locus-tag	class	description
KR52_00010	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
KR52_00015	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
KR52_00025	ENOG4105DCI	Phosphohydrolase
KR52_00030	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
KR52_00040	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
KR52_00060	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
KR52_00065	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
KR52_00095	ENOG4105YVZ	photosystem II
KR52_00105	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
KR52_00110	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
KR52_00115	ENOG4107URF	beta-phospho-glucomutase
KR52_00120	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
KR52_00125	ENOG4107S5T	Carbohydrate kinase
KR52_00175	ENOG4106BTU	phycobilisome rod-core linker polypeptide
KR52_00205	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
KR52_00230	ENOG4106JQX	C-phycoerythrin class II beta chain
KR52_00235	ENOG4106QDP	C-phycoerythrin class II alpha chain
KR52_00275	ENOG4108REV	C-phycoerythrin class I alpha chain
KR52_00295	ENOG4108QAI	Catalyzes the two-electron reduction of biliverdin IX- alpha at the C15 methine bridge (By similarity)
KR52_00300	ENOG4108KKY	Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin (By similarity)
KR52_00335	ENOG4105CAT	Cytidine monophosphate kinase
KR52_00350	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
KR52_00390	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
KR52_00410	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
KR52_00420	ENOG4105CNI	cell division protein FtsW
KR52_00440	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
KR52_00445	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
KR52_00460	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
KR52_00465	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
KR52_00475	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
KR52_00500	ENOG4105EWK	phytoene
KR52_00525	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
KR52_00540	ENOG4105CD2	stage iii sporulation protein aa
KR52_00550	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR52_00555	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
KR52_00560	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
KR52_00565	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
KR52_00570	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KR52_00575	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
KR52_00580	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
KR52_00585	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
KR52_00590	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
KR52_00595	ENOG410848H	50s ribosomal protein l29
KR52_00600	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
KR52_00605	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
KR52_00610	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
KR52_00615	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KR52_00620	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
KR52_00625	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
KR52_00630	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
KR52_00635	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
KR52_00640	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
KR52_00645	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
KR52_00650	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
KR52_00655	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KR52_00660	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
KR52_00665	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR52_00670	ENOG4108ZT0	50S ribosomal protein l17
KR52_00675	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
KR52_00680	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
KR52_00685	ENOG4108UJD	30S ribosomal protein S9
KR52_00690	ENOG41082HT	Binds the 23S rRNA (By similarity)
KR52_00695	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
KR52_00705	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
KR52_00725	ENOG4105CKK	Glycosyl transferase, family 2
KR52_00740	ENOG4108W6I	photosystem I reaction center protein subunit XI
KR52_00760	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
KR52_00765	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
KR52_00775	ENOG4105E4R	Precorrin-3B C17-methyltransferase
KR52_00795	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
KR52_00820	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
KR52_00825	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
KR52_00830	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
KR52_00835	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
KR52_00840	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
KR52_00845	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
KR52_00865	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
KR52_00880	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
KR52_00885	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
KR52_00895	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
KR52_00900	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
KR52_00925	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
KR52_00945	ENOG4107RIQ	Sulfate adenylate transferase
KR52_00950	ENOG4105CPJ	photosystem II manganese-stabilizing
KR52_00995	ENOG4105CXT	aspartate transcarbamylase
KR52_01000	ENOG4108VX5	3-methyladenine DNA glycosylase
KR52_01040	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
KR52_01060	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
KR52_01080	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
KR52_01095	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
KR52_01100	ENOG4105E4C	Lytic transglycosylase catalytic
KR52_01120	ENOG4105DHP	deoxycytidine triphosphate deaminase
KR52_01130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
KR52_01140	ENOG4108R0D	protein with myosin-like
KR52_01155	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
KR52_01160	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
KR52_01165	ENOG4105WIA	photosystem II reaction center protein H
KR52_01170	ENOG410686T	photosystem II reaction center protein N
KR52_01180	ENOG4106A1F	This protein is a component of the reaction center of photosystem II (By similarity)
KR52_01200	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
KR52_01205	ENOG4105CEV	competence damage-inducible protein
KR52_01210	ENOG4105ESV	Glycosyl transferase, family 4
KR52_01215	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
KR52_01245	ENOG4105PW4	Sugar fermentation stimulation protein homolog
KR52_01255	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
KR52_01270	ENOG4105DC1	bifunctional purine biosynthesis protein purh
KR52_01290	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
KR52_01295	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
KR52_01300	ENOG4106815	This protein is a component of the reaction center of photosystem II (By similarity)
KR52_01315	ENOG4107TYG	Oxidoreductase domain-containing protein
KR52_01320	ENOG4105C37	(CBS) domain
KR52_01330	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
KR52_01335	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
KR52_01345	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
KR52_01350	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
KR52_01370	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
KR52_01375	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
KR52_01410	ENOG4105CPF	Cell wall formation (By similarity)
KR52_01425	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
KR52_01430	ENOG4108YZ4	nudix hydrolase
KR52_01445	ENOG4105EET	magnesium chelatase
KR52_01455	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KR52_01460	ENOG4105CHW	UPF0052 protein
KR52_01465	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KR52_01470	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR52_01475	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KR52_01480	ENOG410828V	rubredoxin
KR52_01485	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
KR52_01490	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
KR52_01495	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
KR52_01550	ENOG4105C30	Nad-dependent epimerase dehydratase
KR52_01555	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
KR52_01565	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
KR52_01575	ENOG4105CUT	histidyl-tRNA synthetase
KR52_01580	ENOG4105CMR	udp-glucose 4-epimerase
KR52_01585	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
KR52_01600	ENOG4105C2X	Arabinose 5-phosphate isomerase
KR52_01605	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
KR52_01610	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
KR52_01635	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
KR52_01650	ENOG4105JNK	Glycosyl transferase (Group 1
KR52_01655	ENOG4107TYR	Glycosyl Transferase
KR52_01660	ENOG4107TAE	Glycosyl transferase (Group 1
KR52_01685	ENOG4107W7X	Aldolase
KR52_01690	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
KR52_01700	ENOG4105CKK	Glycosyl transferase, family 2
KR52_01705	ENOG4108HMX	isocitrate dehydrogenase (NADP)
KR52_01720	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
KR52_01730	ENOG4105EU8	FAD linked oxidase domain protein
KR52_01755	ENOG4107QRI	Phosphoketolase
KR52_01765	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
KR52_01785	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
KR52_01790	ENOG4105EYW	Ion transport protein
KR52_01800	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
KR52_01810	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
KR52_01815	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
KR52_01820	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
KR52_01830	ENOG4105CV1	Transketolase (EC 2.2.1.1)
KR52_01835	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
KR52_01860	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
KR52_01865	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
KR52_01875	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
KR52_01880	ENOG41067HS	methyltransferase
KR52_01900	ENOG4105CRK	lysyL-tRNA synthetase
KR52_01920	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
KR52_01935	ENOG4107T5V	SNARE associated Golgi
KR52_01940	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
KR52_01945	ENOG4105K8N	protein family UPF0079, ATPase
KR52_01950	ENOG4105D7K	pfkb domain protein
KR52_01955	ENOG4105CEN	a g-specific adenine glycosylase
KR52_02000	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_02005	ENOG4105CJW	magnesium transporter
KR52_02015	ENOG4107KCI	Protein CrcB homolog
KR52_02020	ENOG41086BQ	Protein CrcB homolog
KR52_02035	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
KR52_02040	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
KR52_02050	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
KR52_02055	ENOG4105D7W	serine acetyltransferase
KR52_02060	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
KR52_02070	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
KR52_02080	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
KR52_02090	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
KR52_02095	ENOG4105ZDH	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
KR52_02105	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
KR52_02135	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
KR52_02140	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
KR52_02145	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
KR52_02150	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR52_02155	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
KR52_02165	ENOG4105C6E	dna polymerase iii
KR52_02175	ENOG4105JFG	SpoIID LytB domain protein
KR52_02180	ENOG41084A0	50s ribosomal protein L35
KR52_02185	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
KR52_02200	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
KR52_02210	ENOG4105CMR	udp-glucose 4-epimerase
KR52_02220	ENOG4107RF6	penicillin-binding protein
KR52_02240	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
KR52_02245	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
KR52_02305	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
KR52_02310	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
KR52_02315	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
KR52_02325	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
KR52_02335	ENOG4105DFU	Cell wall formation (By similarity)
KR52_02340	ENOG4105D4A	Cell wall formation (By similarity)
KR52_02345	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
KR52_02350	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
KR52_02360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
KR52_02365	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KR52_02370	ENOG4107QHF	type ii secretion system protein e
KR52_02375	ENOG4105CZX	twitching motility protein
KR52_02385	ENOG4105CBX	hi0933 family
KR52_02390	ENOG4105E0X	reductase
KR52_02400	ENOG4105VFU	Rna-binding protein
KR52_02405	ENOG4105CH7	arginosuccinase
KR52_02410	ENOG4107SGM	protein serine threonine phosphatase
KR52_02420	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
KR52_02435	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
KR52_02450	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
KR52_02455	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
KR52_02465	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
KR52_02500	ENOG4107STW	synthase
KR52_02505	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
KR52_02510	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
KR52_02540	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
KR52_02555	ENOG4105CDH	Citrulline--aspartate ligase
KR52_02565	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
KR52_02575	ENOG4105E2X	shikimate dehydrogenase
KR52_02580	ENOG4105CFG	Acts as a chaperone (By similarity)
KR52_02605	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
KR52_02610	ENOG4105CMQ	Chloride channel
KR52_02620	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
KR52_02630	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_02635	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
KR52_02650	ENOG4108I0Q	anthranilate phosphoribosyltransferase
KR52_02660	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
KR52_02670	ENOG4105TMB	Formate nitrite transporter
KR52_02680	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
KR52_02700	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
KR52_02710	ENOG4108ZAF	Molybdopterin
KR52_02725	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
KR52_02730	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
KR52_02750	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
KR52_02755	ENOG4107R3J	Transporter
KR52_02760	ENOG410838B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
KR52_02765	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
KR52_02805	ENOG4105CXT	aspartate transcarbamylase
KR52_02810	ENOG4105CAQ	asparagine synthetase
KR52_02835	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
KR52_02840	ENOG4105CQM	Urea amidohydrolase subunit alpha
KR52_02845	ENOG4105KI2	Urea amidohydrolase subunit beta
KR52_02850	ENOG4108YZ9	Urea amidohydrolase subunit gamma
KR52_02855	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
KR52_02860	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
KR52_02865	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
KR52_02870	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
KR52_02875	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
KR52_02880	ENOG4105C32	Amino acid ABC transporter (Permease)
KR52_02890	ENOG4105C0Z	ABC transporter
KR52_02895	ENOG4108IV0	ABC, transporter
KR52_02910	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
KR52_02930	ENOG4105C3Q	Glycosyl transferase, family 2
KR52_02935	ENOG4107QW3	Sucrose phosphorylase
KR52_02955	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
KR52_02960	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
KR52_02965	ENOG4107U96	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
KR52_02970	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
KR52_02980	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_02985	ENOG4105C9M	aspartyl-trna synthetase
KR52_02990	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
KR52_03005	ENOG4105CYW	agmatinase
KR52_03010	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
KR52_03020	ENOG4105DXN	mazG family
KR52_03095	ENOG4105PDP	Short chain dehydrogenase
KR52_03100	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
KR52_03130	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
KR52_03135	ENOG4105CJ1	ABC, transporter
KR52_03150	ENOG4105BZU	Histidine kinase
KR52_03170	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
KR52_03210	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
KR52_03215	ENOG4105CDU	Replicative dna helicase
KR52_03215	ENOG4105CDU	Replicative dna helicase
KR52_03220	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
KR52_03230	ENOG4105CXI	aluminum resistance protein
KR52_03235	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
KR52_03240	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KR52_03270	ENOG4105CNW	domain protein
KR52_03290	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
KR52_03300	ENOG4105CH5	extracellular solute-binding protein, family 7
KR52_03325	ENOG4105C0D	helicase
KR52_03335	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
KR52_03345	ENOG4105F8J	Adenylate Guanylate cyclase
KR52_03355	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
KR52_03360	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
KR52_03395	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
KR52_03430	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
KR52_03440	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
KR52_03465	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
KR52_03470	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
KR52_03530	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
KR52_03540	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
KR52_03555	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
KR52_03560	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
KR52_03565	ENOG4107Z3D	50S ribosomal protein l10
KR52_03570	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
KR52_03580	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
KR52_03585	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
KR52_03620	ENOG4105CIH	Imidazole acetol-phosphate transaminase
KR52_03625	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
KR52_03645	ENOG4105BZA	Phosphoglycerate kinase
KR52_03650	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
KR52_03665	ENOG4106A3M	Cytochrome p-450
KR52_03685	ENOG4108JQ6	ABC transporter
KR52_03700	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
KR52_03705	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
KR52_03720	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
KR52_03725	ENOG4105C0A	alcohol dehydrogenase
KR52_03735	ENOG4105C75	arginyL-tRNA synthetase
KR52_03740	ENOG4105BZU	Histidine kinase
KR52_03780	ENOG4105BZU	Histidine kinase
KR52_03785	ENOG4105D64	Mechanosensitive ion channel
KR52_03815	ENOG4105IRW	patatin-like phospholipase family protein
KR52_03820	ENOG4105CIH	Imidazole acetol-phosphate transaminase
KR52_03825	ENOG4105HDK	L-asparaginase
KR52_03845	ENOG4105DDQ	anthranilate synthase
KR52_03855	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
KR52_03865	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
KR52_03875	ENOG4105D7Z	glutathione synthase
KR52_03880	ENOG4105E4F	Isochorismate synthase
KR52_03895	ENOG4105CEY	Amp-dependent synthetase and ligase
KR52_03900	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
KR52_03920	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR52_03925	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
KR52_03935	ENOG4105C3J	Cysteine desulfurase
KR52_03945	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
KR52_03985	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
KR52_04000	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
KR52_04005	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
KR52_04030	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
KR52_04035	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR52_04045	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR52_04050	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
KR52_04055	ENOG41080ZE	Adenylate cyclase
KR52_04085	ENOG4105C8S	subunit m
KR52_04110	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR52_04115	ENOG4105CVN	desaturase
KR52_04120	ENOG4105FE1	phytoene synthase
KR52_04130	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KR52_04140	ENOG41072GX	Peptidase M22 Glycoprotease
KR52_04150	ENOG4105CEY	Amp-dependent synthetase and ligase
KR52_04160	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
KR52_04165	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
KR52_04180	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
KR52_04185	ENOG4105C59	p-type ATPase
KR52_04190	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
KR52_04200	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
KR52_04210	ENOG4108JJB	ABC transporter
KR52_04215	ENOG4105VUV	UPF0367 protein
KR52_04220	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
KR52_04270	ENOG4108PWY	Carbohydrate-selective porin OprB
KR52_04275	ENOG4108PWY	Carbohydrate-selective porin OprB
KR52_04285	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
KR52_04295	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR52_04330	ENOG4105CVN	desaturase
KR52_04345	ENOG4108DIF	synthase (EC 4.2.1.75)
KR52_04350	ENOG4107TVC	Glycosyl transferase, family 2
KR52_04355	ENOG4105D17	glycoside hydrolase, family 3 domain protein
KR52_04360	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
KR52_04385	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
KR52_04405	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
KR52_04425	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
KR52_04430	ENOG4105CVB	Vitamin K epoxide reductase
KR52_04435	ENOG4108IYU	L-aspartate oxidase
KR52_04440	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
KR52_04450	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
KR52_04540	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
KR52_04555	ENOG4105CQ7	ATP-dependent helicase
KR52_04585	ENOG4105C5H	ABC transporter
KR52_04610	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
KR52_04615	ENOG4107ZYR	domain protein
KR52_04620	ENOG4105CZN	Potassium uptake protein
KR52_04630	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
KR52_04640	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
KR52_04645	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
KR52_04650	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR52_04665	ENOG4105D1H	recombination factor protein RarA
KR52_04670	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
KR52_04675	ENOG4105BZS	acriflavin resistance protein
KR52_04685	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
KR52_04720	ENOG4106BTU	phycobilisome rod-core linker polypeptide
KR52_04780	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
KR52_04800	ENOG4105C0P	Mg chelatase subunit ChlI
KR52_04805	ENOG4107YU2	histidine triad (hIT) protein
KR52_04815	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR52_04835	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
KR52_04845	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
KR52_04860	ENOG4105E0X	reductase
KR52_04890	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
KR52_04985	ENOG4105D2T	synthase
KR52_05000	ENOG4105F0R	Cytidylyltransferase
KR52_05005	ENOG4105E12	capsule polysaccharide
KR52_05020	ENOG4107ADV	acyl carrier protein
KR52_05045	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
KR52_05050	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
KR52_05090	ENOG4105EEK	Polypeptide
KR52_05095	ENOG4107SWE	Methyltransferase
KR52_05105	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
KR52_05110	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR52_05115	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR52_05125	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KR52_05130	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
KR52_05135	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
KR52_05160	ENOG4105K5B	UPF0225 protein
KR52_05165	ENOG4105DCF	alanine dehydrogenase
KR52_05180	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
KR52_05190	ENOG4107RAQ	aminopeptidase
KR52_05195	ENOG4105EWV	Sodium calcium exchanger membrane region
KR52_05205	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
KR52_05210	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
KR52_05215	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
KR52_05220	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
KR52_05225	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
KR52_05260	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
KR52_05265	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
KR52_05280	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
KR52_05290	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
KR52_05315	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
KR52_05340	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
KR52_05355	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
KR52_05360	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
KR52_05365	ENOG4105JFG	SpoIID LytB domain protein
KR52_05370	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
KR52_05425	ENOG4105CDY	transcriptional regulatory protein
KR52_05430	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
KR52_05440	ENOG4105K46	50S ribosomal protein l27
KR52_05445	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
KR52_05450	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
KR52_05455	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
KR52_05460	ENOG4105EHU	Circadian clock protein KaiC
KR52_05470	ENOG4105C12	Phosphoribosylglycinamide synthetase
KR52_05480	ENOG4107QPR	SAICAR synthetase
KR52_05490	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR52_05495	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
KR52_05505	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR52_05510	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
KR52_05525	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
KR52_05560	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
KR52_05565	ENOG4105CUV	Homoserine Kinase
KR52_05570	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
KR52_05575	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
KR52_05615	ENOG4105K70	DNA-binding protein
KR52_05620	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
KR52_05830	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
KR52_05840	ENOG4105CHV	Transcription elongation factor NusA
KR52_05845	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
KR52_05875	ENOG4105C0H	protease
KR52_05880	ENOG4105E66	phosphoriboisomerase A
KR52_05885	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
KR52_05890	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
KR52_05900	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR52_05905	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR52_05910	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KR52_05915	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR52_05920	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KR52_05950	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
KR52_05960	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
KR52_05975	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
KR52_05990	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
KR52_06005	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
KR52_06010	ENOG4105C09	Bile acid
KR52_06015	ENOG4105C09	Bile acid
KR52_06055	ENOG4105CQR	helicase
KR52_06060	ENOG4105C9Q	fumarate hydratase class II
KR52_06090	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
KR52_06100	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
KR52_06105	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
KR52_06130	ENOG4107QZ7	Cellulose synthase catalytic subunit
KR52_06135	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
KR52_06140	ENOG4107U45	Cobalt transport protein
KR52_06150	ENOG4105DFA	alanine racemase domain protein
KR52_06155	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
KR52_06170	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
KR52_06190	ENOG4105E2K	Glycosyl transferase (Group 1
KR52_06200	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
KR52_06205	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
KR52_06215	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
KR52_06220	ENOG4108IQE	Amp-dependent synthetase and ligase
KR52_06280	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
KR52_06285	ENOG4105C6T	cysteine synthase
KR52_06305	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
KR52_06310	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
KR52_06325	ENOG41081E8	Alpha beta hydrolase
KR52_06350	ENOG41089UC	methyltransferase, type 11
KR52_06355	ENOG4108R99	pseudouridine synthase
KR52_06360	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
KR52_06365	ENOG4105C3M	thioredoxin reductase
KR52_06395	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KR52_06400	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KR52_06405	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KR52_06415	ENOG4105NZG	Ferredoxin
KR52_06420	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
KR52_06425	ENOG4105C8J	)-transporter
KR52_06440	ENOG4105C8N	cysteinyl-tRNA synthetase
KR52_06455	ENOG4105C3G	gtp-binding protein
KR52_06475	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
KR52_06505	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
KR52_06510	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
KR52_06530	ENOG4106FVC	RNA methyltransferase
KR52_06545	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
KR52_06550	ENOG4105K63	Thioredoxin
KR52_06555	ENOG4107QVP	Dehydrogenase
KR52_06560	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
KR52_06575	ENOG4108JT6	LycopEne
KR52_06580	ENOG4107RFW	hydrolase family 57
KR52_06585	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
KR52_06590	ENOG4105DRS	transport system, permease
KR52_06630	ENOG4105C34	Pseudouridine synthase
KR52_06640	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
KR52_06660	ENOG4107QYX	exodeoxyribonuclease v alpha
KR52_06670	ENOG4105CVJ	phosphoglycerate mutase
KR52_06685	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
KR52_06690	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
KR52_06720	ENOG4105BZU	Histidine kinase
KR52_06735	ENOG4105CD8	aminopeptidase N
KR52_06810	ENOG4105EYW	Ion transport protein
KR52_06835	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
KR52_06855	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
KR52_06935	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
KR52_06945	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
KR52_06960	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
KR52_06990	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
KR52_07005	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
KR52_07010	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KR52_07015	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
KR52_07020	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
KR52_07035	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
KR52_07050	ENOG4107R1Y	fructose-bisphosphate aldolase
KR52_07070	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
KR52_07090	ENOG4105D64	Mechanosensitive ion channel
KR52_07100	ENOG4105KBH	arsR family transcriptional regulator
KR52_07105	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
KR52_07135	ENOG4105CSR	polyphosphate kinase 2
KR52_07145	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
KR52_07170	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
KR52_07195	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
KR52_07200	ENOG4105DHT	Metal Dependent Phosphohydrolase
KR52_07205	ENOG4105CTK	cobaltochelatase, cobn subunit
KR52_07235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KR52_07270	ENOG4105DDI	hemolysin-type calcium-binding region
KR52_07280	ENOG4105BZ1	(ABC) transporter
KR52_07310	ENOG4105CP7	Triose-phosphate isomerase
KR52_07320	ENOG4105BZ1	(ABC) transporter
KR52_07330	ENOG4105BZG	amino acid carrier protein
KR52_07340	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
KR52_07380	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
KR52_07390	ENOG4105CHH	sulfate transporter
KR52_07400	ENOG4107QXX	ABC transporter
KR52_07405	ENOG4105EZ7	amino acid ABC transporter
KR52_07410	ENOG4105DRP	amino acid AbC transporter
KR52_07415	ENOG4105CDA	abc transporter atp-binding protein
KR52_07450	ENOG4105CVG	Homoserine O-transsuccinylase
KR52_07455	ENOG4108IQK	o-acetylhomoserine
KR52_07525	ENOG4107XWZ	ferric uptake regulator
KR52_07540	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
KR52_07580	ENOG4105DGU	Histone deacetylase
KR52_07855	ENOG4108Z0R	Transferase
KR52_07860	ENOG41076WT	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II (By similarity)
KR52_07865	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
KR52_07930	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
KR52_07950	ENOG4105DSY	exodeoxyribonuclease V, gamma
KR52_07965	ENOG4105C7H	Helicase, RecD TraA family
KR52_07970	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
KR52_07975	ENOG4105C1J	atp-dependent rna helicase
KR52_07990	ENOG4105VFU	Rna-binding protein
KR52_08000	ENOG4105BZ1	(ABC) transporter
KR52_08025	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
KR52_08030	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
KR52_08040	ENOG4108K3A	Glutathione S-transferase
KR52_08045	ENOG4105C72	UPF0176 protein
KR52_08060	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
KR52_08065	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
KR52_08070	ENOG4105C8B	TIGR00159 family
KR52_08095	ENOG4108MUZ	hydrolase
KR52_08115	ENOG4105CXN	decarboxylase
KR52_08140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KR52_08145	ENOG4105EB3	Histidine kinase
KR52_08180	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
KR52_08205	ENOG4105CC5	ABC transporter
KR52_08210	ENOG4105DIK	(ABC) transporter
KR52_08235	ENOG4108PJD	permease
KR52_08290	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
KR52_08300	ENOG4108PWY	Carbohydrate-selective porin OprB
KR52_08325	ENOG4107E2E	PKHD-type hydroxylase
KR52_08335	ENOG4108PWY	Carbohydrate-selective porin OprB
KR52_08425	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
KR52_08475	ENOG4108IAB	Phoh family
KR52_08480	ENOG4108URH	decarboxylase
KR52_08510	ENOG4105D64	Mechanosensitive ion channel
KR52_08605	ENOG4105DMF	Dehydrogenase
KR52_08705	ENOG4105F8C	transglutaminase domain-containing protein
KR52_08715	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
KR52_08740	ENOG4105VFU	Rna-binding protein
KR52_08755	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
KR52_08855	ENOG4105CSM	endonuclease III
KR52_08860	ENOG4105DSE	periplasmic solute binding protein
KR52_08905	ENOG4105DKW	ABC transporter
KR52_08940	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
KR52_09105	ENOG4107QRT	dEAD DEAH box helicase
KR52_09110	ENOG4107T0X	DNA ligase
KR52_09170	ENOG4105D49	3-dehydroquinate synthase
KR52_09175	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
KR52_09180	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
KR52_09235	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
KR52_09240	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR52_09250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
KR52_09270	ENOG4108VIA	integral membrane protein
KR52_09280	ENOG4105C7B	Threonine dehydratase
KR52_09285	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
KR52_09290	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
KR52_09295	ENOG4105VGQ	Photosystem I subunit X
KR52_09440	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
KR52_09450	ENOG4107T3P	ABC, transporter
KR52_09460	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR52_09465	ENOG41083EU	50s ribosomal protein l28
KR52_09470	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
KR52_09480	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
KR52_09500	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
KR52_09505	ENOG4105E2Z	phosphate ABC transporter (Permease
KR52_09510	ENOG4105C8U	phosphate abc transporter
KR52_09515	ENOG4108KBA	Acts as a chaperone (By similarity)
KR52_09520	ENOG4105DVC	DnaJ domain protein
KR52_09530	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KR52_09535	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
KR52_09540	ENOG4108ZCU	PPIases accelerate the folding of proteins
KR52_09550	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
KR52_09555	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
KR52_09590	ENOG4105C89	phosphohexose isomerase
KR52_09595	ENOG4105C8T	Leucyl-tRNA synthetase
KR52_09605	ENOG4105VTR	Integrase
KR52_09635	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
KR52_09640	ENOG4107QI6	Cysteine desulfurase
KR52_09655	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
KR52_09665	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
KR52_09675	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
KR52_09685	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
KR52_09705	ENOG4105CTK	cobaltochelatase, cobn subunit
KR52_09740	ENOG4105JFG	SpoIID LytB domain protein
KR52_09755	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_09785	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
KR52_09790	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
KR52_09795	ENOG41084GG	50S ribosomal protein L33
KR52_09800	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
KR52_09840	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
KR52_09845	ENOG4108YZT	Adenosylcobinamide kinase
KR52_09855	ENOG4105DR5	peptidase
KR52_09875	ENOG4105DJZ	UPF0182 protein
KR52_09895	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
KR52_09900	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
KR52_09945	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
KR52_09960	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
KR52_09995	ENOG4107TS3	membrane protein, TerC
KR52_10065	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
KR52_10070	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
KR52_10085	ENOG4107T9Q	phosphonate abc transporter
KR52_10090	ENOG4105D5T	phosphonate abc transporter
KR52_10115	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_10145	ENOG4108JJB	ABC transporter
KR52_10150	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
KR52_10165	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
KR52_10175	ENOG4107VC8	ATP cone domain protein
KR52_10300	ENOG4108URH	decarboxylase
KR52_10365	ENOG4107QRP	cobalamin biosynthesis protein CobW
KR52_10370	ENOG4105N7N	Pentapeptide repeat-containing protein
KR52_10375	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
KR52_10385	ENOG4105C01	Dihydroxy-acid dehydratase
KR52_10405	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
KR52_10410	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
KR52_10415	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
KR52_10420	ENOG4105CBT	Fructose-1,6-bisphosphatase
KR52_10440	ENOG4105CRE	cytochrome C
KR52_10450	ENOG4108IUZ	ABC transporter
KR52_10470	ENOG4105CFP	Peptidase U32
KR52_10490	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
KR52_10495	ENOG4107QHM	Sulfite reductase
KR52_10515	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
KR52_10520	ENOG4105CE9	30S ribosomal protein S2
KR52_10525	ENOG4107R51	Glycosyl transferase, family 2
KR52_10550	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
KR52_10560	ENOG4105C1V	Peptidase, M16
KR52_10575	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
KR52_10590	ENOG4108Z6B	deaminase
KR52_10595	ENOG4105C5R	Aminotransferase
KR52_10600	ENOG4108TCG	allophycocyanin beta subunit
KR52_10605	ENOG4105C5F	glutamine synthetase
KR52_10615	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
KR52_10640	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
KR52_10645	ENOG4105MSA	Photosystem II reaction center W protein
KR52_10650	ENOG4105DSF	transport protein
KR52_10675	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
KR52_10680	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
KR52_10700	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
KR52_10705	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
KR52_10710	ENOG4107JDS	UPF0102 protein
KR52_10725	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
KR52_10745	ENOG4105KT5	UmuD protein
KR52_10750	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
KR52_10770	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
KR52_10775	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
KR52_10785	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
KR52_10790	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
KR52_10805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
KR52_10825	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KR52_10835	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
KR52_10840	ENOG4108I0Q	anthranilate phosphoribosyltransferase
KR52_10845	ENOG4105BZ1	(ABC) transporter
KR52_10910	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
KR52_10915	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
KR52_10925	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
KR52_10930	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KR52_10940	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
KR52_10945	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
KR52_10955	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
KR52_10960	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
KR52_10970	ENOG4108N5B	2-phosphosulfolactate phosphatase
KR52_10980	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
KR52_10990	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
KR52_11005	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
KR52_11010	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
KR52_11015	ENOG4108IPT	Naphthoate synthase
KR52_11020	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
KR52_11050	ENOG4105CVR	type I restriction-modification system
KR52_11055	ENOG4105EKX	Restriction modification system DNA (Specificity
KR52_11060	ENOG4105DZR	Type I site-specific deoxyribonuclease
KR52_11070	ENOG4105CGY	Dna recombination protein
KR52_11110	ENOG4108RXX	maleylacetoacetate isomerase
KR52_11145	ENOG4105D6J	arsenicaL-resistance protein
KR52_11155	ENOG4105D5T	phosphonate abc transporter
KR52_11160	ENOG4107T9Q	phosphonate abc transporter
KR52_11185	ENOG4108JUB	Transcriptional regulator
KR52_11195	ENOG4107QRI	Phosphoketolase
KR52_11200	ENOG4105BZU	Histidine kinase
KR52_11205	ENOG4105QUW	
KR52_11220	ENOG410802X	bacteriophage n4 adsorption protein b
KR52_11285	ENOG4105EQ0	Major Facilitator superfamily
KR52_11335	ENOG4105C4W	S-formylglutathione hydrolase
KR52_11345	ENOG4105BZU	Histidine kinase
KR52_11385	ENOG4105JZI	cytochrome P450
KR52_11410	ENOG4107RA9	decarboxylase
KR52_11440	ENOG4105CFQ	glutamine synthetase
KR52_11450	ENOG4107QN1	sodium solute
KR52_11455	ENOG4105BZU	Histidine kinase
KR52_11680	ENOG410848W	30S ribosomal protein S21
KR52_11765	ENOG4105EJ9	Membrane
KR52_11825	ENOG4105C09	Bile acid
KR52_11830	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
KR52_11855	ENOG4105C31	Tryptophanyl-tRNA synthetase
KR52_11870	ENOG4105C22	threonyL-tRNA synthetase
KR52_11880	ENOG4105CHC	glucokinase (EC 2.7.1.2)
KR52_11885	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
KR52_11890	ENOG4105C8S	subunit m
KR52_11895	ENOG4105DGW	oligopeptidase A
KR52_11910	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
KR52_11950	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
KR52_11955	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
KR52_11965	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
KR52_11970	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
KR52_12005	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
KR52_12015	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
KR52_12035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_12070	ENOG4105TQG	cytochrome C, class I
KR52_12085	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
KR52_12095	ENOG41069EW	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
KR52_12120	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
KR52_12140	ENOG4105EKE	dihydroorotase
KR52_12145	ENOG4105CHH	sulfate transporter
KR52_12215	ENOG4105DC8	reductase
KR52_12235	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
KR52_12240	ENOG4105C0H	protease
KR52_12255	ENOG4107WJM	-acetyltransferase
KR52_12260	ENOG4105BZ1	(ABC) transporter
KR52_12265	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
KR52_12270	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
KR52_12275	ENOG4105KME	endoribonuclease L-psp
KR52_12315	ENOG4105DBV	ornithine carbamoyltransferase
KR52_12325	ENOG4108RAV	Conserved protein
KR52_12375	ENOG4105ETX	regulatoR
KR52_12380	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
KR52_12385	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
KR52_12390	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
KR52_12400	ENOG4108JJA	ABC, transporter
KR52_12435	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
KR52_12440	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
KR52_12455	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
KR52_12465	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
KR52_12495	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
KR52_12505	ENOG4105HFZ	Membrane
KR52_12515	ENOG41082B1	30S ribosomal protein S16
KR52_12520	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KR52_12530	ENOG4108JYK	Dehydrogenase
KR52_12535	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_12540	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
KR52_12545	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
KR52_12550	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
KR52_12580	ENOG4108ZE9	Monovalent cation H antiporter subunit C
KR52_12585	ENOG4105D65	subunit l
KR52_12615	ENOG4105DK0	Indole-3-glycerol phosphate synthase
KR52_12640	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
KR52_12645	ENOG4105C8Y	Acetylornithine aminotransferase
KR52_12650	ENOG4105C8Y	Acetylornithine aminotransferase
KR52_12655	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
KR52_12660	ENOG4105N7N	Pentapeptide repeat-containing protein
KR52_12690	ENOG4105DTQ	mandelate racemase muconate lactonizing
KR52_12695	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
KR52_12700	ENOG4105CPF	Cell wall formation (By similarity)
KR52_12715	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
KR52_12720	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
KR52_12735	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR52_12740	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KR52_12745	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
KR52_12755	ENOG4105D3Q	Sugar transferase
KR52_12855	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
KR52_12890	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
KR52_12895	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
KR52_12905	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
KR52_12910	ENOG4108JQC	penicillin-binding protein 1A
KR52_12920	ENOG41080UX	Methyltransferase
KR52_12925	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
KR52_12940	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
KR52_12945	ENOG4105GR3	Histidine kinase
KR52_12980	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KR52_12985	ENOG41062D9	Histidine kinase
KR52_12990	ENOG4108VAU	general secretion pathway protein G
KR52_13035	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
KR52_13040	ENOG410814C	multidrug resistance protein
KR52_13045	ENOG4105DWT	malate dehydrogenase (quinone)
KR52_13050	ENOG41083MR	nifu domain-containing protein
KR52_13085	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
KR52_13095	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
KR52_13110	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
KR52_13120	ENOG4108Z03	MAF-like protein
KR52_13130	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
KR52_13145	ENOG4106F1P	AAA ATPase, central domain protein
KR52_13160	ENOG4105C8S	subunit m
KR52_13170	ENOG4105KNY	Microcompartments protein
KR52_13195	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
KR52_13200	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
KR52_13205	ENOG4105KNY	Microcompartments protein
KR52_13210	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
KR52_13225	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
KR52_13230	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
KR52_13235	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
KR52_13265	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
KR52_13275	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
KR52_13280	ENOG4105EUJ	GTP cyclohydrolase i
KR52_13285	ENOG4107GJV	short-chain dehydrogenase reductase
KR52_13290	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
KR52_13295	ENOG4105E6N	shikimate quinate 5-dehydrogenase
KR52_13300	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
KR52_13310	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
KR52_13325	ENOG4105DZ0	fad dependent oxidoreductase
KR52_13345	ENOG4105C7K	acetolactate synthase
KR52_13350	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR52_13360	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
KR52_13365	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
KR52_13375	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
KR52_13380	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
KR52_13405	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
KR52_13420	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
KR52_13425	ENOG4105CJN	penicillin-binding protein
KR52_13440	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
KR52_13470	ENOG4105F0N	pyrophosphate phospho-hydrolase
KR52_13480	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
KR52_13490	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
KR52_13510	ENOG4105QUC	reductase
KR52_13530	ENOG4105CAS	nag kinase
KR52_13545	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KR52_13555	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
KR52_13575	ENOG4105F0N	pyrophosphate phospho-hydrolase
KR52_13580	ENOG4105CTD	carboxy-peptidase
KR52_13610	ENOG4105KZX	Pterin carbinolamine dehydratase
KR52_13615	ENOG4105CKI	cobalamin synthesis protein
KR52_13625	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KR52_13645	ENOG4105C8M	UPF0272 protein
KR52_13650	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
KR52_13670	ENOG4105CGK	Exodeoxyribonuclease III
KR52_13675	ENOG4105CQB	FAD linked oxidase domain protein
KR52_13680	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
KR52_13690	ENOG4105KG3	cytidine deaminase
KR52_13700	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
KR52_13715	ENOG4108VPT	UPF0234 protein
KR52_13755	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
KR52_13775	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
KR52_13795	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
KR52_13805	ENOG4105CZX	twitching motility protein
KR52_13810	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KR52_13815	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
KR52_13825	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
KR52_13830	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
KR52_13835	ENOG4105F23	Fibronectin-binding protein
KR52_13850	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
KR52_13855	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
KR52_13860	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
KR52_13865	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
KR52_13880	ENOG4105C9X	ppx gppa phosphatase
KR52_13895	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
KR52_13920	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
KR52_13925	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
KR52_13945	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
KR52_13950	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
KR52_13995	ENOG4108K7V	UPF0284 protein
KR52_14010	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
KR52_14015	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KR52_14020	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
KR52_14030	ENOG4105E0F	Histidine kinase
KR52_14040	ENOG4105ETX	regulatoR
KR52_14045	ENOG4105DR5	peptidase
KR52_14050	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
KR52_14055	ENOG4105CHM	Aminotransferase
KR52_14060	ENOG4105K63	Thioredoxin
KR52_14075	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
KR52_14105	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
KR52_14115	ENOG4107RIX	inner membrane protein translocase component YidC
KR52_14125	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
KR52_14135	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
KR52_14140	ENOG4105DZP	Membrane-associated zinc metalloprotease
KR52_14145	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
KR52_14150	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
KR52_14155	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
KR52_14315	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
KR52_14330	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
KR52_14335	ENOG4105CHF	Glutathione S-transferase
KR52_14345	ENOG4105C5H	ABC transporter
KR52_14360	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KR52_14365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KR52_14380	ENOG4105D52	delta-aminolevulinic acid dehydratase
KR52_14390	ENOG4105CVB	Vitamin K epoxide reductase
KR52_14395	ENOG4105CHH	sulfate transporter
KR52_14405	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
KR52_14425	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
KR52_14430	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
KR52_14440	ENOG4105C26	Dehydrogenase
KR52_14450	ENOG4105C9U	ATP-dependent DNA helicase RecQ
KR52_14460	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
KR52_14465	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
KR52_14470	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
KR52_14475	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)