locus-tag	class	description
AWQ23_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWQ23_00030	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AWQ23_00035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWQ23_00040	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AWQ23_00040	COG0662	Cupin 2, conserved barrel domain protein
AWQ23_00050	COG1830	Aldolase
AWQ23_00055	COG4636	protein conserved in cyanobacteria
AWQ23_00090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_00100	COG0742	ribosomal rna small subunit methyltransferase
AWQ23_00125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWQ23_00130	COG0351	phosphomethylpyrimidine kinase
AWQ23_00135	COG1160	GTP binding
AWQ23_00150	COG0572	uridine kinase
AWQ23_00155	COG1280	lysine exporter protein (LysE YggA)
AWQ23_00165	COG0783	Belongs to the Dps family
AWQ23_00175	COG1253	flavin adenine dinucleotide binding
AWQ23_00185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWQ23_00195	COG0180	Tryptophanyl-tRNA synthetase
AWQ23_00205	COG0384	phenazine biosynthesis protein PhzF
AWQ23_00210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_00235	COG0784	Response regulator, receiver
AWQ23_00250	COG0840	transmembrane signaling receptor activity
AWQ23_00250	COG2203	Gaf domain
AWQ23_00270	COG0511	ligase activity, forming carbon-carbon bonds
AWQ23_00275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWQ23_00285	COG1487	ribonuclease activity
AWQ23_00300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWQ23_00310	COG0494	nUDIX hydrolase
AWQ23_00315	COG0571	ribonuclease III activity
AWQ23_00330	COG0737	Belongs to the 5'-nucleotidase family
AWQ23_00340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AWQ23_00375	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ23_00390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWQ23_00495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWQ23_00500	COG0148	phosphopyruvate hydratase activity
AWQ23_00505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWQ23_00510	COG1472	Belongs to the glycosyl hydrolase 3 family
AWQ23_00525	COG3937	granule-associated protein
AWQ23_00535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ23_00550	COG3773	Cell wall hydrolase
AWQ23_00550	COG3409	Peptidoglycan-binding domain 1 protein
AWQ23_00555	COG0612	Peptidase, M16
AWQ23_00560	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWQ23_00560	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWQ23_00595	COG0083	homoserine kinase activity
AWQ23_00615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ23_00620	COG0456	acetyltransferase
AWQ23_00630	COG0019	diaminopimelate decarboxylase activity
AWQ23_00635	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWQ23_00640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWQ23_00660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWQ23_00670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWQ23_00680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWQ23_00685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ23_00690	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ23_00695	COG2010	Cytochrome c
AWQ23_00715	COG0656	L-ascorbic acid biosynthetic process
AWQ23_00720	COG0386	Belongs to the glutathione peroxidase family
AWQ23_00730	COG0629	single-stranded DNA binding
AWQ23_00735	COG0668	transmembrane transport
AWQ23_00740	COG4172	Belongs to the ABC transporter superfamily
AWQ23_00745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWQ23_00750	COG0494	nUDIX hydrolase
AWQ23_00755	COG1160	GTP binding
AWQ23_00760	COG3268	Saccharopine dehydrogenase
AWQ23_00765	COG2116	formate transmembrane transporter activity
AWQ23_00770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ23_00780	COG1959	2 iron, 2 sulfur cluster binding
AWQ23_00795	COG0789	Transcriptional regulator
AWQ23_00805	COG1175	transmembrane transport
AWQ23_00810	COG0728	peptidoglycan biosynthetic process
AWQ23_00820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWQ23_00830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AWQ23_00845	COG0542	response to heat
AWQ23_00860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ23_00900	COG0459	protein refolding
AWQ23_00905	COG5002	protein histidine kinase activity
AWQ23_00905	COG0784	Response regulator, receiver
AWQ23_00905	COG2205	protein histidine kinase activity
AWQ23_00920	COG0737	Belongs to the 5'-nucleotidase family
AWQ23_00925	COG0668	transmembrane transport
AWQ23_00945	COG0756	dUTP diphosphatase activity
AWQ23_00965	COG3239	Fatty acid desaturase
AWQ23_00980	COG0205	6-phosphofructokinase activity
AWQ23_00995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ23_01005	COG1131	(ABC) transporter
AWQ23_01010	COG2010	Cytochrome c
AWQ23_01025	COG2124	cytochrome p450
AWQ23_01030	COG0583	DNA-binding transcription factor activity
AWQ23_01035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ23_01040	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_01050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ23_01055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWQ23_01055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWQ23_01060	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWQ23_01065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWQ23_01085	COG4935	Belongs to the peptidase S8 family
AWQ23_01085	COG1404	Belongs to the peptidase S8 family
AWQ23_01095	COG0457	Tetratricopeptide repeat
AWQ23_01095	COG0463	Glycosyl transferase, family 2
AWQ23_01110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ23_01135	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWQ23_01140	COG4636	protein conserved in cyanobacteria
AWQ23_01145	COG0804	urea catabolic process
AWQ23_01170	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AWQ23_01180	COG3259	Nickel-dependent hydrogenase
AWQ23_01190	COG0375	protein maturation
AWQ23_01195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ23_01200	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AWQ23_01205	COG0298	carbon dioxide binding
AWQ23_01225	COG1490	D-aminoacyl-tRNA deacylase activity
AWQ23_01245	COG0793	Belongs to the peptidase S41A family
AWQ23_01255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ23_01260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ23_01265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ23_01270	COG0745	RESPONSE REGULATOR receiver
AWQ23_01280	COG2003	Belongs to the UPF0758 family
AWQ23_01285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWQ23_01290	COG0312	modulator of DNA gyrase
AWQ23_01310	COG0316	Belongs to the HesB IscA family
AWQ23_01315	COG0569	domain protein
AWQ23_01320	COG1773	rubredoxin
AWQ23_01325	COG4447	cellulose binding
AWQ23_01340	COG3977	Valine--pyruvate aminotransferase
AWQ23_01350	COG0322	excinuclease ABC activity
AWQ23_01365	COG1131	(ABC) transporter
AWQ23_01375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWQ23_01390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ23_01400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWQ23_01410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWQ23_01410	COG0574	Belongs to the PEP-utilizing enzyme family
AWQ23_01435	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AWQ23_01440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWQ23_01460	COG1968	undecaprenyl-diphosphatase activity
AWQ23_01470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWQ23_01480	COG0516	GMP reductase activity
AWQ23_01505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ23_01510	COG1834	amidinotransferase
AWQ23_01515	COG0724	RNA recognition motif
AWQ23_01520	COG2239	Acts as a magnesium transporter
AWQ23_01550	COG0352	thiamine-phosphate diphosphorylase activity
AWQ23_01555	COG0602	queuosine metabolic process
AWQ23_01560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWQ23_01565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ23_01570	COG0589	response to stress
AWQ23_01570	COG0475	glutathione-regulated potassium exporter activity
AWQ23_01580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWQ23_01590	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AWQ23_01595	COG4251	negative regulation of phosphorylation
AWQ23_01605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ23_01615	COG0436	Aminotransferase
AWQ23_01620	COG3118	belongs to the thioredoxin family
AWQ23_01625	COG1842	Phage shock protein A
AWQ23_01630	COG4251	negative regulation of phosphorylation
AWQ23_01635	COG0133	tryptophan synthase activity
AWQ23_01660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWQ23_01665	COG0783	Belongs to the Dps family
AWQ23_01685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWQ23_01690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWQ23_01700	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWQ23_01710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWQ23_01725	COG0673	inositol 2-dehydrogenase activity
AWQ23_01735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWQ23_01740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWQ23_01745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWQ23_01755	COG0450	alkyl hydroperoxide reductase
AWQ23_01760	COG1555	photosystem II stabilization
AWQ23_01770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWQ23_01775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWQ23_01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWQ23_01785	COG1032	radical SAM domain protein
AWQ23_01795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AWQ23_01800	COG1640	4-alpha-glucanotransferase
AWQ23_01810	COG1192	Involved in chromosome partitioning
AWQ23_01830	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ23_01835	COG0346	lactoylglutathione lyase activity
AWQ23_01840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ23_01845	COG4953	penicillin-binding protein 1C
AWQ23_01855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ23_01865	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWQ23_01865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWQ23_01870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ23_01875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWQ23_01885	COG0517	IMP dehydrogenase activity
AWQ23_01885	COG0516	GMP reductase activity
AWQ23_01895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_01905	COG0509	glycine decarboxylation via glycine cleavage system
AWQ23_01910	COG0006	proline dipeptidase activity
AWQ23_01915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWQ23_01920	COG0484	heat shock protein binding
AWQ23_01930	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AWQ23_01970	COG0606	chelatase, subunit chli
AWQ23_01990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ23_01995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWQ23_02000	COG0157	Belongs to the NadC ModD family
AWQ23_02025	COG2208	phosphoserine phosphatase activity
AWQ23_02030	COG1216	Glycosyl transferase, family 2
AWQ23_02035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWQ23_02045	COG2010	Cytochrome c
AWQ23_02065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ23_02085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ23_02095	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWQ23_02100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ23_02110	COG0752	glycyl-tRNA synthetase alpha subunit
AWQ23_02125	COG1214	PFAM Peptidase M22, glycoprotease
AWQ23_02130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWQ23_02145	COG1606	tRNA processing
AWQ23_02180	COG0285	dihydrofolate synthase activity
AWQ23_02210	COG1132	(ABC) transporter
AWQ23_02215	COG2089	acid synthase
AWQ23_02240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWQ23_02245	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AWQ23_02250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWQ23_02255	COG1086	Polysaccharide biosynthesis protein
AWQ23_02260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWQ23_02275	COG0457	Tetratricopeptide repeat
AWQ23_02280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWQ23_02285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ23_02285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ23_02290	COG2205	protein histidine kinase activity
AWQ23_02290	COG3437	response regulator, receiver
AWQ23_02290	COG4999	Histidine kinase
AWQ23_02290	COG3850	Histidine kinase
AWQ23_02300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWQ23_02305	COG0542	response to heat
AWQ23_02310	COG1192	Involved in chromosome partitioning
AWQ23_02320	COG0339	signal peptide processing
AWQ23_02325	COG0308	aminopeptidase N
AWQ23_02330	COG0673	inositol 2-dehydrogenase activity
AWQ23_02365	COG0360	Binds together with S18 to 16S ribosomal RNA
AWQ23_02375	COG0747	negative chemotaxis
AWQ23_02380	COG0515	serine threonine protein kinase
AWQ23_02380	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ23_02385	COG0072	phenylalanine-tRNA ligase activity
AWQ23_02385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ23_02395	COG4636	protein conserved in cyanobacteria
AWQ23_02400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ23_02405	COG0497	DNA recombination
AWQ23_02410	COG0676	glucose-6-phosphate 1-epimerase activity
AWQ23_02415	COG0631	protein serine/threonine phosphatase activity
AWQ23_02420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ23_02425	COG3937	granule-associated protein
AWQ23_02430	COG0066	3-isopropylmalate dehydratase activity
AWQ23_02435	COG0720	synthase
AWQ23_02440	COG1070	Carbohydrate kinase
AWQ23_02445	COG0515	serine threonine protein kinase
AWQ23_02450	COG2211	Major facilitator Superfamily
AWQ23_02455	COG3659	wide pore channel activity
AWQ23_02480	COG3781	membrane
AWQ23_02485	COG0668	transmembrane transport
AWQ23_02500	COG2308	Evidence 4 Homologs of previously reported genes of
AWQ23_02520	COG0347	Belongs to the P(II) protein family
AWQ23_02530	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWQ23_02535	COG0443	Heat shock 70 kDa protein
AWQ23_02540	COG0612	Peptidase, M16
AWQ23_02560	COG0058	SHG alpha-glucan phosphorylase activity
AWQ23_02570	COG1994	Peptidase M50
AWQ23_02570	COG0517	IMP dehydrogenase activity
AWQ23_02580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWQ23_02585	COG0745	RESPONSE REGULATOR receiver
AWQ23_02595	COG0140	phosphoribosyl-ATP diphosphatase activity
AWQ23_02595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWQ23_02600	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWQ23_02605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWQ23_02615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ23_02620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWQ23_02640	COG0745	RESPONSE REGULATOR receiver
AWQ23_02645	COG1126	abc transporter atp-binding protein
AWQ23_02685	COG1943	Transposase
AWQ23_02695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ23_02695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWQ23_02715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWQ23_02720	COG0436	Aminotransferase
AWQ23_02725	COG0850	regulation of cytokinetic process
AWQ23_02730	COG2894	cell division
AWQ23_02735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AWQ23_02745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWQ23_02765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWQ23_02770	COG0671	phosphoesterase, PA-phosphatase related
AWQ23_02775	COG0612	Peptidase, M16
AWQ23_02780	COG2226	methyltransferase
AWQ23_02790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWQ23_02795	COG0416	fatty acid biosynthetic process
AWQ23_02815	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ23_02830	COG4636	protein conserved in cyanobacteria
AWQ23_02835	COG1215	transferase activity, transferring glycosyl groups
AWQ23_02860	COG0484	heat shock protein binding
AWQ23_02885	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWQ23_02890	COG0271	Belongs to the BolA IbaG family
AWQ23_02900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ23_02905	COG0613	PHP domain protein
AWQ23_02910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWQ23_02920	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWQ23_02925	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWQ23_02930	COG0235	Class ii aldolase
AWQ23_02945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWQ23_02950	COG0450	alkyl hydroperoxide reductase
AWQ23_02970	COG0159	tryptophan synthase activity
AWQ23_02980	COG4243	Vitamin k epoxide reductase
AWQ23_02985	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWQ23_03020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWQ23_03025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWQ23_03030	COG0557	exoribonuclease II activity
AWQ23_03045	COG0475	glutathione-regulated potassium exporter activity
AWQ23_03050	COG2247	cell wall binding repeat
AWQ23_03050	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWQ23_03055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWQ23_03060	COG0142	geranyltranstransferase activity
AWQ23_03080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ23_03085	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWQ23_03105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ23_03110	COG0798	PFAM Bile acid sodium symporter
AWQ23_03115	COG0640	Transcriptional regulator
AWQ23_03125	COG0750	zinc metalloprotease
AWQ23_03135	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWQ23_03140	COG0149	triose-phosphate isomerase activity
AWQ23_03145	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ23_03145	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ23_03155	COG0018	arginyl-trna synthetase
AWQ23_03165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWQ23_03175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWQ23_03185	COG0371	Dehydrogenase
AWQ23_03190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWQ23_03210	COG0284	orotidine-5'-phosphate decarboxylase activity
AWQ23_03210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ23_03215	COG1136	(ABC) transporter
AWQ23_03215	COG0577	efflux transmembrane transporter activity
AWQ23_03225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWQ23_03235	COG2197	response regulator
AWQ23_03245	COG0251	oxidation-reduction process
AWQ23_03250	COG0513	Belongs to the DEAD box helicase family
AWQ23_03255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ23_03260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWQ23_03265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWQ23_03275	COG0483	inositol monophosphate 1-phosphatase activity
AWQ23_03280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ23_03290	COG0488	(ABC) transporter
AWQ23_03300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWQ23_03310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AWQ23_03335	COG4139	cobalamin transport
AWQ23_03350	COG4771	TonB-dependent receptor
AWQ23_03360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ23_03380	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ23_03405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWQ23_03405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWQ23_03410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWQ23_03435	COG0022	dehydrogenase e1 component
AWQ23_03435	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ23_03440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ23_03445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ23_03455	COG2197	response regulator
AWQ23_03460	COG2072	flavoprotein involved in K transport
AWQ23_03485	COG2144	transferase activity, transferring acyl groups
AWQ23_03515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ23_03525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWQ23_03530	COG1022	Amp-dependent synthetase and ligase
AWQ23_03540	COG0287	Prephenate dehydrogenase
AWQ23_03545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWQ23_03555	COG0633	Ferredoxin
AWQ23_03555	COG3217	Mosc domain protein beta barrel domain protein
AWQ23_03560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ23_03575	COG0189	ligase activity
AWQ23_03580	COG4067	protein conserved in archaea
AWQ23_03580	COG0189	ligase activity
AWQ23_03610	COG1162	GTPase activity
AWQ23_03620	COG0484	heat shock protein binding
AWQ23_03625	COG0443	Heat shock 70 kDa protein
AWQ23_03635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWQ23_03665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ23_03670	COG0596	Alpha beta hydrolase
AWQ23_03670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ23_03685	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ23_03710	COG0277	FAD linked oxidase domain protein
AWQ23_03715	COG1132	(ABC) transporter
AWQ23_03720	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWQ23_03725	COG1073	alpha beta
AWQ23_03725	COG3064	Membrane
AWQ23_03725	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWQ23_03730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWQ23_03735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ23_03745	COG0438	transferase activity, transferring glycosyl groups
AWQ23_03755	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWQ23_03775	COG1845	cytochrome c oxidase, subunit III
AWQ23_03780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWQ23_03785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ23_03800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ23_03815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ23_03825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ23_03830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ23_03840	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ23_03845	COG0356	it plays a direct role in the translocation of protons across the membrane
AWQ23_03870	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWQ23_03875	COG0857	belongs to the CobB CobQ family
AWQ23_03885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ23_03895	COG0357	Ribosomal RNA small subunit methyltransferase G
AWQ23_03905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWQ23_03915	COG0779	Required for maturation of 30S ribosomal subunits
AWQ23_03920	COG0195	Participates in both transcription termination and antitermination
AWQ23_03930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWQ23_03935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWQ23_03950	COG3639	organic phosphonate transmembrane transporter activity
AWQ23_03960	COG0515	serine threonine protein kinase
AWQ23_03975	COG0429	hydrolase of the alpha beta-hydrolase fold
AWQ23_03980	COG0488	(ABC) transporter
AWQ23_03990	COG0463	Glycosyl transferase, family 2
AWQ23_03995	COG0681	Belongs to the peptidase S26 family
AWQ23_04015	COG0303	'Molybdopterin
AWQ23_04025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWQ23_04065	COG3659	wide pore channel activity
AWQ23_04080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ23_04090	COG1104	cysteine desulfurase activity
AWQ23_04095	COG1530	ribonuclease E activity
AWQ23_04100	COG3956	TIGRFAM MazG family protein
AWQ23_04115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ23_04120	COG0678	peroxiredoxin activity
AWQ23_04125	COG3273	potassium ion transport
AWQ23_04125	COG0471	metal ion transport
AWQ23_04130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWQ23_04135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWQ23_04140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AWQ23_04145	COG4208	sulfate ABC transporter
AWQ23_04150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWQ23_04190	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ23_04190	COG0515	serine threonine protein kinase
AWQ23_04210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ23_04225	COG0105	UTP biosynthetic process
AWQ23_04240	COG2226	methyltransferase
AWQ23_04245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWQ23_04260	COG1132	(ABC) transporter
AWQ23_04270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWQ23_04275	COG1446	asparaginase
AWQ23_04285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ23_04320	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWQ23_04330	COG0456	acetyltransferase
AWQ23_04335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ23_04335	COG0784	Response regulator, receiver
AWQ23_04335	COG2198	Histidine kinase
AWQ23_04335	COG2205	protein histidine kinase activity
AWQ23_04340	COG2048	Heterodisulfide reductase, subunit B
AWQ23_04370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ23_04375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ23_04380	COG0793	Belongs to the peptidase S41A family
AWQ23_04395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWQ23_04405	COG2203	Gaf domain
AWQ23_04405	COG5001	Diguanylate cyclase
AWQ23_04405	COG4251	negative regulation of phosphorylation
AWQ23_04405	COG3706	GGDEF domain
AWQ23_04420	COG0745	RESPONSE REGULATOR receiver
AWQ23_04425	COG2203	Gaf domain
AWQ23_04430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ23_04435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ23_04450	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AWQ23_04455	COG0745	RESPONSE REGULATOR receiver
AWQ23_04460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ23_04465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ23_04470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ23_04470	COG1116	anion transmembrane transporter activity
AWQ23_04475	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ23_04485	COG2205	protein histidine kinase activity
AWQ23_04495	COG5002	protein histidine kinase activity
AWQ23_04495	COG2198	Histidine kinase
AWQ23_04495	COG0784	Response regulator, receiver
AWQ23_04500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AWQ23_04505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AWQ23_04510	COG3266	domain, Protein
AWQ23_04510	COG0515	serine threonine protein kinase
AWQ23_04520	COG0799	negative regulation of ribosome biogenesis
AWQ23_04525	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ23_04545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWQ23_04550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWQ23_04565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWQ23_04570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWQ23_04575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWQ23_04580	COG0540	Belongs to the ATCase OTCase family
AWQ23_04595	COG3100	YcgL domain-containing protein
AWQ23_04595	COG0561	phosphatase activity
AWQ23_04600	COG0438	transferase activity, transferring glycosyl groups
AWQ23_04605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWQ23_04615	COG0045	succinate-CoA ligase (ADP-forming) activity
AWQ23_04645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWQ23_04660	COG5002	protein histidine kinase activity
AWQ23_04670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_04675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWQ23_04685	COG1691	(AIR) carboxylase
AWQ23_04690	COG0745	RESPONSE REGULATOR receiver
AWQ23_04700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ23_04710	COG1136	(ABC) transporter
AWQ23_04720	COG2166	iron-sulfur cluster assembly
AWQ23_04730	COG0489	protein tyrosine kinase activity
AWQ23_04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ23_04760	COG4251	negative regulation of phosphorylation
AWQ23_04765	COG1104	cysteine desulfurase activity
AWQ23_04775	COG0713	ATP synthesis coupled electron transport
AWQ23_04780	COG0839	Belongs to the complex I subunit 6 family
AWQ23_04785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_04790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AWQ23_04795	COG1716	ATPase activity
AWQ23_04800	COG0363	glucosamine-6-phosphate deaminase activity
AWQ23_04815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ23_04845	COG0745	RESPONSE REGULATOR receiver
AWQ23_04850	COG1702	phosphate starvation-inducible protein PhoH
AWQ23_04860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ23_04870	COG2310	stress, protein
AWQ23_04880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWQ23_04890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWQ23_04910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ23_04920	COG0233	cytoplasmic translational termination
AWQ23_04925	COG0528	UMP kinase activity
AWQ23_04935	COG0539	negative regulation of cytoplasmic translation
AWQ23_04940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWQ23_04950	COG0564	pseudouridine synthase activity
AWQ23_04970	COG1404	Belongs to the peptidase S8 family
AWQ23_04975	COG0166	Belongs to the GPI family
AWQ23_05015	COG0386	Belongs to the glutathione peroxidase family
AWQ23_05030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ23_05040	COG0434	BtpA family
AWQ23_05050	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWQ23_05055	COG0745	RESPONSE REGULATOR receiver
AWQ23_05060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ23_05060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ23_05075	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AWQ23_05080	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ23_05085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ23_05100	COG0594	ribonuclease P activity
AWQ23_05110	COG0706	membrane insertase activity
AWQ23_05125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_05135	COG5002	protein histidine kinase activity
AWQ23_05135	COG0784	Response regulator, receiver
AWQ23_05135	COG2205	protein histidine kinase activity
AWQ23_05155	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ23_05165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ23_05170	COG0025	NhaP-type Na H and K H
AWQ23_05180	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ23_05185	COG0788	formyltetrahydrofolate deformylase activity
AWQ23_05190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWQ23_05225	COG1716	ATPase activity
AWQ23_05235	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ23_05255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWQ23_05260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ23_05265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWQ23_05270	COG0154	amidase activity
AWQ23_05275	COG0222	ribosome binding
AWQ23_05280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWQ23_05285	COG0081	regulation of translation
AWQ23_05290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWQ23_05295	COG0250	Participates in transcription elongation, termination and antitermination
AWQ23_05300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWQ23_05310	COG0335	large ribosomal subunit rRNA binding
AWQ23_05315	COG3659	wide pore channel activity
AWQ23_05325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWQ23_05330	COG0254	rRNA binding
AWQ23_05335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWQ23_05340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWQ23_05345	COG0101	tRNA pseudouridine synthase activity
AWQ23_05350	COG0203	ribosomal protein L17
AWQ23_05365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWQ23_05375	COG0563	adenylate kinase activity
AWQ23_05380	COG0201	protein transport
AWQ23_05385	COG0200	Binds to the 23S rRNA
AWQ23_05390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWQ23_05395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWQ23_05400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWQ23_05405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWQ23_05410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWQ23_05415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWQ23_05420	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWQ23_05430	COG0255	Belongs to the universal ribosomal protein uL29 family
AWQ23_05435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWQ23_05440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWQ23_05445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWQ23_05450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWQ23_05455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWQ23_05470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWQ23_05475	COG1185	polyribonucleotide nucleotidyltransferase activity
AWQ23_05495	COG0004	ammonium transporteR
AWQ23_05500	COG1012	belongs to the aldehyde dehydrogenase family
AWQ23_05555	COG3688	RNA-binding protein containing a PIN domain
AWQ23_05560	COG2112	serine threonine protein kinase
AWQ23_05570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ23_05580	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWQ23_05595	COG4399	Belongs to the UPF0754 family
AWQ23_05600	COG1333	cytochrome c biogenesis protein
AWQ23_05620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ23_05650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ23_05660	COG2226	methyltransferase
AWQ23_05685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWQ23_05695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ23_05700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ23_05705	COG0010	Belongs to the arginase family
AWQ23_05715	COG4251	negative regulation of phosphorylation
AWQ23_05720	COG0445	tRNA wobble uridine modification
AWQ23_05725	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWQ23_05750	COG1196	nuclear chromosome segregation
AWQ23_05755	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWQ23_05760	COG2226	methyltransferase
AWQ23_05775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWQ23_05790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWQ23_05810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWQ23_05815	COG0616	signal peptide processing
AWQ23_05825	COG0385	Bile acid
AWQ23_05830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWQ23_05850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWQ23_05855	COG0189	ligase activity
AWQ23_05870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWQ23_05910	COG0561	phosphatase activity
AWQ23_05915	COG1982	Orn Lys Arg decarboxylase major
AWQ23_05920	COG0109	protoheme IX farnesyltransferase activity
AWQ23_05925	COG1612	heme a metabolic process
AWQ23_05930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ23_05935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWQ23_05940	COG1845	cytochrome c oxidase, subunit III
AWQ23_05950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWQ23_05965	COG0629	single-stranded DNA binding
AWQ23_05970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ23_05975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ23_05980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWQ23_05995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWQ23_06000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_06005	COG0668	transmembrane transport
AWQ23_06025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ23_06105	COG0826	peptidase U32
AWQ23_06115	COG1587	Uroporphyrinogen-III synthase
AWQ23_06120	COG0740	serine-type endopeptidase activity
AWQ23_06125	COG0740	serine-type endopeptidase activity
AWQ23_06130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWQ23_06135	COG3118	belongs to the thioredoxin family
AWQ23_06145	COG0583	DNA-binding transcription factor activity
AWQ23_06155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWQ23_06165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ23_06170	COG0436	Aminotransferase
AWQ23_06185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ23_06205	COG1253	flavin adenine dinucleotide binding
AWQ23_06225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWQ23_06235	COG0525	valine-tRNA ligase activity
AWQ23_06245	COG0772	Belongs to the SEDS family
AWQ23_06275	COG0745	RESPONSE REGULATOR receiver
AWQ23_06280	COG0805	protein transport
AWQ23_06300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWQ23_06335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ23_06365	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AWQ23_06395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ23_06400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWQ23_06405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWQ23_06410	COG2264	protein methyltransferase activity
AWQ23_06425	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ23_06445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWQ23_06450	COG0395	ABC-type sugar transport system, permease component
AWQ23_06455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ23_06470	COG0653	protein targeting
AWQ23_06480	COG0784	Response regulator, receiver
AWQ23_06480	COG2205	protein histidine kinase activity
AWQ23_06480	COG5002	protein histidine kinase activity
AWQ23_06490	COG0592	DNA-directed DNA polymerase activity
AWQ23_06520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWQ23_06525	COG0632	four-way junction helicase activity
AWQ23_06530	COG1372	Participates in initiation and elongation during chromosome replication
AWQ23_06530	COG0305	Participates in initiation and elongation during chromosome replication
AWQ23_06530	COG1372	Participates in initiation and elongation during chromosome replication
AWQ23_06530	COG0305	Participates in initiation and elongation during chromosome replication
AWQ23_06540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWQ23_06545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWQ23_06550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWQ23_06560	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWQ23_06565	COG0024	Methionine aminopeptidase
AWQ23_06570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWQ23_06585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ23_06585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ23_06590	COG0156	8-amino-7-oxononanoate synthase activity
AWQ23_06605	COG0824	Thioesterase
AWQ23_06610	COG0347	Belongs to the P(II) protein family
AWQ23_06620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWQ23_06625	COG1366	Belongs to the anti-sigma-factor antagonist family
AWQ23_06635	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AWQ23_06640	COG0716	FMN binding
AWQ23_06650	COG0708	Exodeoxyribonuclease III
AWQ23_06655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWQ23_06675	COG0672	)-iron permease
AWQ23_06685	COG1494	fructose-1,6-bisphosphatase
AWQ23_06690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWQ23_06720	COG0745	RESPONSE REGULATOR receiver
AWQ23_06725	COG1372	Participates in initiation and elongation during chromosome replication
AWQ23_06725	COG0719	Fe-S assembly protein
AWQ23_06730	COG0717	Belongs to the dCTP deaminase family
AWQ23_06745	COG2223	nitrite transmembrane transporter activity
AWQ23_06750	COG0243	molybdopterin cofactor binding
AWQ23_06760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWQ23_06765	COG0848	biopolymer transport protein
AWQ23_06770	COG0811	peptide transport
AWQ23_06775	COG0831	urea catabolic process
AWQ23_06785	COG0426	domain, Protein
AWQ23_06785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ23_06805	COG0617	tRNA 3'-terminal CCA addition
AWQ23_06820	COG1192	Involved in chromosome partitioning
AWQ23_06865	COG0393	Putative heavy-metal-binding
AWQ23_06895	COG0187	DNA topoisomerase II activity
AWQ23_06895	COG1372	Participates in initiation and elongation during chromosome replication
AWQ23_06900	COG2046	Belongs to the sulfate adenylyltransferase family
AWQ23_06905	COG0358	DNA primase activity
AWQ23_06930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ23_06940	COG0191	fructose-bisphosphate aldolase activity
AWQ23_06945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWQ23_06950	COG2205	protein histidine kinase activity
AWQ23_06955	COG5001	Diguanylate cyclase
AWQ23_06960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ23_06985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWQ23_06990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWQ23_06990	COG0519	Catalyzes the synthesis of GMP from XMP
AWQ23_06995	COG5002	protein histidine kinase activity
AWQ23_07030	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWQ23_07035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ23_07040	COG0840	transmembrane signaling receptor activity
AWQ23_07050	COG0745	RESPONSE REGULATOR receiver
AWQ23_07065	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AWQ23_07085	COG1178	ABC-type Fe3 transport system permease component
AWQ23_07090	COG5002	protein histidine kinase activity
AWQ23_07090	COG2198	Histidine kinase
AWQ23_07090	COG0784	Response regulator, receiver
AWQ23_07100	COG5002	protein histidine kinase activity
AWQ23_07125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ23_07130	COG2255	four-way junction helicase activity
AWQ23_07150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ23_07180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ23_07185	COG0248	Ppx GppA phosphatase
AWQ23_07190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWQ23_07205	COG5002	protein histidine kinase activity
AWQ23_07210	COG0151	Belongs to the GarS family
AWQ23_07215	COG0392	lysyltransferase activity
AWQ23_07220	COG0587	DNA-directed DNA polymerase activity
AWQ23_07225	COG4636	protein conserved in cyanobacteria
AWQ23_07230	COG2133	pyrroloquinoline quinone binding
AWQ23_07235	COG0163	prenyltransferase activity
AWQ23_07245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWQ23_07250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AWQ23_07285	COG0504	CTP synthase activity
AWQ23_07295	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWQ23_07300	COG0463	Glycosyl transferase, family 2
AWQ23_07310	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AWQ23_07320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWQ23_07325	COG3536	Protein conserved in bacteria
AWQ23_07360	COG0681	Belongs to the peptidase S26 family
AWQ23_07370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ23_07380	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWQ23_07400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AWQ23_07400	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWQ23_07400	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWQ23_07400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AWQ23_07415	COG0438	transferase activity, transferring glycosyl groups
AWQ23_07425	COG1132	(ABC) transporter
AWQ23_07440	COG5002	protein histidine kinase activity
AWQ23_07445	COG0745	RESPONSE REGULATOR receiver
AWQ23_07460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ23_07475	COG3409	Peptidoglycan-binding domain 1 protein
AWQ23_07475	COG3429	Glucose-6-phosphate dehydrogenase subunit
AWQ23_07480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWQ23_07485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ23_07490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ23_07495	COG0586	Pfam SNARE associated Golgi protein
AWQ23_07505	COG2226	methyltransferase
AWQ23_07510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ23_07510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ23_07520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWQ23_07525	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ23_07540	COG2843	Capsule synthesis protein
AWQ23_07550	COG0667	Aldo Keto reductase
AWQ23_07560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ23_07645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ23_07660	COG0529	Catalyzes the synthesis of activated sulfate
AWQ23_07665	COG0617	tRNA 3'-terminal CCA addition
AWQ23_07675	COG0175	sulfate reduction
AWQ23_07680	COG0359	binds to the 23S rRNA
AWQ23_07685	COG2199	diguanylate cyclase activity
AWQ23_07690	COG0489	protein tyrosine kinase activity
AWQ23_07735	COG1216	Glycosyl transferase, family 2
AWQ23_07760	COG0438	transferase activity, transferring glycosyl groups
AWQ23_07765	COG2192	nodulation
AWQ23_07770	COG0438	transferase activity, transferring glycosyl groups
AWQ23_07780	COG0438	transferase activity, transferring glycosyl groups
AWQ23_07785	COG0463	Glycosyl transferase, family 2
AWQ23_07800	COG1598	PFAM Uncharacterised protein family UPF0150
AWQ23_07810	COG0110	maltose O-acetyltransferase activity
AWQ23_07815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWQ23_07825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ23_07835	COG1077	Cell shape determining protein MreB Mrl
AWQ23_07860	COG4636	protein conserved in cyanobacteria
AWQ23_07870	COG0297	glycogen (starch) synthase activity
AWQ23_07880	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWQ23_07885	COG0740	serine-type endopeptidase activity
AWQ23_07925	COG0557	exoribonuclease II activity
AWQ23_07935	COG0047	phosphoribosylformylglycinamidine synthase activity
AWQ23_07940	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ23_07945	COG0701	Predicted permease
AWQ23_07950	COG0745	RESPONSE REGULATOR receiver
AWQ23_07955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ23_07955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ23_07960	COG2267	carboxylic ester hydrolase activity
AWQ23_07985	COG0095	Lipoate-protein ligase
AWQ23_07990	COG2226	methyltransferase
AWQ23_08000	COG2084	Dehydrogenase
AWQ23_08020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWQ23_08025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWQ23_08030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ23_08035	COG0457	Tetratricopeptide repeat
AWQ23_08050	COG4783	chaperone-mediated protein folding
AWQ23_08065	COG1090	epimerase
AWQ23_08080	COG0628	permease
AWQ23_08090	COG0745	RESPONSE REGULATOR receiver
AWQ23_08095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ23_08125	COG0247	lactate metabolic process
AWQ23_08130	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWQ23_08135	COG0126	phosphoglycerate kinase activity
AWQ23_08140	COG0589	response to stress
AWQ23_08145	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ23_08155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AWQ23_08175	COG0454	-acetyltransferase
AWQ23_08200	COG2890	protein-(glutamine-N5) methyltransferase activity
AWQ23_08240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ23_08245	COG0768	penicillin binding
AWQ23_08250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWQ23_08255	COG0181	hydroxymethylbilane synthase activity
AWQ23_08275	COG3118	belongs to the thioredoxin family
AWQ23_08285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWQ23_08295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ23_08305	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWQ23_08310	COG2346	COG2346, Truncated hemoglobins
AWQ23_08315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWQ23_08320	COG1233	COG1233 Phytoene dehydrogenase and related
AWQ23_08325	COG2161	toxin-antitoxin pair type II binding
AWQ23_08330	COG4115	mRNA cleavage
AWQ23_08335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ23_08345	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ23_08350	COG0724	RNA recognition motif
AWQ23_08355	COG0174	glutamine synthetase
AWQ23_08365	COG0583	DNA-binding transcription factor activity
AWQ23_08390	COG2385	sporulation resulting in formation of a cellular spore
AWQ23_08390	COG2247	cell wall binding repeat
AWQ23_08400	COG0217	transcriptional regulatory protein
AWQ23_08405	COG2205	protein histidine kinase activity
AWQ23_08410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWQ23_08420	COG0739	heme binding
AWQ23_08420	COG0741	lytic transglycosylase activity
AWQ23_08420	COG1196	nuclear chromosome segregation
AWQ23_08425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ23_08430	COG1045	serine acetyltransferase
AWQ23_08440	COG1120	ATPase activity
AWQ23_08445	COG0735	belongs to the Fur family
AWQ23_08465	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ23_08470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWQ23_08475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ23_08480	COG0442	prolyl-tRNA aminoacylation
AWQ23_08485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ23_08490	COG0469	pyruvate kinase activity
AWQ23_08525	COG0515	serine threonine protein kinase
AWQ23_08535	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ23_08555	COG0517	IMP dehydrogenase activity
AWQ23_08555	COG1994	Peptidase M50
AWQ23_08565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWQ23_08575	COG4372	Transposase
AWQ23_08585	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWQ23_08590	COG0275	rRNA processing
AWQ23_08605	COG0116	Belongs to the methyltransferase superfamily
AWQ23_08610	COG0515	serine threonine protein kinase
AWQ23_08615	COG1049	propionate catabolic process, 2-methylcitrate cycle
AWQ23_08655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWQ23_08660	COG0314	molybdopterin synthase activity
AWQ23_08670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWQ23_08680	COG0495	leucyl-tRNA aminoacylation
AWQ23_08715	COG2310	stress, protein
AWQ23_08720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ23_08725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ23_08735	COG0328	RNA-DNA hybrid ribonuclease activity
AWQ23_08740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ23_08745	COG0704	Plays a role in the regulation of phosphate uptake
AWQ23_08750	COG0009	L-threonylcarbamoyladenylate synthase
AWQ23_08755	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AWQ23_08775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWQ23_08780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWQ23_08795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWQ23_08800	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AWQ23_08800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ23_08805	COG0842	Transport permease protein
AWQ23_08815	COG1131	(ABC) transporter
AWQ23_08820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ23_08840	COG0515	serine threonine protein kinase
AWQ23_08840	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ23_08845	COG0012	GTP binding
AWQ23_08855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWQ23_08870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ23_08875	COG1121	(ABC) transporter
AWQ23_08890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ23_08890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ23_08895	COG0484	heat shock protein binding
AWQ23_08900	COG3174	membrane
AWQ23_08910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWQ23_08915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AWQ23_08920	COG0426	domain, Protein
AWQ23_08920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ23_08925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWQ23_08935	COG0375	protein maturation
AWQ23_08940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ23_08950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ23_08955	COG1116	anion transmembrane transporter activity
AWQ23_08960	COG0010	Belongs to the arginase family
AWQ23_08970	COG0113	porphobilinogen synthase activity
AWQ23_09000	COG0170	dolichyl monophosphate biosynthetic process
AWQ23_09020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWQ23_09025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ23_09025	COG0512	Glutamine amidotransferase of anthranilate synthase
AWQ23_09030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWQ23_09035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWQ23_09045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ23_09085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWQ23_09090	COG2226	methyltransferase
AWQ23_09095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ23_09095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWQ23_09100	COG1489	DNA binding
AWQ23_09140	COG2814	Major facilitator Superfamily
AWQ23_09150	COG0515	serine threonine protein kinase
AWQ23_09150	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ23_09155	COG4451	ribulose bisphosphate carboxylase, small
AWQ23_09165	COG1850	ribulose-bisphosphate carboxylase activity
AWQ23_09175	COG4451	ribulose bisphosphate carboxylase, small
AWQ23_09175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWQ23_09180	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AWQ23_09185	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ23_09190	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ23_09195	COG0659	secondary active sulfate transmembrane transporter activity
AWQ23_09200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ23_09215	COG1166	arginine decarboxylase activity
AWQ23_09225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ23_09230	COG0719	Fe-S assembly protein
AWQ23_09235	COG0396	ATPase activity
AWQ23_09240	COG0719	Fe-S assembly protein
AWQ23_09265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ23_09290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWQ23_09300	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWQ23_09305	COG2022	thiamine diphosphate biosynthetic process
AWQ23_09305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ23_09315	COG0408	coproporphyrinogen oxidase activity
AWQ23_09320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWQ23_09325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AWQ23_09335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ23_09340	COG0861	Integral membrane protein TerC family
AWQ23_09350	COG2045	Belongs to the ComB family
AWQ23_09365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWQ23_09390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ23_09395	COG0793	Belongs to the peptidase S41A family
AWQ23_09400	COG2052	Domain of unknown function (DUF370)
AWQ23_09405	COG0194	GDP metabolic process
AWQ23_09410	COG0740	serine-type endopeptidase activity
AWQ23_09420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWQ23_09430	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AWQ23_09450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ23_09455	COG0697	spore germination
AWQ23_09475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ23_09485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWQ23_09490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWQ23_09495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWQ23_09510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWQ23_09515	COG2385	sporulation resulting in formation of a cellular spore
AWQ23_09525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWQ23_09540	COG1716	ATPase activity
AWQ23_09540	COG0842	Transport permease protein
AWQ23_09540	COG1131	(ABC) transporter
AWQ23_09550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWQ23_09560	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ23_09565	COG3932	Exopolysaccharide synthesis, ExoD
AWQ23_09575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWQ23_09580	COG0859	PFAM glycosyl transferase family 9
AWQ23_09585	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWQ23_09605	COG0723	plastoquinol--plastocyanin reductase activity
AWQ23_09610	COG3258	Cytochrome c
AWQ23_09615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ23_09630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ23_09640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWQ23_09645	COG1799	cell septum assembly
AWQ23_09650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWQ23_09655	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AWQ23_09660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWQ23_09670	COG0037	tRNA processing
AWQ23_09675	COG1191	sigma factor activity
AWQ23_09680	COG0484	heat shock protein binding
AWQ23_09720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ23_09720	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ23_09725	COG1562	ergosterol biosynthetic process
AWQ23_09735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ23_09755	COG0023	Translation Initiation Factor
AWQ23_09780	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AWQ23_09785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ23_09805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ23_09810	COG5002	protein histidine kinase activity
AWQ23_09825	COG2197	response regulator
AWQ23_09830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWQ23_09835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWQ23_09840	COG0052	Belongs to the universal ribosomal protein uS2 family
AWQ23_09845	COG2885	chlorophyll binding
AWQ23_09850	COG2885	chlorophyll binding
AWQ23_09860	COG0628	permease
AWQ23_09865	COG0776	regulation of translation
AWQ23_09875	COG0390	transport system, permease component
AWQ23_09900	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_09910	COG2244	polysaccharide biosynthetic process
AWQ23_09920	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ23_09930	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ23_09950	COG1666	GTP binding
AWQ23_09955	COG1575	Belongs to the MenA family. Type 1 subfamily
AWQ23_09960	COG0131	Imidazoleglycerol-phosphate dehydratase
AWQ23_09980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ23_09985	COG5398	heme oxygenase
AWQ23_09990	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ23_09995	COG1733	regulation of RNA biosynthetic process
AWQ23_10000	COG0726	polysaccharide deacetylase
AWQ23_10005	COG0410	ABC transporter
AWQ23_10010	COG0411	ABC transporter
AWQ23_10015	COG0288	reversible hydration of carbon dioxide
AWQ23_10030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_10035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ23_10040	COG1420	regulation of RNA biosynthetic process
AWQ23_10045	COG1971	Probably functions as a manganese efflux pump
AWQ23_10065	COG0237	dephospho-CoA kinase activity
AWQ23_10065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ23_10070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ23_10085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ23_10090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ23_10100	COG2363	Small membrane protein
AWQ23_10110	COG0312	modulator of DNA gyrase
AWQ23_10115	COG0747	negative chemotaxis
AWQ23_10130	COG0366	Alpha amylase catalytic
AWQ23_10135	COG3769	mannosylglycerate metabolic process
AWQ23_10190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWQ23_10190	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AWQ23_10200	COG0395	ABC-type sugar transport system, permease component
AWQ23_10205	COG1175	transmembrane transport
AWQ23_10210	COG1653	transport
AWQ23_10215	COG3842	ATPase activity
AWQ23_10225	COG1027	Aspartate ammonia-lyase
AWQ23_10235	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ23_10240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ23_10245	COG0085	RNA polymerase activity
AWQ23_10250	COG0084	hydrolase, TatD family'
AWQ23_10255	COG0268	Binds directly to 16S ribosomal RNA
AWQ23_10305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ23_10315	COG0051	transcription antitermination factor activity, RNA binding
AWQ23_10320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWQ23_10325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ23_10330	COG0049	tRNA binding
AWQ23_10340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWQ23_10345	COG0316	Belongs to the HesB IscA family
AWQ23_10355	COG0590	tRNA wobble adenosine to inosine editing
AWQ23_10360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ23_10365	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AWQ23_10370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWQ23_10375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ23_10385	COG1597	lipid kinase activity
AWQ23_10395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ23_10415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ23_10435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ23_10460	COG4149	molybdate abc transporter
AWQ23_10470	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWQ23_10485	COG0039	L-malate dehydrogenase activity
AWQ23_10510	COG0418	dihydroorotase activity
AWQ23_10525	COG5002	protein histidine kinase activity
AWQ23_10535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWQ23_10540	COG0210	DNA helicase
AWQ23_10545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ23_10550	COG1131	(ABC) transporter
AWQ23_10555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ23_10570	COG1595	DNA-templated transcription, initiation
AWQ23_10590	COG0745	RESPONSE REGULATOR receiver
AWQ23_10605	COG1215	transferase activity, transferring glycosyl groups
AWQ23_10615	COG1252	NADH dehydrogenase
AWQ23_10625	COG0829	nickel cation binding
AWQ23_10645	COG0439	Biotin carboxylase
AWQ23_10665	COG0460	homoserine dehydrogenase
AWQ23_10670	COG1002	Type II restriction enzyme, methylase subunits
AWQ23_10690	COG4636	protein conserved in cyanobacteria
AWQ23_10740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWQ23_10750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWQ23_10755	COG0589	response to stress
AWQ23_10775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ23_10790	COG4636	protein conserved in cyanobacteria
AWQ23_10800	COG0443	Heat shock 70 kDa protein
AWQ23_10805	COG0484	heat shock protein binding
AWQ23_10810	COG0564	pseudouridine synthase activity
AWQ23_10815	COG0668	transmembrane transport
AWQ23_10835	COG5001	Diguanylate cyclase
AWQ23_10835	COG3300	MHYT domain
AWQ23_10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ23_10895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWQ23_10900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWQ23_10920	COG0463	Glycosyl transferase, family 2
AWQ23_10925	COG0003	Pfam Anion-transporting ATPase
AWQ23_10940	COG0436	Aminotransferase
AWQ23_10945	COG1132	(ABC) transporter
AWQ23_10955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ23_10970	COG0772	Belongs to the SEDS family
AWQ23_10975	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWQ23_11020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWQ23_11030	COG0004	ammonium transporteR
AWQ23_11045	COG0237	dephospho-CoA kinase activity
AWQ23_11050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ23_11055	COG1413	lyase activity
AWQ23_11060	COG1413	lyase activity
AWQ23_11070	COG0824	Thioesterase
AWQ23_11080	COG0537	adenosine 5'-monophosphoramidase activity
AWQ23_11090	COG1131	(ABC) transporter
AWQ23_11120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ23_11125	COG1131	(ABC) transporter
AWQ23_11140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWQ23_11170	COG1192	Involved in chromosome partitioning
AWQ23_11210	COG0193	aminoacyl-tRNA hydrolase activity
AWQ23_11235	COG0454	-acetyltransferase
AWQ23_11245	COG0556	nucleotide-excision repair
AWQ23_11250	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ23_11295	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AWQ23_11300	COG0569	domain protein
AWQ23_11305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWQ23_11320	COG4999	Histidine kinase
AWQ23_11320	COG3437	response regulator, receiver
AWQ23_11320	COG2205	protein histidine kinase activity
AWQ23_11320	COG3850	Histidine kinase
AWQ23_11340	COG0124	histidyl-tRNA synthetase
AWQ23_11350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWQ23_11365	COG2267	carboxylic ester hydrolase activity
AWQ23_11370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ23_11380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWQ23_11385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWQ23_11390	COG0573	inorganic phosphate transmembrane transporter activity
AWQ23_11395	COG0581	inorganic phosphate transmembrane transporter activity
AWQ23_11405	COG0802	atpase or kinase
AWQ23_11420	COG0315	cyclic pyranopterin monophosphate synthase activity
AWQ23_11430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ23_11435	COG3152	Membrane
AWQ23_11445	COG3046	protein related to deoxyribodipyrimidine photolyase
AWQ23_11455	COG0768	penicillin binding
AWQ23_11465	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWQ23_11470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ23_11490	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWQ23_11500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWQ23_11505	COG1252	NADH dehydrogenase
AWQ23_11515	COG0484	heat shock protein binding
AWQ23_11540	COG2217	Heavy metal translocating P-type atpase
AWQ23_11545	COG2132	Multicopper oxidase
AWQ23_11555	COG1836	PFAM Integral membrane protein DUF92
AWQ23_11570	COG0673	inositol 2-dehydrogenase activity
AWQ23_11580	COG0633	Ferredoxin
AWQ23_11585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_11595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWQ23_11600	COG0830	nickel cation binding
AWQ23_11615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ23_11630	COG0792	nuclease activity
AWQ23_11645	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWQ23_11660	COG0024	Methionine aminopeptidase
AWQ23_11685	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AWQ23_11690	COG0242	peptide deformylase activity
AWQ23_11715	COG0542	response to heat
AWQ23_11720	COG0473	3-isopropylmalate dehydrogenase activity
AWQ23_11730	COG2081	HI0933 family
AWQ23_11740	COG1187	pseudouridine synthase activity
AWQ23_11750	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWQ23_11760	COG2226	methyltransferase
AWQ23_11770	COG0539	negative regulation of cytoplasmic translation
AWQ23_11775	COG2203	Gaf domain
AWQ23_11775	COG5001	Diguanylate cyclase
AWQ23_11775	COG4251	negative regulation of phosphorylation
AWQ23_11775	COG3706	GGDEF domain
AWQ23_11780	COG5002	protein histidine kinase activity
AWQ23_11780	COG2205	protein histidine kinase activity
AWQ23_11780	COG0784	Response regulator, receiver
AWQ23_11785	COG0500	methyltransferase
AWQ23_11790	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ23_11795	COG3118	belongs to the thioredoxin family
AWQ23_11805	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AWQ23_11810	COG0659	secondary active sulfate transmembrane transporter activity
AWQ23_11815	COG0475	glutathione-regulated potassium exporter activity
AWQ23_11820	COG1006	Multisubunit Na H antiporter MnhC subunit
AWQ23_11830	COG0651	ATP synthesis coupled electron transport
AWQ23_11865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ23_11870	COG1051	belongs to the nudix hydrolase family
AWQ23_11870	COG1056	cytidyltransferase-related domain
AWQ23_11875	COG0587	DNA-directed DNA polymerase activity
AWQ23_11885	COG1187	pseudouridine synthase activity
AWQ23_11910	COG2010	Cytochrome c
AWQ23_11920	COG0069	glutamate synthase activity
AWQ23_11920	COG0067	glutamate synthase
AWQ23_11920	COG0070	glutamate synthase
AWQ23_11925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWQ23_11940	COG1234	tRNA 3'-trailer cleavage
AWQ23_11945	COG0196	riboflavin kinase activity
AWQ23_11950	COG0714	Associated with various cellular activities
AWQ23_11965	COG1473	amidohydrolase
AWQ23_11975	COG0077	Prephenate dehydratase
AWQ23_11975	COG1605	Chorismate mutase
AWQ23_12000	COG1480	7TM receptor with intracellular HD hydrolase
AWQ23_12020	COG0435	Glutathione S-transferase
AWQ23_12035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWQ23_12050	COG0443	Heat shock 70 kDa protein
AWQ23_12065	COG0481	GTPase activity
AWQ23_12070	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AWQ23_12075	COG0589	response to stress
AWQ23_12080	COG0659	secondary active sulfate transmembrane transporter activity
AWQ23_12085	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWQ23_12115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ23_12130	COG0438	transferase activity, transferring glycosyl groups
AWQ23_12145	COG0832	Belongs to the urease beta subunit family
AWQ23_12150	COG1940	carbohydrate kinase activity
AWQ23_12165	COG1309	transcriptional regulator
AWQ23_12170	COG0670	Belongs to the BI1 family
AWQ23_12175	COG0825	malonyl-CoA metabolic process
AWQ23_12180	COG0302	gtp cyclohydrolase
AWQ23_12185	COG1902	pentaerythritol trinitrate reductase activity
AWQ23_12200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ23_12235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWQ23_12240	COG0751	glycine-tRNA ligase activity
AWQ23_12245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWQ23_12250	COG0459	protein refolding
AWQ23_12260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWQ23_12265	COG5001	Diguanylate cyclase
AWQ23_12270	COG1970	mechanosensitive ion channel activity
AWQ23_12280	COG1331	Highly conserved protein containing a thioredoxin domain
AWQ23_12295	COG0646	methionine synthase
AWQ23_12295	COG1410	methionine synthase
AWQ23_12305	COG0017	Asparaginyl-tRNA synthetase
AWQ23_12310	COG0431	NADPH-dependent FMN reductase
AWQ23_12325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWQ23_12340	COG0438	transferase activity, transferring glycosyl groups
AWQ23_12350	COG0644	oxidoreductase
AWQ23_12365	COG0575	Belongs to the CDS family
AWQ23_12405	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWQ23_12410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWQ23_12435	COG0612	Peptidase, M16
AWQ23_12445	COG0432	Pfam Uncharacterised protein family UPF0047
AWQ23_12460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ23_12465	COG1121	(ABC) transporter
AWQ23_12480	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ23_12490	COG0505	Belongs to the CarA family
AWQ23_12495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ23_12495	COG0758	DNA mediated transformation
AWQ23_12500	COG1840	ABC-type Fe3 transport system, periplasmic component
AWQ23_12505	COG5398	heme oxygenase
AWQ23_12515	COG2268	Band 7 protein
AWQ23_12530	COG0484	heat shock protein binding
AWQ23_12535	COG1690	Belongs to the RtcB family
AWQ23_12540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWQ23_12545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWQ23_12555	COG0300	oxidoreductase activity
AWQ23_12555	COG3000	fatty acid hydroxylase
AWQ23_12575	COG3411	Ferredoxin
AWQ23_12580	COG2197	response regulator
AWQ23_12590	COG1546	Belongs to the CinA family
AWQ23_12590	COG1058	Belongs to the CinA family
AWQ23_12595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWQ23_12645	COG0745	RESPONSE REGULATOR receiver
AWQ23_12655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ23_12665	COG0616	signal peptide processing
AWQ23_12670	COG0697	spore germination
AWQ23_12680	COG0649	NAD binding
AWQ23_12685	COG0571	ribonuclease III activity
AWQ23_12690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ23_12700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ23_12705	COG1754	DNA topoisomerase type I activity
AWQ23_12705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWQ23_12710	COG1007	ATP synthesis coupled electron transport
AWQ23_12720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWQ23_12725	COG0601	transmembrane transport
AWQ23_12760	COG2211	Major facilitator Superfamily
AWQ23_12765	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ23_12770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWQ23_12775	COG0406	alpha-ribazole phosphatase activity
AWQ23_12780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWQ23_12795	COG0640	Transcriptional regulator
AWQ23_12800	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AWQ23_12820	COG1053	succinate dehydrogenase
AWQ23_12830	COG3854	ATPases associated with a variety of cellular activities
AWQ23_12835	COG2373	Large extracellular alpha-helical protein
AWQ23_12850	COG5002	protein histidine kinase activity
AWQ23_12860	COG0612	Peptidase, M16
AWQ23_12900	COG3300	MHYT domain
AWQ23_12900	COG5001	Diguanylate cyclase
AWQ23_12905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ23_12910	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ23_12910	COG3347	Dehydrogenase
AWQ23_12925	COG0484	heat shock protein binding
AWQ23_12955	COG2203	Gaf domain
AWQ23_12955	COG0840	transmembrane signaling receptor activity
AWQ23_12970	COG0784	Response regulator, receiver
AWQ23_12975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ23_12980	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWQ23_12985	COG3693	PFAM glycoside hydrolase, family 10
AWQ23_13010	COG2217	Heavy metal translocating P-type atpase
AWQ23_13020	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ23_13025	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ23_13030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ23_13070	COG2062	phosphohistidine phosphatase, SixA
AWQ23_13075	COG0372	Belongs to the citrate synthase family
AWQ23_13085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ23_13095	COG0419	ATPase involved in DNA repair
AWQ23_13125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ23_13130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWQ23_13150	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AWQ23_13170	COG4948	Mandelate Racemase Muconate Lactonizing
AWQ23_13180	COG2205	protein histidine kinase activity
AWQ23_13180	COG3850	Histidine kinase
AWQ23_13180	COG4999	Histidine kinase
AWQ23_13180	COG3437	response regulator, receiver
AWQ23_13195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ23_13225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWQ23_13230	COG2200	EAL domain
AWQ23_13235	COG0523	cobalamin synthesis protein
AWQ23_13245	COG3659	wide pore channel activity
AWQ23_13250	COG3128	pkhd-type hydroxylase
AWQ23_13275	COG2193	ferroxidase activity
AWQ23_13280	COG0572	uridine kinase
AWQ23_13290	COG0415	Belongs to the DNA photolyase family
AWQ23_13300	COG0596	Alpha beta hydrolase
AWQ23_13335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ23_13370	COG4249	Peptidase C14 caspase catalytic subunit p20
AWQ23_13370	COG2319	Wd-40 repeat
AWQ23_13400	COG0589	response to stress
AWQ23_13405	COG1672	PFAM Archaeal ATPase
AWQ23_13410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWQ23_13420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ23_13425	COG0330	HflC and HflK could
AWQ23_13450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWQ23_13455	COG2267	carboxylic ester hydrolase activity
AWQ23_13460	COG0440	acetolactate synthase activity
AWQ23_13470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ23_13485	COG0482	sulfurtransferase activity
AWQ23_13490	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AWQ23_13505	COG0237	dephospho-CoA kinase activity
AWQ23_13545	COG1741	Belongs to the pirin family
AWQ23_13565	COG1127	ABC transporter
AWQ23_13580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWQ23_13585	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AWQ23_13590	COG1122	ATPase activity
AWQ23_13620	COG0515	serine threonine protein kinase
AWQ23_13620	COG3266	domain, Protein
AWQ23_13635	COG0668	transmembrane transport
AWQ23_13640	COG2226	methyltransferase
AWQ23_13655	COG3012	SEC-C Motif Domain Protein
AWQ23_13665	COG0709	Synthesizes selenophosphate from selenide and ATP
AWQ23_13670	COG0683	leucine binding
AWQ23_13680	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_13685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_13690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ23_13695	COG2319	Wd-40 repeat
AWQ23_13710	COG0004	ammonium transporteR
AWQ23_13715	COG3239	Fatty acid desaturase
AWQ23_13725	COG2119	membrane
AWQ23_13740	COG1473	amidohydrolase
AWQ23_13750	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AWQ23_13755	COG5001	Diguanylate cyclase
AWQ23_13755	COG1716	ATPase activity
AWQ23_13760	COG2304	oxidoreductase activity
AWQ23_13765	COG2501	S4 domain
AWQ23_13770	COG0412	Dienelactone hydrolase
AWQ23_13785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWQ23_13790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AWQ23_13800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWQ23_13810	COG1012	belongs to the aldehyde dehydrogenase family
AWQ23_13835	COG0686	Belongs to the AlaDH PNT family
AWQ23_13840	COG0582	viral genome integration into host DNA
AWQ23_13855	COG0625	glutathione transferase activity
AWQ23_13865	COG0343	queuine tRNA-ribosyltransferase activity
AWQ23_13875	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AWQ23_13910	COG1132	(ABC) transporter
AWQ23_13915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWQ23_13920	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ23_13930	COG0552	protein localization to endoplasmic reticulum
AWQ23_13935	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ23_13940	COG0415	Belongs to the DNA photolyase family
AWQ23_13965	COG2442	InterPro IPR007367
AWQ23_13975	COG4968	Prepilin-type N-terminal cleavage methylation domain
AWQ23_13995	COG0137	argininosuccinate synthase activity
AWQ23_14000	COG1234	tRNA 3'-trailer cleavage
AWQ23_14020	COG0312	modulator of DNA gyrase
AWQ23_14025	COG2154	pterin-4-alpha-carbinolamine dehydratase
AWQ23_14030	COG3659	wide pore channel activity
AWQ23_14035	COG2084	Dehydrogenase
AWQ23_14040	COG2203	Gaf domain
AWQ23_14040	COG3706	GGDEF domain
AWQ23_14040	COG4251	negative regulation of phosphorylation
AWQ23_14040	COG5001	Diguanylate cyclase
AWQ23_14045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ23_14060	COG1543	Belongs to the glycosyl hydrolase 57 family
AWQ23_14075	COG1950	PFAM Membrane protein of
AWQ23_14085	COG3339	Conserved Protein
AWQ23_14095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWQ23_14100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWQ23_14115	COG4956	integral membrane protein (PIN domain superfamily)
AWQ23_14120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ23_14125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ23_14140	COG4251	negative regulation of phosphorylation
AWQ23_14175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWQ23_14190	COG2211	Major facilitator Superfamily
AWQ23_14240	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AWQ23_14245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWQ23_14250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWQ23_14255	COG0135	phosphoribosylanthranilate isomerase activity
AWQ23_14260	COG0746	molybdenum cofactor guanylyltransferase activity
AWQ23_14270	COG3954	Phosphoribulokinase
AWQ23_14275	COG0277	FAD linked oxidase domain protein
AWQ23_14285	COG1487	ribonuclease activity
AWQ23_14310	COG2203	Gaf domain
AWQ23_14310	COG5001	Diguanylate cyclase
AWQ23_14310	COG3706	GGDEF domain
AWQ23_14310	COG4251	negative regulation of phosphorylation
AWQ23_14315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWQ23_14325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ23_14330	COG0730	response to heat
AWQ23_14345	COG2304	oxidoreductase activity
AWQ23_14350	COG0215	cysteine-tRNA ligase activity
AWQ23_14375	COG1061	Type III restriction enzyme res subunit
AWQ23_14415	COG1192	Involved in chromosome partitioning
AWQ23_14440	COG1061	Type III restriction enzyme res subunit
AWQ23_14475	COG1192	Involved in chromosome partitioning
AWQ23_14500	COG0343	queuine tRNA-ribosyltransferase activity
AWQ23_14505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ23_14535	COG0210	DNA helicase
AWQ23_14720	COG2217	Heavy metal translocating P-type atpase
AWQ23_14740	COG2132	Multicopper oxidase
AWQ23_14760	COG5002	protein histidine kinase activity
AWQ23_14975	COG2205	protein histidine kinase activity
AWQ23_14980	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AWQ23_14985	COG0737	Belongs to the 5'-nucleotidase family
AWQ23_15030	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWQ23_15035	COG0723	plastoquinol--plastocyanin reductase activity
AWQ23_15045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ23_15050	COG1120	ATPase activity
AWQ23_15065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ23_15090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ23_15095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ23_15110	COG2124	cytochrome p450
AWQ23_15225	COG0113	porphobilinogen synthase activity
AWQ23_15230	COG0302	gtp cyclohydrolase
AWQ23_15240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWQ23_15260	COG0405	Gamma-glutamyltransferase
AWQ23_15265	COG0848	biopolymer transport protein
AWQ23_15270	COG0811	peptide transport
AWQ23_15280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ23_15285	COG2304	oxidoreductase activity
AWQ23_15295	COG0515	serine threonine protein kinase
AWQ23_15340	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWQ23_15350	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ23_15355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWQ23_15385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ23_15395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ23_15400	COG3447	MASE1 domain protein
AWQ23_15400	COG5001	Diguanylate cyclase
AWQ23_15400	COG5002	protein histidine kinase activity
AWQ23_15405	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AWQ23_15410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AWQ23_15425	COG0745	RESPONSE REGULATOR receiver
AWQ23_15430	COG5002	protein histidine kinase activity
AWQ23_15430	COG3850	Histidine kinase
AWQ23_15450	COG0398	Pfam SNARE associated Golgi protein
AWQ23_15455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWQ23_15500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ23_15505	COG3932	Exopolysaccharide synthesis, ExoD
AWQ23_15510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ23_15510	COG1116	anion transmembrane transporter activity
AWQ23_15515	COG1116	anion transmembrane transporter activity
AWQ23_15515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ23_15520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ23_15535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWQ23_15550	COG3239	Fatty acid desaturase
AWQ23_15555	COG2226	methyltransferase
AWQ23_15575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily