locus-tag	class	description
AWQ22_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWQ22_00030	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AWQ22_00035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWQ22_00040	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AWQ22_00040	COG0662	Cupin 2, conserved barrel domain protein
AWQ22_00050	COG1830	Aldolase
AWQ22_00055	COG4636	protein conserved in cyanobacteria
AWQ22_00090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_00095	COG0742	ribosomal rna small subunit methyltransferase
AWQ22_00115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWQ22_00120	COG0351	phosphomethylpyrimidine kinase
AWQ22_00125	COG1160	GTP binding
AWQ22_00140	COG0572	uridine kinase
AWQ22_00145	COG1280	lysine exporter protein (LysE YggA)
AWQ22_00155	COG0783	Belongs to the Dps family
AWQ22_00165	COG1253	flavin adenine dinucleotide binding
AWQ22_00175	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWQ22_00185	COG0180	Tryptophanyl-tRNA synthetase
AWQ22_00195	COG0384	phenazine biosynthesis protein PhzF
AWQ22_00200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_00230	COG0784	Response regulator, receiver
AWQ22_00245	COG0840	transmembrane signaling receptor activity
AWQ22_00245	COG2203	Gaf domain
AWQ22_00265	COG0511	ligase activity, forming carbon-carbon bonds
AWQ22_00270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWQ22_00280	COG1487	ribonuclease activity
AWQ22_00300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWQ22_00310	COG0494	nUDIX hydrolase
AWQ22_00315	COG0571	ribonuclease III activity
AWQ22_00330	COG0737	Belongs to the 5'-nucleotidase family
AWQ22_00375	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ22_00390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWQ22_00425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWQ22_00430	COG0148	phosphopyruvate hydratase activity
AWQ22_00435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWQ22_00440	COG1472	Belongs to the glycosyl hydrolase 3 family
AWQ22_00455	COG3937	granule-associated protein
AWQ22_00465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ22_00475	COG3409	Peptidoglycan-binding domain 1 protein
AWQ22_00475	COG3773	Cell wall hydrolase
AWQ22_00480	COG0612	Peptidase, M16
AWQ22_00485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWQ22_00485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWQ22_00520	COG0083	homoserine kinase activity
AWQ22_00540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ22_00545	COG0456	acetyltransferase
AWQ22_00555	COG0019	diaminopimelate decarboxylase activity
AWQ22_00560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWQ22_00565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWQ22_00585	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWQ22_00595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWQ22_00605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWQ22_00610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ22_00615	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ22_00620	COG2010	Cytochrome c
AWQ22_00640	COG0656	L-ascorbic acid biosynthetic process
AWQ22_00645	COG0386	Belongs to the glutathione peroxidase family
AWQ22_00655	COG0629	single-stranded DNA binding
AWQ22_00660	COG4172	Belongs to the ABC transporter superfamily
AWQ22_00665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWQ22_00670	COG0494	nUDIX hydrolase
AWQ22_00675	COG1160	GTP binding
AWQ22_00680	COG3268	Saccharopine dehydrogenase
AWQ22_00685	COG2116	formate transmembrane transporter activity
AWQ22_00690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ22_00700	COG1959	2 iron, 2 sulfur cluster binding
AWQ22_00715	COG0789	Transcriptional regulator
AWQ22_00725	COG1175	transmembrane transport
AWQ22_00730	COG0728	peptidoglycan biosynthetic process
AWQ22_00740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWQ22_00750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AWQ22_00765	COG0542	response to heat
AWQ22_00780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWQ22_00795	COG0459	protein refolding
AWQ22_00800	COG5002	protein histidine kinase activity
AWQ22_00800	COG2205	protein histidine kinase activity
AWQ22_00800	COG0784	Response regulator, receiver
AWQ22_00815	COG0737	Belongs to the 5'-nucleotidase family
AWQ22_00820	COG0668	transmembrane transport
AWQ22_00840	COG0756	dUTP diphosphatase activity
AWQ22_00865	COG3239	Fatty acid desaturase
AWQ22_00880	COG0205	6-phosphofructokinase activity
AWQ22_00895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ22_00900	COG1131	(ABC) transporter
AWQ22_00905	COG2010	Cytochrome c
AWQ22_00920	COG2124	cytochrome p450
AWQ22_00925	COG0583	DNA-binding transcription factor activity
AWQ22_00930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ22_00935	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_00945	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ22_00950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWQ22_00950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWQ22_00955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWQ22_00960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWQ22_00990	COG0457	Tetratricopeptide repeat
AWQ22_00990	COG0463	Glycosyl transferase, family 2
AWQ22_01005	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ22_01030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWQ22_01035	COG4636	protein conserved in cyanobacteria
AWQ22_01040	COG0804	urea catabolic process
AWQ22_01065	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AWQ22_01075	COG3259	Nickel-dependent hydrogenase
AWQ22_01085	COG0375	protein maturation
AWQ22_01090	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ22_01095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AWQ22_01100	COG0298	carbon dioxide binding
AWQ22_01120	COG1490	D-aminoacyl-tRNA deacylase activity
AWQ22_01125	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ22_01135	COG0793	Belongs to the peptidase S41A family
AWQ22_01145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ22_01150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ22_01155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ22_01160	COG0745	RESPONSE REGULATOR receiver
AWQ22_01170	COG2003	Belongs to the UPF0758 family
AWQ22_01175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWQ22_01180	COG0312	modulator of DNA gyrase
AWQ22_01200	COG0316	Belongs to the HesB IscA family
AWQ22_01205	COG0569	domain protein
AWQ22_01210	COG1773	rubredoxin
AWQ22_01215	COG4447	cellulose binding
AWQ22_01245	COG3977	Valine--pyruvate aminotransferase
AWQ22_01260	COG0322	excinuclease ABC activity
AWQ22_01275	COG1131	(ABC) transporter
AWQ22_01285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWQ22_01300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ22_01310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWQ22_01325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWQ22_01325	COG0574	Belongs to the PEP-utilizing enzyme family
AWQ22_01355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWQ22_01375	COG1968	undecaprenyl-diphosphatase activity
AWQ22_01385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWQ22_01395	COG0516	GMP reductase activity
AWQ22_01415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ22_01425	COG1834	amidinotransferase
AWQ22_01430	COG0724	RNA recognition motif
AWQ22_01435	COG2239	Acts as a magnesium transporter
AWQ22_01465	COG0352	thiamine-phosphate diphosphorylase activity
AWQ22_01470	COG0602	queuosine metabolic process
AWQ22_01475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWQ22_01480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ22_01485	COG0589	response to stress
AWQ22_01485	COG0475	glutathione-regulated potassium exporter activity
AWQ22_01495	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWQ22_01505	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AWQ22_01510	COG4251	negative regulation of phosphorylation
AWQ22_01520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ22_01530	COG0436	Aminotransferase
AWQ22_01535	COG3118	belongs to the thioredoxin family
AWQ22_01540	COG1842	Phage shock protein A
AWQ22_01545	COG4251	negative regulation of phosphorylation
AWQ22_01550	COG0133	tryptophan synthase activity
AWQ22_01575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWQ22_01580	COG0783	Belongs to the Dps family
AWQ22_01605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWQ22_01615	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWQ22_01625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWQ22_01640	COG0673	inositol 2-dehydrogenase activity
AWQ22_01650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWQ22_01655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWQ22_01660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWQ22_01670	COG0450	alkyl hydroperoxide reductase
AWQ22_01675	COG1555	photosystem II stabilization
AWQ22_01685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWQ22_01690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWQ22_01695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWQ22_01700	COG1032	radical SAM domain protein
AWQ22_01710	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AWQ22_01715	COG1640	4-alpha-glucanotransferase
AWQ22_01725	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AWQ22_01750	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ22_01755	COG0346	lactoylglutathione lyase activity
AWQ22_01765	COG4953	penicillin-binding protein 1C
AWQ22_01775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ22_01785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWQ22_01785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWQ22_01790	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ22_01795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWQ22_01805	COG0517	IMP dehydrogenase activity
AWQ22_01805	COG0516	GMP reductase activity
AWQ22_01815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_01830	COG0509	glycine decarboxylation via glycine cleavage system
AWQ22_01835	COG0006	proline dipeptidase activity
AWQ22_01840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWQ22_01845	COG0484	heat shock protein binding
AWQ22_01855	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AWQ22_01875	COG0606	chelatase, subunit chli
AWQ22_01905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ22_01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWQ22_01915	COG0157	Belongs to the NadC ModD family
AWQ22_01940	COG2208	phosphoserine phosphatase activity
AWQ22_01945	COG1216	Glycosyl transferase, family 2
AWQ22_01950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWQ22_01960	COG2010	Cytochrome c
AWQ22_01980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ22_01995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ22_02005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWQ22_02010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ22_02020	COG0752	glycyl-tRNA synthetase alpha subunit
AWQ22_02035	COG1214	PFAM Peptidase M22, glycoprotease
AWQ22_02040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWQ22_02055	COG1606	tRNA processing
AWQ22_02090	COG0285	dihydrofolate synthase activity
AWQ22_02130	COG2244	polysaccharide biosynthetic process
AWQ22_02135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWQ22_02140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ22_02155	COG2089	acid synthase
AWQ22_02160	COG1083	cytidylyl-transferase
AWQ22_02175	COG0673	inositol 2-dehydrogenase activity
AWQ22_02190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWQ22_02205	COG0457	Tetratricopeptide repeat
AWQ22_02210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWQ22_02215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ22_02215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ22_02220	COG3850	Histidine kinase
AWQ22_02220	COG4999	Histidine kinase
AWQ22_02220	COG3437	response regulator, receiver
AWQ22_02220	COG2205	protein histidine kinase activity
AWQ22_02230	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWQ22_02235	COG0542	response to heat
AWQ22_02240	COG1192	Involved in chromosome partitioning
AWQ22_02250	COG0339	signal peptide processing
AWQ22_02255	COG0308	aminopeptidase N
AWQ22_02260	COG0673	inositol 2-dehydrogenase activity
AWQ22_02290	COG0360	Binds together with S18 to 16S ribosomal RNA
AWQ22_02295	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWQ22_02300	COG0747	negative chemotaxis
AWQ22_02305	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ22_02305	COG0515	serine threonine protein kinase
AWQ22_02310	COG0072	phenylalanine-tRNA ligase activity
AWQ22_02310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ22_02320	COG4636	protein conserved in cyanobacteria
AWQ22_02325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ22_02330	COG0497	DNA recombination
AWQ22_02335	COG0676	glucose-6-phosphate 1-epimerase activity
AWQ22_02340	COG0631	protein serine/threonine phosphatase activity
AWQ22_02345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ22_02350	COG3937	granule-associated protein
AWQ22_02355	COG0066	3-isopropylmalate dehydratase activity
AWQ22_02360	COG0720	synthase
AWQ22_02365	COG1070	Carbohydrate kinase
AWQ22_02370	COG0515	serine threonine protein kinase
AWQ22_02375	COG2211	Major facilitator Superfamily
AWQ22_02380	COG3659	wide pore channel activity
AWQ22_02405	COG3781	membrane
AWQ22_02410	COG0668	transmembrane transport
AWQ22_02425	COG2308	Evidence 4 Homologs of previously reported genes of
AWQ22_02445	COG0347	Belongs to the P(II) protein family
AWQ22_02455	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWQ22_02460	COG0443	Heat shock 70 kDa protein
AWQ22_02465	COG0612	Peptidase, M16
AWQ22_02485	COG0058	SHG alpha-glucan phosphorylase activity
AWQ22_02495	COG1994	Peptidase M50
AWQ22_02495	COG0517	IMP dehydrogenase activity
AWQ22_02505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWQ22_02510	COG0745	RESPONSE REGULATOR receiver
AWQ22_02520	COG0140	phosphoribosyl-ATP diphosphatase activity
AWQ22_02520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWQ22_02525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWQ22_02530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWQ22_02540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ22_02545	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWQ22_02550	COG2314	TM2 domain
AWQ22_02560	COG0745	RESPONSE REGULATOR receiver
AWQ22_02565	COG1126	abc transporter atp-binding protein
AWQ22_02605	COG1943	Transposase
AWQ22_02625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ22_02625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWQ22_02645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWQ22_02650	COG0436	Aminotransferase
AWQ22_02655	COG0850	regulation of cytokinetic process
AWQ22_02660	COG2894	cell division
AWQ22_02665	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AWQ22_02675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWQ22_02695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWQ22_02700	COG0671	phosphoesterase, PA-phosphatase related
AWQ22_02705	COG0612	Peptidase, M16
AWQ22_02710	COG2226	methyltransferase
AWQ22_02720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWQ22_02725	COG0416	fatty acid biosynthetic process
AWQ22_02745	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ22_02760	COG4636	protein conserved in cyanobacteria
AWQ22_02765	COG1215	transferase activity, transferring glycosyl groups
AWQ22_02790	COG0484	heat shock protein binding
AWQ22_02815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWQ22_02820	COG0271	Belongs to the BolA IbaG family
AWQ22_02830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ22_02835	COG0613	PHP domain protein
AWQ22_02840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWQ22_02850	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWQ22_02855	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWQ22_02860	COG0235	Class ii aldolase
AWQ22_02880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWQ22_02885	COG0450	alkyl hydroperoxide reductase
AWQ22_02905	COG0159	tryptophan synthase activity
AWQ22_02915	COG4243	Vitamin k epoxide reductase
AWQ22_02920	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWQ22_02960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWQ22_02965	COG0557	exoribonuclease II activity
AWQ22_02980	COG0475	glutathione-regulated potassium exporter activity
AWQ22_02985	COG2247	cell wall binding repeat
AWQ22_02985	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWQ22_02990	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWQ22_02995	COG0142	geranyltranstransferase activity
AWQ22_03010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ22_03015	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWQ22_03035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ22_03040	COG0798	PFAM Bile acid sodium symporter
AWQ22_03045	COG0640	Transcriptional regulator
AWQ22_03055	COG0750	zinc metalloprotease
AWQ22_03065	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWQ22_03070	COG0149	triose-phosphate isomerase activity
AWQ22_03075	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ22_03075	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ22_03090	COG0018	arginyl-trna synthetase
AWQ22_03100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWQ22_03110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWQ22_03120	COG0371	Dehydrogenase
AWQ22_03125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWQ22_03145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ22_03145	COG0284	orotidine-5'-phosphate decarboxylase activity
AWQ22_03150	COG1136	(ABC) transporter
AWQ22_03150	COG0577	efflux transmembrane transporter activity
AWQ22_03160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWQ22_03170	COG2197	response regulator
AWQ22_03180	COG0251	oxidation-reduction process
AWQ22_03185	COG0513	Belongs to the DEAD box helicase family
AWQ22_03190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ22_03195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWQ22_03200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWQ22_03210	COG0483	inositol monophosphate 1-phosphatase activity
AWQ22_03215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ22_03225	COG0488	(ABC) transporter
AWQ22_03235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWQ22_03240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AWQ22_03250	COG4139	cobalamin transport
AWQ22_03265	COG4771	TonB-dependent receptor
AWQ22_03275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ22_03315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWQ22_03315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWQ22_03320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWQ22_03350	COG0022	dehydrogenase e1 component
AWQ22_03350	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ22_03355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ22_03360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ22_03385	COG2072	flavoprotein involved in K transport
AWQ22_03410	COG2144	transferase activity, transferring acyl groups
AWQ22_03440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ22_03450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWQ22_03455	COG1022	Amp-dependent synthetase and ligase
AWQ22_03465	COG0287	Prephenate dehydrogenase
AWQ22_03470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWQ22_03480	COG3217	Mosc domain protein beta barrel domain protein
AWQ22_03480	COG0633	Ferredoxin
AWQ22_03485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ22_03500	COG0189	ligase activity
AWQ22_03505	COG0189	ligase activity
AWQ22_03505	COG4067	protein conserved in archaea
AWQ22_03535	COG1162	GTPase activity
AWQ22_03545	COG0484	heat shock protein binding
AWQ22_03550	COG0443	Heat shock 70 kDa protein
AWQ22_03590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ22_03595	COG0596	Alpha beta hydrolase
AWQ22_03595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ22_03610	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ22_03635	COG0277	FAD linked oxidase domain protein
AWQ22_03640	COG1132	(ABC) transporter
AWQ22_03645	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWQ22_03650	COG3064	Membrane
AWQ22_03650	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWQ22_03650	COG1073	alpha beta
AWQ22_03655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWQ22_03660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ22_03670	COG0438	transferase activity, transferring glycosyl groups
AWQ22_03680	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWQ22_03700	COG1845	cytochrome c oxidase, subunit III
AWQ22_03710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ22_03725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ22_03740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ22_03750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ22_03755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ22_03765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ22_03770	COG0356	it plays a direct role in the translocation of protons across the membrane
AWQ22_03800	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWQ22_03805	COG0857	belongs to the CobB CobQ family
AWQ22_03815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ22_03825	COG0357	Ribosomal RNA small subunit methyltransferase G
AWQ22_03835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWQ22_03845	COG0779	Required for maturation of 30S ribosomal subunits
AWQ22_03850	COG0195	Participates in both transcription termination and antitermination
AWQ22_03860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWQ22_03865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWQ22_03880	COG3639	organic phosphonate transmembrane transporter activity
AWQ22_03890	COG0515	serine threonine protein kinase
AWQ22_03905	COG0429	hydrolase of the alpha beta-hydrolase fold
AWQ22_03910	COG0488	(ABC) transporter
AWQ22_03920	COG0463	Glycosyl transferase, family 2
AWQ22_03925	COG0681	Belongs to the peptidase S26 family
AWQ22_03945	COG0303	'Molybdopterin
AWQ22_03955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWQ22_03995	COG3659	wide pore channel activity
AWQ22_04010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ22_04020	COG1104	cysteine desulfurase activity
AWQ22_04025	COG1530	ribonuclease E activity
AWQ22_04030	COG3956	TIGRFAM MazG family protein
AWQ22_04045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ22_04050	COG0678	peroxiredoxin activity
AWQ22_04060	COG3273	potassium ion transport
AWQ22_04060	COG0471	metal ion transport
AWQ22_04065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWQ22_04070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWQ22_04075	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AWQ22_04080	COG4208	sulfate ABC transporter
AWQ22_04085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWQ22_04125	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ22_04125	COG0515	serine threonine protein kinase
AWQ22_04145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ22_04160	COG0105	UTP biosynthetic process
AWQ22_04175	COG2226	methyltransferase
AWQ22_04180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWQ22_04195	COG1132	(ABC) transporter
AWQ22_04205	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWQ22_04210	COG1446	asparaginase
AWQ22_04220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ22_04250	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWQ22_04260	COG0456	acetyltransferase
AWQ22_04265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ22_04265	COG2198	Histidine kinase
AWQ22_04265	COG2205	protein histidine kinase activity
AWQ22_04265	COG0784	Response regulator, receiver
AWQ22_04270	COG2048	Heterodisulfide reductase, subunit B
AWQ22_04290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ22_04295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ22_04300	COG0793	Belongs to the peptidase S41A family
AWQ22_04315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWQ22_04350	COG0745	RESPONSE REGULATOR receiver
AWQ22_04355	COG2203	Gaf domain
AWQ22_04360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ22_04365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ22_04380	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AWQ22_04385	COG0745	RESPONSE REGULATOR receiver
AWQ22_04390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ22_04395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ22_04400	COG1116	anion transmembrane transporter activity
AWQ22_04400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ22_04405	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ22_04415	COG2205	protein histidine kinase activity
AWQ22_04425	COG0784	Response regulator, receiver
AWQ22_04425	COG2198	Histidine kinase
AWQ22_04425	COG5002	protein histidine kinase activity
AWQ22_04430	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AWQ22_04435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AWQ22_04440	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ22_04440	COG0515	serine threonine protein kinase
AWQ22_04455	COG0515	serine threonine protein kinase
AWQ22_04455	COG3266	domain, Protein
AWQ22_04465	COG0799	negative regulation of ribosome biogenesis
AWQ22_04470	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ22_04490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWQ22_04495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWQ22_04510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWQ22_04515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWQ22_04520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWQ22_04525	COG0540	Belongs to the ATCase OTCase family
AWQ22_04540	COG3100	YcgL domain-containing protein
AWQ22_04540	COG0561	phosphatase activity
AWQ22_04545	COG0438	transferase activity, transferring glycosyl groups
AWQ22_04550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWQ22_04560	COG0045	succinate-CoA ligase (ADP-forming) activity
AWQ22_04590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWQ22_04605	COG5002	protein histidine kinase activity
AWQ22_04615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_04620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWQ22_04630	COG1691	(AIR) carboxylase
AWQ22_04635	COG0745	RESPONSE REGULATOR receiver
AWQ22_04645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ22_04655	COG1136	(ABC) transporter
AWQ22_04665	COG2166	iron-sulfur cluster assembly
AWQ22_04675	COG0489	protein tyrosine kinase activity
AWQ22_04700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ22_04705	COG4251	negative regulation of phosphorylation
AWQ22_04710	COG1104	cysteine desulfurase activity
AWQ22_04720	COG0713	ATP synthesis coupled electron transport
AWQ22_04725	COG0839	Belongs to the complex I subunit 6 family
AWQ22_04730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_04735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AWQ22_04740	COG1716	ATPase activity
AWQ22_04745	COG0363	glucosamine-6-phosphate deaminase activity
AWQ22_04760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ22_04790	COG0745	RESPONSE REGULATOR receiver
AWQ22_04795	COG1702	phosphate starvation-inducible protein PhoH
AWQ22_04805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ22_04815	COG2310	stress, protein
AWQ22_04825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWQ22_04835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWQ22_04855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ22_04865	COG0233	cytoplasmic translational termination
AWQ22_04870	COG0528	UMP kinase activity
AWQ22_04880	COG0539	negative regulation of cytoplasmic translation
AWQ22_04885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWQ22_04895	COG0564	pseudouridine synthase activity
AWQ22_04930	COG1404	Belongs to the peptidase S8 family
AWQ22_04940	COG0166	Belongs to the GPI family
AWQ22_04965	COG0386	Belongs to the glutathione peroxidase family
AWQ22_04980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ22_04990	COG0434	BtpA family
AWQ22_05005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWQ22_05010	COG0745	RESPONSE REGULATOR receiver
AWQ22_05015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ22_05015	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ22_05030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AWQ22_05035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ22_05040	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ22_05055	COG0594	ribonuclease P activity
AWQ22_05065	COG0706	membrane insertase activity
AWQ22_05080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_05090	COG0784	Response regulator, receiver
AWQ22_05090	COG2205	protein histidine kinase activity
AWQ22_05090	COG5002	protein histidine kinase activity
AWQ22_05115	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ22_05130	COG0025	NhaP-type Na H and K H
AWQ22_05140	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ22_05145	COG0788	formyltetrahydrofolate deformylase activity
AWQ22_05150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWQ22_05190	COG1716	ATPase activity
AWQ22_05215	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ22_05235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWQ22_05240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ22_05245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWQ22_05250	COG0154	amidase activity
AWQ22_05255	COG0222	ribosome binding
AWQ22_05260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWQ22_05265	COG0081	regulation of translation
AWQ22_05270	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWQ22_05275	COG0250	Participates in transcription elongation, termination and antitermination
AWQ22_05280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWQ22_05290	COG0335	large ribosomal subunit rRNA binding
AWQ22_05295	COG3659	wide pore channel activity
AWQ22_05305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWQ22_05310	COG0254	rRNA binding
AWQ22_05315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWQ22_05320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWQ22_05325	COG0101	tRNA pseudouridine synthase activity
AWQ22_05330	COG0203	ribosomal protein L17
AWQ22_05345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWQ22_05355	COG0563	adenylate kinase activity
AWQ22_05360	COG0201	protein transport
AWQ22_05365	COG0200	Binds to the 23S rRNA
AWQ22_05370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWQ22_05375	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWQ22_05380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWQ22_05385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWQ22_05390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWQ22_05395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWQ22_05400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWQ22_05410	COG0255	Belongs to the universal ribosomal protein uL29 family
AWQ22_05415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWQ22_05420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWQ22_05425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWQ22_05430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWQ22_05435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWQ22_05450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWQ22_05455	COG1185	polyribonucleotide nucleotidyltransferase activity
AWQ22_05475	COG0004	ammonium transporteR
AWQ22_05480	COG1012	belongs to the aldehyde dehydrogenase family
AWQ22_05510	COG1012	belongs to the aldehyde dehydrogenase family
AWQ22_05535	COG3688	RNA-binding protein containing a PIN domain
AWQ22_05540	COG2112	serine threonine protein kinase
AWQ22_05550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ22_05560	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWQ22_05575	COG4399	Belongs to the UPF0754 family
AWQ22_05580	COG1333	cytochrome c biogenesis protein
AWQ22_05600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ22_05630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ22_05640	COG2226	methyltransferase
AWQ22_05645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWQ22_05660	COG0643	Histidine kinase
AWQ22_05660	COG2198	Histidine kinase
AWQ22_05665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWQ22_05675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ22_05680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ22_05685	COG0010	Belongs to the arginase family
AWQ22_05695	COG4251	negative regulation of phosphorylation
AWQ22_05705	COG0445	tRNA wobble uridine modification
AWQ22_05710	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWQ22_05735	COG1196	nuclear chromosome segregation
AWQ22_05745	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWQ22_05750	COG2226	methyltransferase
AWQ22_05765	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWQ22_05780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWQ22_05800	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWQ22_05805	COG0616	signal peptide processing
AWQ22_05815	COG0385	Bile acid
AWQ22_05820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWQ22_05840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWQ22_05845	COG0189	ligase activity
AWQ22_05865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWQ22_05905	COG0561	phosphatase activity
AWQ22_05910	COG1982	Orn Lys Arg decarboxylase major
AWQ22_05915	COG0109	protoheme IX farnesyltransferase activity
AWQ22_05920	COG1612	heme a metabolic process
AWQ22_05925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ22_05930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWQ22_05935	COG1845	cytochrome c oxidase, subunit III
AWQ22_05950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWQ22_05965	COG0629	single-stranded DNA binding
AWQ22_05970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ22_05975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ22_05980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWQ22_05995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWQ22_06000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_06005	COG0668	transmembrane transport
AWQ22_06025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ22_06065	COG0270	DNA (cytosine-5-)-methyltransferase activity
AWQ22_06080	COG0826	peptidase U32
AWQ22_06090	COG1587	Uroporphyrinogen-III synthase
AWQ22_06095	COG0740	serine-type endopeptidase activity
AWQ22_06100	COG0740	serine-type endopeptidase activity
AWQ22_06105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWQ22_06110	COG3118	belongs to the thioredoxin family
AWQ22_06120	COG0583	DNA-binding transcription factor activity
AWQ22_06130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWQ22_06140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ22_06145	COG0436	Aminotransferase
AWQ22_06160	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ22_06180	COG1253	flavin adenine dinucleotide binding
AWQ22_06200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWQ22_06210	COG0525	valine-tRNA ligase activity
AWQ22_06220	COG0772	Belongs to the SEDS family
AWQ22_06255	COG0745	RESPONSE REGULATOR receiver
AWQ22_06260	COG0805	protein transport
AWQ22_06280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWQ22_06300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ22_06330	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AWQ22_06385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ22_06390	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWQ22_06395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWQ22_06400	COG2264	protein methyltransferase activity
AWQ22_06415	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ22_06435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWQ22_06440	COG0395	ABC-type sugar transport system, permease component
AWQ22_06445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ22_06460	COG0653	protein targeting
AWQ22_06470	COG2205	protein histidine kinase activity
AWQ22_06470	COG5002	protein histidine kinase activity
AWQ22_06470	COG0784	Response regulator, receiver
AWQ22_06480	COG0592	DNA-directed DNA polymerase activity
AWQ22_06510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWQ22_06515	COG0632	four-way junction helicase activity
AWQ22_06520	COG0305	Participates in initiation and elongation during chromosome replication
AWQ22_06520	COG1372	Participates in initiation and elongation during chromosome replication
AWQ22_06520	COG0305	Participates in initiation and elongation during chromosome replication
AWQ22_06520	COG1372	Participates in initiation and elongation during chromosome replication
AWQ22_06530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWQ22_06535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWQ22_06540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWQ22_06545	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWQ22_06550	COG0024	Methionine aminopeptidase
AWQ22_06555	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWQ22_06565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ22_06565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ22_06570	COG0156	8-amino-7-oxononanoate synthase activity
AWQ22_06585	COG0824	Thioesterase
AWQ22_06590	COG0347	Belongs to the P(II) protein family
AWQ22_06600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWQ22_06605	COG1366	Belongs to the anti-sigma-factor antagonist family
AWQ22_06615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AWQ22_06620	COG0716	FMN binding
AWQ22_06635	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWQ22_06655	COG0672	)-iron permease
AWQ22_06665	COG1494	fructose-1,6-bisphosphatase
AWQ22_06670	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWQ22_06700	COG0745	RESPONSE REGULATOR receiver
AWQ22_06705	COG1372	Participates in initiation and elongation during chromosome replication
AWQ22_06705	COG0719	Fe-S assembly protein
AWQ22_06710	COG0717	Belongs to the dCTP deaminase family
AWQ22_06725	COG2223	nitrite transmembrane transporter activity
AWQ22_06730	COG0243	molybdopterin cofactor binding
AWQ22_06740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWQ22_06745	COG0848	biopolymer transport protein
AWQ22_06750	COG0811	peptide transport
AWQ22_06755	COG0831	urea catabolic process
AWQ22_06770	COG0426	domain, Protein
AWQ22_06770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ22_06790	COG0617	tRNA 3'-terminal CCA addition
AWQ22_06815	COG1566	PFAM secretion protein HlyD family protein
AWQ22_06835	COG1192	Involved in chromosome partitioning
AWQ22_06880	COG0393	Putative heavy-metal-binding
AWQ22_06910	COG1372	Participates in initiation and elongation during chromosome replication
AWQ22_06910	COG0187	DNA topoisomerase II activity
AWQ22_06915	COG2046	Belongs to the sulfate adenylyltransferase family
AWQ22_06920	COG0358	DNA primase activity
AWQ22_06940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ22_06945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ22_06955	COG0191	fructose-bisphosphate aldolase activity
AWQ22_06960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWQ22_06965	COG2205	protein histidine kinase activity
AWQ22_06970	COG5001	Diguanylate cyclase
AWQ22_06975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ22_07000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWQ22_07005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWQ22_07005	COG0519	Catalyzes the synthesis of GMP from XMP
AWQ22_07010	COG5002	protein histidine kinase activity
AWQ22_07045	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWQ22_07050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ22_07055	COG0840	transmembrane signaling receptor activity
AWQ22_07065	COG0745	RESPONSE REGULATOR receiver
AWQ22_07080	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AWQ22_07100	COG1178	ABC-type Fe3 transport system permease component
AWQ22_07105	COG0784	Response regulator, receiver
AWQ22_07105	COG2198	Histidine kinase
AWQ22_07105	COG5002	protein histidine kinase activity
AWQ22_07115	COG5002	protein histidine kinase activity
AWQ22_07140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ22_07145	COG2255	four-way junction helicase activity
AWQ22_07165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ22_07195	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ22_07200	COG0248	Ppx GppA phosphatase
AWQ22_07205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWQ22_07220	COG5002	protein histidine kinase activity
AWQ22_07225	COG0151	Belongs to the GarS family
AWQ22_07230	COG0392	lysyltransferase activity
AWQ22_07235	COG0587	DNA-directed DNA polymerase activity
AWQ22_07240	COG4636	protein conserved in cyanobacteria
AWQ22_07245	COG2133	pyrroloquinoline quinone binding
AWQ22_07250	COG0163	prenyltransferase activity
AWQ22_07260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWQ22_07265	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AWQ22_07300	COG0504	CTP synthase activity
AWQ22_07310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWQ22_07315	COG0463	Glycosyl transferase, family 2
AWQ22_07325	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AWQ22_07335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWQ22_07340	COG3536	Protein conserved in bacteria
AWQ22_07375	COG0681	Belongs to the peptidase S26 family
AWQ22_07385	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ22_07395	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWQ22_07415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AWQ22_07415	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AWQ22_07415	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWQ22_07415	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWQ22_07440	COG0438	transferase activity, transferring glycosyl groups
AWQ22_07440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWQ22_07445	COG1132	(ABC) transporter
AWQ22_07460	COG5002	protein histidine kinase activity
AWQ22_07465	COG0745	RESPONSE REGULATOR receiver
AWQ22_07480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ22_07495	COG3429	Glucose-6-phosphate dehydrogenase subunit
AWQ22_07495	COG3409	Peptidoglycan-binding domain 1 protein
AWQ22_07500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWQ22_07505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ22_07510	COG1566	PFAM secretion protein HlyD family protein
AWQ22_07515	COG0586	Pfam SNARE associated Golgi protein
AWQ22_07530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ22_07530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ22_07540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWQ22_07545	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ22_07560	COG2843	Capsule synthesis protein
AWQ22_07570	COG0667	Aldo Keto reductase
AWQ22_07580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ22_07615	COG1136	(ABC) transporter
AWQ22_07660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ22_07670	COG0529	Catalyzes the synthesis of activated sulfate
AWQ22_07675	COG0617	tRNA 3'-terminal CCA addition
AWQ22_07690	COG0175	sulfate reduction
AWQ22_07695	COG0359	binds to the 23S rRNA
AWQ22_07700	COG2199	diguanylate cyclase activity
AWQ22_07705	COG0489	protein tyrosine kinase activity
AWQ22_07740	COG1132	(ABC) transporter
AWQ22_07745	COG1216	Glycosyl transferase, family 2
AWQ22_07755	COG1442	glycosyl transferase family 8
AWQ22_07765	COG0438	transferase activity, transferring glycosyl groups
AWQ22_07805	COG0297	glycogen (starch) synthase activity
AWQ22_07835	COG2171	N-acyltransferase activity
AWQ22_07840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWQ22_07850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ22_07860	COG1077	Cell shape determining protein MreB Mrl
AWQ22_07895	COG0297	glycogen (starch) synthase activity
AWQ22_07905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWQ22_07910	COG0740	serine-type endopeptidase activity
AWQ22_07950	COG0557	exoribonuclease II activity
AWQ22_07960	COG0047	phosphoribosylformylglycinamidine synthase activity
AWQ22_07965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ22_07970	COG0701	Predicted permease
AWQ22_07975	COG0745	RESPONSE REGULATOR receiver
AWQ22_07980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ22_07980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ22_07985	COG2267	carboxylic ester hydrolase activity
AWQ22_08010	COG0095	Lipoate-protein ligase
AWQ22_08015	COG0515	serine threonine protein kinase
AWQ22_08015	COG3266	domain, Protein
AWQ22_08020	COG2226	methyltransferase
AWQ22_08030	COG2084	Dehydrogenase
AWQ22_08050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWQ22_08055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWQ22_08060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ22_08065	COG0457	Tetratricopeptide repeat
AWQ22_08080	COG4783	chaperone-mediated protein folding
AWQ22_08095	COG1090	epimerase
AWQ22_08110	COG0628	permease
AWQ22_08120	COG0745	RESPONSE REGULATOR receiver
AWQ22_08125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ22_08155	COG0247	lactate metabolic process
AWQ22_08160	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWQ22_08165	COG0126	phosphoglycerate kinase activity
AWQ22_08170	COG0589	response to stress
AWQ22_08175	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ22_08185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AWQ22_08205	COG0454	-acetyltransferase
AWQ22_08225	COG2890	protein-(glutamine-N5) methyltransferase activity
AWQ22_08280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ22_08285	COG0768	penicillin binding
AWQ22_08290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWQ22_08295	COG0181	hydroxymethylbilane synthase activity
AWQ22_08315	COG3118	belongs to the thioredoxin family
AWQ22_08325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWQ22_08335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ22_08345	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWQ22_08350	COG2346	COG2346, Truncated hemoglobins
AWQ22_08355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWQ22_08365	COG2161	toxin-antitoxin pair type II binding
AWQ22_08370	COG4115	mRNA cleavage
AWQ22_08375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ22_08385	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ22_08390	COG0724	RNA recognition motif
AWQ22_08395	COG0174	glutamine synthetase
AWQ22_08405	COG0583	DNA-binding transcription factor activity
AWQ22_08430	COG2385	sporulation resulting in formation of a cellular spore
AWQ22_08430	COG2247	cell wall binding repeat
AWQ22_08440	COG0217	transcriptional regulatory protein
AWQ22_08445	COG2205	protein histidine kinase activity
AWQ22_08450	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWQ22_08460	COG1196	nuclear chromosome segregation
AWQ22_08460	COG0739	heme binding
AWQ22_08460	COG0741	lytic transglycosylase activity
AWQ22_08470	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AWQ22_08510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ22_08515	COG1045	serine acetyltransferase
AWQ22_08525	COG1120	ATPase activity
AWQ22_08530	COG0735	belongs to the Fur family
AWQ22_08545	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ22_08550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWQ22_08555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ22_08565	COG0442	prolyl-tRNA aminoacylation
AWQ22_08570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ22_08575	COG0469	pyruvate kinase activity
AWQ22_08610	COG0515	serine threonine protein kinase
AWQ22_08620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ22_08640	COG1994	Peptidase M50
AWQ22_08640	COG0517	IMP dehydrogenase activity
AWQ22_08660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWQ22_08670	COG4372	Transposase
AWQ22_08680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWQ22_08685	COG0275	rRNA processing
AWQ22_08700	COG0116	Belongs to the methyltransferase superfamily
AWQ22_08705	COG0515	serine threonine protein kinase
AWQ22_08710	COG1049	propionate catabolic process, 2-methylcitrate cycle
AWQ22_08755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWQ22_08760	COG0314	molybdopterin synthase activity
AWQ22_08770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWQ22_08780	COG0495	leucyl-tRNA aminoacylation
AWQ22_08805	COG2310	stress, protein
AWQ22_08810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ22_08815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ22_08825	COG0328	RNA-DNA hybrid ribonuclease activity
AWQ22_08830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ22_08835	COG0704	Plays a role in the regulation of phosphate uptake
AWQ22_08840	COG0009	L-threonylcarbamoyladenylate synthase
AWQ22_08845	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AWQ22_08865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWQ22_08870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWQ22_08885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWQ22_08890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ22_08890	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AWQ22_08895	COG0842	Transport permease protein
AWQ22_08905	COG1131	(ABC) transporter
AWQ22_08910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ22_08940	COG0515	serine threonine protein kinase
AWQ22_08940	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ22_08945	COG0012	GTP binding
AWQ22_08955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWQ22_08970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ22_08975	COG1121	(ABC) transporter
AWQ22_08990	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ22_08990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ22_08995	COG0484	heat shock protein binding
AWQ22_09000	COG3174	membrane
AWQ22_09010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWQ22_09015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AWQ22_09020	COG0426	domain, Protein
AWQ22_09020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ22_09025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWQ22_09035	COG0375	protein maturation
AWQ22_09040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ22_09050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ22_09055	COG1116	anion transmembrane transporter activity
AWQ22_09060	COG0010	Belongs to the arginase family
AWQ22_09070	COG0113	porphobilinogen synthase activity
AWQ22_09090	COG0170	dolichyl monophosphate biosynthetic process
AWQ22_09110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWQ22_09115	COG0512	Glutamine amidotransferase of anthranilate synthase
AWQ22_09115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ22_09120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWQ22_09125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWQ22_09135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ22_09205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWQ22_09210	COG2226	methyltransferase
AWQ22_09215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWQ22_09215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ22_09220	COG1489	DNA binding
AWQ22_09260	COG2814	Major facilitator Superfamily
AWQ22_09270	COG4451	ribulose bisphosphate carboxylase, small
AWQ22_09280	COG1850	ribulose-bisphosphate carboxylase activity
AWQ22_09290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWQ22_09290	COG4451	ribulose bisphosphate carboxylase, small
AWQ22_09295	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AWQ22_09300	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ22_09305	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ22_09310	COG0659	secondary active sulfate transmembrane transporter activity
AWQ22_09315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ22_09320	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_09330	COG1166	arginine decarboxylase activity
AWQ22_09345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ22_09350	COG0719	Fe-S assembly protein
AWQ22_09355	COG0396	ATPase activity
AWQ22_09360	COG0719	Fe-S assembly protein
AWQ22_09385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ22_09410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWQ22_09420	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWQ22_09425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ22_09425	COG2022	thiamine diphosphate biosynthetic process
AWQ22_09435	COG0408	coproporphyrinogen oxidase activity
AWQ22_09440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWQ22_09445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AWQ22_09455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ22_09460	COG0861	Integral membrane protein TerC family
AWQ22_09470	COG2045	Belongs to the ComB family
AWQ22_09485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWQ22_09510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ22_09515	COG0793	Belongs to the peptidase S41A family
AWQ22_09520	COG2052	Domain of unknown function (DUF370)
AWQ22_09525	COG0194	GDP metabolic process
AWQ22_09530	COG0740	serine-type endopeptidase activity
AWQ22_09540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWQ22_09550	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AWQ22_09575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ22_09580	COG0697	spore germination
AWQ22_09600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ22_09610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWQ22_09615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWQ22_09620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWQ22_09635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWQ22_09640	COG2385	sporulation resulting in formation of a cellular spore
AWQ22_09655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWQ22_09670	COG0842	Transport permease protein
AWQ22_09670	COG1131	(ABC) transporter
AWQ22_09670	COG1716	ATPase activity
AWQ22_09680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWQ22_09690	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ22_09695	COG3932	Exopolysaccharide synthesis, ExoD
AWQ22_09705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWQ22_09710	COG0859	PFAM glycosyl transferase family 9
AWQ22_09715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWQ22_09735	COG0723	plastoquinol--plastocyanin reductase activity
AWQ22_09740	COG3258	Cytochrome c
AWQ22_09745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ22_09760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ22_09770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWQ22_09775	COG1799	cell septum assembly
AWQ22_09780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWQ22_09785	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AWQ22_09790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWQ22_09800	COG0037	tRNA processing
AWQ22_09805	COG1191	sigma factor activity
AWQ22_09810	COG0484	heat shock protein binding
AWQ22_09835	COG1801	Protein of unknown function DUF72
AWQ22_09850	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ22_09850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ22_09855	COG1562	ergosterol biosynthetic process
AWQ22_09865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ22_09885	COG0023	Translation Initiation Factor
AWQ22_09910	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AWQ22_09915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ22_09935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ22_09940	COG5002	protein histidine kinase activity
AWQ22_09955	COG2197	response regulator
AWQ22_09960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWQ22_09965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWQ22_09970	COG0052	Belongs to the universal ribosomal protein uS2 family
AWQ22_09975	COG2885	chlorophyll binding
AWQ22_09980	COG2885	chlorophyll binding
AWQ22_09990	COG0628	permease
AWQ22_09995	COG0776	regulation of translation
AWQ22_10005	COG0390	transport system, permease component
AWQ22_10010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWQ22_10030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_10040	COG2244	polysaccharide biosynthetic process
AWQ22_10045	COG0438	transferase activity, transferring glycosyl groups
AWQ22_10050	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ22_10060	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ22_10080	COG1666	GTP binding
AWQ22_10085	COG1575	Belongs to the MenA family. Type 1 subfamily
AWQ22_10090	COG0131	Imidazoleglycerol-phosphate dehydratase
AWQ22_10110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ22_10115	COG5398	heme oxygenase
AWQ22_10120	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ22_10125	COG1733	regulation of RNA biosynthetic process
AWQ22_10130	COG0726	polysaccharide deacetylase
AWQ22_10140	COG0411	ABC transporter
AWQ22_10145	COG0288	reversible hydration of carbon dioxide
AWQ22_10165	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_10170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ22_10175	COG1420	regulation of RNA biosynthetic process
AWQ22_10180	COG1971	Probably functions as a manganese efflux pump
AWQ22_10200	COG0237	dephospho-CoA kinase activity
AWQ22_10200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ22_10205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ22_10220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ22_10225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ22_10235	COG2363	Small membrane protein
AWQ22_10245	COG0312	modulator of DNA gyrase
AWQ22_10250	COG0747	negative chemotaxis
AWQ22_10265	COG0366	Alpha amylase catalytic
AWQ22_10270	COG3769	mannosylglycerate metabolic process
AWQ22_10320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AWQ22_10320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWQ22_10330	COG0395	ABC-type sugar transport system, permease component
AWQ22_10335	COG1175	transmembrane transport
AWQ22_10340	COG1653	transport
AWQ22_10345	COG3842	ATPase activity
AWQ22_10355	COG1027	Aspartate ammonia-lyase
AWQ22_10365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ22_10370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ22_10375	COG0085	RNA polymerase activity
AWQ22_10380	COG0084	hydrolase, TatD family'
AWQ22_10385	COG0268	Binds directly to 16S ribosomal RNA
AWQ22_10435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ22_10445	COG0051	transcription antitermination factor activity, RNA binding
AWQ22_10450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWQ22_10455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ22_10460	COG0049	tRNA binding
AWQ22_10465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWQ22_10470	COG0316	Belongs to the HesB IscA family
AWQ22_10480	COG0590	tRNA wobble adenosine to inosine editing
AWQ22_10485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ22_10490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AWQ22_10495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWQ22_10500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ22_10510	COG1597	lipid kinase activity
AWQ22_10520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ22_10540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ22_10560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ22_10580	COG4149	molybdate abc transporter
AWQ22_10590	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWQ22_10605	COG0039	L-malate dehydrogenase activity
AWQ22_10630	COG0418	dihydroorotase activity
AWQ22_10645	COG5002	protein histidine kinase activity
AWQ22_10655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWQ22_10660	COG0210	DNA helicase
AWQ22_10665	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ22_10670	COG1131	(ABC) transporter
AWQ22_10675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ22_10690	COG1595	DNA-templated transcription, initiation
AWQ22_10710	COG1252	NADH dehydrogenase
AWQ22_10720	COG0829	nickel cation binding
AWQ22_10740	COG0439	Biotin carboxylase
AWQ22_10760	COG0460	homoserine dehydrogenase
AWQ22_10780	COG4636	protein conserved in cyanobacteria
AWQ22_10830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWQ22_10840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWQ22_10845	COG0589	response to stress
AWQ22_10865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ22_10880	COG4636	protein conserved in cyanobacteria
AWQ22_10890	COG0443	Heat shock 70 kDa protein
AWQ22_10895	COG0484	heat shock protein binding
AWQ22_10900	COG0564	pseudouridine synthase activity
AWQ22_10905	COG0668	transmembrane transport
AWQ22_10925	COG5001	Diguanylate cyclase
AWQ22_10925	COG3300	MHYT domain
AWQ22_10975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ22_10980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWQ22_10985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWQ22_11005	COG0463	Glycosyl transferase, family 2
AWQ22_11010	COG0003	Pfam Anion-transporting ATPase
AWQ22_11015	COG0436	Aminotransferase
AWQ22_11020	COG1132	(ABC) transporter
AWQ22_11030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ22_11045	COG0772	Belongs to the SEDS family
AWQ22_11050	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWQ22_11100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWQ22_11110	COG0004	ammonium transporteR
AWQ22_11125	COG0237	dephospho-CoA kinase activity
AWQ22_11130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ22_11135	COG1413	lyase activity
AWQ22_11140	COG1413	lyase activity
AWQ22_11155	COG0824	Thioesterase
AWQ22_11165	COG0537	adenosine 5'-monophosphoramidase activity
AWQ22_11175	COG1131	(ABC) transporter
AWQ22_11215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ22_11220	COG1131	(ABC) transporter
AWQ22_11235	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWQ22_11265	COG1192	Involved in chromosome partitioning
AWQ22_11300	COG2852	Protein conserved in bacteria
AWQ22_11335	COG0193	aminoacyl-tRNA hydrolase activity
AWQ22_11360	COG0454	-acetyltransferase
AWQ22_11370	COG0556	nucleotide-excision repair
AWQ22_11375	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ22_11420	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AWQ22_11425	COG0569	domain protein
AWQ22_11430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWQ22_11445	COG2205	protein histidine kinase activity
AWQ22_11445	COG3850	Histidine kinase
AWQ22_11445	COG3437	response regulator, receiver
AWQ22_11445	COG4999	Histidine kinase
AWQ22_11465	COG0124	histidyl-tRNA synthetase
AWQ22_11475	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWQ22_11490	COG2267	carboxylic ester hydrolase activity
AWQ22_11495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ22_11505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWQ22_11510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWQ22_11515	COG0573	inorganic phosphate transmembrane transporter activity
AWQ22_11520	COG0581	inorganic phosphate transmembrane transporter activity
AWQ22_11530	COG0802	atpase or kinase
AWQ22_11545	COG0315	cyclic pyranopterin monophosphate synthase activity
AWQ22_11555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ22_11560	COG3152	Membrane
AWQ22_11570	COG3046	protein related to deoxyribodipyrimidine photolyase
AWQ22_11580	COG0768	penicillin binding
AWQ22_11590	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWQ22_11595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ22_11615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWQ22_11625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWQ22_11630	COG1252	NADH dehydrogenase
AWQ22_11655	COG2217	Heavy metal translocating P-type atpase
AWQ22_11660	COG2132	Multicopper oxidase
AWQ22_11670	COG1836	PFAM Integral membrane protein DUF92
AWQ22_11685	COG0673	inositol 2-dehydrogenase activity
AWQ22_11695	COG0633	Ferredoxin
AWQ22_11700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_11705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWQ22_11710	COG0830	nickel cation binding
AWQ22_11725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ22_11740	COG0792	nuclease activity
AWQ22_11755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWQ22_11770	COG0024	Methionine aminopeptidase
AWQ22_11780	COG0598	Magnesium transport protein CorA
AWQ22_11795	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AWQ22_11800	COG0242	peptide deformylase activity
AWQ22_11825	COG0542	response to heat
AWQ22_11830	COG0473	3-isopropylmalate dehydrogenase activity
AWQ22_11840	COG2081	HI0933 family
AWQ22_11850	COG1187	pseudouridine synthase activity
AWQ22_11860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWQ22_11870	COG4106	trans-aconitate 2-methyltransferase activity
AWQ22_11880	COG0539	negative regulation of cytoplasmic translation
AWQ22_11885	COG5001	Diguanylate cyclase
AWQ22_11885	COG3300	MHYT domain
AWQ22_11890	COG2205	protein histidine kinase activity
AWQ22_11900	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ22_11905	COG3118	belongs to the thioredoxin family
AWQ22_11915	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AWQ22_11920	COG0659	secondary active sulfate transmembrane transporter activity
AWQ22_11925	COG0475	glutathione-regulated potassium exporter activity
AWQ22_11930	COG1006	Multisubunit Na H antiporter MnhC subunit
AWQ22_11940	COG0651	ATP synthesis coupled electron transport
AWQ22_11975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ22_11980	COG1056	cytidyltransferase-related domain
AWQ22_11980	COG1051	belongs to the nudix hydrolase family
AWQ22_11985	COG0587	DNA-directed DNA polymerase activity
AWQ22_11995	COG1187	pseudouridine synthase activity
AWQ22_12020	COG2010	Cytochrome c
AWQ22_12030	COG0067	glutamate synthase
AWQ22_12030	COG0069	glutamate synthase activity
AWQ22_12030	COG0070	glutamate synthase
AWQ22_12035	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWQ22_12050	COG1234	tRNA 3'-trailer cleavage
AWQ22_12055	COG0196	riboflavin kinase activity
AWQ22_12060	COG0714	Associated with various cellular activities
AWQ22_12075	COG1473	amidohydrolase
AWQ22_12085	COG1605	Chorismate mutase
AWQ22_12085	COG0077	Prephenate dehydratase
AWQ22_12110	COG1480	7TM receptor with intracellular HD hydrolase
AWQ22_12130	COG0435	Glutathione S-transferase
AWQ22_12145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWQ22_12160	COG0443	Heat shock 70 kDa protein
AWQ22_12175	COG0481	GTPase activity
AWQ22_12180	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AWQ22_12185	COG0589	response to stress
AWQ22_12190	COG0659	secondary active sulfate transmembrane transporter activity
AWQ22_12195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWQ22_12210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWQ22_12225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ22_12240	COG0438	transferase activity, transferring glycosyl groups
AWQ22_12255	COG0832	Belongs to the urease beta subunit family
AWQ22_12260	COG1940	carbohydrate kinase activity
AWQ22_12275	COG0670	Belongs to the BI1 family
AWQ22_12280	COG0825	malonyl-CoA metabolic process
AWQ22_12290	COG0302	gtp cyclohydrolase
AWQ22_12295	COG1902	pentaerythritol trinitrate reductase activity
AWQ22_12310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ22_12345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWQ22_12360	COG0751	glycine-tRNA ligase activity
AWQ22_12365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWQ22_12370	COG0459	protein refolding
AWQ22_12390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWQ22_12395	COG5001	Diguanylate cyclase
AWQ22_12400	COG1970	mechanosensitive ion channel activity
AWQ22_12410	COG1331	Highly conserved protein containing a thioredoxin domain
AWQ22_12425	COG0646	methionine synthase
AWQ22_12425	COG1410	methionine synthase
AWQ22_12435	COG0017	Asparaginyl-tRNA synthetase
AWQ22_12440	COG0431	NADPH-dependent FMN reductase
AWQ22_12455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWQ22_12465	COG0438	transferase activity, transferring glycosyl groups
AWQ22_12475	COG0644	oxidoreductase
AWQ22_12490	COG0575	Belongs to the CDS family
AWQ22_12525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWQ22_12530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWQ22_12555	COG0612	Peptidase, M16
AWQ22_12565	COG0432	Pfam Uncharacterised protein family UPF0047
AWQ22_12580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ22_12585	COG1121	(ABC) transporter
AWQ22_12600	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ22_12610	COG2205	protein histidine kinase activity
AWQ22_12610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ22_12615	COG0505	Belongs to the CarA family
AWQ22_12620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ22_12620	COG0758	DNA mediated transformation
AWQ22_12625	COG1840	ABC-type Fe3 transport system, periplasmic component
AWQ22_12630	COG5398	heme oxygenase
AWQ22_12640	COG2268	Band 7 protein
AWQ22_12665	COG0484	heat shock protein binding
AWQ22_12670	COG1690	Belongs to the RtcB family
AWQ22_12675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWQ22_12680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWQ22_12690	COG0300	oxidoreductase activity
AWQ22_12690	COG3000	fatty acid hydroxylase
AWQ22_12705	COG3411	Ferredoxin
AWQ22_12710	COG2197	response regulator
AWQ22_12720	COG1546	Belongs to the CinA family
AWQ22_12720	COG1058	Belongs to the CinA family
AWQ22_12725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWQ22_12765	COG0745	RESPONSE REGULATOR receiver
AWQ22_12775	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ22_12790	COG0616	signal peptide processing
AWQ22_12795	COG0697	spore germination
AWQ22_12805	COG0649	NAD binding
AWQ22_12810	COG0571	ribonuclease III activity
AWQ22_12815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ22_12825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ22_12830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWQ22_12830	COG1754	DNA topoisomerase type I activity
AWQ22_12835	COG1007	ATP synthesis coupled electron transport
AWQ22_12855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWQ22_12860	COG0601	transmembrane transport
AWQ22_12895	COG2211	Major facilitator Superfamily
AWQ22_12900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ22_12905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWQ22_12910	COG0406	alpha-ribazole phosphatase activity
AWQ22_12915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWQ22_12930	COG0640	Transcriptional regulator
AWQ22_12935	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AWQ22_12955	COG1053	succinate dehydrogenase
AWQ22_12965	COG3854	ATPases associated with a variety of cellular activities
AWQ22_12970	COG2373	Large extracellular alpha-helical protein
AWQ22_12985	COG5002	protein histidine kinase activity
AWQ22_12995	COG0612	Peptidase, M16
AWQ22_13010	COG0668	transmembrane transport
AWQ22_13020	COG3668	Plasmid stabilization system
AWQ22_13025	COG1193	negative regulation of DNA recombination
AWQ22_13055	COG3300	MHYT domain
AWQ22_13055	COG5001	Diguanylate cyclase
AWQ22_13060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ22_13065	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ22_13065	COG3347	Dehydrogenase
AWQ22_13080	COG0484	heat shock protein binding
AWQ22_13115	COG0840	transmembrane signaling receptor activity
AWQ22_13115	COG2203	Gaf domain
AWQ22_13130	COG0784	Response regulator, receiver
AWQ22_13135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ22_13140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWQ22_13145	COG3693	PFAM glycoside hydrolase, family 10
AWQ22_13180	COG2217	Heavy metal translocating P-type atpase
AWQ22_13190	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ22_13195	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ22_13200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ22_13240	COG2062	phosphohistidine phosphatase, SixA
AWQ22_13245	COG0372	Belongs to the citrate synthase family
AWQ22_13255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ22_13270	COG0419	ATPase involved in DNA repair
AWQ22_13300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ22_13305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWQ22_13325	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AWQ22_13345	COG4948	Mandelate Racemase Muconate Lactonizing
AWQ22_13355	COG3437	response regulator, receiver
AWQ22_13355	COG4999	Histidine kinase
AWQ22_13355	COG3850	Histidine kinase
AWQ22_13355	COG2205	protein histidine kinase activity
AWQ22_13370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ22_13395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWQ22_13400	COG2200	EAL domain
AWQ22_13405	COG0523	cobalamin synthesis protein
AWQ22_13420	COG3128	pkhd-type hydroxylase
AWQ22_13445	COG2193	ferroxidase activity
AWQ22_13450	COG0572	uridine kinase
AWQ22_13460	COG0415	Belongs to the DNA photolyase family
AWQ22_13470	COG0596	Alpha beta hydrolase
AWQ22_13505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ22_13540	COG2319	Wd-40 repeat
AWQ22_13540	COG4249	Peptidase C14 caspase catalytic subunit p20
AWQ22_13570	COG0589	response to stress
AWQ22_13575	COG1672	PFAM Archaeal ATPase
AWQ22_13580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWQ22_13590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ22_13595	COG0330	HflC and HflK could
AWQ22_13620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWQ22_13625	COG2267	carboxylic ester hydrolase activity
AWQ22_13630	COG0440	acetolactate synthase activity
AWQ22_13640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ22_13655	COG0482	sulfurtransferase activity
AWQ22_13660	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AWQ22_13675	COG0237	dephospho-CoA kinase activity
AWQ22_13695	COG1741	Belongs to the pirin family
AWQ22_13715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWQ22_13735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWQ22_13740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AWQ22_13745	COG1122	ATPase activity
AWQ22_13775	COG3266	domain, Protein
AWQ22_13775	COG0515	serine threonine protein kinase
AWQ22_13790	COG0668	transmembrane transport
AWQ22_13795	COG2226	methyltransferase
AWQ22_13810	COG3012	SEC-C Motif Domain Protein
AWQ22_13820	COG0709	Synthesizes selenophosphate from selenide and ATP
AWQ22_13835	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_13840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_13845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ22_13850	COG2319	Wd-40 repeat
AWQ22_13865	COG0004	ammonium transporteR
AWQ22_13870	COG3239	Fatty acid desaturase
AWQ22_13880	COG2119	membrane
AWQ22_13890	COG1473	amidohydrolase
AWQ22_13900	COG3300	MHYT domain
AWQ22_13900	COG5001	Diguanylate cyclase
AWQ22_13905	COG2304	oxidoreductase activity
AWQ22_13910	COG2501	S4 domain
AWQ22_13915	COG0412	Dienelactone hydrolase
AWQ22_13930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWQ22_13935	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AWQ22_13945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWQ22_13955	COG1012	belongs to the aldehyde dehydrogenase family
AWQ22_13975	COG0686	Belongs to the AlaDH PNT family
AWQ22_13985	COG0582	viral genome integration into host DNA
AWQ22_14090	COG1196	nuclear chromosome segregation
AWQ22_14090	COG0741	lytic transglycosylase activity
AWQ22_14090	COG0739	heme binding
AWQ22_14175	COG0625	glutathione transferase activity
AWQ22_14180	COG0343	queuine tRNA-ribosyltransferase activity
AWQ22_14190	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AWQ22_14225	COG1132	(ABC) transporter
AWQ22_14230	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWQ22_14235	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ22_14245	COG0552	protein localization to endoplasmic reticulum
AWQ22_14250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ22_14255	COG0415	Belongs to the DNA photolyase family
AWQ22_14260	COG0028	Belongs to the TPP enzyme family
AWQ22_14275	COG4968	Prepilin-type N-terminal cleavage methylation domain
AWQ22_14280	COG4968	Prepilin-type N-terminal cleavage methylation domain
AWQ22_14285	COG2852	Protein conserved in bacteria
AWQ22_14290	COG0137	argininosuccinate synthase activity
AWQ22_14295	COG1234	tRNA 3'-trailer cleavage
AWQ22_14315	COG0312	modulator of DNA gyrase
AWQ22_14320	COG2154	pterin-4-alpha-carbinolamine dehydratase
AWQ22_14325	COG3659	wide pore channel activity
AWQ22_14330	COG2084	Dehydrogenase
AWQ22_14335	COG5001	Diguanylate cyclase
AWQ22_14335	COG4251	negative regulation of phosphorylation
AWQ22_14335	COG2203	Gaf domain
AWQ22_14335	COG3706	GGDEF domain
AWQ22_14340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ22_14360	COG1543	Belongs to the glycosyl hydrolase 57 family
AWQ22_14370	COG1950	PFAM Membrane protein of
AWQ22_14380	COG3339	Conserved Protein
AWQ22_14390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWQ22_14395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWQ22_14410	COG4956	integral membrane protein (PIN domain superfamily)
AWQ22_14415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ22_14420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ22_14435	COG4251	negative regulation of phosphorylation
AWQ22_14470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWQ22_14485	COG2211	Major facilitator Superfamily
AWQ22_14520	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AWQ22_14525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWQ22_14530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWQ22_14535	COG0135	phosphoribosylanthranilate isomerase activity
AWQ22_14540	COG0746	molybdenum cofactor guanylyltransferase activity
AWQ22_14550	COG1672	PFAM Archaeal ATPase
AWQ22_14550	COG2319	Wd-40 repeat
AWQ22_14585	COG0668	transmembrane transport
AWQ22_14610	COG3954	Phosphoribulokinase
AWQ22_14615	COG0277	FAD linked oxidase domain protein
AWQ22_14640	COG4251	negative regulation of phosphorylation
AWQ22_14640	COG5001	Diguanylate cyclase
AWQ22_14640	COG3706	GGDEF domain
AWQ22_14640	COG2203	Gaf domain
AWQ22_14645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWQ22_14655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ22_14660	COG0730	response to heat
AWQ22_14675	COG2304	oxidoreductase activity
AWQ22_14680	COG0215	cysteine-tRNA ligase activity
AWQ22_14715	COG1061	Type III restriction enzyme res subunit
AWQ22_14770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AWQ22_14800	COG0732	type I restriction modification DNA specificity domain
AWQ22_14815	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AWQ22_14840	COG1061	Type III restriction enzyme res subunit
AWQ22_14900	COG1598	PFAM Uncharacterised protein family UPF0150
AWQ22_14905	COG1192	Involved in chromosome partitioning
AWQ22_14905	COG1192	Involved in chromosome partitioning
AWQ22_15030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWQ22_15035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWQ22_15115	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWQ22_15120	COG0723	plastoquinol--plastocyanin reductase activity
AWQ22_15130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ22_15135	COG1120	ATPase activity
AWQ22_15150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ22_15180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ22_15185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ22_15200	COG4607	ABC-type enterochelin transport system periplasmic component
AWQ22_15215	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AWQ22_15220	COG4774	siderophore transport
AWQ22_15225	COG2169	Transcriptional regulator
AWQ22_15225	COG1917	Cupin 2, conserved barrel domain protein
AWQ22_15230	COG1132	(ABC) transporter
AWQ22_15240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ22_15255	COG2124	cytochrome p450
AWQ22_15265	COG1132	(ABC) transporter
AWQ22_15375	COG0113	porphobilinogen synthase activity
AWQ22_15380	COG0302	gtp cyclohydrolase
AWQ22_15390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWQ22_15410	COG0405	Gamma-glutamyltransferase
AWQ22_15420	COG0848	biopolymer transport protein
AWQ22_15425	COG0811	peptide transport
AWQ22_15435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ22_15440	COG2304	oxidoreductase activity
AWQ22_15445	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWQ22_15455	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ22_15465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWQ22_15495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ22_15505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ22_15510	COG3447	MASE1 domain protein
AWQ22_15510	COG5002	protein histidine kinase activity
AWQ22_15510	COG5001	Diguanylate cyclase
AWQ22_15515	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AWQ22_15520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AWQ22_15535	COG0745	RESPONSE REGULATOR receiver
AWQ22_15540	COG3850	Histidine kinase
AWQ22_15540	COG5002	protein histidine kinase activity
AWQ22_15560	COG0398	Pfam SNARE associated Golgi protein
AWQ22_15565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWQ22_15635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ22_15640	COG3932	Exopolysaccharide synthesis, ExoD
AWQ22_15645	COG1116	anion transmembrane transporter activity
AWQ22_15645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ22_15650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ22_15650	COG1116	anion transmembrane transporter activity
AWQ22_15655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ22_15665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWQ22_15675	COG3239	Fatty acid desaturase
AWQ22_15680	COG2226	methyltransferase
AWQ22_15715	COG0076	glutamate decarboxylase activity
AWQ22_15730	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AWQ22_15770	COG2361	Protein of unknown function DUF86
AWQ22_15855	COG2887	Belongs to the helicase family. UvrD subfamily
AWQ22_15885	COG1475	DNA binding
AWQ22_15890	COG1192	Involved in chromosome partitioning
AWQ22_15925	COG1569	PIN domain
AWQ22_15950	COG4942	peptidase
AWQ22_15950	COG1388	LysM domain
AWQ22_16055	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWQ22_16140	COG4680	protein conserved in bacteria
AWQ22_16205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily