locus-tag	class	description
SynBMKMC1_00001	COG0592	DNA-directed DNA polymerase activity
SynBMKMC1_00003	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynBMKMC1_00004	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SynBMKMC1_00005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynBMKMC1_00007	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynBMKMC1_00010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynBMKMC1_00011	COG0552	protein localization to endoplasmic reticulum
SynBMKMC1_00012	COG2208	phosphoserine phosphatase activity
SynBMKMC1_00013	COG0165	Argininosuccinate lyase
SynBMKMC1_00014	COG0724	RNA recognition motif
SynBMKMC1_00015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynBMKMC1_00017	COG2081	HI0933 family
SynBMKMC1_00018	COG1459	type II secretion system
SynBMKMC1_00020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynBMKMC1_00021	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynBMKMC1_00022	COG0484	heat shock protein binding
SynBMKMC1_00024	COG1162	GTPase activity
SynBMKMC1_00025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynBMKMC1_00026	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynBMKMC1_00027	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynBMKMC1_00028	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynBMKMC1_00029	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynBMKMC1_00030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBMKMC1_00031	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynBMKMC1_00032	COG0511	ligase activity, forming carbon-carbon bonds
SynBMKMC1_00033	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynBMKMC1_00048	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynBMKMC1_00049	COG0519	Catalyzes the synthesis of GMP from XMP
SynBMKMC1_00049	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynBMKMC1_00052	COG0768	penicillin binding
SynBMKMC1_00053	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00056	COG2022	thiamine diphosphate biosynthetic process
SynBMKMC1_00059	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynBMKMC1_00060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynBMKMC1_00061	COG2385	sporulation resulting in formation of a cellular spore
SynBMKMC1_00062	COG1215	transferase activity, transferring glycosyl groups
SynBMKMC1_00063	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynBMKMC1_00065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynBMKMC1_00066	COG0740	serine-type endopeptidase activity
SynBMKMC1_00067	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynBMKMC1_00069	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynBMKMC1_00070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynBMKMC1_00071	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynBMKMC1_00073	COG0037	tRNA processing
SynBMKMC1_00080	COG2801	Transposase and inactivated derivatives
SynBMKMC1_00087	COG0037	tRNA processing
SynBMKMC1_00090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBMKMC1_00091	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBMKMC1_00092	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBMKMC1_00093	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBMKMC1_00096	COG0556	nucleotide-excision repair
SynBMKMC1_00099	COG2082	Precorrin-8x methylmutase
SynBMKMC1_00100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBMKMC1_00102	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynBMKMC1_00106	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SynBMKMC1_00108	COG1091	dTDP-4-dehydrorhamnose reductase activity
SynBMKMC1_00109	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBMKMC1_00114	COG0653	protein targeting
SynBMKMC1_00115	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00115	COG1216	Glycosyl transferase, family 2
SynBMKMC1_00129	COG1045	serine acetyltransferase
SynBMKMC1_00130	COG1725	Transcriptional regulator
SynBMKMC1_00132	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynBMKMC1_00133	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynBMKMC1_00134	COG0187	DNA topoisomerase II activity
SynBMKMC1_00134	COG1372	Participates in initiation and elongation during chromosome replication
SynBMKMC1_00136	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynBMKMC1_00137	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynBMKMC1_00138	COG0386	Belongs to the glutathione peroxidase family
SynBMKMC1_00139	COG2239	Acts as a magnesium transporter
SynBMKMC1_00140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_00147	COG0477	Major facilitator Superfamily
SynBMKMC1_00155	COG1070	Carbohydrate kinase
SynBMKMC1_00157	COG0802	atpase or kinase
SynBMKMC1_00158	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynBMKMC1_00159	COG0586	Pfam SNARE associated Golgi protein
SynBMKMC1_00160	COG0629	single-stranded DNA binding
SynBMKMC1_00166	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_00167	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynBMKMC1_00171	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynBMKMC1_00172	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBMKMC1_00173	COG1357	PFAM Pentapeptide repeats (8 copies)
SynBMKMC1_00173	COG0515	serine threonine protein kinase
SynBMKMC1_00174	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynBMKMC1_00175	COG2255	four-way junction helicase activity
SynBMKMC1_00177	COG1473	amidohydrolase
SynBMKMC1_00180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynBMKMC1_00182	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynBMKMC1_00183	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynBMKMC1_00184	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynBMKMC1_00185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_00186	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynBMKMC1_00187	COG0662	Cupin 2, conserved barrel domain protein
SynBMKMC1_00187	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynBMKMC1_00188	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynBMKMC1_00190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBMKMC1_00193	COG0571	ribonuclease III activity
SynBMKMC1_00197	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SynBMKMC1_00198	COG0058	SHG alpha-glucan phosphorylase activity
SynBMKMC1_00199	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SynBMKMC1_00200	COG0475	glutathione-regulated potassium exporter activity
SynBMKMC1_00204	COG0277	FAD linked oxidase domain protein
SynBMKMC1_00206	COG0247	lactate metabolic process
SynBMKMC1_00209	COG0538	isocitrate dehydrogenase activity
SynBMKMC1_00210	COG0463	Glycosyl transferase, family 2
SynBMKMC1_00213	COG5398	heme oxygenase
SynBMKMC1_00216	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00218	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00219	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00223	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynBMKMC1_00225	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SynBMKMC1_00226	COG0517	IMP dehydrogenase activity
SynBMKMC1_00226	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SynBMKMC1_00226	COG0617	tRNA 3'-terminal CCA addition
SynBMKMC1_00228	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynBMKMC1_00232	COG0709	Synthesizes selenophosphate from selenide and ATP
SynBMKMC1_00233	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynBMKMC1_00236	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBMKMC1_00244	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00256	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00259	COG0489	protein tyrosine kinase activity
SynBMKMC1_00263	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBMKMC1_00265	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBMKMC1_00266	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBMKMC1_00270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBMKMC1_00271	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBMKMC1_00281	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBMKMC1_00282	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBMKMC1_00291	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBMKMC1_00292	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBMKMC1_00294	COG3039	Transposase
SynBMKMC1_00296	COG1132	(ABC) transporter
SynBMKMC1_00297	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynBMKMC1_00301	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynBMKMC1_00308	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynBMKMC1_00315	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBMKMC1_00316	COG0367	asparagine synthase
SynBMKMC1_00317	COG3039	Transposase
SynBMKMC1_00320	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00324	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBMKMC1_00329	COG0297	glycogen (starch) synthase activity
SynBMKMC1_00332	COG0494	nUDIX hydrolase
SynBMKMC1_00350	COG0124	histidyl-tRNA synthetase
SynBMKMC1_00351	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynBMKMC1_00358	COG4447	cellulose binding
SynBMKMC1_00359	COG1773	rubredoxin
SynBMKMC1_00361	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_00362	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_00363	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_00364	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynBMKMC1_00365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynBMKMC1_00367	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBMKMC1_00367	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBMKMC1_00369	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SynBMKMC1_00370	COG0494	nUDIX hydrolase
SynBMKMC1_00371	COG0415	Belongs to the DNA photolyase family
SynBMKMC1_00372	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynBMKMC1_00377	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynBMKMC1_00378	COG0131	Imidazoleglycerol-phosphate dehydratase
SynBMKMC1_00379	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynBMKMC1_00382	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynBMKMC1_00386	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynBMKMC1_00387	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynBMKMC1_00390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynBMKMC1_00393	COG1253	flavin adenine dinucleotide binding
SynBMKMC1_00394	COG0673	inositol 2-dehydrogenase activity
SynBMKMC1_00398	COG0343	queuine tRNA-ribosyltransferase activity
SynBMKMC1_00399	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynBMKMC1_00404	COG0138	bifunctional purine biosynthesis protein purh
SynBMKMC1_00407	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynBMKMC1_00408	COG0004	ammonium transporteR
SynBMKMC1_00409	COG1489	DNA binding
SynBMKMC1_00410	COG0728	peptidoglycan biosynthetic process
SynBMKMC1_00415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynBMKMC1_00416	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynBMKMC1_00417	COG1546	Belongs to the CinA family
SynBMKMC1_00417	COG1058	Belongs to the CinA family
SynBMKMC1_00418	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynBMKMC1_00419	COG0066	3-isopropylmalate dehydratase activity
SynBMKMC1_00426	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynBMKMC1_00427	COG0193	aminoacyl-tRNA hydrolase activity
SynBMKMC1_00430	COG4372	Transposase
SynBMKMC1_00431	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBMKMC1_00432	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynBMKMC1_00434	COG0717	Belongs to the dCTP deaminase family
SynBMKMC1_00436	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynBMKMC1_00438	COG0741	lytic transglycosylase activity
SynBMKMC1_00440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynBMKMC1_00443	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynBMKMC1_00448	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynBMKMC1_00452	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynBMKMC1_00455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynBMKMC1_00456	COG2094	Belongs to the DNA glycosylase MPG family
SynBMKMC1_00457	COG0540	Belongs to the ATCase OTCase family
SynBMKMC1_00462	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBMKMC1_00465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynBMKMC1_00468	COG2046	Belongs to the sulfate adenylyltransferase family
SynBMKMC1_00468	COG0529	Catalyzes the synthesis of activated sulfate
SynBMKMC1_00469	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBMKMC1_00470	COG0800	Aldolase
SynBMKMC1_00472	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynBMKMC1_00473	COG0737	Belongs to the 5'-nucleotidase family
SynBMKMC1_00475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynBMKMC1_00476	COG2226	methyltransferase
SynBMKMC1_00478	COG4175	Glycine betaine
SynBMKMC1_00479	COG4176	ABC-type proline glycine betaine transport system permease component
SynBMKMC1_00480	COG2113	Glycine betaine
SynBMKMC1_00481	COG0385	Bile acid
SynBMKMC1_00483	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBMKMC1_00485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynBMKMC1_00486	COG0436	Aminotransferase
SynBMKMC1_00488	COG1530	ribonuclease E activity
SynBMKMC1_00489	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynBMKMC1_00492	COG2226	methyltransferase
SynBMKMC1_00493	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynBMKMC1_00494	COG0051	transcription antitermination factor activity, RNA binding
SynBMKMC1_00495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynBMKMC1_00496	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynBMKMC1_00497	COG0049	tRNA binding
SynBMKMC1_00498	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynBMKMC1_00501	COG0067	glutamate synthase
SynBMKMC1_00501	COG0069	glutamate synthase activity
SynBMKMC1_00501	COG0070	glutamate synthase
SynBMKMC1_00507	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynBMKMC1_00511	COG2885	chlorophyll binding
SynBMKMC1_00512	COG2885	chlorophyll binding
SynBMKMC1_00519	COG0463	Glycosyl transferase, family 2
SynBMKMC1_00524	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynBMKMC1_00526	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynBMKMC1_00527	COG0254	rRNA binding
SynBMKMC1_00528	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynBMKMC1_00529	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynBMKMC1_00530	COG0101	tRNA pseudouridine synthase activity
SynBMKMC1_00531	COG0203	ribosomal protein L17
SynBMKMC1_00532	COG0202	RNA polymerase activity
SynBMKMC1_00533	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynBMKMC1_00534	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynBMKMC1_00535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynBMKMC1_00536	COG0563	adenylate kinase activity
SynBMKMC1_00537	COG0201	protein transport
SynBMKMC1_00538	COG0200	Binds to the 23S rRNA
SynBMKMC1_00539	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynBMKMC1_00540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynBMKMC1_00541	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynBMKMC1_00542	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynBMKMC1_00543	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynBMKMC1_00544	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynBMKMC1_00545	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynBMKMC1_00546	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynBMKMC1_00547	COG0255	Belongs to the universal ribosomal protein uL29 family
SynBMKMC1_00548	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynBMKMC1_00549	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynBMKMC1_00550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynBMKMC1_00551	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynBMKMC1_00552	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynBMKMC1_00553	COG0089	rRNA binding
SynBMKMC1_00554	COG0088	Forms part of the polypeptide exit tunnel
SynBMKMC1_00555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynBMKMC1_00558	COG3854	ATPases associated with a variety of cellular activities
SynBMKMC1_00561	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynBMKMC1_00565	COG0287	Prephenate dehydrogenase
SynBMKMC1_00567	COG3001	Fructosamine kinase
SynBMKMC1_00571	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynBMKMC1_00572	COG1606	tRNA processing
SynBMKMC1_00573	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynBMKMC1_00574	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynBMKMC1_00577	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynBMKMC1_00578	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynBMKMC1_00579	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynBMKMC1_00582	COG0772	Belongs to the SEDS family
SynBMKMC1_00583	COG0489	protein tyrosine kinase activity
SynBMKMC1_00584	COG0408	coproporphyrinogen oxidase activity
SynBMKMC1_00595	COG0667	Aldo Keto reductase
SynBMKMC1_00597	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynBMKMC1_00599	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynBMKMC1_00600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynBMKMC1_00600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynBMKMC1_00601	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynBMKMC1_00602	COG1413	lyase activity
SynBMKMC1_00620	COG0237	dephospho-CoA kinase activity
SynBMKMC1_00624	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBMKMC1_00633	COG1070	Carbohydrate kinase
SynBMKMC1_00634	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynBMKMC1_00635	COG0546	phosphoglycolate phosphatase activity
SynBMKMC1_00636	COG0539	negative regulation of cytoplasmic translation
SynBMKMC1_00637	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynBMKMC1_00642	COG0589	response to stress
SynBMKMC1_00645	COG2890	protein-(glutamine-N5) methyltransferase activity
SynBMKMC1_00646	COG0009	L-threonylcarbamoyladenylate synthase
SynBMKMC1_00650	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynBMKMC1_00651	COG2894	cell division
SynBMKMC1_00652	COG0850	regulation of cytokinetic process
SynBMKMC1_00653	COG1078	dGTPase activity
SynBMKMC1_00654	COG0793	Belongs to the peptidase S41A family
SynBMKMC1_00655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynBMKMC1_00656	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynBMKMC1_00657	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SynBMKMC1_00666	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynBMKMC1_00667	COG0235	Class ii aldolase
SynBMKMC1_00668	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynBMKMC1_00672	COG0514	ATP-dependent DNA helicase (RecQ)
SynBMKMC1_00673	COG1705	Flagellar rod assembly protein muramidase FlgJ
SynBMKMC1_00673	COG1388	LysM domain
SynBMKMC1_00674	COG1012	belongs to the aldehyde dehydrogenase family
SynBMKMC1_00676	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynBMKMC1_00677	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SynBMKMC1_00682	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynBMKMC1_00687	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynBMKMC1_00691	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynBMKMC1_00694	COG1376	ErfK ybiS ycfS ynhG family protein
SynBMKMC1_00695	COG1160	GTP binding
SynBMKMC1_00696	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynBMKMC1_00698	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynBMKMC1_00699	COG1799	cell septum assembly
SynBMKMC1_00700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynBMKMC1_00701	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_00703	COG1381	Involved in DNA repair and RecF pathway recombination
SynBMKMC1_00704	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynBMKMC1_00705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynBMKMC1_00706	COG0321	lipoyl(octanoyl) transferase activity
SynBMKMC1_00707	COG1022	Amp-dependent synthetase and ligase
SynBMKMC1_00710	COG0531	amino acid
SynBMKMC1_00711	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynBMKMC1_00713	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynBMKMC1_00717	COG3239	Fatty acid desaturase
SynBMKMC1_00719	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SynBMKMC1_00722	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SynBMKMC1_00724	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynBMKMC1_00726	COG1104	cysteine desulfurase activity
SynBMKMC1_00732	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynBMKMC1_00733	COG0579	oxidoreductase
SynBMKMC1_00736	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynBMKMC1_00740	COG2095	MarC family integral membrane protein
SynBMKMC1_00741	COG0181	hydroxymethylbilane synthase activity
SynBMKMC1_00743	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_00744	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynBMKMC1_00746	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynBMKMC1_00749	COG0629	single-stranded DNA binding
SynBMKMC1_00751	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynBMKMC1_00752	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynBMKMC1_00754	COG0442	prolyl-tRNA aminoacylation
SynBMKMC1_00756	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynBMKMC1_00760	COG0681	Belongs to the peptidase S26 family
SynBMKMC1_00761	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SynBMKMC1_00766	COG0768	penicillin binding
SynBMKMC1_00767	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynBMKMC1_00769	COG0415	Belongs to the DNA photolyase family
SynBMKMC1_00771	COG0233	cytoplasmic translational termination
SynBMKMC1_00772	COG0528	UMP kinase activity
SynBMKMC1_00776	COG2226	methyltransferase
SynBMKMC1_00778	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBMKMC1_00779	COG0028	Belongs to the TPP enzyme family
SynBMKMC1_00783	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynBMKMC1_00786	COG0539	negative regulation of cytoplasmic translation
SynBMKMC1_00788	COG3396	Phenylacetate-CoA oxygenase
SynBMKMC1_00789	COG5322	oxidoreductase activity
SynBMKMC1_00790	COG0825	malonyl-CoA metabolic process
SynBMKMC1_00791	COG4221	oxidoreductase activity
SynBMKMC1_00792	COG0302	gtp cyclohydrolase
SynBMKMC1_00794	COG0135	phosphoribosylanthranilate isomerase activity
SynBMKMC1_00795	COG0517	IMP dehydrogenase activity
SynBMKMC1_00795	COG1994	Peptidase M50
SynBMKMC1_00796	COG0095	Lipoate-protein ligase
SynBMKMC1_00797	COG0730	response to heat
SynBMKMC1_00804	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynBMKMC1_00806	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBMKMC1_00807	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBMKMC1_00810	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBMKMC1_00811	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynBMKMC1_00813	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBMKMC1_00814	COG1850	ribulose-bisphosphate carboxylase activity
SynBMKMC1_00815	COG4451	ribulose bisphosphate carboxylase, small
SynBMKMC1_00820	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBMKMC1_00821	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynBMKMC1_00822	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_00828	COG0251	oxidation-reduction process
SynBMKMC1_00829	COG3842	ATPase activity
SynBMKMC1_00830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynBMKMC1_00831	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynBMKMC1_00832	COG1132	(ABC) transporter
SynBMKMC1_00834	COG0456	acetyltransferase
SynBMKMC1_00837	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBMKMC1_00838	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynBMKMC1_00843	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynBMKMC1_00844	COG0811	peptide transport
SynBMKMC1_00850	COG1845	cytochrome c oxidase, subunit III
SynBMKMC1_00851	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynBMKMC1_00852	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SynBMKMC1_00852	COG2010	Cytochrome c
SynBMKMC1_00856	COG0659	secondary active sulfate transmembrane transporter activity
SynBMKMC1_00857	COG0418	dihydroorotase activity
SynBMKMC1_00865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynBMKMC1_00865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynBMKMC1_00870	COG0159	tryptophan synthase activity
SynBMKMC1_00873	COG2010	Cytochrome c
SynBMKMC1_00879	COG3339	Conserved Protein
SynBMKMC1_00880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_00883	COG1376	ErfK ybiS ycfS ynhG family protein
SynBMKMC1_00884	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynBMKMC1_00884	COG0140	phosphoribosyl-ATP diphosphatase activity
SynBMKMC1_00886	COG0542	response to heat
SynBMKMC1_00890	COG3794	PFAM blue (type 1) copper domain protein
SynBMKMC1_00892	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynBMKMC1_00893	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynBMKMC1_00902	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynBMKMC1_00909	COG0339	signal peptide processing
SynBMKMC1_00910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_00911	COG0083	homoserine kinase activity
SynBMKMC1_00912	COG0837	glucose binding
SynBMKMC1_00914	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynBMKMC1_00918	COG0180	Tryptophanyl-tRNA synthetase
SynBMKMC1_00928	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SynBMKMC1_00929	COG0154	amidase activity
SynBMKMC1_00934	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBMKMC1_00935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynBMKMC1_00942	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynBMKMC1_00944	COG2226	methyltransferase
SynBMKMC1_00951	COG3781	membrane
SynBMKMC1_00955	COG1064	alcohol dehydrogenase
SynBMKMC1_00963	COG2084	Dehydrogenase
SynBMKMC1_01002	COG0484	heat shock protein binding
SynBMKMC1_01012	COG0405	Gamma-glutamyltransferase
SynBMKMC1_01015	COG3961	Belongs to the TPP enzyme family
SynBMKMC1_01019	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SynBMKMC1_01020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SynBMKMC1_01023	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBMKMC1_01027	COG0668	transmembrane transport
SynBMKMC1_01041	COG4221	oxidoreductase activity
SynBMKMC1_01051	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SynBMKMC1_01052	COG0671	phosphoesterase, PA-phosphatase related
SynBMKMC1_01053	COG3657	addiction module killer protein
SynBMKMC1_01054	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynBMKMC1_01056	COG2337	Toxic component of a toxin-antitoxin (TA) module
SynBMKMC1_01060	COG3153	acetyltransferase
SynBMKMC1_01082	COG0671	phosphoesterase, PA-phosphatase related
SynBMKMC1_01088	COG2361	Protein of unknown function DUF86
SynBMKMC1_01113	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynBMKMC1_01120	COG1598	PFAM Uncharacterised protein family UPF0150
SynBMKMC1_01125	COG0537	adenosine 5'-monophosphoramidase activity
SynBMKMC1_01131	COG4067	protein conserved in archaea
SynBMKMC1_01131	COG0189	ligase activity
SynBMKMC1_01147	COG2124	cytochrome p450
SynBMKMC1_01151	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SynBMKMC1_01154	COG0459	protein refolding
SynBMKMC1_01175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBMKMC1_01189	COG0300	oxidoreductase activity
SynBMKMC1_01212	COG0651	ATP synthesis coupled electron transport
SynBMKMC1_01213	COG1006	Multisubunit Na H antiporter MnhC subunit
SynBMKMC1_01221	COG1121	(ABC) transporter
SynBMKMC1_01222	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBMKMC1_01225	COG2010	Cytochrome c
SynBMKMC1_01226	COG0701	Predicted permease
SynBMKMC1_01229	COG1121	(ABC) transporter
SynBMKMC1_01230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBMKMC1_01233	COG3659	wide pore channel activity
SynBMKMC1_01265	COG0523	cobalamin synthesis protein
SynBMKMC1_01282	COG2132	Multicopper oxidase
SynBMKMC1_01285	COG5002	protein histidine kinase activity
SynBMKMC1_01300	COG0681	Belongs to the peptidase S26 family
SynBMKMC1_01301	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynBMKMC1_01303	COG1376	ErfK ybiS ycfS ynhG family protein
SynBMKMC1_01304	COG0297	glycogen (starch) synthase activity
SynBMKMC1_01306	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynBMKMC1_01308	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynBMKMC1_01310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynBMKMC1_01311	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynBMKMC1_01312	COG2045	Belongs to the ComB family
SynBMKMC1_01315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynBMKMC1_01316	COG0142	geranyltranstransferase activity
SynBMKMC1_01317	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynBMKMC1_01319	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynBMKMC1_01321	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBMKMC1_01322	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SynBMKMC1_01325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBMKMC1_01328	COG2146	nitrite reductase [NAD(P)H] activity
SynBMKMC1_01331	COG0189	ligase activity
SynBMKMC1_01336	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBMKMC1_01338	COG1132	(ABC) transporter
SynBMKMC1_01340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynBMKMC1_01341	COG0505	Belongs to the CarA family
SynBMKMC1_01343	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynBMKMC1_01344	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBMKMC1_01346	COG0154	amidase activity
SynBMKMC1_01347	COG0587	DNA-directed DNA polymerase activity
SynBMKMC1_01349	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynBMKMC1_01350	COG0632	four-way junction helicase activity
SynBMKMC1_01353	COG0358	DNA primase activity
SynBMKMC1_01354	COG0798	PFAM Bile acid sodium symporter
SynBMKMC1_01368	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynBMKMC1_01371	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynBMKMC1_01372	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynBMKMC1_01372	COG2308	Evidence 4 Homologs of previously reported genes of
SynBMKMC1_01377	COG0861	Integral membrane protein TerC family
SynBMKMC1_01381	COG0513	Belongs to the DEAD box helicase family
SynBMKMC1_01382	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynBMKMC1_01384	COG0312	modulator of DNA gyrase
SynBMKMC1_01385	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynBMKMC1_01388	COG0163	prenyltransferase activity
SynBMKMC1_01389	COG0557	exoribonuclease II activity
SynBMKMC1_01391	COG2119	membrane
SynBMKMC1_01395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynBMKMC1_01395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynBMKMC1_01399	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynBMKMC1_01400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBMKMC1_01401	COG1615	UPF0182 protein
SynBMKMC1_01402	COG0450	alkyl hydroperoxide reductase
SynBMKMC1_01405	COG0739	heme binding
SynBMKMC1_01407	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynBMKMC1_01413	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynBMKMC1_01416	COG0129	dihydroxy-acid dehydratase activity
SynBMKMC1_01418	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynBMKMC1_01421	COG2211	Major facilitator Superfamily
SynBMKMC1_01426	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynBMKMC1_01427	COG0047	phosphoribosylformylglycinamidine synthase activity
SynBMKMC1_01428	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynBMKMC1_01430	COG0191	fructose-bisphosphate aldolase activity
SynBMKMC1_01432	COG0673	inositol 2-dehydrogenase activity
SynBMKMC1_01434	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynBMKMC1_01435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynBMKMC1_01437	COG3954	Phosphoribulokinase
SynBMKMC1_01438	COG0473	3-isopropylmalate dehydrogenase activity
SynBMKMC1_01439	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBMKMC1_01440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynBMKMC1_01443	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynBMKMC1_01446	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynBMKMC1_01447	COG2197	response regulator
SynBMKMC1_01449	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynBMKMC1_01450	COG1090	epimerase
SynBMKMC1_01454	COG1376	ErfK ybiS ycfS ynhG family protein
SynBMKMC1_01459	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBMKMC1_01464	COG3659	wide pore channel activity
SynBMKMC1_01465	COG1119	ATPase activity
SynBMKMC1_01467	COG1051	belongs to the nudix hydrolase family
SynBMKMC1_01475	COG1201	RNA secondary structure unwinding
SynBMKMC1_01476	COG1793	dna ligase
SynBMKMC1_01478	COG1793	dna ligase
SynBMKMC1_01478	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SynBMKMC1_01485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynBMKMC1_01486	COG1175	transmembrane transport
SynBMKMC1_01487	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynBMKMC1_01491	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynBMKMC1_01496	COG0740	serine-type endopeptidase activity
SynBMKMC1_01498	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBMKMC1_01499	COG1136	(ABC) transporter
SynBMKMC1_01499	COG0577	efflux transmembrane transporter activity
SynBMKMC1_01500	COG0469	pyruvate kinase activity
SynBMKMC1_01504	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynBMKMC1_01505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynBMKMC1_01510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynBMKMC1_01511	COG0598	Magnesium transport protein CorA
SynBMKMC1_01513	COG3842	ATPase activity
SynBMKMC1_01516	COG1653	transport
SynBMKMC1_01517	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynBMKMC1_01518	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBMKMC1_01519	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynBMKMC1_01520	COG0326	Molecular chaperone. Has ATPase activity
SynBMKMC1_01522	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynBMKMC1_01523	COG0483	inositol monophosphate 1-phosphatase activity
SynBMKMC1_01524	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBMKMC1_01526	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynBMKMC1_01527	COG0581	inorganic phosphate transmembrane transporter activity
SynBMKMC1_01528	COG0573	inorganic phosphate transmembrane transporter activity
SynBMKMC1_01529	COG0443	Heat shock 70 kDa protein
SynBMKMC1_01530	COG0484	heat shock protein binding
SynBMKMC1_01532	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynBMKMC1_01533	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynBMKMC1_01534	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBMKMC1_01535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynBMKMC1_01535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynBMKMC1_01536	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynBMKMC1_01537	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynBMKMC1_01542	COG0166	Belongs to the GPI family
SynBMKMC1_01543	COG0495	leucyl-tRNA aminoacylation
SynBMKMC1_01545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynBMKMC1_01546	COG1104	cysteine desulfurase activity
SynBMKMC1_01551	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynBMKMC1_01552	COG0322	excinuclease ABC activity
SynBMKMC1_01554	COG3046	protein related to deoxyribodipyrimidine photolyase
SynBMKMC1_01555	COG1981	membrane
SynBMKMC1_01559	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynBMKMC1_01560	COG0646	methionine synthase
SynBMKMC1_01560	COG1410	methionine synthase
SynBMKMC1_01565	COG2385	sporulation resulting in formation of a cellular spore
SynBMKMC1_01573	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynBMKMC1_01574	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynBMKMC1_01574	COG0072	phenylalanine-tRNA ligase activity
SynBMKMC1_01575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynBMKMC1_01576	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynBMKMC1_01577	COG0557	exoribonuclease II activity
SynBMKMC1_01580	COG0363	glucosamine-6-phosphate deaminase activity
SynBMKMC1_01581	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynBMKMC1_01582	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBMKMC1_01583	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynBMKMC1_01584	COG1494	fructose-1,6-bisphosphatase
SynBMKMC1_01585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynBMKMC1_01588	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynBMKMC1_01593	COG1217	gtp-binding protein TYPA
SynBMKMC1_01594	COG0826	peptidase U32
SynBMKMC1_01596	COG0644	oxidoreductase
SynBMKMC1_01597	COG0751	glycine-tRNA ligase activity
SynBMKMC1_01598	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynBMKMC1_01599	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynBMKMC1_01600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynBMKMC1_01602	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynBMKMC1_01603	COG0052	Belongs to the universal ribosomal protein uS2 family
SynBMKMC1_01604	COG1216	Glycosyl transferase, family 2
SynBMKMC1_01606	COG0577	efflux transmembrane transporter activity
SynBMKMC1_01606	COG1136	(ABC) transporter
SynBMKMC1_01610	COG0612	Peptidase, M16
SynBMKMC1_01614	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynBMKMC1_01615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynBMKMC1_01619	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynBMKMC1_01621	COG0174	glutamine synthetase
SynBMKMC1_01624	COG2226	methyltransferase
SynBMKMC1_01629	COG0515	serine threonine protein kinase
SynBMKMC1_01630	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynBMKMC1_01632	COG0628	permease
SynBMKMC1_01634	COG0426	domain, Protein
SynBMKMC1_01634	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBMKMC1_01637	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynBMKMC1_01638	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynBMKMC1_01639	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynBMKMC1_01639	COG0022	dehydrogenase e1 component
SynBMKMC1_01642	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynBMKMC1_01643	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynBMKMC1_01645	COG0572	uridine kinase
SynBMKMC1_01650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynBMKMC1_01653	COG0271	Belongs to the BolA IbaG family
SynBMKMC1_01654	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynBMKMC1_01656	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_01658	COG1233	COG1233 Phytoene dehydrogenase and related
SynBMKMC1_01660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynBMKMC1_01662	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SynBMKMC1_01671	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SynBMKMC1_01673	COG0735	belongs to the Fur family
SynBMKMC1_01675	COG1799	cell septum assembly
SynBMKMC1_01683	COG0420	3'-5' exonuclease activity
SynBMKMC1_01687	COG0477	Major facilitator Superfamily
SynBMKMC1_01689	COG2873	o-acetylhomoserine
SynBMKMC1_01690	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynBMKMC1_01697	COG0765	amino acid transport
SynBMKMC1_01699	COG4597	amino acid ABC transporter
SynBMKMC1_01700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynBMKMC1_01702	COG0659	secondary active sulfate transmembrane transporter activity
SynBMKMC1_01713	COG0799	negative regulation of ribosome biogenesis
SynBMKMC1_01715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynBMKMC1_01717	COG1115	amino acid carrier protein
SynBMKMC1_01719	COG1132	(ABC) transporter
SynBMKMC1_01720	COG2501	S4 domain
SynBMKMC1_01722	COG0149	triose-phosphate isomerase activity
SynBMKMC1_01723	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynBMKMC1_01725	COG1429	ligase activity, forming nitrogen-metal bonds
SynBMKMC1_01726	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynBMKMC1_01728	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBMKMC1_01729	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynBMKMC1_01731	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynBMKMC1_01750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynBMKMC1_01751	COG0640	Transcriptional regulator
SynBMKMC1_01759	COG3639	organic phosphonate transmembrane transporter activity
SynBMKMC1_01760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynBMKMC1_01760	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynBMKMC1_01761	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynBMKMC1_01762	COG0436	Aminotransferase
SynBMKMC1_01764	COG1573	uracil-dna glycosylase
SynBMKMC1_01765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynBMKMC1_01766	COG0793	Belongs to the peptidase S41A family
SynBMKMC1_01770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynBMKMC1_01773	COG1191	sigma factor activity
SynBMKMC1_01774	COG1836	PFAM Integral membrane protein DUF92
SynBMKMC1_01779	COG1122	ATPase activity
SynBMKMC1_01780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynBMKMC1_01784	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynBMKMC1_01785	COG4106	trans-aconitate 2-methyltransferase activity
SynBMKMC1_01786	COG0668	transmembrane transport
SynBMKMC1_01795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynBMKMC1_01796	COG1074	ATP-dependent DNA helicase activity
SynBMKMC1_01797	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynBMKMC1_01799	COG0513	Belongs to the DEAD box helicase family
SynBMKMC1_01803	COG0724	RNA recognition motif
SynBMKMC1_01805	COG1132	(ABC) transporter
SynBMKMC1_01806	COG0589	response to stress
SynBMKMC1_01806	COG0475	glutathione-regulated potassium exporter activity
SynBMKMC1_01814	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynBMKMC1_01815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynBMKMC1_01818	COG1054	Belongs to the UPF0176 family
SynBMKMC1_01819	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynBMKMC1_01820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynBMKMC1_01821	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynBMKMC1_01822	COG0019	diaminopimelate decarboxylase activity
SynBMKMC1_01823	COG0456	acetyltransferase
SynBMKMC1_01825	COG0542	response to heat
SynBMKMC1_01826	COG0371	Dehydrogenase
SynBMKMC1_01827	COG2226	methyltransferase
SynBMKMC1_01827	COG0596	Alpha beta hydrolase
SynBMKMC1_01827	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SynBMKMC1_01829	COG0575	Belongs to the CDS family
SynBMKMC1_01830	COG1982	Orn Lys Arg decarboxylase major
SynBMKMC1_01832	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBMKMC1_01834	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_01835	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_01836	COG5002	protein histidine kinase activity
SynBMKMC1_01837	COG1187	pseudouridine synthase activity
SynBMKMC1_01839	COG1640	4-alpha-glucanotransferase
SynBMKMC1_01840	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
SynBMKMC1_01843	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynBMKMC1_01845	COG0308	aminopeptidase N
SynBMKMC1_01848	COG2205	protein histidine kinase activity
SynBMKMC1_01851	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SynBMKMC1_01853	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynBMKMC1_01854	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynBMKMC1_01854	COG3409	Peptidoglycan-binding domain 1 protein
SynBMKMC1_01855	COG1797	cobyrinic acid a,c-diamide synthase activity
SynBMKMC1_01856	COG1254	Belongs to the acylphosphatase family
SynBMKMC1_01857	COG0406	alpha-ribazole phosphatase activity
SynBMKMC1_01861	COG0142	geranyltranstransferase activity
SynBMKMC1_01862	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynBMKMC1_01863	COG1480	7TM receptor with intracellular HD hydrolase
SynBMKMC1_01864	COG0564	pseudouridine synthase activity
SynBMKMC1_01868	COG0011	TIGRFAM Protein of
SynBMKMC1_01872	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBMKMC1_01877	COG0395	ABC-type sugar transport system, permease component
SynBMKMC1_01878	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynBMKMC1_01879	COG1543	Belongs to the glycosyl hydrolase 57 family
SynBMKMC1_01880	COG0644	oxidoreductase
SynBMKMC1_01881	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynBMKMC1_01883	COG0516	GMP reductase activity
SynBMKMC1_01884	COG3118	belongs to the thioredoxin family
SynBMKMC1_01885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynBMKMC1_01887	COG2010	Cytochrome c
SynBMKMC1_01891	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBMKMC1_01892	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynBMKMC1_01893	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynBMKMC1_01896	COG2166	iron-sulfur cluster assembly
SynBMKMC1_01897	COG0460	homoserine dehydrogenase
SynBMKMC1_01900	COG0601	transmembrane transport
SynBMKMC1_01904	COG4095	Psort location CytoplasmicMembrane, score
SynBMKMC1_01906	COG0012	GTP binding
SynBMKMC1_01907	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynBMKMC1_01908	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBMKMC1_01908	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBMKMC1_01909	COG0215	cysteine-tRNA ligase activity
SynBMKMC1_01912	COG0733	neurotransmitter:sodium symporter activity
SynBMKMC1_01913	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynBMKMC1_01924	COG0492	ferredoxin-NADP+ reductase activity
SynBMKMC1_01925	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynBMKMC1_01928	COG1187	pseudouridine synthase activity
SynBMKMC1_01929	COG2226	methyltransferase
SynBMKMC1_01931	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBMKMC1_01934	COG2267	carboxylic ester hydrolase activity
SynBMKMC1_01935	COG0440	acetolactate synthase activity
SynBMKMC1_01936	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBMKMC1_01951	COG0424	maF-like protein
SynBMKMC1_01953	COG1492	cobalamin metabolic process
SynBMKMC1_01958	COG0432	Pfam Uncharacterised protein family UPF0047
SynBMKMC1_01959	COG0477	Major facilitator Superfamily
SynBMKMC1_01972	COG1970	mechanosensitive ion channel activity
SynBMKMC1_01978	COG2963	transposase activity
SynBMKMC1_01992	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynBMKMC1_01997	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynBMKMC1_01998	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBMKMC1_02002	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynBMKMC1_02002	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynBMKMC1_02017	COG3119	arylsulfatase activity
SynBMKMC1_02019	COG3119	arylsulfatase activity
SynBMKMC1_02025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBMKMC1_02038	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynBMKMC1_02040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBMKMC1_02041	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynBMKMC1_02042	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynBMKMC1_02044	COG0196	riboflavin kinase activity
SynBMKMC1_02046	COG0352	thiamine-phosphate diphosphorylase activity
SynBMKMC1_02051	COG1691	(AIR) carboxylase
SynBMKMC1_02053	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynBMKMC1_02054	COG0336	Belongs to the RNA methyltransferase TrmD family
SynBMKMC1_02056	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynBMKMC1_02060	COG0670	Belongs to the BI1 family
SynBMKMC1_02061	COG1702	phosphate starvation-inducible protein PhoH
SynBMKMC1_02062	COG0228	four-way junction DNA binding
SynBMKMC1_02063	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynBMKMC1_02066	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynBMKMC1_02067	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynBMKMC1_02068	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_02069	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynBMKMC1_02069	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynBMKMC1_02070	COG0482	sulfurtransferase activity
SynBMKMC1_02071	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynBMKMC1_02074	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SynBMKMC1_02075	COG0134	indole-3-glycerol-phosphate synthase activity
SynBMKMC1_02076	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynBMKMC1_02077	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBMKMC1_02080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynBMKMC1_02081	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynBMKMC1_02083	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynBMKMC1_02084	COG0285	dihydrofolate synthase activity
SynBMKMC1_02085	COG1357	PFAM Pentapeptide repeats (8 copies)
SynBMKMC1_02091	COG4948	Mandelate Racemase Muconate Lactonizing
SynBMKMC1_02092	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBMKMC1_02093	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynBMKMC1_02096	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynBMKMC1_02097	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynBMKMC1_02098	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynBMKMC1_02099	COG4956	integral membrane protein (PIN domain superfamily)
SynBMKMC1_02100	COG0740	serine-type endopeptidase activity
SynBMKMC1_02101	COG0740	serine-type endopeptidase activity
SynBMKMC1_02102	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynBMKMC1_02103	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynBMKMC1_02108	COG0752	glycyl-tRNA synthetase alpha subunit
SynBMKMC1_02110	COG2226	methyltransferase
SynBMKMC1_02112	COG0107	imidazoleglycerol-phosphate synthase activity
SynBMKMC1_02114	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBMKMC1_02115	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynBMKMC1_02116	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynBMKMC1_02116	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynBMKMC1_02118	COG3659	wide pore channel activity
SynBMKMC1_02122	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBMKMC1_02123	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynBMKMC1_02126	COG5002	protein histidine kinase activity
SynBMKMC1_02127	COG2205	protein histidine kinase activity
SynBMKMC1_02132	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_02133	COG5002	protein histidine kinase activity
SynBMKMC1_02136	COG4968	Prepilin-type N-terminal cleavage methylation domain
SynBMKMC1_02139	COG0481	GTPase activity
SynBMKMC1_02140	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynBMKMC1_02142	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynBMKMC1_02143	COG0523	cobalamin synthesis protein
SynBMKMC1_02145	COG1840	ABC-type Fe3 transport system, periplasmic component
SynBMKMC1_02149	COG2271	Major facilitator Superfamily
SynBMKMC1_02151	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynBMKMC1_02157	COG0277	FAD linked oxidase domain protein
SynBMKMC1_02159	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynBMKMC1_02161	COG1666	GTP binding
SynBMKMC1_02164	COG0330	HflC and HflK could
SynBMKMC1_02167	COG0857	belongs to the CobB CobQ family
SynBMKMC1_02169	COG3000	fatty acid hydroxylase
SynBMKMC1_02169	COG0300	oxidoreductase activity
SynBMKMC1_02170	COG0024	Methionine aminopeptidase
SynBMKMC1_02172	COG0335	large ribosomal subunit rRNA binding
SynBMKMC1_02176	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynBMKMC1_02177	COG3263	regulation of cellular component size
SynBMKMC1_02182	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBMKMC1_02183	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynBMKMC1_02186	COG0194	GDP metabolic process
SynBMKMC1_02187	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SynBMKMC1_02188	COG0805	protein transport
SynBMKMC1_02190	COG0723	plastoquinol--plastocyanin reductase activity
SynBMKMC1_02191	COG3258	Cytochrome c
SynBMKMC1_02192	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SynBMKMC1_02193	COG2875	Belongs to the precorrin methyltransferase family
SynBMKMC1_02196	COG0248	Ppx GppA phosphatase
SynBMKMC1_02197	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBMKMC1_02198	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynBMKMC1_02199	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynBMKMC1_02201	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynBMKMC1_02202	COG1028	Short-chain dehydrogenase reductase Sdr
SynBMKMC1_02204	COG0459	protein refolding
SynBMKMC1_02206	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynBMKMC1_02210	COG0109	protoheme IX farnesyltransferase activity
SynBMKMC1_02211	COG1612	heme a metabolic process
SynBMKMC1_02214	COG1845	cytochrome c oxidase, subunit III
SynBMKMC1_02221	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynBMKMC1_02224	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynBMKMC1_02226	COG1007	ATP synthesis coupled electron transport
SynBMKMC1_02227	COG1136	(ABC) transporter
SynBMKMC1_02227	COG0577	efflux transmembrane transporter activity
SynBMKMC1_02228	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_02229	COG0739	heme binding
SynBMKMC1_02230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynBMKMC1_02230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynBMKMC1_02231	COG0436	Aminotransferase
SynBMKMC1_02232	COG3118	belongs to the thioredoxin family
SynBMKMC1_02233	COG1842	Phage shock protein A
SynBMKMC1_02235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SynBMKMC1_02236	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_02237	COG0697	spore germination
SynBMKMC1_02238	COG0616	signal peptide processing
SynBMKMC1_02241	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynBMKMC1_02242	COG0594	ribonuclease P activity
SynBMKMC1_02244	COG0706	membrane insertase activity
SynBMKMC1_02246	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBMKMC1_02248	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynBMKMC1_02249	COG0750	zinc metalloprotease
SynBMKMC1_02250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynBMKMC1_02252	COG1185	polyribonucleotide nucleotidyltransferase activity
SynBMKMC1_02254	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynBMKMC1_02268	COG3415	Transposase
SynBMKMC1_02268	COG2801	Transposase and inactivated derivatives
SynBMKMC1_02326	COG1523	belongs to the glycosyl hydrolase 13 family
SynBMKMC1_02328	COG0776	regulation of translation
SynBMKMC1_02329	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynBMKMC1_02370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SynBMKMC1_02382	COG2234	aminopeptidase activity
SynBMKMC1_02396	COG1715	Restriction endonuclease
SynBMKMC1_02399	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynBMKMC1_02425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBMKMC1_02425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBMKMC1_02428	COG3039	Transposase
SynBMKMC1_02450	COG1061	Type III restriction enzyme res subunit
SynBMKMC1_02463	COG3311	Transcriptional regulator
SynBMKMC1_02464	COG1569	PIN domain
SynBMKMC1_02467	COG2211	Major facilitator Superfamily
SynBMKMC1_02468	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynBMKMC1_02471	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynBMKMC1_02479	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynBMKMC1_02482	COG0284	orotidine-5'-phosphate decarboxylase activity
SynBMKMC1_02486	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynBMKMC1_02491	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynBMKMC1_02494	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBMKMC1_02496	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBMKMC1_02497	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynBMKMC1_02498	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynBMKMC1_02500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynBMKMC1_02502	COG0151	Belongs to the GarS family
SynBMKMC1_02503	COG5002	protein histidine kinase activity
SynBMKMC1_02504	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynBMKMC1_02505	COG4251	negative regulation of phosphorylation
SynBMKMC1_02507	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynBMKMC1_02508	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynBMKMC1_02511	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynBMKMC1_02512	COG0217	transcriptional regulatory protein
SynBMKMC1_02514	COG0363	glucosamine-6-phosphate deaminase activity
SynBMKMC1_02515	COG2385	sporulation resulting in formation of a cellular spore
SynBMKMC1_02516	COG1234	tRNA 3'-trailer cleavage
SynBMKMC1_02517	COG2010	Cytochrome c
SynBMKMC1_02521	COG2264	protein methyltransferase activity
SynBMKMC1_02522	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynBMKMC1_02526	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynBMKMC1_02536	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynBMKMC1_02538	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SynBMKMC1_02540	COG1970	mechanosensitive ion channel activity
SynBMKMC1_02541	COG0459	protein refolding
SynBMKMC1_02542	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynBMKMC1_02544	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynBMKMC1_02545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynBMKMC1_02548	COG0387	Pfam Sodium calcium exchanger
SynBMKMC1_02549	COG0006	proline dipeptidase activity
SynBMKMC1_02550	COG1253	flavin adenine dinucleotide binding
SynBMKMC1_02551	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynBMKMC1_02552	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynBMKMC1_02553	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBMKMC1_02553	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynBMKMC1_02557	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBMKMC1_02559	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBMKMC1_02561	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynBMKMC1_02562	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynBMKMC1_02563	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynBMKMC1_02564	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynBMKMC1_02565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynBMKMC1_02566	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynBMKMC1_02567	COG0356	it plays a direct role in the translocation of protons across the membrane
SynBMKMC1_02569	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBMKMC1_02570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBMKMC1_02574	COG0772	Belongs to the SEDS family
SynBMKMC1_02575	COG4232	protein-disulfide reductase activity
SynBMKMC1_02576	COG1333	cytochrome c biogenesis protein
SynBMKMC1_02577	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynBMKMC1_02581	COG0347	Belongs to the P(II) protein family
SynBMKMC1_02584	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynBMKMC1_02585	COG0114	fumarate hydratase activity
SynBMKMC1_02586	COG4581	dead DEAH box helicase
SynBMKMC1_02587	COG0385	Bile acid
SynBMKMC1_02588	COG0156	8-amino-7-oxononanoate synthase activity
SynBMKMC1_02591	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynBMKMC1_02591	COG4106	trans-aconitate 2-methyltransferase activity
SynBMKMC1_02594	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynBMKMC1_02597	COG0357	Ribosomal RNA small subunit methyltransferase G
SynBMKMC1_02604	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SynBMKMC1_02605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynBMKMC1_02607	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynBMKMC1_02608	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynBMKMC1_02609	COG0085	RNA polymerase activity
SynBMKMC1_02610	COG0084	hydrolase, TatD family'
SynBMKMC1_02611	COG0268	Binds directly to 16S ribosomal RNA
SynBMKMC1_02612	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynBMKMC1_02613	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynBMKMC1_02614	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBMKMC1_02617	COG2197	response regulator
SynBMKMC1_02623	COG0641	radical SAM
SynBMKMC1_02625	COG0779	Required for maturation of 30S ribosomal subunits
SynBMKMC1_02626	COG0195	Participates in both transcription termination and antitermination
SynBMKMC1_02628	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynBMKMC1_02639	COG2988	succinylglutamate desuccinylase activity
SynBMKMC1_02642	COG0488	(ABC) transporter
SynBMKMC1_02646	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynBMKMC1_02647	COG3842	ATPase activity
SynBMKMC1_02648	COG1193	negative regulation of DNA recombination
SynBMKMC1_02651	COG0113	porphobilinogen synthase activity
SynBMKMC1_02652	COG0484	heat shock protein binding
SynBMKMC1_02654	COG0659	secondary active sulfate transmembrane transporter activity
SynBMKMC1_02655	COG0431	NADPH-dependent FMN reductase
SynBMKMC1_02659	COG0300	oxidoreductase activity
SynBMKMC1_02682	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SynBMKMC1_02683	COG0732	type I restriction modification DNA specificity domain
SynBMKMC1_02684	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SynBMKMC1_02687	COG1715	Restriction endonuclease
SynBMKMC1_02690	COG0116	Belongs to the methyltransferase superfamily
SynBMKMC1_02694	COG1196	nuclear chromosome segregation
SynBMKMC1_02697	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBMKMC1_02698	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBMKMC1_02700	COG0439	Biotin carboxylase
SynBMKMC1_02703	COG0515	serine threonine protein kinase
SynBMKMC1_02707	COG4178	(ABC) transporter
SynBMKMC1_02708	COG0537	adenosine 5'-monophosphoramidase activity
SynBMKMC1_02709	COG0606	chelatase, subunit chli
SynBMKMC1_02710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynBMKMC1_02714	COG0242	peptide deformylase activity
SynBMKMC1_02716	COG0235	Class ii aldolase
SynBMKMC1_02717	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynBMKMC1_02720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynBMKMC1_02721	COG0719	Fe-S assembly protein
SynBMKMC1_02722	COG0396	ATPase activity
SynBMKMC1_02723	COG0719	Fe-S assembly protein
SynBMKMC1_02724	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynBMKMC1_02725	COG1830	Aldolase
SynBMKMC1_02729	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBMKMC1_02733	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SynBMKMC1_02737	COG0033	Phosphoglucomutase
SynBMKMC1_02739	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynBMKMC1_02745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBMKMC1_02746	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynBMKMC1_02747	COG0175	sulfate reduction
SynBMKMC1_02748	COG1252	NADH dehydrogenase
SynBMKMC1_02749	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynBMKMC1_02750	COG3273	potassium ion transport
SynBMKMC1_02750	COG0471	metal ion transport
SynBMKMC1_02751	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynBMKMC1_02752	COG0569	domain protein
SynBMKMC1_02753	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynBMKMC1_02759	COG0488	(ABC) transporter
SynBMKMC1_02761	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBMKMC1_02764	COG1643	Atp-dependent helicase
SynBMKMC1_02765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBMKMC1_02767	COG1570	exodeoxyribonuclease VII activity
SynBMKMC1_02768	COG1722	exodeoxyribonuclease VII activity
SynBMKMC1_02779	COG0483	inositol monophosphate 1-phosphatase activity
SynBMKMC1_02782	COG1968	undecaprenyl-diphosphatase activity
SynBMKMC1_02784	COG1555	photosystem II stabilization
SynBMKMC1_02785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynBMKMC1_02787	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBMKMC1_02790	COG1032	radical SAM domain protein
SynBMKMC1_02796	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynBMKMC1_02801	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynBMKMC1_02803	COG0463	Glycosyl transferase, family 2
SynBMKMC1_02804	COG1587	Uroporphyrinogen-III synthase
SynBMKMC1_02807	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBMKMC1_02808	COG0316	Belongs to the HesB IscA family
SynBMKMC1_02811	COG1090	epimerase
SynBMKMC1_02815	COG0484	heat shock protein binding
SynBMKMC1_02816	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynBMKMC1_02817	COG3659	wide pore channel activity
SynBMKMC1_02818	COG3659	wide pore channel activity
SynBMKMC1_02826	COG1122	ATPase activity
SynBMKMC1_02828	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_02830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynBMKMC1_02831	COG2217	Heavy metal translocating P-type atpase
SynBMKMC1_02832	COG3063	Type IV pilus biogenesis stability protein PilW
SynBMKMC1_02833	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynBMKMC1_02835	COG0416	fatty acid biosynthetic process
SynBMKMC1_02836	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynBMKMC1_02837	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynBMKMC1_02840	COG1214	PFAM Peptidase M22, glycoprotease
SynBMKMC1_02842	COG0617	tRNA 3'-terminal CCA addition
SynBMKMC1_02844	COG1562	ergosterol biosynthetic process
SynBMKMC1_02845	COG0493	'glutamate synthase
SynBMKMC1_02845	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBMKMC1_02848	COG0583	DNA-binding transcription factor activity
SynBMKMC1_02850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynBMKMC1_02851	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_02853	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynBMKMC1_02858	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynBMKMC1_02859	COG0713	ATP synthesis coupled electron transport
SynBMKMC1_02860	COG0839	Belongs to the complex I subunit 6 family
SynBMKMC1_02861	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBMKMC1_02862	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynBMKMC1_02863	COG0372	Belongs to the citrate synthase family
SynBMKMC1_02864	COG2062	phosphohistidine phosphatase, SixA
SynBMKMC1_02867	COG1420	regulation of RNA biosynthetic process
SynBMKMC1_02869	COG0133	tryptophan synthase activity
SynBMKMC1_02870	COG2226	methyltransferase
SynBMKMC1_02871	COG0023	Translation Initiation Factor
SynBMKMC1_02872	COG0529	Catalyzes the synthesis of activated sulfate
SynBMKMC1_02873	COG0628	permease
SynBMKMC1_02874	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynBMKMC1_02876	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBMKMC1_02878	COG0564	pseudouridine synthase activity
SynBMKMC1_02879	COG0745	RESPONSE REGULATOR receiver
SynBMKMC1_02881	COG1104	cysteine desulfurase activity
SynBMKMC1_02883	COG0275	rRNA processing
SynBMKMC1_02884	COG0649	NAD binding
SynBMKMC1_02885	COG0824	Thioesterase
SynBMKMC1_02888	COG1575	Belongs to the MenA family. Type 1 subfamily
SynBMKMC1_02890	COG0189	ligase activity
SynBMKMC1_02891	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynBMKMC1_02894	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynBMKMC1_02896	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynBMKMC1_02897	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynBMKMC1_02898	COG0512	Glutamine amidotransferase of anthranilate synthase
SynBMKMC1_02900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynBMKMC1_02905	COG0252	asparaginase activity
SynBMKMC1_02907	COG0018	arginyl-trna synthetase
SynBMKMC1_02908	COG0157	Belongs to the NadC ModD family
SynBMKMC1_02911	COG0242	peptide deformylase activity
SynBMKMC1_02912	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynBMKMC1_02915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynBMKMC1_02916	COG4172	Belongs to the ABC transporter superfamily
SynBMKMC1_02920	COG0564	pseudouridine synthase activity
SynBMKMC1_02922	COG0589	response to stress
SynBMKMC1_02923	COG0126	phosphoglycerate kinase activity
SynBMKMC1_02925	COG2084	Dehydrogenase
SynBMKMC1_02927	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynBMKMC1_02928	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynBMKMC1_02934	COG0167	dihydroorotate dehydrogenase activity
SynBMKMC1_02937	COG0222	ribosome binding
SynBMKMC1_02938	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynBMKMC1_02939	COG0081	regulation of translation
SynBMKMC1_02940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynBMKMC1_02941	COG0250	Participates in transcription elongation, termination and antitermination
SynBMKMC1_02942	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynBMKMC1_02943	COG0542	response to heat
SynBMKMC1_02945	COG0148	phosphopyruvate hydratase activity
SynBMKMC1_02946	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBMKMC1_02950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynBMKMC1_02951	COG0237	dephospho-CoA kinase activity
SynBMKMC1_02952	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynBMKMC1_02953	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynBMKMC1_02953	COG2022	thiamine diphosphate biosynthetic process
SynBMKMC1_02955	COG0105	UTP biosynthetic process
SynBMKMC1_02957	COG1166	arginine decarboxylase activity
SynBMKMC1_02960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynBMKMC1_02962	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynBMKMC1_02968	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBMKMC1_02968	COG0426	domain, Protein
SynBMKMC1_02969	COG0426	domain, Protein
SynBMKMC1_02969	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBMKMC1_02971	COG1741	Belongs to the pirin family
SynBMKMC1_02977	COG0509	glycine decarboxylation via glycine cleavage system
SynBMKMC1_02978	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynBMKMC1_02982	COG0359	binds to the 23S rRNA
SynBMKMC1_02983	COG0305	Participates in initiation and elongation during chromosome replication
SynBMKMC1_02983	COG1372	Participates in initiation and elongation during chromosome replication
SynBMKMC1_02983	COG0305	Participates in initiation and elongation during chromosome replication
SynBMKMC1_02983	COG1372	Participates in initiation and elongation during chromosome replication
SynBMKMC1_02984	COG0445	tRNA wobble uridine modification
SynBMKMC1_02993	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynBMKMC1_02996	COG0398	Pfam SNARE associated Golgi protein
SynBMKMC1_02999	COG0668	transmembrane transport
SynBMKMC1_03003	COG0525	valine-tRNA ligase activity
SynBMKMC1_03005	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynBMKMC1_03005	COG3264	Mechanosensitive ion channel
SynBMKMC1_03009	COG4221	oxidoreductase activity
SynBMKMC1_03016	COG3956	TIGRFAM MazG family protein
SynBMKMC1_03019	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynBMKMC1_03022	COG0010	Belongs to the arginase family
SynBMKMC1_03025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynBMKMC1_03026	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynBMKMC1_03027	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_03028	COG0783	Belongs to the Dps family
SynBMKMC1_03029	COG0504	CTP synthase activity
SynBMKMC1_03030	COG0602	queuosine metabolic process
SynBMKMC1_03032	COG4942	peptidase
SynBMKMC1_03033	COG4574	serine-type endopeptidase inhibitor activity
SynBMKMC1_03034	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynBMKMC1_03035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynBMKMC1_03037	COG0531	amino acid
SynBMKMC1_03039	COG0366	Alpha amylase catalytic
SynBMKMC1_03040	COG0463	Glycosyl transferase, family 2
SynBMKMC1_03047	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynBMKMC1_03048	COG0830	nickel cation binding
SynBMKMC1_03049	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynBMKMC1_03050	COG0829	nickel cation binding
SynBMKMC1_03051	COG0831	urea catabolic process
SynBMKMC1_03052	COG0832	Belongs to the urease beta subunit family
SynBMKMC1_03053	COG0804	urea catabolic process
SynBMKMC1_03058	COG0367	asparagine synthase
SynBMKMC1_03059	COG0540	Belongs to the ATCase OTCase family
SynBMKMC1_03063	COG2308	Evidence 4 Homologs of previously reported genes of
SynBMKMC1_03067	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynBMKMC1_03068	COG0746	molybdenum cofactor guanylyltransferase activity
SynBMKMC1_03069	COG2223	nitrite transmembrane transporter activity
SynBMKMC1_03070	COG0243	molybdopterin cofactor binding
SynBMKMC1_03075	COG0315	cyclic pyranopterin monophosphate synthase activity
SynBMKMC1_03076	COG0303	'Molybdopterin
SynBMKMC1_03077	COG0314	molybdopterin synthase activity
SynBMKMC1_03078	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SynBMKMC1_03079	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynBMKMC1_03080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynBMKMC1_03083	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynBMKMC1_03085	COG2116	formate transmembrane transporter activity
SynBMKMC1_03087	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynBMKMC1_03089	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynBMKMC1_03092	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynBMKMC1_03093	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBMKMC1_03094	COG0170	dolichyl monophosphate biosynthetic process
SynBMKMC1_03096	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynBMKMC1_03097	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynBMKMC1_03101	COG0788	formyltetrahydrofolate deformylase activity
SynBMKMC1_03104	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynBMKMC1_03106	COG0443	Heat shock 70 kDa protein
SynBMKMC1_03107	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynBMKMC1_03109	COG0360	Binds together with S18 to 16S ribosomal RNA
SynBMKMC1_03111	COG0137	argininosuccinate synthase activity
SynBMKMC1_03114	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynBMKMC1_03118	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynBMKMC1_03119	COG0438	transferase activity, transferring glycosyl groups
SynBMKMC1_03121	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynBMKMC1_03122	COG0497	DNA recombination
SynBMKMC1_03123	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBMKMC1_03125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SynBMKMC1_50007	COG1454	alcohol dehydrogenase
SynBMKMC1_50010	COG2197	response regulator