locus-tag	class	description
CYA_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CYA_0005	ENOG4108IXY	short-chain dehydrogenase reductase
CYA_0009	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CYA_0011	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CYA_0017	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CYA_0021	ENOG4105KRF	dihydroneopterin aldolase
CYA_0024	ENOG4105C3G	gtp-binding protein
CYA_0025	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CYA_0035	ENOG4108SIY	photosystem I reaction center protein subunit XI
CYA_0036	ENOG41068FK	Photosystem I reaction center subunit VIII
CYA_0041	ENOG4105XCI	PucC protein
CYA_0046	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CYA_0051	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CYA_0055	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CYA_0075	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CYA_0081	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CYA_0082	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CYA_0087	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CYA_0093	ENOG4108UNF	response regulator
CYA_0094	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYA_0099	ENOG4105CPK	Glycosyl transferase (Group 1
CYA_0100	ENOG4107SGM	protein serine threonine phosphatase
CYA_0103	ENOG4105CH7	arginosuccinase
CYA_0107	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CYA_0109	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CYA_0110	ENOG4105CPF	Cell wall formation (By similarity)
CYA_0118	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CYA_0125	ENOG4105VFU	Rna-binding protein
CYA_0126	ENOG4107RH8	nuclease SbcCD subunit D
CYA_0128	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CYA_0130	ENOG4105CFG	Acts as a chaperone (By similarity)
CYA_0131	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CYA_0133	ENOG4108IQE	Amp-dependent synthetase and ligase
CYA_0142	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYA_0143	ENOG4105C7B	Threonine dehydratase
CYA_0147	ENOG4105CAK	Cell division ATP-binding protein ftsE
CYA_0148	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CYA_0151	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CYA_0152	ENOG4105CDA	abc transporter atp-binding protein
CYA_0154	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CYA_0155	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CYA_0158	ENOG4105D7V	transposase
CYA_0167	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CYA_0178	ENOG4105CD3	dihydroorotase
CYA_0180	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CYA_0188	ENOG410848W	30S ribosomal protein S21
CYA_0189	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CYA_0193	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CYA_0194	ENOG4105BZ1	(ABC) transporter
CYA_0195	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CYA_0196	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CYA_0201	ENOG4105WH1	Two component transcriptional regulator luxr family
CYA_0203	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CYA_0204	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
CYA_0207	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CYA_0211	ENOG4105DGU	Histone deacetylase
CYA_0212	ENOG4108ZF3	Phosphatase
CYA_0215	ENOG4106BTU	phycobilisome rod-core linker polypeptide
CYA_0216	ENOG4108V9J	phycocyanobilin lyase
CYA_0217	ENOG41078GB	pbs lyase
CYA_0218	ENOG4106DMB	CpcD phycobilisome linker domain protein
CYA_0221	ENOG4105D6V	phycocyanin beta subunit
CYA_0223	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CYA_0224	ENOG4105CP9	extracellular ligand-binding receptor
CYA_0226	ENOG4105D7V	transposase
CYA_0228	ENOG4105CDA	abc transporter atp-binding protein
CYA_0238	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CYA_0239	ENOG4105D3Q	Sugar transferase
CYA_0240	ENOG4107QPR	SAICAR synthetase
CYA_0243	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CYA_0245	ENOG4105CND	Glycosyl transferase, family 2
CYA_0246	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CYA_0247	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CYA_0249	ENOG4105D0M	Protease HtpX homolog
CYA_0252	ENOG4107QIV	Cytochrome c biogenesis protein
CYA_0254	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
CYA_0255	ENOG4105CQB	FAD linked oxidase domain protein
CYA_0258	ENOG4108QDE	fad dependent oxidoreductase
CYA_0263	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CYA_0267	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CYA_0268	ENOG4107QRA	Extracellular solute-binding protein, family 5
CYA_0270	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYA_0277	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CYA_0278	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CYA_0282	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CYA_0283	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYA_0285	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CYA_0286	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CYA_0287	ENOG4105DWF	phosphomethylpyrimidine kinase
CYA_0292	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CYA_0296	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CYA_0297	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CYA_0301	ENOG4108VX5	3-methyladenine DNA glycosylase
CYA_0303	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CYA_0305	ENOG4105K70	DNA-binding protein
CYA_0309	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CYA_0310	ENOG4105CAS	nag kinase
CYA_0311	ENOG4105BZ1	(ABC) transporter
CYA_0313	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYA_0315	ENOG4105BZA	Phosphoglycerate kinase
CYA_0316	ENOG4105CVN	desaturase
CYA_0318	ENOG4108I5C	dEAD DEAH box helicase
CYA_0322	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CYA_0325	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CYA_0331	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
CYA_0332	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CYA_0333	ENOG4105CRK	lysyL-tRNA synthetase
CYA_0336	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CYA_0337	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CYA_0339	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CYA_0343	ENOG4105CFG	Acts as a chaperone (By similarity)
CYA_0348	ENOG410667J	hydrolase
CYA_0349	ENOG4105C4R	Atp-dependent dna helicase
CYA_0350	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
CYA_0352	ENOG4108UZX	fmn reductase
CYA_0354	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYA_0358	ENOG4107SVH	Potassium channel protein
CYA_0359	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CYA_0360	ENOG4108Z03	MAF-like protein
CYA_0361	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CYA_0362	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CYA_0365	ENOG4105EET	magnesium chelatase
CYA_0368	ENOG4105DFF	Rod shape-determining protein mreb
CYA_0369	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CYA_0371	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYA_0374	ENOG4105K64	Glycosyl transferase, family 2
CYA_0376	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CYA_0380	ENOG41063JG	Transcriptional regulator
CYA_0387	ENOG4105C89	phosphohexose isomerase
CYA_0388	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
CYA_0389	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYA_0392	ENOG4105CV8	reductase
CYA_0398	ENOG4105CP7	Triose-phosphate isomerase
CYA_0401	ENOG4105D0M	Protease HtpX homolog
CYA_0402	ENOG4105D7K	pfkb domain protein
CYA_0403	ENOG4105BZ1	(ABC) transporter
CYA_0405	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CYA_0406	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CYA_0409	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYA_0410	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYA_0411	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYA_0412	ENOG4105E50	uracil-dna glycosylase
CYA_0413	ENOG4105DWF	phosphomethylpyrimidine kinase
CYA_0414	ENOG4105E6N	shikimate quinate 5-dehydrogenase
CYA_0415	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
CYA_0420	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CYA_0421	ENOG4105ETX	regulatoR
CYA_0448	ENOG4107QJE	Chromosome Partitioning Protein
CYA_0456	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
CYA_0457	ENOG4105CHV	Transcription elongation factor NusA
CYA_0463	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CYA_0465	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CYA_0466	ENOG4105CGK	Exodeoxyribonuclease III
CYA_0467	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CYA_0469	ENOG4107Z6A	sulfate abc transporter permease
CYA_0470	ENOG4108IJ6	ABC transporter
CYA_0471	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CYA_0472	ENOG4105CD5	CoA-binding domain protein
CYA_0473	ENOG4108EKI	Dehydrogenase
CYA_0475	ENOG4105F1A	Pyruvate formate-lyase
CYA_0479	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CYA_0480	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CYA_0481	ENOG4105D74	hydrolase
CYA_0482	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CYA_0485	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CYA_0486	ENOG4105PGM	cation diffusion facilitator family transporter
CYA_0490	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CYA_0491	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CYA_0492	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
CYA_0496	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CYA_0499	ENOG4107QN2	dihydrolipoyl dehydrogenase
CYA_0500	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
CYA_0504	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CYA_0505	ENOG4107BJW	polysaccharide deacetylase
CYA_0510	ENOG4105CTK	cobaltochelatase, cobn subunit
CYA_0511	ENOG4105VFU	Rna-binding protein
CYA_0512	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CYA_0519	ENOG4108JYK	Dehydrogenase
CYA_0520	ENOG4105C8S	subunit m
CYA_0529	ENOG4108DIF	synthase (EC 4.2.1.75)
CYA_0530	ENOG4108IPT	Naphthoate synthase
CYA_0534	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYA_0535	ENOG4105CYW	agmatinase
CYA_0542	ENOG4105CBT	Fructose-1,6-bisphosphatase
CYA_0543	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CYA_0547	ENOG4105CEV	competence damage-inducible protein
CYA_0548	ENOG4108R6G	acetyltransferase
CYA_0554	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYA_0559	ENOG4105M85	Bola protein
CYA_0560	ENOG41086DT	Membrane protein of unknown function
CYA_0561	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CYA_0563	ENOG4105C6E	dna polymerase iii
CYA_0565	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CYA_0574	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CYA_0575	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CYA_0582	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CYA_0584	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CYA_0589	ENOG4105CHM	Aminotransferase
CYA_0591	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CYA_0597	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYA_0603	ENOG4105CQM	Urea amidohydrolase subunit alpha
CYA_0605	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CYA_0606	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CYA_0616	ENOG4105D7T	ABC transporter
CYA_0619	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CYA_0622	ENOG4105C12	Phosphoribosylglycinamide synthetase
CYA_0624	ENOG4105DCI	Phosphohydrolase
CYA_0627	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CYA_0630	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CYA_0632	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CYA_0634	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CYA_0637	ENOG4105BZU	Histidine kinase
CYA_0639	ENOG4105C8S	subunit m
CYA_0640	ENOG4105D65	subunit l
CYA_0644	ENOG4105YVZ	photosystem II
CYA_0646	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CYA_0647	ENOG4108UXN	response regulator
CYA_0651	ENOG4108N5B	2-phosphosulfolactate phosphatase
CYA_0659	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CYA_0661	ENOG4106QSA	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYA_0668	ENOG4105CVN	desaturase
CYA_0672	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYA_0673	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CYA_0675	ENOG4105CJW	magnesium transporter
CYA_0680	ENOG41083KH	UPF0102 protein
CYA_0681	ENOG4105M0M	Tetracycline resistance protein
CYA_0686	ENOG4105DRP	amino acid AbC transporter
CYA_0688	ENOG4108J01	L-aspartate oxidase
CYA_0692	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CYA_0693	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CYA_0697	ENOG4105DXN	mazG family
CYA_0702	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CYA_0703	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CYA_0705	ENOG4108Z61	cytochrome c-550
CYA_0707	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CYA_0708	ENOG41083KH	UPF0102 protein
CYA_0709	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CYA_0710	ENOG4105CDH	Citrulline--aspartate ligase
CYA_0713	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CYA_0714	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CYA_0718	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CYA_0721	ENOG4105EYH	Exonuclease
CYA_0724	ENOG4105CTK	cobaltochelatase, cobn subunit
CYA_0725	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CYA_0728	ENOG4105PWE	CRISPR-associated protein cas2
CYA_0744	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYA_0745	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CYA_0747	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYA_0749	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CYA_0753	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CYA_0756	ENOG4107SH3	glycosyl transferase, family 39
CYA_0761	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CYA_0762	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CYA_0765	ENOG4105CFP	Peptidase U32
CYA_0768	ENOG410902C	phosphohistidine phosphatase, SixA
CYA_0769	ENOG4105K63	Thioredoxin
CYA_0771	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CYA_0776	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CYA_0787	ENOG4105CFG	Acts as a chaperone (By similarity)
CYA_0788	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYA_0789	ENOG4105VFE	sira family
CYA_0790	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CYA_0795	ENOG4105BZU	Histidine kinase
CYA_0798	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CYA_0801	ENOG4107ZYR	domain protein
CYA_0802	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CYA_0803	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CYA_0804	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CYA_0818	ENOG4107791	aminotransferase class V
CYA_0822	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CYA_0829	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
CYA_0838	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CYA_0840	ENOG4105BZU	Histidine kinase
CYA_0846	ENOG4105CSM	endonuclease III
CYA_0847	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CYA_0848	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
CYA_0849	ENOG410828V	rubredoxin
CYA_0852	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CYA_0856	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYA_0861	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CYA_0869	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CYA_0870	ENOG4105FBA	Phospholipase Carboxylesterase
CYA_0877	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
CYA_0890	ENOG4108RBV	CRISPR-associated protein, Csx3 family
CYA_0891	ENOG4105D7T	ABC transporter
CYA_0895	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
CYA_0902	ENOG4105WN5	stage II sporulation protein
CYA_0907	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYA_0908	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CYA_0911	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CYA_0913	ENOG4105DZP	Membrane-associated zinc metalloprotease
CYA_0914	ENOG41083MR	nifu domain-containing protein
CYA_0916	ENOG4105BZU	Histidine kinase
CYA_0917	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CYA_0918	ENOG4108R85	Short chain dehydrogenase
CYA_0925	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
CYA_0927	ENOG4105ETX	regulatoR
CYA_0935	ENOG4108VPT	UPF0234 protein
CYA_0939	ENOG4105CJN	penicillin-binding protein
CYA_0940	ENOG4105K70	DNA-binding protein
CYA_0941	ENOG4107QZB	decarboxylase
CYA_0944	ENOG4107XKF	NMT1 THI5 Like Domain Protein
CYA_0945	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CYA_0946	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CYA_0947	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CYA_0948	ENOG4108IYU	L-aspartate oxidase
CYA_0950	ENOG4105C8M	UPF0272 protein
CYA_0952	ENOG4107QHM	Sulfite reductase
CYA_0959	ENOG41089BK	Glutamine amido-transferase
CYA_0960	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CYA_0964	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CYA_0967	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CYA_0969	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CYA_0971	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYA_0972	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CYA_0973	ENOG4106MP8	UPF0754 membrane protein
CYA_0976	ENOG4105CPC	Aldo Keto reductase
CYA_0978	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYA_0984	ENOG4105F04	LysR family Transcriptional regulator
CYA_0985	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CYA_1002	ENOG4105CXN	decarboxylase
CYA_1003	ENOG4105C37	(CBS) domain
CYA_1006	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CYA_1015	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYA_1023	ENOG4105VUV	UPF0367 protein
CYA_1024	ENOG4108JJB	ABC transporter
CYA_1026	ENOG4107SJW	iron permease, FTR1
CYA_1027	ENOG4105E0X	reductase
CYA_1028	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
CYA_1030	ENOG4105CD2	stage iii sporulation protein aa
CYA_1032	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CYA_1033	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYA_1034	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYA_1040	ENOG4108Z0R	Transferase
CYA_1049	ENOG4105ECP	epimerase
CYA_1050	ENOG4105DA5	(ABC) transporter
CYA_1051	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYA_1055	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYA_1056	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CYA_1059	ENOG4105CGH	5'-nucleotidase
CYA_1063	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CYA_1071	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CYA_1072	ENOG4105CJN	penicillin-binding protein
CYA_1077	ENOG4108KGH	TRANSCRIPTIONal
CYA_1078	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CYA_1079	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CYA_1081	ENOG4105DUM	transcriptional regulator, lysR family
CYA_1082	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CYA_1083	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CYA_1090	ENOG4105K8N	protein family UPF0079, ATPase
CYA_1092	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CYA_1095	ENOG4108RAV	Conserved protein
CYA_1097	ENOG4105CG3	alpha amylase, catalytic region
CYA_1101	ENOG4105C1Q	protoporphyrinogen oxidase
CYA_1108	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CYA_1114	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CYA_1116	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CYA_1120	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CYA_1122	ENOG4108X4D	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CYA_1123	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CYA_1125	ENOG41085FC	arsR family transcriptional regulator
CYA_1130	ENOG4108M8H	domain protein
CYA_1132	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CYA_1135	ENOG4108CKC	50S ribosomal protein L32
CYA_1136	ENOG4105D7V	transposase
CYA_1144	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CYA_1148	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CYA_1151	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CYA_1153	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYA_1154	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CYA_1157	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CYA_1159	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CYA_1160	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CYA_1161	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CYA_1162	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CYA_1163	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CYA_1164	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CYA_1165	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CYA_1166	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CYA_1167	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CYA_1168	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CYA_1169	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CYA_1170	ENOG410848H	50s ribosomal protein l29
CYA_1171	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CYA_1172	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CYA_1173	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CYA_1174	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CYA_1175	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CYA_1176	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CYA_1177	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CYA_1178	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CYA_1181	ENOG4105D7V	transposase
CYA_1186	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CYA_1188	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CYA_1189	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CYA_1193	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CYA_1194	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
CYA_1196	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
CYA_1202	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CYA_1203	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
CYA_1205	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
CYA_1206	ENOG4105C6T	cysteine synthase
CYA_1209	ENOG4108IUZ	ABC transporter
CYA_1214	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYA_1215	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
CYA_1216	ENOG4105CHM	Aminotransferase
CYA_1217	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CYA_1218	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CYA_1219	ENOG4108RXX	maleylacetoacetate isomerase
CYA_1220	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CYA_1221	ENOG4105JFG	SpoIID LytB domain protein
CYA_1224	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CYA_1227	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CYA_1228	ENOG4107GBW	cellulosome anchoring protein cohesin
CYA_1232	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CYA_1235	ENOG4108R0D	protein with myosin-like
CYA_1238	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CYA_1240	ENOG4105CRE	cytochrome C
CYA_1242	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CYA_1243	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYA_1252	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CYA_1253	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CYA_1256	ENOG4105C8T	Leucyl-tRNA synthetase
CYA_1259	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CYA_1264	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CYA_1266	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CYA_1268	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CYA_1269	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CYA_1270	ENOG4107QRG	dna polymerase iii
CYA_1271	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CYA_1272	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CYA_1273	ENOG41072GX	Peptidase M22 Glycoprotease
CYA_1274	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
CYA_1282	ENOG4105DRP	amino acid AbC transporter
CYA_1283	ENOG4105EZ7	amino acid ABC transporter
CYA_1284	ENOG4107QXX	ABC transporter
CYA_1285	ENOG4105CDA	abc transporter atp-binding protein
CYA_1290	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CYA_1294	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CYA_1298	ENOG4105MJ2	Competence protein
CYA_1299	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CYA_1300	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CYA_1301	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CYA_1302	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CYA_1303	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CYA_1308	ENOG4105CJP	fad dependent oxidoreductase
CYA_1319	ENOG4105CTK	cobaltochelatase, cobn subunit
CYA_1324	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CYA_1325	ENOG410686T	photosystem II reaction center protein N
CYA_1326	ENOG4105WIA	photosystem II reaction center protein H
CYA_1327	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CYA_1338	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CYA_1342	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
CYA_1343	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CYA_1353	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CYA_1361	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CYA_1362	ENOG4105C3M	thioredoxin reductase
CYA_1363	ENOG4105C5F	glutamine synthetase
CYA_1365	ENOG4105CHR	reductase
CYA_1368	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CYA_1369	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CYA_1370	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
CYA_1372	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CYA_1383	ENOG4105I3K	Ferric uptake regulator, Fur family
CYA_1386	ENOG4108K7V	UPF0284 protein
CYA_1392	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CYA_1394	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
CYA_1395	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CYA_1398	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CYA_1403	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYA_1404	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYA_1405	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CYA_1406	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CYA_1407	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CYA_1409	ENOG4107QVP	Dehydrogenase
CYA_1411	ENOG4108PWY	Carbohydrate-selective porin OprB
CYA_1412	ENOG4108PWY	Carbohydrate-selective porin OprB
CYA_1414	ENOG4105CHH	sulfate transporter
CYA_1417	ENOG4105BZW	Glycerate kinase
CYA_1418	ENOG4105MSA	Photosystem II reaction center W protein
CYA_1419	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CYA_1442	ENOG4105VN1	Heat shock protein
CYA_1445	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CYA_1446	ENOG41082HT	Binds the 23S rRNA (By similarity)
CYA_1447	ENOG4108UJD	30S ribosomal protein S9
CYA_1448	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CYA_1449	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CYA_1450	ENOG4108ZT0	50S ribosomal protein l17
CYA_1451	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CYA_1452	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CYA_1453	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CYA_1454	ENOG41067V7	50S ribosomal protein L36
CYA_1457	ENOG4105FF9	glycosyl transferase, family 39
CYA_1458	ENOG4105D9R	oxidoreductase
CYA_1460	ENOG4105CQC	Prephenate dehydratase
CYA_1463	ENOG4105D07	Signal peptide peptidase, SppA
CYA_1467	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CYA_1473	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CYA_1476	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CYA_1477	ENOG4108FN7	Aldo keto reductase
CYA_1479	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CYA_1484	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYA_1485	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
CYA_1490	ENOG4105EMN	RNA polymerase sigma factor
CYA_1495	ENOG4107U45	Cobalt transport protein
CYA_1504	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CYA_1505	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CYA_1508	ENOG4108YZA	Nitrogen regulatory protein pii
CYA_1515	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
CYA_1517	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CYA_1519	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CYA_1520	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CYA_1524	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
CYA_1525	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CYA_1531	ENOG4105DR5	peptidase
CYA_1533	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CYA_1535	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
CYA_1537	ENOG4105C8Y	Acetylornithine aminotransferase
CYA_1542	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CYA_1543	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CYA_1544	ENOG4105W1Y	Transcriptional regulator
CYA_1547	ENOG4107TS3	membrane protein, TerC
CYA_1548	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
CYA_1550	ENOG4105CDU	Replicative dna helicase
CYA_1551	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CYA_1552	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CYA_1553	ENOG4105C8U	phosphate abc transporter
CYA_1554	ENOG4105E2Z	phosphate ABC transporter (Permease
CYA_1555	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CYA_1559	ENOG4107RIQ	Sulfate adenylate transferase
CYA_1562	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CYA_1567	ENOG4107TTD	cytosine deaminase
CYA_1570	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYA_1573	ENOG4107YU2	histidine triad (hIT) protein
CYA_1576	ENOG4105CNW	domain protein
CYA_1577	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CYA_1582	ENOG4105UIB	(ABC) transporter
CYA_1583	ENOG4108JQ9	ABC transporter
CYA_1587	ENOG4105DZC	cytosine deaminase
CYA_1588	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
CYA_1591	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CYA_1593	ENOG4105D65	subunit l
CYA_1594	ENOG4105C8S	subunit m
CYA_1598	ENOG4105DB7	PHP domain protein
CYA_1599	ENOG4107SVH	Potassium channel protein
CYA_1602	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
CYA_1607	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
CYA_1611	ENOG4105KNY	Microcompartments protein
CYA_1612	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
CYA_1614	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
CYA_1615	ENOG4105MN7	Carbon dioxide concentrating mechanism protein
CYA_1619	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CYA_1621	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CYA_1622	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CYA_1624	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CYA_1626	ENOG4108JJB	ABC transporter
CYA_1627	ENOG4105DR5	peptidase
CYA_1630	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYA_1633	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
CYA_1636	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CYA_1638	ENOG4105CE9	30S ribosomal protein S2
CYA_1639	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CYA_1640	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CYA_1647	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CYA_1651	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CYA_1652	ENOG41084GG	50S ribosomal protein L33
CYA_1654	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CYA_1655	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CYA_1656	ENOG4105BZU	Histidine kinase
CYA_1657	ENOG4105BZU	Histidine kinase
CYA_1658	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CYA_1659	ENOG4105CNW	domain protein
CYA_1663	ENOG4105CVJ	phosphoglycerate mutase
CYA_1665	ENOG4107S2Z	UPF0761 membrane protein
CYA_1666	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CYA_1669	ENOG4105CKI	cobalamin synthesis protein
CYA_1673	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CYA_1675	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CYA_1678	ENOG4105CC5	ABC transporter
CYA_1679	ENOG4105DIK	(ABC) transporter
CYA_1680	ENOG4105DSE	periplasmic solute binding protein
CYA_1681	ENOG4105C9M	aspartyl-trna synthetase
CYA_1682	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CYA_1686	ENOG4108Z61	cytochrome c-550
CYA_1687	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
CYA_1689	ENOG4107SH3	glycosyl transferase, family 39
CYA_1690	ENOG4105W5Q	DNA repair protein (RadC
CYA_1691	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CYA_1693	ENOG4105CJW	magnesium transporter
CYA_1694	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CYA_1697	ENOG4105C01	Dihydroxy-acid dehydratase
CYA_1698	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CYA_1701	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CYA_1703	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CYA_1706	ENOG4105DC7	peptidase M24
CYA_1709	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CYA_1712	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CYA_1720	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CYA_1727	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CYA_1730	ENOG4105CXT	aspartate transcarbamylase
CYA_1732	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CYA_1733	ENOG4105C8U	phosphate abc transporter
CYA_1734	ENOG4105E2Z	phosphate ABC transporter (Permease
CYA_1735	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CYA_1738	ENOG4108PJD	permease
CYA_1740	ENOG4105M0M	Tetracycline resistance protein
CYA_1745	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
CYA_1747	ENOG4105CFH	Aspartokinase
CYA_1748	ENOG4108NSV	This is one of the two reaction center proteins of photosystem II
CYA_1749	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CYA_1755	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CYA_1756	ENOG4105MKQ	Monovalent cation H antiporter subunit C
CYA_1758	ENOG41090MY	MarR family Transcriptional regulator
CYA_1764	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CYA_1766	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CYA_1768	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CYA_1770	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CYA_1775	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CYA_1779	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CYA_1780	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CYA_1782	ENOG4107Z3D	50S ribosomal protein l10
CYA_1784	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CYA_1785	ENOG4107RIX	inner membrane protein translocase component YidC
CYA_1794	ENOG4108SGF	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYA_1796	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CYA_1797	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
CYA_1798	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CYA_1799	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
CYA_1803	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CYA_1806	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYA_1810	ENOG4105DJZ	UPF0182 protein
CYA_1811	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
CYA_1812	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CYA_1814	ENOG4105EEK	Polypeptide
CYA_1820	ENOG4107S73	homocitrate synthase
CYA_1821	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
CYA_1824	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
CYA_1826	ENOG4105C3J	Cysteine desulfurase
CYA_1827	ENOG4105WCA	Ferredoxin
CYA_1828	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
CYA_1831	ENOG4108NWW	ferritin dps family protein
CYA_1834	ENOG4105D0B	Nitrogenase protein alpha chain
CYA_1835	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
CYA_1836	ENOG4108UR2	Nitrogen fixation protein NifX
CYA_1837	ENOG4108VQE	nitrogen fixation protein
CYA_1839	ENOG4105R88	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
CYA_1844	ENOG4105X1Q	TOBE domain protein
CYA_1845	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CYA_1847	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CYA_1848	ENOG4105DJZ	UPF0182 protein
CYA_1849	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
CYA_1850	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CYA_1851	ENOG4105EEK	Polypeptide
CYA_1855	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CYA_1857	ENOG4107VFM	Dehydrogenase
CYA_1858	ENOG4105F38	ABC transporter, permease
CYA_1859	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CYA_1862	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CYA_1863	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CYA_1864	ENOG4105ERG	peptidase m48, ste24p
CYA_1866	ENOG4105D49	3-dehydroquinate synthase
CYA_1875	ENOG4105D4A	Cell wall formation (By similarity)
CYA_1876	ENOG4105DFU	Cell wall formation (By similarity)
CYA_1880	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CYA_1881	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CYA_1885	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CYA_1888	ENOG4105MYT	Heat shock protein
CYA_1892	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CYA_1893	ENOG4108JQ6	ABC transporter
CYA_1895	ENOG4105DR5	peptidase
CYA_1896	ENOG4105C8N	cysteinyl-tRNA synthetase
CYA_1899	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CYA_1903	ENOG4105DU0	nucleoside hydrolase
CYA_1904	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CYA_1905	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CYA_1906	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CYA_1908	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CYA_1915	ENOG4105C8S	subunit m
CYA_1917	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CYA_1918	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CYA_1919	ENOG4108JQ9	ABC transporter
CYA_1920	ENOG4108IV0	ABC, transporter
CYA_1921	ENOG4105C0Z	ABC transporter
CYA_1923	ENOG4105C32	Amino acid ABC transporter (Permease)
CYA_1924	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CYA_1926	ENOG4105E4C	Lytic transglycosylase catalytic
CYA_1929	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYA_1932	ENOG4105VGQ	Photosystem I subunit X
CYA_1933	ENOG4107JEG	This protein is a component of the reaction center of photosystem II (By similarity)
CYA_1936	ENOG4105EET	magnesium chelatase
CYA_1942	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CYA_1945	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CYA_1946	ENOG4108ZIT	Ferredoxin, 2FE-2S
CYA_1947	ENOG4105CMG	Carbohydrate kinase
CYA_1955	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYA_1957	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CYA_1959	ENOG4105D7V	transposase
CYA_1961	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CYA_1963	ENOG4107S8C	mandelate racemase muconate lactonizing
CYA_1964	ENOG4105C7K	acetolactate synthase
CYA_1965	ENOG4107QHF	type ii secretion system protein e
CYA_1966	ENOG4105CZX	twitching motility protein
CYA_1968	ENOG4107S52	alpha-2-macroglobulin domain protein
CYA_1969	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CYA_1974	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CYA_1975	ENOG41060D5	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CYA_1976	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CYA_1977	ENOG4105D7V	transposase
CYA_1981	ENOG4107QRI	Phosphoketolase
CYA_1982	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CYA_1988	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CYA_1991	ENOG4105UYK	outer membrane protein a
CYA_1994	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CYA_1995	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CYA_1996	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CYA_1999	ENOG4105W3H	MtN3 and saliva related transmembrane protein
CYA_2009	ENOG4105DXN	mazG family
CYA_2015	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CYA_2016	ENOG4105ESV	Glycosyl transferase, family 4
CYA_2018	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CYA_2021	ENOG4105C0P	Mg chelatase subunit ChlI
CYA_2022	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CYA_2027	ENOG4105ETX	regulatoR
CYA_2032	ENOG4105E0A	ABC, transporter
CYA_2033	ENOG4105EHG	Permease protein
CYA_2035	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CYA_2037	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYA_2040	ENOG41078GB	pbs lyase
CYA_2044	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYA_2045	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CYA_2048	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CYA_2050	ENOG4107QZ7	Cellulose synthase catalytic subunit
CYA_2051	ENOG4105K46	50S ribosomal protein l27
CYA_2052	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CYA_2056	ENOG4105J0C	
CYA_2057	ENOG4107VAM	peptidase, m28
CYA_2058	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
CYA_2062	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CYA_2063	ENOG4105D7V	transposase
CYA_2065	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CYA_2067	ENOG4105FFC	UPF0187 protein
CYA_2069	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
CYA_2071	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CYA_2072	ENOG4107RFW	hydrolase family 57
CYA_2073	ENOG4105C7K	acetolactate synthase
CYA_2083	ENOG4105CHH	sulfate transporter
CYA_2096	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CYA_2097	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
CYA_2098	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYA_2104	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CYA_2105	ENOG41082AN	stage II sporulation protein
CYA_2107	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CYA_2111	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CYA_2112	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CYA_2113	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CYA_2114	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYA_2115	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYA_2116	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYA_2117	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CYA_2119	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
CYA_2120	ENOG4105PA3	atp synthase
CYA_2123	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CYA_2125	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CYA_2126	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CYA_2134	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CYA_2138	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
CYA_2142	ENOG4108IJ0	Aspartate ammonia-lyase
CYA_2144	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CYA_2145	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYA_2146	ENOG4105D9P	serine threonine protein kinase
CYA_2147	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CYA_2152	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CYA_2155	ENOG4105CBS	Chea signal transduction histidine kinase
CYA_2155	ENOG4105CBS	Chea signal transduction histidine kinase
CYA_2161	ENOG4105M3Z	response regulator
CYA_2165	ENOG4105X25	
CYA_2169	ENOG4105CDU	Replicative dna helicase
CYA_2171	ENOG4105C1V	Peptidase, M16
CYA_2176	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
CYA_2177	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CYA_2179	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CYA_2180	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CYA_2181	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CYA_2184	ENOG4105BZU	Histidine kinase
CYA_2186	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CYA_2192	ENOG41084W5	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CYA_2199	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CYA_2214	ENOG41083EU	50s ribosomal protein l28
CYA_2216	ENOG4105D7Z	glutathione synthase
CYA_2218	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CYA_2223	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CYA_2224	ENOG4105CJ1	ABC, transporter
CYA_2225	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
CYA_2227	ENOG4108MAQ	allophycocyanin alpha
CYA_2230	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CYA_2231	ENOG4108IJ8	ABC transporter
CYA_2232	ENOG4105E90	ABC transporter
CYA_2233	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYA_2235	ENOG41073R8	VanW family
CYA_2236	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
CYA_2240	ENOG4108YZT	Adenosylcobinamide kinase
CYA_2243	ENOG4108V1U	phospholipid-binding protein
CYA_2247	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CYA_2253	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CYA_2257	ENOG4108RVA	ribokinase
CYA_2258	ENOG41080XM	UPF0145 protein
CYA_2259	ENOG4105CDY	transcriptional regulatory protein
CYA_2264	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CYA_2270	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CYA_2272	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CYA_2277	ENOG4105VPX	protein, conserved in bacteria
CYA_2279	ENOG41082B1	30S ribosomal protein S16
CYA_2282	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CYA_2283	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CYA_2291	ENOG4105C7Z	Conserved Protein
CYA_2292	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CYA_2296	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CYA_2297	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CYA_2298	ENOG4108VB1	regulatoR
CYA_2316	ENOG4108KXV	response regulator
CYA_2323	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CYA_2324	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CYA_2325	ENOG4105E66	phosphoriboisomerase A
CYA_2328	ENOG41080HI	glycine oxidase
CYA_2329	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CYA_2330	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
CYA_2334	ENOG4105JDN	Copper resistance protein
CYA_2335	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
CYA_2336	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CYA_2338	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CYA_2339	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CYA_2346	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CYA_2347	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CYA_2352	ENOG4105EB3	Histidine kinase
CYA_2353	ENOG4105EMU	Dehydrogenase
CYA_2356	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CYA_2358	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
CYA_2359	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
CYA_2360	ENOG4107QRP	cobalamin biosynthesis protein CobW
CYA_2366	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CYA_2367	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CYA_2372	ENOG4105C59	p-type ATPase
CYA_2376	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CYA_2378	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CYA_2379	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CYA_2382	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
CYA_2385	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
CYA_2386	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CYA_2387	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CYA_2389	ENOG41080E3	single-stranded DNA-binding protein
CYA_2394	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CYA_2405	ENOG4105F8J	Adenylate Guanylate cyclase
CYA_2410	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYA_2412	ENOG4105D38	putrescine abc transporter
CYA_2417	ENOG4105DUM	transcriptional regulator, lysR family
CYA_2419	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
CYA_2420	ENOG4105HHA	aminodeoxychorismate lyase
CYA_2421	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CYA_2429	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
CYA_2430	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
CYA_2432	ENOG4105C9X	ppx gppa phosphatase
CYA_2433	ENOG4105C22	threonyL-tRNA synthetase
CYA_2434	ENOG4108JQ9	ABC transporter
CYA_2437	ENOG4108JQ9	ABC transporter
CYA_2438	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CYA_2446	ENOG4105CXI	aluminum resistance protein
CYA_2455	ENOG4105E4F	Isochorismate synthase
CYA_2460	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
CYA_2461	ENOG4105D9R	oxidoreductase
CYA_2464	ENOG4108NWW	ferritin dps family protein
CYA_2467	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CYA_2474	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
CYA_2477	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CYA_2479	ENOG4105C32	Amino acid ABC transporter (Permease)
CYA_2481	ENOG4106KS4	Sulfatase
CYA_2484	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CYA_2485	ENOG4107VXZ	Hydrolase
CYA_2489	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CYA_2492	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
CYA_2493	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CYA_2495	ENOG4105CUT	histidyl-tRNA synthetase
CYA_2501	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CYA_2507	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CYA_2510	ENOG4105CK7	Sodium proline symporter
CYA_2513	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CYA_2519	ENOG4107WZZ	SMC domain protein
CYA_2521	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
CYA_2522	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
CYA_2527	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CYA_2529	ENOG4105CC5	ABC transporter
CYA_2531	ENOG4105FDK	ABC transporter
CYA_2532	ENOG4105DSE	periplasmic solute binding protein
CYA_2534	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CYA_2553	ENOG4105BZU	Histidine kinase
CYA_2554	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CYA_2560	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
CYA_2563	ENOG4105EGS	Mechanosensitive ion channel
CYA_2564	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CYA_2566	ENOG4105CKI	cobalamin synthesis protein
CYA_2568	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYA_2569	ENOG4105BZU	Histidine kinase
CYA_2570	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CYA_2579	ENOG4108Z4U	Ferredoxin
CYA_2581	ENOG4105D7V	transposase
CYA_2585	ENOG4105KI2	Urea amidohydrolase subunit beta
CYA_2590	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CYA_2591	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CYA_2592	ENOG4105JFG	SpoIID LytB domain protein
CYA_2593	ENOG4105DP8	Major facilitator superfamily MFS_1
CYA_2594	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CYA_2603	ENOG4108JH3	
CYA_2606	ENOG41065W4	chlorophyll a b binding light harvesting protein
CYA_2611	ENOG4107E2E	PKHD-type hydroxylase
CYA_2614	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CYA_2616	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CYA_2617	ENOG4105CVB	Vitamin K epoxide reductase
CYA_2618	ENOG4105BZU	Histidine kinase
CYA_2620	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CYA_2622	ENOG4105C0Z	ABC transporter
CYA_2623	ENOG4108IV0	ABC, transporter
CYA_2626	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CYA_2627	ENOG4108R99	pseudouridine synthase
CYA_2629	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CYA_2635	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CYA_2636	ENOG4105D7V	transposase
CYA_2643	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CYA_2644	ENOG4105ETX	regulatoR
CYA_2645	ENOG4108R6K	riboflavin synthase, subunit alpha
CYA_2646	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CYA_2647	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
CYA_2648	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CYA_2654	ENOG4105DDQ	anthranilate synthase
CYA_2658	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CYA_2663	ENOG4105CAT	Cytidine monophosphate kinase
CYA_2664	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
CYA_2665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CYA_2670	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CYA_2671	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CYA_2678	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CYA_2680	ENOG4105VF7	tolerance protein
CYA_2681	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CYA_2686	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
CYA_2688	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CYA_2696	ENOG4105KC4	UPF0296 protein
CYA_2697	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CYA_2699	ENOG4105ETX	regulatoR
CYA_2700	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CYA_2703	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
CYA_2713	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CYA_2715	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CYA_2727	ENOG4105ETX	regulatoR
CYA_2729	ENOG4105E2X	shikimate dehydrogenase
CYA_2732	ENOG4105C75	arginyL-tRNA synthetase
CYA_2734	ENOG4105BZJ	Electron transfer flavoprotein
CYA_2735	ENOG4105C10	Electron transfer flavoprotein
CYA_2736	ENOG4108VIA	integral membrane protein
CYA_2737	ENOG4108UNF	response regulator
CYA_2738	ENOG4105M3Z	response regulator
CYA_2742	ENOG4105CBS	Chea signal transduction histidine kinase
CYA_2742	ENOG4105CBS	Chea signal transduction histidine kinase
CYA_2744	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CYA_2746	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
CYA_2748	ENOG4105K6T	rare lipoprotein A
CYA_2751	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYA_2753	ENOG4105JFG	SpoIID LytB domain protein
CYA_2754	ENOG4108Z6B	deaminase
CYA_2762	ENOG4105D52	delta-aminolevulinic acid dehydratase
CYA_2765	ENOG4107KHP	This protein is a component of the reaction center of photosystem II (By similarity)
CYA_2769	ENOG4107TK4	histidinol-phosphate phosphatase
CYA_2782	ENOG4107RUE	extracellular solute-binding protein family 1
CYA_2783	ENOG4105EG2	ABC transporter, permease
CYA_2786	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CYA_2788	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CYA_2791	ENOG4105CZX	twitching motility protein
CYA_2792	ENOG4105EUJ	GTP cyclohydrolase i
CYA_2797	ENOG4105BZU	Histidine kinase
CYA_2801	ENOG4105K63	Thioredoxin
CYA_2803	ENOG4105C0H	protease
CYA_2807	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
CYA_2808	ENOG4105CQB	FAD linked oxidase domain protein
CYA_2809	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CYA_2810	ENOG4107SWE	Methyltransferase
CYA_2811	ENOG41084A0	50s ribosomal protein L35
CYA_2812	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CYA_2813	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CYA_2817	ENOG4105DBV	ornithine carbamoyltransferase
CYA_2820	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CYA_2822	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CYA_2826	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CYA_2828	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CYA_2830	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CYA_2832	ENOG4108HM4	ABC transporter
CYA_2834	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CYA_2836	ENOG4105BZU	Histidine kinase
CYA_2841	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CYA_2849	ENOG4105D3R	alkyl hydroperoxide reductase
CYA_2851	ENOG4105D64	Mechanosensitive ion channel
CYA_2852	ENOG4107XM9	(LipO)protein
CYA_2856	ENOG4108JQC	penicillin-binding protein 1A
CYA_2862	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CYA_2866	ENOG4108TQ9	Histidine kinase
CYA_2871	ENOG4105C59	p-type ATPase
CYA_2874	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CYA_2875	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
CYA_2876	ENOG4108UUM	single-stranded DNA-binding protein
CYA_2877	ENOG4105KXI	murein peptide amidase A
CYA_2882	ENOG4105CJ1	ABC, transporter
CYA_2883	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CYA_2884	ENOG4105K6T	rare lipoprotein A
CYA_2886	ENOG4105BZU	Histidine kinase
CYA_2888	ENOG4105C2J	ABC transporter
CYA_2890	ENOG4105CNI	cell division protein FtsW
CYA_2891	ENOG4107QI6	Cysteine desulfurase
CYA_2893	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CYA_2894	ENOG4105C8B	TIGR00159 family
CYA_2897	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CYA_2899	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CYA_2903	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CYA_2904	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)