locus-tag	class	description
KR100_00040	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
KR100_00075	ENOG4105CJ1	ABC, transporter
KR100_00085	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
KR100_00115	ENOG4105CHR	reductase
KR100_00120	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KR100_00245	ENOG4107QYX	exodeoxyribonuclease v alpha
KR100_00250	ENOG4107QYX	exodeoxyribonuclease v alpha
KR100_00300	ENOG4105DXN	mazG family
KR100_00310	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
KR100_00315	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
KR100_00320	ENOG4105CYW	agmatinase
KR100_00335	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
KR100_00345	ENOG4105C9M	aspartyl-trna synthetase
KR100_00350	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_00355	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
KR100_00360	ENOG4107U96	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
KR100_00365	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
KR100_00375	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
KR100_00395	ENOG4107QW3	Sucrose phosphorylase
KR100_00400	ENOG4105C3Q	Glycosyl transferase, family 2
KR100_00430	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
KR100_00445	ENOG4108IV0	ABC, transporter
KR100_00450	ENOG4105C0Z	ABC transporter
KR100_00460	ENOG4105C32	Amino acid ABC transporter (Permease)
KR100_00465	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
KR100_00470	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
KR100_00475	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
KR100_00480	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
KR100_00485	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
KR100_00490	ENOG4108YZ9	Urea amidohydrolase subunit gamma
KR100_00495	ENOG4105KI2	Urea amidohydrolase subunit beta
KR100_00500	ENOG4105CQM	Urea amidohydrolase subunit alpha
KR100_00540	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
KR100_00545	ENOG410838B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
KR100_00550	ENOG4107R3J	Transporter
KR100_00555	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
KR100_00575	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
KR100_00580	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
KR100_00590	ENOG4108535	NAD dependent epimerase/dehydratase family
KR100_00595	ENOG4108ZAF	Molybdopterin
KR100_00605	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
KR100_00620	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
KR100_00635	ENOG4108I0Q	anthranilate phosphoribosyltransferase
KR100_00650	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
KR100_00655	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_00675	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
KR100_00715	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
KR100_00720	ENOG4105CFG	Acts as a chaperone (By similarity)
KR100_00725	ENOG4105E2X	shikimate dehydrogenase
KR100_00735	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
KR100_00745	ENOG4105CDH	Citrulline--aspartate ligase
KR100_00760	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
KR100_00780	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
KR100_00785	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
KR100_00820	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
KR100_00830	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
KR100_00835	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
KR100_00850	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
KR100_00865	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
KR100_00875	ENOG4107SGM	protein serine threonine phosphatase
KR100_00880	ENOG4105CH7	arginosuccinase
KR100_00885	ENOG4105VFU	Rna-binding protein
KR100_00895	ENOG4105E0X	reductase
KR100_00900	ENOG4105CBX	hi0933 family
KR100_00910	ENOG4105CZX	twitching motility protein
KR100_00915	ENOG4107QHF	type ii secretion system protein e
KR100_00920	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KR100_00925	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
KR100_00935	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
KR100_00940	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
KR100_00945	ENOG4105D4A	Cell wall formation (By similarity)
KR100_00950	ENOG4105DFU	Cell wall formation (By similarity)
KR100_00960	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
KR100_00970	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
KR100_00975	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
KR100_00980	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
KR100_01050	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
KR100_01055	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
KR100_01070	ENOG4105CJN	penicillin-binding protein
KR100_01080	ENOG4105CMR	udp-glucose 4-epimerase
KR100_01090	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
KR100_01105	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
KR100_01110	ENOG41084A0	50s ribosomal protein L35
KR100_01115	ENOG4105JFG	SpoIID LytB domain protein
KR100_01125	ENOG4105C6E	dna polymerase iii
KR100_01135	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
KR100_01140	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR100_01145	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
KR100_01150	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
KR100_01155	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
KR100_01205	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
KR100_01225	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
KR100_01230	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
KR100_01235	ENOG4106YF5	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
KR100_01240	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
KR100_01315	ENOG4105C5E	polysaccharide biosynthesis protein
KR100_01385	ENOG4108IUS	Transketolase
KR100_01390	ENOG4108HHA	Transketolase
KR100_01405	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
KR100_01415	ENOG4105CA9	Pyruvate kinase
KR100_01445	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
KR100_01450	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
KR100_01485	ENOG4105E2K	Glycosyl transferase (Group 1
KR100_01500	ENOG4105E2K	Glycosyl transferase (Group 1
KR100_01525	ENOG4108JJA	ABC, transporter
KR100_01575	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
KR100_01600	ENOG4105D7W	serine acetyltransferase
KR100_01605	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
KR100_01615	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
KR100_01620	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
KR100_01635	ENOG41086BQ	Protein CrcB homolog
KR100_01640	ENOG4107KCI	Protein CrcB homolog
KR100_01650	ENOG4105CJW	magnesium transporter
KR100_01655	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_01670	ENOG4105BZS	acriflavin resistance protein
KR100_01685	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
KR100_01695	ENOG4105F8C	transglutaminase domain-containing protein
KR100_01705	ENOG4105CEN	a g-specific adenine glycosylase
KR100_01710	ENOG4105D7K	pfkb domain protein
KR100_01715	ENOG4105K8N	protein family UPF0079, ATPase
KR100_01720	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
KR100_01725	ENOG4107T5V	SNARE associated Golgi
KR100_01760	ENOG4105CRK	lysyL-tRNA synthetase
KR100_01780	ENOG41067HS	methyltransferase
KR100_01800	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
KR100_01825	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
KR100_01830	ENOG4105CV1	Transketolase (EC 2.2.1.1)
KR100_01840	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
KR100_01845	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
KR100_01850	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
KR100_01855	ENOG4105C30	Nad-dependent epimerase dehydratase
KR100_01860	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
KR100_01865	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
KR100_01870	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
KR100_01880	ENOG4105EYW	Ion transport protein
KR100_01885	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
KR100_02055	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
KR100_02065	ENOG4107QRI	Phosphoketolase
KR100_02095	ENOG4105EU8	FAD linked oxidase domain protein
KR100_02105	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
KR100_02115	ENOG4108HMX	isocitrate dehydrogenase (NADP)
KR100_02125	ENOG4108HMX	isocitrate dehydrogenase (NADP)
KR100_02140	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
KR100_02165	ENOG4107EF8	Glycosyl transferase (Group 1
KR100_02170	ENOG4107TAE	Glycosyl transferase (Group 1
KR100_02175	ENOG4107TAE	Glycosyl transferase (Group 1
KR100_02180	ENOG4107T8Q	Glycosyl transferase (Group 1
KR100_02205	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
KR100_02220	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
KR100_02225	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
KR100_02230	ENOG4105C2X	Arabinose 5-phosphate isomerase
KR100_02235	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KR100_02245	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
KR100_02250	ENOG4105CMR	udp-glucose 4-epimerase
KR100_02260	ENOG4108JJA	ABC, transporter
KR100_02275	ENOG4105CGN	Glycosyl transferase (Group 1
KR100_02280	ENOG4105CUT	histidyl-tRNA synthetase
KR100_02290	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
KR100_02300	ENOG4105YEU	This protein is a component of the reaction center of photosystem II (By similarity)
KR100_02305	ENOG4107JBH	Required for PSII activity (By similarity)
KR100_02310	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
KR100_02315	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
KR100_02320	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
KR100_02325	ENOG410828V	rubredoxin
KR100_02330	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KR100_02335	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR100_02340	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KR100_02345	ENOG4105CHW	UPF0052 protein
KR100_02350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KR100_02360	ENOG4105EET	magnesium chelatase
KR100_02365	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KR100_02370	ENOG4108YZ4	nudix hydrolase
KR100_02375	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
KR100_02385	ENOG4105QNJ	serralysin (EC 3.4.24.40)
KR100_02420	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
KR100_02425	ENOG4105FFC	UPF0187 protein
KR100_02430	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
KR100_02465	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
KR100_02475	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
KR100_02480	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
KR100_02490	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
KR100_02495	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
KR100_02505	ENOG4105C37	(CBS) domain
KR100_02525	ENOG4106815	This protein is a component of the reaction center of photosystem II (By similarity)
KR100_02530	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
KR100_02545	ENOG41062D9	Histidine kinase
KR100_02560	ENOG4105DC1	bifunctional purine biosynthesis protein purh
KR100_02575	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
KR100_02585	ENOG4105PW4	Sugar fermentation stimulation protein homolog
KR100_02620	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
KR100_02625	ENOG4105ESV	Glycosyl transferase, family 4
KR100_02630	ENOG4105CEV	competence damage-inducible protein
KR100_02635	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
KR100_02655	ENOG4107M19	This protein is a component of the reaction center of photosystem II (By similarity)
KR100_02665	ENOG410686T	photosystem II reaction center protein N
KR100_02670	ENOG4105WIA	photosystem II reaction center protein H
KR100_02675	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
KR100_02680	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
KR100_02695	ENOG4108R0D	protein with myosin-like
KR100_02700	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
KR100_02705	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
KR100_02710	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
KR100_02725	ENOG4108S64	thioredoxin-like protein txlA
KR100_02745	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
KR100_02750	ENOG4105RD7	BadF BadG BcrA BcrD
KR100_02760	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
KR100_02780	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
KR100_02805	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
KR100_02825	ENOG4108VX5	3-methyladenine DNA glycosylase
KR100_02830	ENOG4105CXT	aspartate transcarbamylase
KR100_02870	ENOG4105CPJ	photosystem II manganese-stabilizing
KR100_02875	ENOG4107RIQ	Sulfate adenylate transferase
KR100_02885	ENOG4108UHU	Aldolase
KR100_02895	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
KR100_02910	ENOG4105C7K	acetolactate synthase
KR100_02930	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
KR100_02935	ENOG4105E0C	molybdate abc transporter
KR100_02940	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
KR100_02945	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
KR100_02960	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
KR100_02965	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
KR100_02980	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
KR100_02990	ENOG4105CQC	Prephenate dehydratase
KR100_03005	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
KR100_03010	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
KR100_03015	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
KR100_03020	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
KR100_03025	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
KR100_03050	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
KR100_03060	ENOG4108PWY	Carbohydrate-selective porin OprB
KR100_03080	ENOG4108TGK	Low-potential electron donor to a number of redox enzymes (By similarity)
KR100_03085	ENOG4105C3M	thioredoxin reductase
KR100_03095	ENOG41065W4	chlorophyll a b binding light harvesting protein
KR100_03105	ENOG4106BTU	phycobilisome rod-core linker polypeptide
KR100_03125	ENOG4108PWY	Carbohydrate-selective porin OprB
KR100_03140	ENOG4105E4R	Precorrin-3B C17-methyltransferase
KR100_03150	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
KR100_03155	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
KR100_03190	ENOG4108W6I	photosystem I reaction center protein subunit XI
KR100_03200	ENOG4105CKK	Glycosyl transferase, family 2
KR100_03220	ENOG4105EYW	Ion transport protein
KR100_03230	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
KR100_03240	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
KR100_03245	ENOG41082HT	Binds the 23S rRNA (By similarity)
KR100_03250	ENOG4108UJD	30S ribosomal protein S9
KR100_03255	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
KR100_03260	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
KR100_03265	ENOG4108ZT0	50S ribosomal protein l17
KR100_03270	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR100_03275	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
KR100_03280	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KR100_03290	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
KR100_03295	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
KR100_03300	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
KR100_03305	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
KR100_03310	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
KR100_03315	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
KR100_03320	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
KR100_03325	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KR100_03330	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
KR100_03335	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
KR100_03340	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
KR100_03345	ENOG410848H	50s ribosomal protein l29
KR100_03350	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
KR100_03355	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
KR100_03360	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
KR100_03365	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
KR100_03370	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KR100_03375	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
KR100_03380	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
KR100_03385	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
KR100_03390	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR100_03400	ENOG4105CD2	stage iii sporulation protein aa
KR100_03415	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
KR100_03440	ENOG4105EWK	phytoene
KR100_03465	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
KR100_03475	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
KR100_03480	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
KR100_03495	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
KR100_03500	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
KR100_03520	ENOG4105CNI	cell division protein FtsW
KR100_03530	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
KR100_03550	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
KR100_03585	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
KR100_03595	ENOG4105CAT	Cytidine monophosphate kinase
KR100_03605	ENOG41078GB	pbs lyase
KR100_03625	ENOG4108KKY	Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin (By similarity)
KR100_03645	ENOG4108RIN	C-phycoerythrin class I beta chain
KR100_03650	ENOG4108REV	C-phycoerythrin class I alpha chain
KR100_03685	ENOG4106QDP	C-phycoerythrin class II alpha chain
KR100_03690	ENOG4106JQX	C-phycoerythrin class II beta chain
KR100_03715	ENOG4108U42	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
KR100_03755	ENOG4106BTU	phycobilisome rod-core linker polypeptide
KR100_03810	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
KR100_03820	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
KR100_03825	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
KR100_03835	ENOG4105YVZ	photosystem II
KR100_03845	ENOG41069TS	Photosystem II reaction center protein M
KR100_03865	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
KR100_03870	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
KR100_03890	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
KR100_03900	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
KR100_03905	ENOG4105DCI	Phosphohydrolase
KR100_03915	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
KR100_03920	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
KR100_03930	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
KR100_03935	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
KR100_03945	ENOG4105C9U	ATP-dependent DNA helicase RecQ
KR100_03950	ENOG41068JE	domain protein
KR100_03955	ENOG4105C26	Dehydrogenase
KR100_03965	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
KR100_03970	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
KR100_03990	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
KR100_04060	ENOG4105CHH	sulfate transporter
KR100_04065	ENOG4105CVB	Vitamin K epoxide reductase
KR100_04075	ENOG4105D52	delta-aminolevulinic acid dehydratase
KR100_04100	ENOG4108IJ9	(ABC) transporter
KR100_04105	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KR100_04120	ENOG4105C5H	ABC transporter
KR100_04130	ENOG4105CHF	Glutathione S-transferase
KR100_04135	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
KR100_04160	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
KR100_04430	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
KR100_04435	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
KR100_04440	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
KR100_04445	ENOG4105DZP	Membrane-associated zinc metalloprotease
KR100_04450	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
KR100_04470	ENOG4107RIX	inner membrane protein translocase component YidC
KR100_04480	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
KR100_04510	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
KR100_04530	ENOG4105K63	Thioredoxin
KR100_04535	ENOG4105CHM	Aminotransferase
KR100_04540	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
KR100_04545	ENOG4105DR5	peptidase
KR100_04550	ENOG4105ETX	regulatoR
KR100_04560	ENOG4105BZU	Histidine kinase
KR100_04565	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
KR100_04570	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
KR100_04575	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR100_04580	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
KR100_04595	ENOG4108K7V	UPF0284 protein
KR100_04640	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
KR100_04645	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
KR100_04665	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
KR100_04670	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
KR100_04695	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
KR100_04710	ENOG4105C9X	ppx gppa phosphatase
KR100_04725	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
KR100_04730	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
KR100_04735	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
KR100_04740	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
KR100_04755	ENOG4105F23	Fibronectin-binding protein
KR100_04760	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
KR100_04765	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
KR100_04775	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
KR100_04780	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR100_04785	ENOG4105CZX	twitching motility protein
KR100_04815	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
KR100_04835	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
KR100_04895	ENOG4108VPT	UPF0234 protein
KR100_04935	ENOG4105KG3	cytidine deaminase
KR100_04945	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
KR100_04950	ENOG4105CQB	FAD linked oxidase domain protein
KR100_04955	ENOG4105CGK	Exodeoxyribonuclease III
KR100_04975	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
KR100_04980	ENOG4105C8M	UPF0272 protein
KR100_05010	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KR100_05025	ENOG4105CKI	cobalamin synthesis protein
KR100_05030	ENOG4105KZX	Pterin carbinolamine dehydratase
KR100_05050	ENOG4105CTD	carboxy-peptidase
KR100_05055	ENOG4105F0N	pyrophosphate phospho-hydrolase
KR100_05070	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
KR100_05115	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_05140	ENOG4105CAS	nag kinase
KR100_05175	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
KR100_05185	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
KR100_05200	ENOG4105F0N	pyrophosphate phospho-hydrolase
KR100_05230	ENOG4105CVJ	phosphoglycerate mutase
KR100_05245	ENOG4105CJN	penicillin-binding protein
KR100_05250	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
KR100_05260	ENOG4105SS7	PucC protein
KR100_05270	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
KR100_05280	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
KR100_05285	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
KR100_05295	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
KR100_05300	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
KR100_05310	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR100_05315	ENOG4105C7K	acetolactate synthase
KR100_05340	ENOG4105DZ0	fad dependent oxidoreductase
KR100_05355	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
KR100_05365	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
KR100_05370	ENOG4105E6N	shikimate quinate 5-dehydrogenase
KR100_05375	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
KR100_05390	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
KR100_05400	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
KR100_05430	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
KR100_05440	ENOG4105NF4	modulator of drug activity
KR100_05455	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
KR100_05460	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
KR100_05485	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
KR100_05490	ENOG4105KNY	Microcompartments protein
KR100_05495	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
KR100_05500	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
KR100_05525	ENOG4105KNY	Microcompartments protein
KR100_05535	ENOG4105C8S	subunit m
KR100_05560	ENOG4106F1P	AAA ATPase, central domain protein
KR100_05575	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
KR100_05590	ENOG4108Z03	MAF-like protein
KR100_05600	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
KR100_05605	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
KR100_05615	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
KR100_05620	ENOG4105D64	Mechanosensitive ion channel
KR100_05625	ENOG4105C8N	cysteinyl-tRNA synthetase
KR100_05640	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
KR100_05645	ENOG4105C3G	gtp-binding protein
KR100_05670	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
KR100_05675	ENOG4108J59	Extracellular solute-binding protein, family 5
KR100_05700	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
KR100_05780	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
KR100_05800	ENOG4106FVC	RNA methyltransferase
KR100_05810	ENOG4106H78	methyltransferase
KR100_05815	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
KR100_05820	ENOG4105K63	Thioredoxin
KR100_05830	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
KR100_05840	ENOG4108JT6	LycopEne
KR100_05845	ENOG4107RFW	hydrolase family 57
KR100_05850	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
KR100_05855	ENOG4105DRS	transport system, permease
KR100_05895	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
KR100_05935	ENOG4108ZM9	phosphoglycerate mutase
KR100_05950	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
KR100_05970	ENOG4107SC0	ferredoxin--NADP reductase
KR100_05985	ENOG4105BZU	Histidine kinase
KR100_06005	ENOG4105CD8	aminopeptidase N
KR100_06060	ENOG4105EYW	Ion transport protein
KR100_06085	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
KR100_06100	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
KR100_06155	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
KR100_06185	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
KR100_06200	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
KR100_06205	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR100_06210	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
KR100_06215	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
KR100_06245	ENOG41090A1	ferritin
KR100_06250	ENOG4108PWY	Carbohydrate-selective porin OprB
KR100_06255	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
KR100_06270	ENOG4107R1Y	fructose-bisphosphate aldolase
KR100_06285	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
KR100_06305	ENOG4105D64	Mechanosensitive ion channel
KR100_06315	ENOG4105KBH	arsR family transcriptional regulator
KR100_06340	ENOG4105CSR	polyphosphate kinase 2
KR100_06345	ENOG4105E0F	Histidine kinase
KR100_06355	ENOG4108W6I	photosystem I reaction center protein subunit XI
KR100_06380	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
KR100_06410	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
KR100_06440	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
KR100_06455	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR100_06465	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
KR100_06470	ENOG4105CTK	cobaltochelatase, cobn subunit
KR100_06485	ENOG4105CP7	Triose-phosphate isomerase
KR100_06495	ENOG4105BZ1	(ABC) transporter
KR100_06505	ENOG4105BZG	amino acid carrier protein
KR100_06560	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
KR100_06570	ENOG4105CHH	sulfate transporter
KR100_06585	ENOG4107QXX	ABC transporter
KR100_06590	ENOG4105EZ7	amino acid ABC transporter
KR100_06595	ENOG4105DRP	amino acid AbC transporter
KR100_06600	ENOG4105CDA	abc transporter atp-binding protein
KR100_06725	ENOG4105CVG	Homoserine O-transsuccinylase
KR100_06730	ENOG4108IQK	o-acetylhomoserine
KR100_06845	ENOG4105CYM	Glutathione S-transferase
KR100_06895	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
KR100_06910	ENOG4107XWZ	ferric uptake regulator
KR100_06915	ENOG4105WH1	Two component transcriptional regulator luxr family
KR100_06925	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
KR100_06975	ENOG4105DGU	Histone deacetylase
KR100_07240	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
KR100_07255	ENOG4108Z0R	Transferase
KR100_07260	ENOG41076WT	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II (By similarity)
KR100_07265	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
KR100_07320	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
KR100_07340	ENOG4107S1Q	Phosphatase
KR100_07345	ENOG4105DSY	exodeoxyribonuclease V, gamma
KR100_07355	ENOG4107QYX	exodeoxyribonuclease v alpha
KR100_07360	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
KR100_07365	ENOG4105C1J	atp-dependent rna helicase
KR100_07380	ENOG4105VFU	Rna-binding protein
KR100_07390	ENOG4105BZ1	(ABC) transporter
KR100_07415	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
KR100_07435	ENOG4105WH1	Two component transcriptional regulator luxr family
KR100_07440	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
KR100_07475	ENOG4105C72	UPF0176 protein
KR100_07490	ENOG4108M26	parallel beta-helix repeat protein
KR100_07495	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
KR100_07500	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
KR100_07505	ENOG4105C8B	TIGR00159 family
KR100_07530	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
KR100_07555	ENOG4105E18	UPF0276 protein
KR100_07560	ENOG4105K6T	rare lipoprotein A
KR100_07565	ENOG4105CXN	decarboxylase
KR100_07570	ENOG4108JJA	ABC, transporter
KR100_07575	ENOG4108JJA	ABC, transporter
KR100_07605	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
KR100_07615	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KR100_07620	ENOG4105EB3	Histidine kinase
KR100_07655	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
KR100_07715	ENOG4105DIK	(ABC) transporter
KR100_07740	ENOG4108PJD	permease
KR100_07765	ENOG4105CAQ	asparagine synthetase
KR100_07770	ENOG4105CXT	aspartate transcarbamylase
KR100_07840	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
KR100_07845	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
KR100_07930	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
KR100_07935	ENOG4108IPT	Naphthoate synthase
KR100_07940	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
KR100_07945	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
KR100_07965	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
KR100_08015	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
KR100_08025	ENOG4108N5B	2-phosphosulfolactate phosphatase
KR100_08035	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
KR100_08040	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
KR100_08050	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
KR100_08060	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
KR100_08070	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR100_08075	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
KR100_08110	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
KR100_08120	ENOG4105BZ1	(ABC) transporter
KR100_08130	ENOG4108I0Q	anthranilate phosphoribosyltransferase
KR100_08135	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
KR100_08145	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KR100_08165	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
KR100_08180	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
KR100_08210	ENOG4107SVH	Potassium channel protein
KR100_08215	ENOG41061P3	phosphosulfolactate synthase
KR100_08220	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
KR100_08230	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
KR100_08240	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
KR100_08245	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
KR100_08300	ENOG4105D49	3-dehydroquinate synthase
KR100_08305	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
KR100_08310	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
KR100_08380	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
KR100_08385	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR100_08395	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
KR100_08440	ENOG4107TS3	membrane protein, TerC
KR100_08455	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
KR100_08475	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
KR100_08520	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
KR100_08525	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
KR100_08540	ENOG41068G9	50S ribosomal protein L32
KR100_08545	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
KR100_08550	ENOG4105DJZ	UPF0182 protein
KR100_08570	ENOG4105DR5	peptidase
KR100_08585	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
KR100_08630	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
KR100_08640	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
KR100_08645	ENOG41084GG	50S ribosomal protein L33
KR100_08650	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
KR100_08655	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
KR100_08680	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_08690	ENOG4105JFG	SpoIID LytB domain protein
KR100_08725	ENOG4105CTK	cobaltochelatase, cobn subunit
KR100_08735	ENOG4105DB7	PHP domain protein
KR100_08745	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
KR100_08755	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
KR100_08765	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
KR100_08790	ENOG4107QI6	Cysteine desulfurase
KR100_08795	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
KR100_08825	ENOG4105C8T	Leucyl-tRNA synthetase
KR100_08835	ENOG4105C89	phosphohexose isomerase
KR100_08890	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
KR100_08895	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
KR100_08905	ENOG4108ZCU	PPIases accelerate the folding of proteins
KR100_08910	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
KR100_08915	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KR100_08930	ENOG4105DVC	DnaJ domain protein
KR100_08935	ENOG4108KBA	Acts as a chaperone (By similarity)
KR100_08940	ENOG4105C8U	phosphate abc transporter
KR100_08945	ENOG4105E2Z	phosphate ABC transporter (Permease
KR100_08950	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
KR100_08970	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
KR100_08980	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
KR100_08985	ENOG41083EU	50s ribosomal protein l28
KR100_08990	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR100_09000	ENOG4107T3P	ABC, transporter
KR100_09035	ENOG4105VGQ	Photosystem I subunit X
KR100_09040	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
KR100_09045	ENOG4105C7B	Threonine dehydratase
KR100_09055	ENOG4108VIA	integral membrane protein
KR100_09100	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
KR100_09105	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
KR100_09120	ENOG4107T9Q	phosphonate abc transporter
KR100_09125	ENOG4105D5T	phosphonate abc transporter
KR100_09155	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
KR100_09165	ENOG4108JJB	ABC transporter
KR100_09170	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
KR100_09190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
KR100_09195	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
KR100_09200	ENOG4107VC8	ATP cone domain protein
KR100_09290	ENOG4108URH	decarboxylase
KR100_09335	ENOG4107QRP	cobalamin biosynthesis protein CobW
KR100_09340	ENOG4105N7N	Pentapeptide repeat-containing protein
KR100_09345	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
KR100_09355	ENOG4105C01	Dihydroxy-acid dehydratase
KR100_09380	ENOG4107RSS	Hydrogenase accessory protein HypB
KR100_09385	ENOG41080Y1	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
KR100_09400	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
KR100_09405	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
KR100_09410	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
KR100_09415	ENOG4105CBT	Fructose-1,6-bisphosphatase
KR100_09455	ENOG4105CRE	cytochrome C
KR100_09470	ENOG4108IUZ	ABC transporter
KR100_09490	ENOG4105CFP	Peptidase U32
KR100_09510	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
KR100_09515	ENOG4107QHM	Sulfite reductase
KR100_09535	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
KR100_09540	ENOG4105CE9	30S ribosomal protein S2
KR100_09545	ENOG4107R51	Glycosyl transferase, family 2
KR100_09555	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
KR100_09565	ENOG4105CW7	secretion protein, HlyD family
KR100_09570	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
KR100_09595	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
KR100_09600	ENOG4105BZ4	penicillin-binding protein
KR100_09615	ENOG4108Z6B	deaminase
KR100_09620	ENOG4105C5R	Aminotransferase
KR100_09625	ENOG4108TCG	allophycocyanin beta subunit
KR100_09630	ENOG4105C5F	glutamine synthetase
KR100_09635	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
KR100_09665	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
KR100_09670	ENOG4105MSA	Photosystem II reaction center W protein
KR100_09675	ENOG4105DSF	transport protein
KR100_09710	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
KR100_09715	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
KR100_09735	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
KR100_09740	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
KR100_09815	ENOG4107JDS	UPF0102 protein
KR100_09895	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
KR100_09910	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
KR100_09940	ENOG4105KT5	UmuD protein
KR100_09945	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
KR100_09970	ENOG4107T0X	DNA ligase
KR100_09980	ENOG4107QRT	dEAD DEAH box helicase
KR100_10025	ENOG4108Z5K	methylglyoxal synthase
KR100_10035	ENOG4105CAH	Chromate
KR100_10065	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
KR100_10130	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
KR100_10175	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
KR100_10295	ENOG4105DSE	periplasmic solute binding protein
KR100_10440	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
KR100_10450	ENOG4105DVW	rieske (2Fe-2S)
KR100_10495	ENOG4105H3G	oxidoreductase
KR100_10500	ENOG4105VFU	Rna-binding protein
KR100_10535	ENOG4105WH1	Two component transcriptional regulator luxr family
KR100_10545	ENOG4107VAM	peptidase, m28
KR100_10575	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
KR100_10710	ENOG410848W	30S ribosomal protein S21
KR100_10725	ENOG4105JZI	cytochrome P450
KR100_10890	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
KR100_10900	ENOG4105PGM	cation diffusion facilitator family transporter
KR100_10915	ENOG4105C31	Tryptophanyl-tRNA synthetase
KR100_10930	ENOG4105C22	threonyL-tRNA synthetase
KR100_10940	ENOG4105CHC	glucokinase (EC 2.7.1.2)
KR100_10945	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
KR100_10950	ENOG4105C8S	subunit m
KR100_10955	ENOG4105DGW	oligopeptidase A
KR100_10970	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
KR100_11010	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
KR100_11015	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
KR100_11025	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
KR100_11050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
KR100_11065	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
KR100_11080	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_11130	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
KR100_11140	ENOG41069EW	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR100_11160	ENOG4105EKE	dihydroorotase
KR100_11165	ENOG4105CHH	sulfate transporter
KR100_11230	ENOG4105DC8	reductase
KR100_11250	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
KR100_11255	ENOG4105C0H	protease
KR100_11265	ENOG4106WTF	Glycosyl transferase, family 2
KR100_11275	ENOG4105BZ1	(ABC) transporter
KR100_11280	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
KR100_11285	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
KR100_11290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KR100_11395	ENOG4105CSV	Glutaminase
KR100_11400	ENOG4105CSV	Glutaminase
KR100_11460	ENOG4105DBV	ornithine carbamoyltransferase
KR100_11475	ENOG4108RAV	Conserved protein
KR100_11530	ENOG4105ETX	regulatoR
KR100_11535	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
KR100_11560	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
KR100_11565	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
KR100_11575	ENOG4105DTN	riboflavin biosynthesis protein ribF
KR100_11585	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
KR100_11590	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
KR100_11605	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
KR100_11615	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
KR100_11650	ENOG4105TW1	Carbohydrate-selective porin OprB
KR100_11660	ENOG4105HFZ	Membrane
KR100_11670	ENOG41082B1	30S ribosomal protein S16
KR100_11675	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KR100_11685	ENOG4108JYK	Dehydrogenase
KR100_11690	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR100_11695	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
KR100_11700	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
KR100_11730	ENOG4105DK0	Indole-3-glycerol phosphate synthase
KR100_11755	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
KR100_11760	ENOG4105C8Y	Acetylornithine aminotransferase
KR100_11770	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
KR100_11775	ENOG4105N7N	Pentapeptide repeat-containing protein
KR100_11805	ENOG4105DTQ	mandelate racemase muconate lactonizing
KR100_11810	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
KR100_11815	ENOG4105CPF	Cell wall formation (By similarity)
KR100_11830	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
KR100_11860	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR100_11865	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR100_11870	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
KR100_11885	ENOG4105D3Q	Sugar transferase
KR100_11945	ENOG4108C33	Resolvase
KR100_11975	ENOG4105K4I	Scp-like extracellular
KR100_12015	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
KR100_12025	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
KR100_12035	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
KR100_12045	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
KR100_12050	ENOG4108JQC	penicillin-binding protein 1A
KR100_12060	ENOG41080UX	Methyltransferase
KR100_12070	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
KR100_12090	ENOG41062D9	Histidine kinase
KR100_12120	ENOG4105ETX	regulatoR
KR100_12130	ENOG4108ZUW	Major pilin subunit
KR100_12185	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
KR100_12200	ENOG4105DWT	malate dehydrogenase (quinone)
KR100_12205	ENOG41083MR	nifu domain-containing protein
KR100_12245	ENOG4105C8J	)-transporter
KR100_12250	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
KR100_12255	ENOG4105NZG	Ferredoxin
KR100_12265	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KR100_12270	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KR100_12275	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KR100_12300	ENOG4105C3M	thioredoxin reductase
KR100_12305	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
KR100_12325	ENOG4108R99	pseudouridine synthase
KR100_12355	ENOG4106HB6	Alpha beta hydrolase
KR100_12365	ENOG4105K4I	Scp-like extracellular
KR100_12375	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
KR100_12380	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
KR100_12390	ENOG4105C28	cystathionine
KR100_12400	ENOG4105C6T	cysteine synthase
KR100_12430	ENOG4105C59	p-type ATPase
KR100_12470	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
KR100_12485	ENOG4108IQE	Amp-dependent synthetase and ligase
KR100_12490	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
KR100_12500	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
KR100_12505	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
KR100_12515	ENOG4108KMV	Glycosyl transferase (Group 1
KR100_12525	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
KR100_12540	ENOG4107U45	Cobalt transport protein
KR100_12545	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
KR100_12565	ENOG4107QZ7	Cellulose synthase catalytic subunit
KR100_12575	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
KR100_12595	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
KR100_12600	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
KR100_12605	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
KR100_12610	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
KR100_12650	ENOG4105ECX	polysaccharide export
KR100_12675	ENOG4105CQR	helicase
KR100_12690	ENOG4105C09	Bile acid
KR100_12695	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
KR100_12710	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
KR100_12735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
KR100_12740	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
KR100_12750	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
KR100_12785	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KR100_12790	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR100_12795	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR100_12800	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR100_12805	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR100_12815	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
KR100_12820	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
KR100_12825	ENOG4105E66	phosphoriboisomerase A
KR100_12830	ENOG4105C0H	protease
KR100_12865	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
KR100_12870	ENOG4105CHV	Transcription elongation factor NusA
KR100_12890	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
KR100_13000	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
KR100_13005	ENOG4105K70	DNA-binding protein
KR100_13050	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
KR100_13080	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
KR100_13085	ENOG4105CUV	Homoserine Kinase
KR100_13090	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
KR100_13100	ENOG4105WH1	Two component transcriptional regulator luxr family
KR100_13140	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
KR100_13155	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
KR100_13160	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR100_13170	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
KR100_13175	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR100_13185	ENOG4107QPR	SAICAR synthetase
KR100_13220	ENOG4105C12	Phosphoribosylglycinamide synthetase
KR100_13230	ENOG4105EHU	Circadian clock protein KaiC
KR100_13235	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
KR100_13240	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
KR100_13245	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
KR100_13250	ENOG4105K46	50S ribosomal protein l27
KR100_13260	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
KR100_13265	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
KR100_13275	ENOG4105CDY	transcriptional regulatory protein
KR100_13295	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
KR100_13300	ENOG4105JFG	SpoIID LytB domain protein
KR100_13305	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
KR100_13310	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
KR100_13325	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
KR100_13375	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
KR100_13400	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
KR100_13410	ENOG4105DFF	Rod shape-determining protein mreb
KR100_13425	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
KR100_13435	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
KR100_13450	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
KR100_13455	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
KR100_13460	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
KR100_13465	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
KR100_13480	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
KR100_13490	ENOG4105EWV	Sodium calcium exchanger membrane region
KR100_13495	ENOG4107RAQ	aminopeptidase
KR100_13505	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
KR100_13550	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
KR100_13555	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
KR100_13560	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR100_13565	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR100_13570	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR100_13575	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR100_13580	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
KR100_13590	ENOG4107SWE	Methyltransferase
KR100_13595	ENOG4105EEK	Polypeptide
KR100_13635	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
KR100_13640	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
KR100_13665	ENOG4105J3Q	acyl carrier protein
KR100_13680	ENOG4105E12	capsule polysaccharide
KR100_13685	ENOG4105F0R	Cytidylyltransferase
KR100_13700	ENOG4105D2T	synthase
KR100_13870	ENOG4105EEQ	Na H antiporter
KR100_13965	ENOG410851E	CsbD-like
KR100_13980	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
KR100_13995	ENOG4105E0X	reductase
KR100_14010	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
KR100_14020	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
KR100_14050	ENOG4107YU2	histidine triad (hIT) protein
KR100_14055	ENOG4105C0P	Mg chelatase subunit ChlI
KR100_14085	ENOG4105C0P	Mg chelatase subunit ChlI
KR100_14100	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
KR100_14110	ENOG41084W5	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
KR100_14155	ENOG4106BTU	phycobilisome rod-core linker polypeptide
KR100_14205	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
KR100_14215	ENOG4105BZS	acriflavin resistance protein
KR100_14225	ENOG4105D1H	recombination factor protein RarA
KR100_14245	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR100_14250	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
KR100_14255	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
KR100_14265	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
KR100_14275	ENOG4105CZN	Potassium uptake protein
KR100_14280	ENOG4107ZYR	domain protein
KR100_14285	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
KR100_14310	ENOG4105C5H	ABC transporter
KR100_14320	ENOG4105C0H	protease
KR100_14340	ENOG4105CQ7	ATP-dependent helicase
KR100_14345	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR100_14355	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
KR100_14360	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
KR100_14405	ENOG4105ECY	inositol monophosphatase
KR100_14420	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
KR100_14430	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
KR100_14435	ENOG4108IYU	L-aspartate oxidase
KR100_14440	ENOG4105CVB	Vitamin K epoxide reductase
KR100_14445	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
KR100_14465	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
KR100_14510	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
KR100_14540	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
KR100_14545	ENOG4105QE3	oxidoreductase
KR100_14570	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
KR100_14575	ENOG4105D17	glycoside hydrolase, family 3 domain protein
KR100_14580	ENOG4107TVC	Glycosyl transferase, family 2
KR100_14585	ENOG4108DIF	synthase (EC 4.2.1.75)
KR100_14605	ENOG4105CVN	desaturase
KR100_14620	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR100_14635	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
KR100_14640	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR100_14650	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
KR100_14665	ENOG4108PWY	Carbohydrate-selective porin OprB
KR100_14670	ENOG4108PWY	Carbohydrate-selective porin OprB
KR100_14705	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
KR100_14710	ENOG4105VUV	UPF0367 protein
KR100_14715	ENOG4108JJB	ABC transporter
KR100_14725	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
KR100_14730	ENOG4107QRG	dna polymerase iii
KR100_14735	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
KR100_14740	ENOG4105C59	p-type ATPase
KR100_14745	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
KR100_14770	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
KR100_14775	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
KR100_14795	ENOG41072GX	Peptidase M22 Glycoprotease
KR100_14805	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KR100_14810	ENOG4105VFU	Rna-binding protein
KR100_14815	ENOG4105FE1	phytoene synthase
KR100_14820	ENOG4105CVN	desaturase
KR100_14825	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR100_14835	ENOG4105DUM	transcriptional regulator, lysR family
KR100_14845	ENOG4105D65	subunit l
KR100_14850	ENOG4105C8S	subunit m
KR100_14880	ENOG41080ZE	Adenylate cyclase
KR100_14885	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
KR100_14890	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR100_14900	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR100_14905	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
KR100_14915	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
KR100_14930	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
KR100_14935	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
KR100_14950	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
KR100_14985	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
KR100_14995	ENOG4105C3J	Cysteine desulfurase
KR100_15010	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
KR100_15015	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR100_15020	ENOG4105K64	Glycosyl transferase, family 2
KR100_15030	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
KR100_15035	ENOG4105CEY	Amp-dependent synthetase and ligase
KR100_15060	ENOG4105D7Z	glutathione synthase
KR100_15070	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
KR100_15080	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
KR100_15090	ENOG4105DDQ	anthranilate synthase
KR100_15100	ENOG4107RB3	L-asparaginase
KR100_15105	ENOG4105CIH	Imidazole acetol-phosphate transaminase
KR100_15110	ENOG4105C75	arginyL-tRNA synthetase
KR100_15125	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
KR100_15140	ENOG4108JQ6	ABC transporter
KR100_15170	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
KR100_15180	ENOG4105BZA	Phosphoglycerate kinase
KR100_15200	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
KR100_15215	ENOG4105GVR	general secretion pathway protein D
KR100_15235	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
KR100_15240	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
KR100_15250	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
KR100_15255	ENOG4107Z3D	50S ribosomal protein l10
KR100_15260	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
KR100_15265	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
KR100_15280	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
KR100_15290	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
KR100_15335	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
KR100_15340	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
KR100_15345	ENOG4105C9Q	fumarate hydratase class II
KR100_15355	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
KR100_15395	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
KR100_15400	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
KR100_15405	ENOG4105F8J	Adenylate Guanylate cyclase
KR100_15430	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
KR100_15440	ENOG4105C0D	helicase
KR100_15470	ENOG4105K3M	)-transporter
KR100_15510	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KR100_15515	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
KR100_15520	ENOG4105CXI	aluminum resistance protein
KR100_15530	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
KR100_15535	ENOG4105CDU	Replicative dna helicase
KR100_15535	ENOG4105CDU	Replicative dna helicase
KR100_15610	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)