locus-tag	class	description
SynA1560_00001	COG0592	DNA-directed DNA polymerase activity
SynA1560_00003	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynA1560_00005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynA1560_00007	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynA1560_00010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynA1560_00011	COG0552	protein localization to endoplasmic reticulum
SynA1560_00012	COG2208	phosphoserine phosphatase activity
SynA1560_00013	COG0165	Argininosuccinate lyase
SynA1560_00014	COG0724	RNA recognition motif
SynA1560_00015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynA1560_00017	COG2081	HI0933 family
SynA1560_00018	COG1459	type II secretion system
SynA1560_00021	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynA1560_00022	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynA1560_00023	COG0484	heat shock protein binding
SynA1560_00025	COG1162	GTPase activity
SynA1560_00026	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynA1560_00027	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynA1560_00028	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynA1560_00029	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynA1560_00030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynA1560_00031	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynA1560_00032	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynA1560_00033	COG0511	ligase activity, forming carbon-carbon bonds
SynA1560_00034	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynA1560_00049	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynA1560_00050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynA1560_00050	COG0519	Catalyzes the synthesis of GMP from XMP
SynA1560_00054	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00054	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynA1560_00055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynA1560_00057	COG2022	thiamine diphosphate biosynthetic process
SynA1560_00060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynA1560_00061	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynA1560_00062	COG2385	sporulation resulting in formation of a cellular spore
SynA1560_00063	COG1215	transferase activity, transferring glycosyl groups
SynA1560_00064	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynA1560_00067	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynA1560_00068	COG0740	serine-type endopeptidase activity
SynA1560_00069	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynA1560_00070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynA1560_00071	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynA1560_00072	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynA1560_00074	COG0037	tRNA processing
SynA1560_00079	COG0556	nucleotide-excision repair
SynA1560_00080	COG0527	aspartate kinase activity
SynA1560_00082	COG2082	Precorrin-8x methylmutase
SynA1560_00085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynA1560_00087	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynA1560_00089	COG0556	nucleotide-excision repair
SynA1560_00090	COG0556	nucleotide-excision repair
SynA1560_00091	COG0556	nucleotide-excision repair
SynA1560_00092	COG1086	Polysaccharide biosynthesis protein
SynA1560_00093	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynA1560_00094	COG1083	cytidylyl-transferase
SynA1560_00095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SynA1560_00098	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynA1560_00099	COG2089	acid synthase
SynA1560_00102	COG2192	nodulation
SynA1560_00110	COG1091	dTDP-4-dehydrorhamnose reductase activity
SynA1560_00111	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynA1560_00113	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynA1560_00114	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynA1560_00123	COG0859	PFAM glycosyl transferase family 9
SynA1560_00128	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00130	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00140	COG0297	glycogen (starch) synthase activity
SynA1560_00143	COG1216	Glycosyl transferase, family 2
SynA1560_00144	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00151	COG0653	protein targeting
SynA1560_00152	COG1045	serine acetyltransferase
SynA1560_00153	COG1725	Transcriptional regulator
SynA1560_00155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynA1560_00156	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynA1560_00157	COG1372	Participates in initiation and elongation during chromosome replication
SynA1560_00157	COG0187	DNA topoisomerase II activity
SynA1560_00159	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynA1560_00160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynA1560_00162	COG0386	Belongs to the glutathione peroxidase family
SynA1560_00163	COG2239	Acts as a magnesium transporter
SynA1560_00164	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_00166	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynA1560_00167	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynA1560_00173	COG4638	Rieske (2fe-2S)
SynA1560_00174	COG1116	anion transmembrane transporter activity
SynA1560_00175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SynA1560_00178	COG0375	protein maturation
SynA1560_00179	COG0010	Belongs to the arginase family
SynA1560_00182	COG1194	a g-specific adenine glycosylase
SynA1560_00183	COG4413	Urea transporter
SynA1560_00188	COG0802	atpase or kinase
SynA1560_00189	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynA1560_00191	COG0586	Pfam SNARE associated Golgi protein
SynA1560_00192	COG0629	single-stranded DNA binding
SynA1560_00198	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynA1560_00202	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynA1560_00203	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynA1560_00204	COG0515	serine threonine protein kinase
SynA1560_00205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynA1560_00206	COG2255	four-way junction helicase activity
SynA1560_00208	COG1473	amidohydrolase
SynA1560_00212	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynA1560_00216	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynA1560_00217	COG0463	Glycosyl transferase, family 2
SynA1560_00219	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynA1560_00220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynA1560_00221	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynA1560_00222	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_00223	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynA1560_00224	COG1088	dTDP-glucose 4,6-dehydratase activity
SynA1560_00225	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynA1560_00225	COG0662	Cupin 2, conserved barrel domain protein
SynA1560_00226	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynA1560_00228	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1560_00229	COG0571	ribonuclease III activity
SynA1560_00234	COG0058	SHG alpha-glucan phosphorylase activity
SynA1560_00235	COG0475	glutathione-regulated potassium exporter activity
SynA1560_00239	COG0277	FAD linked oxidase domain protein
SynA1560_00241	COG0247	lactate metabolic process
SynA1560_00242	COG0538	isocitrate dehydrogenase activity
SynA1560_00243	COG0463	Glycosyl transferase, family 2
SynA1560_00247	COG5398	heme oxygenase
SynA1560_00250	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00251	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00252	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00253	COG0438	transferase activity, transferring glycosyl groups
SynA1560_00256	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynA1560_00258	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SynA1560_00260	COG1215	transferase activity, transferring glycosyl groups
SynA1560_00262	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SynA1560_00262	COG0517	IMP dehydrogenase activity
SynA1560_00262	COG0617	tRNA 3'-terminal CCA addition
SynA1560_00263	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynA1560_00264	COG0517	IMP dehydrogenase activity
SynA1560_00264	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SynA1560_00267	COG0709	Synthesizes selenophosphate from selenide and ATP
SynA1560_00268	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynA1560_00269	COG0124	histidyl-tRNA synthetase
SynA1560_00270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynA1560_00276	COG4447	cellulose binding
SynA1560_00277	COG1773	rubredoxin
SynA1560_00278	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_00279	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_00280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_00281	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynA1560_00282	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynA1560_00283	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SynA1560_00284	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynA1560_00284	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynA1560_00287	COG0494	nUDIX hydrolase
SynA1560_00288	COG0415	Belongs to the DNA photolyase family
SynA1560_00294	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynA1560_00297	COG0131	Imidazoleglycerol-phosphate dehydratase
SynA1560_00298	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynA1560_00300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynA1560_00304	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynA1560_00305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynA1560_00308	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynA1560_00312	COG1253	flavin adenine dinucleotide binding
SynA1560_00317	COG0343	queuine tRNA-ribosyltransferase activity
SynA1560_00318	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynA1560_00319	COG2205	protein histidine kinase activity
SynA1560_00322	COG0138	bifunctional purine biosynthesis protein purh
SynA1560_00326	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynA1560_00327	COG0004	ammonium transporteR
SynA1560_00328	COG1489	DNA binding
SynA1560_00329	COG0728	peptidoglycan biosynthetic process
SynA1560_00335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynA1560_00336	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynA1560_00337	COG1058	Belongs to the CinA family
SynA1560_00337	COG1546	Belongs to the CinA family
SynA1560_00338	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynA1560_00339	COG0066	3-isopropylmalate dehydratase activity
SynA1560_00346	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynA1560_00347	COG0193	aminoacyl-tRNA hydrolase activity
SynA1560_00350	COG4372	Transposase
SynA1560_00351	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1560_00352	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynA1560_00355	COG0717	Belongs to the dCTP deaminase family
SynA1560_00357	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynA1560_00361	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynA1560_00364	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynA1560_00368	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynA1560_00372	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynA1560_00375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynA1560_00383	COG2094	Belongs to the DNA glycosylase MPG family
SynA1560_00384	COG0540	Belongs to the ATCase OTCase family
SynA1560_00389	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynA1560_00391	COG3536	Protein conserved in bacteria
SynA1560_00392	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynA1560_00395	COG2046	Belongs to the sulfate adenylyltransferase family
SynA1560_00395	COG0529	Catalyzes the synthesis of activated sulfate
SynA1560_00396	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1560_00399	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynA1560_00401	COG0385	Bile acid
SynA1560_00406	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynA1560_00407	COG0436	Aminotransferase
SynA1560_00410	COG1530	ribonuclease E activity
SynA1560_00411	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynA1560_00413	COG0077	Prephenate dehydratase
SynA1560_00414	COG2226	methyltransferase
SynA1560_00415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynA1560_00416	COG0051	transcription antitermination factor activity, RNA binding
SynA1560_00417	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynA1560_00418	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynA1560_00419	COG0049	tRNA binding
SynA1560_00420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynA1560_00423	COG0070	glutamate synthase
SynA1560_00423	COG0069	glutamate synthase activity
SynA1560_00423	COG0067	glutamate synthase
SynA1560_00425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynA1560_00429	COG2885	chlorophyll binding
SynA1560_00430	COG2885	chlorophyll binding
SynA1560_00437	COG0463	Glycosyl transferase, family 2
SynA1560_00441	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynA1560_00443	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynA1560_00446	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynA1560_00447	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynA1560_00448	COG0101	tRNA pseudouridine synthase activity
SynA1560_00449	COG0203	ribosomal protein L17
SynA1560_00450	COG0202	RNA polymerase activity
SynA1560_00451	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynA1560_00452	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynA1560_00453	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynA1560_00454	COG0563	adenylate kinase activity
SynA1560_00455	COG0201	protein transport
SynA1560_00456	COG0200	Binds to the 23S rRNA
SynA1560_00457	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynA1560_00458	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynA1560_00459	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynA1560_00460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynA1560_00461	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynA1560_00462	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynA1560_00463	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynA1560_00464	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynA1560_00465	COG0255	Belongs to the universal ribosomal protein uL29 family
SynA1560_00466	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynA1560_00467	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynA1560_00468	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynA1560_00469	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynA1560_00470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynA1560_00471	COG0089	rRNA binding
SynA1560_00472	COG0088	Forms part of the polypeptide exit tunnel
SynA1560_00473	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynA1560_00476	COG3854	ATPases associated with a variety of cellular activities
SynA1560_00479	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynA1560_00484	COG0287	Prephenate dehydrogenase
SynA1560_00486	COG3001	Fructosamine kinase
SynA1560_00490	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynA1560_00491	COG1606	tRNA processing
SynA1560_00492	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynA1560_00493	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynA1560_00496	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynA1560_00497	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynA1560_00498	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynA1560_00501	COG0772	Belongs to the SEDS family
SynA1560_00502	COG0489	protein tyrosine kinase activity
SynA1560_00503	COG0408	coproporphyrinogen oxidase activity
SynA1560_00512	COG0667	Aldo Keto reductase
SynA1560_00514	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynA1560_00515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynA1560_00516	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynA1560_00516	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynA1560_00517	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynA1560_00552	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1560_00561	COG1070	Carbohydrate kinase
SynA1560_00562	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynA1560_00564	COG0539	negative regulation of cytoplasmic translation
SynA1560_00565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynA1560_00571	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynA1560_00571	COG0758	DNA mediated transformation
SynA1560_00572	COG2890	protein-(glutamine-N5) methyltransferase activity
SynA1560_00573	COG0009	L-threonylcarbamoyladenylate synthase
SynA1560_00576	COG2197	response regulator
SynA1560_00577	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynA1560_00578	COG2894	cell division
SynA1560_00579	COG0850	regulation of cytokinetic process
SynA1560_00580	COG1078	dGTPase activity
SynA1560_00581	COG0793	Belongs to the peptidase S41A family
SynA1560_00582	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynA1560_00583	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynA1560_00595	COG1570	exodeoxyribonuclease VII activity
SynA1560_00597	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1560_00598	COG1643	Atp-dependent helicase
SynA1560_00602	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynA1560_00604	COG0488	(ABC) transporter
SynA1560_00609	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynA1560_00610	COG0569	domain protein
SynA1560_00611	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynA1560_00612	COG3273	potassium ion transport
SynA1560_00612	COG0471	metal ion transport
SynA1560_00613	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynA1560_00614	COG1252	NADH dehydrogenase
SynA1560_00615	COG0175	sulfate reduction
SynA1560_00616	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynA1560_00617	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynA1560_00624	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynA1560_00626	COG0033	Phosphoglucomutase
SynA1560_00635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1560_00639	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynA1560_00640	COG0719	Fe-S assembly protein
SynA1560_00641	COG0396	ATPase activity
SynA1560_00642	COG0719	Fe-S assembly protein
SynA1560_00643	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynA1560_00645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynA1560_00646	COG0235	Class ii aldolase
SynA1560_00648	COG0242	peptide deformylase activity
SynA1560_00651	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynA1560_00653	COG0606	chelatase, subunit chli
SynA1560_00654	COG0537	adenosine 5'-monophosphoramidase activity
SynA1560_00655	COG4178	(ABC) transporter
SynA1560_00659	COG0515	serine threonine protein kinase
SynA1560_00662	COG0439	Biotin carboxylase
SynA1560_00665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1560_00667	COG1196	nuclear chromosome segregation
SynA1560_00671	COG0116	Belongs to the methyltransferase superfamily
SynA1560_00702	COG0492	ferredoxin-NADP+ reductase activity
SynA1560_00703	COG0716	FMN binding
SynA1560_00707	COG0659	secondary active sulfate transmembrane transporter activity
SynA1560_00709	COG0484	heat shock protein binding
SynA1560_00710	COG0113	porphobilinogen synthase activity
SynA1560_00712	COG1193	negative regulation of DNA recombination
SynA1560_00713	COG3842	ATPase activity
SynA1560_00714	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynA1560_00718	COG0488	(ABC) transporter
SynA1560_00720	COG0435	Glutathione S-transferase
SynA1560_00721	COG2988	succinylglutamate desuccinylase activity
SynA1560_00732	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynA1560_00734	COG0195	Participates in both transcription termination and antitermination
SynA1560_00735	COG0779	Required for maturation of 30S ribosomal subunits
SynA1560_00736	COG0641	radical SAM
SynA1560_00740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynA1560_00741	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynA1560_00742	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynA1560_00743	COG0268	Binds directly to 16S ribosomal RNA
SynA1560_00744	COG0084	hydrolase, TatD family'
SynA1560_00745	COG0085	RNA polymerase activity
SynA1560_00746	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynA1560_00747	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynA1560_00749	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynA1560_00757	COG0357	Ribosomal RNA small subunit methyltransferase G
SynA1560_00760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynA1560_00763	COG4106	trans-aconitate 2-methyltransferase activity
SynA1560_00763	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynA1560_00766	COG0156	8-amino-7-oxononanoate synthase activity
SynA1560_00767	COG0385	Bile acid
SynA1560_00768	COG4581	dead DEAH box helicase
SynA1560_00769	COG0114	fumarate hydratase activity
SynA1560_00770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynA1560_00773	COG0347	Belongs to the P(II) protein family
SynA1560_00776	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynA1560_00777	COG1333	cytochrome c biogenesis protein
SynA1560_00778	COG4232	protein-disulfide reductase activity
SynA1560_00779	COG0772	Belongs to the SEDS family
SynA1560_00784	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1560_00785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynA1560_00787	COG0356	it plays a direct role in the translocation of protons across the membrane
SynA1560_00788	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynA1560_00789	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynA1560_00790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynA1560_00791	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynA1560_00792	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynA1560_00793	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynA1560_00795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynA1560_00797	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynA1560_00798	COG3012	SEC-C Motif Domain Protein
SynA1560_00805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynA1560_00805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynA1560_00806	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynA1560_00807	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynA1560_00808	COG1253	flavin adenine dinucleotide binding
SynA1560_00809	COG0006	proline dipeptidase activity
SynA1560_00813	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynA1560_00814	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynA1560_00815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynA1560_00816	COG0459	protein refolding
SynA1560_00817	COG1970	mechanosensitive ion channel activity
SynA1560_00819	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SynA1560_00820	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynA1560_00823	COG0443	Heat shock 70 kDa protein
SynA1560_00830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynA1560_00835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynA1560_00836	COG2264	protein methyltransferase activity
SynA1560_00840	COG2010	Cytochrome c
SynA1560_00841	COG1234	tRNA 3'-trailer cleavage
SynA1560_00842	COG2385	sporulation resulting in formation of a cellular spore
SynA1560_00842	COG2247	cell wall binding repeat
SynA1560_00843	COG0363	glucosamine-6-phosphate deaminase activity
SynA1560_00852	COG0217	transcriptional regulatory protein
SynA1560_00853	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynA1560_00854	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynA1560_00856	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynA1560_00857	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynA1560_00859	COG4251	negative regulation of phosphorylation
SynA1560_00860	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynA1560_00861	COG5002	protein histidine kinase activity
SynA1560_00862	COG0151	Belongs to the GarS family
SynA1560_00864	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynA1560_00866	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynA1560_00867	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynA1560_00868	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynA1560_00870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1560_00875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynA1560_00880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynA1560_00884	COG0284	orotidine-5'-phosphate decarboxylase activity
SynA1560_00886	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynA1560_00889	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynA1560_00890	COG2211	Major facilitator Superfamily
SynA1560_00895	COG0776	regulation of translation
SynA1560_00896	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynA1560_00952	COG1231	oxidoreductase activity
SynA1560_00962	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynA1560_00964	COG1185	polyribonucleotide nucleotidyltransferase activity
SynA1560_00965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynA1560_00966	COG0750	zinc metalloprotease
SynA1560_00967	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynA1560_00969	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1560_00971	COG0706	membrane insertase activity
SynA1560_00973	COG0594	ribonuclease P activity
SynA1560_00974	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynA1560_00977	COG0616	signal peptide processing
SynA1560_00978	COG0697	spore germination
SynA1560_00982	COG1842	Phage shock protein A
SynA1560_00984	COG0436	Aminotransferase
SynA1560_00985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynA1560_00985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynA1560_00986	COG0739	heme binding
SynA1560_00987	COG0745	RESPONSE REGULATOR receiver
SynA1560_00988	COG1136	(ABC) transporter
SynA1560_00989	COG1007	ATP synthesis coupled electron transport
SynA1560_00990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynA1560_00993	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynA1560_01000	COG1845	cytochrome c oxidase, subunit III
SynA1560_01001	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynA1560_01003	COG1612	heme a metabolic process
SynA1560_01004	COG0109	protoheme IX farnesyltransferase activity
SynA1560_01008	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynA1560_01010	COG0459	protein refolding
SynA1560_01012	COG1028	Short-chain dehydrogenase reductase Sdr
SynA1560_01013	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynA1560_01015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynA1560_01016	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynA1560_01017	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynA1560_01018	COG0248	Ppx GppA phosphatase
SynA1560_01025	COG3258	Cytochrome c
SynA1560_01026	COG0723	plastoquinol--plastocyanin reductase activity
SynA1560_01028	COG0805	protein transport
SynA1560_01029	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SynA1560_01030	COG0194	GDP metabolic process
SynA1560_01033	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynA1560_01034	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1560_01036	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SynA1560_01039	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynA1560_01045	COG0335	large ribosomal subunit rRNA binding
SynA1560_01047	COG0024	Methionine aminopeptidase
SynA1560_01048	COG3000	fatty acid hydroxylase
SynA1560_01048	COG0300	oxidoreductase activity
SynA1560_01051	COG0857	belongs to the CobB CobQ family
SynA1560_01054	COG0330	HflC and HflK could
SynA1560_01056	COG1666	GTP binding
SynA1560_01058	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynA1560_01060	COG0277	FAD linked oxidase domain protein
SynA1560_01065	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynA1560_01069	COG0523	cobalamin synthesis protein
SynA1560_01070	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynA1560_01072	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynA1560_01074	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynA1560_01077	COG2095	MarC family integral membrane protein
SynA1560_01079	COG0181	hydroxymethylbilane synthase activity
SynA1560_01093	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_01094	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynA1560_01096	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynA1560_01099	COG0629	single-stranded DNA binding
SynA1560_01100	COG2099	Precorrin-6x reductase
SynA1560_01102	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynA1560_01103	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynA1560_01105	COG0442	prolyl-tRNA aminoacylation
SynA1560_01108	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynA1560_01112	COG0681	Belongs to the peptidase S26 family
SynA1560_01113	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SynA1560_01117	COG0768	penicillin binding
SynA1560_01118	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynA1560_01120	COG0415	Belongs to the DNA photolyase family
SynA1560_01122	COG0233	cytoplasmic translational termination
SynA1560_01123	COG0528	UMP kinase activity
SynA1560_01127	COG2226	methyltransferase
SynA1560_01129	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1560_01130	COG0028	Belongs to the TPP enzyme family
SynA1560_01134	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynA1560_01135	COG1496	oxidoreductase activity
SynA1560_01137	COG0539	negative regulation of cytoplasmic translation
SynA1560_01139	COG3396	Phenylacetate-CoA oxygenase
SynA1560_01140	COG5322	oxidoreductase activity
SynA1560_01141	COG0825	malonyl-CoA metabolic process
SynA1560_01143	COG0302	gtp cyclohydrolase
SynA1560_01144	COG0135	phosphoribosylanthranilate isomerase activity
SynA1560_01145	COG1994	Peptidase M50
SynA1560_01145	COG0517	IMP dehydrogenase activity
SynA1560_01146	COG0095	Lipoate-protein ligase
SynA1560_01147	COG0730	response to heat
SynA1560_01160	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynA1560_01161	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynA1560_01162	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynA1560_01164	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynA1560_01165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynA1560_01166	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynA1560_01167	COG1850	ribulose-bisphosphate carboxylase activity
SynA1560_01168	COG4451	ribulose bisphosphate carboxylase, small
SynA1560_01173	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynA1560_01174	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynA1560_01175	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_01180	COG0251	oxidation-reduction process
SynA1560_01182	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynA1560_01183	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynA1560_01184	COG1132	(ABC) transporter
SynA1560_01185	COG0596	Alpha beta hydrolase
SynA1560_01186	COG0456	acetyltransferase
SynA1560_01189	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynA1560_01190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynA1560_01195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynA1560_01198	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynA1560_01203	COG0530	calcium, potassium:sodium antiporter activity
SynA1560_01205	COG0659	secondary active sulfate transmembrane transporter activity
SynA1560_01206	COG0418	dihydroorotase activity
SynA1560_01209	COG0251	oxidation-reduction process
SynA1560_01215	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynA1560_01215	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynA1560_01220	COG0159	tryptophan synthase activity
SynA1560_01223	COG2010	Cytochrome c
SynA1560_01228	COG3339	Conserved Protein
SynA1560_01229	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_01234	COG1376	ErfK ybiS ycfS ynhG family protein
SynA1560_01238	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynA1560_01238	COG0140	phosphoribosyl-ATP diphosphatase activity
SynA1560_01240	COG1506	peptidase
SynA1560_01240	COG4946	Tricorn protease homolog
SynA1560_01240	COG0823	Involved in the tonB-independent uptake of proteins
SynA1560_01243	COG0542	response to heat
SynA1560_01260	COG3794	PFAM blue (type 1) copper domain protein
SynA1560_01262	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynA1560_01263	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynA1560_01271	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynA1560_01272	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynA1560_01278	COG0339	signal peptide processing
SynA1560_01279	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_01280	COG0083	homoserine kinase activity
SynA1560_01281	COG0837	glucose binding
SynA1560_01283	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynA1560_01287	COG0180	Tryptophanyl-tRNA synthetase
SynA1560_01294	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynA1560_01297	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SynA1560_01302	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1560_01303	COG0351	phosphomethylpyrimidine kinase
SynA1560_01304	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynA1560_01319	COG3781	membrane
SynA1560_01388	COG0590	tRNA wobble adenosine to inosine editing
SynA1560_01399	COG0484	heat shock protein binding
SynA1560_01428	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynA1560_01433	COG0515	serine threonine protein kinase
SynA1560_01435	COG2072	flavoprotein involved in K transport
SynA1560_01440	COG2144	transferase activity, transferring acyl groups
SynA1560_01451	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SynA1560_01464	COG2197	response regulator
SynA1560_01473	COG2124	cytochrome p450
SynA1560_01476	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynA1560_01486	COG0793	Belongs to the peptidase S41A family
SynA1560_01487	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynA1560_01488	COG1573	uracil-dna glycosylase
SynA1560_01490	COG0436	Aminotransferase
SynA1560_01491	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynA1560_01492	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynA1560_01492	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynA1560_01493	COG3639	organic phosphonate transmembrane transporter activity
SynA1560_01500	COG0668	transmembrane transport
SynA1560_01501	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynA1560_01512	COG1126	abc transporter atp-binding protein
SynA1560_01513	COG0765	amino acid transport
SynA1560_01515	COG4597	amino acid ABC transporter
SynA1560_01516	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynA1560_01518	COG0659	secondary active sulfate transmembrane transporter activity
SynA1560_01526	COG0799	negative regulation of ribosome biogenesis
SynA1560_01528	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynA1560_01530	COG1115	amino acid carrier protein
SynA1560_01532	COG1132	(ABC) transporter
SynA1560_01534	COG0149	triose-phosphate isomerase activity
SynA1560_01535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynA1560_01537	COG1429	ligase activity, forming nitrogen-metal bonds
SynA1560_01539	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynA1560_01541	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynA1560_01542	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynA1560_01544	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynA1560_01554	COG2205	protein histidine kinase activity
SynA1560_01560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynA1560_01561	COG1494	fructose-1,6-bisphosphatase
SynA1560_01562	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynA1560_01563	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynA1560_01564	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynA1560_01565	COG0363	glucosamine-6-phosphate deaminase activity
SynA1560_01568	COG0129	dihydroxy-acid dehydratase activity
SynA1560_01570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynA1560_01571	COG1357	PFAM Pentapeptide repeats (8 copies)
SynA1560_01581	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynA1560_01582	COG0047	phosphoribosylformylglycinamidine synthase activity
SynA1560_01583	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynA1560_01590	COG0191	fructose-bisphosphate aldolase activity
SynA1560_01592	COG3588	fructose-bisphosphate aldolase
SynA1560_01594	COG0673	inositol 2-dehydrogenase activity
SynA1560_01596	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynA1560_01598	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynA1560_01600	COG3954	Phosphoribulokinase
SynA1560_01601	COG0473	3-isopropylmalate dehydrogenase activity
SynA1560_01602	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynA1560_01603	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynA1560_01606	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynA1560_01609	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynA1560_01610	COG2197	response regulator
SynA1560_01612	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynA1560_01615	COG0516	GMP reductase activity
SynA1560_01615	COG0517	IMP dehydrogenase activity
SynA1560_01623	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1560_01625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynA1560_01662	COG1201	RNA secondary structure unwinding
SynA1560_01666	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynA1560_01669	COG1793	dna ligase
SynA1560_01671	COG1793	dna ligase
SynA1560_01671	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SynA1560_01679	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynA1560_01680	COG1175	transmembrane transport
SynA1560_01681	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynA1560_01694	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynA1560_01699	COG0740	serine-type endopeptidase activity
SynA1560_01700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1560_01701	COG1136	(ABC) transporter
SynA1560_01701	COG0577	efflux transmembrane transporter activity
SynA1560_01702	COG0469	pyruvate kinase activity
SynA1560_01706	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynA1560_01707	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynA1560_01712	COG3842	ATPase activity
SynA1560_01715	COG1653	transport
SynA1560_01716	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynA1560_01717	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynA1560_01718	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynA1560_01719	COG0326	Molecular chaperone. Has ATPase activity
SynA1560_01721	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynA1560_01722	COG0483	inositol monophosphate 1-phosphatase activity
SynA1560_01725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynA1560_01726	COG0581	inorganic phosphate transmembrane transporter activity
SynA1560_01727	COG0573	inorganic phosphate transmembrane transporter activity
SynA1560_01728	COG0443	Heat shock 70 kDa protein
SynA1560_01729	COG0484	heat shock protein binding
SynA1560_01731	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynA1560_01732	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynA1560_01733	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynA1560_01734	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynA1560_01734	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynA1560_01735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynA1560_01736	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynA1560_01742	COG0166	Belongs to the GPI family
SynA1560_01743	COG0495	leucyl-tRNA aminoacylation
SynA1560_01745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynA1560_01746	COG1104	cysteine desulfurase activity
SynA1560_01751	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynA1560_01752	COG0322	excinuclease ABC activity
SynA1560_01754	COG3046	protein related to deoxyribodipyrimidine photolyase
SynA1560_01755	COG1981	membrane
SynA1560_01759	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynA1560_01760	COG1410	methionine synthase
SynA1560_01760	COG0646	methionine synthase
SynA1560_01765	COG2385	sporulation resulting in formation of a cellular spore
SynA1560_01767	COG1191	sigma factor activity
SynA1560_01774	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynA1560_01775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynA1560_01775	COG0072	phenylalanine-tRNA ligase activity
SynA1560_01776	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynA1560_01777	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynA1560_01778	COG0557	exoribonuclease II activity
SynA1560_01780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynA1560_01785	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
SynA1560_01786	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynA1560_01790	COG0450	alkyl hydroperoxide reductase
SynA1560_01791	COG1615	UPF0182 protein
SynA1560_01792	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1560_01793	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynA1560_01796	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynA1560_01797	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynA1560_01797	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynA1560_01802	COG2119	membrane
SynA1560_01804	COG0557	exoribonuclease II activity
SynA1560_01805	COG0163	prenyltransferase activity
SynA1560_01808	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynA1560_01809	COG0312	modulator of DNA gyrase
SynA1560_01811	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynA1560_01812	COG0513	Belongs to the DEAD box helicase family
SynA1560_01816	COG0861	Integral membrane protein TerC family
SynA1560_01843	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynA1560_01849	COG0745	RESPONSE REGULATOR receiver
SynA1560_01851	COG0596	Alpha beta hydrolase
SynA1560_01852	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynA1560_01853	COG0271	Belongs to the BolA IbaG family
SynA1560_01856	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynA1560_01868	COG0735	belongs to the Fur family
SynA1560_01870	COG1799	cell septum assembly
SynA1560_01876	COG0420	3'-5' exonuclease activity
SynA1560_01885	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynA1560_01902	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynA1560_01907	COG1217	gtp-binding protein TYPA
SynA1560_01908	COG0826	peptidase U32
SynA1560_01910	COG0644	oxidoreductase
SynA1560_01911	COG0751	glycine-tRNA ligase activity
SynA1560_01912	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynA1560_01913	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynA1560_01914	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynA1560_01916	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynA1560_01917	COG0052	Belongs to the universal ribosomal protein uS2 family
SynA1560_01918	COG1216	Glycosyl transferase, family 2
SynA1560_01924	COG0612	Peptidase, M16
SynA1560_01928	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynA1560_01929	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynA1560_01932	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynA1560_01934	COG0174	glutamine synthetase
SynA1560_01937	COG2226	methyltransferase
SynA1560_01942	COG0515	serine threonine protein kinase
SynA1560_01943	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynA1560_01945	COG0628	permease
SynA1560_01950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynA1560_01951	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynA1560_01952	COG0022	dehydrogenase e1 component
SynA1560_01952	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynA1560_01955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynA1560_01956	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynA1560_01957	COG0572	uridine kinase
SynA1560_01966	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynA1560_01973	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynA1560_01981	COG0358	DNA primase activity
SynA1560_01987	COG0632	four-way junction helicase activity
SynA1560_01988	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynA1560_01990	COG0587	DNA-directed DNA polymerase activity
SynA1560_01991	COG0154	amidase activity
SynA1560_01993	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynA1560_01994	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynA1560_01996	COG0505	Belongs to the CarA family
SynA1560_01997	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynA1560_01998	COG1132	(ABC) transporter
SynA1560_02000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynA1560_02004	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1560_02007	COG2176	DNA-directed DNA polymerase activity
SynA1560_02008	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynA1560_02012	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynA1560_02016	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynA1560_02017	COG0142	geranyltranstransferase activity
SynA1560_02018	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynA1560_02021	COG2045	Belongs to the ComB family
SynA1560_02022	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynA1560_02023	COG1840	ABC-type Fe3 transport system, periplasmic component
SynA1560_02024	COG3128	pkhd-type hydroxylase
SynA1560_02026	COG3659	wide pore channel activity
SynA1560_02028	COG3659	wide pore channel activity
SynA1560_02032	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynA1560_02039	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynA1560_02041	COG4178	(ABC) transporter
SynA1560_02042	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynA1560_02044	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynA1560_02046	COG0297	glycogen (starch) synthase activity
SynA1560_02047	COG1376	ErfK ybiS ycfS ynhG family protein
SynA1560_02048	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SynA1560_02049	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynA1560_02050	COG0681	Belongs to the peptidase S26 family
SynA1560_02053	COG0583	DNA-binding transcription factor activity
SynA1560_02055	COG3239	Fatty acid desaturase
SynA1560_02061	COG1231	oxidoreductase activity
SynA1560_02064	COG2132	Multicopper oxidase
SynA1560_02067	COG3961	Belongs to the TPP enzyme family
SynA1560_02099	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynA1560_02100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynA1560_02101	COG1121	(ABC) transporter
SynA1560_02104	COG0701	Predicted permease
SynA1560_02105	COG2010	Cytochrome c
SynA1560_02108	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynA1560_02110	COG1121	(ABC) transporter
SynA1560_02130	COG0583	DNA-binding transcription factor activity
SynA1560_02135	COG2032	superoxide dismutase activity
SynA1560_02157	COG0300	oxidoreductase activity
SynA1560_02170	COG2720	vancomycin resistance protein
SynA1560_02175	COG1191	sigma factor activity
SynA1560_02176	COG1836	PFAM Integral membrane protein DUF92
SynA1560_02181	COG1122	ATPase activity
SynA1560_02182	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynA1560_02188	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynA1560_02189	COG4106	trans-aconitate 2-methyltransferase activity
SynA1560_02190	COG0668	transmembrane transport
SynA1560_02191	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SynA1560_02211	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynA1560_02239	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynA1560_02240	COG1074	ATP-dependent DNA helicase activity
SynA1560_02241	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynA1560_02244	COG0513	Belongs to the DEAD box helicase family
SynA1560_02246	COG0724	RNA recognition motif
SynA1560_02248	COG1132	(ABC) transporter
SynA1560_02249	COG0589	response to stress
SynA1560_02249	COG0475	glutathione-regulated potassium exporter activity
SynA1560_02257	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynA1560_02258	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynA1560_02261	COG1054	Belongs to the UPF0176 family
SynA1560_02262	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynA1560_02263	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynA1560_02264	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynA1560_02265	COG0019	diaminopimelate decarboxylase activity
SynA1560_02267	COG0542	response to heat
SynA1560_02268	COG0371	Dehydrogenase
SynA1560_02269	COG2267	carboxylic ester hydrolase activity
SynA1560_02271	COG0575	Belongs to the CDS family
SynA1560_02272	COG1982	Orn Lys Arg decarboxylase major
SynA1560_02273	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynA1560_02275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_02276	COG0745	RESPONSE REGULATOR receiver
SynA1560_02277	COG5002	protein histidine kinase activity
SynA1560_02278	COG1187	pseudouridine synthase activity
SynA1560_02280	COG1640	4-alpha-glucanotransferase
SynA1560_02281	COG0702	epimerase
SynA1560_02283	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynA1560_02287	COG0308	aminopeptidase N
SynA1560_02290	COG2205	protein histidine kinase activity
SynA1560_02293	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SynA1560_02294	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynA1560_02295	COG3409	Peptidoglycan-binding domain 1 protein
SynA1560_02295	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynA1560_02296	COG1797	cobyrinic acid a,c-diamide synthase activity
SynA1560_02297	COG1254	Belongs to the acylphosphatase family
SynA1560_02301	COG0142	geranyltranstransferase activity
SynA1560_02302	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynA1560_02303	COG1480	7TM receptor with intracellular HD hydrolase
SynA1560_02304	COG0564	pseudouridine synthase activity
SynA1560_02308	COG0011	TIGRFAM Protein of
SynA1560_02312	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynA1560_02316	COG0395	ABC-type sugar transport system, permease component
SynA1560_02317	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynA1560_02318	COG1543	Belongs to the glycosyl hydrolase 57 family
SynA1560_02322	COG0644	oxidoreductase
SynA1560_02323	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynA1560_02325	COG0516	GMP reductase activity
SynA1560_02326	COG3118	belongs to the thioredoxin family
SynA1560_02327	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynA1560_02329	COG2010	Cytochrome c
SynA1560_02333	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynA1560_02334	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynA1560_02337	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynA1560_02339	COG2166	iron-sulfur cluster assembly
SynA1560_02340	COG0460	homoserine dehydrogenase
SynA1560_02342	COG0747	negative chemotaxis
SynA1560_02343	COG0601	transmembrane transport
SynA1560_02353	COG0012	GTP binding
SynA1560_02354	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynA1560_02355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynA1560_02355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynA1560_02356	COG0215	cysteine-tRNA ligase activity
SynA1560_02359	COG0733	neurotransmitter:sodium symporter activity
SynA1560_02360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynA1560_02361	COG3411	Ferredoxin
SynA1560_02370	COG0492	ferredoxin-NADP+ reductase activity
SynA1560_02371	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynA1560_02373	COG1187	pseudouridine synthase activity
SynA1560_02374	COG2226	methyltransferase
SynA1560_02376	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynA1560_02380	COG0440	acetolactate synthase activity
SynA1560_02381	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynA1560_02387	COG0424	maF-like protein
SynA1560_02391	COG2274	protein secretion by the type I secretion system
SynA1560_02394	COG1492	cobalamin metabolic process
SynA1560_02399	COG0432	Pfam Uncharacterised protein family UPF0047
SynA1560_02416	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SynA1560_02426	COG2770	Histidine kinase
SynA1560_02426	COG2208	phosphoserine phosphatase activity
SynA1560_02446	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynA1560_02450	COG1647	Serine aminopeptidase, S33
SynA1560_02457	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynA1560_02458	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynA1560_02460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynA1560_02460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynA1560_02470	COG3119	arylsulfatase activity
SynA1560_02472	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynA1560_02481	COG0745	RESPONSE REGULATOR receiver
SynA1560_02482	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynA1560_02485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynA1560_02486	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynA1560_02488	COG0196	riboflavin kinase activity
SynA1560_02490	COG0352	thiamine-phosphate diphosphorylase activity
SynA1560_02495	COG1691	(AIR) carboxylase
SynA1560_02497	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynA1560_02498	COG0336	Belongs to the RNA methyltransferase TrmD family
SynA1560_02500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynA1560_02502	COG0670	Belongs to the BI1 family
SynA1560_02503	COG1702	phosphate starvation-inducible protein PhoH
SynA1560_02504	COG0228	four-way junction DNA binding
SynA1560_02505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynA1560_02507	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynA1560_02508	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynA1560_02509	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_02510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynA1560_02510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynA1560_02511	COG0482	sulfurtransferase activity
SynA1560_02512	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynA1560_02518	COG1007	ATP synthesis coupled electron transport
SynA1560_02524	COG0134	indole-3-glycerol-phosphate synthase activity
SynA1560_02525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynA1560_02526	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynA1560_02529	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynA1560_02536	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynA1560_02537	COG0285	dihydrofolate synthase activity
SynA1560_02544	COG4948	Mandelate Racemase Muconate Lactonizing
SynA1560_02545	COG2066	Belongs to the glutaminase family
SynA1560_02545	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
SynA1560_02546	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynA1560_02547	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynA1560_02550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynA1560_02551	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynA1560_02552	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynA1560_02553	COG4956	integral membrane protein (PIN domain superfamily)
SynA1560_02554	COG0740	serine-type endopeptidase activity
SynA1560_02555	COG0740	serine-type endopeptidase activity
SynA1560_02556	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynA1560_02558	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynA1560_02567	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynA1560_02574	COG0752	glycyl-tRNA synthetase alpha subunit
SynA1560_02576	COG2226	methyltransferase
SynA1560_02578	COG0107	imidazoleglycerol-phosphate synthase activity
SynA1560_02580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynA1560_02581	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynA1560_02582	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynA1560_02582	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynA1560_02585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynA1560_02587	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SynA1560_02588	COG4999	Histidine kinase
SynA1560_02588	COG3850	Histidine kinase
SynA1560_02588	COG3437	response regulator, receiver
SynA1560_02588	COG2205	protein histidine kinase activity
SynA1560_02590	COG2205	protein histidine kinase activity
SynA1560_02595	COG0745	RESPONSE REGULATOR receiver
SynA1560_02603	COG0481	GTPase activity
SynA1560_02606	COG0579	oxidoreductase
SynA1560_02607	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynA1560_02609	COG1104	cysteine desulfurase activity
SynA1560_02610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynA1560_02618	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynA1560_02620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynA1560_02621	COG0531	amino acid
SynA1560_02622	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynA1560_02624	COG1022	Amp-dependent synthetase and ligase
SynA1560_02625	COG0321	lipoyl(octanoyl) transferase activity
SynA1560_02626	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynA1560_02627	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynA1560_02628	COG1381	Involved in DNA repair and RecF pathway recombination
SynA1560_02630	COG0438	transferase activity, transferring glycosyl groups
SynA1560_02631	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynA1560_02632	COG1799	cell septum assembly
SynA1560_02635	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynA1560_02636	COG1160	GTP binding
SynA1560_02637	COG1376	ErfK ybiS ycfS ynhG family protein
SynA1560_02640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynA1560_02643	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynA1560_02647	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynA1560_02652	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SynA1560_02653	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynA1560_02655	COG1012	belongs to the aldehyde dehydrogenase family
SynA1560_02656	COG1388	LysM domain
SynA1560_02656	COG3942	CHAP domain
SynA1560_02660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynA1560_02661	COG0235	Class ii aldolase
SynA1560_02662	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynA1560_02669	COG0483	inositol monophosphate 1-phosphatase activity
SynA1560_02672	COG1968	undecaprenyl-diphosphatase activity
SynA1560_02674	COG1555	photosystem II stabilization
SynA1560_02675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynA1560_02676	COG4243	Vitamin k epoxide reductase
SynA1560_02677	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynA1560_02680	COG1032	radical SAM domain protein
SynA1560_02686	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynA1560_02690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynA1560_02691	COG1472	Belongs to the glycosyl hydrolase 3 family
SynA1560_02692	COG0457	Tetratricopeptide repeat
SynA1560_02692	COG0463	Glycosyl transferase, family 2
SynA1560_02693	COG1587	Uroporphyrinogen-III synthase
SynA1560_02696	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynA1560_02697	COG0316	Belongs to the HesB IscA family
SynA1560_02700	COG1090	epimerase
SynA1560_02701	COG3263	regulation of cellular component size
SynA1560_02704	COG0484	heat shock protein binding
SynA1560_02705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynA1560_02707	COG3659	wide pore channel activity
SynA1560_02710	COG1216	Glycosyl transferase, family 2
SynA1560_02716	COG1122	ATPase activity
SynA1560_02719	COG0745	RESPONSE REGULATOR receiver
SynA1560_02721	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynA1560_02722	COG2217	Heavy metal translocating P-type atpase
SynA1560_02723	COG3063	Type IV pilus biogenesis stability protein PilW
SynA1560_02724	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynA1560_02726	COG0416	fatty acid biosynthetic process
SynA1560_02727	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynA1560_02728	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynA1560_02731	COG1214	PFAM Peptidase M22, glycoprotease
SynA1560_02733	COG0617	tRNA 3'-terminal CCA addition
SynA1560_02745	COG2894	cell division
SynA1560_02747	COG1562	ergosterol biosynthetic process
SynA1560_02750	COG2205	protein histidine kinase activity
SynA1560_02750	COG2198	Histidine kinase
SynA1560_02750	COG0784	Response regulator, receiver
SynA1560_02751	COG0493	'glutamate synthase
SynA1560_02751	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynA1560_02754	COG0583	DNA-binding transcription factor activity
SynA1560_02756	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynA1560_02758	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_02761	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynA1560_02763	COG2197	response regulator
SynA1560_02766	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynA1560_02767	COG0713	ATP synthesis coupled electron transport
SynA1560_02768	COG0839	Belongs to the complex I subunit 6 family
SynA1560_02769	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynA1560_02770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynA1560_02771	COG0372	Belongs to the citrate synthase family
SynA1560_02772	COG2062	phosphohistidine phosphatase, SixA
SynA1560_02775	COG1420	regulation of RNA biosynthetic process
SynA1560_02777	COG0133	tryptophan synthase activity
SynA1560_02778	COG2226	methyltransferase
SynA1560_02779	COG0023	Translation Initiation Factor
SynA1560_02780	COG0529	Catalyzes the synthesis of activated sulfate
SynA1560_02781	COG0628	permease
SynA1560_02783	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynA1560_02785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynA1560_02786	COG0564	pseudouridine synthase activity
SynA1560_02787	COG0745	RESPONSE REGULATOR receiver
SynA1560_02792	COG0275	rRNA processing
SynA1560_02793	COG0649	NAD binding
SynA1560_02795	COG0824	Thioesterase
SynA1560_02800	COG1575	Belongs to the MenA family. Type 1 subfamily
SynA1560_02803	COG0189	ligase activity
SynA1560_02804	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynA1560_02806	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynA1560_02808	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynA1560_02809	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynA1560_02810	COG0512	Glutamine amidotransferase of anthranilate synthase
SynA1560_02823	COG0252	asparaginase activity
SynA1560_02825	COG0018	arginyl-trna synthetase
SynA1560_02832	COG0157	Belongs to the NadC ModD family
SynA1560_02834	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynA1560_02836	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynA1560_02837	COG4172	Belongs to the ABC transporter superfamily
SynA1560_02840	COG0564	pseudouridine synthase activity
SynA1560_02842	COG0589	response to stress
SynA1560_02843	COG0126	phosphoglycerate kinase activity
SynA1560_02848	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynA1560_02849	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynA1560_02855	COG0167	dihydroorotate dehydrogenase activity
SynA1560_02856	COG0328	RNA-DNA hybrid ribonuclease activity
SynA1560_02858	COG0222	ribosome binding
SynA1560_02859	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynA1560_02860	COG0081	regulation of translation
SynA1560_02861	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynA1560_02862	COG0250	Participates in transcription elongation, termination and antitermination
SynA1560_02863	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynA1560_02864	COG0542	response to heat
SynA1560_02865	COG0346	lactoylglutathione lyase activity
SynA1560_02867	COG0148	phosphopyruvate hydratase activity
SynA1560_02868	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynA1560_02871	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynA1560_02872	COG0237	dephospho-CoA kinase activity
SynA1560_02875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynA1560_02877	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynA1560_02877	COG2022	thiamine diphosphate biosynthetic process
SynA1560_02878	COG0105	UTP biosynthetic process
SynA1560_02879	COG1166	arginine decarboxylase activity
SynA1560_02894	COG2274	protein secretion by the type I secretion system
SynA1560_02900	COG0668	transmembrane transport
SynA1560_02904	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynA1560_02906	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynA1560_02911	COG0426	domain, Protein
SynA1560_02911	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynA1560_02912	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynA1560_02912	COG0426	domain, Protein
SynA1560_02913	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynA1560_02913	COG1773	rubredoxin
SynA1560_02915	COG1741	Belongs to the pirin family
SynA1560_02919	COG0509	glycine decarboxylation via glycine cleavage system
SynA1560_02920	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynA1560_02924	COG0359	binds to the 23S rRNA
SynA1560_02925	COG1372	Participates in initiation and elongation during chromosome replication
SynA1560_02925	COG0305	Participates in initiation and elongation during chromosome replication
SynA1560_02925	COG1372	Participates in initiation and elongation during chromosome replication
SynA1560_02925	COG0305	Participates in initiation and elongation during chromosome replication
SynA1560_02932	COG0445	tRNA wobble uridine modification
SynA1560_02940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynA1560_02943	COG0398	Pfam SNARE associated Golgi protein
SynA1560_02947	COG0668	transmembrane transport
SynA1560_02951	COG0525	valine-tRNA ligase activity
SynA1560_02953	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynA1560_02953	COG3264	Mechanosensitive ion channel
SynA1560_02957	COG1028	Short-chain dehydrogenase reductase Sdr
SynA1560_02981	COG3956	TIGRFAM MazG family protein
SynA1560_02984	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynA1560_02986	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynA1560_02987	COG0010	Belongs to the arginase family
SynA1560_02991	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynA1560_02992	COG2208	phosphoserine phosphatase activity
SynA1560_02992	COG2770	Histidine kinase
SynA1560_03001	COG2208	phosphoserine phosphatase activity
SynA1560_03001	COG2770	Histidine kinase
SynA1560_03003	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynA1560_03004	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_03005	COG0783	Belongs to the Dps family
SynA1560_03006	COG0504	CTP synthase activity
SynA1560_03007	COG0602	queuosine metabolic process
SynA1560_03008	COG4942	peptidase
SynA1560_03009	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SynA1560_03012	COG4574	serine-type endopeptidase inhibitor activity
SynA1560_03013	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynA1560_03017	COG3769	mannosylglycerate metabolic process
SynA1560_03018	COG0366	Alpha amylase catalytic
SynA1560_03026	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynA1560_03027	COG0830	nickel cation binding
SynA1560_03028	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynA1560_03030	COG0829	nickel cation binding
SynA1560_03031	COG0831	urea catabolic process
SynA1560_03032	COG0832	Belongs to the urease beta subunit family
SynA1560_03033	COG0804	urea catabolic process
SynA1560_03034	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynA1560_03039	COG0367	asparagine synthase
SynA1560_03040	COG0540	Belongs to the ATCase OTCase family
SynA1560_03044	COG2308	Evidence 4 Homologs of previously reported genes of
SynA1560_03048	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynA1560_03050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynA1560_03051	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynA1560_03052	COG0746	molybdenum cofactor guanylyltransferase activity
SynA1560_03053	COG2223	nitrite transmembrane transporter activity
SynA1560_03054	COG2223	nitrite transmembrane transporter activity
SynA1560_03055	COG0243	molybdopterin cofactor binding
SynA1560_03060	COG0315	cyclic pyranopterin monophosphate synthase activity
SynA1560_03061	COG0303	'Molybdopterin
SynA1560_03064	COG0314	molybdopterin synthase activity
SynA1560_03066	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynA1560_03067	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynA1560_03069	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynA1560_03071	COG2116	formate transmembrane transporter activity
SynA1560_03073	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynA1560_03075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynA1560_03078	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynA1560_03079	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynA1560_03080	COG0170	dolichyl monophosphate biosynthetic process
SynA1560_03082	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynA1560_03083	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynA1560_03086	COG0788	formyltetrahydrofolate deformylase activity
SynA1560_03091	COG0443	Heat shock 70 kDa protein
SynA1560_03092	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynA1560_03094	COG0360	Binds together with S18 to 16S ribosomal RNA
SynA1560_03096	COG0137	argininosuccinate synthase activity
SynA1560_03099	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynA1560_03103	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynA1560_03104	COG0438	transferase activity, transferring glycosyl groups
SynA1560_03106	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynA1560_03107	COG0497	DNA recombination
SynA1560_03108	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynA1560_03110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SynA1560_50007	COG3263	regulation of cellular component size