locus-tag	class	description
NIES970_00010	ENOG4105BZ1	(ABC) transporter
NIES970_00020	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
NIES970_00050	ENOG4105EPC	oxidoreductase
NIES970_00070	ENOG410811Q	Ferredoxin
NIES970_00080	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
NIES970_00120	ENOG4107CUI	carotenoid binding protein
NIES970_00140	ENOG4105KZX	Pterin carbinolamine dehydratase
NIES970_00150	ENOG4108PWY	Carbohydrate-selective porin OprB
NIES970_00160	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
NIES970_00200	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
NIES970_00210	ENOG4107RFW	hydrolase family 57
NIES970_00240	ENOG4108IV0	ABC, transporter
NIES970_00260	ENOG4105CE4	GlcNAc 6-P deacetylase
NIES970_00330	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
NIES970_00340	ENOG4105E0X	reductase
NIES970_00370	ENOG4108IQE	Amp-dependent synthetase and ligase
NIES970_00400	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
NIES970_00420	ENOG4105CQM	Urea amidohydrolase subunit alpha
NIES970_00450	ENOG4107QIZ	NADH dehydrogenase
NIES970_00520	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
NIES970_00570	ENOG4105CQS	hydrogenase expression formation protein HypD
NIES970_00600	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
NIES970_00640	ENOG4105DUM	transcriptional regulator, lysR family
NIES970_00650	ENOG4105D65	subunit l
NIES970_00660	ENOG4105C8S	subunit m
NIES970_00690	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
NIES970_00700	ENOG4105C5R	Aminotransferase
NIES970_00710	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
NIES970_00770	ENOG4105C01	Dihydroxy-acid dehydratase
NIES970_00800	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
NIES970_00850	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
NIES970_00880	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
NIES970_00910	ENOG4105DFU	Cell wall formation (By similarity)
NIES970_00920	ENOG4105D4A	Cell wall formation (By similarity)
NIES970_00930	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
NIES970_00960	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
NIES970_00970	ENOG4105C8B	TIGR00159 family
NIES970_00990	ENOG4105SUU	thioesterase domain
NIES970_01010	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
NIES970_01020	ENOG41065W4	chlorophyll a b binding light harvesting protein
NIES970_01040	ENOG4105CGK	Exodeoxyribonuclease III
NIES970_01140	ENOG4105CBT	Fructose-1,6-bisphosphatase
NIES970_01150	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
NIES970_01170	ENOG4108Z03	MAF-like protein
NIES970_01210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_01230	ENOG4105DHP	deoxycytidine triphosphate deaminase
NIES970_01250	ENOG4105MSA	Photosystem II reaction center W protein
NIES970_01260	ENOG4107R3J	Transporter
NIES970_01280	ENOG4105CJW	magnesium transporter
NIES970_01330	ENOG4108YZ9	Urea amidohydrolase subunit gamma
NIES970_01360	ENOG4105XEV	csbD-like
NIES970_01380	ENOG4105XEV	csbD-like
NIES970_01450	ENOG4105C19	ABC transporter
NIES970_01460	ENOG41080ZE	Adenylate cyclase
NIES970_01480	ENOG4105KHC	sulfurtransferase
NIES970_01490	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_01500	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
NIES970_01520	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
NIES970_01550	ENOG4105BZU	Histidine kinase
NIES970_01570	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
NIES970_01580	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
NIES970_01680	ENOG4105CGH	5'-nucleotidase
NIES970_01710	ENOG4105VUV	UPF0367 protein
NIES970_01730	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
NIES970_01760	ENOG4105BZU	Histidine kinase
NIES970_01770	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
NIES970_01780	ENOG4105F23	Fibronectin-binding protein
NIES970_01800	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
NIES970_01830	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NIES970_01850	ENOG4105ETX	regulatoR
NIES970_01860	ENOG4108JQC	penicillin-binding protein 1A
NIES970_01880	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
NIES970_01890	ENOG4105ZDH	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
NIES970_01940	ENOG4108RTU	Aldolase
NIES970_01970	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
NIES970_01980	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
NIES970_02010	ENOG4108JQ6	ABC transporter
NIES970_02060	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
NIES970_02070	ENOG4107SC1	transglycosylase
NIES970_02190	ENOG4108IV0	ABC, transporter
NIES970_02200	ENOG4105C0Z	ABC transporter
NIES970_02220	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
NIES970_02250	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
NIES970_02270	ENOG4108UNF	response regulator
NIES970_02280	ENOG4108ZGA	chew protein
NIES970_02300	ENOG4105CBS	Chea signal transduction histidine kinase
NIES970_02310	ENOG4105DVC	DnaJ domain protein
NIES970_02330	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
NIES970_02350	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
NIES970_02390	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
NIES970_02440	ENOG4105C7Z	Conserved Protein
NIES970_02460	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
NIES970_02480	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
NIES970_02500	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
NIES970_02520	ENOG4105C75	arginyL-tRNA synthetase
NIES970_02540	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
NIES970_02600	ENOG4105C37	(CBS) domain
NIES970_02640	ENOG4105DGW	oligopeptidase A
NIES970_02680	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
NIES970_02700	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
NIES970_02730	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
NIES970_02740	ENOG4105C32	Amino acid ABC transporter (Permease)
NIES970_02750	ENOG4105C32	Amino acid ABC transporter (Permease)
NIES970_02760	ENOG4105C0Z	ABC transporter
NIES970_02780	ENOG4105DEF	Extracellular solute-binding protein, family 5
NIES970_02800	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
NIES970_02810	ENOG41072GX	Peptidase M22 Glycoprotease
NIES970_02840	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
NIES970_02880	ENOG41082AN	stage II sporulation protein
NIES970_02890	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NIES970_02930	ENOG4105IJJ	transcriptional regulator, crp fnr family
NIES970_02950	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
NIES970_02960	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
NIES970_03000	ENOG4105BZU	Histidine kinase
NIES970_03020	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
NIES970_03040	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NIES970_03120	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
NIES970_03180	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
NIES970_03190	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
NIES970_03250	ENOG41084GG	50S ribosomal protein L33
NIES970_03280	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
NIES970_03330	ENOG4105ECY	inositol monophosphatase
NIES970_03410	ENOG4105CZX	twitching motility protein
NIES970_03420	ENOG4107QHF	type ii secretion system protein e
NIES970_03430	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIES970_03440	ENOG4105CFG	Acts as a chaperone (By similarity)
NIES970_03470	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
NIES970_03480	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
NIES970_03510	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
NIES970_03560	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
NIES970_03590	ENOG4105C1V	Peptidase, M16
NIES970_03620	ENOG4105EYW	Ion transport protein
NIES970_03670	ENOG4105D17	glycoside hydrolase, family 3 domain protein
NIES970_03680	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
NIES970_03690	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
NIES970_03700	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
NIES970_03710	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
NIES970_03720	ENOG4108KVB	repeat protein
NIES970_03750	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
NIES970_03760	ENOG4105YES	addiction module antidote protein
NIES970_03780	ENOG4105C9M	aspartyl-trna synthetase
NIES970_03790	ENOG4105D3R	alkyl hydroperoxide reductase
NIES970_03800	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
NIES970_03860	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NIES970_03890	ENOG4107QJE	Chromosome Partitioning Protein
NIES970_03910	ENOG41080FP	Hydrolase
NIES970_03920	ENOG4105D3Q	Sugar transferase
NIES970_03930	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
NIES970_04000	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
NIES970_04010	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
NIES970_04110	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
NIES970_04130	ENOG4108K7V	UPF0284 protein
NIES970_04140	ENOG410848W	30S ribosomal protein S21
NIES970_04150	ENOG4107PU6	Membrane
NIES970_04160	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NIES970_04170	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
NIES970_04190	ENOG4108JJB	ABC transporter
NIES970_04200	ENOG4107Y82	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
NIES970_04210	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
NIES970_04240	ENOG4105DHJ	ABC, transporter
NIES970_04300	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
NIES970_04330	ENOG4105E2X	shikimate dehydrogenase
NIES970_04350	ENOG4105C3G	gtp-binding protein
NIES970_04370	ENOG4108MXF	Alpha Beta Hydrolase
NIES970_04420	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
NIES970_04430	ENOG4107T8Q	Glycosyl transferase (Group 1
NIES970_04440	ENOG4105BZ1	(ABC) transporter
NIES970_04490	ENOG4105FFC	UPF0187 protein
NIES970_04520	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
NIES970_04530	ENOG4108YZT	Adenosylcobinamide kinase
NIES970_04540	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
NIES970_04550	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
NIES970_04560	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
NIES970_04570	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
NIES970_04600	ENOG4105ERG	peptidase m48, ste24p
NIES970_04620	ENOG4105ESV	Glycosyl transferase, family 4
NIES970_04630	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
NIES970_04760	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
NIES970_04770	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
NIES970_04790	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
NIES970_04800	ENOG4105D7N	magnesium and cobalt transport protein CorA
NIES970_04820	ENOG4105D52	delta-aminolevulinic acid dehydratase
NIES970_04850	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
NIES970_04910	ENOG4107T8T	UPF0173 metal-dependent hydrolase
NIES970_04920	ENOG4105DDQ	anthranilate synthase
NIES970_04940	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
NIES970_04960	ENOG4105ECK	Fatty Acid Desaturase
NIES970_04970	ENOG4105CMR	udp-glucose 4-epimerase
NIES970_05060	ENOG4105CH7	arginosuccinase
NIES970_05070	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
NIES970_05080	ENOG4108NGH	radical SAM domain protein
NIES970_05110	ENOG4105CH7	arginosuccinase
NIES970_05210	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
NIES970_05220	ENOG4105CBX	hi0933 family
NIES970_05270	ENOG4108MGF	sugar kinase
NIES970_05280	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
NIES970_05290	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
NIES970_05320	ENOG4105BZU	Histidine kinase
NIES970_05330	ENOG4105BZU	Histidine kinase
NIES970_05420	ENOG4105BZU	Histidine kinase
NIES970_05470	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
NIES970_05510	ENOG4105C5S	asparaginyl-tRNA synthetase
NIES970_05550	ENOG4108Z0R	Transferase
NIES970_05580	ENOG4105DIK	(ABC) transporter
NIES970_05590	ENOG4105DSE	periplasmic solute binding protein
NIES970_05610	ENOG41067UF	
NIES970_05630	ENOG4105EYH	Exonuclease
NIES970_05650	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
NIES970_05700	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
NIES970_05710	ENOG4105CQR	helicase
NIES970_05720	ENOG4105BZU	Histidine kinase
NIES970_05750	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
NIES970_05840	ENOG4108HYG	acetyltransferase
NIES970_05930	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NIES970_05970	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
NIES970_05980	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NIES970_06060	ENOG4105KI2	Urea amidohydrolase subunit beta
NIES970_06070	ENOG4105DKQ	ROK family
NIES970_06080	ENOG4105M4P	Tetr family transcriptional regulator
NIES970_06090	ENOG4105HFZ	Membrane
NIES970_06100	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
NIES970_06120	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NIES970_06150	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
NIES970_06160	ENOG4105E89	ABC transporter
NIES970_06210	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
NIES970_06240	ENOG4105BZU	Histidine kinase
NIES970_06270	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
NIES970_06310	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_06330	ENOG4105W5Q	DNA repair protein (RadC
NIES970_06350	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
NIES970_06390	ENOG4107VEG	TrkA-N domain protein
NIES970_06410	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
NIES970_06420	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
NIES970_06430	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
NIES970_06440	ENOG4106AY4	Required for PSII activity (By similarity)
NIES970_06450	ENOG4106DN3	This protein is a component of the reaction center of photosystem II (By similarity)
NIES970_06470	ENOG4105JKW	Valine--pyruvate aminotransferase
NIES970_06480	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
NIES970_06510	ENOG4105CJ1	ABC, transporter
NIES970_06560	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
NIES970_06620	ENOG4105CP7	Triose-phosphate isomerase
NIES970_06650	ENOG4105DZP	Membrane-associated zinc metalloprotease
NIES970_06670	ENOG41085FC	arsR family transcriptional regulator
NIES970_06710	ENOG4105BZS	acriflavin resistance protein
NIES970_06770	ENOG4107T9Q	phosphonate abc transporter
NIES970_06810	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
NIES970_06820	ENOG4105CAT	Cytidine monophosphate kinase
NIES970_06840	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
NIES970_06860	ENOG4105C2X	Arabinose 5-phosphate isomerase
NIES970_06880	ENOG4105WIA	photosystem II reaction center protein H
NIES970_06890	ENOG410686T	photosystem II reaction center protein N
NIES970_06910	ENOG4106BTU	phycobilisome rod-core linker polypeptide
NIES970_06930	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
NIES970_06970	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
NIES970_06980	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
NIES970_07010	ENOG4105BZ1	(ABC) transporter
NIES970_07030	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
NIES970_07040	ENOG4105D44	asparaginase
NIES970_07120	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
NIES970_07140	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
NIES970_07170	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
NIES970_07210	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
NIES970_07220	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
NIES970_07230	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
NIES970_07240	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NIES970_07250	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NIES970_07260	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NIES970_07270	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NIES970_07280	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
NIES970_07290	ENOG4105PA3	atp synthase
NIES970_07330	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
NIES970_07380	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
NIES970_07390	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
NIES970_07400	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
NIES970_07410	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
NIES970_07420	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
NIES970_07430	ENOG4105CHV	Transcription elongation factor NusA
NIES970_07450	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
NIES970_07460	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
NIES970_07470	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
NIES970_07490	ENOG4105S7S	phosphonate abc transporter
NIES970_07500	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
NIES970_07550	ENOG4105C5H	ABC transporter
NIES970_07600	ENOG4108IUZ	ABC transporter
NIES970_07620	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
NIES970_07710	ENOG4105BZU	Histidine kinase
NIES970_07720	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
NIES970_07760	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
NIES970_07780	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
NIES970_07790	ENOG4107EEY	synthase
NIES970_07810	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
NIES970_07820	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
NIES970_07830	ENOG4105D8X	mechanosensitive ion channel
NIES970_07840	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
NIES970_07870	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
NIES970_07900	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
NIES970_07940	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
NIES970_08020	ENOG4108DJF	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
NIES970_08030	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
NIES970_08050	ENOG4105C0D	helicase
NIES970_08060	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
NIES970_08110	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
NIES970_08120	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
NIES970_08130	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
NIES970_08140	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NIES970_08180	ENOG4105C5H	ABC transporter
NIES970_08250	ENOG4108PWY	Carbohydrate-selective porin OprB
NIES970_08280	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
NIES970_08290	ENOG4105C3J	Cysteine desulfurase
NIES970_08310	ENOG4105DXN	mazG family
NIES970_08360	ENOG4105C5H	ABC transporter
NIES970_08430	ENOG4108PWY	Carbohydrate-selective porin OprB
NIES970_08460	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
NIES970_08470	ENOG4105C3J	Cysteine desulfurase
NIES970_08490	ENOG4105DXN	mazG family
NIES970_08570	ENOG4107Z6A	sulfate abc transporter permease
NIES970_08610	ENOG4107QVP	Dehydrogenase
NIES970_08640	ENOG4105MS2	ribosomal subunit Interface protein
NIES970_08650	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
NIES970_08660	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIES970_08670	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
NIES970_08680	ENOG4105CHR	reductase
NIES970_08690	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
NIES970_08710	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
NIES970_08760	ENOG4107QPR	SAICAR synthetase
NIES970_08770	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIES970_08780	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NIES970_08790	ENOG4105D5T	phosphonate abc transporter
NIES970_08800	ENOG4105BZ1	(ABC) transporter
NIES970_08820	ENOG4105CQB	FAD linked oxidase domain protein
NIES970_08880	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
NIES970_08920	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
NIES970_08970	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
NIES970_09030	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
NIES970_09080	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
NIES970_09110	ENOG4108UHE	carbonic anhydrase
NIES970_09140	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
NIES970_09160	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
NIES970_09170	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
NIES970_09180	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
NIES970_09190	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIES970_09200	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
NIES970_09210	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
NIES970_09220	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
NIES970_09230	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
NIES970_09240	ENOG410848H	50s ribosomal protein l29
NIES970_09250	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
NIES970_09260	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
NIES970_09270	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
NIES970_09280	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIES970_09290	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
NIES970_09300	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
NIES970_09310	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
NIES970_09320	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
NIES970_09330	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
NIES970_09350	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
NIES970_09370	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIES970_09380	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
NIES970_09400	ENOG4108ZT0	50S ribosomal protein l17
NIES970_09410	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
NIES970_09420	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
NIES970_09430	ENOG4108UJD	30S ribosomal protein S9
NIES970_09440	ENOG41082HT	Binds the 23S rRNA (By similarity)
NIES970_09450	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
NIES970_09480	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
NIES970_09520	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
NIES970_09530	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
NIES970_09550	ENOG4107Z3D	50S ribosomal protein l10
NIES970_09560	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
NIES970_09570	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
NIES970_09580	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
NIES970_09600	ENOG4105CV1	Transketolase (EC 2.2.1.1)
NIES970_09640	ENOG4105CTK	cobaltochelatase, cobn subunit
NIES970_09720	ENOG4105EHU	Circadian clock protein KaiC
NIES970_09730	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
NIES970_09740	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
NIES970_09750	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
NIES970_09770	ENOG4105CHM	Aminotransferase
NIES970_09800	ENOG4105BZU	Histidine kinase
NIES970_09810	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
NIES970_09860	ENOG4108IYU	L-aspartate oxidase
NIES970_09910	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NIES970_09940	ENOG4105BZU	Histidine kinase
NIES970_09960	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NIES970_09970	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
NIES970_09990	ENOG4108KMV	Glycosyl transferase (Group 1
NIES970_10010	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
NIES970_10030	ENOG4105BZU	Histidine kinase
NIES970_10050	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
NIES970_10100	ENOG41082ZZ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
NIES970_10110	ENOG4107ETG	50S ribosomal protein L34
NIES970_10140	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NIES970_10150	ENOG4105W8H	transhydrogenase (subunit alpha
NIES970_10160	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NIES970_10190	ENOG4106E83	A core subunit of photosystem II (PSII) (By similarity)
NIES970_10200	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
NIES970_10210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_10250	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
NIES970_10260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_10280	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
NIES970_10290	ENOG4105K46	50S ribosomal protein l27
NIES970_10300	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
NIES970_10330	ENOG4105CVN	desaturase
NIES970_10370	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
NIES970_10380	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
NIES970_10430	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
NIES970_10440	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
NIES970_10450	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
NIES970_10480	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
NIES970_10500	ENOG41060PQ	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
NIES970_10520	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
NIES970_10570	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NIES970_10630	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
NIES970_10640	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
NIES970_10650	ENOG4105DB7	PHP domain protein
NIES970_10670	ENOG4105D0M	Protease HtpX homolog
NIES970_10700	ENOG4105C1V	Peptidase, M16
NIES970_10710	ENOG4105CFG	Acts as a chaperone (By similarity)
NIES970_10720	ENOG4105DX0	Hemolysin A
NIES970_10760	ENOG4107WDG	serine threonine protein kinase
NIES970_10770	ENOG4107S5T	Carbohydrate kinase
NIES970_10790	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
NIES970_10820	ENOG4108ZF3	Phosphatase
NIES970_10830	ENOG4105DSB	aldose 1-epimerase
NIES970_10850	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
NIES970_10890	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
NIES970_10930	ENOG4105CEY	Amp-dependent synthetase and ligase
NIES970_10960	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
NIES970_10980	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
NIES970_11020	ENOG4106F7P	Seems to play a role in the dimerization of PSII (By similarity)
NIES970_11030	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
NIES970_11070	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
NIES970_11130	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
NIES970_11150	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
NIES970_11160	ENOG4106FN3	tellurium resistance protein
NIES970_11210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_11230	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
NIES970_11270	ENOG4105Q36	FHA domain containing protein
NIES970_11280	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
NIES970_11290	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NIES970_11340	ENOG4107QI6	Cysteine desulfurase
NIES970_11350	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
NIES970_11360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
NIES970_11440	ENOG4105C26	Dehydrogenase
NIES970_11450	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
NIES970_11470	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
NIES970_11550	ENOG4105CJW	magnesium transporter
NIES970_11560	ENOG4105VFU	Rna-binding protein
NIES970_11570	ENOG4105CIK	Amidinotransferase
NIES970_11590	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NIES970_11600	ENOG4105CPJ	photosystem II manganese-stabilizing
NIES970_11610	ENOG4108IPT	Naphthoate synthase
NIES970_11630	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_11640	ENOG4105G5N	sensor protein
NIES970_11650	ENOG4107SC0	ferredoxin--NADP reductase
NIES970_11660	ENOG4105D65	subunit l
NIES970_11690	ENOG4105DZ0	fad dependent oxidoreductase
NIES970_11720	ENOG4105BZU	Histidine kinase
NIES970_11730	ENOG4107QPD	alcohol dehydrogenase
NIES970_11740	ENOG4105C4W	S-formylglutathione hydrolase
NIES970_11750	ENOG4107WDG	serine threonine protein kinase
NIES970_11810	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
NIES970_11850	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
NIES970_11860	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
NIES970_11870	ENOG41085RW	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
NIES970_11880	ENOG4105CXT	aspartate transcarbamylase
NIES970_11890	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
NIES970_11900	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
NIES970_11910	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
NIES970_11940	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
NIES970_11960	ENOG4107WJM	-acetyltransferase
NIES970_11970	ENOG4105BZU	Histidine kinase
NIES970_11980	ENOG41086B8	CoB-CoM heterodisulfide reductase
NIES970_12000	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
NIES970_12010	ENOG4105E9K	Isocitrate dehydrogenase
NIES970_12030	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
NIES970_12040	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
NIES970_12050	ENOG4105CN1	protease
NIES970_12070	ENOG41083EU	50s ribosomal protein l28
NIES970_12100	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
NIES970_12130	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
NIES970_12150	ENOG4105F2W	methyltransferase
NIES970_12190	ENOG4105QVC	MOSC domain-containing protein
NIES970_12200	ENOG4108IAB	Phoh family
NIES970_12250	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
NIES970_12280	ENOG4107TVC	Glycosyl transferase, family 2
NIES970_12300	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
NIES970_12320	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
NIES970_12370	ENOG4105D7V	transposase
NIES970_12380	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
NIES970_12390	ENOG4105E4F	Isochorismate synthase
NIES970_12400	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
NIES970_12430	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
NIES970_12450	ENOG4107RAQ	aminopeptidase
NIES970_12460	ENOG4108JYK	Dehydrogenase
NIES970_12470	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NIES970_12490	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
NIES970_12520	ENOG4105C0P	Mg chelatase subunit ChlI
NIES970_12540	ENOG4108KGH	TRANSCRIPTIONal
NIES970_12560	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NIES970_12600	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NIES970_12630	ENOG4107SGM	protein serine threonine phosphatase
NIES970_12640	ENOG4107R51	Glycosyl transferase, family 2
NIES970_12650	ENOG4105BZ4	penicillin-binding protein
NIES970_12660	ENOG4108807	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
NIES970_12710	ENOG4105C1J	atp-dependent rna helicase
NIES970_12740	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
NIES970_12780	ENOG4105CFP	Peptidase U32
NIES970_12830	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
NIES970_12840	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
NIES970_12850	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
NIES970_12860	ENOG4105K63	Thioredoxin
NIES970_12900	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
NIES970_12930	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NIES970_12940	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
NIES970_12970	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
NIES970_13010	ENOG4105C37	(CBS) domain
NIES970_13030	ENOG4105CZX	twitching motility protein
NIES970_13050	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
NIES970_13290	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
NIES970_13370	ENOG4105C89	phosphohexose isomerase
NIES970_13450	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
NIES970_13480	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
NIES970_13520	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
NIES970_13540	ENOG41082B1	30S ribosomal protein S16
NIES970_13610	ENOG4105CVB	Vitamin K epoxide reductase
NIES970_13650	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
NIES970_13670	ENOG4105YB8	TM2 domain containing protein
NIES970_13690	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
NIES970_13700	ENOG4105CDA	abc transporter atp-binding protein
NIES970_13780	ENOG4105DRS	transport system, permease
NIES970_13810	ENOG4105MSA	Photosystem II reaction center W protein
NIES970_13820	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NIES970_13840	ENOG4105BZU	Histidine kinase
NIES970_13920	ENOG4105E66	phosphoriboisomerase A
NIES970_13930	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
NIES970_13940	ENOG4105CDU	Replicative dna helicase
NIES970_13940	ENOG4105CDU	Replicative dna helicase
NIES970_13970	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
NIES970_13990	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
NIES970_14060	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
NIES970_14070	ENOG4105D7Z	glutathione synthase
NIES970_14080	ENOG4105D49	3-dehydroquinate synthase
NIES970_14100	ENOG4107RDB	Major Facilitator
NIES970_14120	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
NIES970_14130	ENOG4107RJ1	sodium solute
NIES970_14140	ENOG4105C09	Bile acid
NIES970_14160	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
NIES970_14250	ENOG4105M0M	Tetracycline resistance protein
NIES970_14290	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
NIES970_14340	ENOG4106MP8	UPF0754 membrane protein
NIES970_14350	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
NIES970_14370	ENOG4105BZU	Histidine kinase
NIES970_14380	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NIES970_14400	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIES970_14440	ENOG4105CBS	Chea signal transduction histidine kinase
NIES970_14460	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
NIES970_14490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NIES970_14500	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
NIES970_14550	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
NIES970_14570	ENOG4105BZU	Histidine kinase
NIES970_14580	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
NIES970_14600	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
NIES970_14630	ENOG4105DK0	Indole-3-glycerol phosphate synthase
NIES970_14670	ENOG4107RIQ	Sulfate adenylate transferase
NIES970_14810	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
NIES970_14840	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIES970_14860	ENOG41084GC	stage II sporulation protein
NIES970_14890	ENOG4108YZA	Nitrogen regulatory protein pii
NIES970_14900	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
NIES970_14930	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NIES970_14960	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
NIES970_15000	ENOG410667J	hydrolase
NIES970_15010	ENOG4105CXN	decarboxylase
NIES970_15020	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
NIES970_15030	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
NIES970_15130	ENOG4105C8Q	Methyl-accepting chemotaxis
NIES970_15150	ENOG4108UNF	response regulator
NIES970_15160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_15190	ENOG4108QDE	fad dependent oxidoreductase
NIES970_15220	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
NIES970_15230	ENOG4105BZU	Histidine kinase
NIES970_15260	ENOG4105BZU	Histidine kinase
NIES970_15320	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
NIES970_15370	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
NIES970_15380	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
NIES970_15450	ENOG4105C9X	ppx gppa phosphatase
NIES970_15500	ENOG4105C12	Phosphoribosylglycinamide synthetase
NIES970_15560	ENOG4105E0A	ABC, transporter
NIES970_15580	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
NIES970_15600	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
NIES970_15610	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
NIES970_15640	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
NIES970_15650	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
NIES970_15660	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
NIES970_15680	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
NIES970_15720	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
NIES970_15730	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
NIES970_15760	ENOG4105EKE	dihydroorotase
NIES970_15770	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
NIES970_15780	ENOG4105C32	Amino acid ABC transporter (Permease)
NIES970_15790	ENOG4105EB3	Histidine kinase
NIES970_15850	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
NIES970_15860	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
NIES970_15900	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
NIES970_15950	ENOG41069TS	Photosystem II reaction center protein M
NIES970_15970	ENOG4107U45	Cobalt transport protein
NIES970_15980	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
NIES970_15990	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
NIES970_16050	ENOG4108S1Y	allophycocyanin alpha-B chain
NIES970_16140	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
NIES970_16210	ENOG4108SDR	phycocyanin, alpha subunit
NIES970_16220	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
NIES970_16250	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_16260	ENOG4105I5W	Transporter
NIES970_16280	ENOG4105D7T	ABC transporter
NIES970_16290	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
NIES970_16310	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
NIES970_16320	ENOG4108UXN	response regulator
NIES970_16340	ENOG4108R0D	protein with myosin-like
NIES970_16350	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
NIES970_16360	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
NIES970_16370	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
NIES970_16390	ENOG4105DCF	alanine dehydrogenase
NIES970_16430	ENOG4108Y85	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
NIES970_16440	ENOG4105CKK	Glycosyl transferase, family 2
NIES970_16450	ENOG410841Q	phosphoesterase PA-phosphatase related protein
NIES970_16600	ENOG4105BZU	Histidine kinase
NIES970_16610	ENOG4105CD2	stage iii sporulation protein aa
NIES970_16670	ENOG4105CD5	CoA-binding domain protein
NIES970_16690	ENOG4105JFG	SpoIID LytB domain protein
NIES970_16700	ENOG4105CBS	Chea signal transduction histidine kinase
NIES970_16710	ENOG4105CDY	transcriptional regulatory protein
NIES970_16720	ENOG4105GR3	Histidine kinase
NIES970_16730	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
NIES970_16750	ENOG4105DR5	peptidase
NIES970_16780	ENOG4105CJ1	ABC, transporter
NIES970_16790	ENOG4105K6T	rare lipoprotein A
NIES970_16800	ENOG4105C4R	Atp-dependent dna helicase
NIES970_16810	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
NIES970_16820	ENOG4105GR3	Histidine kinase
NIES970_16830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_16840	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
NIES970_16860	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
NIES970_16910	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
NIES970_17070	ENOG4107URF	beta-phospho-glucomutase
NIES970_17110	ENOG41083MR	nifu domain-containing protein
NIES970_17120	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
NIES970_17150	ENOG4105DF7	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
NIES970_17160	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
NIES970_17170	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
NIES970_17190	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIES970_17300	ENOG4105C0Z	ABC transporter
NIES970_17310	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
NIES970_17460	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
NIES970_17500	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
NIES970_17560	ENOG4106WTF	Glycosyl transferase, family 2
NIES970_17570	ENOG4105JNK	Glycosyl transferase (Group 1
NIES970_17580	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
NIES970_17590	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
NIES970_17660	ENOG4105BZ1	(ABC) transporter
NIES970_17690	ENOG4105DAY	polysaccharide export protein
NIES970_17700	ENOG4107YJ4	chain length determinant protein
NIES970_17710	ENOG4105PW4	Sugar fermentation stimulation protein homolog
NIES970_17770	ENOG4107QVI	Methyltransferase, type 11
NIES970_17780	ENOG4105E5M	Multidrug resistance protein D
NIES970_17810	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
NIES970_17830	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
NIES970_17850	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
NIES970_17870	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
NIES970_17890	ENOG4105CHH	sulfate transporter
NIES970_17900	ENOG4105D65	subunit l
NIES970_17910	ENOG4105C8S	subunit m
NIES970_17930	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
NIES970_18000	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
NIES970_18010	ENOG4108IAJ	Nad-dependent epimerase dehydratase
NIES970_18040	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
NIES970_18050	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
NIES970_18070	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
NIES970_18090	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
NIES970_18110	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
NIES970_18120	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
NIES970_18130	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
NIES970_18140	ENOG4108SHJ	s-layer protein
NIES970_18190	ENOG4108ZIT	Ferredoxin, 2FE-2S
NIES970_18240	ENOG4105BZU	Histidine kinase
NIES970_18250	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
NIES970_18280	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
NIES970_18300	ENOG4105DSF	transport protein
NIES970_18400	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
NIES970_18420	ENOG4105BZU	Histidine kinase
NIES970_18460	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
NIES970_18470	ENOG4108XAD	Protein of unknown function (DUF1997)
NIES970_18570	ENOG4108VPT	UPF0234 protein
NIES970_18610	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NIES970_18630	ENOG4107RCI	amp-dependent synthetase and ligase
NIES970_18650	ENOG4108S55	polysaccharide biosynthesis protein
NIES970_18670	ENOG4105C8S	subunit m
NIES970_18690	ENOG4105EMN	RNA polymerase sigma factor
NIES970_18710	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
NIES970_18740	ENOG4105K70	DNA-binding protein
NIES970_18750	ENOG4105C02	permease
NIES970_18760	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
NIES970_18770	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
NIES970_18780	ENOG4105CE9	30S ribosomal protein S2
NIES970_18790	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
NIES970_18810	ENOG4105WH1	Two component transcriptional regulator luxr family
NIES970_18840	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
NIES970_18850	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
NIES970_18900	ENOG4108UV1	cellular component movement
NIES970_18970	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
NIES970_18980	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
NIES970_18990	ENOG4105EPJ	extracellular solute-binding protein family 1
NIES970_19010	ENOG4108IJ0	Aspartate ammonia-lyase
NIES970_19030	ENOG4105CT1	(ABC) transporter
NIES970_19040	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
NIES970_19050	ENOG41084A0	50s ribosomal protein L35
NIES970_19080	ENOG4105D8X	mechanosensitive ion channel
NIES970_19090	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
NIES970_19130	ENOG4105CMR	udp-glucose 4-epimerase
NIES970_19140	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
NIES970_19160	ENOG41068G9	50S ribosomal protein L32
NIES970_19180	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
NIES970_19210	ENOG4105N82	Endonuclease
NIES970_19230	ENOG4105C9U	ATP-dependent DNA helicase RecQ
NIES970_19260	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
NIES970_19280	ENOG4105CXI	aluminum resistance protein
NIES970_19290	ENOG4105CNI	cell division protein FtsW
NIES970_19300	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
NIES970_19340	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
NIES970_19350	ENOG4105BZ1	(ABC) transporter
NIES970_19360	ENOG4105CHM	Aminotransferase
NIES970_19380	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
NIES970_19470	ENOG4105ES5	Histidine kinase
NIES970_19480	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
NIES970_19490	ENOG4105C59	p-type ATPase
NIES970_19500	ENOG4107STQ	Multicopper oxidase
NIES970_19520	ENOG41067UF	
NIES970_19540	ENOG4105BZA	Phosphoglycerate kinase
NIES970_19580	ENOG4105CPF	Cell wall formation (By similarity)
NIES970_19590	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
NIES970_19640	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
NIES970_19660	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
NIES970_19750	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
NIES970_19760	ENOG4108JUA	Transcriptional regulator
NIES970_19770	ENOG4108FN7	Aldo keto reductase
NIES970_19790	ENOG4105PNM	synthesis protein
NIES970_19850	ENOG4108HMN	Caspase domain
NIES970_19910	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
NIES970_19920	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NIES970_19930	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NIES970_19940	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NIES970_19970	ENOG4107WDG	serine threonine protein kinase
NIES970_19990	ENOG4108TCG	allophycocyanin beta subunit
NIES970_20010	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
NIES970_20020	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
NIES970_20040	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
NIES970_20120	ENOG4108W6I	photosystem I reaction center protein subunit XI
NIES970_20140	ENOG410902C	phosphohistidine phosphatase, SixA
NIES970_20210	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
NIES970_20230	ENOG4107S2Z	UPF0761 membrane protein
NIES970_20270	ENOG4105C8M	UPF0272 protein
NIES970_20280	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
NIES970_20300	ENOG4105CB5	ATP-dependent DNA helicase recG
NIES970_20310	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
NIES970_20330	ENOG4105C6E	dna polymerase iii
NIES970_20340	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
NIES970_20350	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NIES970_20360	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NIES970_20390	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
NIES970_20400	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
NIES970_20440	ENOG4105QUE	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
NIES970_20490	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
NIES970_20510	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
NIES970_20520	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NIES970_20530	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
NIES970_20540	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
NIES970_20550	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
NIES970_20580	ENOG4108Z6B	deaminase
NIES970_20600	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
NIES970_20620	ENOG4105C4R	Atp-dependent dna helicase
NIES970_20740	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NIES970_20750	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
NIES970_20760	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
NIES970_20790	ENOG4105F8J	Adenylate Guanylate cyclase
NIES970_20800	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
NIES970_20820	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
NIES970_20860	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NIES970_20870	ENOG4107TS3	membrane protein, TerC
NIES970_20890	ENOG4108N5B	2-phosphosulfolactate phosphatase
NIES970_20900	ENOG4105G5W	regulator Fur family
NIES970_20910	ENOG4105M08	Membrane
NIES970_20930	ENOG4105DEF	Extracellular solute-binding protein, family 5
NIES970_20960	ENOG4107QW3	Sucrose phosphorylase
NIES970_20970	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
NIES970_20990	ENOG4105BZU	Histidine kinase
NIES970_21030	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
NIES970_21040	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
NIES970_21090	ENOG4105IJJ	transcriptional regulator, crp fnr family
NIES970_21100	ENOG4105CSR	polyphosphate kinase 2
NIES970_21120	ENOG4105CVJ	phosphoglycerate mutase
NIES970_21150	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
NIES970_21190	ENOG4108IJ9	(ABC) transporter
NIES970_21240	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
NIES970_21250	ENOG4108R6K	riboflavin synthase, subunit alpha
NIES970_21280	ENOG4107ZYR	domain protein
NIES970_21300	ENOG4108TJN	glycosyl transferase group 1
NIES970_21310	ENOG4108JQ6	ABC transporter
NIES970_21320	ENOG4105BZU	Histidine kinase
NIES970_21360	ENOG4105CUT	histidyl-tRNA synthetase
NIES970_21380	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
NIES970_21400	ENOG4107YUH	hydrolase
NIES970_21410	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
NIES970_21430	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
NIES970_21440	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
NIES970_21450	ENOG4105E2Z	phosphate ABC transporter (Permease
NIES970_21470	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
NIES970_21500	ENOG4105K8N	protein family UPF0079, ATPase
NIES970_21530	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
NIES970_21560	ENOG4105KAF	membrAne
NIES970_21600	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
NIES970_21620	ENOG4105CJN	penicillin-binding protein
NIES970_21660	ENOG4105EMN	RNA polymerase sigma factor
NIES970_21690	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
NIES970_21740	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
NIES970_21750	ENOG4108ZAF	Molybdopterin
NIES970_21760	ENOG4105DC1	bifunctional purine biosynthesis protein purh
NIES970_21820	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
NIES970_21870	ENOG4105BZU	Histidine kinase
NIES970_21900	ENOG4107QZ7	Cellulose synthase catalytic subunit
NIES970_21910	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
NIES970_21950	ENOG4105C59	p-type ATPase
NIES970_22020	ENOG4105C8S	subunit m
NIES970_22040	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
NIES970_22080	ENOG4105EEK	Polypeptide
NIES970_22090	ENOG4107SWE	Methyltransferase
NIES970_22150	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
NIES970_22180	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
NIES970_22200	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
NIES970_22210	ENOG4105CRE	cytochrome C
NIES970_22230	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
NIES970_22270	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
NIES970_22280	ENOG4105FBM	allophycocyanin beta subunit
NIES970_22290	ENOG4108MAQ	allophycocyanin alpha
NIES970_22350	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_22400	ENOG4105C72	UPF0176 protein
NIES970_22410	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
NIES970_22420	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
NIES970_22430	ENOG4105W87	Cbs domain
NIES970_22440	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIES970_22460	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
NIES970_22540	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
NIES970_22570	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
NIES970_22710	ENOG4108PJD	permease
NIES970_22720	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NIES970_22740	ENOG4105D0S	secretion protein (HlyD
NIES970_22750	ENOG4105CJ1	ABC, transporter
NIES970_22770	ENOG4107QWP	ABC-2 type transporter
NIES970_22780	ENOG4108KXV	response regulator
NIES970_22810	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
NIES970_22820	ENOG4108KGH	TRANSCRIPTIONal
NIES970_22890	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
NIES970_22970	ENOG4105KC4	UPF0296 protein
NIES970_23000	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
NIES970_23150	ENOG4105CNN	ABC, transporter
NIES970_23160	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
NIES970_23170	ENOG4107YCR	Transcriptional regulator, ARSR family
NIES970_23180	ENOG4106DI1	Metallothionein family 14
NIES970_23200	ENOG4105JZI	cytochrome P450
NIES970_23220	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
NIES970_23240	ENOG4105C8T	Leucyl-tRNA synthetase
NIES970_23270	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
NIES970_23280	ENOG4108N0M	stress protein
NIES970_23290	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
NIES970_23350	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
NIES970_23360	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
NIES970_23400	ENOG41083Z3	extracellular ligand-binding receptor
NIES970_23420	ENOG4108I0Q	anthranilate phosphoribosyltransferase
NIES970_23450	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
NIES970_23480	ENOG4105D6V	phycocyanin beta subunit
NIES970_23490	ENOG4108SDR	phycocyanin, alpha subunit
NIES970_23500	ENOG4108MZQ	phycobilisome linker polypeptide
NIES970_23510	ENOG41065ZC	Rod linker protein, associated with phycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer
NIES970_23520	ENOG41078GB	pbs lyase
NIES970_23530	ENOG4108V9J	phycocyanobilin lyase
NIES970_23570	ENOG4107YU2	histidine triad (hIT) protein
NIES970_23620	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
NIES970_23630	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
NIES970_23640	ENOG4105CJ1	ABC, transporter
NIES970_23670	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
NIES970_23710	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
NIES970_23720	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
NIES970_23730	ENOG4105XCI	PucC protein
NIES970_23740	ENOG41083KH	UPF0102 protein
NIES970_23760	ENOG4105C9B	Cysteine desulfurase
NIES970_23790	ENOG410848D	S4 domain protein YaaA
NIES970_23810	ENOG4108K5P	(LipO)protein
NIES970_23830	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
NIES970_23880	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
NIES970_23920	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
NIES970_23960	ENOG4106855	Competence protein
NIES970_23970	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
NIES970_23980	ENOG4105C8S	subunit m
NIES970_24090	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
NIES970_24140	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
NIES970_24200	ENOG4108MUZ	hydrolase
NIES970_24210	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
NIES970_24250	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
NIES970_24320	ENOG4105BZU	Histidine kinase
NIES970_24340	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
NIES970_24360	ENOG4105CEP	NADH dehydrogenase
NIES970_24390	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
NIES970_24400	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
NIES970_24410	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
NIES970_24450	ENOG4105DQ4	alcohol dehydrogenase
NIES970_24470	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
NIES970_24500	ENOG4105CHF	Glutathione S-transferase
NIES970_24550	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
NIES970_24570	ENOG4105D9M	gamma-glutamylcysteine synthetase
NIES970_24590	ENOG4105CQC	Prephenate dehydratase
NIES970_24640	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
NIES970_24660	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
NIES970_24690	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
NIES970_24760	ENOG4105TQG	cytochrome C, class I
NIES970_24770	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
NIES970_24920	ENOG4108JPZ	Monovalent cation H antiporter subunit D
NIES970_24950	ENOG4105CHH	sulfate transporter
NIES970_24960	ENOG4105CA3	membrane-bound lytic murein transglycosylase
NIES970_24970	ENOG4107PU6	Membrane
NIES970_25000	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
NIES970_25020	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
NIES970_25100	ENOG4105CKI	cobalamin synthesis protein
NIES970_25110	ENOG4105BZU	Histidine kinase
NIES970_25160	ENOG4105CP9	extracellular ligand-binding receptor
NIES970_25170	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
NIES970_25180	ENOG4105BZU	Histidine kinase
NIES970_25190	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_25210	ENOG4105K5B	UPF0225 protein
NIES970_25220	ENOG4105CEN	a g-specific adenine glycosylase
NIES970_25250	ENOG4105D64	Mechanosensitive ion channel
NIES970_25270	ENOG4105C5F	glutamine synthetase
NIES970_25280	ENOG4105VFU	Rna-binding protein
NIES970_25290	ENOG4105DGU	Histone deacetylase
NIES970_25300	ENOG4108IV0	ABC, transporter
NIES970_25350	ENOG4105DFE	Dna adenine methylase
NIES970_25370	ENOG4108I0Q	anthranilate phosphoribosyltransferase
NIES970_25390	ENOG4105C7B	Threonine dehydratase
NIES970_25410	ENOG4105K63	Thioredoxin
NIES970_25480	ENOG4108VCT	Sulfite exporter TauE/SafE
NIES970_25500	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
NIES970_25510	ENOG4105CHW	UPF0052 protein
NIES970_25550	ENOG4105CQB	FAD linked oxidase domain protein
NIES970_25560	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
NIES970_25580	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
NIES970_25590	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
NIES970_25600	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
NIES970_25620	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
NIES970_25660	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
NIES970_25690	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NIES970_25770	ENOG4105D3G	Pseudouridine synthase
NIES970_25840	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
NIES970_25860	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
NIES970_25880	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
NIES970_25930	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
NIES970_25940	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
NIES970_25960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_25980	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
NIES970_25990	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
NIES970_26010	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
NIES970_26030	ENOG4105CEV	competence damage-inducible protein
NIES970_26050	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_26060	ENOG4105NZG	Ferredoxin
NIES970_26110	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
NIES970_26120	ENOG4105CAS	nag kinase
NIES970_26170	ENOG4105BZU	Histidine kinase
NIES970_26190	ENOG41083UI	stage II sporulation protein
NIES970_26210	ENOG41083UI	stage II sporulation protein
NIES970_26280	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
NIES970_26290	ENOG4105CJN	penicillin-binding protein
NIES970_26300	ENOG4105BZU	Histidine kinase
NIES970_26320	ENOG4105CP2	von willebrand factor, type a
NIES970_26330	ENOG4105C8N	cysteinyl-tRNA synthetase
NIES970_26350	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
NIES970_26360	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
NIES970_26390	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
NIES970_26400	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
NIES970_26410	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
NIES970_26430	ENOG4105EIE	fructose-bisphosphate aldolase
NIES970_26440	ENOG4105EIE	fructose-bisphosphate aldolase
NIES970_26510	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
NIES970_26520	ENOG4106H78	methyltransferase
NIES970_26550	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
NIES970_26560	ENOG4105DWF	phosphomethylpyrimidine kinase
NIES970_26570	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
NIES970_26580	ENOG4105DBI	uridine monophosphokinase
NIES970_26620	ENOG4105CBS	Chea signal transduction histidine kinase
NIES970_26650	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
NIES970_26660	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_26690	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
NIES970_26820	ENOG4105M3Z	response regulator
NIES970_26850	ENOG4105CBS	Chea signal transduction histidine kinase
NIES970_26880	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
NIES970_26890	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
NIES970_26900	ENOG41081UC	Inherit from COG: Competence protein
NIES970_26940	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
NIES970_26960	ENOG4105M6F	mutator MutT protein
NIES970_26970	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
NIES970_26990	ENOG4105DJZ	UPF0182 protein
NIES970_27000	ENOG4105CGH	5'-nucleotidase
NIES970_27020	ENOG4105CNG	UPF0061 protein
NIES970_27030	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
NIES970_27040	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NIES970_27050	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NIES970_27060	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
NIES970_27070	ENOG4105CDH	Citrulline--aspartate ligase
NIES970_27130	ENOG4105C7K	acetolactate synthase
NIES970_27180	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
NIES970_27280	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
NIES970_27290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
NIES970_27300	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NIES970_27310	ENOG4105C5E	polysaccharide biosynthesis protein
NIES970_27320	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
NIES970_27330	ENOG4107TY6	Acylneuraminate cytidylyltransferase
NIES970_27380	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
NIES970_27390	ENOG4105FJR	Lmbe family
NIES970_27400	ENOG4105D2T	synthase
NIES970_27410	ENOG4105BZ1	(ABC) transporter
NIES970_27440	ENOG4105BZ1	(ABC) transporter
NIES970_27470	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
NIES970_27490	ENOG4105E0A	ABC, transporter
NIES970_27500	ENOG4108IHU	transport system permease protein
NIES970_27510	ENOG4105DQ5	transport system permease protein
NIES970_27560	ENOG4108MES	Periplasmic binding protein
NIES970_27570	ENOG4105E0K	tonB-dependent siderophore receptor
NIES970_27590	ENOG4105BZ1	(ABC) transporter
NIES970_27630	ENOG4108MES	Periplasmic binding protein
NIES970_27860	ENOG4105C5I	Dehydrogenase
NIES970_27960	ENOG4105D7T	ABC transporter
NIES970_28000	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
NIES970_28120	ENOG4105DY8	decarboxylase
NIES970_28140	ENOG4105D52	delta-aminolevulinic acid dehydratase
NIES970_28150	ENOG4105EUJ	GTP cyclohydrolase i
NIES970_28200	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
NIES970_28240	ENOG4105KCK	Peptidoglycan-associated lipoprotein
NIES970_28340	ENOG4105BZU	Histidine kinase
NIES970_28350	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NIES970_28370	ENOG4105CJ1	ABC, transporter
NIES970_28380	ENOG4105E3A	(ABC) transporter
NIES970_28390	ENOG4105EG6	Saccharopine dehydrogenase
NIES970_28530	ENOG4105CNF	WD-40 repeat protein
NIES970_28540	ENOG4105D1H	recombination factor protein RarA
NIES970_28600	ENOG4105EMU	Dehydrogenase
NIES970_28790	ENOG4105H3G	oxidoreductase
NIES970_28800	ENOG4105WH1	Two component transcriptional regulator luxr family
NIES970_28830	ENOG4105BZU	Histidine kinase
NIES970_28920	ENOG4105E3B	Multicopper oxidase
NIES970_29000	ENOG4105BZU	Histidine kinase
NIES970_29010	ENOG4105WH1	Two component transcriptional regulator luxr family
NIES970_29080	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
NIES970_29260	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
NIES970_29460	ENOG4105C3J	Cysteine desulfurase
NIES970_29510	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
NIES970_29560	ENOG4107QJE	Chromosome Partitioning Protein
NIES970_29570	ENOG4105FA0	parb-like partition protein
NIES970_29600	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
NIES970_29650	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NIES970_29680	ENOG4105D29	Helix-turn-helix type 11 domain protein
NIES970_29710	ENOG4105DTT	CRISPR-associated helicase, cas3
NIES970_29720	ENOG4108WIP	
NIES970_29730	ENOG4108R5Z	fruiting body developmental protein
NIES970_29790	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
NIES970_29800	ENOG4105WBS	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
NIES970_29920	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
NIES970_29980	ENOG4105CFI	type iii restriction protein res subunit
NIES970_30060	ENOG4108C33	Resolvase
NIES970_30070	ENOG4107QJE	Chromosome Partitioning Protein
NIES970_30090	ENOG4105CVR	type I restriction-modification system