locus-tag	class	description
KR100_00040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KR100_00060	COG0398	Pfam SNARE associated Golgi protein
KR100_00075	COG1131	(ABC) transporter
KR100_00085	COG0525	valine-tRNA ligase activity
KR100_00115	COG1028	Short-chain dehydrogenase reductase Sdr
KR100_00245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KR100_00250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KR100_00300	COG3956	TIGRFAM MazG family protein
KR100_00310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KR100_00315	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KR100_00320	COG0010	Belongs to the arginase family
KR100_00335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KR100_00345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KR100_00350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR100_00355	COG0504	CTP synthase activity
KR100_00360	COG0602	queuosine metabolic process
KR100_00365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR100_00375	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KR100_00380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KR100_00395	COG0366	Alpha amylase catalytic
KR100_00400	COG0463	Glycosyl transferase, family 2
KR100_00430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR100_00445	COG0410	ABC transporter
KR100_00450	COG0411	ABC transporter
KR100_00470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KR100_00475	COG0830	nickel cation binding
KR100_00480	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KR100_00485	COG0829	nickel cation binding
KR100_00490	COG0831	urea catabolic process
KR100_00495	COG0832	Belongs to the urease beta subunit family
KR100_00500	COG0804	urea catabolic process
KR100_00510	COG2308	Evidence 4 Homologs of previously reported genes of
KR100_00540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KR100_00545	COG0746	molybdenum cofactor guanylyltransferase activity
KR100_00550	COG2223	nitrite transmembrane transporter activity
KR100_00555	COG0243	molybdopterin cofactor binding
KR100_00575	COG0315	cyclic pyranopterin monophosphate synthase activity
KR100_00590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KR100_00595	COG0314	molybdopterin synthase activity
KR100_00605	COG0521	Mo-molybdopterin cofactor biosynthetic process
KR100_00610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KR100_00620	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KR100_00635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KR100_00650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KR100_00655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR100_00675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KR100_00680	COG1049	propionate catabolic process, 2-methylcitrate cycle
KR100_00700	COG0788	formyltetrahydrofolate deformylase activity
KR100_00720	COG0443	Heat shock 70 kDa protein
KR100_00725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KR100_00735	COG0360	Binds together with S18 to 16S ribosomal RNA
KR100_00745	COG0137	argininosuccinate synthase activity
KR100_00760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KR100_00780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KR100_00785	COG0438	transferase activity, transferring glycosyl groups
KR100_00795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KR100_00800	COG0497	DNA recombination
KR100_00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KR100_00815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KR100_00820	COG0592	DNA-directed DNA polymerase activity
KR100_00830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KR100_00835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KR100_00840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KR100_00850	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KR100_00870	COG0552	protein localization to endoplasmic reticulum
KR100_00875	COG2208	phosphoserine phosphatase activity
KR100_00880	COG0165	Argininosuccinate lyase
KR100_00885	COG0724	RNA recognition motif
KR100_00890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KR100_00895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KR100_00900	COG2081	HI0933 family
KR100_00920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KR100_00925	COG0484	heat shock protein binding
KR100_00935	COG1162	GTPase activity
KR100_00940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KR100_00945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KR100_00950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KR100_00955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KR100_00960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KR100_00965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KR100_00970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KR100_00975	COG0511	ligase activity, forming carbon-carbon bonds
KR100_00980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KR100_01050	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KR100_01055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KR100_01055	COG0519	Catalyzes the synthesis of GMP from XMP
KR100_01070	COG0768	penicillin binding
KR100_01075	COG0438	transferase activity, transferring glycosyl groups
KR100_01080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KR100_01090	COG2022	thiamine diphosphate biosynthetic process
KR100_01105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KR100_01110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KR100_01115	COG2385	sporulation resulting in formation of a cellular spore
KR100_01120	COG1215	transferase activity, transferring glycosyl groups
KR100_01125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KR100_01135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KR100_01140	COG0740	serine-type endopeptidase activity
KR100_01145	COG0544	peptidyl-prolyl cis-trans isomerase activity
KR100_01150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KR100_01155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KR100_01160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KR100_01200	COG2082	Precorrin-8x methylmutase
KR100_01205	COG0037	tRNA processing
KR100_01225	COG0556	nucleotide-excision repair
KR100_01230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KR100_01240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KR100_01315	COG1086	Polysaccharide biosynthesis protein
KR100_01340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KR100_01385	COG3958	Transketolase
KR100_01390	COG3959	Transketolase, thiamine diphosphate binding domain
KR100_01405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KR100_01405	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KR100_01415	COG0469	pyruvate kinase activity
KR100_01450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KR100_01485	COG0438	transferase activity, transferring glycosyl groups
KR100_01500	COG0438	transferase activity, transferring glycosyl groups
KR100_01575	COG0653	protein targeting
KR100_01600	COG1045	serine acetyltransferase
KR100_01605	COG1725	Transcriptional regulator
KR100_01610	COG0412	Dienelactone hydrolase
KR100_01615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KR100_01620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KR100_01625	COG1372	Participates in initiation and elongation during chromosome replication
KR100_01625	COG0187	DNA topoisomerase II activity
KR100_01635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KR100_01640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KR100_01645	COG0386	Belongs to the glutathione peroxidase family
KR100_01650	COG2239	Acts as a magnesium transporter
KR100_01655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR100_01685	COG0714	Associated with various cellular activities
KR100_01705	COG1194	a g-specific adenine glycosylase
KR100_01715	COG0802	atpase or kinase
KR100_01720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KR100_01725	COG0586	Pfam SNARE associated Golgi protein
KR100_01730	COG0629	single-stranded DNA binding
KR100_01760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KR100_01780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KR100_01785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KR100_01790	COG0515	serine threonine protein kinase
KR100_01790	COG1357	PFAM Pentapeptide repeats (8 copies)
KR100_01800	COG2255	four-way junction helicase activity
KR100_01810	COG1473	amidohydrolase
KR100_01825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KR100_01830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KR100_01835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KR100_01840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KR100_01845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_01850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KR100_01855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KR100_01860	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KR100_01865	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KR100_01865	COG0662	Cupin 2, conserved barrel domain protein
KR100_01870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KR100_01880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR100_01885	COG0571	ribonuclease III activity
KR100_01905	COG0582	viral genome integration into host DNA
KR100_02055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KR100_02060	COG0058	SHG alpha-glucan phosphorylase activity
KR100_02065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KR100_02075	COG0475	glutathione-regulated potassium exporter activity
KR100_02095	COG0277	FAD linked oxidase domain protein
KR100_02105	COG0247	lactate metabolic process
KR100_02115	COG0538	isocitrate dehydrogenase activity
KR100_02125	COG0538	isocitrate dehydrogenase activity
KR100_02130	COG0463	Glycosyl transferase, family 2
KR100_02140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KR100_02150	COG5398	heme oxygenase
KR100_02165	COG0438	transferase activity, transferring glycosyl groups
KR100_02170	COG0438	transferase activity, transferring glycosyl groups
KR100_02175	COG0438	transferase activity, transferring glycosyl groups
KR100_02205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KR100_02220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KR100_02225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KR100_02230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KR100_02230	COG0517	IMP dehydrogenase activity
KR100_02235	COG0617	tRNA 3'-terminal CCA addition
KR100_02245	COG0709	Synthesizes selenophosphate from selenide and ATP
KR100_02250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KR100_02260	COG2274	protein secretion by the type I secretion system
KR100_02275	COG0438	transferase activity, transferring glycosyl groups
KR100_02280	COG0124	histidyl-tRNA synthetase
KR100_02290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KR100_02320	COG4447	cellulose binding
KR100_02330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_02335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_02340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_02345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KR100_02350	COG3842	ATPase activity
KR100_02360	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KR100_02360	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KR100_02370	COG0494	nUDIX hydrolase
KR100_02375	COG0415	Belongs to the DNA photolyase family
KR100_02420	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KR100_02425	COG3781	membrane
KR100_02430	COG0131	Imidazoleglycerol-phosphate dehydratase
KR100_02435	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
KR100_02455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KR100_02465	COG0039	L-malate dehydrogenase activity
KR100_02475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KR100_02490	COG0354	folic acid binding
KR100_02495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KR100_02505	COG1253	flavin adenine dinucleotide binding
KR100_02510	COG0673	inositol 2-dehydrogenase activity
KR100_02530	COG0343	queuine tRNA-ribosyltransferase activity
KR100_02545	COG2205	protein histidine kinase activity
KR100_02560	COG0138	bifunctional purine biosynthesis protein purh
KR100_02575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KR100_02580	COG0004	ammonium transporteR
KR100_02585	COG1489	DNA binding
KR100_02590	COG0728	peptidoglycan biosynthetic process
KR100_02620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KR100_02625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KR100_02630	COG1058	Belongs to the CinA family
KR100_02630	COG1546	Belongs to the CinA family
KR100_02635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KR100_02640	COG0066	3-isopropylmalate dehydratase activity
KR100_02675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KR100_02680	COG0193	aminoacyl-tRNA hydrolase activity
KR100_02695	COG4372	Transposase
KR100_02705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KR100_02725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KR100_02745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KR100_02750	COG2971	BadF BadG BcrA BcrD
KR100_02760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KR100_02780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KR100_02805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KR100_02820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KR100_02825	COG2094	Belongs to the DNA glycosylase MPG family
KR100_02830	COG0540	Belongs to the ATCase OTCase family
KR100_02860	COG3536	Protein conserved in bacteria
KR100_02865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KR100_02875	COG2046	Belongs to the sulfate adenylyltransferase family
KR100_02875	COG0529	Catalyzes the synthesis of activated sulfate
KR100_02880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR100_02885	COG0800	Aldolase
KR100_02895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KR100_02930	COG0725	ABC transporter, periplasmic molybdate-binding protein
KR100_02935	COG4149	molybdate abc transporter
KR100_02940	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KR100_02960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KR100_02965	COG0436	Aminotransferase
KR100_02975	COG1530	ribonuclease E activity
KR100_02980	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KR100_02990	COG1605	Chorismate mutase
KR100_02990	COG0077	Prephenate dehydratase
KR100_02995	COG2226	methyltransferase
KR100_03005	COG0051	transcription antitermination factor activity, RNA binding
KR100_03010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KR100_03015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KR100_03020	COG0049	tRNA binding
KR100_03025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KR100_03040	COG0069	glutamate synthase activity
KR100_03040	COG0067	glutamate synthase
KR100_03040	COG0070	glutamate synthase
KR100_03050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KR100_03060	COG3659	wide pore channel activity
KR100_03085	COG0492	ferredoxin-NADP+ reductase activity
KR100_03100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR100_03105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KR100_03115	COG1840	ABC-type Fe3 transport system, periplasmic component
KR100_03125	COG3659	wide pore channel activity
KR100_03150	COG2885	chlorophyll binding
KR100_03155	COG2885	chlorophyll binding
KR100_03200	COG0463	Glycosyl transferase, family 2
KR100_03220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR100_03230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KR100_03240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KR100_03245	COG0254	rRNA binding
KR100_03250	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KR100_03255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KR100_03260	COG0101	tRNA pseudouridine synthase activity
KR100_03265	COG0203	ribosomal protein L17
KR100_03270	COG0202	RNA polymerase activity
KR100_03275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KR100_03280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KR100_03290	COG0563	adenylate kinase activity
KR100_03295	COG0201	protein transport
KR100_03300	COG0200	Binds to the 23S rRNA
KR100_03305	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KR100_03310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KR100_03315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KR100_03320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KR100_03325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KR100_03330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KR100_03335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KR100_03340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KR100_03345	COG0255	Belongs to the universal ribosomal protein uL29 family
KR100_03350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KR100_03355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KR100_03360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KR100_03365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KR100_03370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KR100_03375	COG0089	rRNA binding
KR100_03380	COG0088	Forms part of the polypeptide exit tunnel
KR100_03385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KR100_03400	COG3854	ATPases associated with a variety of cellular activities
KR100_03415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KR100_03435	COG0287	Prephenate dehydrogenase
KR100_03440	COG1233	COG1233 Phytoene dehydrogenase and related
KR100_03465	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KR100_03470	COG1606	tRNA processing
KR100_03475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KR100_03480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KR100_03495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KR100_03500	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KR100_03505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KR100_03520	COG0772	Belongs to the SEDS family
KR100_03525	COG0489	protein tyrosine kinase activity
KR100_03530	COG0408	coproporphyrinogen oxidase activity
KR100_03550	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KR100_03585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KR100_03590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KR100_03595	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KR100_03595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KR100_03600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KR100_03605	COG1413	lyase activity
KR100_03755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KR100_03810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KR100_03820	COG0539	negative regulation of cytoplasmic translation
KR100_03825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KR100_03855	COG0824	Thioesterase
KR100_03860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KR100_03860	COG0758	DNA mediated transformation
KR100_03865	COG2890	protein-(glutamine-N5) methyltransferase activity
KR100_03870	COG0009	L-threonylcarbamoyladenylate synthase
KR100_03890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KR100_03895	COG2894	cell division
KR100_03900	COG0850	regulation of cytokinetic process
KR100_03905	COG1078	dGTPase activity
KR100_03910	COG0793	Belongs to the peptidase S41A family
KR100_03915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KR100_03920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KR100_03930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KR100_03950	COG1388	LysM domain
KR100_03950	COG3942	CHAP domain
KR100_03955	COG1012	belongs to the aldehyde dehydrogenase family
KR100_03965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KR100_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KR100_03990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KR100_04060	COG0659	secondary active sulfate transmembrane transporter activity
KR100_04065	COG4243	Vitamin k epoxide reductase
KR100_04070	COG0484	heat shock protein binding
KR100_04075	COG0113	porphobilinogen synthase activity
KR100_04085	COG1193	negative regulation of DNA recombination
KR100_04100	COG3842	ATPase activity
KR100_04105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KR100_04120	COG0488	(ABC) transporter
KR100_04130	COG0435	Glutathione S-transferase
KR100_04135	COG2988	succinylglutamate desuccinylase activity
KR100_04415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KR100_04430	COG1218	3'(2'),5'-bisphosphate nucleotidase
KR100_04435	COG1185	polyribonucleotide nucleotidyltransferase activity
KR100_04440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KR100_04445	COG0750	zinc metalloprotease
KR100_04450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KR100_04470	COG0706	membrane insertase activity
KR100_04480	COG0594	ribonuclease P activity
KR100_04495	COG0616	signal peptide processing
KR100_04500	COG0697	spore germination
KR100_04510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KR100_04525	COG1842	Phage shock protein A
KR100_04530	COG3118	belongs to the thioredoxin family
KR100_04535	COG0436	Aminotransferase
KR100_04540	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KR100_04540	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KR100_04545	COG0739	heme binding
KR100_04550	COG0745	RESPONSE REGULATOR receiver
KR100_04560	COG5002	protein histidine kinase activity
KR100_04570	COG0577	efflux transmembrane transporter activity
KR100_04570	COG1136	(ABC) transporter
KR100_04575	COG1007	ATP synthesis coupled electron transport
KR100_04580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KR100_04595	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KR100_04625	COG1845	cytochrome c oxidase, subunit III
KR100_04630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KR100_04640	COG1612	heme a metabolic process
KR100_04645	COG0109	protoheme IX farnesyltransferase activity
KR100_04665	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KR100_04670	COG0459	protein refolding
KR100_04680	COG1028	Short-chain dehydrogenase reductase Sdr
KR100_04695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KR100_04700	COG1619	proteins homologs of microcin C7 resistance protein MccF
KR100_04705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KR100_04710	COG0248	Ppx GppA phosphatase
KR100_04725	COG2875	Belongs to the precorrin methyltransferase family
KR100_04730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KR100_04735	COG0739	heme binding
KR100_04740	COG0723	plastoquinol--plastocyanin reductase activity
KR100_04750	COG0805	protein transport
KR100_04760	COG0194	GDP metabolic process
KR100_04775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KR100_04795	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KR100_04815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KR100_04835	COG0335	large ribosomal subunit rRNA binding
KR100_04845	COG0024	Methionine aminopeptidase
KR100_04850	COG0300	oxidoreductase activity
KR100_04850	COG3000	fatty acid hydroxylase
KR100_04860	COG0857	belongs to the CobB CobQ family
KR100_04895	COG1666	GTP binding
KR100_04935	COG0295	cytidine deaminase activity
KR100_04945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KR100_04950	COG0277	FAD linked oxidase domain protein
KR100_04955	COG0708	Exodeoxyribonuclease III
KR100_04975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR100_04980	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KR100_05025	COG0523	cobalamin synthesis protein
KR100_05030	COG2154	pterin-4-alpha-carbinolamine dehydratase
KR100_05035	COG0432	Pfam Uncharacterised protein family UPF0047
KR100_05050	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KR100_05055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KR100_05070	COG0181	hydroxymethylbilane synthase activity
KR100_05115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR100_05130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KR100_05140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KR100_05155	COG0629	single-stranded DNA binding
KR100_05170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KR100_05175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KR100_05185	COG0442	prolyl-tRNA aminoacylation
KR100_05200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KR100_05230	COG0406	alpha-ribazole phosphatase activity
KR100_05245	COG0768	penicillin binding
KR100_05250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KR100_05260	COG2211	Major facilitator Superfamily
KR100_05270	COG0415	Belongs to the DNA photolyase family
KR100_05280	COG0233	cytoplasmic translational termination
KR100_05285	COG0528	UMP kinase activity
KR100_05300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR100_05310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KR100_05315	COG0028	Belongs to the TPP enzyme family
KR100_05340	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KR100_05355	COG0539	negative regulation of cytoplasmic translation
KR100_05365	COG3396	Phenylacetate-CoA oxygenase
KR100_05370	COG5322	oxidoreductase activity
KR100_05375	COG0825	malonyl-CoA metabolic process
KR100_05380	COG4221	oxidoreductase activity
KR100_05390	COG0135	phosphoribosylanthranilate isomerase activity
KR100_05395	COG0517	IMP dehydrogenase activity
KR100_05395	COG1994	Peptidase M50
KR100_05400	COG0095	Lipoate-protein ligase
KR100_05405	COG0730	response to heat
KR100_05430	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KR100_05435	COG1231	oxidoreductase activity
KR100_05440	COG2249	NAD(P)H dehydrogenase (quinone) activity
KR100_05445	COG1231	oxidoreductase activity
KR100_05450	COG1231	oxidoreductase activity
KR100_05455	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KR100_05460	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KR100_05485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KR100_05495	COG1850	ribulose-bisphosphate carboxylase activity
KR100_05500	COG4451	ribulose bisphosphate carboxylase, small
KR100_05530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KR100_05535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_05575	COG1492	cobalamin metabolic process
KR100_05590	COG0424	maF-like protein
KR100_05600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KR100_05605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KR100_05615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KR100_05620	COG0668	transmembrane transport
KR100_05625	COG0215	cysteine-tRNA ligase activity
KR100_05635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KR100_05635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KR100_05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KR100_05645	COG0012	GTP binding
KR100_05675	COG4166	transmembrane transport
KR100_05685	COG0460	homoserine dehydrogenase
KR100_05690	COG2166	iron-sulfur cluster assembly
KR100_05700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KR100_05705	COG2226	methyltransferase
KR100_05780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KR100_05785	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KR100_05800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KR100_05805	COG2010	Cytochrome c
KR100_05810	COG0742	ribosomal rna small subunit methyltransferase
KR100_05815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KR100_05820	COG3118	belongs to the thioredoxin family
KR100_05825	COG0516	GMP reductase activity
KR100_05830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KR100_05835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KR100_05840	COG0644	oxidoreductase
KR100_05845	COG1543	Belongs to the glycosyl hydrolase 57 family
KR100_05850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KR100_05855	COG0395	ABC-type sugar transport system, permease component
KR100_05875	COG0011	TIGRFAM Protein of
KR100_05890	COG1480	7TM receptor with intracellular HD hydrolase
KR100_05895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KR100_05935	COG0406	alpha-ribazole phosphatase activity
KR100_05950	COG1254	Belongs to the acylphosphatase family
KR100_05955	COG1797	cobyrinic acid a,c-diamide synthase activity
KR100_05965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KR100_05970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KR100_05985	COG2205	protein histidine kinase activity
KR100_06005	COG0308	aminopeptidase N
KR100_06050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KR100_06060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR100_06085	COG1376	ErfK ybiS ycfS ynhG family protein
KR100_06100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KR100_06155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KR100_06165	COG2197	response regulator
KR100_06170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KR100_06185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KR100_06200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KR100_06205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KR100_06210	COG0473	3-isopropylmalate dehydrogenase activity
KR100_06215	COG3954	Phosphoribulokinase
KR100_06225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KR100_06230	COG0515	serine threonine protein kinase
KR100_06235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KR100_06245	COG1528	Iron-storage protein
KR100_06250	COG3659	wide pore channel activity
KR100_06255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KR100_06265	COG0673	inositol 2-dehydrogenase activity
KR100_06270	COG3588	fructose-bisphosphate aldolase
KR100_06275	COG0191	fructose-bisphosphate aldolase activity
KR100_06280	COG1619	proteins homologs of microcin C7 resistance protein MccF
KR100_06285	COG0047	phosphoribosylformylglycinamidine synthase activity
KR100_06290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KR100_06305	COG0668	transmembrane transport
KR100_06315	COG0640	Transcriptional regulator
KR100_06345	COG2205	protein histidine kinase activity
KR100_06375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR100_06380	COG0716	FMN binding
KR100_06410	COG0745	RESPONSE REGULATOR receiver
KR100_06440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KR100_06450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR100_06455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KR100_06465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KR100_06470	COG1429	ligase activity, forming nitrogen-metal bonds
KR100_06480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KR100_06485	COG0149	triose-phosphate isomerase activity
KR100_06495	COG1132	(ABC) transporter
KR100_06505	COG1115	amino acid carrier protein
KR100_06515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KR100_06525	COG0799	negative regulation of ribosome biogenesis
KR100_06545	COG0515	serine threonine protein kinase
KR100_06570	COG0659	secondary active sulfate transmembrane transporter activity
KR100_06585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KR100_06590	COG4597	amino acid ABC transporter
KR100_06595	COG0765	amino acid transport
KR100_06600	COG1126	abc transporter atp-binding protein
KR100_06725	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KR100_06730	COG2873	o-acetylhomoserine
KR100_06845	COG0625	glutathione transferase activity
KR100_06895	COG1799	cell septum assembly
KR100_06910	COG0735	belongs to the Fur family
KR100_06915	COG2197	response regulator
KR100_06925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KR100_06975	COG0123	including yeast histone deacetylase and acetoin utilization protein
KR100_07240	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KR100_07255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KR100_07265	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KR100_07270	COG1233	COG1233 Phytoene dehydrogenase and related
KR100_07290	COG0745	RESPONSE REGULATOR receiver
KR100_07300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KR100_07305	COG0271	Belongs to the BolA IbaG family
KR100_07320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KR100_07340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KR100_07345	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KR100_07355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KR100_07365	COG0513	Belongs to the DEAD box helicase family
KR100_07380	COG0724	RNA recognition motif
KR100_07390	COG1132	(ABC) transporter
KR100_07395	COG0589	response to stress
KR100_07395	COG0475	glutathione-regulated potassium exporter activity
KR100_07415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KR100_07435	COG2197	response regulator
KR100_07440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KR100_07490	COG3420	alginic acid biosynthetic process
KR100_07495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KR100_07500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KR100_07505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KR100_07510	COG0019	diaminopimelate decarboxylase activity
KR100_07520	COG0542	response to heat
KR100_07525	COG0371	Dehydrogenase
KR100_07530	COG0596	Alpha beta hydrolase
KR100_07540	COG0575	Belongs to the CDS family
KR100_07555	COG3220	belongs to the UPF0276 family
KR100_07560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KR100_07565	COG1982	Orn Lys Arg decarboxylase major
KR100_07575	COG2274	protein secretion by the type I secretion system
KR100_07595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KR100_07615	COG0745	RESPONSE REGULATOR receiver
KR100_07620	COG5002	protein histidine kinase activity
KR100_07625	COG1187	pseudouridine synthase activity
KR100_07635	COG1640	4-alpha-glucanotransferase
KR100_07655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KR100_07715	COG1121	(ABC) transporter
KR100_07740	COG0701	Predicted permease
KR100_07765	COG0367	asparagine synthase
KR100_07770	COG0540	Belongs to the ATCase OTCase family
KR100_07790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KR100_07840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KR100_07840	COG0116	Belongs to the methyltransferase superfamily
KR100_07845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KR100_07920	COG0681	Belongs to the peptidase S26 family
KR100_07930	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KR100_07935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KR100_07940	COG1376	ErfK ybiS ycfS ynhG family protein
KR100_07945	COG0297	glycogen (starch) synthase activity
KR100_07955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KR100_07965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KR100_08015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KR100_08020	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KR100_08025	COG2045	Belongs to the ComB family
KR100_08030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR100_08035	COG0860	N-Acetylmuramoyl-L-alanine amidase
KR100_08040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KR100_08045	COG0142	geranyltranstransferase activity
KR100_08050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR100_08060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KR100_08070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR100_08075	COG2176	DNA-directed DNA polymerase activity
KR100_08090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KR100_08110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KR100_08120	COG1132	(ABC) transporter
KR100_08130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KR100_08135	COG0505	Belongs to the CarA family
KR100_08145	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KR100_08155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR100_08165	COG0154	amidase activity
KR100_08170	COG0587	DNA-directed DNA polymerase activity
KR100_08180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KR100_08185	COG1006	Multisubunit Na H antiporter MnhC subunit
KR100_08210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KR100_08215	COG1809	phosphosulfolactate synthase activity
KR100_08220	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KR100_08230	COG0632	four-way junction helicase activity
KR100_08245	COG0358	DNA primase activity
KR100_08300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KR100_08310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KR100_08360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KR100_08385	COG0740	serine-type endopeptidase activity
KR100_08390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR100_08395	COG1136	(ABC) transporter
KR100_08395	COG0577	efflux transmembrane transporter activity
KR100_08400	COG0469	pyruvate kinase activity
KR100_08440	COG0861	Integral membrane protein TerC family
KR100_08455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KR100_08470	COG0312	modulator of DNA gyrase
KR100_08475	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KR100_08490	COG0163	prenyltransferase activity
KR100_08495	COG0557	exoribonuclease II activity
KR100_08505	COG2119	membrane
KR100_08520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KR100_08520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KR100_08525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KR100_08540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KR100_08545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR100_08550	COG1615	UPF0182 protein
KR100_08555	COG0450	alkyl hydroperoxide reductase
KR100_08570	COG0739	heme binding
KR100_08575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KR100_08620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KR100_08635	COG0557	exoribonuclease II activity
KR100_08640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KR100_08645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KR100_08650	COG0072	phenylalanine-tRNA ligase activity
KR100_08650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KR100_08655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KR100_08680	COG1191	sigma factor activity
KR100_08690	COG2385	sporulation resulting in formation of a cellular spore
KR100_08715	COG0646	methionine synthase
KR100_08715	COG1410	methionine synthase
KR100_08720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KR100_08735	COG0613	PHP domain protein
KR100_08745	COG3046	protein related to deoxyribodipyrimidine photolyase
KR100_08755	COG0322	excinuclease ABC activity
KR100_08765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KR100_08790	COG1104	cysteine desulfurase activity
KR100_08795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KR100_08825	COG0495	leucyl-tRNA aminoacylation
KR100_08835	COG0166	Belongs to the GPI family
KR100_08890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KR100_08895	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KR100_08900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KR100_08900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KR100_08905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KR100_08910	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KR100_08915	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KR100_08930	COG0484	heat shock protein binding
KR100_08935	COG0443	Heat shock 70 kDa protein
KR100_08940	COG0573	inorganic phosphate transmembrane transporter activity
KR100_08945	COG0581	inorganic phosphate transmembrane transporter activity
KR100_08950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KR100_08960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR100_08965	COG0483	inositol monophosphate 1-phosphatase activity
KR100_08970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KR100_08980	COG0326	Molecular chaperone. Has ATPase activity
KR100_08985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KR100_08990	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR100_08995	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KR100_09000	COG1653	transport
KR100_09040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KR100_09045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KR100_09070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KR100_09095	COG0793	Belongs to the peptidase S41A family
KR100_09100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KR100_09105	COG1573	uracil-dna glycosylase
KR100_09115	COG0436	Aminotransferase
KR100_09120	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KR100_09125	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KR100_09145	COG1836	PFAM Integral membrane protein DUF92
KR100_09165	COG1122	ATPase activity
KR100_09170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KR100_09190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KR100_09195	COG4106	trans-aconitate 2-methyltransferase activity
KR100_09200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KR100_09345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KR100_09355	COG0129	dihydroxy-acid dehydratase activity
KR100_09385	COG0375	protein maturation
KR100_09390	COG0010	Belongs to the arginase family
KR100_09395	COG0363	glucosamine-6-phosphate deaminase activity
KR100_09400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KR100_09405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KR100_09410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KR100_09415	COG1494	fructose-1,6-bisphosphatase
KR100_09420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KR100_09455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KR100_09470	COG1137	ATPase activity
KR100_09490	COG0826	peptidase U32
KR100_09500	COG0644	oxidoreductase
KR100_09510	COG0751	glycine-tRNA ligase activity
KR100_09515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KR100_09520	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KR100_09525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KR100_09535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KR100_09540	COG0052	Belongs to the universal ribosomal protein uS2 family
KR100_09545	COG1216	Glycosyl transferase, family 2
KR100_09565	COG1566	PFAM secretion protein HlyD family protein
KR100_09575	COG0612	Peptidase, M16
KR100_09595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KR100_09600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KR100_09615	COG0590	tRNA wobble adenosine to inosine editing
KR100_09620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KR100_09630	COG0174	glutamine synthetase
KR100_09635	COG2226	methyltransferase
KR100_09660	COG0515	serine threonine protein kinase
KR100_09665	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KR100_09670	COG3310	Protein conserved in bacteria
KR100_09675	COG0628	permease
KR100_09710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KR100_09715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KR100_09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
KR100_09720	COG0022	dehydrogenase e1 component
KR100_09735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KR100_09740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KR100_09815	COG0792	nuclease activity
KR100_09910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KR100_09940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KR100_09970	COG1793	dna ligase
KR100_09980	COG1201	RNA secondary structure unwinding
KR100_10035	COG2059	Chromate
KR100_10065	COG2226	methyltransferase
KR100_10130	COG1120	ATPase activity
KR100_10175	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KR100_10195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KR100_10280	COG1121	(ABC) transporter
KR100_10295	COG0803	Belongs to the bacterial solute-binding protein 9 family
KR100_10300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KR100_10305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR100_10440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KR100_10445	COG1116	anion transmembrane transporter activity
KR100_10450	COG4638	Rieske (2fe-2S)
KR100_10470	COG2144	transferase activity, transferring acyl groups
KR100_10495	COG2072	flavoprotein involved in K transport
KR100_10500	COG0724	RNA recognition motif
KR100_10535	COG2197	response regulator
KR100_10545	COG2234	aminopeptidase activity
KR100_10575	COG0405	Gamma-glutamyltransferase
KR100_10710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KR100_10725	COG2124	cytochrome p450
KR100_10900	COG1230	cation diffusion facilitator family transporter
KR100_10915	COG0180	Tryptophanyl-tRNA synthetase
KR100_10930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KR100_10940	COG0837	glucose binding
KR100_10945	COG0083	homoserine kinase activity
KR100_10950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_10955	COG0339	signal peptide processing
KR100_10965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KR100_10970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KR100_10975	COG1940	carbohydrate kinase activity
KR100_11010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KR100_11015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KR100_11025	COG3794	PFAM blue (type 1) copper domain protein
KR100_11030	COG2010	Cytochrome c
KR100_11050	COG0542	response to heat
KR100_11065	COG0140	phosphoribosyl-ATP diphosphatase activity
KR100_11065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KR100_11080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR100_11130	COG0159	tryptophan synthase activity
KR100_11160	COG0418	dihydroorotase activity
KR100_11165	COG0659	secondary active sulfate transmembrane transporter activity
KR100_11190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KR100_11195	COG1845	cytochrome c oxidase, subunit III
KR100_11230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR100_11250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KR100_11255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR100_11275	COG1132	(ABC) transporter
KR100_11280	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KR100_11285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KR100_11290	COG3842	ATPase activity
KR100_11295	COG0251	oxidation-reduction process
KR100_11395	COG2066	Belongs to the glutaminase family
KR100_11395	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KR100_11400	COG2066	Belongs to the glutaminase family
KR100_11445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KR100_11460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KR100_11465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KR100_11475	COG2135	peptidase activity
KR100_11485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KR100_11485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KR100_11535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KR100_11560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KR100_11565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KR100_11575	COG0196	riboflavin kinase activity
KR100_11585	COG0352	thiamine-phosphate diphosphorylase activity
KR100_11605	COG1691	(AIR) carboxylase
KR100_11615	COG0336	Belongs to the RNA methyltransferase TrmD family
KR100_11640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KR100_11650	COG3659	wide pore channel activity
KR100_11655	COG0477	Major facilitator Superfamily
KR100_11660	COG0670	Belongs to the BI1 family
KR100_11665	COG1702	phosphate starvation-inducible protein PhoH
KR100_11670	COG0228	four-way junction DNA binding
KR100_11675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KR100_11685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KR100_11690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KR100_11695	COG0482	sulfurtransferase activity
KR100_11700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KR100_11720	COG0681	Belongs to the peptidase S26 family
KR100_11730	COG0134	indole-3-glycerol-phosphate synthase activity
KR100_11735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KR100_11740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR100_11755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KR100_11760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KR100_11770	COG0285	dihydrofolate synthase activity
KR100_11805	COG4948	Mandelate Racemase Muconate Lactonizing
KR100_11810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KR100_11815	COG1181	Belongs to the D-alanine--D-alanine ligase family
KR100_11830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KR100_11850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KR100_11855	COG4956	integral membrane protein (PIN domain superfamily)
KR100_11860	COG0740	serine-type endopeptidase activity
KR100_11865	COG0740	serine-type endopeptidase activity
KR100_11870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KR100_11880	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KR100_11885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KR100_11975	COG2340	Cysteine-rich secretory protein family
KR100_12015	COG0752	glycyl-tRNA synthetase alpha subunit
KR100_12025	COG2226	methyltransferase
KR100_12035	COG0107	imidazoleglycerol-phosphate synthase activity
KR100_12045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KR100_12050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KR100_12055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KR100_12055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KR100_12060	COG3695	enzyme binding
KR100_12070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KR100_12090	COG3850	Histidine kinase
KR100_12090	COG5002	protein histidine kinase activity
KR100_12120	COG0745	RESPONSE REGULATOR receiver
KR100_12185	COG0481	GTPase activity
KR100_12200	COG0579	oxidoreductase
KR100_12205	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KR100_12245	COG0733	neurotransmitter:sodium symporter activity
KR100_12250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KR100_12255	COG3411	Ferredoxin
KR100_12265	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KR100_12275	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KR100_12300	COG0492	ferredoxin-NADP+ reductase activity
KR100_12305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KR100_12330	COG2226	methyltransferase
KR100_12355	COG1073	alpha beta
KR100_12360	COG0440	acetolactate synthase activity
KR100_12365	COG2340	Cysteine-rich secretory protein family
KR100_12370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KR100_12390	COG0626	cystathionine gamma-synthase activity
KR100_12400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KR100_12415	COG2119	membrane
KR100_12420	COG2217	Heavy metal translocating P-type atpase
KR100_12430	COG2608	mercury ion transmembrane transporter activity
KR100_12430	COG2217	Heavy metal translocating P-type atpase
KR100_12470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KR100_12485	COG1022	Amp-dependent synthetase and ligase
KR100_12490	COG0321	lipoyl(octanoyl) transferase activity
KR100_12495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KR100_12500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KR100_12505	COG1381	Involved in DNA repair and RecF pathway recombination
KR100_12515	COG0438	transferase activity, transferring glycosyl groups
KR100_12520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KR100_12525	COG1799	cell septum assembly
KR100_12530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KR100_12540	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KR100_12545	COG1160	GTP binding
KR100_12560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KR100_12575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KR100_12610	COG1088	dTDP-glucose 4,6-dehydratase activity
KR100_12645	COG1216	Glycosyl transferase, family 2
KR100_12645	COG0438	transferase activity, transferring glycosyl groups
KR100_12675	COG4581	dead DEAH box helicase
KR100_12690	COG0385	Bile acid
KR100_12695	COG0156	8-amino-7-oxononanoate synthase activity
KR100_12710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KR100_12735	COG0484	heat shock protein binding
KR100_12740	COG0357	Ribosomal RNA small subunit methyltransferase G
KR100_12785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KR100_12795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KR100_12800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KR100_12805	COG0085	RNA polymerase activity
KR100_12810	COG0084	hydrolase, TatD family'
KR100_12815	COG0268	Binds directly to 16S ribosomal RNA
KR100_12820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KR100_12825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KR100_12830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR100_12855	COG0641	radical SAM
KR100_12865	COG0779	Required for maturation of 30S ribosomal subunits
KR100_12870	COG0195	Participates in both transcription termination and antitermination
KR100_12890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KR100_12925	COG1053	succinate dehydrogenase
KR100_12960	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KR100_13000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KR100_13005	COG0776	regulation of translation
KR100_13025	COG2211	Major facilitator Superfamily
KR100_13030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KR100_13050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KR100_13080	COG0284	orotidine-5'-phosphate decarboxylase activity
KR100_13085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KR100_13090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KR100_13100	COG2197	response regulator
KR100_13140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KR100_13155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KR100_13160	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KR100_13165	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KR100_13170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KR100_13175	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KR100_13185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KR100_13220	COG0151	Belongs to the GarS family
KR100_13225	COG5002	protein histidine kinase activity
KR100_13230	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KR100_13235	COG4251	negative regulation of phosphorylation
KR100_13245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KR100_13250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KR100_13260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR100_13265	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KR100_13275	COG0217	transcriptional regulatory protein
KR100_13295	COG0363	glucosamine-6-phosphate deaminase activity
KR100_13300	COG2385	sporulation resulting in formation of a cellular spore
KR100_13300	COG2247	cell wall binding repeat
KR100_13305	COG1234	tRNA 3'-trailer cleavage
KR100_13310	COG2010	Cytochrome c
KR100_13325	COG2264	protein methyltransferase activity
KR100_13330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KR100_13375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KR100_13410	COG1077	Cell shape determining protein MreB Mrl
KR100_13425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KR100_13435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KR100_13450	COG0459	protein refolding
KR100_13455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KR100_13460	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KR100_13465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KR100_13490	COG0387	Pfam Sodium calcium exchanger
KR100_13495	COG0006	proline dipeptidase activity
KR100_13500	COG1253	flavin adenine dinucleotide binding
KR100_13515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KR100_13515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR100_13525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KR100_13535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KR100_13550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KR100_13555	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KR100_13560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KR100_13565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KR100_13575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KR100_13580	COG0356	it plays a direct role in the translocation of protons across the membrane
KR100_13590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR100_13595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KR100_13625	COG0772	Belongs to the SEDS family
KR100_13635	COG1333	cytochrome c biogenesis protein
KR100_13640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KR100_13645	COG0347	Belongs to the P(II) protein family
KR100_13650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KR100_13665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KR100_13685	COG1083	cytidylyl-transferase
KR100_13700	COG2089	acid synthase
KR100_13760	COG1917	Cupin 2, conserved barrel domain protein
KR100_13945	COG0116	Belongs to the methyltransferase superfamily
KR100_13965	COG3237	CsbD-like
KR100_13980	COG1196	nuclear chromosome segregation
KR100_13995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KR100_14010	COG0439	Biotin carboxylase
KR100_14025	COG0515	serine threonine protein kinase
KR100_14045	COG4178	(ABC) transporter
KR100_14050	COG0537	adenosine 5'-monophosphoramidase activity
KR100_14100	COG0242	peptide deformylase activity
KR100_14110	COG1970	mechanosensitive ion channel activity
KR100_14115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KR100_14120	COG0719	Fe-S assembly protein
KR100_14125	COG0396	ATPase activity
KR100_14130	COG0719	Fe-S assembly protein
KR100_14135	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
KR100_14155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KR100_14205	COG0033	Phosphoglucomutase
KR100_14215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KR100_14225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KR100_14245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR100_14250	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KR100_14255	COG0175	sulfate reduction
KR100_14260	COG1252	NADH dehydrogenase
KR100_14265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KR100_14270	COG0471	metal ion transport
KR100_14270	COG3273	potassium ion transport
KR100_14275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KR100_14280	COG0569	domain protein
KR100_14285	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KR100_14310	COG0488	(ABC) transporter
KR100_14320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KR100_14340	COG1643	Atp-dependent helicase
KR100_14345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KR100_14355	COG1570	exodeoxyribonuclease VII activity
KR100_14360	COG1722	exodeoxyribonuclease VII activity
KR100_14405	COG0483	inositol monophosphate 1-phosphatase activity
KR100_14420	COG1968	undecaprenyl-diphosphatase activity
KR100_14430	COG1555	photosystem II stabilization
KR100_14435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KR100_14440	COG4243	Vitamin k epoxide reductase
KR100_14445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KR100_14460	COG1032	radical SAM domain protein
KR100_14540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KR100_14545	COG0277	FAD linked oxidase domain protein
KR100_14570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KR100_14575	COG1472	Belongs to the glycosyl hydrolase 3 family
KR100_14580	COG0457	Tetratricopeptide repeat
KR100_14580	COG0463	Glycosyl transferase, family 2
KR100_14585	COG1587	Uroporphyrinogen-III synthase
KR100_14605	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KR100_14610	COG0316	Belongs to the HesB IscA family
KR100_14620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KR100_14630	COG1090	epimerase
KR100_14635	COG3263	regulation of cellular component size
KR100_14650	COG0484	heat shock protein binding
KR100_14655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KR100_14665	COG3659	wide pore channel activity
KR100_14670	COG3659	wide pore channel activity
KR100_14690	COG1215	transferase activity, transferring glycosyl groups
KR100_14715	COG1122	ATPase activity
KR100_14725	COG0745	RESPONSE REGULATOR receiver
KR100_14735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KR100_14740	COG2217	Heavy metal translocating P-type atpase
KR100_14745	COG3063	Type IV pilus biogenesis stability protein PilW
KR100_14760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KR100_14770	COG0416	fatty acid biosynthetic process
KR100_14775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KR100_14780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KR100_14795	COG1214	PFAM Peptidase M22, glycoprotease
KR100_14805	COG0617	tRNA 3'-terminal CCA addition
KR100_14810	COG0724	RNA recognition motif
KR100_14815	COG1562	ergosterol biosynthetic process
KR100_14820	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KR100_14820	COG0493	'glutamate synthase
KR100_14835	COG0583	DNA-binding transcription factor activity
KR100_14845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KR100_14850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_14865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KR100_14875	COG2197	response regulator
KR100_14885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KR100_14890	COG0713	ATP synthesis coupled electron transport
KR100_14900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KR100_14905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KR100_14910	COG0372	Belongs to the citrate synthase family
KR100_14915	COG0588	phosphoglycerate mutase activity
KR100_14930	COG1420	regulation of RNA biosynthetic process
KR100_14935	COG0133	tryptophan synthase activity
KR100_14945	COG0023	Translation Initiation Factor
KR100_14950	COG0529	Catalyzes the synthesis of activated sulfate
KR100_14955	COG0628	permease
KR100_14960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KR100_14970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KR100_14980	COG0564	pseudouridine synthase activity
KR100_14985	COG0745	RESPONSE REGULATOR receiver
KR100_14995	COG1104	cysteine desulfurase activity
KR100_15010	COG0275	rRNA processing
KR100_15015	COG0649	NAD binding
KR100_15020	COG0463	Glycosyl transferase, family 2
KR100_15020	COG1216	Glycosyl transferase, family 2
KR100_15030	COG0824	Thioesterase
KR100_15035	COG0318	PFAM AMP-dependent synthetase and ligase
KR100_15045	COG1575	Belongs to the MenA family. Type 1 subfamily
KR100_15060	COG0189	ligase activity
KR100_15065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KR100_15070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KR100_15080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KR100_15085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KR100_15090	COG0512	Glutamine amidotransferase of anthranilate synthase
KR100_15100	COG0252	asparaginase activity
KR100_15110	COG0018	arginyl-trna synthetase
KR100_15115	COG0157	Belongs to the NadC ModD family
KR100_15125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KR100_15135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KR100_15140	COG4172	Belongs to the ABC transporter superfamily
KR100_15165	COG0564	pseudouridine synthase activity
KR100_15170	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KR100_15180	COG0126	phosphoglycerate kinase activity
KR100_15200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KR100_15235	COG0167	dihydroorotate dehydrogenase activity
KR100_15240	COG0328	RNA-DNA hybrid ribonuclease activity
KR100_15250	COG0222	ribosome binding
KR100_15255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KR100_15260	COG0081	regulation of translation
KR100_15265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KR100_15270	COG0250	Participates in transcription elongation, termination and antitermination
KR100_15275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KR100_15280	COG0542	response to heat
KR100_15285	COG0346	lactoylglutathione lyase activity
KR100_15290	COG0148	phosphopyruvate hydratase activity
KR100_15320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KR100_15335	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KR100_15340	COG0237	dephospho-CoA kinase activity
KR100_15345	COG0114	fumarate hydratase activity
KR100_15355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KR100_15365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KR100_15365	COG2022	thiamine diphosphate biosynthetic process
KR100_15395	COG0105	UTP biosynthetic process
KR100_15400	COG1166	arginine decarboxylase activity
KR100_15430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KR100_15440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KR100_15475	COG0426	domain, Protein
KR100_15475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR100_15480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KR100_15480	COG0426	domain, Protein
KR100_15495	COG1741	Belongs to the pirin family
KR100_15510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KR100_15510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KR100_15515	COG0509	glycine decarboxylation via glycine cleavage system
KR100_15520	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KR100_15530	COG0359	binds to the 23S rRNA
KR100_15535	COG0305	Participates in initiation and elongation during chromosome replication
KR100_15535	COG1372	Participates in initiation and elongation during chromosome replication
KR100_15535	COG0305	Participates in initiation and elongation during chromosome replication
KR100_15535	COG1372	Participates in initiation and elongation during chromosome replication
KR100_15610	COG0445	tRNA wobble uridine modification