine threonine protein kinase
SynA1524_01162	COG2226	methyltransferase
SynA1524_01163	COG0174	glutamine synthetase
SynA1524_01165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynA1524_01166	COG0590	tRNA wobble adenosine to inosine editing
SynA1524_01169	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynA1524_01173	COG0612	Peptidase, M16
SynA1524_01179	COG1216	Glycosyl transferase, family 2
SynA1524_01181	COG0052	Belongs to the universal ribosomal protein uS2 family
SynA1524_01182	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynA1524_01184	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynA1524_01185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynA1524_01186	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynA1524_01187	COG0751	glycine-tRNA ligase activity
SynA1524_01189	COG0644	oxidoreductase
SynA1524_01191	COG0826	peptidase U32
SynA1524_01192	COG1217	gtp-binding protein TYPA
SynA1524_01197	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynA1524_01199	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynA1524_01200	COG1494	fructose-1,6-bisphosphatase
SynA1524_01201	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynA1524_01202	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1524_01203	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynA1524_01204	COG0363	glucosamine-6-phosphate deaminase activity
SynA1524_01208	COG0129	dihydroxy-acid dehydratase activity
SynA1524_01210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynA1524_01231	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SynA1524_01232	COG4106	trans-aconitate 2-methyltransferase activity
SynA1524_01233	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynA1524_01237	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynA1524_01242	COG1836	PFAM Integral membrane protein DUF92
SynA1524_01248	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynA1524_01249	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynA1524_01250	COG0436	Aminotransferase
SynA1524_01252	COG1573	uracil-dna glycosylase
SynA1524_01253	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynA1524_01254	COG0793	Belongs to the peptidase S41A family
SynA1524_01256	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynA1524_01261	COG0861	Integral membrane protein TerC family
SynA1524_01266	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynA1524_01268	COG0312	modulator of DNA gyrase
SynA1524_01269	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynA1524_01272	COG0163	prenyltransferase activity
SynA1524_01273	COG0557	exoribonuclease II activity
SynA1524_01275	COG2119	membrane
SynA1524_01278	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynA1524_01278	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynA1524_01282	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynA1524_01283	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1524_01284	COG1615	UPF0182 protein
SynA1524_01285	COG0450	alkyl hydroperoxide reductase
SynA1524_01287	COG0739	heme binding
SynA1524_01288	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynA1524_01294	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynA1524_01296	COG0557	exoribonuclease II activity
SynA1524_01297	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynA1524_01298	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynA1524_01299	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynA1524_01299	COG0072	phenylalanine-tRNA ligase activity
SynA1524_01300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynA1524_01312	COG0646	methionine synthase
SynA1524_01312	COG1410	methionine synthase
SynA1524_01314	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynA1524_01317	COG0613	PHP domain protein
SynA1524_01318	COG1981	membrane
SynA1524_01319	COG3046	protein related to deoxyribodipyrimidine photolyase
SynA1524_01321	COG0322	excinuclease ABC activity
SynA1524_01323	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynA1524_01329	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynA1524_01331	COG0495	leucyl-tRNA aminoacylation
SynA1524_01332	COG0166	Belongs to the GPI family
SynA1524_01338	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynA1524_01339	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynA1524_01340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynA1524_01340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynA1524_01341	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynA1524_01342	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynA1524_01343	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynA1524_01346	COG0443	Heat shock 70 kDa protein
SynA1524_01347	COG0573	inorganic phosphate transmembrane transporter activity
SynA1524_01348	COG0581	inorganic phosphate transmembrane transporter activity
SynA1524_01349	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynA1524_01351	COG0633	Ferredoxin
SynA1524_01352	COG0483	inositol monophosphate 1-phosphatase activity
SynA1524_01353	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynA1524_01355	COG0326	Molecular chaperone. Has ATPase activity
SynA1524_01356	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynA1524_01357	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynA1524_01358	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynA1524_01359	COG1653	transport
SynA1524_01362	COG3842	ATPase activity
SynA1524_01365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynA1524_01370	COG0644	oxidoreductase
SynA1524_01371	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynA1524_01372	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynA1524_01377	COG0469	pyruvate kinase activity
SynA1524_01378	COG0577	efflux transmembrane transporter activity
SynA1524_01378	COG1136	(ABC) transporter
SynA1524_01379	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1524_01382	COG0740	serine-type endopeptidase activity
SynA1524_01388	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynA1524_01392	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynA1524_01393	COG1175	transmembrane transport
SynA1524_01394	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynA1524_01405	COG1793	dna ligase
SynA1524_01407	COG1201	RNA secondary structure unwinding
SynA1524_01410	COG2059	Chromate
SynA1524_01422	COG2226	methyltransferase
SynA1524_01431	COG1119	ATPase activity
SynA1524_01433	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynA1524_01439	COG1121	(ABC) transporter
SynA1524_01440	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynA1524_01441	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynA1524_01442	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynA1524_01469	COG0724	RNA recognition motif
SynA1524_01490	COG2197	response regulator
SynA1524_01494	COG2197	response regulator
SynA1524_01506	COG0405	Gamma-glutamyltransferase
SynA1524_01524	COG2124	cytochrome p450
SynA1524_01531	COG0010	Belongs to the arginase family
SynA1524_01532	COG0375	protein maturation
SynA1524_01535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SynA1524_01536	COG1116	anion transmembrane transporter activity
SynA1524_01541	COG2144	transferase activity, transferring acyl groups
SynA1524_01546	COG2072	flavoprotein involved in K transport
SynA1524_01549	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SynA1524_01576	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynA1524_01585	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1524_01612	COG0180	Tryptophanyl-tRNA synthetase
SynA1524_01615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynA1524_01617	COG0837	glucose binding
SynA1524_01618	COG0083	homoserine kinase activity
SynA1524_01619	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_01620	COG0339	signal peptide processing
SynA1524_01623	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynA1524_01632	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynA1524_01633	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynA1524_01635	COG3794	PFAM blue (type 1) copper domain protein
SynA1524_01641	COG0542	response to heat
SynA1524_01642	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SynA1524_01644	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynA1524_01644	COG0140	phosphoribosyl-ATP diphosphatase activity
SynA1524_01648	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1524_01655	COG2010	Cytochrome c
SynA1524_01658	COG0159	tryptophan synthase activity
SynA1524_01663	COG0418	dihydroorotase activity
SynA1524_01664	COG0659	secondary active sulfate transmembrane transporter activity
SynA1524_01665	COG0530	calcium, potassium:sodium antiporter activity
SynA1524_01669	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynA1524_01670	COG1845	cytochrome c oxidase, subunit III
SynA1524_01673	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynA1524_01677	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynA1524_01678	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynA1524_01681	COG0456	acetyltransferase
SynA1524_01682	COG1132	(ABC) transporter
SynA1524_01683	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynA1524_01684	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynA1524_01685	COG3842	ATPase activity
SynA1524_01696	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynA1524_01700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynA1524_01701	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1524_01702	COG2135	peptidase activity
SynA1524_01705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynA1524_01705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynA1524_01721	COG0745	RESPONSE REGULATOR receiver
SynA1524_01722	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynA1524_01723	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynA1524_01724	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynA1524_01726	COG0196	riboflavin kinase activity
SynA1524_01728	COG0352	thiamine-phosphate diphosphorylase activity
SynA1524_01733	COG1691	(AIR) carboxylase
SynA1524_01735	COG0336	Belongs to the RNA methyltransferase TrmD family
SynA1524_01738	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynA1524_01740	COG0670	Belongs to the BI1 family
SynA1524_01741	COG1702	phosphate starvation-inducible protein PhoH
SynA1524_01742	COG0228	four-way junction DNA binding
SynA1524_01743	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynA1524_01745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynA1524_01746	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1524_01747	COG0482	sulfurtransferase activity
SynA1524_01748	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynA1524_01754	COG0134	indole-3-glycerol-phosphate synthase activity
SynA1524_01755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynA1524_01756	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynA1524_01759	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynA1524_01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynA1524_01761	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynA1524_01762	COG0285	dihydrofolate synthase activity
SynA1524_01768	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynA1524_01769	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynA1524_01772	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynA1524_01773	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynA1524_01774	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynA1524_01775	COG4956	integral membrane protein (PIN domain superfamily)
SynA1524_01776	COG0740	serine-type endopeptidase activity
SynA1524_01777	COG0740	serine-type endopeptidase activity
SynA1524_01778	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynA1524_01779	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynA1524_01786	COG0752	glycyl-tRNA synthetase alpha subunit
SynA1524_01789	COG2226	methyltransferase
SynA1524_01790	COG0107	imidazoleglycerol-phosphate synthase activity
SynA1524_01792	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynA1524_01793	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynA1524_01794	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynA1524_01794	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynA1524_01795	COG3695	enzyme binding
SynA1524_01797	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynA1524_01802	COG0481	GTPase activity
SynA1524_01804	COG0579	oxidoreductase
SynA1524_01805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynA1524_01812	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1524_01821	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SynA1524_01826	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynA1524_01828	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SynA1524_01829	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SynA1524_01836	COG3239	Fatty acid desaturase
SynA1524_01845	COG0424	maF-like protein
SynA1524_01847	COG1492	cobalamin metabolic process
SynA1524_01855	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_01856	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynA1524_01857	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynA1524_01862	COG4451	ribulose bisphosphate carboxylase, small
SynA1524_01863	COG1850	ribulose-bisphosphate carboxylase activity
SynA1524_01864	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynA1524_01866	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynA1524_01867	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynA1524_01869	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynA1524_01870	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynA1524_01871	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynA1524_01876	COG0730	response to heat
SynA1524_01877	COG0095	Lipoate-protein ligase
SynA1524_01878	COG1994	Peptidase M50
SynA1524_01878	COG0517	IMP dehydrogenase activity
SynA1524_01879	COG0135	phosphoribosylanthranilate isomerase activity
SynA1524_01880	COG0302	gtp cyclohydrolase
SynA1524_01881	COG4221	oxidoreductase activity
SynA1524_01882	COG0825	malonyl-CoA metabolic process
SynA1524_01883	COG5322	oxidoreductase activity
SynA1524_01884	COG3396	Phenylacetate-CoA oxygenase
SynA1524_01886	COG0539	negative regulation of cytoplasmic translation
SynA1524_01888	COG1496	oxidoreductase activity
SynA1524_01889	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynA1524_01893	COG0028	Belongs to the TPP enzyme family
SynA1524_01894	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1524_01896	COG2226	methyltransferase
SynA1524_01899	COG0528	UMP kinase activity
SynA1524_01900	COG0233	cytoplasmic translational termination
SynA1524_01901	COG0644	oxidoreductase
SynA1524_01902	COG0415	Belongs to the DNA photolyase family
SynA1524_01904	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynA1524_01905	COG0768	penicillin binding
SynA1524_01908	COG0588	phosphoglycerate mutase activity
SynA1524_01914	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynA1524_01916	COG0442	prolyl-tRNA aminoacylation
SynA1524_01918	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynA1524_01919	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynA1524_01921	COG0629	single-stranded DNA binding
SynA1524_01924	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynA1524_01926	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynA1524_01927	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1524_01940	COG0181	hydroxymethylbilane synthase activity
SynA1524_01943	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynA1524_01949	COG0432	Pfam Uncharacterised protein family UPF0047
SynA1524_01950	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynA1524_01951	COG0523	cobalamin synthesis protein
SynA1524_01953	COG1840	ABC-type Fe3 transport system, periplasmic component
SynA1524_01958	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynA1524_01959	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1524_01963	COG0708	Exodeoxyribonuclease III
SynA1524_01964	COG0277	FAD linked oxidase domain protein
SynA1524_01965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynA1524_01967	COG0295	cytidine deaminase activity
SynA1524_01972	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SynA1524_01978	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynA1524_01979	COG1666	GTP binding
SynA1524_01982	COG0857	belongs to the CobB CobQ family
SynA1524_01984	COG0300	oxidoreductase activity
SynA1524_01984	COG3000	fatty acid hydroxylase
SynA1524_01985	COG0024	Methionine aminopeptidase
SynA1524_01987	COG0335	large ribosomal subunit rRNA binding
SynA1524_01992	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynA1524_01998	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1524_01999	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynA1524_02002	COG0194	GDP metabolic process
SynA1524_02003	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SynA1524_02004	COG0805	protein transport
SynA1524_02006	COG0723	plastoquinol--plastocyanin reductase activity
SynA1524_02007	COG0739	heme binding
SynA1524_02008	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SynA1524_02009	COG2875	Belongs to the precorrin methyltransferase family
SynA1524_02013	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynA1524_02014	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynA1524_02015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynA1524_02018	COG1028	Short-chain dehydrogenase reductase Sdr
SynA1524_02020	COG0459	protein refolding
SynA1524_02021	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynA1524_02025	COG0109	protoheme IX farnesyltransferase activity
SynA1524_02027	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SynA1524_02029	COG1845	cytochrome c oxidase, subunit III
SynA1524_02035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynA1524_02038	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynA1524_02039	COG1007	ATP synthesis coupled electron transport
SynA1524_02040	COG0577	efflux transmembrane transporter activity
SynA1524_02040	COG1136	(ABC) transporter
SynA1524_02042	COG0739	heme binding
SynA1524_02044	COG0436	Aminotransferase
SynA1524_02045	COG3118	belongs to the thioredoxin family
SynA1524_02046	COG1842	Phage shock protein A
SynA1524_02048	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SynA1524_02049	COG0438	transferase activity, transferring glycosyl groups
SynA1524_02050	COG0697	spore germination
SynA1524_02051	COG0616	signal peptide processing
SynA1524_02054	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynA1524_02055	COG0594	ribonuclease P activity
SynA1524_02057	COG0706	membrane insertase activity
SynA1524_02059	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1524_02061	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynA1524_02062	COG0750	zinc metalloprotease
SynA1524_02063	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynA1524_02064	COG1185	polyribonucleotide nucleotidyltransferase activity
SynA1524_02065	COG1218	3'(2'),5'-bisphosphate nucleotidase
SynA1524_02066	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynA1524_02092	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynA1524_02093	COG2226	methyltransferase
SynA1524_02096	COG4176	ABC-type proline glycine betaine transport system permease component
SynA1524_02097	COG2113	Glycine betaine
SynA1524_02103	COG2988	succinylglutamate desuccinylase activity
SynA1524_02104	COG0435	Glutathione S-transferase
SynA1524_02106	COG0488	(ABC) transporter
SynA1524_02109	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynA1524_02110	COG3842	ATPase activity
SynA1524_02112	COG1193	negative regulation of DNA recombination
SynA1524_02114	COG0113	porphobilinogen synthase activity
SynA1524_02115	COG0484	heat shock protein binding
SynA1524_02116	COG4243	Vitamin k epoxide reductase
SynA1524_02117	COG0659	secondary active sulfate transmembrane transporter activity
SynA1524_02135	COG3659	wide pore channel activity
SynA1524_02140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynA1524_02144	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SynA1524_02145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynA1524_02147	COG1012	belongs to the aldehyde dehydrogenase family
SynA1524_02148	COG0741	lytic transglycosylase activity
SynA1524_02148	COG1388	LysM domain
SynA1524_02152	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynA1524_02153	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynA1524_02154	COG0235	Class ii aldolase
SynA1524_02155	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynA1524_02163	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynA1524_02164	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynA1524_02165	COG0793	Belongs to the peptidase S41A family
SynA1524_02166	COG1078	dGTPase activity
SynA1524_02167	COG0850	regulation of cytokinetic process
SynA1524_02168	COG2894	cell division
SynA1524_02169	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynA1524_02173	COG0009	L-threonylcarbamoyladenylate synthase
SynA1524_02174	COG2890	protein-(glutamine-N5) methyltransferase activity
SynA1524_02175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynA1524_02175	COG0758	DNA mediated transformation
SynA1524_02181	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynA1524_02183	COG0539	negative regulation of cytoplasmic translation
SynA1524_02184	COG0546	phosphoglycolate phosphatase activity
SynA1524_02185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynA1524_02186	COG1070	Carbohydrate kinase
SynA1524_02190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynA1524_02197	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1524_02228	COG1413	lyase activity
SynA1524_02229	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynA1524_02230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynA1524_02230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynA1524_02231	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynA1524_02233	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynA1524_02241	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SynA1524_02245	COG0408	coproporphyrinogen oxidase activity
SynA1524_02247	COG0489	protein tyrosine kinase activity
SynA1524_02248	COG0772	Belongs to the SEDS family
SynA1524_02251	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynA1524_02253	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynA1524_02256	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynA1524_02257	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynA1524_02258	COG1606	tRNA processing
SynA1524_02259	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynA1524_02268	COG3001	Fructosamine kinase
SynA1524_02269	COG1233	COG1233 Phytoene dehydrogenase and related
SynA1524_02274	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynA1524_02277	COG3854	ATPases associated with a variety of cellular activities
SynA1524_02280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynA1524_02281	COG0088	Forms part of the polypeptide exit tunnel
SynA1524_02282	COG0089	rRNA binding
SynA1524_02283	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynA1524_02284	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynA1524_02285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynA1524_02286	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynA1524_02287	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynA1524_02288	COG0255	Belongs to the universal ribosomal protein uL29 family
SynA1524_02289	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynA1524_02290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynA1524_02291	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynA1524_02292	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynA1524_02293	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynA1524_02294	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynA1524_02295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynA1524_02296	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynA1524_02297	COG0200	Binds to the 23S rRNA
SynA1524_02298	COG0201	protein transport
SynA1524_02299	COG0563	adenylate kinase activity
SynA1524_02300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynA1524_02301	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynA1524_02302	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynA1524_02303	COG0202	RNA polymerase activity
SynA1524_02304	COG0203	ribosomal protein L17
SynA1524_02305	COG0101	tRNA pseudouridine synthase activity
SynA1524_02306	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynA1524_02307	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynA1524_02308	COG0254	rRNA binding
SynA1524_02309	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynA1524_02311	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynA1524_02315	COG0463	Glycosyl transferase, family 2
SynA1524_02324	COG2885	chlorophyll binding
SynA1524_02325	COG2885	chlorophyll binding
SynA1524_02331	COG3659	wide pore channel activity
SynA1524_02335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynA1524_02337	COG0069	glutamate synthase activity
SynA1524_02337	COG0070	glutamate synthase
SynA1524_02337	COG0067	glutamate synthase
SynA1524_02340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynA1524_02341	COG0049	tRNA binding
SynA1524_02342	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynA1524_02343	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynA1524_02344	COG0051	transcription antitermination factor activity, RNA binding
SynA1524_02345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynA1524_02346	COG2226	methyltransferase
SynA1524_02349	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynA1524_02350	COG1530	ribonuclease E activity
SynA1524_02353	COG0436	Aminotransferase
SynA1524_02354	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynA1524_02361	COG0033	Phosphoglucomutase
SynA1524_02363	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynA1524_02365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SynA1524_02369	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynA1524_02370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynA1524_02371	COG0175	sulfate reduction
SynA1524_02372	COG1252	NADH dehydrogenase
SynA1524_02373	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynA1524_02374	COG0471	metal ion transport
SynA1524_02374	COG3273	potassium ion transport
SynA1524_02375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynA1524_02376	COG0569	domain protein
SynA1524_02377	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynA1524_02382	COG0488	(ABC) transporter
SynA1524_02384	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynA1524_02388	COG1643	Atp-dependent helicase
SynA1524_02389	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1524_02391	COG1570	exodeoxyribonuclease VII activity
SynA1524_02392	COG1722	exodeoxyribonuclease VII activity
SynA1524_02405	COG1968	undecaprenyl-diphosphatase activity
SynA1524_02407	COG1555	photosystem II stabilization
SynA1524_02408	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynA1524_02409	COG4243	Vitamin k epoxide reductase
SynA1524_02411	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynA1524_02413	COG1032	radical SAM domain protein
SynA1524_02420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynA1524_02425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynA1524_02426	COG1472	Belongs to the glycosyl hydrolase 3 family
SynA1524_02427	COG0457	Tetratricopeptide repeat
SynA1524_02427	COG0463	Glycosyl transferase, family 2
SynA1524_02428	COG1587	Uroporphyrinogen-III synthase
SynA1524_02431	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynA1524_02432	COG0316	Belongs to the HesB IscA family
SynA1524_02435	COG1090	epimerase
SynA1524_02439	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynA1524_02440	COG3659	wide pore channel activity
SynA1524_02441	COG3659	wide pore channel activity
SynA1524_02444	COG3659	wide pore channel activity
SynA1524_02445	COG3659	wide pore channel activity
SynA1524_02454	COG1122	ATPase activity
SynA1524_02457	COG0745	RESPONSE REGULATOR receiver
SynA1524_02459	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynA1524_02460	COG2217	Heavy metal translocating P-type atpase
SynA1524_02461	COG3063	Type IV pilus biogenesis stability protein PilW
SynA1524_02462	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynA1524_02464	COG0416	fatty acid biosynthetic process
SynA1524_02465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynA1524_02466	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynA1524_02469	COG1214	PFAM Peptidase M22, glycoprotease
SynA1524_02471	COG0617	tRNA 3'-terminal CCA addition
SynA1524_02472	COG0724	RNA recognition motif
SynA1524_02473	COG1562	ergosterol biosynthetic process
SynA1524_02474	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynA1524_02474	COG0493	'glutamate synthase
SynA1524_02478	COG0583	DNA-binding transcription factor activity
SynA1524_02480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynA1524_02481	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_02484	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynA1524_02486	COG2197	response regulator
SynA1524_02488	COG2954	triphosphatase activity
SynA1524_02489	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynA1524_02490	COG0713	ATP synthesis coupled electron transport
SynA1524_02491	COG0839	Belongs to the complex I subunit 6 family
SynA1524_02492	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1524_02493	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynA1524_02494	COG0372	Belongs to the citrate synthase family
SynA1524_02495	COG2062	phosphohistidine phosphatase, SixA
SynA1524_02498	COG1420	regulation of RNA biosynthetic process
SynA1524_02499	COG0133	tryptophan synthase activity
SynA1524_02500	COG0023	Translation Initiation Factor
SynA1524_02501	COG0529	Catalyzes the synthesis of activated sulfate
SynA1524_02502	COG0628	permease
SynA1524_02503	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynA1524_02504	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SynA1524_02505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynA1524_02506	COG0564	pseudouridine synthase activity
SynA1524_02507	COG0745	RESPONSE REGULATOR receiver
SynA1524_02509	COG1104	cysteine desulfurase activity
SynA1524_02511	COG0275	rRNA processing
SynA1524_02512	COG0649	NAD binding
SynA1524_02514	COG0824	Thioesterase
SynA1524_02517	COG0318	PFAM AMP-dependent synthetase and ligase
SynA1524_02519	COG1575	Belongs to the MenA family. Type 1 subfamily
SynA1524_02521	COG0189	ligase activity
SynA1524_02522	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynA1524_02523	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynA1524_02525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynA1524_02526	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynA1524_02527	COG0512	Glutamine amidotransferase of anthranilate synthase
SynA1524_02529	COG0252	asparaginase activity
SynA1524_02530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynA1524_02531	COG0018	arginyl-trna synthetase
SynA1524_02532	COG0157	Belongs to the NadC ModD family
SynA1524_02535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynA1524_02537	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynA1524_02538	COG4172	Belongs to the ABC transporter superfamily
SynA1524_02540	COG0564	pseudouridine synthase activity
SynA1524_02542	COG0589	response to stress
SynA1524_02543	COG0126	phosphoglycerate kinase activity
SynA1524_02547	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynA1524_02548	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynA1524_02552	COG0167	dihydroorotate dehydrogenase activity
SynA1524_02553	COG0328	RNA-DNA hybrid ribonuclease activity
SynA1524_02555	COG0222	ribosome binding
SynA1524_02556	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynA1524_02558	COG0081	regulation of translation
SynA1524_02559	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynA1524_02560	COG0250	Participates in transcription elongation, termination and antitermination
SynA1524_02561	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynA1524_02562	COG0542	response to heat
SynA1524_02563	COG0346	lactoylglutathione lyase activity
SynA1524_02564	COG0148	phosphopyruvate hydratase activity
SynA1524_02565	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynA1524_02568	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynA1524_02569	COG0237	dephospho-CoA kinase activity
SynA1524_02571	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynA1524_02572	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynA1524_02572	COG2022	thiamine diphosphate biosynthetic process
SynA1524_02576	COG0105	UTP biosynthetic process
SynA1524_02582	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynA1524_02584	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynA1524_02587	COG0071	Belongs to the small heat shock protein (HSP20) family
SynA1524_02589	COG0426	domain, Protein
SynA1524_02589	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynA1524_02590	COG0426	domain, Protein
SynA1524_02590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynA1524_02591	COG1773	rubredoxin
SynA1524_02593	COG1733	regulation of RNA biosynthetic process
SynA1524_02595	COG1741	Belongs to the pirin family
SynA1524_02599	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SynA1524_02599	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SynA1524_02600	COG0509	glycine decarboxylation via glycine cleavage system
SynA1524_02601	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynA1524_02603	COG0359	binds to the 23S rRNA
SynA1524_02604	COG0305	Participates in initiation and elongation during chromosome replication
SynA1524_02604	COG0305	Participates in initiation and elongation during chromosome replication
SynA1524_02604	COG1372	Participates in initiation and elongation during chromosome replication
SynA1524_02604	COG1372	Participates in initiation and elongation during chromosome replication
SynA1524_02605	COG0445	tRNA wobble uridine modification
SynA1524_02613	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynA1524_02614	COG0737	Belongs to the 5'-nucleotidase family
SynA1524_02617	COG0398	Pfam SNARE associated Golgi protein
SynA1524_02621	COG0525	valine-tRNA ligase activity
SynA1524_02626	COG4221	oxidoreductase activity
SynA1524_02655	COG3956	TIGRFAM MazG family protein
SynA1524_02657	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynA1524_02658	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynA1524_02659	COG0010	Belongs to the arginase family
SynA1524_02662	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynA1524_02663	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynA1524_02664	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1524_02665	COG0504	CTP synthase activity
SynA1524_02666	COG0602	queuosine metabolic process
SynA1524_02669	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynA1524_02673	COG0366	Alpha amylase catalytic
SynA1524_02674	COG0463	Glycosyl transferase, family 2
SynA1524_02687	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynA1524_02688	COG0830	nickel cation binding
SynA1524_02689	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynA1524_02690	COG0829	nickel cation binding
SynA1524_02691	COG0831	urea catabolic process
SynA1524_02692	COG0832	Belongs to the urease beta subunit family
SynA1524_02693	COG0804	urea catabolic process
SynA1524_02697	COG0367	asparagine synthase
SynA1524_02698	COG0540	Belongs to the ATCase OTCase family
SynA1524_02702	COG2308	Evidence 4 Homologs of previously reported genes of
SynA1524_02706	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynA1524_02707	COG0746	molybdenum cofactor guanylyltransferase activity
SynA1524_02709	COG2223	nitrite transmembrane transporter activity
SynA1524_02710	COG0243	molybdopterin cofactor binding
SynA1524_02714	COG0315	cyclic pyranopterin monophosphate synthase activity
SynA1524_02715	COG0303	'Molybdopterin
SynA1524_02718	COG0314	molybdopterin synthase activity
SynA1524_02720	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynA1524_02721	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynA1524_02724	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynA1524_02726	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynA1524_02727	COG1121	(ABC) transporter
SynA1524_02728	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynA1524_02729	COG0523	cobalamin synthesis protein
SynA1524_02733	COG1116	anion transmembrane transporter activity
SynA1524_02734	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SynA1524_02735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SynA1524_02735	COG1116	anion transmembrane transporter activity
SynA1524_02738	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynA1524_02740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynA1524_02743	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynA1524_02744	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1524_02745	COG0170	dolichyl monophosphate biosynthetic process
SynA1524_02747	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynA1524_02748	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynA1524_02751	COG0788	formyltetrahydrofolate deformylase activity
SynA1524_02755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynA1524_02756	COG0443	Heat shock 70 kDa protein
SynA1524_02757	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynA1524_02759	COG0360	Binds together with S18 to 16S ribosomal RNA
SynA1524_02762	COG0137	argininosuccinate synthase activity
SynA1524_02765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynA1524_02768	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynA1524_02769	COG0438	transferase activity, transferring glycosyl groups
SynA1524_02772	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynA1524_02773	COG0497	DNA recombination
SynA1524_02774	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynA1524_02776	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SynA1524_50008	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction