locus-tag	class	description
SynMVIR181_00001	COG0592	DNA-directed DNA polymerase activity
SynMVIR181_00003	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynMVIR181_00004	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SynMVIR181_00005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynMVIR181_00007	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynMVIR181_00010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynMVIR181_00011	COG0552	protein localization to endoplasmic reticulum
SynMVIR181_00013	COG2208	phosphoserine phosphatase activity
SynMVIR181_00014	COG0165	Argininosuccinate lyase
SynMVIR181_00015	COG0724	RNA recognition motif
SynMVIR181_00016	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynMVIR181_00017	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynMVIR181_00018	COG2081	HI0933 family
SynMVIR181_00019	COG1459	type II secretion system
SynMVIR181_00021	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynMVIR181_00022	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynMVIR181_00023	COG0484	heat shock protein binding
SynMVIR181_00025	COG1162	GTPase activity
SynMVIR181_00026	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynMVIR181_00027	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynMVIR181_00028	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynMVIR181_00030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynMVIR181_00031	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynMVIR181_00032	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynMVIR181_00033	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynMVIR181_00034	COG0511	ligase activity, forming carbon-carbon bonds
SynMVIR181_00035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynMVIR181_00051	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynMVIR181_00052	COG0519	Catalyzes the synthesis of GMP from XMP
SynMVIR181_00052	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynMVIR181_00055	COG0768	penicillin binding
SynMVIR181_00056	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynMVIR181_00056	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_00057	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynMVIR181_00059	COG2022	thiamine diphosphate biosynthetic process
SynMVIR181_00062	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynMVIR181_00063	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynMVIR181_00064	COG2385	sporulation resulting in formation of a cellular spore
SynMVIR181_00065	COG1215	transferase activity, transferring glycosyl groups
SynMVIR181_00066	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynMVIR181_00068	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynMVIR181_00069	COG0740	serine-type endopeptidase activity
SynMVIR181_00070	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynMVIR181_00072	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynMVIR181_00073	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynMVIR181_00074	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynMVIR181_00076	COG0037	tRNA processing
SynMVIR181_00079	COG0556	nucleotide-excision repair
SynMVIR181_00082	COG2082	Precorrin-8x methylmutase
SynMVIR181_00083	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynMVIR181_00085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynMVIR181_00088	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_00090	COG0653	protein targeting
SynMVIR181_00095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynMVIR181_00096	COG1088	dTDP-glucose 4,6-dehydratase activity
SynMVIR181_00099	COG1216	Glycosyl transferase, family 2
SynMVIR181_00099	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_00103	COG1045	serine acetyltransferase
SynMVIR181_00104	COG1725	Transcriptional regulator
SynMVIR181_00106	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynMVIR181_00107	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynMVIR181_00108	COG1372	Participates in initiation and elongation during chromosome replication
SynMVIR181_00108	COG0187	DNA topoisomerase II activity
SynMVIR181_00110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynMVIR181_00111	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynMVIR181_00112	COG0386	Belongs to the glutathione peroxidase family
SynMVIR181_00113	COG2239	Acts as a magnesium transporter
SynMVIR181_00114	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_00115	COG0596	Alpha beta hydrolase
SynMVIR181_00117	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynMVIR181_00119	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynMVIR181_00121	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SynMVIR181_00122	COG0802	atpase or kinase
SynMVIR181_00123	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynMVIR181_00125	COG0586	Pfam SNARE associated Golgi protein
SynMVIR181_00126	COG0629	single-stranded DNA binding
SynMVIR181_00128	COG1792	Involved in formation and maintenance of cell shape
SynMVIR181_00132	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynMVIR181_00136	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynMVIR181_00137	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynMVIR181_00138	COG0515	serine threonine protein kinase
SynMVIR181_00139	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynMVIR181_00140	COG2255	four-way junction helicase activity
SynMVIR181_00142	COG1473	amidohydrolase
SynMVIR181_00145	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynMVIR181_00146	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynMVIR181_00149	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SynMVIR181_00155	COG0463	Glycosyl transferase, family 2
SynMVIR181_00159	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynMVIR181_00160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynMVIR181_00161	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynMVIR181_00162	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_00163	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynMVIR181_00164	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynMVIR181_00165	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynMVIR181_00165	COG0662	Cupin 2, conserved barrel domain protein
SynMVIR181_00171	COG2337	Toxic component of a toxin-antitoxin (TA) module
SynMVIR181_00188	COG1487	ribonuclease activity
SynMVIR181_00194	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SynMVIR181_00198	COG0579	oxidoreductase
SynMVIR181_00200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynMVIR181_00201	COG0367	asparagine synthase
SynMVIR181_00206	COG2226	methyltransferase
SynMVIR181_00209	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynMVIR181_00209	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynMVIR181_00215	COG2244	polysaccharide biosynthetic process
SynMVIR181_00223	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SynMVIR181_00224	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SynMVIR181_00226	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_00230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SynMVIR181_00232	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynMVIR181_00234	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynMVIR181_00236	COG3273	potassium ion transport
SynMVIR181_00236	COG0471	metal ion transport
SynMVIR181_00239	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynMVIR181_00240	COG3273	potassium ion transport
SynMVIR181_00240	COG0471	metal ion transport
SynMVIR181_00241	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynMVIR181_00243	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynMVIR181_00245	COG0571	ribonuclease III activity
SynMVIR181_00255	COG1970	mechanosensitive ion channel activity
SynMVIR181_00258	COG0058	SHG alpha-glucan phosphorylase activity
SynMVIR181_00259	COG0475	glutathione-regulated potassium exporter activity
SynMVIR181_00263	COG0277	FAD linked oxidase domain protein
SynMVIR181_00265	COG0247	lactate metabolic process
SynMVIR181_00266	COG0538	isocitrate dehydrogenase activity
SynMVIR181_00270	COG5398	heme oxygenase
SynMVIR181_00272	COG1132	(ABC) transporter
SynMVIR181_00277	COG2192	nodulation
SynMVIR181_00280	COG0617	tRNA 3'-terminal CCA addition
SynMVIR181_00282	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynMVIR181_00283	COG0124	histidyl-tRNA synthetase
SynMVIR181_00284	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynMVIR181_00292	COG4447	cellulose binding
SynMVIR181_00293	COG1773	rubredoxin
SynMVIR181_00294	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_00295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_00296	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_00297	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynMVIR181_00298	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynMVIR181_00299	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SynMVIR181_00300	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynMVIR181_00300	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynMVIR181_00301	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SynMVIR181_00302	COG0494	nUDIX hydrolase
SynMVIR181_00303	COG0415	Belongs to the DNA photolyase family
SynMVIR181_00309	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynMVIR181_00310	COG3781	membrane
SynMVIR181_00311	COG0131	Imidazoleglycerol-phosphate dehydratase
SynMVIR181_00312	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynMVIR181_00315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynMVIR181_00319	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynMVIR181_00320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynMVIR181_00322	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynMVIR181_00323	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynMVIR181_00326	COG1253	flavin adenine dinucleotide binding
SynMVIR181_00331	COG0343	queuine tRNA-ribosyltransferase activity
SynMVIR181_00332	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynMVIR181_00338	COG0138	bifunctional purine biosynthesis protein purh
SynMVIR181_00341	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynMVIR181_00342	COG0004	ammonium transporteR
SynMVIR181_00343	COG1489	DNA binding
SynMVIR181_00344	COG0728	peptidoglycan biosynthetic process
SynMVIR181_00350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynMVIR181_00351	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynMVIR181_00352	COG1546	Belongs to the CinA family
SynMVIR181_00352	COG1058	Belongs to the CinA family
SynMVIR181_00353	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynMVIR181_00354	COG0066	3-isopropylmalate dehydratase activity
SynMVIR181_00361	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynMVIR181_00362	COG0193	aminoacyl-tRNA hydrolase activity
SynMVIR181_00365	COG4372	Transposase
SynMVIR181_00366	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynMVIR181_00367	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynMVIR181_00369	COG0717	Belongs to the dCTP deaminase family
SynMVIR181_00371	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynMVIR181_00376	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynMVIR181_00379	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynMVIR181_00383	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynMVIR181_00387	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynMVIR181_00390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynMVIR181_00392	COG2094	Belongs to the DNA glycosylase MPG family
SynMVIR181_00393	COG0540	Belongs to the ATCase OTCase family
SynMVIR181_00403	COG3536	Protein conserved in bacteria
SynMVIR181_00404	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynMVIR181_00406	COG0529	Catalyzes the synthesis of activated sulfate
SynMVIR181_00406	COG2046	Belongs to the sulfate adenylyltransferase family
SynMVIR181_00407	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynMVIR181_00408	COG0800	Aldolase
SynMVIR181_00410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynMVIR181_00412	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynMVIR181_00413	COG2226	methyltransferase
SynMVIR181_00415	COG4176	ABC-type proline glycine betaine transport system permease component
SynMVIR181_00416	COG2113	Glycine betaine
SynMVIR181_00417	COG0463	Glycosyl transferase, family 2
SynMVIR181_00418	COG0366	Alpha amylase catalytic
SynMVIR181_00425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynMVIR181_00427	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynMVIR181_00428	COG0436	Aminotransferase
SynMVIR181_00430	COG1530	ribonuclease E activity
SynMVIR181_00431	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynMVIR181_00433	COG0077	Prephenate dehydratase
SynMVIR181_00433	COG1605	Chorismate mutase
SynMVIR181_00434	COG2226	methyltransferase
SynMVIR181_00435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynMVIR181_00436	COG0051	transcription antitermination factor activity, RNA binding
SynMVIR181_00437	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynMVIR181_00438	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynMVIR181_00439	COG0049	tRNA binding
SynMVIR181_00440	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynMVIR181_00443	COG0067	glutamate synthase
SynMVIR181_00443	COG0070	glutamate synthase
SynMVIR181_00443	COG0069	glutamate synthase activity
SynMVIR181_00445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynMVIR181_00450	COG2885	chlorophyll binding
SynMVIR181_00451	COG2885	chlorophyll binding
SynMVIR181_00454	COG3239	Fatty acid desaturase
SynMVIR181_00460	COG0463	Glycosyl transferase, family 2
SynMVIR181_00465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynMVIR181_00467	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynMVIR181_00468	COG0254	rRNA binding
SynMVIR181_00469	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynMVIR181_00470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynMVIR181_00471	COG0101	tRNA pseudouridine synthase activity
SynMVIR181_00472	COG0203	ribosomal protein L17
SynMVIR181_00473	COG0202	RNA polymerase activity
SynMVIR181_00474	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynMVIR181_00475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynMVIR181_00476	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynMVIR181_00477	COG0563	adenylate kinase activity
SynMVIR181_00478	COG0201	protein transport
SynMVIR181_00479	COG0200	Binds to the 23S rRNA
SynMVIR181_00480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynMVIR181_00481	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynMVIR181_00482	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynMVIR181_00483	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynMVIR181_00484	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynMVIR181_00485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynMVIR181_00486	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynMVIR181_00487	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynMVIR181_00488	COG0255	Belongs to the universal ribosomal protein uL29 family
SynMVIR181_00489	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynMVIR181_00490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynMVIR181_00491	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynMVIR181_00492	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynMVIR181_00493	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynMVIR181_00494	COG0089	rRNA binding
SynMVIR181_00495	COG0088	Forms part of the polypeptide exit tunnel
SynMVIR181_00496	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynMVIR181_00499	COG3854	ATPases associated with a variety of cellular activities
SynMVIR181_00502	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynMVIR181_00506	COG0287	Prephenate dehydrogenase
SynMVIR181_00508	COG3001	Fructosamine kinase
SynMVIR181_00512	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynMVIR181_00513	COG1606	tRNA processing
SynMVIR181_00514	COG0076	glutamate decarboxylase activity
SynMVIR181_00515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynMVIR181_00516	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynMVIR181_00519	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynMVIR181_00520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynMVIR181_00521	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynMVIR181_00524	COG0772	Belongs to the SEDS family
SynMVIR181_00525	COG0489	protein tyrosine kinase activity
SynMVIR181_00526	COG0408	coproporphyrinogen oxidase activity
SynMVIR181_00536	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynMVIR181_00539	COG0656	L-ascorbic acid biosynthetic process
SynMVIR181_00541	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynMVIR181_00543	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynMVIR181_00544	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynMVIR181_00544	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynMVIR181_00545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynMVIR181_00573	COG0237	dephospho-CoA kinase activity
SynMVIR181_00577	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynMVIR181_00592	COG1070	Carbohydrate kinase
SynMVIR181_00593	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynMVIR181_00595	COG0539	negative regulation of cytoplasmic translation
SynMVIR181_00596	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynMVIR181_00601	COG0589	response to stress
SynMVIR181_00636	COG2890	protein-(glutamine-N5) methyltransferase activity
SynMVIR181_00637	COG0009	L-threonylcarbamoyladenylate synthase
SynMVIR181_00641	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynMVIR181_00642	COG2894	cell division
SynMVIR181_00643	COG0850	regulation of cytokinetic process
SynMVIR181_00644	COG1078	dGTPase activity
SynMVIR181_00645	COG0793	Belongs to the peptidase S41A family
SynMVIR181_00646	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynMVIR181_00647	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynMVIR181_00656	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynMVIR181_00660	COG3942	CHAP domain
SynMVIR181_00660	COG1388	LysM domain
SynMVIR181_00661	COG1012	belongs to the aldehyde dehydrogenase family
SynMVIR181_00663	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynMVIR181_00669	COG3852	Histidine kinase
SynMVIR181_00670	COG4565	transcriptional regulatory protein
SynMVIR181_00674	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynMVIR181_00685	COG2197	response regulator
SynMVIR181_00686	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynMVIR181_00690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynMVIR181_00692	COG1376	ErfK ybiS ycfS ynhG family protein
SynMVIR181_00693	COG1160	GTP binding
SynMVIR181_00694	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynMVIR181_00696	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynMVIR181_00697	COG1799	cell septum assembly
SynMVIR181_00698	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynMVIR181_00699	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_00701	COG1381	Involved in DNA repair and RecF pathway recombination
SynMVIR181_00702	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynMVIR181_00703	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynMVIR181_00704	COG0321	lipoyl(octanoyl) transferase activity
SynMVIR181_00705	COG1022	Amp-dependent synthetase and ligase
SynMVIR181_00707	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynMVIR181_00708	COG0531	amino acid
SynMVIR181_00709	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynMVIR181_00710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynMVIR181_00713	COG0626	cystathionine gamma-synthase activity
SynMVIR181_00715	COG4178	(ABC) transporter
SynMVIR181_00721	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SynMVIR181_00723	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SynMVIR181_00725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynMVIR181_00727	COG1104	cysteine desulfurase activity
SynMVIR181_00732	COG0657	acetylesterase activity
SynMVIR181_00734	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynMVIR181_00735	COG0579	oxidoreductase
SynMVIR181_00737	COG0481	GTPase activity
SynMVIR181_00750	COG5002	protein histidine kinase activity
SynMVIR181_00753	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynMVIR181_00757	COG3695	enzyme binding
SynMVIR181_00758	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynMVIR181_00758	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynMVIR181_00759	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynMVIR181_00760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynMVIR181_00762	COG0107	imidazoleglycerol-phosphate synthase activity
SynMVIR181_00764	COG2226	methyltransferase
SynMVIR181_00769	COG0752	glycyl-tRNA synthetase alpha subunit
SynMVIR181_00780	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynMVIR181_00781	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynMVIR181_00782	COG0740	serine-type endopeptidase activity
SynMVIR181_00783	COG0740	serine-type endopeptidase activity
SynMVIR181_00784	COG4956	integral membrane protein (PIN domain superfamily)
SynMVIR181_00785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynMVIR181_00786	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynMVIR181_00787	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynMVIR181_00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynMVIR181_00791	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynMVIR181_00792	COG4948	Mandelate Racemase Muconate Lactonizing
SynMVIR181_00797	COG0277	FAD linked oxidase domain protein
SynMVIR181_00799	COG0285	dihydrofolate synthase activity
SynMVIR181_00800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynMVIR181_00802	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynMVIR181_00805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynMVIR181_00806	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynMVIR181_00807	COG0134	indole-3-glycerol-phosphate synthase activity
SynMVIR181_00809	COG2274	protein secretion by the type I secretion system
SynMVIR181_00821	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynMVIR181_00822	COG0482	sulfurtransferase activity
SynMVIR181_00823	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynMVIR181_00823	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynMVIR181_00825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_00829	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynMVIR181_00830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynMVIR181_00832	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynMVIR181_00833	COG0228	four-way junction DNA binding
SynMVIR181_00834	COG1702	phosphate starvation-inducible protein PhoH
SynMVIR181_00838	COG3527	Alpha-acetolactate decarboxylase
SynMVIR181_00839	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynMVIR181_00841	COG0336	Belongs to the RNA methyltransferase TrmD family
SynMVIR181_00847	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynMVIR181_00849	COG1691	(AIR) carboxylase
SynMVIR181_00853	COG0352	thiamine-phosphate diphosphorylase activity
SynMVIR181_00855	COG0196	riboflavin kinase activity
SynMVIR181_00857	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynMVIR181_00858	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynMVIR181_00867	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynMVIR181_00870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynMVIR181_00871	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_00886	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynMVIR181_00888	COG1597	lipid kinase activity
SynMVIR181_00888	COG1803	Methylglyoxal synthase
SynMVIR181_00895	COG3119	arylsulfatase activity
SynMVIR181_00904	COG0477	Major facilitator Superfamily
SynMVIR181_00913	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynMVIR181_00913	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynMVIR181_00916	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynMVIR181_00917	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynMVIR181_00922	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynMVIR181_00929	COG1942	4-Oxalocrotonate Tautomerase
SynMVIR181_00942	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynMVIR181_00950	COG0477	Major facilitator Superfamily
SynMVIR181_00954	COG0432	Pfam Uncharacterised protein family UPF0047
SynMVIR181_00959	COG1492	cobalamin metabolic process
SynMVIR181_00961	COG0424	maF-like protein
SynMVIR181_00967	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynMVIR181_00968	COG0440	acetolactate synthase activity
SynMVIR181_00969	COG2267	carboxylic ester hydrolase activity
SynMVIR181_00974	COG2226	methyltransferase
SynMVIR181_00977	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynMVIR181_00978	COG0492	ferredoxin-NADP+ reductase activity
SynMVIR181_00988	COG3411	Ferredoxin
SynMVIR181_00989	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynMVIR181_00990	COG0733	neurotransmitter:sodium symporter activity
SynMVIR181_00993	COG0215	cysteine-tRNA ligase activity
SynMVIR181_00995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynMVIR181_00995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynMVIR181_00996	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynMVIR181_00997	COG0012	GTP binding
SynMVIR181_01005	COG0671	phosphoesterase, PA-phosphatase related
SynMVIR181_01013	COG0601	transmembrane transport
SynMVIR181_01014	COG4166	transmembrane transport
SynMVIR181_01017	COG0460	homoserine dehydrogenase
SynMVIR181_01018	COG2166	iron-sulfur cluster assembly
SynMVIR181_01020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynMVIR181_01041	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynMVIR181_01042	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynMVIR181_01045	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SynMVIR181_01046	COG2010	Cytochrome c
SynMVIR181_01047	COG0742	ribosomal rna small subunit methyltransferase
SynMVIR181_01048	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynMVIR181_01049	COG3118	belongs to the thioredoxin family
SynMVIR181_01050	COG0516	GMP reductase activity
SynMVIR181_01053	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynMVIR181_01054	COG0644	oxidoreductase
SynMVIR181_01057	COG1543	Belongs to the glycosyl hydrolase 57 family
SynMVIR181_01058	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynMVIR181_01059	COG0395	ABC-type sugar transport system, permease component
SynMVIR181_01064	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynMVIR181_01074	COG1480	7TM receptor with intracellular HD hydrolase
SynMVIR181_01075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynMVIR181_01076	COG0142	geranyltranstransferase activity
SynMVIR181_01087	COG0406	alpha-ribazole phosphatase activity
SynMVIR181_01088	COG1254	Belongs to the acylphosphatase family
SynMVIR181_01089	COG1797	cobyrinic acid a,c-diamide synthase activity
SynMVIR181_01090	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynMVIR181_01090	COG3409	Peptidoglycan-binding domain 1 protein
SynMVIR181_01091	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynMVIR181_01098	COG2205	protein histidine kinase activity
SynMVIR181_01101	COG0308	aminopeptidase N
SynMVIR181_01127	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynMVIR181_01148	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynMVIR181_01153	COG1640	4-alpha-glucanotransferase
SynMVIR181_01155	COG1187	pseudouridine synthase activity
SynMVIR181_01156	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_01158	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynMVIR181_01160	COG1982	Orn Lys Arg decarboxylase major
SynMVIR181_01161	COG0575	Belongs to the CDS family
SynMVIR181_01163	COG2267	carboxylic ester hydrolase activity
SynMVIR181_01164	COG0371	Dehydrogenase
SynMVIR181_01165	COG0542	response to heat
SynMVIR181_01166	COG0456	acetyltransferase
SynMVIR181_01167	COG0019	diaminopimelate decarboxylase activity
SynMVIR181_01168	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynMVIR181_01169	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynMVIR181_01170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynMVIR181_01171	COG1054	Belongs to the UPF0176 family
SynMVIR181_01174	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynMVIR181_01175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynMVIR181_01184	COG0589	response to stress
SynMVIR181_01184	COG0475	glutathione-regulated potassium exporter activity
SynMVIR181_01185	COG1132	(ABC) transporter
SynMVIR181_01187	COG0724	RNA recognition motif
SynMVIR181_01191	COG0513	Belongs to the DEAD box helicase family
SynMVIR181_01192	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynMVIR181_01192	COG0662	Cupin 2, conserved barrel domain protein
SynMVIR181_01193	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynMVIR181_01195	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynMVIR181_01196	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SynMVIR181_01234	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_01236	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SynMVIR181_01238	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynMVIR181_01245	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_01247	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynMVIR181_01248	COG0271	Belongs to the BolA IbaG family
SynMVIR181_01251	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynMVIR181_01261	COG0625	glutathione transferase activity
SynMVIR181_01266	COG0735	belongs to the Fur family
SynMVIR181_01268	COG1799	cell septum assembly
SynMVIR181_01276	COG0420	3'-5' exonuclease activity
SynMVIR181_01282	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynMVIR181_01287	COG1126	abc transporter atp-binding protein
SynMVIR181_01288	COG0765	amino acid transport
SynMVIR181_01290	COG4597	amino acid ABC transporter
SynMVIR181_01291	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynMVIR181_01293	COG0659	secondary active sulfate transmembrane transporter activity
SynMVIR181_01304	COG0799	negative regulation of ribosome biogenesis
SynMVIR181_01306	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynMVIR181_01308	COG1115	amino acid carrier protein
SynMVIR181_01310	COG1132	(ABC) transporter
SynMVIR181_01312	COG0149	triose-phosphate isomerase activity
SynMVIR181_01313	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynMVIR181_01315	COG1429	ligase activity, forming nitrogen-metal bonds
SynMVIR181_01316	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynMVIR181_01318	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynMVIR181_01319	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynMVIR181_01321	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynMVIR181_01353	COG0393	Putative heavy-metal-binding
SynMVIR181_01358	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_01362	COG0668	transmembrane transport
SynMVIR181_01363	COG4106	trans-aconitate 2-methyltransferase activity
SynMVIR181_01364	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynMVIR181_01367	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynMVIR181_01368	COG1122	ATPase activity
SynMVIR181_01370	COG0052	Belongs to the universal ribosomal protein uS2 family
SynMVIR181_01371	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynMVIR181_01373	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynMVIR181_01374	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynMVIR181_01375	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynMVIR181_01376	COG0751	glycine-tRNA ligase activity
SynMVIR181_01377	COG0644	oxidoreductase
SynMVIR181_01379	COG0826	peptidase U32
SynMVIR181_01382	COG1217	gtp-binding protein TYPA
SynMVIR181_01387	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynMVIR181_01388	COG0443	Heat shock 70 kDa protein
SynMVIR181_01398	COG0861	Integral membrane protein TerC family
SynMVIR181_01402	COG0513	Belongs to the DEAD box helicase family
SynMVIR181_01403	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynMVIR181_01405	COG0312	modulator of DNA gyrase
SynMVIR181_01406	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynMVIR181_01409	COG0163	prenyltransferase activity
SynMVIR181_01410	COG0557	exoribonuclease II activity
SynMVIR181_01412	COG2119	membrane
SynMVIR181_01416	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynMVIR181_01416	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynMVIR181_01420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynMVIR181_01421	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynMVIR181_01422	COG1615	UPF0182 protein
SynMVIR181_01426	COG0450	alkyl hydroperoxide reductase
SynMVIR181_01429	COG0739	heme binding
SynMVIR181_01430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynMVIR181_01441	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynMVIR181_01444	COG0557	exoribonuclease II activity
SynMVIR181_01445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynMVIR181_01446	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynMVIR181_01447	COG0072	phenylalanine-tRNA ligase activity
SynMVIR181_01447	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynMVIR181_01448	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynMVIR181_01457	COG2385	sporulation resulting in formation of a cellular spore
SynMVIR181_01463	COG0646	methionine synthase
SynMVIR181_01463	COG1410	methionine synthase
SynMVIR181_01464	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynMVIR181_01467	COG0613	PHP domain protein
SynMVIR181_01469	COG1981	membrane
SynMVIR181_01470	COG3046	protein related to deoxyribodipyrimidine photolyase
SynMVIR181_01472	COG0322	excinuclease ABC activity
SynMVIR181_01473	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynMVIR181_01478	COG1104	cysteine desulfurase activity
SynMVIR181_01479	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynMVIR181_01481	COG0495	leucyl-tRNA aminoacylation
SynMVIR181_01482	COG0166	Belongs to the GPI family
SynMVIR181_01487	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynMVIR181_01488	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynMVIR181_01489	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynMVIR181_01489	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynMVIR181_01490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynMVIR181_01491	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynMVIR181_01492	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynMVIR181_01494	COG0484	heat shock protein binding
SynMVIR181_01495	COG0443	Heat shock 70 kDa protein
SynMVIR181_01496	COG0573	inorganic phosphate transmembrane transporter activity
SynMVIR181_01497	COG0581	inorganic phosphate transmembrane transporter activity
SynMVIR181_01498	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynMVIR181_01501	COG0483	inositol monophosphate 1-phosphatase activity
SynMVIR181_01502	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynMVIR181_01505	COG0326	Molecular chaperone. Has ATPase activity
SynMVIR181_01506	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynMVIR181_01507	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynMVIR181_01508	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynMVIR181_01509	COG1653	transport
SynMVIR181_01512	COG3842	ATPase activity
SynMVIR181_01517	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynMVIR181_01518	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynMVIR181_01522	COG0469	pyruvate kinase activity
SynMVIR181_01523	COG1136	(ABC) transporter
SynMVIR181_01523	COG0577	efflux transmembrane transporter activity
SynMVIR181_01524	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynMVIR181_01525	COG0740	serine-type endopeptidase activity
SynMVIR181_01529	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynMVIR181_01530	COG2211	Major facilitator Superfamily
SynMVIR181_01537	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynMVIR181_01538	COG1175	transmembrane transport
SynMVIR181_01539	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynMVIR181_01545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SynMVIR181_01549	COG1793	dna ligase
SynMVIR181_01550	COG1201	RNA secondary structure unwinding
SynMVIR181_01563	COG0484	heat shock protein binding
SynMVIR181_01566	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynMVIR181_01567	COG1121	(ABC) transporter
SynMVIR181_01568	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynMVIR181_01570	COG3659	wide pore channel activity
SynMVIR181_01579	COG2226	methyltransferase
SynMVIR181_01580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynMVIR181_01594	COG2124	cytochrome p450
SynMVIR181_01595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SynMVIR181_01596	COG1611	Belongs to the LOG family
SynMVIR181_01621	COG0681	Belongs to the peptidase S26 family
SynMVIR181_01622	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynMVIR181_01624	COG1376	ErfK ybiS ycfS ynhG family protein
SynMVIR181_01625	COG0297	glycogen (starch) synthase activity
SynMVIR181_01627	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynMVIR181_01629	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynMVIR181_01636	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynMVIR181_01641	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynMVIR181_01643	COG3659	wide pore channel activity
SynMVIR181_01645	COG3128	pkhd-type hydroxylase
SynMVIR181_01646	COG1840	ABC-type Fe3 transport system, periplasmic component
SynMVIR181_01647	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynMVIR181_01648	COG2045	Belongs to the ComB family
SynMVIR181_01650	COG0860	N-Acetylmuramoyl-L-alanine amidase
SynMVIR181_01651	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynMVIR181_01652	COG0142	geranyltranstransferase activity
SynMVIR181_01653	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynMVIR181_01654	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynMVIR181_01657	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynMVIR181_01658	COG2176	DNA-directed DNA polymerase activity
SynMVIR181_01663	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynMVIR181_01665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynMVIR181_01666	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_01669	COG3659	wide pore channel activity
SynMVIR181_01672	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynMVIR181_01673	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynMVIR181_01677	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynMVIR181_01680	COG0174	glutamine synthetase
SynMVIR181_01689	COG2226	methyltransferase
SynMVIR181_01694	COG0515	serine threonine protein kinase
SynMVIR181_01695	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynMVIR181_01697	COG0628	permease
SynMVIR181_01699	COG0426	domain, Protein
SynMVIR181_01699	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynMVIR181_01701	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynMVIR181_01702	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynMVIR181_01703	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynMVIR181_01703	COG0022	dehydrogenase e1 component
SynMVIR181_01705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynMVIR181_01706	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynMVIR181_01707	COG0572	uridine kinase
SynMVIR181_01712	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynMVIR181_01717	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynMVIR181_01719	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynMVIR181_01726	COG0358	DNA primase activity
SynMVIR181_01744	COG0632	four-way junction helicase activity
SynMVIR181_01745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynMVIR181_01747	COG0587	DNA-directed DNA polymerase activity
SynMVIR181_01748	COG0154	amidase activity
SynMVIR181_01750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynMVIR181_01751	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynMVIR181_01752	COG1366	Belongs to the anti-sigma-factor antagonist family
SynMVIR181_01753	COG0505	Belongs to the CarA family
SynMVIR181_01754	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynMVIR181_01755	COG1132	(ABC) transporter
SynMVIR181_01757	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynMVIR181_01766	COG0612	Peptidase, M16
SynMVIR181_01770	COG1136	(ABC) transporter
SynMVIR181_01772	COG1216	Glycosyl transferase, family 2
SynMVIR181_01775	COG1836	PFAM Integral membrane protein DUF92
SynMVIR181_01776	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_01779	COG3639	organic phosphonate transmembrane transporter activity
SynMVIR181_01780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynMVIR181_01780	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynMVIR181_01781	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynMVIR181_01782	COG0436	Aminotransferase
SynMVIR181_01784	COG1573	uracil-dna glycosylase
SynMVIR181_01785	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynMVIR181_01786	COG0793	Belongs to the peptidase S41A family
SynMVIR181_01790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynMVIR181_01795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynMVIR181_01796	COG1494	fructose-1,6-bisphosphatase
SynMVIR181_01797	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynMVIR181_01799	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynMVIR181_01800	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynMVIR181_01801	COG0363	glucosamine-6-phosphate deaminase activity
SynMVIR181_01804	COG0129	dihydroxy-acid dehydratase activity
SynMVIR181_01806	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynMVIR181_01812	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynMVIR181_01813	COG0047	phosphoribosylformylglycinamidine synthase activity
SynMVIR181_01814	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynMVIR181_01815	COG0191	fructose-bisphosphate aldolase activity
SynMVIR181_01816	COG3588	fructose-bisphosphate aldolase
SynMVIR181_01817	COG0673	inositol 2-dehydrogenase activity
SynMVIR181_01819	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynMVIR181_01820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynMVIR181_01822	COG3954	Phosphoribulokinase
SynMVIR181_01823	COG0473	3-isopropylmalate dehydrogenase activity
SynMVIR181_01824	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynMVIR181_01825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynMVIR181_01828	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynMVIR181_01831	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynMVIR181_01832	COG2197	response regulator
SynMVIR181_01834	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynMVIR181_01836	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SynMVIR181_01837	COG0517	IMP dehydrogenase activity
SynMVIR181_01839	COG1376	ErfK ybiS ycfS ynhG family protein
SynMVIR181_01845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynMVIR181_01855	COG2010	Cytochrome c
SynMVIR181_01861	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynMVIR181_01863	COG1121	(ABC) transporter
SynMVIR181_01866	COG0701	Predicted permease
SynMVIR181_01867	COG2010	Cytochrome c
SynMVIR181_01872	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynMVIR181_01873	COG1121	(ABC) transporter
SynMVIR181_01889	COG2032	superoxide dismutase activity
SynMVIR181_01935	COG0300	oxidoreductase activity
SynMVIR181_01940	COG0730	response to heat
SynMVIR181_01948	COG2197	response regulator
SynMVIR181_01972	COG1064	alcohol dehydrogenase
SynMVIR181_01979	COG3781	membrane
SynMVIR181_01980	COG1012	belongs to the aldehyde dehydrogenase family
SynMVIR181_01996	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynMVIR181_01997	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynMVIR181_02012	COG0180	Tryptophanyl-tRNA synthetase
SynMVIR181_02016	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynMVIR181_02018	COG0837	glucose binding
SynMVIR181_02019	COG0083	homoserine kinase activity
SynMVIR181_02020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_02021	COG0339	signal peptide processing
SynMVIR181_02027	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynMVIR181_02028	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynMVIR181_02036	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynMVIR181_02037	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynMVIR181_02039	COG3794	PFAM blue (type 1) copper domain protein
SynMVIR181_02048	COG0542	response to heat
SynMVIR181_02050	COG1566	PFAM secretion protein HlyD family protein
SynMVIR181_02052	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynMVIR181_02052	COG0140	phosphoribosyl-ATP diphosphatase activity
SynMVIR181_02055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_02064	COG0159	tryptophan synthase activity
SynMVIR181_02068	COG0418	dihydroorotase activity
SynMVIR181_02069	COG0659	secondary active sulfate transmembrane transporter activity
SynMVIR181_02074	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynMVIR181_02075	COG1845	cytochrome c oxidase, subunit III
SynMVIR181_02077	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynMVIR181_02079	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynMVIR181_02080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynMVIR181_02083	COG0456	acetyltransferase
SynMVIR181_02085	COG1132	(ABC) transporter
SynMVIR181_02086	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynMVIR181_02087	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynMVIR181_02088	COG3842	ATPase activity
SynMVIR181_02089	COG0251	oxidation-reduction process
SynMVIR181_02096	COG0492	ferredoxin-NADP+ reductase activity
SynMVIR181_02104	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_02105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynMVIR181_02106	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynMVIR181_02111	COG4451	ribulose bisphosphate carboxylase, small
SynMVIR181_02112	COG1850	ribulose-bisphosphate carboxylase activity
SynMVIR181_02113	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynMVIR181_02115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynMVIR181_02116	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynMVIR181_02120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynMVIR181_02121	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynMVIR181_02122	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynMVIR181_02128	COG0730	response to heat
SynMVIR181_02129	COG0095	Lipoate-protein ligase
SynMVIR181_02131	COG0517	IMP dehydrogenase activity
SynMVIR181_02131	COG1994	Peptidase M50
SynMVIR181_02132	COG0135	phosphoribosylanthranilate isomerase activity
SynMVIR181_02134	COG0302	gtp cyclohydrolase
SynMVIR181_02136	COG0825	malonyl-CoA metabolic process
SynMVIR181_02137	COG5322	oxidoreductase activity
SynMVIR181_02138	COG3396	Phenylacetate-CoA oxygenase
SynMVIR181_02141	COG0539	negative regulation of cytoplasmic translation
SynMVIR181_02144	COG1496	oxidoreductase activity
SynMVIR181_02145	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynMVIR181_02149	COG0028	Belongs to the TPP enzyme family
SynMVIR181_02150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynMVIR181_02151	COG0582	viral genome integration into host DNA
SynMVIR181_02152	COG2226	methyltransferase
SynMVIR181_02154	COG0528	UMP kinase activity
SynMVIR181_02155	COG0233	cytoplasmic translational termination
SynMVIR181_02156	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynMVIR181_02157	COG0415	Belongs to the DNA photolyase family
SynMVIR181_02158	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynMVIR181_02159	COG0768	penicillin binding
SynMVIR181_02164	COG0681	Belongs to the peptidase S26 family
SynMVIR181_02168	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynMVIR181_02172	COG0442	prolyl-tRNA aminoacylation
SynMVIR181_02174	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynMVIR181_02176	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynMVIR181_02179	COG0629	single-stranded DNA binding
SynMVIR181_02182	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynMVIR181_02184	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynMVIR181_02187	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_02190	COG0181	hydroxymethylbilane synthase activity
SynMVIR181_02193	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynMVIR181_02194	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynMVIR181_02198	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynMVIR181_02199	COG0523	cobalamin synthesis protein
SynMVIR181_02205	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynMVIR181_02210	COG0708	Exodeoxyribonuclease III
SynMVIR181_02211	COG0277	FAD linked oxidase domain protein
SynMVIR181_02212	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynMVIR181_02215	COG0405	Gamma-glutamyltransferase
SynMVIR181_02217	COG1666	GTP binding
SynMVIR181_02229	COG2223	nitrite transmembrane transporter activity
SynMVIR181_02252	COG0217	transcriptional regulatory protein
SynMVIR181_02253	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynMVIR181_02254	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynMVIR181_02263	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynMVIR181_02264	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynMVIR181_02266	COG4251	negative regulation of phosphorylation
SynMVIR181_02267	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynMVIR181_02268	COG5002	protein histidine kinase activity
SynMVIR181_02269	COG0151	Belongs to the GarS family
SynMVIR181_02271	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynMVIR181_02273	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynMVIR181_02274	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynMVIR181_02275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynMVIR181_02277	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynMVIR181_02280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynMVIR181_02283	COG2197	response regulator
SynMVIR181_02285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynMVIR181_02287	COG3386	PFAM SMP-30 Gluconolaconase
SynMVIR181_02288	COG0284	orotidine-5'-phosphate decarboxylase activity
SynMVIR181_02289	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynMVIR181_02293	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynMVIR181_02294	COG2211	Major facilitator Superfamily
SynMVIR181_02298	COG0776	regulation of translation
SynMVIR181_02319	COG0857	belongs to the CobB CobQ family
SynMVIR181_02320	COG3000	fatty acid hydroxylase
SynMVIR181_02320	COG0300	oxidoreductase activity
SynMVIR181_02321	COG0024	Methionine aminopeptidase
SynMVIR181_02323	COG0335	large ribosomal subunit rRNA binding
SynMVIR181_02328	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynMVIR181_02333	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynMVIR181_02334	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynMVIR181_02337	COG0194	GDP metabolic process
SynMVIR181_02338	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SynMVIR181_02339	COG0805	protein transport
SynMVIR181_02341	COG0723	plastoquinol--plastocyanin reductase activity
SynMVIR181_02342	COG0739	heme binding
SynMVIR181_02347	COG0248	Ppx GppA phosphatase
SynMVIR181_02348	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynMVIR181_02349	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynMVIR181_02350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynMVIR181_02352	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynMVIR181_02353	COG1028	Short-chain dehydrogenase reductase Sdr
SynMVIR181_02355	COG0459	protein refolding
SynMVIR181_02357	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynMVIR181_02361	COG0109	protoheme IX farnesyltransferase activity
SynMVIR181_02362	COG1612	heme a metabolic process
SynMVIR181_02364	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynMVIR181_02365	COG1845	cytochrome c oxidase, subunit III
SynMVIR181_02372	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynMVIR181_02375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynMVIR181_02376	COG1007	ATP synthesis coupled electron transport
SynMVIR181_02377	COG1136	(ABC) transporter
SynMVIR181_02377	COG0577	efflux transmembrane transporter activity
SynMVIR181_02378	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_02379	COG0739	heme binding
SynMVIR181_02380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynMVIR181_02380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynMVIR181_02381	COG0436	Aminotransferase
SynMVIR181_02382	COG3118	belongs to the thioredoxin family
SynMVIR181_02383	COG1842	Phage shock protein A
SynMVIR181_02386	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_02387	COG0697	spore germination
SynMVIR181_02389	COG0616	signal peptide processing
SynMVIR181_02392	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynMVIR181_02393	COG0594	ribonuclease P activity
SynMVIR181_02396	COG0706	membrane insertase activity
SynMVIR181_02400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynMVIR181_02401	COG0750	zinc metalloprotease
SynMVIR181_02402	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynMVIR181_02404	COG1185	polyribonucleotide nucleotidyltransferase activity
SynMVIR181_02405	COG1218	3'(2'),5'-bisphosphate nucleotidase
SynMVIR181_02406	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynMVIR181_02411	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynMVIR181_02435	COG0363	glucosamine-6-phosphate deaminase activity
SynMVIR181_02436	COG2385	sporulation resulting in formation of a cellular spore
SynMVIR181_02437	COG1234	tRNA 3'-trailer cleavage
SynMVIR181_02438	COG2010	Cytochrome c
SynMVIR181_02443	COG2264	protein methyltransferase activity
SynMVIR181_02444	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynMVIR181_02448	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynMVIR181_02459	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynMVIR181_02460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SynMVIR181_02463	COG0459	protein refolding
SynMVIR181_02464	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynMVIR181_02465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynMVIR181_02466	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynMVIR181_02470	COG0387	Pfam Sodium calcium exchanger
SynMVIR181_02471	COG0006	proline dipeptidase activity
SynMVIR181_02472	COG1253	flavin adenine dinucleotide binding
SynMVIR181_02473	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynMVIR181_02475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynMVIR181_02475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynMVIR181_02476	COG0686	Belongs to the AlaDH PNT family
SynMVIR181_02479	COG3012	SEC-C Motif Domain Protein
SynMVIR181_02480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynMVIR181_02482	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynMVIR181_02484	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynMVIR181_02485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynMVIR181_02486	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynMVIR181_02487	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynMVIR181_02488	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynMVIR181_02489	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynMVIR181_02490	COG0356	it plays a direct role in the translocation of protons across the membrane
SynMVIR181_02492	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynMVIR181_02493	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynMVIR181_02498	COG0772	Belongs to the SEDS family
SynMVIR181_02500	COG1333	cytochrome c biogenesis protein
SynMVIR181_02501	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynMVIR181_02504	COG0347	Belongs to the P(II) protein family
SynMVIR181_02507	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynMVIR181_02508	COG0114	fumarate hydratase activity
SynMVIR181_02509	COG4581	dead DEAH box helicase
SynMVIR181_02510	COG0156	8-amino-7-oxononanoate synthase activity
SynMVIR181_02512	COG2226	methyltransferase
SynMVIR181_02513	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynMVIR181_02515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynMVIR181_02517	COG0484	heat shock protein binding
SynMVIR181_02518	COG0357	Ribosomal RNA small subunit methyltransferase G
SynMVIR181_02526	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynMVIR181_02529	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynMVIR181_02530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynMVIR181_02531	COG0085	RNA polymerase activity
SynMVIR181_02532	COG0084	hydrolase, TatD family'
SynMVIR181_02533	COG0268	Binds directly to 16S ribosomal RNA
SynMVIR181_02534	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynMVIR181_02535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynMVIR181_02536	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynMVIR181_02539	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynMVIR181_02539	COG2205	protein histidine kinase activity
SynMVIR181_02541	COG0641	radical SAM
SynMVIR181_02543	COG0779	Required for maturation of 30S ribosomal subunits
SynMVIR181_02544	COG0195	Participates in both transcription termination and antitermination
SynMVIR181_02546	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynMVIR181_02560	COG2988	succinylglutamate desuccinylase activity
SynMVIR181_02561	COG0435	Glutathione S-transferase
SynMVIR181_02563	COG0488	(ABC) transporter
SynMVIR181_02565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynMVIR181_02566	COG3842	ATPase activity
SynMVIR181_02567	COG1193	negative regulation of DNA recombination
SynMVIR181_02569	COG0113	porphobilinogen synthase activity
SynMVIR181_02570	COG0484	heat shock protein binding
SynMVIR181_02572	COG0659	secondary active sulfate transmembrane transporter activity
SynMVIR181_02637	COG0116	Belongs to the methyltransferase superfamily
SynMVIR181_02641	COG1196	nuclear chromosome segregation
SynMVIR181_02643	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynMVIR181_02646	COG0439	Biotin carboxylase
SynMVIR181_02649	COG0515	serine threonine protein kinase
SynMVIR181_02652	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynMVIR181_02653	COG4178	(ABC) transporter
SynMVIR181_02654	COG0537	adenosine 5'-monophosphoramidase activity
SynMVIR181_02657	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynMVIR181_02660	COG0242	peptide deformylase activity
SynMVIR181_02662	COG0235	Class ii aldolase
SynMVIR181_02663	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynMVIR181_02665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynMVIR181_02666	COG0719	Fe-S assembly protein
SynMVIR181_02667	COG0396	ATPase activity
SynMVIR181_02668	COG0719	Fe-S assembly protein
SynMVIR181_02669	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynMVIR181_02673	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynMVIR181_02677	COG2814	Major facilitator Superfamily
SynMVIR181_02679	COG0033	Phosphoglucomutase
SynMVIR181_02681	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynMVIR181_02687	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynMVIR181_02688	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynMVIR181_02689	COG0175	sulfate reduction
SynMVIR181_02690	COG1252	NADH dehydrogenase
SynMVIR181_02691	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynMVIR181_02692	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynMVIR181_02693	COG0569	domain protein
SynMVIR181_02694	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynMVIR181_02699	COG0488	(ABC) transporter
SynMVIR181_02701	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynMVIR181_02704	COG1643	Atp-dependent helicase
SynMVIR181_02707	COG1570	exodeoxyribonuclease VII activity
SynMVIR181_02717	COG0483	inositol monophosphate 1-phosphatase activity
SynMVIR181_02720	COG1968	undecaprenyl-diphosphatase activity
SynMVIR181_02722	COG1555	photosystem II stabilization
SynMVIR181_02723	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynMVIR181_02724	COG4243	Vitamin k epoxide reductase
SynMVIR181_02726	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynMVIR181_02729	COG1032	radical SAM domain protein
SynMVIR181_02739	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynMVIR181_02741	COG0457	Tetratricopeptide repeat
SynMVIR181_02741	COG0463	Glycosyl transferase, family 2
SynMVIR181_02742	COG1587	Uroporphyrinogen-III synthase
SynMVIR181_02745	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynMVIR181_02746	COG0316	Belongs to the HesB IscA family
SynMVIR181_02749	COG1090	epimerase
SynMVIR181_02752	COG0484	heat shock protein binding
SynMVIR181_02753	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynMVIR181_02754	COG3659	wide pore channel activity
SynMVIR181_02768	COG1122	ATPase activity
SynMVIR181_02772	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_02774	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynMVIR181_02775	COG2217	Heavy metal translocating P-type atpase
SynMVIR181_02777	COG3063	Type IV pilus biogenesis stability protein PilW
SynMVIR181_02778	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynMVIR181_02780	COG0416	fatty acid biosynthetic process
SynMVIR181_02781	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynMVIR181_02782	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynMVIR181_02785	COG1214	PFAM Peptidase M22, glycoprotease
SynMVIR181_02787	COG0617	tRNA 3'-terminal CCA addition
SynMVIR181_02789	COG1562	ergosterol biosynthetic process
SynMVIR181_02790	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynMVIR181_02790	COG0493	'glutamate synthase
SynMVIR181_02793	COG0583	DNA-binding transcription factor activity
SynMVIR181_02795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynMVIR181_02796	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_02799	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynMVIR181_02801	COG2197	response regulator
SynMVIR181_02804	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynMVIR181_02805	COG0713	ATP synthesis coupled electron transport
SynMVIR181_02806	COG0839	Belongs to the complex I subunit 6 family
SynMVIR181_02807	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynMVIR181_02808	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynMVIR181_02809	COG0372	Belongs to the citrate synthase family
SynMVIR181_02813	COG1420	regulation of RNA biosynthetic process
SynMVIR181_02815	COG0133	tryptophan synthase activity
SynMVIR181_02816	COG2226	methyltransferase
SynMVIR181_02817	COG0023	Translation Initiation Factor
SynMVIR181_02818	COG0529	Catalyzes the synthesis of activated sulfate
SynMVIR181_02819	COG0628	permease
SynMVIR181_02820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynMVIR181_02822	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynMVIR181_02823	COG0564	pseudouridine synthase activity
SynMVIR181_02824	COG0745	RESPONSE REGULATOR receiver
SynMVIR181_02826	COG1104	cysteine desulfurase activity
SynMVIR181_02829	COG0275	rRNA processing
SynMVIR181_02830	COG0649	NAD binding
SynMVIR181_02831	COG0824	Thioesterase
SynMVIR181_02833	COG4948	Mandelate Racemase Muconate Lactonizing
SynMVIR181_02834	COG1575	Belongs to the MenA family. Type 1 subfamily
SynMVIR181_02836	COG0189	ligase activity
SynMVIR181_02837	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynMVIR181_02838	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynMVIR181_02840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynMVIR181_02841	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynMVIR181_02844	COG0252	asparaginase activity
SynMVIR181_02845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynMVIR181_02846	COG0018	arginyl-trna synthetase
SynMVIR181_02847	COG0157	Belongs to the NadC ModD family
SynMVIR181_02848	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynMVIR181_02850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SynMVIR181_02851	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynMVIR181_02852	COG4172	Belongs to the ABC transporter superfamily
SynMVIR181_02854	COG0564	pseudouridine synthase activity
SynMVIR181_02856	COG0589	response to stress
SynMVIR181_02857	COG0126	phosphoglycerate kinase activity
SynMVIR181_02865	COG2084	Dehydrogenase
SynMVIR181_02867	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynMVIR181_02868	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynMVIR181_02874	COG0167	dihydroorotate dehydrogenase activity
SynMVIR181_02875	COG0328	RNA-DNA hybrid ribonuclease activity
SynMVIR181_02878	COG0222	ribosome binding
SynMVIR181_02879	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynMVIR181_02880	COG0081	regulation of translation
SynMVIR181_02881	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynMVIR181_02882	COG0250	Participates in transcription elongation, termination and antitermination
SynMVIR181_02883	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynMVIR181_02884	COG0542	response to heat
SynMVIR181_02885	COG0346	lactoylglutathione lyase activity
SynMVIR181_02886	COG0148	phosphopyruvate hydratase activity
SynMVIR181_02888	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynMVIR181_02891	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynMVIR181_02893	COG0237	dephospho-CoA kinase activity
SynMVIR181_02903	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynMVIR181_02906	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynMVIR181_02906	COG2022	thiamine diphosphate biosynthetic process
SynMVIR181_02907	COG0105	UTP biosynthetic process
SynMVIR181_02908	COG1166	arginine decarboxylase activity
SynMVIR181_02916	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynMVIR181_02918	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynMVIR181_02924	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SynMVIR181_02926	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SynMVIR181_02927	COG0426	domain, Protein
SynMVIR181_02927	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynMVIR181_02928	COG0426	domain, Protein
SynMVIR181_02928	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynMVIR181_02929	COG1773	rubredoxin
SynMVIR181_02931	COG1741	Belongs to the pirin family
SynMVIR181_02936	COG0509	glycine decarboxylation via glycine cleavage system
SynMVIR181_02937	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynMVIR181_02941	COG0359	binds to the 23S rRNA
SynMVIR181_02942	COG1372	Participates in initiation and elongation during chromosome replication
SynMVIR181_02942	COG0305	Participates in initiation and elongation during chromosome replication
SynMVIR181_02942	COG1372	Participates in initiation and elongation during chromosome replication
SynMVIR181_02942	COG0305	Participates in initiation and elongation during chromosome replication
SynMVIR181_02945	COG0445	tRNA wobble uridine modification
SynMVIR181_02956	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynMVIR181_02959	COG0398	Pfam SNARE associated Golgi protein
SynMVIR181_02964	COG1131	(ABC) transporter
SynMVIR181_02966	COG0668	transmembrane transport
SynMVIR181_02967	COG0525	valine-tRNA ligase activity
SynMVIR181_02970	COG3264	Mechanosensitive ion channel
SynMVIR181_02970	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynMVIR181_02971	COG0525	valine-tRNA ligase activity
SynMVIR181_02976	COG4221	oxidoreductase activity
SynMVIR181_02993	COG3956	TIGRFAM MazG family protein
SynMVIR181_02994	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynMVIR181_02995	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynMVIR181_02996	COG0010	Belongs to the arginase family
SynMVIR181_03000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynMVIR181_03001	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynMVIR181_03002	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_03005	COG0504	CTP synthase activity
SynMVIR181_03006	COG0602	queuosine metabolic process
SynMVIR181_03012	COG4574	serine-type endopeptidase inhibitor activity
SynMVIR181_03013	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynMVIR181_03016	COG0531	amino acid
SynMVIR181_03020	COG0559	Belongs to the binding-protein-dependent transport system permease family
SynMVIR181_03023	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynMVIR181_03024	COG0830	nickel cation binding
SynMVIR181_03025	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynMVIR181_03026	COG0829	nickel cation binding
SynMVIR181_03027	COG0831	urea catabolic process
SynMVIR181_03028	COG0832	Belongs to the urease beta subunit family
SynMVIR181_03029	COG0804	urea catabolic process
SynMVIR181_03032	COG2308	Evidence 4 Homologs of previously reported genes of
SynMVIR181_03037	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynMVIR181_03040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynMVIR181_03042	COG2116	formate transmembrane transporter activity
SynMVIR181_03044	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynMVIR181_03046	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynMVIR181_03048	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynMVIR181_03049	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynMVIR181_03050	COG0170	dolichyl monophosphate biosynthetic process
SynMVIR181_03051	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynMVIR181_03053	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynMVIR181_03055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynMVIR181_03057	COG0788	formyltetrahydrofolate deformylase activity
SynMVIR181_03059	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynMVIR181_03061	COG0443	Heat shock 70 kDa protein
SynMVIR181_03062	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynMVIR181_03064	COG0360	Binds together with S18 to 16S ribosomal RNA
SynMVIR181_03066	COG0137	argininosuccinate synthase activity
SynMVIR181_03069	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynMVIR181_03073	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynMVIR181_03074	COG0438	transferase activity, transferring glycosyl groups
SynMVIR181_03077	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynMVIR181_03078	COG0497	DNA recombination
SynMVIR181_03079	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynMVIR181_03081	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine