locus-tag	class	description
CYB_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CYB_0003	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYB_0005	ENOG4108IXY	short-chain dehydrogenase reductase
CYB_0009	ENOG4105C5H	ABC transporter
CYB_0014	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CYB_0021	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
CYB_0022	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
CYB_0023	ENOG4105CQM	Urea amidohydrolase subunit alpha
CYB_0024	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CYB_0027	ENOG4105VNH	ABC transporter solute-binding protein
CYB_0028	ENOG4105BZU	Histidine kinase
CYB_0038	ENOG4105D7T	ABC transporter
CYB_0040	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CYB_0043	ENOG4105C12	Phosphoribosylglycinamide synthetase
CYB_0045	ENOG4105DCI	Phosphohydrolase
CYB_0048	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CYB_0050	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CYB_0051	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
CYB_0055	ENOG4105KC4	UPF0296 protein
CYB_0056	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CYB_0057	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CYB_0058	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CYB_0064	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CYB_0066	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CYB_0068	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CYB_0071	ENOG4105CHM	Aminotransferase
CYB_0073	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CYB_0078	ENOG4108R99	pseudouridine synthase
CYB_0079	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CYB_0082	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CYB_0084	ENOG4105CRE	cytochrome C
CYB_0088	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CYB_0090	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CYB_0095	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CYB_0096	ENOG4105E4C	Lytic transglycosylase catalytic
CYB_0097	ENOG410902C	phosphohistidine phosphatase, SixA
CYB_0100	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYB_0103	ENOG4105VGQ	Photosystem I subunit X
CYB_0104	ENOG4107JEG	This protein is a component of the reaction center of photosystem II (By similarity)
CYB_0107	ENOG4105EET	magnesium chelatase
CYB_0112	ENOG4107XM9	(LipO)protein
CYB_0113	ENOG4105D3R	alkyl hydroperoxide reductase
CYB_0117	ENOG41080E3	single-stranded DNA-binding protein
CYB_0121	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CYB_0124	ENOG4108WHG	pyridoxamine 5'-phosphate
CYB_0131	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CYB_0132	ENOG4106SMU	thiamine transporter membrane protein
CYB_0136	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
CYB_0137	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYB_0142	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CYB_0144	ENOG4105DSE	periplasmic solute binding protein
CYB_0145	ENOG4105FDK	ABC transporter
CYB_0147	ENOG4105CC5	ABC transporter
CYB_0148	ENOG41068G9	50S ribosomal protein L32
CYB_0151	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CYB_0154	ENOG41086BQ	Protein CrcB homolog
CYB_0157	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CYB_0159	ENOG4105D5T	phosphonate abc transporter
CYB_0166	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
CYB_0167	ENOG4105HRV	phosphonate c-p lyase system protein phnl
CYB_0168	ENOG4105FD8	phosphonate metabolism protein PhnM
CYB_0169	ENOG4107BJW	polysaccharide deacetylase
CYB_0174	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_0177	ENOG41082AN	stage II sporulation protein
CYB_0180	ENOG4107QHM	Sulfite reductase
CYB_0182	ENOG4105C8M	UPF0272 protein
CYB_0184	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CYB_0187	ENOG4105CZX	twitching motility protein
CYB_0188	ENOG4105EUJ	GTP cyclohydrolase i
CYB_0190	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CYB_0192	ENOG4105K63	Thioredoxin
CYB_0194	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CYB_0200	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CYB_0206	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CYB_0208	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_0215	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CYB_0216	ENOG4108NSV	This is one of the two reaction center proteins of photosystem II
CYB_0217	ENOG4105CFH	Aspartokinase
CYB_0227	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CYB_0229	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CYB_0230	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CYB_0231	ENOG4105CGK	Exodeoxyribonuclease III
CYB_0234	ENOG4105D81	ABC transporter, permease
CYB_0235	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CYB_0237	ENOG4107Z6A	sulfate abc transporter permease
CYB_0238	ENOG4108IJ6	ABC transporter
CYB_0239	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CYB_0240	ENOG4105CD5	CoA-binding domain protein
CYB_0241	ENOG4108EKI	Dehydrogenase
CYB_0243	ENOG4105F1A	Pyruvate formate-lyase
CYB_0245	ENOG4105C6N	Formate acetyltransferase
CYB_0247	ENOG4105D7V	transposase
CYB_0249	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CYB_0250	ENOG4105CIK	Amidinotransferase
CYB_0260	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CYB_0261	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CYB_0270	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CYB_0274	ENOG4105CGH	5'-nucleotidase
CYB_0278	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CYB_0280	ENOG4105KXW	Ferredoxin
CYB_0281	ENOG4105YVZ	photosystem II
CYB_0283	ENOG4108UXN	response regulator
CYB_0284	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CYB_0287	ENOG4108N5B	2-phosphosulfolactate phosphatase
CYB_0292	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CYB_0298	ENOG4105C8S	subunit m
CYB_0299	ENOG4108JYK	Dehydrogenase
CYB_0301	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CYB_0304	ENOG4105CTK	cobaltochelatase, cobn subunit
CYB_0308	ENOG4108Z86	Glutamine amidotransferase
CYB_0309	ENOG4105UIB	(ABC) transporter
CYB_0310	ENOG4107SH3	glycosyl transferase, family 39
CYB_0315	ENOG4105ERG	peptidase m48, ste24p
CYB_0316	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CYB_0318	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CYB_0321	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CYB_0323	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CYB_0327	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CYB_0332	ENOG4105F04	LysR family Transcriptional regulator
CYB_0333	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CYB_0340	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CYB_0343	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CYB_0345	ENOG41083W3	Multi-copper polyphenol oxidoreductase laccase
CYB_0347	ENOG4105BZU	Histidine kinase
CYB_0348	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CYB_0349	ENOG4105D74	hydrolase
CYB_0350	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CYB_0352	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CYB_0353	ENOG4105D7V	transposase
CYB_0357	ENOG4105D2N	Aldolase
CYB_0359	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CYB_0360	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CYB_0362	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
CYB_0364	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
CYB_0367	ENOG4108YZT	Adenosylcobinamide kinase
CYB_0371	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
CYB_0372	ENOG4105DJZ	UPF0182 protein
CYB_0375	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CYB_0378	ENOG4107YU2	histidine triad (hIT) protein
CYB_0379	ENOG41081F0	Precorrin-8x methylmutase
CYB_0381	ENOG4105CNW	domain protein
CYB_0382	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CYB_0389	ENOG4105UIB	(ABC) transporter
CYB_0390	ENOG4108JQ9	ABC transporter
CYB_0393	ENOG4105DZC	cytosine deaminase
CYB_0394	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
CYB_0397	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CYB_0399	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CYB_0401	ENOG4105X1Q	TOBE domain protein
CYB_0406	ENOG4105R88	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
CYB_0407	ENOG4105X87	nitrogen fixation
CYB_0408	ENOG4108VQE	nitrogen fixation protein
CYB_0409	ENOG4108UR2	Nitrogen fixation protein NifX
CYB_0410	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
CYB_0411	ENOG4105D0B	Nitrogenase protein alpha chain
CYB_0414	ENOG4108NWW	ferritin dps family protein
CYB_0417	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
CYB_0418	ENOG4105WCA	Ferredoxin
CYB_0419	ENOG4105C3J	Cysteine desulfurase
CYB_0421	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
CYB_0423	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
CYB_0424	ENOG4107S73	homocitrate synthase
CYB_0431	ENOG4105EEK	Polypeptide
CYB_0432	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CYB_0433	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
CYB_0434	ENOG41072GX	Peptidase M22 Glycoprotease
CYB_0435	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CYB_0436	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CYB_0437	ENOG4108X4D	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CYB_0438	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CYB_0444	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CYB_0445	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CYB_0448	ENOG41082B1	30S ribosomal protein S16
CYB_0450	ENOG4105VPX	protein, conserved in bacteria
CYB_0455	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CYB_0457	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CYB_0460	ENOG4105DKP	glycosyl transferase, family 9
CYB_0463	ENOG4105D78	K07001 NTE family protein
CYB_0464	ENOG4105CVJ	phosphoglycerate mutase
CYB_0465	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CYB_0478	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CYB_0481	ENOG4105C37	(CBS) domain
CYB_0482	ENOG4105CXN	decarboxylase
CYB_0484	ENOG4105E4G	Type IV pilus
CYB_0491	ENOG4105DU0	nucleoside hydrolase
CYB_0492	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CYB_0493	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CYB_0494	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CYB_0497	ENOG4105CPF	Cell wall formation (By similarity)
CYB_0500	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CYB_0505	ENOG4108HM4	ABC transporter
CYB_0506	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYB_0507	ENOG4105BZU	Histidine kinase
CYB_0511	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CYB_0516	ENOG4105C26	Dehydrogenase
CYB_0518	ENOG4105D7V	transposase
CYB_0519	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CYB_0522	ENOG4105D9P	serine threonine protein kinase
CYB_0523	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYB_0524	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CYB_0526	ENOG4108IJ0	Aspartate ammonia-lyase
CYB_0533	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
CYB_0538	ENOG4105DR5	peptidase
CYB_0540	ENOG4105C5W	Aldolase
CYB_0541	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CYB_0545	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
CYB_0546	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CYB_0547	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CYB_0549	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
CYB_0553	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CYB_0556	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
CYB_0560	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CYB_0561	ENOG4105C6X	Major Facilitator
CYB_0562	ENOG4105JFG	SpoIID LytB domain protein
CYB_0565	ENOG4108IPT	Naphthoate synthase
CYB_0566	ENOG4108DIF	synthase (EC 4.2.1.75)
CYB_0571	ENOG4108ZIT	Ferredoxin, 2FE-2S
CYB_0579	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CYB_0580	ENOG4108IJ8	ABC transporter
CYB_0584	ENOG41073R8	VanW family
CYB_0590	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
CYB_0597	ENOG4108Z61	cytochrome c-550
CYB_0599	ENOG4108RBV	CRISPR-associated protein, Csx3 family
CYB_0601	ENOG4105D7T	ABC transporter
CYB_0610	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CYB_0612	ENOG4106QSA	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYB_0619	ENOG4108Z61	cytochrome c-550
CYB_0625	ENOG4107QIV	Cytochrome c biogenesis protein
CYB_0626	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
CYB_0631	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYB_0633	ENOG4105JFG	SpoIID LytB domain protein
CYB_0635	ENOG4108Z6B	deaminase
CYB_0642	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CYB_0643	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CYB_0644	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
CYB_0646	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CYB_0647	ENOG4107RFW	hydrolase family 57
CYB_0648	ENOG4105C7K	acetolactate synthase
CYB_0649	ENOG4105FF9	glycosyl transferase, family 39
CYB_0650	ENOG4105D9R	oxidoreductase
CYB_0651	ENOG4108KS2	transglutaminase domain protein
CYB_0653	ENOG4105CQC	Prephenate dehydratase
CYB_0656	ENOG4105D07	Signal peptide peptidase, SppA
CYB_0660	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CYB_0662	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYB_0671	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CYB_0674	ENOG4108QDE	fad dependent oxidoreductase
CYB_0677	ENOG4105CG3	alpha amylase, catalytic region
CYB_0679	ENOG4108RAV	Conserved protein
CYB_0681	ENOG4105CK7	Sodium proline symporter
CYB_0683	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CYB_0688	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CYB_0694	ENOG4105CUT	histidyl-tRNA synthetase
CYB_0696	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CYB_0698	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
CYB_0701	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CYB_0703	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYB_0707	ENOG4107SVH	Potassium channel protein
CYB_0708	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CYB_0709	ENOG4108Z03	MAF-like protein
CYB_0710	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CYB_0725	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CYB_0726	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CYB_0732	ENOG4105C1V	Peptidase, M16
CYB_0735	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CYB_0738	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CYB_0740	ENOG4107QZ7	Cellulose synthase catalytic subunit
CYB_0741	ENOG4105K46	50S ribosomal protein l27
CYB_0742	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CYB_0746	ENOG4105J0C	
CYB_0747	ENOG4107VAM	peptidase, m28
CYB_0748	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
CYB_0752	ENOG4105CEN	a g-specific adenine glycosylase
CYB_0755	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CYB_0759	ENOG4108ZG0	Ompa motb domain protein
CYB_0766	ENOG4108R6G	acetyltransferase
CYB_0770	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYB_0774	ENOG4105C0Z	ABC transporter
CYB_0775	ENOG4108IV0	ABC, transporter
CYB_0783	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CYB_0784	ENOG4107QRA	Extracellular solute-binding protein, family 5
CYB_0786	ENOG4105CPK	Glycosyl transferase (Group 1
CYB_0796	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CYB_0798	ENOG4107QJE	Chromosome Partitioning Protein
CYB_0801	ENOG4106H3A	restriction
CYB_0803	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CYB_0807	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CYB_0808	ENOG4105EGS	Mechanosensitive ion channel
CYB_0810	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
CYB_0814	ENOG4105D7V	transposase
CYB_0815	ENOG4108ZIT	Ferredoxin, 2FE-2S
CYB_0816	ENOG4105CMG	Carbohydrate kinase
CYB_0821	ENOG4105DBV	ornithine carbamoyltransferase
CYB_0823	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CYB_0825	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CYB_0828	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CYB_0830	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CYB_0832	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CYB_0847	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CYB_0849	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CYB_0852	ENOG4107QRP	cobalamin biosynthesis protein CobW
CYB_0853	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
CYB_0854	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
CYB_0856	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CYB_0857	ENOG4105EMU	Dehydrogenase
CYB_0858	ENOG4105EB3	Histidine kinase
CYB_0864	ENOG41085GJ	domain protein
CYB_0869	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_0870	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CYB_0872	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_0874	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CYB_0877	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CYB_0878	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CYB_0881	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CYB_0884	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CYB_0889	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CYB_0891	ENOG4108VPT	UPF0234 protein
CYB_0895	ENOG4105CJN	penicillin-binding protein
CYB_0896	ENOG4105K70	DNA-binding protein
CYB_0897	ENOG4107QZB	decarboxylase
CYB_0901	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CYB_0905	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CYB_0908	ENOG4105CTK	cobaltochelatase, cobn subunit
CYB_0916	ENOG4105MJ2	Competence protein
CYB_0917	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CYB_0918	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CYB_0919	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CYB_0920	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CYB_0921	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CYB_0922	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CYB_0927	ENOG4105CJP	fad dependent oxidoreductase
CYB_0928	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CYB_0930	ENOG4105DRP	amino acid AbC transporter
CYB_0931	ENOG4105EZ7	amino acid ABC transporter
CYB_0932	ENOG4107QXX	ABC transporter
CYB_0933	ENOG4105CDA	abc transporter atp-binding protein
CYB_0937	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CYB_0939	ENOG4105D6V	phycocyanin beta subunit
CYB_0941	ENOG4106DMB	CpcD phycobilisome linker domain protein
CYB_0942	ENOG41078GB	pbs lyase
CYB_0943	ENOG4108V9J	phycocyanobilin lyase
CYB_0944	ENOG4106BTU	phycobilisome rod-core linker polypeptide
CYB_0947	ENOG4108ZF3	Phosphatase
CYB_0948	ENOG4105DGU	Histone deacetylase
CYB_0958	ENOG4105C0H	protease
CYB_0960	ENOG4105K63	Thioredoxin
CYB_0970	ENOG4105CFP	Peptidase U32
CYB_0974	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CYB_0985	ENOG4108R85	Short chain dehydrogenase
CYB_0986	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CYB_0987	ENOG4105BZU	Histidine kinase
CYB_0989	ENOG41083MR	nifu domain-containing protein
CYB_0990	ENOG4105DZP	Membrane-associated zinc metalloprotease
CYB_0992	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CYB_0994	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CYB_0996	ENOG4105CJN	penicillin-binding protein
CYB_1001	ENOG4108KGH	TRANSCRIPTIONal
CYB_1002	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CYB_1003	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CYB_1005	ENOG4105C5F	glutamine synthetase
CYB_1006	ENOG4105E2X	shikimate dehydrogenase
CYB_1008	ENOG4105ETX	regulatoR
CYB_1012	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CYB_1013	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
CYB_1016	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
CYB_1018	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYB_1020	ENOG4105CVJ	phosphoglycerate mutase
CYB_1022	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CYB_1026	ENOG4105DC7	peptidase M24
CYB_1027	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CYB_1028	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYB_1030	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CYB_1044	ENOG4105ETX	regulatoR
CYB_1049	ENOG4105D7Z	glutathione synthase
CYB_1051	ENOG41083EU	50s ribosomal protein l28
CYB_1057	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYB_1060	ENOG4105CVN	desaturase
CYB_1063	ENOG4107TTD	cytosine deaminase
CYB_1067	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CYB_1070	ENOG4107RIQ	Sulfate adenylate transferase
CYB_1073	ENOG4105DX0	Hemolysin A
CYB_1074	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CYB_1075	ENOG4105E2Z	phosphate ABC transporter (Permease
CYB_1076	ENOG4105C8U	phosphate abc transporter
CYB_1077	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CYB_1080	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CYB_1081	ENOG4105CDU	Replicative dna helicase
CYB_1083	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
CYB_1084	ENOG4107TS3	membrane protein, TerC
CYB_1086	ENOG4105DHJ	ABC, transporter
CYB_1089	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CYB_1094	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CYB_1095	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CYB_1099	ENOG4107QRG	dna polymerase iii
CYB_1100	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
CYB_1106	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CYB_1107	ENOG4105EYH	Exonuclease
CYB_1111	ENOG4105CTK	cobaltochelatase, cobn subunit
CYB_1112	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CYB_1117	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CYB_1119	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CYB_1126	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CYB_1127	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CYB_1130	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CYB_1141	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CYB_1142	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYB_1145	ENOG4107QRI	Phosphoketolase
CYB_1146	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CYB_1160	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CYB_1161	ENOG4105C9M	aspartyl-trna synthetase
CYB_1162	ENOG4105DSE	periplasmic solute binding protein
CYB_1163	ENOG4105DIK	(ABC) transporter
CYB_1164	ENOG4105CC5	ABC transporter
CYB_1166	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CYB_1168	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CYB_1171	ENOG4105CKI	cobalamin synthesis protein
CYB_1184	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CYB_1186	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CYB_1191	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CYB_1193	ENOG4105EWK	phytoene
CYB_1200	ENOG41090MY	MarR family Transcriptional regulator
CYB_1208	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CYB_1209	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CYB_1212	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CYB_1214	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CYB_1217	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CYB_1221	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CYB_1222	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CYB_1223	ENOG4107Z3D	50S ribosomal protein l10
CYB_1224	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CYB_1229	ENOG410848W	30S ribosomal protein S21
CYB_1233	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CYB_1234	ENOG4105BZ1	(ABC) transporter
CYB_1235	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CYB_1236	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CYB_1242	ENOG4105WH1	Two component transcriptional regulator luxr family
CYB_1244	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CYB_1245	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
CYB_1249	ENOG4105BZU	Histidine kinase
CYB_1251	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CYB_1254	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
CYB_1258	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CYB_1261	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
CYB_1262	ENOG4105CHM	Aminotransferase
CYB_1263	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CYB_1264	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CYB_1266	ENOG4108RXX	maleylacetoacetate isomerase
CYB_1267	ENOG4105DVW	rieske (2Fe-2S)
CYB_1268	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CYB_1269	ENOG4105JFG	SpoIID LytB domain protein
CYB_1272	ENOG4106855	Competence protein
CYB_1278	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_1281	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
CYB_1283	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CYB_1289	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYB_1299	ENOG4105F38	ABC transporter, permease
CYB_1301	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CYB_1304	ENOG4105C6E	dna polymerase iii
CYB_1306	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CYB_1316	ENOG4105WAB	arsR family transcriptional regulator
CYB_1320	ENOG4105C7Z	Conserved Protein
CYB_1321	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CYB_1326	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CYB_1327	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CYB_1330	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CYB_1335	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CYB_1336	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CYB_1337	ENOG4107ZYR	domain protein
CYB_1340	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CYB_1344	ENOG4105BZU	Histidine kinase
CYB_1348	ENOG41086B8	CoB-CoM heterodisulfide reductase
CYB_1350	ENOG4105CDY	transcriptional regulatory protein
CYB_1351	ENOG41080XM	UPF0145 protein
CYB_1353	ENOG4108RVA	ribokinase
CYB_1354	ENOG4108VB1	regulatoR
CYB_1360	ENOG4108IY8	ABC, transporter
CYB_1362	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CYB_1363	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CYB_1371	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CYB_1372	ENOG410686T	photosystem II reaction center protein N
CYB_1373	ENOG4105WIA	photosystem II reaction center protein H
CYB_1382	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CYB_1384	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CYB_1390	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CYB_1391	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CYB_1394	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYB_1401	ENOG4107GBW	cellulosome anchoring protein cohesin
CYB_1404	ENOG41084W5	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CYB_1407	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CYB_1410	ENOG4105BZU	Histidine kinase
CYB_1414	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CYB_1417	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
CYB_1419	ENOG4105C8Y	Acetylornithine aminotransferase
CYB_1421	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
CYB_1424	ENOG4105C1Q	protoporphyrinogen oxidase
CYB_1427	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CYB_1430	ENOG4105EYM	Major Facilitator superfamily
CYB_1431	ENOG4105D9R	oxidoreductase
CYB_1434	ENOG4108NWW	ferritin dps family protein
CYB_1436	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CYB_1437	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CYB_1438	ENOG4108MAQ	allophycocyanin alpha
CYB_1439	ENOG4105FBM	allophycocyanin beta subunit
CYB_1440	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
CYB_1441	ENOG4105CJ1	ABC, transporter
CYB_1442	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CYB_1443	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
CYB_1444	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
CYB_1445	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CYB_1447	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYB_1454	ENOG4107U45	Cobalt transport protein
CYB_1458	ENOG4105EMN	RNA polymerase sigma factor
CYB_1463	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
CYB_1464	ENOG4107TYH	extracellular solute-binding protein family 1
CYB_1467	ENOG4105D5T	phosphonate abc transporter
CYB_1471	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_1477	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYB_1478	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CYB_1480	ENOG4108FN7	Aldo keto reductase
CYB_1481	ENOG4105C59	p-type ATPase
CYB_1485	ENOG4108TQ9	Histidine kinase
CYB_1487	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CYB_1489	ENOG4108JQ9	ABC transporter
CYB_1492	ENOG4105C22	threonyL-tRNA synthetase
CYB_1493	ENOG4105C9X	ppx gppa phosphatase
CYB_1495	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
CYB_1496	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
CYB_1498	ENOG4106DN3	This protein is a component of the reaction center of photosystem II (By similarity)
CYB_1499	ENOG4108SIY	photosystem I reaction center protein subunit XI
CYB_1500	ENOG41068FK	Photosystem I reaction center subunit VIII
CYB_1503	ENOG4105CFG	Acts as a chaperone (By similarity)
CYB_1508	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CYB_1510	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CYB_1511	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CYB_1514	ENOG4105CRK	lysyL-tRNA synthetase
CYB_1516	ENOG4105JDN	Copper resistance protein
CYB_1520	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CYB_1521	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CYB_1534	ENOG4105CE9	30S ribosomal protein S2
CYB_1535	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CYB_1536	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CYB_1550	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CYB_1554	ENOG41080HI	glycine oxidase
CYB_1555	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CYB_1559	ENOG4105DFU	Cell wall formation (By similarity)
CYB_1560	ENOG4105D4A	Cell wall formation (By similarity)
CYB_1570	ENOG4105D49	3-dehydroquinate synthase
CYB_1577	ENOG41067V7	50S ribosomal protein L36
CYB_1578	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CYB_1579	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CYB_1580	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYB_1581	ENOG4108ZT0	50S ribosomal protein l17
CYB_1582	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CYB_1583	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CYB_1584	ENOG4108UJD	30S ribosomal protein S9
CYB_1585	ENOG41082HT	Binds the 23S rRNA (By similarity)
CYB_1586	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CYB_1589	ENOG4105VN1	Heat shock protein
CYB_1605	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CYB_1606	ENOG4105MSA	Photosystem II reaction center W protein
CYB_1607	ENOG4105BZW	Glycerate kinase
CYB_1611	ENOG4105CHH	sulfate transporter
CYB_1613	ENOG4108PWY	Carbohydrate-selective porin OprB
CYB_1616	ENOG4107QVP	Dehydrogenase
CYB_1618	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CYB_1619	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CYB_1620	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CYB_1621	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYB_1622	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYB_1626	ENOG4108SGF	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYB_1629	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CYB_1630	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYB_1631	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CYB_1633	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CYB_1634	ENOG41084GG	50S ribosomal protein L33
CYB_1636	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CYB_1638	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CYB_1639	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CYB_1640	ENOG4105BZU	Histidine kinase
CYB_1641	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CYB_1645	ENOG4105C8B	TIGR00159 family
CYB_1646	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CYB_1648	ENOG4107QI6	Cysteine desulfurase
CYB_1649	ENOG4105CNI	cell division protein FtsW
CYB_1651	ENOG4105C2J	ABC transporter
CYB_1653	ENOG4105BZU	Histidine kinase
CYB_1655	ENOG4105K6T	rare lipoprotein A
CYB_1656	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CYB_1657	ENOG4105CJ1	ABC, transporter
CYB_1662	ENOG4105KXI	murein peptide amidase A
CYB_1664	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
CYB_1665	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CYB_1668	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CYB_1670	ENOG4105DHP	deoxycytidine triphosphate deaminase
CYB_1678	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CYB_1680	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CYB_1683	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CYB_1685	ENOG4105D0M	Protease HtpX homolog
CYB_1687	ENOG4105CAS	nag kinase
CYB_1689	ENOG4105BZ1	(ABC) transporter
CYB_1691	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYB_1693	ENOG4105BZA	Phosphoglycerate kinase
CYB_1694	ENOG4105CVN	desaturase
CYB_1695	ENOG4105FE1	phytoene synthase
CYB_1696	ENOG4108I5C	dEAD DEAH box helicase
CYB_1700	ENOG4105CVR	type I restriction-modification system
CYB_1701	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CYB_1704	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CYB_1709	ENOG4108MJ3	acetyltransferase
CYB_1711	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
CYB_1712	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CYB_1713	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
CYB_1727	ENOG4105C0D	helicase
CYB_1734	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CYB_1736	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
CYB_1737	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CYB_1739	ENOG4105C5H	ABC transporter
CYB_1740	ENOG4108UNF	response regulator
CYB_1741	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CYB_1746	ENOG4105DFA	alanine racemase domain protein
CYB_1747	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CYB_1750	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CYB_1751	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CYB_1752	ENOG4105CDH	Citrulline--aspartate ligase
CYB_1757	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CYB_1764	ENOG4108R0D	protein with myosin-like
CYB_1766	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CYB_1772	ENOG4105CNW	domain protein
CYB_1782	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CYB_1783	ENOG4105D3Q	Sugar transferase
CYB_1784	ENOG4107QPR	SAICAR synthetase
CYB_1786	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CYB_1788	ENOG4105CND	Glycosyl transferase, family 2
CYB_1789	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CYB_1790	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CYB_1793	ENOG4105MN7	Carbon dioxide concentrating mechanism protein
CYB_1794	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
CYB_1796	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
CYB_1797	ENOG4105KNY	Microcompartments protein
CYB_1800	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
CYB_1803	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
CYB_1806	ENOG4107SVH	Potassium channel protein
CYB_1811	ENOG4105C8S	subunit m
CYB_1812	ENOG4105D65	subunit l
CYB_1816	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYB_1817	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYB_1818	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CYB_1820	ENOG4105DR5	peptidase
CYB_1821	ENOG4105C8N	cysteinyl-tRNA synthetase
CYB_1824	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CYB_1827	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CYB_1833	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
CYB_1839	ENOG4105KHN	chorismate mutase
CYB_1842	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CYB_1861	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CYB_1863	ENOG4105K64	Glycosyl transferase, family 2
CYB_1867	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CYB_1868	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CYB_1874	ENOG4107791	aminotransferase class V
CYB_1875	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CYB_1877	ENOG4107QJE	Chromosome Partitioning Protein
CYB_1880	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CYB_1882	ENOG4105CDA	abc transporter atp-binding protein
CYB_1883	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CYB_1886	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CYB_1887	ENOG4105CAK	Cell division ATP-binding protein ftsE
CYB_1895	ENOG4105BZU	Histidine kinase
CYB_1897	ENOG4105DR5	peptidase
CYB_1898	ENOG4108JJB	ABC transporter
CYB_1900	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CYB_1902	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CYB_1903	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CYB_1904	ENOG4105CHR	reductase
CYB_1909	ENOG4108PJD	permease
CYB_1912	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CYB_1913	ENOG4105E2Z	phosphate ABC transporter (Permease
CYB_1914	ENOG4105C8U	phosphate abc transporter
CYB_1915	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CYB_1917	ENOG4105CXT	aspartate transcarbamylase
CYB_1921	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CYB_1927	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CYB_1928	ENOG4107YCR	Transcriptional regulator, ARSR family
CYB_1930	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CYB_1931	ENOG4105PGM	cation diffusion facilitator family transporter
CYB_1933	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CYB_1934	ENOG4105CBS	Chea signal transduction histidine kinase
CYB_1934	ENOG4105CBS	Chea signal transduction histidine kinase
CYB_1938	ENOG4105M3Z	response regulator
CYB_1939	ENOG4108UNF	response regulator
CYB_1941	ENOG4105C10	Electron transfer flavoprotein
CYB_1942	ENOG4105BZJ	Electron transfer flavoprotein
CYB_1944	ENOG4105C75	arginyL-tRNA synthetase
CYB_1948	ENOG4105DUM	transcriptional regulator, lysR family
CYB_1949	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CYB_1950	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CYB_1959	ENOG4105K8N	protein family UPF0079, ATPase
CYB_1960	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CYB_1961	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CYB_1964	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CYB_1972	ENOG4105FFC	UPF0187 protein
CYB_1975	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CYB_1977	ENOG4107QN2	dihydrolipoyl dehydrogenase
CYB_1978	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CYB_1980	ENOG4105DKP	glycosyl transferase, family 9
CYB_1983	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CYB_1986	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CYB_1987	ENOG4105C01	Dihydroxy-acid dehydratase
CYB_1990	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CYB_1991	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CYB_1993	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CYB_1994	ENOG4105W5Q	DNA repair protein (RadC
CYB_1995	ENOG4107SH3	glycosyl transferase, family 39
CYB_1999	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYB_2004	ENOG4105C8S	subunit m
CYB_2005	ENOG4105D44	asparaginase
CYB_2008	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CYB_2011	ENOG4108IV0	ABC, transporter
CYB_2012	ENOG4105C0Z	ABC transporter
CYB_2014	ENOG4105C32	Amino acid ABC transporter (Permease)
CYB_2015	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CYB_2018	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CYB_2021	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CYB_2023	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CYB_2030	ENOG4105CJ1	ABC, transporter
CYB_2031	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_2037	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CYB_2038	ENOG4105E66	phosphoriboisomerase A
CYB_2044	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CYB_2045	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CYB_2055	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CYB_2060	ENOG4108UNF	response regulator
CYB_2061	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYB_2064	ENOG4107Y80	Major Facilitator superfamily
CYB_2065	ENOG4108KMV	Glycosyl transferase (Group 1
CYB_2066	ENOG4107SGM	protein serine threonine phosphatase
CYB_2070	ENOG4105CH7	arginosuccinase
CYB_2078	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
CYB_2079	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CYB_2082	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CYB_2084	ENOG4105C32	Amino acid ABC transporter (Permease)
CYB_2088	ENOG4105CBG	Sulfatase
CYB_2091	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CYB_2092	ENOG4107VXZ	Hydrolase
CYB_2099	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
CYB_2100	ENOG4105C4R	Atp-dependent dna helicase
CYB_2101	ENOG410667J	hydrolase
CYB_2109	ENOG4105CPF	Cell wall formation (By similarity)
CYB_2110	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CYB_2112	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CYB_2114	ENOG4105CJW	magnesium transporter
CYB_2119	ENOG41083KH	UPF0102 protein
CYB_2120	ENOG4105M0M	Tetracycline resistance protein
CYB_2124	ENOG4105E89	ABC transporter
CYB_2125	ENOG4105DRP	amino acid AbC transporter
CYB_2127	ENOG4108J01	L-aspartate oxidase
CYB_2131	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CYB_2132	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CYB_2140	ENOG4107S52	alpha-2-macroglobulin domain protein
CYB_2142	ENOG4105CZX	twitching motility protein
CYB_2143	ENOG4107QHF	type ii secretion system protein e
CYB_2144	ENOG4105C7K	acetolactate synthase
CYB_2145	ENOG4105DTQ	mandelate racemase muconate lactonizing
CYB_2151	ENOG4105CSM	endonuclease III
CYB_2152	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CYB_2153	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
CYB_2154	ENOG410828V	rubredoxin
CYB_2157	ENOG4105CP7	Triose-phosphate isomerase
CYB_2160	ENOG4105D0M	Protease HtpX homolog
CYB_2161	ENOG4105BZ1	(ABC) transporter
CYB_2163	ENOG4105BZU	Histidine kinase
CYB_2165	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CYB_2166	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CYB_2169	ENOG4107R0W	ABC transporter
CYB_2173	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CYB_2174	ENOG4105D7V	transposase
CYB_2175	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CYB_2181	ENOG4108IQE	Amp-dependent synthetase and ligase
CYB_2184	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CYB_2186	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYB_2189	ENOG4105DVK	Precorrin-2 c20-methyltransferase
CYB_2190	ENOG4105WN5	stage II sporulation protein
CYB_2193	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
CYB_2195	ENOG4105VF7	tolerance protein
CYB_2196	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CYB_2200	ENOG4105F8J	Adenylate Guanylate cyclase
CYB_2203	ENOG4108ZAF	Molybdopterin
CYB_2206	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYB_2209	ENOG4105D38	putrescine abc transporter
CYB_2212	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CYB_2216	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
CYB_2217	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CYB_2222	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CYB_2229	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CYB_2241	ENOG4107RIX	inner membrane protein translocase component YidC
CYB_2245	ENOG4105CHV	Transcription elongation factor NusA
CYB_2246	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
CYB_2251	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYB_2252	ENOG4105CYW	agmatinase
CYB_2257	ENOG4105CBT	Fructose-1,6-bisphosphatase
CYB_2258	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CYB_2262	ENOG4105CEV	competence damage-inducible protein
CYB_2263	ENOG4105D7V	transposase
CYB_2265	ENOG4108JH3	
CYB_2268	ENOG41065W4	chlorophyll a b binding light harvesting protein
CYB_2270	ENOG4107E2E	PKHD-type hydroxylase
CYB_2274	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CYB_2276	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CYB_2277	ENOG4105BZU	Histidine kinase
CYB_2278	ENOG4105CVB	Vitamin K epoxide reductase
CYB_2280	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CYB_2284	ENOG4105D0M	Protease HtpX homolog
CYB_2292	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CYB_2293	ENOG4105HHA	aminodeoxychorismate lyase
CYB_2294	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
CYB_2296	ENOG4105DUM	transcriptional regulator, lysR family
CYB_2297	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
CYB_2299	ENOG4105E4F	Isochorismate synthase
CYB_2304	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CYB_2306	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CYB_2308	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CYB_2309	ENOG4105D8X	mechanosensitive ion channel
CYB_2315	ENOG4105C6T	cysteine synthase
CYB_2316	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
CYB_2318	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CYB_2319	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CYB_2328	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CYB_2329	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CYB_2332	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CYB_2333	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_2334	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CYB_2338	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CYB_2340	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CYB_2341	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CYB_2346	ENOG4105C59	p-type ATPase
CYB_2350	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CYB_2352	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CYB_2353	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CYB_2356	ENOG4105CKI	cobalamin synthesis protein
CYB_2358	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CYB_2362	ENOG41086DT	Membrane protein of unknown function
CYB_2365	ENOG4105D6J	arsenicaL-resistance protein
CYB_2366	ENOG4108UXE	Protein tyrosine phosphatase
CYB_2368	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CYB_2369	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CYB_2370	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CYB_2374	ENOG4108Z4U	Ferredoxin
CYB_2378	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CYB_2383	ENOG4108IUZ	ABC transporter
CYB_2389	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CYB_2391	ENOG4107XKF	NMT1 THI5 Like Domain Protein
CYB_2394	ENOG4105WHD	thiamine biosynthesis protein ThiS
CYB_2395	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CYB_2399	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYB_2400	ENOG4105DA5	(ABC) transporter
CYB_2402	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CYB_2404	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CYB_2411	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CYB_2417	ENOG4105DDQ	anthranilate synthase
CYB_2425	ENOG4105CAT	Cytidine monophosphate kinase
CYB_2426	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
CYB_2427	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYB_2432	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CYB_2433	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CYB_2436	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYB_2437	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYB_2438	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYB_2439	ENOG4105DWF	phosphomethylpyrimidine kinase
CYB_2441	ENOG4105E6N	shikimate quinate 5-dehydrogenase
CYB_2442	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
CYB_2449	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CYB_2451	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CYB_2456	ENOG4105D52	delta-aminolevulinic acid dehydratase
CYB_2458	ENOG4107KHP	This protein is a component of the reaction center of photosystem II (By similarity)
CYB_2461	ENOG4107USA	Thioredoxin
CYB_2462	ENOG4107TK4	histidinol-phosphate phosphatase
CYB_2471	ENOG4105BZU	Histidine kinase
CYB_2478	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CYB_2480	ENOG4108IYU	L-aspartate oxidase
CYB_2481	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CYB_2482	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CYB_2483	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CYB_2489	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYB_2492	ENOG4105DFF	Rod shape-determining protein mreb
CYB_2493	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CYB_2496	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYB_2501	ENOG4105ETX	regulatoR
CYB_2502	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CYB_2511	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CYB_2512	ENOG4108JQC	penicillin-binding protein 1A
CYB_2517	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CYB_2524	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CYB_2531	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CYB_2533	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
CYB_2537	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
CYB_2539	ENOG4108Z61	cytochrome c-550
CYB_2540	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CYB_2542	ENOG4105CXI	aluminum resistance protein
CYB_2545	ENOG41080Y1	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CYB_2548	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CYB_2550	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CYB_2553	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_2555	ENOG41080UQ	Transcriptional regulator
CYB_2558	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CYB_2559	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
CYB_2561	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_2567	ENOG4108K7V	UPF0284 protein
CYB_2568	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CYB_2570	ENOG4105I3K	Ferric uptake regulator, Fur family
CYB_2572	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYB_2574	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CYB_2575	ENOG4105D9P	serine threonine protein kinase
CYB_2577	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
CYB_2579	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
CYB_2581	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CYB_2586	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CYB_2588	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CYB_2590	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CYB_2593	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
CYB_2597	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CYB_2598	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CYB_2599	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CYB_2600	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CYB_2601	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CYB_2602	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CYB_2603	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CYB_2604	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CYB_2605	ENOG410848H	50s ribosomal protein l29
CYB_2606	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CYB_2607	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CYB_2608	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CYB_2609	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CYB_2610	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CYB_2611	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CYB_2612	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CYB_2613	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CYB_2614	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CYB_2615	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CYB_2616	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CYB_2618	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CYB_2622	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYB_2625	ENOG4105CD2	stage iii sporulation protein aa
CYB_2627	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
CYB_2628	ENOG4105E0X	reductase
CYB_2629	ENOG4107SJW	iron permease, FTR1
CYB_2631	ENOG4108JJB	ABC transporter
CYB_2632	ENOG4105VUV	UPF0367 protein
CYB_2635	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CYB_2640	ENOG4105D7V	transposase
CYB_2643	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CYB_2647	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CYB_2665	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CYB_2666	ENOG41084GC	stage II sporulation protein
CYB_2667	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYB_2671	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CYB_2672	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CYB_2673	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CYB_2674	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYB_2675	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYB_2676	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYB_2677	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYB_2679	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
CYB_2680	ENOG4105PA3	atp synthase
CYB_2684	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CYB_2686	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CYB_2687	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CYB_2689	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_2695	ENOG4105CQB	FAD linked oxidase domain protein
CYB_2696	ENOG4105D7V	transposase
CYB_2704	ENOG4108YZA	Nitrogen regulatory protein pii
CYB_2706	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CYB_2708	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CYB_2714	ENOG4105D7V	transposase
CYB_2718	ENOG4105C0P	Mg chelatase subunit ChlI
CYB_2719	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CYB_2722	ENOG4105BZU	Histidine kinase
CYB_2723	ENOG4105ETX	regulatoR
CYB_2728	ENOG4105E0A	ABC, transporter
CYB_2729	ENOG4105EHG	Permease protein
CYB_2731	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CYB_2734	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYB_2736	ENOG41078GB	pbs lyase
CYB_2741	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYB_2745	ENOG4105X25	
CYB_2747	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CYB_2749	ENOG4105M3Z	response regulator
CYB_2752	ENOG4105CBS	Chea signal transduction histidine kinase
CYB_2752	ENOG4105CBS	Chea signal transduction histidine kinase
CYB_2755	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CYB_2756	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CYB_2759	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CYB_2760	ENOG4105XCI	PucC protein
CYB_2767	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CYB_2774	ENOG4105VFU	Rna-binding protein
CYB_2775	ENOG4107RH8	nuclease SbcCD subunit D
CYB_2779	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CYB_2781	ENOG4105CFG	Acts as a chaperone (By similarity)
CYB_2783	ENOG4106FVC	RNA methyltransferase
CYB_2785	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYB_2786	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CYB_2787	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYB_2788	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
CYB_2789	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYB_2791	ENOG4105BZU	Histidine kinase
CYB_2798	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
CYB_2799	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CYB_2804	ENOG4105C5F	glutamine synthetase
CYB_2806	ENOG4105C3M	thioredoxin reductase
CYB_2807	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CYB_2810	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CYB_2811	ENOG4105ESV	Glycosyl transferase, family 4
CYB_2813	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CYB_2817	ENOG4108VX5	3-methyladenine DNA glycosylase
CYB_2822	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CYB_2823	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CYB_2828	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CYB_2833	ENOG4105DWF	phosphomethylpyrimidine kinase
CYB_2837	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CYB_2841	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYB_2844	ENOG4107RSS	Hydrogenase accessory protein HypB
CYB_2845	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYB_2846	ENOG4105CQB	FAD linked oxidase domain protein
CYB_2847	ENOG4107SWE	Methyltransferase
CYB_2848	ENOG41084A0	50s ribosomal protein L35
CYB_2849	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CYB_2850	ENOG4106PMH	Extracellular solute-binding protein family 3
CYB_2856	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_2857	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYB_2860	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CYB_2863	ENOG4108Z0R	Transferase
CYB_2874	ENOG4105ECP	epimerase
CYB_2875	ENOG4105D65	subunit l
CYB_2876	ENOG4105C8S	subunit m
CYB_2881	ENOG4105C8T	Leucyl-tRNA synthetase
CYB_2885	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CYB_2889	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CYB_2892	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CYB_2893	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
CYB_2894	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CYB_2895	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CYB_2897	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CYB_2898	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CYB_2901	ENOG4105DXN	mazG family
CYB_2904	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CYB_2905	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CYB_2912	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CYB_2913	ENOG4105DWV	Homoserine O-trans-acetylase
CYB_2916	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CYB_2918	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
CYB_2919	ENOG4105C89	phosphohexose isomerase
CYB_2924	ENOG4105C3G	gtp-binding protein
CYB_2925	ENOG4105D7V	transposase
CYB_2926	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYB_2928	ENOG4105CPC	Aldo Keto reductase
CYB_2929	ENOG4108SHJ	s-layer protein
CYB_2931	ENOG4106MP8	UPF0754 membrane protein
CYB_2932	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CYB_2933	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYB_2934	ENOG4105CFG	Acts as a chaperone (By similarity)
CYB_2935	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYB_2937	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CYB_2940	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CYB_2941	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)