locus-tag	class	description
SynBIOSU31_00001	COG0592	DNA-directed DNA polymerase activity
SynBIOSU31_00003	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynBIOSU31_00005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynBIOSU31_00007	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynBIOSU31_00010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynBIOSU31_00011	COG0552	protein localization to endoplasmic reticulum
SynBIOSU31_00013	COG2208	phosphoserine phosphatase activity
SynBIOSU31_00014	COG0165	Argininosuccinate lyase
SynBIOSU31_00015	COG0724	RNA recognition motif
SynBIOSU31_00016	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynBIOSU31_00018	COG2081	HI0933 family
SynBIOSU31_00019	COG1459	type II secretion system
SynBIOSU31_00021	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynBIOSU31_00022	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynBIOSU31_00023	COG0484	heat shock protein binding
SynBIOSU31_00025	COG1162	GTPase activity
SynBIOSU31_00026	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynBIOSU31_00027	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynBIOSU31_00028	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynBIOSU31_00030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynBIOSU31_00031	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynBIOSU31_00032	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBIOSU31_00034	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynBIOSU31_00035	COG0511	ligase activity, forming carbon-carbon bonds
SynBIOSU31_00036	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynBIOSU31_00048	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynBIOSU31_00049	COG0519	Catalyzes the synthesis of GMP from XMP
SynBIOSU31_00049	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynBIOSU31_00059	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SynBIOSU31_00063	COG0768	penicillin binding
SynBIOSU31_00064	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynBIOSU31_00067	COG2022	thiamine diphosphate biosynthetic process
SynBIOSU31_00070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynBIOSU31_00071	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynBIOSU31_00074	COG1215	transferase activity, transferring glycosyl groups
SynBIOSU31_00075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynBIOSU31_00077	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynBIOSU31_00078	COG0740	serine-type endopeptidase activity
SynBIOSU31_00079	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynBIOSU31_00080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynBIOSU31_00081	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynBIOSU31_00082	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynBIOSU31_00084	COG0037	tRNA processing
SynBIOSU31_00086	COG0556	nucleotide-excision repair
SynBIOSU31_00087	COG0527	aspartate kinase activity
SynBIOSU31_00089	COG2082	Precorrin-8x methylmutase
SynBIOSU31_00091	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBIOSU31_00093	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynBIOSU31_00096	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00097	COG0653	protein targeting
SynBIOSU31_00098	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBIOSU31_00102	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynBIOSU31_00113	COG1088	dTDP-glucose 4,6-dehydratase activity
SynBIOSU31_00116	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00116	COG1216	Glycosyl transferase, family 2
SynBIOSU31_00117	COG1215	transferase activity, transferring glycosyl groups
SynBIOSU31_00121	COG2192	nodulation
SynBIOSU31_00122	COG1045	serine acetyltransferase
SynBIOSU31_00123	COG1725	Transcriptional regulator
SynBIOSU31_00126	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynBIOSU31_00127	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynBIOSU31_00128	COG1372	Participates in initiation and elongation during chromosome replication
SynBIOSU31_00128	COG0187	DNA topoisomerase II activity
SynBIOSU31_00130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynBIOSU31_00131	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynBIOSU31_00132	COG0386	Belongs to the glutathione peroxidase family
SynBIOSU31_00135	COG2239	Acts as a magnesium transporter
SynBIOSU31_00136	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_00137	COG2267	carboxylic ester hydrolase activity
SynBIOSU31_00144	COG0802	atpase or kinase
SynBIOSU31_00145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynBIOSU31_00146	COG0586	Pfam SNARE associated Golgi protein
SynBIOSU31_00147	COG0629	single-stranded DNA binding
SynBIOSU31_00149	COG1792	Involved in formation and maintenance of cell shape
SynBIOSU31_00152	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_00153	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynBIOSU31_00156	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynBIOSU31_00157	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBIOSU31_00158	COG0515	serine threonine protein kinase
SynBIOSU31_00158	COG1357	PFAM Pentapeptide repeats (8 copies)
SynBIOSU31_00159	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynBIOSU31_00160	COG2255	four-way junction helicase activity
SynBIOSU31_00162	COG1473	amidohydrolase
SynBIOSU31_00165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynBIOSU31_00170	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBIOSU31_00170	COG0493	'glutamate synthase
SynBIOSU31_00174	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBIOSU31_00177	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynBIOSU31_00178	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynBIOSU31_00179	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynBIOSU31_00180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_00181	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynBIOSU31_00182	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynBIOSU31_00182	COG0662	Cupin 2, conserved barrel domain protein
SynBIOSU31_00183	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynBIOSU31_00185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_00186	COG0571	ribonuclease III activity
SynBIOSU31_00198	COG0058	SHG alpha-glucan phosphorylase activity
SynBIOSU31_00200	COG0475	glutathione-regulated potassium exporter activity
SynBIOSU31_00205	COG1304	FMN binding
SynBIOSU31_00206	COG0277	FAD linked oxidase domain protein
SynBIOSU31_00210	COG0538	isocitrate dehydrogenase activity
SynBIOSU31_00211	COG0463	Glycosyl transferase, family 2
SynBIOSU31_00214	COG5398	heme oxygenase
SynBIOSU31_00216	COG1132	(ABC) transporter
SynBIOSU31_00217	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00218	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00219	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00220	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00222	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynBIOSU31_00224	COG0617	tRNA 3'-terminal CCA addition
SynBIOSU31_00225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynBIOSU31_00232	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynBIOSU31_00233	COG0124	histidyl-tRNA synthetase
SynBIOSU31_00245	COG0124	histidyl-tRNA synthetase
SynBIOSU31_00248	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBIOSU31_00252	COG1132	(ABC) transporter
SynBIOSU31_00260	COG2089	acid synthase
SynBIOSU31_00264	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynBIOSU31_00265	COG1086	Polysaccharide biosynthesis protein
SynBIOSU31_00268	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynBIOSU31_00269	COG1083	cytidylyl-transferase
SynBIOSU31_00271	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynBIOSU31_00273	COG0673	inositol 2-dehydrogenase activity
SynBIOSU31_00274	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SynBIOSU31_00276	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBIOSU31_00285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SynBIOSU31_00294	COG4447	cellulose binding
SynBIOSU31_00295	COG1773	rubredoxin
SynBIOSU31_00296	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_00297	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_00298	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_00299	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynBIOSU31_00300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynBIOSU31_00302	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBIOSU31_00302	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBIOSU31_00303	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SynBIOSU31_00304	COG1136	(ABC) transporter
SynBIOSU31_00305	COG0494	nUDIX hydrolase
SynBIOSU31_00306	COG0415	Belongs to the DNA photolyase family
SynBIOSU31_00312	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynBIOSU31_00313	COG0131	Imidazoleglycerol-phosphate dehydratase
SynBIOSU31_00314	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynBIOSU31_00318	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynBIOSU31_00322	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynBIOSU31_00323	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynBIOSU31_00325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynBIOSU31_00326	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynBIOSU31_00327	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_00328	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBIOSU31_00331	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynBIOSU31_00334	COG1253	flavin adenine dinucleotide binding
SynBIOSU31_00335	COG0673	inositol 2-dehydrogenase activity
SynBIOSU31_00339	COG0343	queuine tRNA-ribosyltransferase activity
SynBIOSU31_00340	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynBIOSU31_00345	COG0138	bifunctional purine biosynthesis protein purh
SynBIOSU31_00357	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynBIOSU31_00358	COG0004	ammonium transporteR
SynBIOSU31_00359	COG1489	DNA binding
SynBIOSU31_00360	COG0728	peptidoglycan biosynthetic process
SynBIOSU31_00366	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynBIOSU31_00367	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynBIOSU31_00368	COG1058	Belongs to the CinA family
SynBIOSU31_00368	COG1546	Belongs to the CinA family
SynBIOSU31_00369	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynBIOSU31_00370	COG0066	3-isopropylmalate dehydratase activity
SynBIOSU31_00377	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynBIOSU31_00378	COG0193	aminoacyl-tRNA hydrolase activity
SynBIOSU31_00381	COG4372	Transposase
SynBIOSU31_00382	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_00383	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynBIOSU31_00386	COG0717	Belongs to the dCTP deaminase family
SynBIOSU31_00388	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynBIOSU31_00392	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynBIOSU31_00395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynBIOSU31_00400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynBIOSU31_00404	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynBIOSU31_00407	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynBIOSU31_00409	COG2094	Belongs to the DNA glycosylase MPG family
SynBIOSU31_00410	COG0540	Belongs to the ATCase OTCase family
SynBIOSU31_00417	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBIOSU31_00419	COG3536	Protein conserved in bacteria
SynBIOSU31_00420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynBIOSU31_00423	COG0529	Catalyzes the synthesis of activated sulfate
SynBIOSU31_00423	COG2046	Belongs to the sulfate adenylyltransferase family
SynBIOSU31_00424	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_00427	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynBIOSU31_00429	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynBIOSU31_00430	COG2226	methyltransferase
SynBIOSU31_00432	COG4176	ABC-type proline glycine betaine transport system permease component
SynBIOSU31_00433	COG2113	Glycine betaine
SynBIOSU31_00437	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynBIOSU31_00438	COG0436	Aminotransferase
SynBIOSU31_00440	COG1530	ribonuclease E activity
SynBIOSU31_00441	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynBIOSU31_00443	COG0077	Prephenate dehydratase
SynBIOSU31_00443	COG1605	Chorismate mutase
SynBIOSU31_00444	COG2226	methyltransferase
SynBIOSU31_00445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynBIOSU31_00446	COG0051	transcription antitermination factor activity, RNA binding
SynBIOSU31_00447	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynBIOSU31_00448	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynBIOSU31_00449	COG0049	tRNA binding
SynBIOSU31_00450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynBIOSU31_00453	COG0070	glutamate synthase
SynBIOSU31_00453	COG0069	glutamate synthase activity
SynBIOSU31_00453	COG0067	glutamate synthase
SynBIOSU31_00455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynBIOSU31_00459	COG2885	chlorophyll binding
SynBIOSU31_00460	COG2885	chlorophyll binding
SynBIOSU31_00468	COG0463	Glycosyl transferase, family 2
SynBIOSU31_00474	COG0469	pyruvate kinase activity
SynBIOSU31_00477	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynBIOSU31_00479	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynBIOSU31_00482	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynBIOSU31_00483	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynBIOSU31_00484	COG0101	tRNA pseudouridine synthase activity
SynBIOSU31_00485	COG0203	ribosomal protein L17
SynBIOSU31_00486	COG0202	RNA polymerase activity
SynBIOSU31_00487	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynBIOSU31_00488	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynBIOSU31_00490	COG0563	adenylate kinase activity
SynBIOSU31_00491	COG0201	protein transport
SynBIOSU31_00492	COG0200	Binds to the 23S rRNA
SynBIOSU31_00493	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynBIOSU31_00494	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynBIOSU31_00495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynBIOSU31_00496	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynBIOSU31_00497	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynBIOSU31_00498	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynBIOSU31_00499	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynBIOSU31_00500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynBIOSU31_00501	COG0255	Belongs to the universal ribosomal protein uL29 family
SynBIOSU31_00502	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynBIOSU31_00503	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynBIOSU31_00504	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynBIOSU31_00505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynBIOSU31_00506	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynBIOSU31_00507	COG0089	rRNA binding
SynBIOSU31_00508	COG0088	Forms part of the polypeptide exit tunnel
SynBIOSU31_00509	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynBIOSU31_00512	COG3854	ATPases associated with a variety of cellular activities
SynBIOSU31_00515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynBIOSU31_00521	COG3001	Fructosamine kinase
SynBIOSU31_00525	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynBIOSU31_00526	COG1606	tRNA processing
SynBIOSU31_00527	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynBIOSU31_00528	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynBIOSU31_00531	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynBIOSU31_00532	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynBIOSU31_00533	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynBIOSU31_00536	COG0772	Belongs to the SEDS family
SynBIOSU31_00537	COG0489	protein tyrosine kinase activity
SynBIOSU31_00538	COG0408	coproporphyrinogen oxidase activity
SynBIOSU31_00551	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynBIOSU31_00552	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynBIOSU31_00553	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynBIOSU31_00553	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynBIOSU31_00554	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynBIOSU31_00583	COG0237	dephospho-CoA kinase activity
SynBIOSU31_00588	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_00607	COG1070	Carbohydrate kinase
SynBIOSU31_00608	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynBIOSU31_00610	COG0539	negative regulation of cytoplasmic translation
SynBIOSU31_00611	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynBIOSU31_00618	COG0758	DNA mediated transformation
SynBIOSU31_00619	COG2890	protein-(glutamine-N5) methyltransferase activity
SynBIOSU31_00620	COG0009	L-threonylcarbamoyladenylate synthase
SynBIOSU31_00625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynBIOSU31_00626	COG2894	cell division
SynBIOSU31_00627	COG0850	regulation of cytokinetic process
SynBIOSU31_00628	COG1078	dGTPase activity
SynBIOSU31_00629	COG0793	Belongs to the peptidase S41A family
SynBIOSU31_00630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynBIOSU31_00631	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynBIOSU31_00640	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynBIOSU31_00642	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynBIOSU31_00645	COG0514	ATP-dependent DNA helicase (RecQ)
SynBIOSU31_00646	COG1388	LysM domain
SynBIOSU31_00646	COG0791	NLP P60 protein
SynBIOSU31_00647	COG1012	belongs to the aldehyde dehydrogenase family
SynBIOSU31_00649	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynBIOSU31_00652	COG2197	response regulator
SynBIOSU31_00657	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynBIOSU31_00660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynBIOSU31_00664	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynBIOSU31_00669	COG1160	GTP binding
SynBIOSU31_00670	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynBIOSU31_00672	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynBIOSU31_00673	COG1799	cell septum assembly
SynBIOSU31_00674	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynBIOSU31_00676	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_00678	COG1381	Involved in DNA repair and RecF pathway recombination
SynBIOSU31_00679	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynBIOSU31_00680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynBIOSU31_00681	COG0321	lipoyl(octanoyl) transferase activity
SynBIOSU31_00682	COG1022	Amp-dependent synthetase and ligase
SynBIOSU31_00684	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynBIOSU31_00685	COG0531	amino acid
SynBIOSU31_00686	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynBIOSU31_00687	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynBIOSU31_00688	COG0626	cystathionine gamma-synthase activity
SynBIOSU31_00702	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynBIOSU31_00704	COG1104	cysteine desulfurase activity
SynBIOSU31_00708	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynBIOSU31_00709	COG0579	oxidoreductase
SynBIOSU31_00712	COG3119	arylsulfatase activity
SynBIOSU31_00718	COG4969	Belongs to the N-Me-Phe pilin family
SynBIOSU31_00721	COG0481	GTPase activity
SynBIOSU31_00723	COG4968	Prepilin-type N-terminal cleavage methylation domain
SynBIOSU31_00724	COG2205	protein histidine kinase activity
SynBIOSU31_00724	COG2972	Histidine kinase
SynBIOSU31_00725	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_00731	COG5002	protein histidine kinase activity
SynBIOSU31_00732	COG4176	ABC-type proline glycine betaine transport system permease component
SynBIOSU31_00734	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBIOSU31_00735	COG0316	Belongs to the HesB IscA family
SynBIOSU31_00739	COG3695	enzyme binding
SynBIOSU31_00742	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynBIOSU31_00742	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynBIOSU31_00752	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynBIOSU31_00753	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBIOSU31_00755	COG0107	imidazoleglycerol-phosphate synthase activity
SynBIOSU31_00757	COG2226	methyltransferase
SynBIOSU31_00759	COG0752	glycyl-tRNA synthetase alpha subunit
SynBIOSU31_00760	COG0658	competence protein
SynBIOSU31_00760	COG2333	competence protein COMEC
SynBIOSU31_00763	COG0582	viral genome integration into host DNA
SynBIOSU31_00781	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBIOSU31_00782	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynBIOSU31_00783	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynBIOSU31_00784	COG0740	serine-type endopeptidase activity
SynBIOSU31_00785	COG0740	serine-type endopeptidase activity
SynBIOSU31_00786	COG4956	integral membrane protein (PIN domain superfamily)
SynBIOSU31_00787	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynBIOSU31_00788	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynBIOSU31_00789	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynBIOSU31_00792	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynBIOSU31_00793	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBIOSU31_00800	COG0402	S-adenosylhomocysteine deaminase activity
SynBIOSU31_00803	COG0285	dihydrofolate synthase activity
SynBIOSU31_00804	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynBIOSU31_00806	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynBIOSU31_00807	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynBIOSU31_00810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBIOSU31_00811	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynBIOSU31_00812	COG0134	indole-3-glycerol-phosphate synthase activity
SynBIOSU31_00817	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynBIOSU31_00818	COG0482	sulfurtransferase activity
SynBIOSU31_00819	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynBIOSU31_00819	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynBIOSU31_00821	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_00822	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynBIOSU31_00823	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynBIOSU31_00825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynBIOSU31_00826	COG0228	four-way junction DNA binding
SynBIOSU31_00827	COG1702	phosphate starvation-inducible protein PhoH
SynBIOSU31_00831	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynBIOSU31_00833	COG0336	Belongs to the RNA methyltransferase TrmD family
SynBIOSU31_00834	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynBIOSU31_00836	COG1691	(AIR) carboxylase
SynBIOSU31_00840	COG0352	thiamine-phosphate diphosphorylase activity
SynBIOSU31_00842	COG0196	riboflavin kinase activity
SynBIOSU31_00844	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynBIOSU31_00845	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynBIOSU31_00846	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynBIOSU31_00847	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_00872	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBIOSU31_00874	COG3119	arylsulfatase activity
SynBIOSU31_00880	COG3119	arylsulfatase activity
SynBIOSU31_00894	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynBIOSU31_00894	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynBIOSU31_00896	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_00897	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynBIOSU31_00900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynBIOSU31_00913	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynBIOSU31_00966	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBIOSU31_00991	COG1742	UPF0060 membrane protein
SynBIOSU31_01002	COG0477	Major facilitator Superfamily
SynBIOSU31_01003	COG0432	Pfam Uncharacterised protein family UPF0047
SynBIOSU31_01009	COG1492	cobalamin metabolic process
SynBIOSU31_01013	COG2274	protein secretion by the type I secretion system
SynBIOSU31_01017	COG0424	maF-like protein
SynBIOSU31_01023	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBIOSU31_01024	COG0440	acetolactate synthase activity
SynBIOSU31_01025	COG2267	carboxylic ester hydrolase activity
SynBIOSU31_01028	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_01030	COG2226	methyltransferase
SynBIOSU31_01031	COG1187	pseudouridine synthase activity
SynBIOSU31_01033	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynBIOSU31_01034	COG0492	ferredoxin-NADP+ reductase activity
SynBIOSU31_01041	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SynBIOSU31_01044	COG3411	Ferredoxin
SynBIOSU31_01045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynBIOSU31_01046	COG0733	neurotransmitter:sodium symporter activity
SynBIOSU31_01049	COG0215	cysteine-tRNA ligase activity
SynBIOSU31_01052	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBIOSU31_01052	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBIOSU31_01053	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynBIOSU31_01054	COG0012	GTP binding
SynBIOSU31_01056	COG0678	peroxiredoxin activity
SynBIOSU31_01058	COG4095	Psort location CytoplasmicMembrane, score
SynBIOSU31_01062	COG0601	transmembrane transport
SynBIOSU31_01065	COG0460	homoserine dehydrogenase
SynBIOSU31_01066	COG2166	iron-sulfur cluster assembly
SynBIOSU31_01086	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynBIOSU31_01087	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBIOSU31_01091	COG2010	Cytochrome c
SynBIOSU31_01093	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynBIOSU31_01094	COG3118	belongs to the thioredoxin family
SynBIOSU31_01095	COG0516	GMP reductase activity
SynBIOSU31_01097	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynBIOSU31_01098	COG0644	oxidoreductase
SynBIOSU31_01099	COG1543	Belongs to the glycosyl hydrolase 57 family
SynBIOSU31_01100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynBIOSU31_01101	COG0395	ABC-type sugar transport system, permease component
SynBIOSU31_01108	COG0011	TIGRFAM Protein of
SynBIOSU31_01111	COG0564	pseudouridine synthase activity
SynBIOSU31_01112	COG1480	7TM receptor with intracellular HD hydrolase
SynBIOSU31_01113	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynBIOSU31_01114	COG0142	geranyltranstransferase activity
SynBIOSU31_01119	COG1254	Belongs to the acylphosphatase family
SynBIOSU31_01120	COG1797	cobyrinic acid a,c-diamide synthase activity
SynBIOSU31_01121	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynBIOSU31_01121	COG3409	Peptidoglycan-binding domain 1 protein
SynBIOSU31_01122	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynBIOSU31_01123	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SynBIOSU31_01126	COG2205	protein histidine kinase activity
SynBIOSU31_01129	COG0308	aminopeptidase N
SynBIOSU31_01137	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynBIOSU31_01140	COG0702	epimerase
SynBIOSU31_01141	COG1640	4-alpha-glucanotransferase
SynBIOSU31_01143	COG1187	pseudouridine synthase activity
SynBIOSU31_01144	COG5002	protein histidine kinase activity
SynBIOSU31_01145	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_01146	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_01148	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBIOSU31_01151	COG1982	Orn Lys Arg decarboxylase major
SynBIOSU31_01152	COG0575	Belongs to the CDS family
SynBIOSU31_01154	COG0596	Alpha beta hydrolase
SynBIOSU31_01155	COG0371	Dehydrogenase
SynBIOSU31_01156	COG0542	response to heat
SynBIOSU31_01158	COG0456	acetyltransferase
SynBIOSU31_01159	COG0019	diaminopimelate decarboxylase activity
SynBIOSU31_01160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynBIOSU31_01161	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynBIOSU31_01162	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynBIOSU31_01163	COG1054	Belongs to the UPF0176 family
SynBIOSU31_01166	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynBIOSU31_01167	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynBIOSU31_01177	COG0589	response to stress
SynBIOSU31_01177	COG0475	glutathione-regulated potassium exporter activity
SynBIOSU31_01178	COG1132	(ABC) transporter
SynBIOSU31_01179	COG0724	RNA recognition motif
SynBIOSU31_01182	COG0513	Belongs to the DEAD box helicase family
SynBIOSU31_01184	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynBIOSU31_01185	COG1074	ATP-dependent DNA helicase activity
SynBIOSU31_01186	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynBIOSU31_01202	COG3239	Fatty acid desaturase
SynBIOSU31_01268	COG1525	nuclease
SynBIOSU31_01281	COG2197	response regulator
SynBIOSU31_01300	COG4106	trans-aconitate 2-methyltransferase activity
SynBIOSU31_01301	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynBIOSU31_01304	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynBIOSU31_01305	COG1122	ATPase activity
SynBIOSU31_01310	COG1836	PFAM Integral membrane protein DUF92
SynBIOSU31_01333	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynBIOSU31_01338	COG0793	Belongs to the peptidase S41A family
SynBIOSU31_01339	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynBIOSU31_01341	COG1573	uracil-dna glycosylase
SynBIOSU31_01343	COG0436	Aminotransferase
SynBIOSU31_01344	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynBIOSU31_01345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynBIOSU31_01345	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynBIOSU31_01346	COG3639	organic phosphonate transmembrane transporter activity
SynBIOSU31_01363	COG1126	abc transporter atp-binding protein
SynBIOSU31_01364	COG0765	amino acid transport
SynBIOSU31_01366	COG4597	amino acid ABC transporter
SynBIOSU31_01367	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynBIOSU31_01369	COG0659	secondary active sulfate transmembrane transporter activity
SynBIOSU31_01373	COG0668	transmembrane transport
SynBIOSU31_01377	COG0799	negative regulation of ribosome biogenesis
SynBIOSU31_01379	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynBIOSU31_01381	COG1115	amino acid carrier protein
SynBIOSU31_01383	COG1132	(ABC) transporter
SynBIOSU31_01385	COG0149	triose-phosphate isomerase activity
SynBIOSU31_01386	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynBIOSU31_01388	COG1429	ligase activity, forming nitrogen-metal bonds
SynBIOSU31_01389	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynBIOSU31_01391	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_01394	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynBIOSU31_01411	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SynBIOSU31_01415	COG3659	wide pore channel activity
SynBIOSU31_01417	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynBIOSU31_01418	COG1494	fructose-1,6-bisphosphatase
SynBIOSU31_01419	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynBIOSU31_01420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_01421	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynBIOSU31_01422	COG0363	glucosamine-6-phosphate deaminase activity
SynBIOSU31_01425	COG0129	dihydroxy-acid dehydratase activity
SynBIOSU31_01427	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynBIOSU31_01428	COG1357	PFAM Pentapeptide repeats (8 copies)
SynBIOSU31_01430	COG3895	Periplasmic Protein
SynBIOSU31_01433	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_01435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynBIOSU31_01436	COG0047	phosphoribosylformylglycinamidine synthase activity
SynBIOSU31_01438	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynBIOSU31_01441	COG0191	fructose-bisphosphate aldolase activity
SynBIOSU31_01442	COG3588	fructose-bisphosphate aldolase
SynBIOSU31_01444	COG0673	inositol 2-dehydrogenase activity
SynBIOSU31_01446	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynBIOSU31_01447	COG1528	Iron-storage protein
SynBIOSU31_01448	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynBIOSU31_01450	COG3954	Phosphoribulokinase
SynBIOSU31_01451	COG0473	3-isopropylmalate dehydrogenase activity
SynBIOSU31_01452	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBIOSU31_01457	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynBIOSU31_01460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynBIOSU31_01463	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynBIOSU31_01464	COG2197	response regulator
SynBIOSU31_01466	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynBIOSU31_01469	COG0517	IMP dehydrogenase activity
SynBIOSU31_01471	COG1376	ErfK ybiS ycfS ynhG family protein
SynBIOSU31_01476	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_01478	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynBIOSU31_01486	COG1119	ATPase activity
SynBIOSU31_01514	COG1201	RNA secondary structure unwinding
SynBIOSU31_01515	COG1793	dna ligase
SynBIOSU31_01520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SynBIOSU31_01527	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynBIOSU31_01529	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynBIOSU31_01545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynBIOSU31_01550	COG0740	serine-type endopeptidase activity
SynBIOSU31_01551	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_01552	COG0577	efflux transmembrane transporter activity
SynBIOSU31_01552	COG1136	(ABC) transporter
SynBIOSU31_01553	COG0469	pyruvate kinase activity
SynBIOSU31_01557	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynBIOSU31_01558	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynBIOSU31_01563	COG3842	ATPase activity
SynBIOSU31_01566	COG1653	transport
SynBIOSU31_01567	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynBIOSU31_01568	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBIOSU31_01569	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynBIOSU31_01570	COG0326	Molecular chaperone. Has ATPase activity
SynBIOSU31_01572	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynBIOSU31_01573	COG0483	inositol monophosphate 1-phosphatase activity
SynBIOSU31_01576	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynBIOSU31_01579	COG0443	Heat shock 70 kDa protein
SynBIOSU31_01580	COG0484	heat shock protein binding
SynBIOSU31_01582	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynBIOSU31_01583	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynBIOSU31_01584	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBIOSU31_01585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynBIOSU31_01585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynBIOSU31_01586	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynBIOSU31_01587	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynBIOSU31_01592	COG0166	Belongs to the GPI family
SynBIOSU31_01593	COG0495	leucyl-tRNA aminoacylation
SynBIOSU31_01599	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynBIOSU31_01605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynBIOSU31_01606	COG0322	excinuclease ABC activity
SynBIOSU31_01608	COG3046	protein related to deoxyribodipyrimidine photolyase
SynBIOSU31_01609	COG1981	membrane
SynBIOSU31_01610	COG0613	PHP domain protein
SynBIOSU31_01613	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynBIOSU31_01614	COG0646	methionine synthase
SynBIOSU31_01614	COG1410	methionine synthase
SynBIOSU31_01619	COG2385	sporulation resulting in formation of a cellular spore
SynBIOSU31_01626	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynBIOSU31_01627	COG0072	phenylalanine-tRNA ligase activity
SynBIOSU31_01628	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynBIOSU31_01629	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynBIOSU31_01630	COG0557	exoribonuclease II activity
SynBIOSU31_01632	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynBIOSU31_01639	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynBIOSU31_01640	COG0739	heme binding
SynBIOSU31_01643	COG0450	alkyl hydroperoxide reductase
SynBIOSU31_01644	COG1615	UPF0182 protein
SynBIOSU31_01645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_01646	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynBIOSU31_01649	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynBIOSU31_01650	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynBIOSU31_01650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynBIOSU31_01655	COG2119	membrane
SynBIOSU31_01657	COG0557	exoribonuclease II activity
SynBIOSU31_01658	COG0163	prenyltransferase activity
SynBIOSU31_01661	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynBIOSU31_01662	COG0312	modulator of DNA gyrase
SynBIOSU31_01664	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynBIOSU31_01665	COG0513	Belongs to the DEAD box helicase family
SynBIOSU31_01668	COG0861	Integral membrane protein TerC family
SynBIOSU31_01671	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynBIOSU31_01674	COG0271	Belongs to the BolA IbaG family
SynBIOSU31_01675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynBIOSU31_01676	COG0596	Alpha beta hydrolase
SynBIOSU31_01678	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_01681	COG0076	glutamate decarboxylase activity
SynBIOSU31_01682	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBIOSU31_01685	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynBIOSU31_01690	COG4565	transcriptional regulatory protein
SynBIOSU31_01706	COG0735	belongs to the Fur family
SynBIOSU31_01708	COG1799	cell septum assembly
SynBIOSU31_01727	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynBIOSU31_01736	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynBIOSU31_01741	COG1217	gtp-binding protein TYPA
SynBIOSU31_01743	COG0644	oxidoreductase
SynBIOSU31_01744	COG0751	glycine-tRNA ligase activity
SynBIOSU31_01745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynBIOSU31_01746	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynBIOSU31_01747	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynBIOSU31_01749	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynBIOSU31_01750	COG0052	Belongs to the universal ribosomal protein uS2 family
SynBIOSU31_01751	COG1216	Glycosyl transferase, family 2
SynBIOSU31_01757	COG0612	Peptidase, M16
SynBIOSU31_01761	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynBIOSU31_01762	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynBIOSU31_01765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynBIOSU31_01767	COG0174	glutamine synthetase
SynBIOSU31_01771	COG2226	methyltransferase
SynBIOSU31_01776	COG0515	serine threonine protein kinase
SynBIOSU31_01777	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynBIOSU31_01779	COG0628	permease
SynBIOSU31_01784	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynBIOSU31_01785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynBIOSU31_01786	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynBIOSU31_01786	COG0022	dehydrogenase e1 component
SynBIOSU31_01788	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynBIOSU31_01789	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynBIOSU31_01794	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynBIOSU31_01797	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynBIOSU31_01843	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_01845	COG0358	DNA primase activity
SynBIOSU31_01846	COG1566	PFAM secretion protein HlyD family protein
SynBIOSU31_01848	COG0577	efflux transmembrane transporter activity
SynBIOSU31_01848	COG1136	(ABC) transporter
SynBIOSU31_01856	COG0632	four-way junction helicase activity
SynBIOSU31_01857	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynBIOSU31_01859	COG0587	DNA-directed DNA polymerase activity
SynBIOSU31_01860	COG0154	amidase activity
SynBIOSU31_01862	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBIOSU31_01863	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynBIOSU31_01865	COG0505	Belongs to the CarA family
SynBIOSU31_01866	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynBIOSU31_01868	COG1132	(ABC) transporter
SynBIOSU31_01870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_01874	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_01878	COG2176	DNA-directed DNA polymerase activity
SynBIOSU31_01879	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBIOSU31_01881	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynBIOSU31_01883	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynBIOSU31_01884	COG0142	geranyltranstransferase activity
SynBIOSU31_01885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynBIOSU31_01888	COG2045	Belongs to the ComB family
SynBIOSU31_01889	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynBIOSU31_01890	COG1840	ABC-type Fe3 transport system, periplasmic component
SynBIOSU31_01891	COG3128	pkhd-type hydroxylase
SynBIOSU31_01893	COG3659	wide pore channel activity
SynBIOSU31_01898	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynBIOSU31_01902	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynBIOSU31_01903	COG1597	lipid kinase activity
SynBIOSU31_01903	COG1803	Methylglyoxal synthase
SynBIOSU31_01906	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynBIOSU31_01908	COG0297	glycogen (starch) synthase activity
SynBIOSU31_01909	COG1376	ErfK ybiS ycfS ynhG family protein
SynBIOSU31_01910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SynBIOSU31_01911	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynBIOSU31_01912	COG0681	Belongs to the peptidase S26 family
SynBIOSU31_01920	COG0277	FAD linked oxidase domain protein
SynBIOSU31_01935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynBIOSU31_01937	COG3119	arylsulfatase activity
SynBIOSU31_01938	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBIOSU31_01972	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynBIOSU31_01973	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBIOSU31_01974	COG1121	(ABC) transporter
SynBIOSU31_01977	COG0701	Predicted permease
SynBIOSU31_01983	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBIOSU31_01984	COG1121	(ABC) transporter
SynBIOSU31_02022	COG2032	superoxide dismutase activity
SynBIOSU31_02023	COG0717	Belongs to the dCTP deaminase family
SynBIOSU31_02100	COG2094	Belongs to the DNA glycosylase MPG family
SynBIOSU31_02105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_02107	COG0300	oxidoreductase activity
SynBIOSU31_02116	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBIOSU31_02133	COG2234	aminopeptidase activity
SynBIOSU31_02140	COG0405	Gamma-glutamyltransferase
SynBIOSU31_02156	COG2720	vancomycin resistance protein
SynBIOSU31_02158	COG0523	cobalamin synthesis protein
SynBIOSU31_02160	COG1121	(ABC) transporter
SynBIOSU31_02161	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBIOSU31_02162	COG2124	cytochrome p450
SynBIOSU31_02181	COG0484	heat shock protein binding
SynBIOSU31_02239	COG2135	peptidase activity
SynBIOSU31_02246	COG2084	Dehydrogenase
SynBIOSU31_02253	COG0515	serine threonine protein kinase
SynBIOSU31_02266	COG3781	membrane
SynBIOSU31_02282	COG1233	COG1233 Phytoene dehydrogenase and related
SynBIOSU31_02293	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynBIOSU31_02294	COG0351	phosphomethylpyrimidine kinase
SynBIOSU31_02302	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynBIOSU31_02312	COG0180	Tryptophanyl-tRNA synthetase
SynBIOSU31_02317	COG0837	glucose binding
SynBIOSU31_02318	COG0083	homoserine kinase activity
SynBIOSU31_02319	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_02320	COG0339	signal peptide processing
SynBIOSU31_02326	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynBIOSU31_02327	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynBIOSU31_02335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynBIOSU31_02336	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynBIOSU31_02338	COG3794	PFAM blue (type 1) copper domain protein
SynBIOSU31_02347	COG0542	response to heat
SynBIOSU31_02349	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynBIOSU31_02349	COG0140	phosphoribosyl-ATP diphosphatase activity
SynBIOSU31_02350	COG1376	ErfK ybiS ycfS ynhG family protein
SynBIOSU31_02353	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_02354	COG3339	Conserved Protein
SynBIOSU31_02359	COG2010	Cytochrome c
SynBIOSU31_02362	COG0159	tryptophan synthase activity
SynBIOSU31_02367	COG0418	dihydroorotase activity
SynBIOSU31_02368	COG0659	secondary active sulfate transmembrane transporter activity
SynBIOSU31_02369	COG0530	calcium, potassium:sodium antiporter activity
SynBIOSU31_02373	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynBIOSU31_02376	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynBIOSU31_02380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynBIOSU31_02381	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBIOSU31_02384	COG0456	acetyltransferase
SynBIOSU31_02385	COG0596	Alpha beta hydrolase
SynBIOSU31_02386	COG1132	(ABC) transporter
SynBIOSU31_02387	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynBIOSU31_02388	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynBIOSU31_02389	COG3842	ATPase activity
SynBIOSU31_02390	COG0251	oxidation-reduction process
SynBIOSU31_02395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_02396	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynBIOSU31_02397	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBIOSU31_02402	COG4451	ribulose bisphosphate carboxylase, small
SynBIOSU31_02403	COG1850	ribulose-bisphosphate carboxylase activity
SynBIOSU31_02404	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBIOSU31_02405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynBIOSU31_02406	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBIOSU31_02409	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBIOSU31_02410	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBIOSU31_02411	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynBIOSU31_02417	COG0730	response to heat
SynBIOSU31_02418	COG0095	Lipoate-protein ligase
SynBIOSU31_02419	COG1994	Peptidase M50
SynBIOSU31_02419	COG0517	IMP dehydrogenase activity
SynBIOSU31_02420	COG0135	phosphoribosylanthranilate isomerase activity
SynBIOSU31_02422	COG0302	gtp cyclohydrolase
SynBIOSU31_02423	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_02424	COG0825	malonyl-CoA metabolic process
SynBIOSU31_02425	COG5322	oxidoreductase activity
SynBIOSU31_02426	COG3396	Phenylacetate-CoA oxygenase
SynBIOSU31_02428	COG0539	negative regulation of cytoplasmic translation
SynBIOSU31_02431	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynBIOSU31_02434	COG0028	Belongs to the TPP enzyme family
SynBIOSU31_02435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_02438	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SynBIOSU31_02439	COG2226	methyltransferase
SynBIOSU31_02442	COG0528	UMP kinase activity
SynBIOSU31_02443	COG0233	cytoplasmic translational termination
SynBIOSU31_02444	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
SynBIOSU31_02445	COG0415	Belongs to the DNA photolyase family
SynBIOSU31_02447	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynBIOSU31_02448	COG0768	penicillin binding
SynBIOSU31_02452	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SynBIOSU31_02453	COG0681	Belongs to the peptidase S26 family
SynBIOSU31_02457	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynBIOSU31_02461	COG0442	prolyl-tRNA aminoacylation
SynBIOSU31_02463	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynBIOSU31_02464	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynBIOSU31_02465	COG2099	Precorrin-6x reductase
SynBIOSU31_02466	COG0629	single-stranded DNA binding
SynBIOSU31_02469	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynBIOSU31_02471	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynBIOSU31_02472	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_02474	COG0181	hydroxymethylbilane synthase activity
SynBIOSU31_02475	COG2095	MarC family integral membrane protein
SynBIOSU31_02479	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynBIOSU31_02480	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynBIOSU31_02485	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynBIOSU31_02486	COG0523	cobalamin synthesis protein
SynBIOSU31_02491	COG1230	cation diffusion facilitator family transporter
SynBIOSU31_02493	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynBIOSU31_02501	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynBIOSU31_02503	COG1666	GTP binding
SynBIOSU31_02507	COG0330	HflC and HflK could
SynBIOSU31_02510	COG0857	belongs to the CobB CobQ family
SynBIOSU31_02512	COG3000	fatty acid hydroxylase
SynBIOSU31_02512	COG0300	oxidoreductase activity
SynBIOSU31_02513	COG0024	Methionine aminopeptidase
SynBIOSU31_02515	COG0335	large ribosomal subunit rRNA binding
SynBIOSU31_02519	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynBIOSU31_02520	COG3263	regulation of cellular component size
SynBIOSU31_02523	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SynBIOSU31_02525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_02526	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynBIOSU31_02529	COG0194	GDP metabolic process
SynBIOSU31_02531	COG0805	protein transport
SynBIOSU31_02533	COG0723	plastoquinol--plastocyanin reductase activity
SynBIOSU31_02534	COG0739	heme binding
SynBIOSU31_02535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SynBIOSU31_02544	COG0248	Ppx GppA phosphatase
SynBIOSU31_02545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBIOSU31_02546	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynBIOSU31_02547	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynBIOSU31_02549	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynBIOSU31_02550	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_02552	COG0459	protein refolding
SynBIOSU31_02554	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynBIOSU31_02558	COG0109	protoheme IX farnesyltransferase activity
SynBIOSU31_02559	COG1612	heme a metabolic process
SynBIOSU31_02562	COG1845	cytochrome c oxidase, subunit III
SynBIOSU31_02569	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynBIOSU31_02572	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynBIOSU31_02574	COG1007	ATP synthesis coupled electron transport
SynBIOSU31_02575	COG1136	(ABC) transporter
SynBIOSU31_02575	COG0577	efflux transmembrane transporter activity
SynBIOSU31_02576	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_02577	COG0739	heme binding
SynBIOSU31_02578	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynBIOSU31_02578	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynBIOSU31_02579	COG0436	Aminotransferase
SynBIOSU31_02580	COG1842	Phage shock protein A
SynBIOSU31_02582	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SynBIOSU31_02584	COG0697	spore germination
SynBIOSU31_02585	COG0616	signal peptide processing
SynBIOSU31_02589	COG0594	ribonuclease P activity
SynBIOSU31_02591	COG0706	membrane insertase activity
SynBIOSU31_02593	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_02595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynBIOSU31_02596	COG0750	zinc metalloprotease
SynBIOSU31_02597	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynBIOSU31_02598	COG1185	polyribonucleotide nucleotidyltransferase activity
SynBIOSU31_02599	COG1218	3'(2'),5'-bisphosphate nucleotidase
SynBIOSU31_02600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynBIOSU31_02647	COG0039	L-malate dehydrogenase activity
SynBIOSU31_02687	COG1970	mechanosensitive ion channel activity
SynBIOSU31_02692	COG0625	glutathione transferase activity
SynBIOSU31_02734	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynBIOSU31_02735	COG0776	regulation of translation
SynBIOSU31_02740	COG2211	Major facilitator Superfamily
SynBIOSU31_02741	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynBIOSU31_02744	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynBIOSU31_02745	COG0284	orotidine-5'-phosphate decarboxylase activity
SynBIOSU31_02746	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynBIOSU31_02751	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynBIOSU31_02754	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_02754	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_02756	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBIOSU31_02757	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynBIOSU31_02758	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynBIOSU31_02760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynBIOSU31_02762	COG0151	Belongs to the GarS family
SynBIOSU31_02763	COG5002	protein histidine kinase activity
SynBIOSU31_02764	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynBIOSU31_02765	COG4251	negative regulation of phosphorylation
SynBIOSU31_02767	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynBIOSU31_02768	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynBIOSU31_02770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBIOSU31_02773	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynBIOSU31_02774	COG0217	transcriptional regulatory protein
SynBIOSU31_02776	COG0363	glucosamine-6-phosphate deaminase activity
SynBIOSU31_02777	COG2385	sporulation resulting in formation of a cellular spore
SynBIOSU31_02778	COG1234	tRNA 3'-trailer cleavage
SynBIOSU31_02779	COG2010	Cytochrome c
SynBIOSU31_02782	COG2264	protein methyltransferase activity
SynBIOSU31_02783	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynBIOSU31_02788	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynBIOSU31_02799	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynBIOSU31_02802	COG0004	ammonium transporteR
SynBIOSU31_02803	COG0459	protein refolding
SynBIOSU31_02804	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynBIOSU31_02805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynBIOSU31_02806	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynBIOSU31_02808	COG0739	heme binding
SynBIOSU31_02812	COG0006	proline dipeptidase activity
SynBIOSU31_02813	COG1253	flavin adenine dinucleotide binding
SynBIOSU31_02814	COG1160	GTP binding
SynBIOSU31_02815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynBIOSU31_02816	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynBIOSU31_02816	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBIOSU31_02818	COG3012	SEC-C Motif Domain Protein
SynBIOSU31_02819	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBIOSU31_02822	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBIOSU31_02823	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynBIOSU31_02824	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynBIOSU31_02825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynBIOSU31_02826	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynBIOSU31_02827	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynBIOSU31_02828	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynBIOSU31_02829	COG0356	it plays a direct role in the translocation of protons across the membrane
SynBIOSU31_02831	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBIOSU31_02832	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_02836	COG0772	Belongs to the SEDS family
SynBIOSU31_02838	COG1333	cytochrome c biogenesis protein
SynBIOSU31_02839	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynBIOSU31_02842	COG0347	Belongs to the P(II) protein family
SynBIOSU31_02845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynBIOSU31_02846	COG0114	fumarate hydratase activity
SynBIOSU31_02847	COG4581	dead DEAH box helicase
SynBIOSU31_02848	COG0156	8-amino-7-oxononanoate synthase activity
SynBIOSU31_02851	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynBIOSU31_02851	COG4106	trans-aconitate 2-methyltransferase activity
SynBIOSU31_02854	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynBIOSU31_02857	COG0357	Ribosomal RNA small subunit methyltransferase G
SynBIOSU31_02866	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SynBIOSU31_02867	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynBIOSU31_02868	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_02869	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynBIOSU31_02870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynBIOSU31_02871	COG0085	RNA polymerase activity
SynBIOSU31_02873	COG0084	hydrolase, TatD family'
SynBIOSU31_02874	COG0268	Binds directly to 16S ribosomal RNA
SynBIOSU31_02875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynBIOSU31_02876	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynBIOSU31_02877	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBIOSU31_02880	COG0641	radical SAM
SynBIOSU31_02881	COG0779	Required for maturation of 30S ribosomal subunits
SynBIOSU31_02882	COG0195	Participates in both transcription termination and antitermination
SynBIOSU31_02884	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynBIOSU31_02901	COG2988	succinylglutamate desuccinylase activity
SynBIOSU31_02902	COG0435	Glutathione S-transferase
SynBIOSU31_02904	COG0488	(ABC) transporter
SynBIOSU31_02907	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynBIOSU31_02908	COG3842	ATPase activity
SynBIOSU31_02909	COG1193	negative regulation of DNA recombination
SynBIOSU31_02911	COG0113	porphobilinogen synthase activity
SynBIOSU31_02912	COG0484	heat shock protein binding
SynBIOSU31_02914	COG0659	secondary active sulfate transmembrane transporter activity
SynBIOSU31_02918	COG0492	ferredoxin-NADP+ reductase activity
SynBIOSU31_02931	COG2197	response regulator
SynBIOSU31_03006	COG0116	Belongs to the methyltransferase superfamily
SynBIOSU31_03010	COG1196	nuclear chromosome segregation
SynBIOSU31_03013	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_03016	COG0439	Biotin carboxylase
SynBIOSU31_03019	COG0515	serine threonine protein kinase
SynBIOSU31_03024	COG4178	(ABC) transporter
SynBIOSU31_03025	COG0537	adenosine 5'-monophosphoramidase activity
SynBIOSU31_03028	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynBIOSU31_03031	COG0242	peptide deformylase activity
SynBIOSU31_03034	COG0235	Class ii aldolase
SynBIOSU31_03035	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynBIOSU31_03036	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynBIOSU31_03037	COG0719	Fe-S assembly protein
SynBIOSU31_03038	COG0396	ATPase activity
SynBIOSU31_03039	COG0719	Fe-S assembly protein
SynBIOSU31_03044	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_03050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynBIOSU31_03061	COG0033	Phosphoglucomutase
SynBIOSU31_03063	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynBIOSU31_03065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SynBIOSU31_03069	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBIOSU31_03071	COG0175	sulfate reduction
SynBIOSU31_03072	COG1252	NADH dehydrogenase
SynBIOSU31_03073	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynBIOSU31_03074	COG0471	metal ion transport
SynBIOSU31_03074	COG3273	potassium ion transport
SynBIOSU31_03075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynBIOSU31_03076	COG0569	domain protein
SynBIOSU31_03077	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynBIOSU31_03082	COG0488	(ABC) transporter
SynBIOSU31_03084	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBIOSU31_03088	COG1643	Atp-dependent helicase
SynBIOSU31_03091	COG1570	exodeoxyribonuclease VII activity
SynBIOSU31_03103	COG0483	inositol monophosphate 1-phosphatase activity
SynBIOSU31_03106	COG1968	undecaprenyl-diphosphatase activity
SynBIOSU31_03108	COG1555	photosystem II stabilization
SynBIOSU31_03109	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynBIOSU31_03110	COG4243	Vitamin k epoxide reductase
SynBIOSU31_03111	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBIOSU31_03114	COG1032	radical SAM domain protein
SynBIOSU31_03120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynBIOSU31_03128	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynBIOSU31_03129	COG1472	Belongs to the glycosyl hydrolase 3 family
SynBIOSU31_03130	COG0457	Tetratricopeptide repeat
SynBIOSU31_03130	COG0463	Glycosyl transferase, family 2
SynBIOSU31_03131	COG1587	Uroporphyrinogen-III synthase
SynBIOSU31_03134	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBIOSU31_03135	COG0316	Belongs to the HesB IscA family
SynBIOSU31_03138	COG1090	epimerase
SynBIOSU31_03139	COG3263	regulation of cellular component size
SynBIOSU31_03142	COG0484	heat shock protein binding
SynBIOSU31_03143	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynBIOSU31_03144	COG3659	wide pore channel activity
SynBIOSU31_03148	COG0463	Glycosyl transferase, family 2
SynBIOSU31_03155	COG1122	ATPase activity
SynBIOSU31_03157	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_03159	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynBIOSU31_03160	COG2217	Heavy metal translocating P-type atpase
SynBIOSU31_03161	COG3063	Type IV pilus biogenesis stability protein PilW
SynBIOSU31_03162	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynBIOSU31_03164	COG0416	fatty acid biosynthetic process
SynBIOSU31_03165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynBIOSU31_03166	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynBIOSU31_03167	COG0318	PFAM AMP-dependent synthetase and ligase
SynBIOSU31_03167	COG0204	Acyl-transferase
SynBIOSU31_03169	COG1214	PFAM Peptidase M22, glycoprotease
SynBIOSU31_03171	COG0617	tRNA 3'-terminal CCA addition
SynBIOSU31_03173	COG1562	ergosterol biosynthetic process
SynBIOSU31_03174	COG0493	'glutamate synthase
SynBIOSU31_03174	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBIOSU31_03177	COG0583	DNA-binding transcription factor activity
SynBIOSU31_03179	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynBIOSU31_03180	COG3659	wide pore channel activity
SynBIOSU31_03181	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_03183	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynBIOSU31_03185	COG2197	response regulator
SynBIOSU31_03188	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynBIOSU31_03189	COG0713	ATP synthesis coupled electron transport
SynBIOSU31_03190	COG0839	Belongs to the complex I subunit 6 family
SynBIOSU31_03191	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_03192	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynBIOSU31_03193	COG0372	Belongs to the citrate synthase family
SynBIOSU31_03197	COG1420	regulation of RNA biosynthetic process
SynBIOSU31_03198	COG0133	tryptophan synthase activity
SynBIOSU31_03200	COG0023	Translation Initiation Factor
SynBIOSU31_03201	COG0529	Catalyzes the synthesis of activated sulfate
SynBIOSU31_03202	COG0628	permease
SynBIOSU31_03204	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynBIOSU31_03205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SynBIOSU31_03206	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBIOSU31_03208	COG0564	pseudouridine synthase activity
SynBIOSU31_03209	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_03211	COG1104	cysteine desulfurase activity
SynBIOSU31_03214	COG0275	rRNA processing
SynBIOSU31_03215	COG0649	NAD binding
SynBIOSU31_03217	COG0824	Thioesterase
SynBIOSU31_03222	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_03226	COG1575	Belongs to the MenA family. Type 1 subfamily
SynBIOSU31_03229	COG0189	ligase activity
SynBIOSU31_03230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynBIOSU31_03232	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynBIOSU31_03234	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynBIOSU31_03235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynBIOSU31_03236	COG0512	Glutamine amidotransferase of anthranilate synthase
SynBIOSU31_03238	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynBIOSU31_03240	COG0252	asparaginase activity
SynBIOSU31_03241	COG0018	arginyl-trna synthetase
SynBIOSU31_03242	COG0157	Belongs to the NadC ModD family
SynBIOSU31_03243	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynBIOSU31_03245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynBIOSU31_03246	COG4172	Belongs to the ABC transporter superfamily
SynBIOSU31_03251	COG0564	pseudouridine synthase activity
SynBIOSU31_03253	COG0589	response to stress
SynBIOSU31_03254	COG0126	phosphoglycerate kinase activity
SynBIOSU31_03264	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynBIOSU31_03265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynBIOSU31_03267	COG1450	Type ii and iii secretion system protein
SynBIOSU31_03271	COG0167	dihydroorotate dehydrogenase activity
SynBIOSU31_03272	COG0328	RNA-DNA hybrid ribonuclease activity
SynBIOSU31_03275	COG0222	ribosome binding
SynBIOSU31_03276	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynBIOSU31_03277	COG0081	regulation of translation
SynBIOSU31_03278	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynBIOSU31_03279	COG0250	Participates in transcription elongation, termination and antitermination
SynBIOSU31_03280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynBIOSU31_03281	COG0542	response to heat
SynBIOSU31_03282	COG0346	lactoylglutathione lyase activity
SynBIOSU31_03283	COG0148	phosphopyruvate hydratase activity
SynBIOSU31_03285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBIOSU31_03288	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynBIOSU31_03289	COG0237	dephospho-CoA kinase activity
SynBIOSU31_03293	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynBIOSU31_03294	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynBIOSU31_03294	COG2022	thiamine diphosphate biosynthetic process
SynBIOSU31_03295	COG0105	UTP biosynthetic process
SynBIOSU31_03296	COG1166	arginine decarboxylase activity
SynBIOSU31_03297	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_03308	COG1803	Methylglyoxal synthase
SynBIOSU31_03309	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SynBIOSU31_03313	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynBIOSU31_03315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynBIOSU31_03320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SynBIOSU31_03322	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SynBIOSU31_03323	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBIOSU31_03323	COG0426	domain, Protein
SynBIOSU31_03327	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBIOSU31_03327	COG0426	domain, Protein
SynBIOSU31_03333	COG0509	glycine decarboxylation via glycine cleavage system
SynBIOSU31_03334	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynBIOSU31_03338	COG0359	binds to the 23S rRNA
SynBIOSU31_03339	COG1372	Participates in initiation and elongation during chromosome replication
SynBIOSU31_03339	COG0305	Participates in initiation and elongation during chromosome replication
SynBIOSU31_03339	COG0305	Participates in initiation and elongation during chromosome replication
SynBIOSU31_03339	COG1372	Participates in initiation and elongation during chromosome replication
SynBIOSU31_03345	COG0445	tRNA wobble uridine modification
SynBIOSU31_03353	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynBIOSU31_03356	COG0398	Pfam SNARE associated Golgi protein
SynBIOSU31_03358	COG0668	transmembrane transport
SynBIOSU31_03359	COG0668	transmembrane transport
SynBIOSU31_03365	COG1131	(ABC) transporter
SynBIOSU31_03366	COG0525	valine-tRNA ligase activity
SynBIOSU31_03368	COG3264	Mechanosensitive ion channel
SynBIOSU31_03368	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynBIOSU31_03372	COG4221	oxidoreductase activity
SynBIOSU31_03378	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_03391	COG5002	protein histidine kinase activity
SynBIOSU31_03397	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_03401	COG3956	TIGRFAM MazG family protein
SynBIOSU31_03409	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynBIOSU31_03410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynBIOSU31_03411	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_03412	COG0783	Belongs to the Dps family
SynBIOSU31_03413	COG0504	CTP synthase activity
SynBIOSU31_03414	COG0602	queuosine metabolic process
SynBIOSU31_03415	COG4942	peptidase
SynBIOSU31_03416	COG4574	serine-type endopeptidase inhibitor activity
SynBIOSU31_03417	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynBIOSU31_03420	COG3769	mannosylglycerate metabolic process
SynBIOSU31_03421	COG0366	Alpha amylase catalytic
SynBIOSU31_03423	COG0804	urea catabolic process
SynBIOSU31_03424	COG0519	Catalyzes the synthesis of GMP from XMP
SynBIOSU31_03424	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynBIOSU31_03427	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynBIOSU31_03428	COG0746	molybdenum cofactor guanylyltransferase activity
SynBIOSU31_03430	COG2223	nitrite transmembrane transporter activity
SynBIOSU31_03431	COG0243	molybdopterin cofactor binding
SynBIOSU31_03435	COG0315	cyclic pyranopterin monophosphate synthase activity
SynBIOSU31_03436	COG0303	'Molybdopterin
SynBIOSU31_03437	COG0314	molybdopterin synthase activity
SynBIOSU31_03438	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SynBIOSU31_03439	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynBIOSU31_03440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynBIOSU31_03442	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynBIOSU31_03444	COG2116	formate transmembrane transporter activity
SynBIOSU31_03446	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynBIOSU31_03449	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynBIOSU31_03452	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynBIOSU31_03453	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_03454	COG0170	dolichyl monophosphate biosynthetic process
SynBIOSU31_03455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynBIOSU31_03456	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynBIOSU31_03460	COG0788	formyltetrahydrofolate deformylase activity
SynBIOSU31_03463	COG2022	thiamine diphosphate biosynthetic process
SynBIOSU31_03463	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynBIOSU31_03465	COG0443	Heat shock 70 kDa protein
SynBIOSU31_03466	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynBIOSU31_03468	COG0360	Binds together with S18 to 16S ribosomal RNA
SynBIOSU31_03470	COG0137	argininosuccinate synthase activity
SynBIOSU31_03473	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynBIOSU31_03476	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynBIOSU31_03477	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_03479	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynBIOSU31_03480	COG0497	DNA recombination
SynBIOSU31_03481	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBIOSU31_03483	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine