locus-tag	class	description
AWQ24_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWQ24_00030	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AWQ24_00035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWQ24_00040	COG0662	Cupin 2, conserved barrel domain protein
AWQ24_00040	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AWQ24_00050	COG1830	Aldolase
AWQ24_00055	COG4636	protein conserved in cyanobacteria
AWQ24_00090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_00095	COG0742	ribosomal rna small subunit methyltransferase
AWQ24_00115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWQ24_00120	COG0351	phosphomethylpyrimidine kinase
AWQ24_00125	COG1160	GTP binding
AWQ24_00130	COG0572	uridine kinase
AWQ24_00135	COG1280	lysine exporter protein (LysE YggA)
AWQ24_00145	COG0783	Belongs to the Dps family
AWQ24_00155	COG1253	flavin adenine dinucleotide binding
AWQ24_00165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWQ24_00175	COG0180	Tryptophanyl-tRNA synthetase
AWQ24_00185	COG0384	phenazine biosynthesis protein PhzF
AWQ24_00190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_00225	COG0784	Response regulator, receiver
AWQ24_00240	COG2203	Gaf domain
AWQ24_00240	COG0840	transmembrane signaling receptor activity
AWQ24_00260	COG0511	ligase activity, forming carbon-carbon bonds
AWQ24_00265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWQ24_00285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWQ24_00295	COG0494	nUDIX hydrolase
AWQ24_00300	COG0571	ribonuclease III activity
AWQ24_00315	COG0737	Belongs to the 5'-nucleotidase family
AWQ24_00325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AWQ24_00330	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ24_00345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWQ24_00440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWQ24_00445	COG0148	phosphopyruvate hydratase activity
AWQ24_00450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWQ24_00455	COG1472	Belongs to the glycosyl hydrolase 3 family
AWQ24_00470	COG3937	granule-associated protein
AWQ24_00480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ24_00490	COG3409	Peptidoglycan-binding domain 1 protein
AWQ24_00490	COG3773	Cell wall hydrolase
AWQ24_00495	COG0612	Peptidase, M16
AWQ24_00500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWQ24_00500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWQ24_00535	COG0083	homoserine kinase activity
AWQ24_00555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ24_00560	COG0456	acetyltransferase
AWQ24_00570	COG0019	diaminopimelate decarboxylase activity
AWQ24_00575	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWQ24_00580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWQ24_00600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWQ24_00610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWQ24_00620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWQ24_00625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ24_00630	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ24_00635	COG2010	Cytochrome c
AWQ24_00655	COG0656	L-ascorbic acid biosynthetic process
AWQ24_00660	COG0386	Belongs to the glutathione peroxidase family
AWQ24_00670	COG0629	single-stranded DNA binding
AWQ24_00675	COG4172	Belongs to the ABC transporter superfamily
AWQ24_00680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWQ24_00685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ24_00690	COG0494	nUDIX hydrolase
AWQ24_00695	COG1160	GTP binding
AWQ24_00700	COG3268	Saccharopine dehydrogenase
AWQ24_00705	COG2116	formate transmembrane transporter activity
AWQ24_00710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ24_00720	COG1959	2 iron, 2 sulfur cluster binding
AWQ24_00735	COG0789	Transcriptional regulator
AWQ24_00745	COG1175	transmembrane transport
AWQ24_00750	COG0728	peptidoglycan biosynthetic process
AWQ24_00760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWQ24_00770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AWQ24_00785	COG0542	response to heat
AWQ24_00800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ24_00840	COG0459	protein refolding
AWQ24_00845	COG0784	Response regulator, receiver
AWQ24_00845	COG2205	protein histidine kinase activity
AWQ24_00845	COG5002	protein histidine kinase activity
AWQ24_00860	COG0737	Belongs to the 5'-nucleotidase family
AWQ24_00865	COG0668	transmembrane transport
AWQ24_00885	COG0756	dUTP diphosphatase activity
AWQ24_00905	COG3239	Fatty acid desaturase
AWQ24_00920	COG0205	6-phosphofructokinase activity
AWQ24_00935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ24_00945	COG1131	(ABC) transporter
AWQ24_00950	COG2010	Cytochrome c
AWQ24_00965	COG2124	cytochrome p450
AWQ24_00970	COG0583	DNA-binding transcription factor activity
AWQ24_00975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ24_00980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_00990	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ24_00995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWQ24_00995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWQ24_01000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWQ24_01005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWQ24_01025	COG1404	Belongs to the peptidase S8 family
AWQ24_01025	COG4935	Belongs to the peptidase S8 family
AWQ24_01035	COG0457	Tetratricopeptide repeat
AWQ24_01035	COG0463	Glycosyl transferase, family 2
AWQ24_01050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ24_01075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWQ24_01080	COG4636	protein conserved in cyanobacteria
AWQ24_01085	COG0804	urea catabolic process
AWQ24_01110	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AWQ24_01120	COG3259	Nickel-dependent hydrogenase
AWQ24_01135	COG0375	protein maturation
AWQ24_01140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ24_01145	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AWQ24_01150	COG0298	carbon dioxide binding
AWQ24_01170	COG1490	D-aminoacyl-tRNA deacylase activity
AWQ24_01175	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ24_01190	COG0793	Belongs to the peptidase S41A family
AWQ24_01200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ24_01205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ24_01210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ24_01215	COG0745	RESPONSE REGULATOR receiver
AWQ24_01225	COG2003	Belongs to the UPF0758 family
AWQ24_01230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWQ24_01235	COG0312	modulator of DNA gyrase
AWQ24_01255	COG0316	Belongs to the HesB IscA family
AWQ24_01260	COG0569	domain protein
AWQ24_01265	COG1773	rubredoxin
AWQ24_01270	COG4447	cellulose binding
AWQ24_01290	COG3977	Valine--pyruvate aminotransferase
AWQ24_01300	COG0322	excinuclease ABC activity
AWQ24_01315	COG1131	(ABC) transporter
AWQ24_01325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWQ24_01340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ24_01350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWQ24_01360	COG0574	Belongs to the PEP-utilizing enzyme family
AWQ24_01360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWQ24_01390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWQ24_01410	COG1968	undecaprenyl-diphosphatase activity
AWQ24_01420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWQ24_01430	COG0516	GMP reductase activity
AWQ24_01450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ24_01455	COG1834	amidinotransferase
AWQ24_01460	COG0724	RNA recognition motif
AWQ24_01465	COG2239	Acts as a magnesium transporter
AWQ24_01495	COG0352	thiamine-phosphate diphosphorylase activity
AWQ24_01500	COG0602	queuosine metabolic process
AWQ24_01505	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWQ24_01510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ24_01515	COG0589	response to stress
AWQ24_01515	COG0475	glutathione-regulated potassium exporter activity
AWQ24_01525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWQ24_01535	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AWQ24_01540	COG4251	negative regulation of phosphorylation
AWQ24_01550	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ24_01560	COG0436	Aminotransferase
AWQ24_01565	COG3118	belongs to the thioredoxin family
AWQ24_01570	COG1842	Phage shock protein A
AWQ24_01575	COG4251	negative regulation of phosphorylation
AWQ24_01580	COG0133	tryptophan synthase activity
AWQ24_01605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWQ24_01610	COG0783	Belongs to the Dps family
AWQ24_01635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWQ24_01645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWQ24_01655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWQ24_01670	COG0673	inositol 2-dehydrogenase activity
AWQ24_01680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWQ24_01685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWQ24_01690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWQ24_01700	COG0450	alkyl hydroperoxide reductase
AWQ24_01705	COG1555	photosystem II stabilization
AWQ24_01715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWQ24_01720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWQ24_01725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWQ24_01730	COG1032	radical SAM domain protein
AWQ24_01740	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AWQ24_01745	COG1640	4-alpha-glucanotransferase
AWQ24_01755	COG1192	Involved in chromosome partitioning
AWQ24_01775	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ24_01780	COG0346	lactoylglutathione lyase activity
AWQ24_01790	COG4953	penicillin-binding protein 1C
AWQ24_01800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ24_01810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWQ24_01810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWQ24_01815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ24_01820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWQ24_01830	COG0517	IMP dehydrogenase activity
AWQ24_01830	COG0516	GMP reductase activity
AWQ24_01840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_01855	COG0509	glycine decarboxylation via glycine cleavage system
AWQ24_01860	COG0006	proline dipeptidase activity
AWQ24_01865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWQ24_01870	COG0484	heat shock protein binding
AWQ24_01880	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AWQ24_01910	COG0606	chelatase, subunit chli
AWQ24_01930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ24_01935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWQ24_01940	COG0157	Belongs to the NadC ModD family
AWQ24_01965	COG2208	phosphoserine phosphatase activity
AWQ24_01970	COG1216	Glycosyl transferase, family 2
AWQ24_01975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWQ24_01985	COG2010	Cytochrome c
AWQ24_02005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ24_02020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ24_02030	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWQ24_02035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ24_02045	COG0752	glycyl-tRNA synthetase alpha subunit
AWQ24_02060	COG1214	PFAM Peptidase M22, glycoprotease
AWQ24_02065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWQ24_02080	COG1606	tRNA processing
AWQ24_02115	COG0285	dihydrofolate synthase activity
AWQ24_02150	COG0438	transferase activity, transferring glycosyl groups
AWQ24_02205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWQ24_02225	COG0457	Tetratricopeptide repeat
AWQ24_02230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWQ24_02235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ24_02235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ24_02240	COG2205	protein histidine kinase activity
AWQ24_02240	COG3437	response regulator, receiver
AWQ24_02240	COG4999	Histidine kinase
AWQ24_02240	COG3850	Histidine kinase
AWQ24_02250	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWQ24_02255	COG0542	response to heat
AWQ24_02275	COG0339	signal peptide processing
AWQ24_02280	COG0308	aminopeptidase N
AWQ24_02285	COG0673	inositol 2-dehydrogenase activity
AWQ24_02315	COG0360	Binds together with S18 to 16S ribosomal RNA
AWQ24_02320	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWQ24_02325	COG0747	negative chemotaxis
AWQ24_02330	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ24_02330	COG0515	serine threonine protein kinase
AWQ24_02335	COG0072	phenylalanine-tRNA ligase activity
AWQ24_02335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ24_02345	COG4636	protein conserved in cyanobacteria
AWQ24_02350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ24_02355	COG0497	DNA recombination
AWQ24_02360	COG0676	glucose-6-phosphate 1-epimerase activity
AWQ24_02365	COG0631	protein serine/threonine phosphatase activity
AWQ24_02370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ24_02375	COG3937	granule-associated protein
AWQ24_02380	COG0066	3-isopropylmalate dehydratase activity
AWQ24_02385	COG0720	synthase
AWQ24_02390	COG1070	Carbohydrate kinase
AWQ24_02395	COG0515	serine threonine protein kinase
AWQ24_02400	COG2211	Major facilitator Superfamily
AWQ24_02405	COG3659	wide pore channel activity
AWQ24_02430	COG3781	membrane
AWQ24_02435	COG0668	transmembrane transport
AWQ24_02450	COG2308	Evidence 4 Homologs of previously reported genes of
AWQ24_02470	COG0347	Belongs to the P(II) protein family
AWQ24_02480	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWQ24_02485	COG0443	Heat shock 70 kDa protein
AWQ24_02490	COG0612	Peptidase, M16
AWQ24_02510	COG0058	SHG alpha-glucan phosphorylase activity
AWQ24_02520	COG1994	Peptidase M50
AWQ24_02520	COG0517	IMP dehydrogenase activity
AWQ24_02530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWQ24_02535	COG0745	RESPONSE REGULATOR receiver
AWQ24_02545	COG0140	phosphoribosyl-ATP diphosphatase activity
AWQ24_02545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWQ24_02550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWQ24_02555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWQ24_02565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ24_02570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWQ24_02575	COG2314	TM2 domain
AWQ24_02585	COG0745	RESPONSE REGULATOR receiver
AWQ24_02590	COG1126	abc transporter atp-binding protein
AWQ24_02630	COG1943	Transposase
AWQ24_02650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ24_02650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWQ24_02670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWQ24_02675	COG0436	Aminotransferase
AWQ24_02680	COG0850	regulation of cytokinetic process
AWQ24_02685	COG2894	cell division
AWQ24_02690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AWQ24_02700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWQ24_02720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWQ24_02725	COG0671	phosphoesterase, PA-phosphatase related
AWQ24_02730	COG0612	Peptidase, M16
AWQ24_02745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWQ24_02750	COG0416	fatty acid biosynthetic process
AWQ24_02770	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ24_02785	COG4636	protein conserved in cyanobacteria
AWQ24_02790	COG1215	transferase activity, transferring glycosyl groups
AWQ24_02815	COG0484	heat shock protein binding
AWQ24_02840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWQ24_02845	COG0271	Belongs to the BolA IbaG family
AWQ24_02855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ24_02860	COG0613	PHP domain protein
AWQ24_02865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWQ24_02875	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWQ24_02880	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWQ24_02885	COG0235	Class ii aldolase
AWQ24_02900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWQ24_02905	COG0450	alkyl hydroperoxide reductase
AWQ24_02925	COG0159	tryptophan synthase activity
AWQ24_02935	COG4243	Vitamin k epoxide reductase
AWQ24_02940	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWQ24_02975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWQ24_02980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWQ24_02985	COG0557	exoribonuclease II activity
AWQ24_03000	COG0475	glutathione-regulated potassium exporter activity
AWQ24_03005	COG2247	cell wall binding repeat
AWQ24_03005	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWQ24_03010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWQ24_03015	COG0142	geranyltranstransferase activity
AWQ24_03030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ24_03055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ24_03060	COG0798	PFAM Bile acid sodium symporter
AWQ24_03065	COG0640	Transcriptional regulator
AWQ24_03070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ24_03075	COG0750	zinc metalloprotease
AWQ24_03085	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWQ24_03090	COG0149	triose-phosphate isomerase activity
AWQ24_03095	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ24_03095	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ24_03115	COG0018	arginyl-trna synthetase
AWQ24_03125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWQ24_03135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWQ24_03150	COG0371	Dehydrogenase
AWQ24_03155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWQ24_03175	COG0284	orotidine-5'-phosphate decarboxylase activity
AWQ24_03175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ24_03180	COG1136	(ABC) transporter
AWQ24_03180	COG0577	efflux transmembrane transporter activity
AWQ24_03190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWQ24_03200	COG2197	response regulator
AWQ24_03210	COG0251	oxidation-reduction process
AWQ24_03215	COG0513	Belongs to the DEAD box helicase family
AWQ24_03220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ24_03225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWQ24_03230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWQ24_03240	COG0483	inositol monophosphate 1-phosphatase activity
AWQ24_03245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ24_03255	COG0488	(ABC) transporter
AWQ24_03265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWQ24_03270	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AWQ24_03290	COG4139	cobalamin transport
AWQ24_03305	COG4771	TonB-dependent receptor
AWQ24_03315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ24_03335	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ24_03360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWQ24_03360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWQ24_03365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWQ24_03390	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ24_03390	COG0022	dehydrogenase e1 component
AWQ24_03395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ24_03400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ24_03425	COG2072	flavoprotein involved in K transport
AWQ24_03450	COG2144	transferase activity, transferring acyl groups
AWQ24_03480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ24_03490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWQ24_03495	COG1022	Amp-dependent synthetase and ligase
AWQ24_03505	COG0287	Prephenate dehydrogenase
AWQ24_03510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWQ24_03520	COG0633	Ferredoxin
AWQ24_03520	COG3217	Mosc domain protein beta barrel domain protein
AWQ24_03525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ24_03540	COG0189	ligase activity
AWQ24_03545	COG4067	protein conserved in archaea
AWQ24_03545	COG0189	ligase activity
AWQ24_03575	COG1162	GTPase activity
AWQ24_03585	COG0484	heat shock protein binding
AWQ24_03590	COG0443	Heat shock 70 kDa protein
AWQ24_03600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWQ24_03630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ24_03635	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ24_03635	COG0596	Alpha beta hydrolase
AWQ24_03650	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ24_03665	COG0277	FAD linked oxidase domain protein
AWQ24_03670	COG1132	(ABC) transporter
AWQ24_03675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWQ24_03680	COG3064	Membrane
AWQ24_03680	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWQ24_03680	COG1073	alpha beta
AWQ24_03685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWQ24_03690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ24_03700	COG0438	transferase activity, transferring glycosyl groups
AWQ24_03710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWQ24_03715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ24_03735	COG1845	cytochrome c oxidase, subunit III
AWQ24_03740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWQ24_03745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ24_03760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ24_03775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ24_03785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ24_03790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ24_03800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ24_03805	COG0356	it plays a direct role in the translocation of protons across the membrane
AWQ24_03830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWQ24_03835	COG0857	belongs to the CobB CobQ family
AWQ24_03845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ24_03865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWQ24_03875	COG0779	Required for maturation of 30S ribosomal subunits
AWQ24_03880	COG0195	Participates in both transcription termination and antitermination
AWQ24_03890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWQ24_03895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWQ24_03910	COG3639	organic phosphonate transmembrane transporter activity
AWQ24_03920	COG0515	serine threonine protein kinase
AWQ24_03935	COG0429	hydrolase of the alpha beta-hydrolase fold
AWQ24_03940	COG0488	(ABC) transporter
AWQ24_03950	COG0463	Glycosyl transferase, family 2
AWQ24_03955	COG0681	Belongs to the peptidase S26 family
AWQ24_03975	COG0303	'Molybdopterin
AWQ24_03985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWQ24_04025	COG3659	wide pore channel activity
AWQ24_04040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ24_04050	COG1104	cysteine desulfurase activity
AWQ24_04055	COG1530	ribonuclease E activity
AWQ24_04060	COG3956	TIGRFAM MazG family protein
AWQ24_04075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ24_04080	COG0678	peroxiredoxin activity
AWQ24_04085	COG3273	potassium ion transport
AWQ24_04085	COG0471	metal ion transport
AWQ24_04090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWQ24_04095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWQ24_04100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AWQ24_04105	COG4208	sulfate ABC transporter
AWQ24_04110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWQ24_04155	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ24_04155	COG0515	serine threonine protein kinase
AWQ24_04175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ24_04190	COG0105	UTP biosynthetic process
AWQ24_04205	COG2226	methyltransferase
AWQ24_04210	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWQ24_04225	COG1132	(ABC) transporter
AWQ24_04235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWQ24_04240	COG1446	asparaginase
AWQ24_04250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ24_04280	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWQ24_04290	COG0456	acetyltransferase
AWQ24_04295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ24_04295	COG0784	Response regulator, receiver
AWQ24_04295	COG2198	Histidine kinase
AWQ24_04295	COG2205	protein histidine kinase activity
AWQ24_04300	COG2048	Heterodisulfide reductase, subunit B
AWQ24_04315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ24_04320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ24_04325	COG0793	Belongs to the peptidase S41A family
AWQ24_04340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWQ24_04350	COG5001	Diguanylate cyclase
AWQ24_04350	COG4251	negative regulation of phosphorylation
AWQ24_04350	COG2203	Gaf domain
AWQ24_04350	COG3706	GGDEF domain
AWQ24_04365	COG0745	RESPONSE REGULATOR receiver
AWQ24_04370	COG2203	Gaf domain
AWQ24_04375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ24_04380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ24_04395	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AWQ24_04400	COG0745	RESPONSE REGULATOR receiver
AWQ24_04405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ24_04410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ24_04415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ24_04415	COG1116	anion transmembrane transporter activity
AWQ24_04420	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ24_04430	COG2205	protein histidine kinase activity
AWQ24_04440	COG2198	Histidine kinase
AWQ24_04440	COG5002	protein histidine kinase activity
AWQ24_04440	COG0784	Response regulator, receiver
AWQ24_04445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AWQ24_04455	COG3266	domain, Protein
AWQ24_04455	COG0515	serine threonine protein kinase
AWQ24_04465	COG0799	negative regulation of ribosome biogenesis
AWQ24_04470	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ24_04490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWQ24_04495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWQ24_04510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWQ24_04515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWQ24_04520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWQ24_04525	COG0540	Belongs to the ATCase OTCase family
AWQ24_04540	COG0561	phosphatase activity
AWQ24_04540	COG3100	YcgL domain-containing protein
AWQ24_04545	COG0438	transferase activity, transferring glycosyl groups
AWQ24_04550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWQ24_04560	COG0045	succinate-CoA ligase (ADP-forming) activity
AWQ24_04590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWQ24_04605	COG5002	protein histidine kinase activity
AWQ24_04615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_04620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWQ24_04630	COG1691	(AIR) carboxylase
AWQ24_04635	COG0745	RESPONSE REGULATOR receiver
AWQ24_04645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ24_04655	COG1136	(ABC) transporter
AWQ24_04665	COG2166	iron-sulfur cluster assembly
AWQ24_04675	COG0489	protein tyrosine kinase activity
AWQ24_04700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ24_04705	COG4251	negative regulation of phosphorylation
AWQ24_04710	COG1104	cysteine desulfurase activity
AWQ24_04720	COG0713	ATP synthesis coupled electron transport
AWQ24_04725	COG0839	Belongs to the complex I subunit 6 family
AWQ24_04730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_04735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AWQ24_04740	COG1716	ATPase activity
AWQ24_04745	COG0363	glucosamine-6-phosphate deaminase activity
AWQ24_04760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ24_04790	COG0745	RESPONSE REGULATOR receiver
AWQ24_04795	COG1702	phosphate starvation-inducible protein PhoH
AWQ24_04805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ24_04815	COG2310	stress, protein
AWQ24_04825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWQ24_04835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWQ24_04855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ24_04865	COG0233	cytoplasmic translational termination
AWQ24_04870	COG0528	UMP kinase activity
AWQ24_04880	COG0539	negative regulation of cytoplasmic translation
AWQ24_04885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWQ24_04895	COG0564	pseudouridine synthase activity
AWQ24_04935	COG1404	Belongs to the peptidase S8 family
AWQ24_04940	COG0166	Belongs to the GPI family
AWQ24_04965	COG0386	Belongs to the glutathione peroxidase family
AWQ24_04980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ24_04990	COG0434	BtpA family
AWQ24_05000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWQ24_05005	COG0745	RESPONSE REGULATOR receiver
AWQ24_05010	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ24_05010	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ24_05025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AWQ24_05030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ24_05035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ24_05045	COG0594	ribonuclease P activity
AWQ24_05055	COG0706	membrane insertase activity
AWQ24_05070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_05080	COG2205	protein histidine kinase activity
AWQ24_05080	COG0784	Response regulator, receiver
AWQ24_05080	COG5002	protein histidine kinase activity
AWQ24_05090	COG0003	Pfam Anion-transporting ATPase
AWQ24_05100	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ24_05110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ24_05115	COG0025	NhaP-type Na H and K H
AWQ24_05125	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ24_05130	COG0788	formyltetrahydrofolate deformylase activity
AWQ24_05135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWQ24_05170	COG1716	ATPase activity
AWQ24_05185	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ24_05205	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWQ24_05210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ24_05215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWQ24_05220	COG0154	amidase activity
AWQ24_05225	COG0222	ribosome binding
AWQ24_05230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWQ24_05235	COG0081	regulation of translation
AWQ24_05240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWQ24_05245	COG0250	Participates in transcription elongation, termination and antitermination
AWQ24_05250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWQ24_05260	COG0335	large ribosomal subunit rRNA binding
AWQ24_05265	COG3659	wide pore channel activity
AWQ24_05275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWQ24_05280	COG0254	rRNA binding
AWQ24_05285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWQ24_05290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWQ24_05295	COG0101	tRNA pseudouridine synthase activity
AWQ24_05300	COG0203	ribosomal protein L17
AWQ24_05315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWQ24_05325	COG0563	adenylate kinase activity
AWQ24_05330	COG0201	protein transport
AWQ24_05335	COG0200	Binds to the 23S rRNA
AWQ24_05340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWQ24_05345	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWQ24_05350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWQ24_05355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWQ24_05360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWQ24_05365	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWQ24_05370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWQ24_05380	COG0255	Belongs to the universal ribosomal protein uL29 family
AWQ24_05385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWQ24_05390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWQ24_05395	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWQ24_05400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWQ24_05405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWQ24_05420	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWQ24_05425	COG1185	polyribonucleotide nucleotidyltransferase activity
AWQ24_05445	COG0004	ammonium transporteR
AWQ24_05450	COG1012	belongs to the aldehyde dehydrogenase family
AWQ24_05470	COG1012	belongs to the aldehyde dehydrogenase family
AWQ24_05495	COG3688	RNA-binding protein containing a PIN domain
AWQ24_05500	COG2112	serine threonine protein kinase
AWQ24_05510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ24_05520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWQ24_05535	COG4399	Belongs to the UPF0754 family
AWQ24_05540	COG1333	cytochrome c biogenesis protein
AWQ24_05560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ24_05580	COG3338	carbonate dehydratase activity
AWQ24_05590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ24_05600	COG2226	methyltransferase
AWQ24_05625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWQ24_05635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ24_05640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ24_05645	COG0010	Belongs to the arginase family
AWQ24_05655	COG4251	negative regulation of phosphorylation
AWQ24_05665	COG0445	tRNA wobble uridine modification
AWQ24_05670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWQ24_05695	COG1196	nuclear chromosome segregation
AWQ24_05700	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWQ24_05705	COG2226	methyltransferase
AWQ24_05720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWQ24_05735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWQ24_05755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWQ24_05760	COG0616	signal peptide processing
AWQ24_05770	COG0385	Bile acid
AWQ24_05775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWQ24_05795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWQ24_05800	COG0189	ligase activity
AWQ24_05815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWQ24_05855	COG0561	phosphatase activity
AWQ24_05860	COG1982	Orn Lys Arg decarboxylase major
AWQ24_05865	COG0109	protoheme IX farnesyltransferase activity
AWQ24_05870	COG1612	heme a metabolic process
AWQ24_05875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ24_05880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWQ24_05885	COG1845	cytochrome c oxidase, subunit III
AWQ24_05895	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWQ24_05910	COG0629	single-stranded DNA binding
AWQ24_05915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ24_05920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ24_05925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWQ24_05940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWQ24_05945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_05950	COG0668	transmembrane transport
AWQ24_05970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ24_06015	COG0826	peptidase U32
AWQ24_06025	COG1587	Uroporphyrinogen-III synthase
AWQ24_06030	COG0740	serine-type endopeptidase activity
AWQ24_06035	COG0740	serine-type endopeptidase activity
AWQ24_06040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWQ24_06045	COG3118	belongs to the thioredoxin family
AWQ24_06055	COG0583	DNA-binding transcription factor activity
AWQ24_06065	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWQ24_06075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ24_06080	COG0436	Aminotransferase
AWQ24_06095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ24_06115	COG1253	flavin adenine dinucleotide binding
AWQ24_06135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWQ24_06145	COG0525	valine-tRNA ligase activity
AWQ24_06155	COG0772	Belongs to the SEDS family
AWQ24_06200	COG0745	RESPONSE REGULATOR receiver
AWQ24_06205	COG0805	protein transport
AWQ24_06225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWQ24_06245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ24_06275	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AWQ24_06305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ24_06310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWQ24_06315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWQ24_06320	COG2264	protein methyltransferase activity
AWQ24_06335	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ24_06355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWQ24_06360	COG0395	ABC-type sugar transport system, permease component
AWQ24_06365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ24_06380	COG0653	protein targeting
AWQ24_06390	COG2205	protein histidine kinase activity
AWQ24_06390	COG0784	Response regulator, receiver
AWQ24_06390	COG5002	protein histidine kinase activity
AWQ24_06400	COG0592	DNA-directed DNA polymerase activity
AWQ24_06430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWQ24_06435	COG0632	four-way junction helicase activity
AWQ24_06440	COG0305	Participates in initiation and elongation during chromosome replication
AWQ24_06440	COG1372	Participates in initiation and elongation during chromosome replication
AWQ24_06440	COG0305	Participates in initiation and elongation during chromosome replication
AWQ24_06440	COG1372	Participates in initiation and elongation during chromosome replication
AWQ24_06450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWQ24_06455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWQ24_06460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWQ24_06465	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWQ24_06470	COG0024	Methionine aminopeptidase
AWQ24_06475	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWQ24_06485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ24_06485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ24_06490	COG0156	8-amino-7-oxononanoate synthase activity
AWQ24_06505	COG0824	Thioesterase
AWQ24_06510	COG0347	Belongs to the P(II) protein family
AWQ24_06520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWQ24_06525	COG1366	Belongs to the anti-sigma-factor antagonist family
AWQ24_06535	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AWQ24_06540	COG0716	FMN binding
AWQ24_06550	COG0708	Exodeoxyribonuclease III
AWQ24_06555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWQ24_06575	COG0672	)-iron permease
AWQ24_06585	COG1494	fructose-1,6-bisphosphatase
AWQ24_06590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWQ24_06620	COG0745	RESPONSE REGULATOR receiver
AWQ24_06625	COG0719	Fe-S assembly protein
AWQ24_06625	COG1372	Participates in initiation and elongation during chromosome replication
AWQ24_06630	COG0717	Belongs to the dCTP deaminase family
AWQ24_06645	COG2223	nitrite transmembrane transporter activity
AWQ24_06650	COG0243	molybdopterin cofactor binding
AWQ24_06660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWQ24_06665	COG0848	biopolymer transport protein
AWQ24_06670	COG0811	peptide transport
AWQ24_06675	COG0831	urea catabolic process
AWQ24_06685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ24_06685	COG0426	domain, Protein
AWQ24_06705	COG0617	tRNA 3'-terminal CCA addition
AWQ24_06720	COG1192	Involved in chromosome partitioning
AWQ24_06765	COG0393	Putative heavy-metal-binding
AWQ24_06795	COG0187	DNA topoisomerase II activity
AWQ24_06795	COG1372	Participates in initiation and elongation during chromosome replication
AWQ24_06800	COG2046	Belongs to the sulfate adenylyltransferase family
AWQ24_06805	COG0358	DNA primase activity
AWQ24_06830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ24_06840	COG0191	fructose-bisphosphate aldolase activity
AWQ24_06845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWQ24_06850	COG2205	protein histidine kinase activity
AWQ24_06855	COG5001	Diguanylate cyclase
AWQ24_06860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ24_06885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWQ24_06890	COG0519	Catalyzes the synthesis of GMP from XMP
AWQ24_06890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWQ24_06895	COG5002	protein histidine kinase activity
AWQ24_06930	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWQ24_06935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ24_06940	COG0840	transmembrane signaling receptor activity
AWQ24_06950	COG0745	RESPONSE REGULATOR receiver
AWQ24_06965	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AWQ24_06985	COG1178	ABC-type Fe3 transport system permease component
AWQ24_06990	COG0784	Response regulator, receiver
AWQ24_06990	COG2198	Histidine kinase
AWQ24_06990	COG5002	protein histidine kinase activity
AWQ24_07000	COG5002	protein histidine kinase activity
AWQ24_07025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ24_07030	COG2255	four-way junction helicase activity
AWQ24_07050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ24_07080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ24_07085	COG0248	Ppx GppA phosphatase
AWQ24_07090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWQ24_07105	COG5002	protein histidine kinase activity
AWQ24_07110	COG0151	Belongs to the GarS family
AWQ24_07115	COG0392	lysyltransferase activity
AWQ24_07120	COG0587	DNA-directed DNA polymerase activity
AWQ24_07125	COG4636	protein conserved in cyanobacteria
AWQ24_07130	COG2133	pyrroloquinoline quinone binding
AWQ24_07135	COG0163	prenyltransferase activity
AWQ24_07145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWQ24_07150	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AWQ24_07185	COG0504	CTP synthase activity
AWQ24_07195	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWQ24_07200	COG0463	Glycosyl transferase, family 2
AWQ24_07210	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AWQ24_07220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWQ24_07225	COG3536	Protein conserved in bacteria
AWQ24_07260	COG0681	Belongs to the peptidase S26 family
AWQ24_07270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ24_07280	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWQ24_07300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AWQ24_07300	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWQ24_07300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AWQ24_07300	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWQ24_07315	COG0438	transferase activity, transferring glycosyl groups
AWQ24_07325	COG1132	(ABC) transporter
AWQ24_07340	COG5002	protein histidine kinase activity
AWQ24_07345	COG0745	RESPONSE REGULATOR receiver
AWQ24_07360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ24_07375	COG3409	Peptidoglycan-binding domain 1 protein
AWQ24_07375	COG3429	Glucose-6-phosphate dehydrogenase subunit
AWQ24_07380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWQ24_07385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ24_07390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ24_07395	COG0586	Pfam SNARE associated Golgi protein
AWQ24_07405	COG2226	methyltransferase
AWQ24_07410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ24_07410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ24_07425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWQ24_07430	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ24_07445	COG2843	Capsule synthesis protein
AWQ24_07455	COG0667	Aldo Keto reductase
AWQ24_07465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ24_07515	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ24_07550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ24_07565	COG0529	Catalyzes the synthesis of activated sulfate
AWQ24_07570	COG0617	tRNA 3'-terminal CCA addition
AWQ24_07580	COG0175	sulfate reduction
AWQ24_07585	COG0359	binds to the 23S rRNA
AWQ24_07590	COG2199	diguanylate cyclase activity
AWQ24_07595	COG0489	protein tyrosine kinase activity
AWQ24_07630	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AWQ24_07670	COG0438	transferase activity, transferring glycosyl groups
AWQ24_07670	COG0297	glycogen (starch) synthase activity
AWQ24_07680	COG0438	transferase activity, transferring glycosyl groups
AWQ24_07690	COG0463	Glycosyl transferase, family 2
AWQ24_07710	COG0110	maltose O-acetyltransferase activity
AWQ24_07715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWQ24_07725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ24_07735	COG1077	Cell shape determining protein MreB Mrl
AWQ24_07760	COG4636	protein conserved in cyanobacteria
AWQ24_07770	COG0297	glycogen (starch) synthase activity
AWQ24_07780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWQ24_07785	COG0740	serine-type endopeptidase activity
AWQ24_07825	COG0557	exoribonuclease II activity
AWQ24_07835	COG0047	phosphoribosylformylglycinamidine synthase activity
AWQ24_07840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ24_07845	COG0701	Predicted permease
AWQ24_07850	COG0745	RESPONSE REGULATOR receiver
AWQ24_07855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ24_07855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ24_07860	COG2267	carboxylic ester hydrolase activity
AWQ24_07885	COG0095	Lipoate-protein ligase
AWQ24_07900	COG2084	Dehydrogenase
AWQ24_07920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWQ24_07925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWQ24_07940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ24_07945	COG0457	Tetratricopeptide repeat
AWQ24_07960	COG4783	chaperone-mediated protein folding
AWQ24_07975	COG1090	epimerase
AWQ24_07990	COG0628	permease
AWQ24_08000	COG0745	RESPONSE REGULATOR receiver
AWQ24_08005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ24_08035	COG0247	lactate metabolic process
AWQ24_08040	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWQ24_08045	COG0126	phosphoglycerate kinase activity
AWQ24_08050	COG0589	response to stress
AWQ24_08060	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ24_08070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AWQ24_08090	COG0454	-acetyltransferase
AWQ24_08105	COG2890	protein-(glutamine-N5) methyltransferase activity
AWQ24_08145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ24_08150	COG0768	penicillin binding
AWQ24_08155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWQ24_08160	COG0181	hydroxymethylbilane synthase activity
AWQ24_08180	COG3118	belongs to the thioredoxin family
AWQ24_08190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWQ24_08210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWQ24_08215	COG2346	COG2346, Truncated hemoglobins
AWQ24_08220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWQ24_08225	COG1233	COG1233 Phytoene dehydrogenase and related
AWQ24_08230	COG2161	toxin-antitoxin pair type II binding
AWQ24_08235	COG4115	mRNA cleavage
AWQ24_08240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ24_08250	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ24_08255	COG0724	RNA recognition motif
AWQ24_08260	COG0174	glutamine synthetase
AWQ24_08270	COG0583	DNA-binding transcription factor activity
AWQ24_08290	COG2247	cell wall binding repeat
AWQ24_08290	COG2385	sporulation resulting in formation of a cellular spore
AWQ24_08300	COG0217	transcriptional regulatory protein
AWQ24_08305	COG2205	protein histidine kinase activity
AWQ24_08310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWQ24_08320	COG1196	nuclear chromosome segregation
AWQ24_08320	COG0741	lytic transglycosylase activity
AWQ24_08320	COG0739	heme binding
AWQ24_08325	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ24_08330	COG1045	serine acetyltransferase
AWQ24_08355	COG1120	ATPase activity
AWQ24_08360	COG0735	belongs to the Fur family
AWQ24_08380	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ24_08385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWQ24_08390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ24_08400	COG0442	prolyl-tRNA aminoacylation
AWQ24_08405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ24_08410	COG0469	pyruvate kinase activity
AWQ24_08445	COG0515	serine threonine protein kinase
AWQ24_08455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ24_08475	COG0517	IMP dehydrogenase activity
AWQ24_08475	COG1994	Peptidase M50
AWQ24_08485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWQ24_08495	COG4372	Transposase
AWQ24_08600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWQ24_08605	COG0275	rRNA processing
AWQ24_08620	COG0116	Belongs to the methyltransferase superfamily
AWQ24_08625	COG0515	serine threonine protein kinase
AWQ24_08630	COG1049	propionate catabolic process, 2-methylcitrate cycle
AWQ24_08660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWQ24_08665	COG0314	molybdopterin synthase activity
AWQ24_08675	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWQ24_08685	COG0495	leucyl-tRNA aminoacylation
AWQ24_08710	COG2310	stress, protein
AWQ24_08715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ24_08720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ24_08730	COG0328	RNA-DNA hybrid ribonuclease activity
AWQ24_08735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ24_08740	COG0704	Plays a role in the regulation of phosphate uptake
AWQ24_08745	COG0009	L-threonylcarbamoyladenylate synthase
AWQ24_08750	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AWQ24_08770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWQ24_08775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWQ24_08790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWQ24_08795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AWQ24_08795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ24_08800	COG0842	Transport permease protein
AWQ24_08805	COG1129	ABC transporter
AWQ24_08805	COG0842	Transport permease protein
AWQ24_08810	COG1131	(ABC) transporter
AWQ24_08815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ24_08840	COG2815	serine threonine protein kinase
AWQ24_08840	COG0515	serine threonine protein kinase
AWQ24_08845	COG0012	GTP binding
AWQ24_08855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWQ24_08870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ24_08875	COG1121	(ABC) transporter
AWQ24_08880	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWQ24_08890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ24_08890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ24_08895	COG0484	heat shock protein binding
AWQ24_08900	COG3174	membrane
AWQ24_08910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWQ24_08915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AWQ24_08920	COG0426	domain, Protein
AWQ24_08920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ24_08925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWQ24_08935	COG0375	protein maturation
AWQ24_08940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ24_08950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ24_08955	COG1116	anion transmembrane transporter activity
AWQ24_08960	COG0010	Belongs to the arginase family
AWQ24_08970	COG0113	porphobilinogen synthase activity
AWQ24_08995	COG0170	dolichyl monophosphate biosynthetic process
AWQ24_09015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWQ24_09020	COG0512	Glutamine amidotransferase of anthranilate synthase
AWQ24_09020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ24_09025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWQ24_09030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWQ24_09040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ24_09060	COG0582	viral genome integration into host DNA
AWQ24_09185	COG0582	viral genome integration into host DNA
AWQ24_09210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWQ24_09215	COG2226	methyltransferase
AWQ24_09220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ24_09220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWQ24_09225	COG1489	DNA binding
AWQ24_09260	COG2814	Major facilitator Superfamily
AWQ24_09270	COG0515	serine threonine protein kinase
AWQ24_09270	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ24_09275	COG4451	ribulose bisphosphate carboxylase, small
AWQ24_09285	COG1850	ribulose-bisphosphate carboxylase activity
AWQ24_09295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWQ24_09295	COG4451	ribulose bisphosphate carboxylase, small
AWQ24_09300	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AWQ24_09305	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ24_09310	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ24_09315	COG0659	secondary active sulfate transmembrane transporter activity
AWQ24_09320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ24_09325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_09335	COG1166	arginine decarboxylase activity
AWQ24_09345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ24_09350	COG0719	Fe-S assembly protein
AWQ24_09355	COG0396	ATPase activity
AWQ24_09360	COG0719	Fe-S assembly protein
AWQ24_09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ24_09395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWQ24_09405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWQ24_09410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ24_09410	COG2022	thiamine diphosphate biosynthetic process
AWQ24_09420	COG0408	coproporphyrinogen oxidase activity
AWQ24_09425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWQ24_09430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AWQ24_09440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ24_09445	COG0861	Integral membrane protein TerC family
AWQ24_09455	COG2045	Belongs to the ComB family
AWQ24_09470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWQ24_09495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ24_09500	COG0793	Belongs to the peptidase S41A family
AWQ24_09505	COG2052	Domain of unknown function (DUF370)
AWQ24_09510	COG0194	GDP metabolic process
AWQ24_09515	COG0740	serine-type endopeptidase activity
AWQ24_09530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWQ24_09540	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AWQ24_09565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ24_09570	COG0697	spore germination
AWQ24_09585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ24_09595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWQ24_09600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWQ24_09605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWQ24_09675	COG0305	Participates in initiation and elongation during chromosome replication
AWQ24_09675	COG1372	Participates in initiation and elongation during chromosome replication
AWQ24_09730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWQ24_09735	COG2385	sporulation resulting in formation of a cellular spore
AWQ24_09745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWQ24_09760	COG1716	ATPase activity
AWQ24_09760	COG1131	(ABC) transporter
AWQ24_09760	COG0842	Transport permease protein
AWQ24_09770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWQ24_09780	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ24_09785	COG3932	Exopolysaccharide synthesis, ExoD
AWQ24_09795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWQ24_09800	COG0859	PFAM glycosyl transferase family 9
AWQ24_09805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWQ24_09825	COG0723	plastoquinol--plastocyanin reductase activity
AWQ24_09830	COG3258	Cytochrome c
AWQ24_09850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ24_09860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWQ24_09865	COG1799	cell septum assembly
AWQ24_09870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWQ24_09875	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AWQ24_09880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWQ24_09890	COG0037	tRNA processing
AWQ24_09895	COG1191	sigma factor activity
AWQ24_09900	COG0484	heat shock protein binding
AWQ24_09925	COG1801	Protein of unknown function DUF72
AWQ24_09940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ24_09940	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ24_09945	COG1562	ergosterol biosynthetic process
AWQ24_09955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ24_09975	COG0023	Translation Initiation Factor
AWQ24_10000	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AWQ24_10005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ24_10025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ24_10030	COG5002	protein histidine kinase activity
AWQ24_10045	COG2197	response regulator
AWQ24_10050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWQ24_10055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWQ24_10060	COG0052	Belongs to the universal ribosomal protein uS2 family
AWQ24_10070	COG2885	chlorophyll binding
AWQ24_10075	COG2885	chlorophyll binding
AWQ24_10085	COG0628	permease
AWQ24_10090	COG0776	regulation of translation
AWQ24_10100	COG0390	transport system, permease component
AWQ24_10105	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWQ24_10125	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_10135	COG2244	polysaccharide biosynthetic process
AWQ24_10140	COG0438	transferase activity, transferring glycosyl groups
AWQ24_10145	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ24_10155	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ24_10175	COG1666	GTP binding
AWQ24_10180	COG1575	Belongs to the MenA family. Type 1 subfamily
AWQ24_10185	COG0131	Imidazoleglycerol-phosphate dehydratase
AWQ24_10205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ24_10210	COG5398	heme oxygenase
AWQ24_10215	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ24_10220	COG1733	regulation of RNA biosynthetic process
AWQ24_10225	COG0726	polysaccharide deacetylase
AWQ24_10235	COG0411	ABC transporter
AWQ24_10240	COG0288	reversible hydration of carbon dioxide
AWQ24_10255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_10260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ24_10265	COG1420	regulation of RNA biosynthetic process
AWQ24_10290	COG0237	dephospho-CoA kinase activity
AWQ24_10290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ24_10295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ24_10310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ24_10315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ24_10325	COG2363	Small membrane protein
AWQ24_10340	COG0312	modulator of DNA gyrase
AWQ24_10345	COG0747	negative chemotaxis
AWQ24_10360	COG0366	Alpha amylase catalytic
AWQ24_10365	COG3769	mannosylglycerate metabolic process
AWQ24_10425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWQ24_10425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AWQ24_10435	COG0395	ABC-type sugar transport system, permease component
AWQ24_10440	COG1175	transmembrane transport
AWQ24_10445	COG1653	transport
AWQ24_10450	COG3842	ATPase activity
AWQ24_10460	COG1027	Aspartate ammonia-lyase
AWQ24_10470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ24_10475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ24_10480	COG0085	RNA polymerase activity
AWQ24_10485	COG0084	hydrolase, TatD family'
AWQ24_10490	COG0268	Binds directly to 16S ribosomal RNA
AWQ24_10540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ24_10550	COG0051	transcription antitermination factor activity, RNA binding
AWQ24_10555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWQ24_10560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ24_10565	COG0049	tRNA binding
AWQ24_10570	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWQ24_10575	COG0316	Belongs to the HesB IscA family
AWQ24_10585	COG0590	tRNA wobble adenosine to inosine editing
AWQ24_10590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ24_10595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AWQ24_10600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWQ24_10605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ24_10615	COG1597	lipid kinase activity
AWQ24_10625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ24_10645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ24_10665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ24_10685	COG4149	molybdate abc transporter
AWQ24_10695	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWQ24_10710	COG0039	L-malate dehydrogenase activity
AWQ24_10735	COG0418	dihydroorotase activity
AWQ24_10750	COG5002	protein histidine kinase activity
AWQ24_10760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWQ24_10765	COG0210	DNA helicase
AWQ24_10770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ24_10775	COG1131	(ABC) transporter
AWQ24_10785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ24_10800	COG1595	DNA-templated transcription, initiation
AWQ24_10820	COG1252	NADH dehydrogenase
AWQ24_10830	COG0829	nickel cation binding
AWQ24_10850	COG0439	Biotin carboxylase
AWQ24_10870	COG0460	homoserine dehydrogenase
AWQ24_10885	COG4636	protein conserved in cyanobacteria
AWQ24_10935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWQ24_10945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWQ24_10950	COG0589	response to stress
AWQ24_10970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ24_10985	COG4636	protein conserved in cyanobacteria
AWQ24_10995	COG0443	Heat shock 70 kDa protein
AWQ24_11000	COG0484	heat shock protein binding
AWQ24_11005	COG0564	pseudouridine synthase activity
AWQ24_11010	COG0668	transmembrane transport
AWQ24_11030	COG5001	Diguanylate cyclase
AWQ24_11030	COG3300	MHYT domain
AWQ24_11085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ24_11090	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWQ24_11095	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWQ24_11115	COG0463	Glycosyl transferase, family 2
AWQ24_11120	COG0003	Pfam Anion-transporting ATPase
AWQ24_11130	COG0436	Aminotransferase
AWQ24_11135	COG1132	(ABC) transporter
AWQ24_11145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ24_11160	COG0772	Belongs to the SEDS family
AWQ24_11165	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWQ24_11215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWQ24_11225	COG0004	ammonium transporteR
AWQ24_11240	COG0237	dephospho-CoA kinase activity
AWQ24_11245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ24_11250	COG1413	lyase activity
AWQ24_11255	COG1413	lyase activity
AWQ24_11265	COG0824	Thioesterase
AWQ24_11275	COG0537	adenosine 5'-monophosphoramidase activity
AWQ24_11285	COG1131	(ABC) transporter
AWQ24_11330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ24_11335	COG1131	(ABC) transporter
AWQ24_11350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWQ24_11380	COG1192	Involved in chromosome partitioning
AWQ24_11445	COG0193	aminoacyl-tRNA hydrolase activity
AWQ24_11470	COG0454	-acetyltransferase
AWQ24_11480	COG0556	nucleotide-excision repair
AWQ24_11485	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ24_11530	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AWQ24_11535	COG0569	domain protein
AWQ24_11540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWQ24_11555	COG4999	Histidine kinase
AWQ24_11555	COG3437	response regulator, receiver
AWQ24_11555	COG3850	Histidine kinase
AWQ24_11555	COG2205	protein histidine kinase activity
AWQ24_11575	COG0124	histidyl-tRNA synthetase
AWQ24_11585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWQ24_11600	COG2267	carboxylic ester hydrolase activity
AWQ24_11605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ24_11615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWQ24_11620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWQ24_11625	COG0573	inorganic phosphate transmembrane transporter activity
AWQ24_11630	COG0581	inorganic phosphate transmembrane transporter activity
AWQ24_11640	COG0802	atpase or kinase
AWQ24_11655	COG0315	cyclic pyranopterin monophosphate synthase activity
AWQ24_11665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ24_11670	COG3152	Membrane
AWQ24_11680	COG3046	protein related to deoxyribodipyrimidine photolyase
AWQ24_11690	COG0768	penicillin binding
AWQ24_11700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWQ24_11705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ24_11725	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWQ24_11735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWQ24_11740	COG1252	NADH dehydrogenase
AWQ24_11780	COG2217	Heavy metal translocating P-type atpase
AWQ24_11785	COG1836	PFAM Integral membrane protein DUF92
AWQ24_11800	COG0673	inositol 2-dehydrogenase activity
AWQ24_11810	COG0633	Ferredoxin
AWQ24_11815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_11825	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWQ24_11850	COG1215	transferase activity, transferring glycosyl groups
AWQ24_11855	COG0830	nickel cation binding
AWQ24_11870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ24_11890	COG0792	nuclease activity
AWQ24_11900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ24_11905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWQ24_11920	COG0024	Methionine aminopeptidase
AWQ24_11950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AWQ24_11965	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AWQ24_11970	COG0242	peptide deformylase activity
AWQ24_11995	COG0542	response to heat
AWQ24_12000	COG0473	3-isopropylmalate dehydrogenase activity
AWQ24_12010	COG2081	HI0933 family
AWQ24_12020	COG1187	pseudouridine synthase activity
AWQ24_12030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWQ24_12040	COG2226	methyltransferase
AWQ24_12050	COG0539	negative regulation of cytoplasmic translation
AWQ24_12055	COG4251	negative regulation of phosphorylation
AWQ24_12055	COG2203	Gaf domain
AWQ24_12055	COG5001	Diguanylate cyclase
AWQ24_12055	COG3706	GGDEF domain
AWQ24_12060	COG5002	protein histidine kinase activity
AWQ24_12060	COG2205	protein histidine kinase activity
AWQ24_12060	COG0784	Response regulator, receiver
AWQ24_12065	COG0500	methyltransferase
AWQ24_12070	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ24_12075	COG3118	belongs to the thioredoxin family
AWQ24_12085	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AWQ24_12090	COG0659	secondary active sulfate transmembrane transporter activity
AWQ24_12095	COG0475	glutathione-regulated potassium exporter activity
AWQ24_12100	COG1006	Multisubunit Na H antiporter MnhC subunit
AWQ24_12110	COG0651	ATP synthesis coupled electron transport
AWQ24_12145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ24_12150	COG1056	cytidyltransferase-related domain
AWQ24_12150	COG1051	belongs to the nudix hydrolase family
AWQ24_12155	COG0587	DNA-directed DNA polymerase activity
AWQ24_12165	COG1187	pseudouridine synthase activity
AWQ24_12190	COG2010	Cytochrome c
AWQ24_12200	COG0070	glutamate synthase
AWQ24_12200	COG0069	glutamate synthase activity
AWQ24_12200	COG0067	glutamate synthase
AWQ24_12205	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWQ24_12220	COG1234	tRNA 3'-trailer cleavage
AWQ24_12225	COG0196	riboflavin kinase activity
AWQ24_12230	COG0714	Associated with various cellular activities
AWQ24_12245	COG1473	amidohydrolase
AWQ24_12255	COG1605	Chorismate mutase
AWQ24_12255	COG0077	Prephenate dehydratase
AWQ24_12280	COG1480	7TM receptor with intracellular HD hydrolase
AWQ24_12300	COG0435	Glutathione S-transferase
AWQ24_12315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWQ24_12340	COG0443	Heat shock 70 kDa protein
AWQ24_12355	COG0481	GTPase activity
AWQ24_12360	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AWQ24_12365	COG0589	response to stress
AWQ24_12370	COG0659	secondary active sulfate transmembrane transporter activity
AWQ24_12375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWQ24_12390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWQ24_12405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ24_12420	COG0438	transferase activity, transferring glycosyl groups
AWQ24_12435	COG0832	Belongs to the urease beta subunit family
AWQ24_12440	COG1940	carbohydrate kinase activity
AWQ24_12455	COG1309	transcriptional regulator
AWQ24_12460	COG0670	Belongs to the BI1 family
AWQ24_12465	COG0825	malonyl-CoA metabolic process
AWQ24_12470	COG0302	gtp cyclohydrolase
AWQ24_12475	COG1902	pentaerythritol trinitrate reductase activity
AWQ24_12490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ24_12525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWQ24_12530	COG0751	glycine-tRNA ligase activity
AWQ24_12535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWQ24_12540	COG0459	protein refolding
AWQ24_12550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWQ24_12555	COG5001	Diguanylate cyclase
AWQ24_12565	COG1970	mechanosensitive ion channel activity
AWQ24_12575	COG1331	Highly conserved protein containing a thioredoxin domain
AWQ24_12590	COG1410	methionine synthase
AWQ24_12590	COG0646	methionine synthase
AWQ24_12600	COG0017	Asparaginyl-tRNA synthetase
AWQ24_12605	COG0431	NADPH-dependent FMN reductase
AWQ24_12620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWQ24_12630	COG0438	transferase activity, transferring glycosyl groups
AWQ24_12640	COG0644	oxidoreductase
AWQ24_12655	COG0575	Belongs to the CDS family
AWQ24_12695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWQ24_12700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWQ24_12725	COG0612	Peptidase, M16
AWQ24_12735	COG0432	Pfam Uncharacterised protein family UPF0047
AWQ24_12750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ24_12755	COG1121	(ABC) transporter
AWQ24_12770	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ24_12775	COG2205	protein histidine kinase activity
AWQ24_12775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWQ24_12780	COG0505	Belongs to the CarA family
AWQ24_12785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ24_12785	COG0758	DNA mediated transformation
AWQ24_12790	COG1840	ABC-type Fe3 transport system, periplasmic component
AWQ24_12795	COG5398	heme oxygenase
AWQ24_12805	COG2268	Band 7 protein
AWQ24_12820	COG0484	heat shock protein binding
AWQ24_12825	COG1690	Belongs to the RtcB family
AWQ24_12830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWQ24_12835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWQ24_12845	COG0300	oxidoreductase activity
AWQ24_12845	COG3000	fatty acid hydroxylase
AWQ24_12860	COG3411	Ferredoxin
AWQ24_12865	COG2197	response regulator
AWQ24_12875	COG1058	Belongs to the CinA family
AWQ24_12875	COG1546	Belongs to the CinA family
AWQ24_12880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWQ24_12920	COG0745	RESPONSE REGULATOR receiver
AWQ24_12930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ24_12945	COG0616	signal peptide processing
AWQ24_12950	COG0697	spore germination
AWQ24_12960	COG0649	NAD binding
AWQ24_12965	COG0571	ribonuclease III activity
AWQ24_12970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ24_12980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ24_12985	COG1754	DNA topoisomerase type I activity
AWQ24_12985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWQ24_12990	COG1007	ATP synthesis coupled electron transport
AWQ24_13000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWQ24_13005	COG0601	transmembrane transport
AWQ24_13040	COG2211	Major facilitator Superfamily
AWQ24_13045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ24_13050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWQ24_13055	COG0406	alpha-ribazole phosphatase activity
AWQ24_13060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWQ24_13075	COG0640	Transcriptional regulator
AWQ24_13080	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AWQ24_13100	COG1053	succinate dehydrogenase
AWQ24_13115	COG2373	Large extracellular alpha-helical protein
AWQ24_13130	COG5002	protein histidine kinase activity
AWQ24_13140	COG0612	Peptidase, M16
AWQ24_13155	COG0668	transmembrane transport
AWQ24_13160	COG1193	negative regulation of DNA recombination
AWQ24_13190	COG5001	Diguanylate cyclase
AWQ24_13190	COG3300	MHYT domain
AWQ24_13195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ24_13200	COG3347	Dehydrogenase
AWQ24_13200	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ24_13215	COG0484	heat shock protein binding
AWQ24_13225	COG0840	transmembrane signaling receptor activity
AWQ24_13225	COG2203	Gaf domain
AWQ24_13240	COG0784	Response regulator, receiver
AWQ24_13245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ24_13250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWQ24_13255	COG3693	PFAM glycoside hydrolase, family 10
AWQ24_13280	COG2217	Heavy metal translocating P-type atpase
AWQ24_13290	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ24_13295	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ24_13300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ24_13340	COG2062	phosphohistidine phosphatase, SixA
AWQ24_13345	COG0372	Belongs to the citrate synthase family
AWQ24_13355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ24_13365	COG0419	ATPase involved in DNA repair
AWQ24_13395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ24_13400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWQ24_13420	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AWQ24_13440	COG4948	Mandelate Racemase Muconate Lactonizing
AWQ24_13450	COG4999	Histidine kinase
AWQ24_13450	COG3437	response regulator, receiver
AWQ24_13450	COG2205	protein histidine kinase activity
AWQ24_13450	COG3850	Histidine kinase
AWQ24_13465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ24_13490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWQ24_13495	COG2200	EAL domain
AWQ24_13500	COG0523	cobalamin synthesis protein
AWQ24_13510	COG3128	pkhd-type hydroxylase
AWQ24_13535	COG2193	ferroxidase activity
AWQ24_13540	COG0572	uridine kinase
AWQ24_13550	COG0415	Belongs to the DNA photolyase family
AWQ24_13560	COG0596	Alpha beta hydrolase
AWQ24_13595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ24_13630	COG2319	Wd-40 repeat
AWQ24_13630	COG4249	Peptidase C14 caspase catalytic subunit p20
AWQ24_13660	COG0589	response to stress
AWQ24_13665	COG1672	PFAM Archaeal ATPase
AWQ24_13670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWQ24_13680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ24_13685	COG0330	HflC and HflK could
AWQ24_13710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWQ24_13715	COG2267	carboxylic ester hydrolase activity
AWQ24_13720	COG0440	acetolactate synthase activity
AWQ24_13730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ24_13745	COG0482	sulfurtransferase activity
AWQ24_13750	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AWQ24_13765	COG0237	dephospho-CoA kinase activity
AWQ24_13780	COG0237	dephospho-CoA kinase activity
AWQ24_13790	COG1741	Belongs to the pirin family
AWQ24_13795	COG0583	DNA-binding transcription factor activity
AWQ24_13810	COG1127	ABC transporter
AWQ24_13825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWQ24_13830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AWQ24_13835	COG1122	ATPase activity
AWQ24_13865	COG0515	serine threonine protein kinase
AWQ24_13865	COG3266	domain, Protein
AWQ24_13880	COG0668	transmembrane transport
AWQ24_13885	COG2226	methyltransferase
AWQ24_13900	COG3012	SEC-C Motif Domain Protein
AWQ24_13910	COG0709	Synthesizes selenophosphate from selenide and ATP
AWQ24_13925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_13930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_13935	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ24_13940	COG2319	Wd-40 repeat
AWQ24_13945	COG3659	wide pore channel activity
AWQ24_13960	COG0004	ammonium transporteR
AWQ24_13965	COG3239	Fatty acid desaturase
AWQ24_13975	COG2119	membrane
AWQ24_13985	COG1473	amidohydrolase
AWQ24_13995	COG5001	Diguanylate cyclase
AWQ24_13995	COG1716	ATPase activity
AWQ24_14000	COG2304	oxidoreductase activity
AWQ24_14005	COG2501	S4 domain
AWQ24_14010	COG0412	Dienelactone hydrolase
AWQ24_14025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWQ24_14030	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AWQ24_14035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWQ24_14045	COG1012	belongs to the aldehyde dehydrogenase family
AWQ24_14065	COG0686	Belongs to the AlaDH PNT family
AWQ24_14075	COG0582	viral genome integration into host DNA
AWQ24_14090	COG0625	glutathione transferase activity
AWQ24_14100	COG0343	queuine tRNA-ribosyltransferase activity
AWQ24_14110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AWQ24_14145	COG1132	(ABC) transporter
AWQ24_14150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWQ24_14155	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ24_14165	COG0552	protein localization to endoplasmic reticulum
AWQ24_14170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ24_14175	COG0415	Belongs to the DNA photolyase family
AWQ24_14180	COG0028	Belongs to the TPP enzyme family
AWQ24_14200	COG2442	InterPro IPR007367
AWQ24_14215	COG4968	Prepilin-type N-terminal cleavage methylation domain
AWQ24_14220	COG2852	Protein conserved in bacteria
AWQ24_14225	COG0137	argininosuccinate synthase activity
AWQ24_14230	COG1234	tRNA 3'-trailer cleavage
AWQ24_14250	COG0312	modulator of DNA gyrase
AWQ24_14255	COG2154	pterin-4-alpha-carbinolamine dehydratase
AWQ24_14260	COG3659	wide pore channel activity
AWQ24_14265	COG2084	Dehydrogenase
AWQ24_14270	COG5001	Diguanylate cyclase
AWQ24_14270	COG4251	negative regulation of phosphorylation
AWQ24_14270	COG2203	Gaf domain
AWQ24_14270	COG3706	GGDEF domain
AWQ24_14275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ24_14290	COG1543	Belongs to the glycosyl hydrolase 57 family
AWQ24_14300	COG1950	PFAM Membrane protein of
AWQ24_14310	COG3339	Conserved Protein
AWQ24_14320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWQ24_14325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWQ24_14340	COG4956	integral membrane protein (PIN domain superfamily)
AWQ24_14345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ24_14350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ24_14365	COG4251	negative regulation of phosphorylation
AWQ24_14400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWQ24_14415	COG2211	Major facilitator Superfamily
AWQ24_14460	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AWQ24_14465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWQ24_14470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWQ24_14475	COG0135	phosphoribosylanthranilate isomerase activity
AWQ24_14480	COG0746	molybdenum cofactor guanylyltransferase activity
AWQ24_14490	COG1672	PFAM Archaeal ATPase
AWQ24_14490	COG2319	Wd-40 repeat
AWQ24_14530	COG0668	transmembrane transport
AWQ24_14545	COG3954	Phosphoribulokinase
AWQ24_14550	COG0277	FAD linked oxidase domain protein
AWQ24_14575	COG2203	Gaf domain
AWQ24_14575	COG5001	Diguanylate cyclase
AWQ24_14575	COG4251	negative regulation of phosphorylation
AWQ24_14575	COG3706	GGDEF domain
AWQ24_14580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWQ24_14590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ24_14595	COG0730	response to heat
AWQ24_14610	COG2304	oxidoreductase activity
AWQ24_14615	COG0215	cysteine-tRNA ligase activity
AWQ24_14745	COG1192	Involved in chromosome partitioning
AWQ24_14755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AWQ24_14760	COG0732	type I restriction modification DNA specificity domain
AWQ24_14770	COG3744	PilT protein domain protein
AWQ24_14795	COG1061	Type III restriction enzyme res subunit
AWQ24_14835	COG1192	Involved in chromosome partitioning
AWQ24_14845	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AWQ24_14890	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AWQ24_14920	COG4974	Belongs to the 'phage' integrase family
AWQ24_14930	COG1192	Involved in chromosome partitioning
AWQ24_15140	COG1116	anion transmembrane transporter activity
AWQ24_15145	COG3659	wide pore channel activity
AWQ24_15150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ24_15155	COG3932	Exopolysaccharide synthesis, ExoD
AWQ24_15160	COG1116	anion transmembrane transporter activity
AWQ24_15160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ24_15165	COG1116	anion transmembrane transporter activity
AWQ24_15165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ24_15170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ24_15180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AWQ24_15280	COG2205	protein histidine kinase activity
AWQ24_15285	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AWQ24_15300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AWQ24_15305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AWQ24_15310	COG2205	protein histidine kinase activity
AWQ24_15320	COG0842	Transport permease protein
AWQ24_15325	COG1131	(ABC) transporter
AWQ24_15330	COG1846	Transcriptional regulator
AWQ24_15340	COG0737	Belongs to the 5'-nucleotidase family
AWQ24_15385	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWQ24_15400	COG0723	plastoquinol--plastocyanin reductase activity
AWQ24_15410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ24_15415	COG1120	ATPase activity
AWQ24_15430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ24_15455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ24_15460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWQ24_15475	COG2124	cytochrome p450
AWQ24_15590	COG0405	Gamma-glutamyltransferase
AWQ24_15595	COG0848	biopolymer transport protein
AWQ24_15600	COG0811	peptide transport
AWQ24_15615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ24_15625	COG2304	oxidoreductase activity
AWQ24_15630	COG0515	serine threonine protein kinase
AWQ24_15640	COG2314	TM2 domain
AWQ24_15675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWQ24_15685	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ24_15695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWQ24_15725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ24_15735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ24_15740	COG5002	protein histidine kinase activity
AWQ24_15740	COG3447	MASE1 domain protein
AWQ24_15740	COG5001	Diguanylate cyclase
AWQ24_15745	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AWQ24_15750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AWQ24_15770	COG0745	RESPONSE REGULATOR receiver
AWQ24_15775	COG5002	protein histidine kinase activity
AWQ24_15775	COG3850	Histidine kinase
AWQ24_15795	COG0398	Pfam SNARE associated Golgi protein
AWQ24_15800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family