locus-tag	class	description
BM449_00010	ENOG4105C0H	protease
BM449_00020	ENOG4107WJM	-acetyltransferase
BM449_00025	ENOG4108YIQ	Alpha beta hydrolase
BM449_00030	ENOG4105BZ1	(ABC) transporter
BM449_00035	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BM449_00040	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BM449_00045	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM449_00155	ENOG4108I5C	dEAD DEAH box helicase
BM449_00195	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
BM449_00235	ENOG4105EW6	flavin reductase domain protein, FMN-binding
BM449_00590	ENOG4105VUH	addiction module killer protein
BM449_00595	ENOG4105YES	addiction module antidote protein
BM449_00605	ENOG4108KQ5	Integrase catalytic subunit
BM449_00670	ENOG4105F2I	Transposase
BM449_00680	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
BM449_00710	ENOG41065W4	chlorophyll a b binding light harvesting protein
BM449_00720	ENOG4108S1Y	allophycocyanin alpha-B chain
BM449_00760	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BM449_00780	ENOG4105CMQ	Chloride channel
BM449_00785	ENOG4105CZQ	inner membrane transport protein YdhC
BM449_00810	ENOG4108KQ5	Integrase catalytic subunit
BM449_00815	ENOG4105C09	Bile acid
BM449_00845	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM449_00870	ENOG4105YES	addiction module antidote protein
BM449_00875	ENOG4105VUH	addiction module killer protein
BM449_00890	ENOG410607W	Transposase
BM449_00895	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM449_00900	ENOG410607W	Transposase
BM449_00905	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM449_00915	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
BM449_00960	ENOG4105HF0	Membrane
BM449_00965	ENOG4108V62	Rhodanese domain protein
BM449_00990	ENOG4105WZW	rhodanese family
BM449_00995	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
BM449_01020	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BM449_01025	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM449_01040	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BM449_01070	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BM449_01105	ENOG4105CVR	type I restriction-modification system
BM449_01110	ENOG4105EKX	Restriction modification system DNA (Specificity
BM449_01180	ENOG4105DZR	Type I site-specific deoxyribonuclease
BM449_01185	ENOG4105CSR	polyphosphate kinase 2
BM449_01205	ENOG4108QF0	This is one of the two reaction center proteins of photosystem II
BM449_01235	ENOG4105C59	p-type ATPase
BM449_01285	ENOG4105CJ1	ABC, transporter
BM449_01295	ENOG4105EGS	Mechanosensitive ion channel
BM449_01325	ENOG410607W	Transposase
BM449_01330	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM449_01415	ENOG4108594	Permease of the drug metabolite transporter
BM449_01445	ENOG4105ETX	regulatoR
BM449_01450	ENOG4105GR3	Histidine kinase
BM449_01510	ENOG4108KQ5	Integrase catalytic subunit
BM449_01530	ENOG4105F9F	transposase
BM449_01620	ENOG4107R1Y	fructose-bisphosphate aldolase
BM449_01625	ENOG4107T0X	DNA ligase
BM449_01635	ENOG4107CUI	carotenoid binding protein
BM449_01650	ENOG4105C09	Bile acid
BM449_01655	ENOG4107T0X	DNA ligase
BM449_01660	ENOG4107QRT	dEAD DEAH box helicase
BM449_01675	ENOG4105CYM	Glutathione S-transferase
BM449_01685	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BM449_01690	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BM449_01700	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BM449_01720	ENOG4105C9Q	fumarate hydratase class II
BM449_01745	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BM449_01760	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BM449_01765	ENOG4105D8X	mechanosensitive ion channel
BM449_01775	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM449_01780	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BM449_01785	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
BM449_01795	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BM449_01800	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BM449_01820	ENOG4105DJZ	UPF0182 protein
BM449_01825	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
BM449_01840	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BM449_01845	ENOG41068G9	50S ribosomal protein L32
BM449_01855	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BM449_01900	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
BM449_01915	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BM449_01960	ENOG4106FC9	Protein  of unknown function (DUF3018)
BM449_01965	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
BM449_01980	ENOG4107QIV	Cytochrome c biogenesis protein
BM449_01985	ENOG4105CHH	sulfate transporter
BM449_02025	ENOG41076WT	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II (By similarity)
BM449_02030	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BM449_02085	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BM449_02105	ENOG4108R1E	Serine threonine protein phosphatase 1
BM449_02115	ENOG4107QKA	exodeoxyribonuclease V beta
BM449_02120	ENOG4105C7H	Helicase, RecD TraA family
BM449_02140	ENOG4105C1J	atp-dependent rna helicase
BM449_02160	ENOG4105BZ1	(ABC) transporter
BM449_02170	ENOG4108RCF	TRANSCRIPTIONal
BM449_02175	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
BM449_02185	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BM449_02190	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BM449_02200	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BM449_02225	ENOG4105C72	UPF0176 protein
BM449_02230	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BM449_02235	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BM449_02240	ENOG4105C8B	TIGR00159 family
BM449_02290	ENOG4105CXN	decarboxylase
BM449_02305	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_02320	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
BM449_02325	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
BM449_02340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BM449_02350	ENOG4105CD8	aminopeptidase N
BM449_02365	ENOG4105BZU	Histidine kinase
BM449_02380	ENOG4107SC0	ferredoxin--NADP reductase
BM449_02390	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
BM449_02395	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BM449_02400	ENOG4108ZM9	phosphoglycerate mutase
BM449_02410	ENOG4107QYX	exodeoxyribonuclease v alpha
BM449_02425	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BM449_02435	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
BM449_02490	ENOG4105BZ1	(ABC) transporter
BM449_02500	ENOG4105CP7	Triose-phosphate isomerase
BM449_02515	ENOG4105CJ1	ABC, transporter
BM449_02520	ENOG4105CJ1	ABC, transporter
BM449_02525	ENOG4107QWP	ABC-2 type transporter
BM449_02535	ENOG4105F32	YngK protein
BM449_02545	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BM449_02560	ENOG4105CHF	Glutathione S-transferase
BM449_02565	ENOG4105CTK	cobaltochelatase, cobn subunit
BM449_02570	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BM449_02580	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BM449_02625	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BM449_02630	ENOG4105E0F	Histidine kinase
BM449_02635	ENOG4105CSR	polyphosphate kinase 2
BM449_02665	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM449_02670	ENOG4105D3Q	Sugar transferase
BM449_02685	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BM449_02690	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BM449_02715	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BM449_02735	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BM449_02740	ENOG4105DTQ	mandelate racemase muconate lactonizing
BM449_02760	ENOG4107TTD	cytosine deaminase
BM449_02775	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BM449_02780	ENOG4105C8Y	Acetylornithine aminotransferase
BM449_02785	ENOG4105C8Y	Acetylornithine aminotransferase
BM449_02790	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BM449_02815	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BM449_02825	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BM449_02830	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BM449_02840	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BM449_02850	ENOG4105C3J	Cysteine desulfurase
BM449_02860	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BM449_02870	ENOG4107RIX	inner membrane protein translocase component YidC
BM449_02880	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BM449_02910	ENOG4105Q84	sucrose synthase
BM449_02930	ENOG4105K63	Thioredoxin
BM449_02935	ENOG4105CHM	Aminotransferase
BM449_02940	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BM449_02945	ENOG4105DR5	peptidase
BM449_02950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BM449_02960	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BM449_02995	ENOG4108R6K	riboflavin synthase, subunit alpha
BM449_03030	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BM449_03050	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BM449_03055	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BM449_03070	ENOG4107SVH	Potassium channel protein
BM449_03080	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BM449_03095	ENOG4105C9X	ppx gppa phosphatase
BM449_03115	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
BM449_03125	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
BM449_03130	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
BM449_03145	ENOG4105F23	Fibronectin-binding protein
BM449_03150	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BM449_03155	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
BM449_03165	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BM449_03185	ENOG4105C3G	gtp-binding protein
BM449_03220	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BM449_03225	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BM449_03230	ENOG4108J59	Extracellular solute-binding protein, family 5
BM449_03260	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BM449_03265	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BM449_03285	ENOG4106FVC	RNA methyltransferase
BM449_03300	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BM449_03305	ENOG4108URH	decarboxylase
BM449_03310	ENOG4105K63	Thioredoxin
BM449_03315	ENOG4107QVP	Dehydrogenase
BM449_03320	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BM449_03335	ENOG4108JT6	LycopEne
BM449_03345	ENOG4107RFW	hydrolase family 57
BM449_03355	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BM449_03360	ENOG4105DRS	transport system, permease
BM449_03380	ENOG4107TS3	membrane protein, TerC
BM449_03410	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BM449_03415	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BM449_03425	ENOG4107T9Q	phosphonate abc transporter
BM449_03430	ENOG4105D5T	phosphonate abc transporter
BM449_03435	ENOG4105S7S	phosphonate abc transporter
BM449_03445	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_03470	ENOG4108JJB	ABC transporter
BM449_03475	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BM449_03490	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BM449_03495	ENOG4107VC8	ATP cone domain protein
BM449_03515	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BM449_03520	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BM449_03530	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BM449_03565	ENOG4105C6K	Malic enzyme
BM449_03575	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BM449_03580	ENOG4105W8H	transhydrogenase (subunit alpha
BM449_03585	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BM449_03595	ENOG4105C1J	atp-dependent rna helicase
BM449_03605	ENOG4107RIQ	Sulfate adenylate transferase
BM449_03610	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BM449_03615	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
BM449_03635	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BM449_03650	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BM449_03660	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
BM449_03665	ENOG4108JQC	penicillin-binding protein 1A
BM449_03675	ENOG41080UX	Methyltransferase
BM449_03680	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
BM449_03705	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM449_03710	ENOG41062D9	Histidine kinase
BM449_03750	ENOG41083MR	nifu domain-containing protein
BM449_03755	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BM449_03760	ENOG4105DZP	Membrane-associated zinc metalloprotease
BM449_03770	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BM449_03775	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BM449_03810	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BM449_03815	ENOG4105K70	DNA-binding protein
BM449_03820	ENOG4108IUM	Glycogen debranching enzyme
BM449_03825	ENOG4105DKW	ABC transporter
BM449_03870	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BM449_03880	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BM449_03895	ENOG4107U45	Cobalt transport protein
BM449_03920	ENOG4105DVK	Precorrin-2 c20-methyltransferase
BM449_03935	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BM449_03965	ENOG4105C26	Dehydrogenase
BM449_03975	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BM449_03985	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BM449_03990	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BM449_03995	ENOG4105CG3	alpha amylase, catalytic region
BM449_04000	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM449_04005	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
BM449_04015	ENOG4107T3P	ABC, transporter
BM449_04030	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
BM449_04055	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BM449_04060	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
BM449_04065	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
BM449_04095	ENOG4105ECY	inositol monophosphatase
BM449_04115	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BM449_04125	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
BM449_04130	ENOG4108IYU	L-aspartate oxidase
BM449_04135	ENOG4105CVB	Vitamin K epoxide reductase
BM449_04145	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BM449_04185	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BM449_04205	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BM449_04210	ENOG4105D17	glycoside hydrolase, family 3 domain protein
BM449_04220	ENOG4107TVC	Glycosyl transferase, family 2
BM449_04225	ENOG4108DIF	synthase (EC 4.2.1.75)
BM449_04240	ENOG4105CVN	desaturase
BM449_04270	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
BM449_04275	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BM449_04280	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BM449_04285	ENOG4108PWY	Carbohydrate-selective porin OprB
BM449_04290	ENOG4108PWY	Carbohydrate-selective porin OprB
BM449_04315	ENOG4105VUV	UPF0367 protein
BM449_04320	ENOG4108JJB	ABC transporter
BM449_04330	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM449_04335	ENOG4107QRG	dna polymerase iii
BM449_04340	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BM449_04345	ENOG4105C59	p-type ATPase
BM449_04350	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
BM449_04370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BM449_04390	ENOG41072GX	Peptidase M22 Glycoprotease
BM449_04400	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BM449_04415	ENOG4105FE1	phytoene synthase
BM449_04420	ENOG4105CVN	desaturase
BM449_04425	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BM449_04435	ENOG4105DUM	transcriptional regulator, lysR family
BM449_04450	ENOG4105C8S	subunit m
BM449_04475	ENOG4108Q9V	regulatoR
BM449_04485	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BM449_04490	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BM449_04500	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BM449_04505	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BM449_04525	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BM449_04530	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BM449_04540	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BM449_04575	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BM449_04585	ENOG4105C3J	Cysteine desulfurase
BM449_04635	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
BM449_04650	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BM449_04675	ENOG4105VN1	Heat shock protein
BM449_04680	ENOG41089TF	bicarbonate transport system substrate-binding protein
BM449_04685	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
BM449_04695	ENOG4105K3M	)-transporter
BM449_04730	ENOG4105CNW	domain protein
BM449_04760	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BM449_04765	ENOG4105CXI	aluminum resistance protein
BM449_04785	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BM449_04790	ENOG4105CDU	Replicative dna helicase
BM449_04790	ENOG4105CDU	Replicative dna helicase
BM449_04800	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BM449_04825	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BM449_04860	ENOG4105ENH	Sulfatase
BM449_04865	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BM449_04880	ENOG4105E18	UPF0276 protein
BM449_04915	ENOG4105CKI	cobalamin synthesis protein
BM449_04955	ENOG4105FDK	ABC transporter
BM449_04975	ENOG4105CKI	cobalamin synthesis protein
BM449_04995	ENOG4105DWV	Homoserine O-trans-acetylase
BM449_05015	ENOG4105DC8	reductase
BM449_05040	ENOG4105Q84	sucrose synthase
BM449_05045	ENOG4107QW3	Sucrose phosphorylase
BM449_05075	ENOG4105CHH	sulfate transporter
BM449_05085	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BM449_05105	ENOG41063FQ	CsbD-like protein
BM449_05115	ENOG4105C26	Dehydrogenase
BM449_05120	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BM449_05125	ENOG41063FQ	CsbD-like protein
BM449_05155	ENOG4105XEV	csbD-like
BM449_05160	ENOG4105BZU	Histidine kinase
BM449_05165	ENOG4105BZU	Histidine kinase
BM449_05175	ENOG4105E18	UPF0276 protein
BM449_05195	ENOG4105DXN	mazG family
BM449_05200	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BM449_05205	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BM449_05210	ENOG4105CYW	agmatinase
BM449_05220	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BM449_05225	ENOG4105C9M	aspartyl-trna synthetase
BM449_05240	ENOG4107U96	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BM449_05250	ENOG4105CUT	histidyl-tRNA synthetase
BM449_05255	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BM449_05265	ENOG4105YEU	This protein is a component of the reaction center of photosystem II (By similarity)
BM449_05275	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
BM449_05280	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
BM449_05285	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
BM449_05290	ENOG410828V	rubredoxin
BM449_05295	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BM449_05300	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BM449_05305	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BM449_05310	ENOG4105CHW	UPF0052 protein
BM449_05315	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM449_05325	ENOG4105EET	magnesium chelatase
BM449_05380	ENOG4105C5I	Dehydrogenase
BM449_05435	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BM449_05525	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BM449_05585	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BM449_05595	ENOG4108YZ4	nudix hydrolase
BM449_05600	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM449_05625	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
BM449_05635	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BM449_05710	ENOG4105E6M	Sulphatase-modifying factor protein
BM449_05715	ENOG41061MV	Arylsulfatase
BM449_05730	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BM449_05735	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BM449_05755	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BM449_05790	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BM449_05855	ENOG4105CG3	alpha amylase, catalytic region
BM449_05860	ENOG4105CG3	alpha amylase, catalytic region
BM449_05875	ENOG4105C59	p-type ATPase
BM449_05895	ENOG4107QJZ	Glycosyl transferase, family 2
BM449_05920	ENOG4107QN2	dihydrolipoyl dehydrogenase
BM449_05935	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_05945	ENOG4105P8Q	Curli production assembly transport component CsgG
BM449_05955	ENOG4107QYG	anthranilate phosphoribosyltransferase
BM449_05965	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BM449_05970	ENOG4107R3J	Transporter
BM449_05975	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BM449_05985	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BM449_05990	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
BM449_06000	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BM449_06010	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BM449_06015	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BM449_06020	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BM449_06025	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BM449_06030	ENOG410870F	Cyclic nucleotide-binding protein
BM449_06040	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BM449_06050	ENOG4105C0D	helicase
BM449_06060	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BM449_06100	ENOG4105VUH	addiction module killer protein
BM449_06105	ENOG4105YES	addiction module antidote protein
BM449_06135	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BM449_06145	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
BM449_06160	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BM449_06165	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BM449_06170	ENOG4107Z3D	50S ribosomal protein l10
BM449_06175	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BM449_06190	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BM449_06210	ENOG4105GVR	general secretion pathway protein D
BM449_06220	ENOG4107QZB	decarboxylase
BM449_06225	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BM449_06235	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM449_06245	ENOG4105BZA	Phosphoglycerate kinase
BM449_06255	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BM449_06265	ENOG4105CMQ	Chloride channel
BM449_06270	ENOG4108JQ6	ABC transporter
BM449_06280	ENOG4105CNG	UPF0061 protein
BM449_06295	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BM449_06320	ENOG4105C75	arginyL-tRNA synthetase
BM449_06325	ENOG4105VT2	5-hydroxyisourate hydrolase
BM449_06350	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM449_06355	ENOG4105D78	K07001 NTE family protein
BM449_06365	ENOG4105D64	Mechanosensitive ion channel
BM449_06375	ENOG4105EXU	Membrane
BM449_06380	ENOG4105C5X	domain protein
BM449_06415	ENOG4105DDQ	anthranilate synthase
BM449_06425	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BM449_06435	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BM449_06445	ENOG4105D7Z	glutathione synthase
BM449_06470	ENOG41089UC	methyltransferase, type 11
BM449_06480	ENOG4108ZAF	Molybdopterin
BM449_06485	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BM449_06490	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BM449_06500	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BM449_06505	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_06520	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BM449_06530	ENOG4105CMQ	Chloride channel
BM449_06560	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BM449_06565	ENOG4105CFG	Acts as a chaperone (By similarity)
BM449_06570	ENOG4105E2X	shikimate dehydrogenase
BM449_06580	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
BM449_06585	ENOG4105CDH	Citrulline--aspartate ligase
BM449_06600	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BM449_06615	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BM449_06660	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BM449_06670	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
BM449_06675	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BM449_06680	ENOG4108R3E	Dna-3-methyladenine glycosylase i
BM449_06685	ENOG4108KQ5	Integrase catalytic subunit
BM449_06695	ENOG4105EU8	FAD linked oxidase domain protein
BM449_06730	ENOG4107QRI	Phosphoketolase
BM449_06740	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BM449_06765	ENOG4105D9N	nucleoside
BM449_06795	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
BM449_06800	ENOG4105XMH	SpoVT AbrB domain protein
BM449_06805	ENOG4107R3N	Filamentation induced by cAMP protein fic
BM449_06820	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BM449_06840	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
BM449_06845	ENOG4105CMR	udp-glucose 4-epimerase
BM449_06875	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BM449_06885	ENOG4105TMB	Formate nitrite transporter
BM449_06890	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
BM449_06900	ENOG4105KI2	Urea amidohydrolase subunit beta
BM449_06905	ENOG4108YZ9	Urea amidohydrolase subunit gamma
BM449_06925	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BM449_06930	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
BM449_06935	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
BM449_06940	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
BM449_06945	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
BM449_06950	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
BM449_06955	ENOG4105C32	Amino acid ABC transporter (Permease)
BM449_06965	ENOG4105C0Z	ABC transporter
BM449_06970	ENOG4108IV0	ABC, transporter
BM449_06985	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BM449_06990	ENOG4105CRQ	synthase (Component I)
BM449_06995	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BM449_07010	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
BM449_07040	ENOG4105CRK	lysyL-tRNA synthetase
BM449_07045	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM449_07050	ENOG4107T3P	ABC, transporter
BM449_07070	ENOG41080E3	single-stranded DNA-binding protein
BM449_07075	ENOG4107T5V	SNARE associated Golgi
BM449_07080	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BM449_07085	ENOG4105K8N	protein family UPF0079, ATPase
BM449_07090	ENOG4105D7K	pfkb domain protein
BM449_07110	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_07115	ENOG4105CJW	magnesium transporter
BM449_07125	ENOG4107KCI	Protein CrcB homolog
BM449_07130	ENOG41086BQ	Protein CrcB homolog
BM449_07145	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BM449_07150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BM449_07155	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
BM449_07160	ENOG4105D7W	serine acetyltransferase
BM449_07165	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BM449_07180	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
BM449_07190	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM449_07200	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM449_07225	ENOG4105EY8	ABC transporter
BM449_07230	ENOG4105MFV	ABC-2 type transporter
BM449_07250	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BM449_07255	ENOG4106YF5	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
BM449_07295	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BM449_07310	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BM449_07325	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BM449_07330	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BM449_07335	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BM449_07340	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BM449_07345	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BM449_07355	ENOG4105C6E	dna polymerase iii
BM449_07365	ENOG4105JFG	SpoIID LytB domain protein
BM449_07370	ENOG41084A0	50s ribosomal protein L35
BM449_07375	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BM449_07390	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BM449_07400	ENOG4105CMR	udp-glucose 4-epimerase
BM449_07425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BM449_07430	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
BM449_07500	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BM449_07505	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BM449_07510	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BM449_07520	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BM449_07530	ENOG4105DFU	Cell wall formation (By similarity)
BM449_07535	ENOG4105D4A	Cell wall formation (By similarity)
BM449_07540	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BM449_07545	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BM449_07555	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BM449_07560	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM449_07570	ENOG4105CZX	twitching motility protein
BM449_07580	ENOG4105CBX	hi0933 family
BM449_07595	ENOG4105CH7	arginosuccinase
BM449_07600	ENOG4107SGM	protein serine threonine phosphatase
BM449_07610	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
BM449_07625	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BM449_07645	ENOG4105EXC	Acyl-transferase
BM449_07650	ENOG4108HMX	isocitrate dehydrogenase (NADP)
BM449_07670	ENOG4105BZ1	(ABC) transporter
BM449_07675	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BM449_07680	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BM449_07725	ENOG4107TYR	Glycosyl Transferase
BM449_07730	ENOG4105CPK	Glycosyl transferase (Group 1
BM449_07745	ENOG4107EF8	Glycosyl transferase (Group 1
BM449_07760	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BM449_07765	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BM449_07770	ENOG4105C2X	Arabinose 5-phosphate isomerase
BM449_07775	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BM449_07805	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BM449_07815	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BM449_07830	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BM449_07840	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BM449_07845	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
BM449_07850	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BM449_07855	ENOG4105C37	(CBS) domain
BM449_07870	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
BM449_07875	ENOG4106815	This protein is a component of the reaction center of photosystem II (By similarity)
BM449_07880	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BM449_07885	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
BM449_07905	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BM449_07920	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BM449_07930	ENOG4105PW4	Sugar fermentation stimulation protein homolog
BM449_07960	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BM449_07965	ENOG4105ESV	Glycosyl transferase, family 4
BM449_07970	ENOG4105CEV	competence damage-inducible protein
BM449_07975	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BM449_07995	ENOG4107M19	This protein is a component of the reaction center of photosystem II (By similarity)
BM449_08005	ENOG41087M8	photosystem II reaction center protein N
BM449_08010	ENOG4105WIA	photosystem II reaction center protein H
BM449_08020	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BM449_08035	ENOG4108R0D	protein with myosin-like
BM449_08040	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
BM449_08045	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BM449_08050	ENOG4105DHP	deoxycytidine triphosphate deaminase
BM449_08075	ENOG4105E4C	Lytic transglycosylase catalytic
BM449_08085	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BM449_08100	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BM449_08125	ENOG4105DVC	DnaJ domain protein
BM449_08130	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BM449_08160	ENOG4105CVK	Glutamate decarboxylase
BM449_08195	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BM449_08205	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM449_08210	ENOG4105EB3	Histidine kinase
BM449_08220	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BM449_08235	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BM449_08245	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BM449_08255	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BM449_08260	ENOG4107W9I	Creatinine amidohydrolase
BM449_08270	ENOG4105CXT	aspartate transcarbamylase
BM449_08305	ENOG4105CPJ	photosystem II manganese-stabilizing
BM449_08340	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BM449_08345	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
BM449_08350	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BM449_08360	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BM449_08365	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
BM449_08375	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM449_08395	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BM449_08400	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BM449_08405	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BM449_08410	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BM449_08415	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BM449_08440	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BM449_08450	ENOG4105E4R	Precorrin-3B C17-methyltransferase
BM449_08460	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
BM449_08465	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
BM449_08475	ENOG4108W6I	photosystem I reaction center protein subunit XI
BM449_08490	ENOG4105CKK	Glycosyl transferase, family 2
BM449_08510	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BM449_08520	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BM449_08525	ENOG41082HT	Binds the 23S rRNA (By similarity)
BM449_08530	ENOG4108UJD	30S ribosomal protein S9
BM449_08540	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BM449_08550	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM449_08560	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BM449_08565	ENOG41067V7	50S ribosomal protein L36
BM449_08570	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BM449_08575	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BM449_08580	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BM449_08585	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BM449_08595	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BM449_08605	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BM449_08610	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BM449_08615	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BM449_08620	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BM449_08625	ENOG410848H	50s ribosomal protein l29
BM449_08630	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BM449_08635	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BM449_08640	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BM449_08645	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BM449_08650	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BM449_08655	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BM449_08660	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BM449_08665	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BM449_08670	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BM449_08680	ENOG4105CD2	stage iii sporulation protein aa
BM449_08695	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BM449_08745	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
BM449_08755	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BM449_08760	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BM449_08775	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BM449_08780	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
BM449_08800	ENOG4105CNI	cell division protein FtsW
BM449_08810	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BM449_08860	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BM449_08870	ENOG4105CAT	Cytidine monophosphate kinase
BM449_08880	ENOG4108V9J	phycocyanobilin lyase
BM449_08895	ENOG4105D6V	phycocyanin beta subunit
BM449_08920	ENOG4108REV	C-phycoerythrin class I alpha chain
BM449_08960	ENOG4108REV	C-phycoerythrin class I alpha chain
BM449_08985	ENOG4108KKY	Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin (By similarity)
BM449_08995	ENOG4106BTU	phycobilisome rod-core linker polypeptide
BM449_09025	ENOG4107S5T	Carbohydrate kinase
BM449_09030	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BM449_09035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BM449_09040	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BM449_09055	ENOG4105YVZ	photosystem II
BM449_09065	ENOG41069TS	Photosystem II reaction center protein M
BM449_09070	ENOG4108U51	Universal stress protein
BM449_09085	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BM449_09090	ENOG4107XQ8	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BM449_09120	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BM449_09125	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BM449_09140	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BM449_09150	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BM449_09155	ENOG4105DCI	Phosphohydrolase
BM449_09160	ENOG4105CN1	protease
BM449_09165	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BM449_09170	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
BM449_09225	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BM449_09235	ENOG4105CQ7	ATP-dependent helicase
BM449_09250	ENOG4105C0H	protease
BM449_09260	ENOG4105C5H	ABC transporter
BM449_09275	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BM449_09285	ENOG4105D3R	alkyl hydroperoxide reductase
BM449_09295	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BM449_09300	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
BM449_09310	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BM449_09315	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BM449_09320	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM449_09345	ENOG4105BZS	acriflavin resistance protein
BM449_09365	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
BM449_09405	ENOG4106BTU	phycobilisome rod-core linker polypeptide
BM449_09410	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
BM449_09470	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BM449_09490	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BM449_09505	ENOG410848W	30S ribosomal protein S21
BM449_09510	ENOG4105C0P	Mg chelatase subunit ChlI
BM449_09515	ENOG4107YU2	histidine triad (hIT) protein
BM449_09535	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
BM449_09545	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BM449_09560	ENOG4105E0X	reductase
BM449_09570	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BM449_09610	ENOG4105CVB	Vitamin K epoxide reductase
BM449_09620	ENOG4105D52	delta-aminolevulinic acid dehydratase
BM449_09635	ENOG4108IJ9	(ABC) transporter
BM449_09640	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BM449_09650	ENOG4105C5H	ABC transporter
BM449_09660	ENOG4105CHF	Glutathione S-transferase
BM449_09665	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
BM449_09680	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
BM449_09685	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BM449_09720	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BM449_09730	ENOG4105CHV	Transcription elongation factor NusA
BM449_09735	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
BM449_09745	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
BM449_09750	ENOG4105C0H	protease
BM449_09755	ENOG4105E66	phosphoriboisomerase A
BM449_09760	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BM449_09765	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
BM449_09775	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM449_09780	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM449_09785	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM449_09795	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BM449_09805	ENOG4105EYM	Major Facilitator superfamily
BM449_09825	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
BM449_09835	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BM449_09840	ENOG4108P61	DnaJ domain protein
BM449_09850	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BM449_09855	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BM449_09875	ENOG4105CQR	helicase
BM449_09880	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
BM449_09905	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BM449_09915	ENOG4105VFU	Rna-binding protein
BM449_09920	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BM449_09935	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BM449_09955	ENOG4108IQE	Amp-dependent synthetase and ligase
BM449_09960	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BM449_09985	ENOG4108KMV	Glycosyl transferase (Group 1
BM449_10000	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BM449_10010	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BM449_10015	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BM449_10035	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BM449_10050	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BM449_10065	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BM449_10070	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM449_10090	ENOG4105C12	Phosphoribosylglycinamide synthetase
BM449_10100	ENOG4105EHU	Circadian clock protein KaiC
BM449_10110	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
BM449_10115	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BM449_10125	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BM449_10135	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BM449_10140	ENOG4105CDY	transcriptional regulatory protein
BM449_10145	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BM449_10150	ENOG4105JFG	SpoIID LytB domain protein
BM449_10155	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BM449_10160	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
BM449_10175	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BM449_10190	ENOG4105DBK	s4 domain protein
BM449_10200	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BM449_10225	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BM449_10230	ENOG4105CFG	Acts as a chaperone (By similarity)
BM449_10245	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BM449_10250	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BM449_10260	ENOG4105E0X	reductase
BM449_10265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BM449_10270	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BM449_10275	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BM449_10280	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BM449_10285	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
BM449_10295	ENOG4107RAQ	aminopeptidase
BM449_10305	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BM449_10320	ENOG4105DCF	alanine dehydrogenase
BM449_10345	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BM449_10350	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BM449_10355	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM449_10360	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM449_10365	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM449_10375	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
BM449_10385	ENOG4107SWE	Methyltransferase
BM449_10420	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
BM449_10425	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BM449_10440	ENOG4108YZA	Nitrogen regulatory protein pii
BM449_10520	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
BM449_10525	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM449_10535	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM449_10540	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BM449_10545	ENOG4105D7N	magnesium and cobalt transport protein CorA
BM449_10560	ENOG4108HQR	Glycine betaine
BM449_10585	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BM449_10595	ENOG4105BZ1	(ABC) transporter
BM449_10605	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BM449_10610	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BM449_10615	ENOG41082AN	stage II sporulation protein
BM449_10635	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BM449_10640	ENOG4105RQ9	TPR repeat-containing protein
BM449_10675	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BM449_10680	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BM449_10690	ENOG4105D0S	secretion protein (HlyD
BM449_10695	ENOG4105CJ1	ABC, transporter
BM449_10700	ENOG4105CMI	transporter
BM449_10740	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BM449_10750	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BM449_10755	ENOG4105KT5	UmuD protein
BM449_10775	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BM449_10785	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BM449_10800	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM449_10805	ENOG4107TV7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM449_10820	ENOG4105DSF	transport protein
BM449_10825	ENOG4105MSA	Photosystem II reaction center W protein
BM449_10830	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
BM449_10855	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BM449_10860	ENOG4105C5F	glutamine synthetase
BM449_10865	ENOG4108TCG	allophycocyanin beta subunit
BM449_10870	ENOG4105C5R	Aminotransferase
BM449_10890	ENOG4105BZ4	penicillin-binding protein
BM449_10895	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BM449_10915	ENOG4105C1V	Peptidase, M16
BM449_10925	ENOG4105D0S	secretion protein (HlyD
BM449_10935	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BM449_10940	ENOG4107R51	Glycosyl transferase, family 2
BM449_10945	ENOG4105CE9	30S ribosomal protein S2
BM449_10950	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BM449_10980	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BM449_11010	ENOG4108IUZ	ABC transporter
BM449_11020	ENOG4105CRE	cytochrome C
BM449_11030	ENOG4105CBT	Fructose-1,6-bisphosphatase
BM449_11035	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BM449_11040	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BM449_11045	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BM449_11065	ENOG4105C01	Dihydroxy-acid dehydratase
BM449_11110	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM449_11120	ENOG4108VPT	UPF0234 protein
BM449_11165	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BM449_11190	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BM449_11230	ENOG4107YJ4	chain length determinant protein
BM449_11260	ENOG4105ESV	Glycosyl transferase, family 4
BM449_11305	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM449_11310	ENOG4107T8Q	Glycosyl transferase (Group 1
BM449_11315	ENOG4106WTF	Glycosyl transferase, family 2
BM449_11325	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM449_11345	ENOG4105E2K	Glycosyl transferase (Group 1
BM449_11370	ENOG4108SHN	Glycosyl transferase, family 2
BM449_11410	ENOG4105CPK	Glycosyl transferase (Group 1
BM449_11420	ENOG4108SHN	Glycosyl transferase, family 2
BM449_11475	ENOG4105BZ1	(ABC) transporter
BM449_11570	ENOG4105C8N	cysteinyl-tRNA synthetase
BM449_11580	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BM449_11585	ENOG4105NZG	Ferredoxin
BM449_11610	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BM449_11615	ENOG4108R99	pseudouridine synthase
BM449_11640	ENOG4108MUZ	hydrolase
BM449_11655	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
BM449_11680	ENOG4108Z03	MAF-like protein
BM449_11700	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BM449_11710	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_11715	ENOG4108JYK	Dehydrogenase
BM449_11740	ENOG4105HFZ	Membrane
BM449_11745	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
BM449_11750	ENOG4105C30	Nad-dependent epimerase dehydratase
BM449_11770	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BM449_11775	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BM449_11785	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
BM449_11815	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BM449_11820	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BM449_11825	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BM449_11865	ENOG4105D64	Mechanosensitive ion channel
BM449_11890	ENOG4105ECK	Fatty Acid Desaturase
BM449_11910	ENOG4105F9F	transposase
BM449_11940	ENOG4105DBV	ornithine carbamoyltransferase
BM449_11965	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
BM449_11970	ENOG4107QIZ	NADH dehydrogenase
BM449_11995	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
BM449_12050	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BM449_12060	ENOG4105CQS	hydrogenase expression formation protein HypD
BM449_12065	ENOG4105C45	hydrogenase expression formation protein (HypE)
BM449_12070	ENOG4105C6T	cysteine synthase
BM449_12075	ENOG4105FEU	K -dependent Na -Ca exchanger
BM449_12080	ENOG4105CHH	sulfate transporter
BM449_12095	ENOG4105D65	subunit l
BM449_12115	ENOG4108YZA	Nitrogen regulatory protein pii
BM449_12120	ENOG4105CDA	abc transporter atp-binding protein
BM449_12125	ENOG4105DRP	amino acid AbC transporter
BM449_12130	ENOG4105EZ7	amino acid ABC transporter
BM449_12135	ENOG4107QXX	ABC transporter
BM449_12140	ENOG4105CZN	Potassium uptake protein
BM449_12145	ENOG4105EKE	dihydroorotase
BM449_12170	ENOG41080Y1	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
BM449_12175	ENOG4107RSS	Hydrogenase accessory protein HypB
BM449_12185	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
BM449_12205	ENOG41066HZ	AIG2-like family
BM449_12245	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BM449_12250	ENOG4107QVI	Methyltransferase, type 11
BM449_12255	ENOG41065KQ	synthase
BM449_12290	ENOG4108RIN	C-phycoerythrin class I beta chain
BM449_12325	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BM449_12345	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
BM449_12370	ENOG4107S1E	Beta-lactamase
BM449_12375	ENOG4105D49	3-dehydroquinate synthase
BM449_12380	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BM449_12385	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BM449_12390	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BM449_12420	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
BM449_12425	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BM449_12445	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BM449_12475	ENOG4105C7B	Threonine dehydratase
BM449_12480	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BM449_12490	ENOG4105VGQ	Photosystem I subunit X
BM449_12510	ENOG41083EU	50s ribosomal protein l28
BM449_12515	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BM449_12520	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
BM449_12535	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
BM449_12555	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BM449_12560	ENOG4105E2Z	phosphate ABC transporter (Permease
BM449_12565	ENOG4105C8U	phosphate abc transporter
BM449_12575	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BM449_12585	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM449_12590	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
BM449_12595	ENOG4108ZCU	PPIases accelerate the folding of proteins
BM449_12605	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BM449_12610	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BM449_12635	ENOG4105C89	phosphohexose isomerase
BM449_12645	ENOG4105C4W	S-formylglutathione hydrolase
BM449_12650	ENOG4105C8T	Leucyl-tRNA synthetase
BM449_12660	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BM449_12665	ENOG4105C3J	Cysteine desulfurase
BM449_12690	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BM449_12700	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BM449_12720	ENOG4105CTK	cobaltochelatase, cobn subunit
BM449_12755	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BM449_12760	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
BM449_12765	ENOG4105JFG	SpoIID LytB domain protein
BM449_12775	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_12790	ENOG4105C9X	ppx gppa phosphatase
BM449_12805	ENOG4105CMM	transposase
BM449_12815	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BM449_12820	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BM449_12825	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BM449_12860	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
BM449_12875	ENOG4108K5P	(LipO)protein
BM449_12900	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
BM449_12915	ENOG4107QRP	cobalamin biosynthesis protein CobW
BM449_12925	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BM449_12930	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BM449_12935	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BM449_12950	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BM449_12955	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
BM449_12960	ENOG4108IPT	Naphthoate synthase
BM449_12965	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
BM449_12985	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
BM449_12995	ENOG4105PGM	cation diffusion facilitator family transporter
BM449_13010	ENOG4105C31	Tryptophanyl-tRNA synthetase
BM449_13025	ENOG4105C22	threonyL-tRNA synthetase
BM449_13030	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BM449_13035	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BM449_13040	ENOG4105C8S	subunit m
BM449_13045	ENOG4105DGW	oligopeptidase A
BM449_13060	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BM449_13065	ENOG4105DKQ	ROK family
BM449_13100	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BM449_13105	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BM449_13115	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
BM449_13120	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
BM449_13145	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BM449_13165	ENOG4105EYW	Ion transport protein
BM449_13180	ENOG41069EW	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
BM449_13190	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BM449_13200	ENOG4105DQ4	alcohol dehydrogenase
BM449_13215	ENOG4105TQG	cytochrome C, class I
BM449_13255	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_13270	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BM449_13280	ENOG4108PJD	permease
BM449_13305	ENOG4105FDK	ABC transporter
BM449_13310	ENOG4105DSE	periplasmic solute binding protein
BM449_13320	ENOG4107E2E	PKHD-type hydroxylase
BM449_13325	ENOG4108PWY	Carbohydrate-selective porin OprB
BM449_13330	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BM449_13335	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BM449_13345	ENOG4108JJB	ABC transporter
BM449_13355	ENOG4105CKI	cobalamin synthesis protein
BM449_13370	ENOG4108HQS	Glycine betaine
BM449_13380	ENOG4108KQ5	Integrase catalytic subunit
BM449_13405	ENOG4107XWZ	ferric uptake regulator
BM449_13415	ENOG4105C8M	UPF0272 protein
BM449_13440	ENOG4105CGK	Exodeoxyribonuclease III
BM449_13445	ENOG4105CQB	FAD linked oxidase domain protein
BM449_13450	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BM449_13465	ENOG4108N5B	2-phosphosulfolactate phosphatase
BM449_13475	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BM449_13480	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BM449_13495	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BM449_13535	ENOG4105CTD	carboxy-peptidase
BM449_13540	ENOG4105F0N	pyrophosphate phospho-hydrolase
BM449_13545	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
BM449_13555	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BM449_13570	ENOG4107SH3	glycosyl transferase, family 39
BM449_13575	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM449_13590	ENOG4105CAS	nag kinase
BM449_13620	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BM449_13625	ENOG4105J0U	photosystem II
BM449_13630	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BM449_13660	ENOG4105CVJ	phosphoglycerate mutase
BM449_13680	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BM449_13690	ENOG4105P52	geranylgeranyl reductase
BM449_13695	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BM449_13705	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BM449_13715	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BM449_13720	ENOG4105C7K	acetolactate synthase
BM449_13740	ENOG4105DZ0	fad dependent oxidoreductase
BM449_13750	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BM449_13760	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BM449_13770	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
BM449_13775	ENOG4105E6N	shikimate quinate 5-dehydrogenase
BM449_13780	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BM449_13785	ENOG4105EMU	Dehydrogenase
BM449_13790	ENOG4105EUJ	GTP cyclohydrolase i
BM449_13810	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
BM449_13850	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
BM449_13855	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
BM449_13860	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
BM449_13865	ENOG4105KNY	Microcompartments protein
BM449_13870	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
BM449_13875	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
BM449_13900	ENOG4105KNY	Microcompartments protein
BM449_13915	ENOG4106F1P	AAA ATPase, central domain protein