locus-tag	class	description
sync_0001	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
sync_0003	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
sync_0004	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
sync_0007	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
sync_0010	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
sync_0012	ENOG4107SGM	protein serine threonine phosphatase
sync_0013	ENOG4105CH7	arginosuccinase
sync_0014	ENOG4105VFU	Rna-binding protein
sync_0016	ENOG4105E0X	reductase
sync_0017	ENOG4105CBX	hi0933 family
sync_0020	ENOG4105CZX	twitching motility protein
sync_0021	ENOG4107QHF	type ii secretion system protein e
sync_0022	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
sync_0023	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
sync_0025	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
sync_0026	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
sync_0027	ENOG4105D4A	Cell wall formation (By similarity)
sync_0028	ENOG4105DFU	Cell wall formation (By similarity)
sync_0030	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
sync_0032	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
sync_0033	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
sync_0034	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
sync_0046	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
sync_0047	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
sync_0051	ENOG4105CJN	penicillin-binding protein
sync_0052	ENOG4105BZF	Glycosyl transferase (Group 1
sync_0053	ENOG4105CMR	udp-glucose 4-epimerase
sync_0055	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
sync_0058	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
sync_0059	ENOG41084A0	50s ribosomal protein L35
sync_0060	ENOG4105JFG	SpoIID LytB domain protein
sync_0062	ENOG4105C6E	dna polymerase iii
sync_0064	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
sync_0065	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
sync_0066	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
sync_0067	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
sync_0068	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
sync_0071	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
sync_0074	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
sync_0079	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
sync_0080	ENOG4106YF5	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
sync_0081	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
sync_0085	ENOG4105E2K	Glycosyl transferase (Group 1
sync_0086	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
sync_0087	ENOG4105D7W	serine acetyltransferase
sync_0088	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
sync_0090	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
sync_0091	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
sync_0094	ENOG41086BQ	Protein CrcB homolog
sync_0095	ENOG4107KCI	Protein CrcB homolog
sync_0097	ENOG4105CJW	magnesium transporter
sync_0098	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_0099	ENOG4108YIQ	Alpha beta hydrolase
sync_0100	ENOG4105BZS	acriflavin resistance protein
sync_0101	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
sync_0102	ENOG4105CEN	a g-specific adenine glycosylase
sync_0103	ENOG4105D7K	pfkb domain protein
sync_0105	ENOG4105C5F	glutamine synthetase
sync_0106	ENOG4107QN1	sodium solute
sync_0108	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
sync_0109	ENOG4107T5V	SNARE associated Golgi
sync_0112	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
sync_0116	ENOG4105CRK	lysyL-tRNA synthetase
sync_0120	ENOG41067HS	methyltransferase
sync_0123	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
sync_0124	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
sync_0129	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
sync_0130	ENOG4105CV1	Transketolase (EC 2.2.1.1)
sync_0132	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
sync_0133	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
sync_0134	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
sync_0145	ENOG4105C30	Nad-dependent epimerase dehydratase
sync_0149	ENOG4105DAY	polysaccharide export protein
sync_0150	ENOG4107YJ4	chain length determinant protein
sync_0151	ENOG41077RS	Phosphatase
sync_0169	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
sync_0170	ENOG4105F0R	Cytidylyltransferase
sync_0172	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
sync_0174	ENOG4105D2T	synthase
sync_0176	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
sync_0178	ENOG4105CAQ	asparagine synthetase
sync_0179	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
sync_0183	ENOG4105D3Q	Sugar transferase
sync_0187	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
sync_0195	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
sync_0197	ENOG4105EYW	Ion transport protein
sync_0200	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
sync_0202	ENOG41084W5	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
sync_0210	ENOG4105EU8	FAD linked oxidase domain protein
sync_0213	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
sync_0214	ENOG4108HMX	isocitrate dehydrogenase (NADP)
sync_0219	ENOG4105BZ1	(ABC) transporter
sync_0220	ENOG4107EF8	Glycosyl transferase (Group 1
sync_0221	ENOG4108KMV	Glycosyl transferase (Group 1
sync_0222	ENOG4105CG5	Glycosyl transferase (Group 1
sync_0223	ENOG4107T8Q	Glycosyl transferase (Group 1
sync_0228	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
sync_0230	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
sync_0231	ENOG4105CMR	udp-glucose 4-epimerase
sync_0232	ENOG4105CUT	histidyl-tRNA synthetase
sync_0233	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
sync_0236	ENOG4105YEU	This protein is a component of the reaction center of photosystem II (By similarity)
sync_0237	ENOG4107JBH	Required for PSII activity (By similarity)
sync_0238	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
sync_0239	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
sync_0240	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
sync_0241	ENOG410828V	rubredoxin
sync_0242	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
sync_0243	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
sync_0244	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
sync_0245	ENOG4105CHW	UPF0052 protein
sync_0246	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
sync_0247	ENOG4107PE3	Mammalian cell entry related domain protein
sync_0248	ENOG4105EET	magnesium chelatase
sync_0251	ENOG4108YZ4	nudix hydrolase
sync_0252	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
sync_0258	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
sync_0259	ENOG4105FFC	UPF0187 protein
sync_0260	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
sync_0263	ENOG41062D9	Histidine kinase
sync_0265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
sync_0272	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
sync_0273	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
sync_0275	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
sync_0279	ENOG4105C37	(CBS) domain
sync_0283	ENOG4106815	This protein is a component of the reaction center of photosystem II (By similarity)
sync_0284	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
sync_0285	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
sync_0289	ENOG4105DC1	bifunctional purine biosynthesis protein purh
sync_0292	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
sync_0294	ENOG4105PW4	Sugar fermentation stimulation protein homolog
sync_0300	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
sync_0301	ENOG4105ESV	Glycosyl transferase, family 4
sync_0302	ENOG4105CEV	competence damage-inducible protein
sync_0303	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
sync_0307	ENOG4106A1F	This protein is a component of the reaction center of photosystem II (By similarity)
sync_0309	ENOG410686T	photosystem II reaction center protein N
sync_0310	ENOG4105WIA	photosystem II reaction center protein H
sync_0311	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
sync_0312	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
sync_0315	ENOG4108R0D	protein with myosin-like
sync_0317	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
sync_0319	ENOG4105DHP	deoxycytidine triphosphate deaminase
sync_0321	ENOG4108S64	thioredoxin-like protein txlA
sync_0323	ENOG4107SC1	transglycosylase
sync_0325	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
sync_0328	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
sync_0333	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
sync_0337	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
sync_0342	ENOG4108VX5	3-methyladenine DNA glycosylase
sync_0343	ENOG4105CXT	aspartate transcarbamylase
sync_0353	ENOG4105CPJ	photosystem II manganese-stabilizing
sync_0354	ENOG4107RIQ	Sulfate adenylate transferase
sync_0358	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
sync_0360	ENOG4105C3Q	Glycosyl transferase, family 2
sync_0361	ENOG4107QW3	Sucrose phosphorylase
sync_0364	ENOG4108DJF	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
sync_0368	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
sync_0369	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
sync_0371	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
sync_0372	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
sync_0375	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
sync_0377	ENOG4105CQC	Prephenate dehydratase
sync_0379	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
sync_0380	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
sync_0381	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
sync_0382	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
sync_0383	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
sync_0384	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
sync_0389	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
sync_0391	ENOG4105E4R	Precorrin-3B C17-methyltransferase
sync_0393	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
sync_0394	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
sync_0396	ENOG4105ECK	Fatty Acid Desaturase
sync_0398	ENOG4108W6I	photosystem I reaction center protein subunit XI
sync_0401	ENOG4105CKK	Glycosyl transferase, family 2
sync_0406	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
sync_0408	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
sync_0409	ENOG41082HT	Binds the 23S rRNA (By similarity)
sync_0410	ENOG4108UJD	30S ribosomal protein S9
sync_0411	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
sync_0412	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
sync_0413	ENOG4108ZT0	50S ribosomal protein l17
sync_0414	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
sync_0415	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
sync_0416	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
sync_0417	ENOG41067V7	50S ribosomal protein L36
sync_0418	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
sync_0419	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
sync_0420	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
sync_0421	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
sync_0422	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
sync_0423	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
sync_0424	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
sync_0425	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
sync_0426	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
sync_0427	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
sync_0428	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
sync_0429	ENOG410848H	50s ribosomal protein l29
sync_0430	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
sync_0431	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
sync_0432	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
sync_0433	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
sync_0434	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
sync_0435	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
sync_0436	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
sync_0437	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
sync_0438	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
sync_0440	ENOG4105CD2	stage iii sporulation protein aa
sync_0443	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
sync_0447	ENOG4105EVN	Prephenate dehydrogenase
sync_0453	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
sync_0455	ENOG4105CVK	Glutamate decarboxylase
sync_0456	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
sync_0457	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
sync_0460	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
sync_0465	ENOG4105CNI	cell division protein FtsW
sync_0467	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
sync_0476	ENOG4105EYW	Ion transport protein
sync_0479	ENOG4108FN7	Aldo keto reductase
sync_0481	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
sync_0483	ENOG4105CAT	Cytidine monophosphate kinase
sync_0490	ENOG4108KKY	Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin (By similarity)
sync_0509	ENOG4108RYV	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
sync_0510	ENOG4108U42	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
sync_0511	ENOG4108MZQ	phycobilisome linker polypeptide
sync_0515	ENOG4106BTU	phycobilisome rod-core linker polypeptide
sync_0528	ENOG4107S5T	Carbohydrate kinase
sync_0529	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
sync_0531	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
sync_0532	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
sync_0534	ENOG4105YVZ	photosystem II
sync_0540	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
sync_0541	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
sync_0544	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
sync_0546	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
sync_0547	ENOG4105DCI	Phosphohydrolase
sync_0548	ENOG4105CN1	protease
sync_0549	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
sync_0550	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
sync_0559	ENOG4105CHH	sulfate transporter
sync_0561	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
sync_0562	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
sync_0564	ENOG4105C9U	ATP-dependent DNA helicase RecQ
sync_0566	ENOG4105C26	Dehydrogenase
sync_0568	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
sync_0569	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
sync_0578	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
sync_0586	ENOG4105WH1	Two component transcriptional regulator luxr family
sync_0589	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
sync_0590	ENOG4105DVK	Precorrin-2 c20-methyltransferase
sync_0592	ENOG4107QZ7	Cellulose synthase catalytic subunit
sync_0595	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
sync_0596	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
sync_0597	ENOG4107U45	Cobalt transport protein
sync_0599	ENOG4105DFA	alanine racemase domain protein
sync_0600	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
sync_0602	ENOG4108KMV	Glycosyl transferase (Group 1
sync_0604	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
sync_0605	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
sync_0607	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
sync_0608	ENOG4108IQE	Amp-dependent synthetase and ligase
sync_0618	ENOG4105C0X	amino acid
sync_0619	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
sync_0620	ENOG4105C6T	cysteine synthase
sync_0629	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
sync_0630	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
sync_0632	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
sync_0636	ENOG4105C3J	Cysteine desulfurase
sync_0647	ENOG41083MR	nifu domain-containing protein
sync_0648	ENOG4105DWT	malate dehydrogenase (quinone)
sync_0649	ENOG4105DCT	glycerol dehydrogenase
sync_0651	ENOG410814C	multidrug resistance protein
sync_0652	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
sync_0659	ENOG4106855	Competence protein
sync_0669	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
sync_0675	ENOG4105BZU	Histidine kinase
sync_0678	ENOG4108PWY	Carbohydrate-selective porin OprB
sync_0680	ENOG41090A1	ferritin
sync_0686	ENOG4105PGM	cation diffusion facilitator family transporter
sync_0690	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
sync_0693	ENOG41080UX	Methyltransferase
sync_0695	ENOG4108JQC	penicillin-binding protein 1A
sync_0696	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
sync_0698	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
sync_0700	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
sync_0706	ENOG4105BZU	Histidine kinase
sync_0717	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
sync_0723	ENOG4105D3Q	Sugar transferase
sync_0724	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
sync_0725	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
sync_0727	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
sync_0730	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
sync_0731	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
sync_0734	ENOG4105CPF	Cell wall formation (By similarity)
sync_0735	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
sync_0736	ENOG4105DTQ	mandelate racemase muconate lactonizing
sync_0743	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
sync_0744	ENOG4105C8Y	Acetylornithine aminotransferase
sync_0746	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
sync_0751	ENOG4105DK0	Indole-3-glycerol phosphate synthase
sync_0754	ENOG4105C3F	Signal peptidase i
sync_0756	ENOG4108V1T	peptidylprolyl cis-trans isomerase
sync_0758	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
sync_0759	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
sync_0760	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
sync_0761	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_0763	ENOG4105DGU	Histone deacetylase
sync_0764	ENOG4108JYK	Dehydrogenase
sync_0766	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
sync_0767	ENOG41082B1	30S ribosomal protein S16
sync_0772	ENOG4107FQX	Alpha-acetolactate decarboxylase
sync_0773	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
sync_0775	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
sync_0781	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
sync_0783	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
sync_0786	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
sync_0791	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
sync_0793	ENOG4105DTN	riboflavin biosynthesis protein ribF
sync_0795	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
sync_0796	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
sync_0806	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
sync_0807	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
sync_0811	ENOG4105ECQ	AraC Family Transcriptional Regulator
sync_0826	ENOG4105DBV	ornithine carbamoyltransferase
sync_0827	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
sync_0860	ENOG4105CHR	reductase
sync_0861	ENOG4105CXK	mandelate racemase muconate lactonizing
sync_0872	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
sync_0874	ENOG4105VGQ	Photosystem I subunit X
sync_0878	ENOG4105CSH	Transporter
sync_0893	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
sync_0895	ENOG4108Z03	MAF-like protein
sync_0897	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
sync_0898	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
sync_0901	ENOG41081E8	Alpha beta hydrolase
sync_0907	ENOG4108R99	pseudouridine synthase
sync_0909	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
sync_0910	ENOG4105C3M	thioredoxin reductase
sync_0915	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
sync_0916	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
sync_0917	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
sync_0920	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
sync_0921	ENOG4105C8J	)-transporter
sync_0924	ENOG4105C8N	cysteinyl-tRNA synthetase
sync_0929	ENOG4105D0S	secretion protein (HlyD
sync_0930	ENOG4105C3G	gtp-binding protein
sync_0938	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
sync_0948	ENOG4108V9Q	carbonic anhydrase
sync_0961	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
sync_0964	ENOG4108J4B	Beta-lactamase
sync_0965	ENOG4106FVC	RNA methyltransferase
sync_0967	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
sync_0969	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
sync_0970	ENOG4105K63	Thioredoxin
sync_0971	ENOG4107QVP	Dehydrogenase
sync_0974	ENOG4108JT6	LycopEne
sync_0976	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
sync_0977	ENOG4105DRS	transport system, permease
sync_0988	ENOG4105D3G	Pseudouridine synthase
sync_0990	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
sync_0991	ENOG4105CTB	Polyprenyl synthetase
sync_0998	ENOG4108ZM9	phosphoglycerate mutase
sync_0999	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
sync_1000	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
sync_1001	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
sync_1003	ENOG4107SC0	ferredoxin--NADP reductase
sync_1006	ENOG4105BZU	Histidine kinase
sync_1009	ENOG4105CD8	aminopeptidase N
sync_1011	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
sync_1018	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_1022	ENOG4105CXN	decarboxylase
sync_1025	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
sync_1027	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
sync_1028	ENOG410801F	ribosomal-protein-alanine acetyltransferase
sync_1030	ENOG4105C8B	TIGR00159 family
sync_1031	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
sync_1032	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
sync_1034	ENOG4105C72	UPF0176 protein
sync_1037	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
sync_1038	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
sync_1044	ENOG4108RCF	TRANSCRIPTIONal
sync_1046	ENOG4105BZ1	(ABC) transporter
sync_1048	ENOG4105VFU	Rna-binding protein
sync_1051	ENOG4105C1J	atp-dependent rna helicase
sync_1052	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
sync_1053	ENOG4107QYX	exodeoxyribonuclease v alpha
sync_1054	ENOG4107QKA	exodeoxyribonuclease V beta
sync_1055	ENOG4105DSY	exodeoxyribonuclease V, gamma
sync_1056	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
sync_1059	ENOG4105C09	Bile acid
sync_1089	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
sync_1133	ENOG4105EB3	Histidine kinase
sync_1134	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
sync_1136	ENOG4108Z0R	Transferase
sync_1137	ENOG41076WT	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II (By similarity)
sync_1138	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
sync_1151	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
sync_1161	ENOG4105CYM	Glutathione S-transferase
sync_1169	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
sync_1172	ENOG4105CYM	Glutathione S-transferase
sync_1181	ENOG4105CVG	Homoserine O-transsuccinylase
sync_1186	ENOG4105CDA	abc transporter atp-binding protein
sync_1187	ENOG4105DRP	amino acid AbC transporter
sync_1189	ENOG4105EZ7	amino acid ABC transporter
sync_1191	ENOG4105CHH	sulfate transporter
sync_1195	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
sync_1204	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
sync_1206	ENOG4105BZG	amino acid carrier protein
sync_1208	ENOG4105BZ1	(ABC) transporter
sync_1210	ENOG4105CP7	Triose-phosphate isomerase
sync_1215	ENOG4105BZ1	(ABC) transporter
sync_1219	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
sync_1220	ENOG4105CTK	cobaltochelatase, cobn subunit
sync_1221	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
sync_1223	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_1224	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
sync_1226	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
sync_1232	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
sync_1234	ENOG4105CSR	polyphosphate kinase 2
sync_1238	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_1249	ENOG4106BTU	phycobilisome rod-core linker polypeptide
sync_1260	ENOG4105QNJ	serralysin (EC 3.4.24.40)
sync_1263	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_1265	ENOG4108IAX	Ribonucleoside-triphosphate reductase
sync_1268	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
sync_1269	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
sync_1272	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
sync_1273	ENOG4108JJB	ABC transporter
sync_1275	ENOG4105CE9	30S ribosomal protein S2
sync_1276	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
sync_1281	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
sync_1284	ENOG4105CFP	Peptidase U32
sync_1288	ENOG4108IUZ	ABC transporter
sync_1290	ENOG4105CRE	cytochrome C
sync_1295	ENOG4107TS3	membrane protein, TerC
sync_1300	ENOG4105C1J	atp-dependent rna helicase
sync_1301	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
sync_1304	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
sync_1315	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
sync_1316	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
sync_1319	ENOG41068G9	50S ribosomal protein L32
sync_1321	ENOG4105DJZ	UPF0182 protein
sync_1325	ENOG4105DR5	peptidase
sync_1328	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
sync_1337	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
sync_1338	ENOG41084GG	50S ribosomal protein L33
sync_1339	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
sync_1340	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
sync_1347	ENOG4105JFG	SpoIID LytB domain protein
sync_1355	ENOG4105CTK	cobaltochelatase, cobn subunit
sync_1357	ENOG4105DB7	PHP domain protein
sync_1359	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
sync_1361	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
sync_1362	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
sync_1367	ENOG4107QI6	Cysteine desulfurase
sync_1368	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
sync_1375	ENOG4105C8T	Leucyl-tRNA synthetase
sync_1376	ENOG4105C89	phosphohexose isomerase
sync_1381	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
sync_1382	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
sync_1384	ENOG4108ZCU	PPIases accelerate the folding of proteins
sync_1385	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
sync_1386	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
sync_1388	ENOG4105DVC	DnaJ domain protein
sync_1390	ENOG4105C8U	phosphate abc transporter
sync_1391	ENOG4105E2Z	phosphate ABC transporter (Permease
sync_1392	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
sync_1396	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
sync_1398	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
sync_1399	ENOG41083EU	50s ribosomal protein l28
sync_1400	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
sync_1402	ENOG4107T3P	ABC, transporter
sync_1405	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
sync_1409	ENOG4105VGQ	Photosystem I subunit X
sync_1410	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
sync_1411	ENOG4105C7B	Threonine dehydratase
sync_1413	ENOG4108VIA	integral membrane protein
sync_1416	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
sync_1418	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
sync_1419	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
sync_1423	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
sync_1424	ENOG4105SS7	PucC protein
sync_1428	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
sync_1429	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
sync_1430	ENOG4105D49	3-dehydroquinate synthase
sync_1436	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
sync_1437	ENOG4107T0X	DNA ligase
sync_1438	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
sync_1439	ENOG4107QRT	dEAD DEAH box helicase
sync_1452	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
sync_1456	ENOG4108535	NAD dependent epimerase/dehydratase family
sync_1457	ENOG4105JZI	cytochrome P450
sync_1458	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
sync_1459	ENOG4107QN2	dihydrolipoyl dehydrogenase
sync_1465	ENOG4107QZ7	Cellulose synthase catalytic subunit
sync_1467	ENOG4106R7G	Glycoside hydrolase family 5
sync_1472	ENOG4108JUB	Transcriptional regulator
sync_1489	ENOG4107R16	Multicopper oxidase
sync_1491	ENOG4107RA9	decarboxylase
sync_1496	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
sync_1497	ENOG4105CC5	ABC transporter
sync_1498	ENOG4105FDK	ABC transporter
sync_1499	ENOG4105DSE	periplasmic solute binding protein
sync_1500	ENOG4108PWY	Carbohydrate-selective porin OprB
sync_1501	ENOG4108PWY	Carbohydrate-selective porin OprB
sync_1508	ENOG4105CKI	cobalamin synthesis protein
sync_1512	ENOG4105BZU	Histidine kinase
sync_1514	ENOG4105BZU	Histidine kinase
sync_1515	ENOG4105CEY	Amp-dependent synthetase and ligase
sync_1522	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
sync_1526	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
sync_1527	ENOG4108IPT	Naphthoate synthase
sync_1528	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
sync_1529	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
sync_1533	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
sync_1537	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
sync_1538	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
sync_1542	ENOG4108PWY	Carbohydrate-selective porin OprB
sync_1544	ENOG4107E2E	PKHD-type hydroxylase
sync_1545	ENOG4107QKW	extracellular solute-binding protein family 1
sync_1547	ENOG4108N5B	2-phosphosulfolactate phosphatase
sync_1549	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
sync_1550	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
sync_1552	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
sync_1553	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
sync_1556	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
sync_1557	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
sync_1561	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
sync_1562	ENOG4105BZ4	penicillin-binding protein
sync_1565	ENOG4108Z6B	deaminase
sync_1566	ENOG4105C5R	Aminotransferase
sync_1567	ENOG4108TCG	allophycocyanin beta subunit
sync_1569	ENOG4105C5F	glutamine synthetase
sync_1576	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
sync_1582	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
sync_1583	ENOG4105MSA	Photosystem II reaction center W protein
sync_1584	ENOG4105DSF	transport protein
sync_1588	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
sync_1589	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
sync_1593	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
sync_1594	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
sync_1596	ENOG4107JDS	UPF0102 protein
sync_1600	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
sync_1606	ENOG4105KT5	UmuD protein
sync_1607	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
sync_1608	ENOG41061H0	Monooxygenase
sync_1613	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
sync_1627	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
sync_1628	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
sync_1631	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
sync_1634	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
sync_1635	ENOG4105WN5	stage II sporulation protein
sync_1636	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
sync_1637	ENOG4108I0Q	anthranilate phosphoribosyltransferase
sync_1638	ENOG4105BZ1	(ABC) transporter
sync_1640	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
sync_1659	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
sync_1661	ENOG4107R51	Glycosyl transferase, family 2
sync_1665	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_1669	ENOG4105D5T	phosphonate abc transporter
sync_1670	ENOG4107T9Q	phosphonate abc transporter
sync_1673	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
sync_1674	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
sync_1685	ENOG4105CBT	Fructose-1,6-bisphosphatase
sync_1686	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
sync_1687	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
sync_1688	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
sync_1692	ENOG4105C01	Dihydroxy-acid dehydratase
sync_1694	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
sync_1696	ENOG4107QRP	cobalamin biosynthesis protein CobW
sync_1701	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
sync_1704	ENOG4107R1Y	fructose-bisphosphate aldolase
sync_1707	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
sync_1711	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
sync_1712	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
sync_1713	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
sync_1714	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
sync_1723	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
sync_1726	ENOG41080XP	Cbs domain
sync_1728	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
sync_1734	ENOG4107PBV	potassium channel
sync_1742	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
sync_1747	ENOG4107SIG	periplasmic solute binding protein
sync_1748	ENOG4105CC5	ABC transporter
sync_1749	ENOG4105DIK	(ABC) transporter
sync_1752	ENOG4108PJD	permease
sync_1753	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
sync_1771	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
sync_1801	ENOG4107GJV	short-chain dehydrogenase reductase
sync_1803	ENOG4107CUI	carotenoid binding protein
sync_1818	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_1834	ENOG4105FFC	UPF0187 protein
sync_1844	ENOG4105EWK	phytoene
sync_1850	ENOG4105CSM	endonuclease III
sync_1851	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_1856	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
sync_1858	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
sync_1863	ENOG4105C31	Tryptophanyl-tRNA synthetase
sync_1866	ENOG4105C22	threonyL-tRNA synthetase
sync_1868	ENOG4105CHC	glucokinase (EC 2.7.1.2)
sync_1869	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
sync_1870	ENOG4105C8S	subunit m
sync_1871	ENOG4105DGW	oligopeptidase A
sync_1878	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
sync_1879	ENOG4105DKQ	ROK family
sync_1886	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
sync_1887	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
sync_1889	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
sync_1890	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
sync_1897	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
sync_1899	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
sync_1902	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_1910	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
sync_1912	ENOG41069EW	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
sync_1918	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
sync_1922	ENOG4105EKE	dihydroorotase
sync_1923	ENOG4105CHH	sulfate transporter
sync_1931	ENOG4105DC8	reductase
sync_1933	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
sync_1934	ENOG4105C0H	protease
sync_1937	ENOG4107WJM	-acetyltransferase
sync_1939	ENOG4105BZ1	(ABC) transporter
sync_1940	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
sync_1941	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
sync_1945	ENOG4106F1P	AAA ATPase, central domain protein
sync_1951	ENOG4105C3M	thioredoxin reductase
sync_1958	ENOG4105C8S	subunit m
sync_1959	ENOG4105D65	subunit l
sync_1960	ENOG4105KNY	Microcompartments protein
sync_1966	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
sync_1967	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
sync_1968	ENOG4105KNY	Microcompartments protein
sync_1973	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
sync_1974	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
sync_1975	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
sync_1982	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
sync_1984	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
sync_1986	ENOG4105EUJ	GTP cyclohydrolase i
sync_1988	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
sync_1989	ENOG4105E6N	shikimate quinate 5-dehydrogenase
sync_1990	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
sync_1993	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
sync_1995	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
sync_1996	ENOG4105DZ0	fad dependent oxidoreductase
sync_1999	ENOG4105C7K	acetolactate synthase
sync_2000	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_2003	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
sync_2004	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
sync_2005	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
sync_2007	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
sync_2008	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
sync_2009	ENOG4105CJN	penicillin-binding protein
sync_2012	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
sync_2016	ENOG4105KUZ	arsenate reductase
sync_2018	ENOG4105F0N	pyrophosphate phospho-hydrolase
sync_2021	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
sync_2023	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
sync_2029	ENOG4105CAS	nag kinase
sync_2032	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_2036	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
sync_2039	ENOG4105F0N	pyrophosphate phospho-hydrolase
sync_2040	ENOG4105CTD	carboxy-peptidase
sync_2044	ENOG4105KZX	Pterin carbinolamine dehydratase
sync_2045	ENOG4105CKI	cobalamin synthesis protein
sync_2051	ENOG4105C8M	UPF0272 protein
sync_2056	ENOG4105CGK	Exodeoxyribonuclease III
sync_2057	ENOG4105CQB	FAD linked oxidase domain protein
sync_2058	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
sync_2061	ENOG4108VPT	UPF0234 protein
sync_2075	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_2087	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
sync_2088	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
sync_2089	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
sync_2090	ENOG4105DZP	Membrane-associated zinc metalloprotease
sync_2091	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
sync_2093	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
sync_2095	ENOG4107RIX	inner membrane protein translocase component YidC
sync_2097	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
sync_2100	ENOG4105KHN	chorismate mutase
sync_2103	ENOG4107T8Q	Glycosyl transferase (Group 1
sync_2107	ENOG4105N6Y	Thioredoxin
sync_2108	ENOG4105CHM	Aminotransferase
sync_2109	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
sync_2110	ENOG4105DR5	peptidase
sync_2111	ENOG4105ETX	regulatoR
sync_2112	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
sync_2113	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
sync_2114	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
sync_2118	ENOG4108K7V	UPF0284 protein
sync_2129	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
sync_2133	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
sync_2135	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
sync_2138	ENOG4107SVH	Potassium channel protein
sync_2140	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
sync_2143	ENOG4105C9X	ppx gppa phosphatase
sync_2146	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
sync_2147	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
sync_2148	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
sync_2149	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
sync_2152	ENOG4105F23	Fibronectin-binding protein
sync_2153	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
sync_2154	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
sync_2156	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
sync_2157	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_2158	ENOG4105CZX	twitching motility protein
sync_2159	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
sync_2163	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
sync_2168	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
sync_2191	ENOG4105K70	DNA-binding protein
sync_2199	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
sync_2200	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
sync_2201	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
sync_2203	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
sync_2205	ENOG4105WH1	Two component transcriptional regulator luxr family
sync_2208	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
sync_2210	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
sync_2213	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
sync_2214	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
sync_2216	ENOG4107QPR	SAICAR synthetase
sync_2218	ENOG4105C12	Phosphoribosylglycinamide synthetase
sync_2220	ENOG4105EHU	Circadian clock protein KaiC
sync_2221	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
sync_2222	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
sync_2223	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
sync_2224	ENOG4105K46	50S ribosomal protein l27
sync_2232	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
sync_2233	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
sync_2234	ENOG4105CDY	transcriptional regulatory protein
sync_2246	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
sync_2248	ENOG4105JFG	SpoIID LytB domain protein
sync_2249	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
sync_2250	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
sync_2255	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
sync_2260	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
sync_2269	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
sync_2271	ENOG4105CFG	Acts as a chaperone (By similarity)
sync_2275	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
sync_2276	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
sync_2279	ENOG4105BZU	Histidine kinase
sync_2280	ENOG4105BZU	Histidine kinase
sync_2281	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
sync_2282	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
sync_2283	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
sync_2284	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
sync_2285	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
sync_2286	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
sync_2287	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
sync_2289	ENOG4105EWV	Sodium calcium exchanger membrane region
sync_2290	ENOG4107RAQ	aminopeptidase
sync_2292	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
sync_2295	ENOG4105DCF	alanine dehydrogenase
sync_2299	ENOG41076WT	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II (By similarity)
sync_2306	ENOG41065W4	chlorophyll a b binding light harvesting protein
sync_2307	ENOG4105K5B	UPF0225 protein
sync_2312	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
sync_2313	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
sync_2314	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
sync_2315	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
sync_2316	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
sync_2317	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
sync_2318	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
sync_2320	ENOG4107SWE	Methyltransferase
sync_2321	ENOG4105EEK	Polypeptide
sync_2328	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
sync_2329	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
sync_2336	ENOG4105C9Q	fumarate hydratase class II
sync_2337	ENOG4105CQR	helicase
sync_2338	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
sync_2340	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
sync_2341	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
sync_2343	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
sync_2345	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
sync_2346	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
sync_2348	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
sync_2354	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
sync_2356	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
sync_2357	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
sync_2358	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
sync_2361	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
sync_2362	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
sync_2363	ENOG4105E66	phosphoriboisomerase A
sync_2364	ENOG4105C0H	protease
sync_2366	ENOG4105BZU	Histidine kinase
sync_2370	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
sync_2371	ENOG4105CHV	Transcription elongation factor NusA
sync_2373	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
sync_2377	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
sync_2379	ENOG4106DI1	Metallothionein family 14
sync_2384	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
sync_2389	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
sync_2390	ENOG4105CHF	Glutathione S-transferase
sync_2392	ENOG4105C5H	ABC transporter
sync_2394	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
sync_2395	ENOG4108IJ9	(ABC) transporter
sync_2398	ENOG4105D52	delta-aminolevulinic acid dehydratase
sync_2401	ENOG4105CHH	sulfate transporter
sync_2424	ENOG4105JZI	cytochrome P450
sync_2456	ENOG4105E0X	reductase
sync_2459	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
sync_2461	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
sync_2467	ENOG4107YU2	histidine triad (hIT) protein
sync_2468	ENOG4105C0P	Mg chelatase subunit ChlI
sync_2470	ENOG410848W	30S ribosomal protein S21
sync_2473	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
sync_2475	ENOG4107W7X	Aldolase
sync_2476	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
sync_2479	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
sync_2487	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
sync_2488	ENOG4106BTU	phycobilisome rod-core linker polypeptide
sync_2491	ENOG4107RZC	phospholipase d
sync_2500	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
sync_2503	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
sync_2508	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
sync_2509	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
sync_2510	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
sync_2512	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
sync_2514	ENOG4105CZN	Potassium uptake protein
sync_2515	ENOG4107ZYR	domain protein
sync_2516	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
sync_2522	ENOG4105C5H	ABC transporter
sync_2523	ENOG4105C0H	protease
sync_2527	ENOG4105CQ7	ATP-dependent helicase
sync_2530	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
sync_2540	ENOG4105ECY	inositol monophosphatase
sync_2543	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
sync_2545	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
sync_2546	ENOG4108IYU	L-aspartate oxidase
sync_2547	ENOG4105CVB	Vitamin K epoxide reductase
sync_2548	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
sync_2552	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
sync_2562	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
sync_2564	ENOG4107TVC	Glycosyl transferase, family 2
sync_2565	ENOG4108DIF	synthase (EC 4.2.1.75)
sync_2568	ENOG4105CVN	desaturase
sync_2575	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
sync_2576	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
sync_2579	ENOG4108PWY	Carbohydrate-selective porin OprB
sync_2581	ENOG4108PWY	Carbohydrate-selective porin OprB
sync_2586	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
sync_2587	ENOG4105VUV	UPF0367 protein
sync_2588	ENOG4108JJB	ABC transporter
sync_2591	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
sync_2592	ENOG4107QRG	dna polymerase iii
sync_2593	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
sync_2594	ENOG4105C59	p-type ATPase
sync_2595	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
sync_2598	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
sync_2599	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
sync_2601	ENOG4105CEY	Amp-dependent synthetase and ligase
sync_2603	ENOG41072GX	Peptidase M22 Glycoprotease
sync_2605	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
sync_2607	ENOG4105FE1	phytoene synthase
sync_2608	ENOG4105CVN	desaturase
sync_2609	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
sync_2611	ENOG4105DUM	transcriptional regulator, lysR family
sync_2614	ENOG4105C8S	subunit m
sync_2621	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
sync_2622	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
sync_2624	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
sync_2625	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
sync_2630	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
sync_2633	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
sync_2636	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
sync_2639	ENOG4105CE4	GlcNAc 6-P deacetylase
sync_2642	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
sync_2647	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
sync_2648	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
sync_2650	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
sync_2653	ENOG4105CEY	Amp-dependent synthetase and ligase
sync_2656	ENOG4105E4F	Isochorismate synthase
sync_2657	ENOG4105D7Z	glutathione synthase
sync_2661	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
sync_2663	ENOG4105DDQ	anthranilate synthase
sync_2665	ENOG4105HDK	L-asparaginase
sync_2666	ENOG4105CIH	Imidazole acetol-phosphate transaminase
sync_2667	ENOG4105C75	arginyL-tRNA synthetase
sync_2669	ENOG4105C0A	alcohol dehydrogenase
sync_2679	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
sync_2685	ENOG4105D64	Mechanosensitive ion channel
sync_2699	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
sync_2701	ENOG4105CNG	UPF0061 protein
sync_2703	ENOG4108JQ6	ABC transporter
sync_2707	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
sync_2709	ENOG4105BZA	Phosphoglycerate kinase
sync_2712	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
sync_2714	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
sync_2715	ENOG4105CIH	Imidazole acetol-phosphate transaminase
sync_2717	ENOG4105GVR	general secretion pathway protein D
sync_2721	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
sync_2722	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
sync_2724	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
sync_2725	ENOG4107Z3D	50S ribosomal protein l10
sync_2726	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
sync_2727	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
sync_2730	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
sync_2732	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
sync_2736	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
sync_2737	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
sync_2739	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
sync_2740	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
sync_2741	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
sync_2742	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
sync_2766	ENOG4105BZS	acriflavin resistance protein
sync_2768	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
sync_2770	ENOG4105C0D	helicase
sync_2773	ENOG4105K3M	)-transporter
sync_2776	ENOG4105CH5	extracellular solute-binding protein, family 7
sync_2778	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
sync_2780	ENOG4105CNW	domain protein
sync_2781	ENOG4105VCQ	rubredoxin
sync_2782	ENOG4105KVH	Transcriptional regulator
sync_2789	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
sync_2790	ENOG4105CXI	aluminum resistance protein
sync_2794	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
sync_2795	ENOG4105CDU	Replicative dna helicase
sync_2795	ENOG4105CDU	Replicative dna helicase
sync_2796	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
sync_2806	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
sync_2812	ENOG4105D8X	mechanosensitive ion channel
sync_2815	ENOG4105CJ1	ABC, transporter
sync_2818	ENOG4105EGS	Mechanosensitive ion channel
sync_2820	ENOG4105BZU	Histidine kinase
sync_2821	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
sync_2822	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
sync_2823	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
sync_2824	ENOG4105D64	Mechanosensitive ion channel
sync_2825	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
sync_2830	ENOG4105PDP	Short chain dehydrogenase
sync_2839	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
sync_2846	ENOG4105DXN	mazG family
sync_2847	ENOG4108YZN	class I peptide chain release factor
sync_2850	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
sync_2851	ENOG4105CYW	agmatinase
sync_2853	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
sync_2854	ENOG4105C9M	aspartyl-trna synthetase
sync_2855	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_2858	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
sync_2859	ENOG4107U96	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
sync_2862	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
sync_2864	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
sync_2865	ENOG4105CRQ	synthase (Component I)
sync_2867	ENOG4107QTZ	amino acid
sync_2868	ENOG4108IV0	ABC, transporter
sync_2869	ENOG4105C0Z	ABC transporter
sync_2871	ENOG4105C32	Amino acid ABC transporter (Permease)
sync_2873	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
sync_2874	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
sync_2875	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
sync_2876	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
sync_2877	ENOG4108YZ9	Urea amidohydrolase subunit gamma
sync_2878	ENOG4105KI2	Urea amidohydrolase subunit beta
sync_2879	ENOG4105CQM	Urea amidohydrolase subunit alpha
sync_2880	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
sync_2885	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
sync_2886	ENOG410838B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
sync_2887	ENOG4107R3J	Transporter
sync_2888	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
sync_2891	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
sync_2892	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
sync_2893	ENOG4108ZAF	Molybdopterin
sync_2895	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
sync_2898	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
sync_2899	ENOG4105TMB	Formate nitrite transporter
sync_2901	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
sync_2904	ENOG4108I0Q	anthranilate phosphoribosyltransferase
sync_2906	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
sync_2907	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
sync_2909	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
sync_2911	ENOG4105CMQ	Chloride channel
sync_2914	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
sync_2919	ENOG4108DN8	FAD dependent oxidoreductase
sync_2920	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
sync_2921	ENOG4105EXC	Acyl-transferase
sync_2923	ENOG4105CFG	Acts as a chaperone (By similarity)
sync_2924	ENOG4105E2X	shikimate dehydrogenase
sync_2926	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
sync_2928	ENOG4105CDH	Citrulline--aspartate ligase
sync_2931	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
sync_2935	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
sync_2936	ENOG4107STW	synthase