locus-tag	class	description
M744_00005	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
M744_00010	ENOG4105C0H	protease
M744_00020	ENOG4105EET	magnesium chelatase
M744_00055	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
M744_00095	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_00100	ENOG4107TTD	cytosine deaminase
M744_00105	ENOG4105EU8	FAD linked oxidase domain protein
M744_00120	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
M744_00125	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
M744_00140	ENOG4108JJB	ABC transporter
M744_00145	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
M744_00160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
M744_00170	ENOG4105C3G	gtp-binding protein
M744_00175	ENOG4105D0S	secretion protein (HlyD
M744_00180	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
M744_00200	ENOG4107TS3	membrane protein, TerC
M744_00230	ENOG4108YYH	Nadph-dependent fmn reductase
M744_00235	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
M744_00260	ENOG4105CV1	Transketolase (EC 2.2.1.1)
M744_00270	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
M744_00275	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
M744_00280	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
M744_00305	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
M744_00375	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
M744_00380	ENOG4105CN1	protease
M744_00395	ENOG4108IUZ	ABC transporter
M744_00405	ENOG4105CRE	cytochrome C
M744_00420	ENOG4105P52	geranylgeranyl reductase
M744_00425	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
M744_00430	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
M744_00435	ENOG4105CBT	Fructose-1,6-bisphosphatase
M744_00440	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
M744_00450	ENOG4108YYQ	gCN5-related N-acetyltransferase
M744_00495	ENOG4105CSR	polyphosphate kinase 2
M744_00510	ENOG4105BZU	Histidine kinase
M744_00515	ENOG4105C26	Dehydrogenase
M744_00535	ENOG4105CVJ	phosphoglycerate mutase
M744_00550	ENOG4105CJN	penicillin-binding protein
M744_00560	ENOG4105BZU	Histidine kinase
M744_00565	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
M744_00575	ENOG41067XK	integral membrane protein
M744_00595	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
M744_00600	ENOG41060D5	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
M744_00605	ENOG4105DRS	transport system, permease
M744_00620	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
M744_00635	ENOG4107QZ7	Cellulose synthase catalytic subunit
M744_00645	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
M744_00665	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
M744_00675	ENOG4105C4W	S-formylglutathione hydrolase
M744_00685	ENOG4107DVA	This protein is a component of the reaction center of photosystem II (By similarity)
M744_00690	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
M744_00695	ENOG4107Z12	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
M744_00700	ENOG41062D9	Histidine kinase
M744_00715	ENOG41083MR	nifu domain-containing protein
M744_00720	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
M744_00725	ENOG4105DZP	Membrane-associated zinc metalloprotease
M744_00740	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
M744_00750	ENOG4108SHJ	s-layer protein
M744_00765	ENOG4105CE4	GlcNAc 6-P deacetylase
M744_00795	ENOG4108PJD	permease
M744_00820	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
M744_00835	ENOG4105CJ1	ABC, transporter
M744_00850	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
M744_00875	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
M744_00920	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
M744_00935	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
M744_00970	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
M744_00980	ENOG4105DDQ	anthranilate synthase
M744_01000	ENOG4105DC1	bifunctional purine biosynthesis protein purh
M744_01020	ENOG4105CA3	membrane-bound lytic murein transglycosylase
M744_01045	ENOG4105K8N	protein family UPF0079, ATPase
M744_01050	ENOG4105CHW	UPF0052 protein
M744_01120	ENOG4105N1N	Cupin superfamily protein
M744_01130	ENOG4105CVG	Homoserine O-transsuccinylase
M744_01145	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
M744_01155	ENOG4105C09	Bile acid
M744_01175	ENOG4108Y85	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
M744_01205	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
M744_01210	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
M744_01235	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
M744_01240	ENOG4105D17	glycoside hydrolase, family 3 domain protein
M744_01245	ENOG4105C09	Bile acid
M744_01250	ENOG4105E0X	reductase
M744_01260	ENOG4105DHJ	ABC, transporter
M744_01270	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
M744_01285	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
M744_01295	ENOG4105J0U	photosystem II
M744_01330	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
M744_01335	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
M744_01340	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
M744_01345	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
M744_01350	ENOG4105S30	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
M744_01355	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
M744_01360	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
M744_01370	ENOG4107SWE	Methyltransferase
M744_01375	ENOG4105EEK	Polypeptide
M744_01400	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
M744_01405	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
M744_01410	ENOG4108YZA	Nitrogen regulatory protein pii
M744_01420	ENOG4105DX0	Hemolysin A
M744_01455	ENOG41083KH	UPF0102 protein
M744_01460	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
M744_01465	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
M744_01470	ENOG4105D65	subunit l
M744_01505	ENOG4105N82	Endonuclease
M744_01510	ENOG41080E3	single-stranded DNA-binding protein
M744_01515	ENOG4105DFF	Rod shape-determining protein mreb
M744_01520	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
M744_01540	ENOG4107RIQ	Sulfate adenylate transferase
M744_01545	ENOG4105CPJ	photosystem II manganese-stabilizing
M744_01570	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
M744_01575	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
M744_01580	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
M744_01585	ENOG4105EYW	Ion transport protein
M744_01610	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
M744_01615	ENOG4105ESV	Glycosyl transferase, family 4
M744_01620	ENOG4105CEV	competence damage-inducible protein
M744_01625	ENOG4107QIZ	NADH dehydrogenase
M744_01630	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
M744_01635	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
M744_01640	ENOG4105CQB	FAD linked oxidase domain protein
M744_01645	ENOG4105VXP	Protein of unknown function DUF86
M744_01655	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
M744_01660	ENOG4108DIF	synthase (EC 4.2.1.75)
M744_01665	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
M744_01670	ENOG4107TVC	Glycosyl transferase, family 2
M744_01685	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
M744_01695	ENOG4105DVC	DnaJ domain protein
M744_01710	ENOG4105C8B	TIGR00159 family
M744_01720	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
M744_01780	ENOG4105CDA	abc transporter atp-binding protein
M744_01785	ENOG4105DRP	amino acid AbC transporter
M744_01790	ENOG4105EZ7	amino acid ABC transporter
M744_01795	ENOG4107QXX	ABC transporter
M744_01800	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
M744_01810	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
M744_01825	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
M744_01840	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
M744_01855	ENOG4105IJJ	transcriptional regulator, crp fnr family
M744_01875	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
M744_01900	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
M744_01905	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
M744_01910	ENOG4105WIA	photosystem II reaction center protein H
M744_01915	ENOG410686T	photosystem II reaction center protein N
M744_01930	ENOG4105CHC	glucokinase (EC 2.7.1.2)
M744_01945	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
M744_01960	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
M744_01990	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
M744_02000	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
M744_02010	ENOG4108Z03	MAF-like protein
M744_02045	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
M744_02105	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
M744_02110	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
M744_02115	ENOG4105BZU	Histidine kinase
M744_02135	ENOG4105CJ3	phosphate transporter
M744_02160	ENOG4108Z7R	Chaperone CsaA
M744_02190	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
M744_02255	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
M744_02260	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
M744_02280	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
M744_02300	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
M744_02305	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
M744_02310	ENOG4105CKK	Glycosyl transferase, family 2
M744_02315	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
M744_02360	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
M744_02370	ENOG4105C7K	acetolactate synthase
M744_02380	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
M744_02425	ENOG4108R0D	protein with myosin-like
M744_02430	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
M744_02435	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
M744_02440	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
M744_02445	ENOG4105FQ6	thiopurine methyltransferase
M744_02460	ENOG4108M8H	domain protein
M744_02475	ENOG4108Z6B	deaminase
M744_02485	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
M744_02495	ENOG4105D7K	pfkb domain protein
M744_02515	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
M744_02520	ENOG4105CFG	Acts as a chaperone (By similarity)
M744_02540	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
M744_02590	ENOG4105CTK	cobaltochelatase, cobn subunit
M744_02605	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
M744_02610	ENOG4105C6E	dna polymerase iii
M744_02615	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
M744_02630	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
M744_02680	ENOG4105BZ1	(ABC) transporter
M744_02685	ENOG4105WQ3	Rna-binding protein
M744_02690	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
M744_02710	ENOG4106PMH	Extracellular solute-binding protein family 3
M744_02715	ENOG4107RAQ	aminopeptidase
M744_02730	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
M744_02755	ENOG4105CJ1	ABC, transporter
M744_02770	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
M744_02790	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
M744_02795	ENOG4105FAW	cDP-glucose 4,6-dehydratase
M744_02820	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
M744_02850	ENOG4105K64	Glycosyl transferase, family 2
M744_02855	ENOG4105KHS	type IV fimbrial pilin protein
M744_02860	ENOG4105KHS	type IV fimbrial pilin protein
M744_02870	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
M744_02890	ENOG41083EU	50s ribosomal protein l28
M744_02905	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
M744_02910	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
M744_02935	ENOG4105VXP	Protein of unknown function DUF86
M744_02940	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
M744_02945	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
M744_02950	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
M744_02960	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
M744_03000	ENOG4107QHM	Sulfite reductase
M744_03005	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
M744_03010	ENOG4108UHU	Aldolase
M744_03025	ENOG4107E2E	PKHD-type hydroxylase
M744_03045	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
M744_03060	ENOG4105CDH	Citrulline--aspartate ligase
M744_03085	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
M744_03090	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
M744_03100	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
M744_03105	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
M744_03140	ENOG4105C22	threonyL-tRNA synthetase
M744_03165	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
M744_03170	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
M744_03185	ENOG41080ZE	Adenylate cyclase
M744_03190	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
M744_03195	ENOG4105C37	(CBS) domain
M744_03215	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
M744_03230	ENOG4108N5B	2-phosphosulfolactate phosphatase
M744_03255	ENOG4105CHR	reductase
M744_03270	ENOG410811Q	Ferredoxin
M744_03280	ENOG4108KBA	Acts as a chaperone (By similarity)
M744_03285	ENOG4105DVC	DnaJ domain protein
M744_03295	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
M744_03330	ENOG4105DSE	periplasmic solute binding protein
M744_03335	ENOG4105DIK	(ABC) transporter
M744_03340	ENOG4105CC5	ABC transporter
M744_03350	ENOG4108JQC	penicillin-binding protein 1A
M744_03355	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
M744_03360	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
M744_03370	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
M744_03380	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
M744_03385	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
M744_03390	ENOG4105EYH	Exonuclease
M744_03395	ENOG4105CXI	aluminum resistance protein
M744_03410	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
M744_03415	ENOG4105C3J	Cysteine desulfurase
M744_03440	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
M744_03470	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
M744_03495	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
M744_03500	ENOG4105TQG	cytochrome C, class I
M744_03515	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
M744_03530	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
M744_03540	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
M744_03545	ENOG4105BZU	Histidine kinase
M744_03565	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
M744_03570	ENOG4105CE9	30S ribosomal protein S2
M744_03585	ENOG4107S9D	Alpha beta hydrolase
M744_03590	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
M744_03595	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
M744_03600	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
M744_03610	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
M744_03615	ENOG4108IAB	Phoh family
M744_03620	ENOG4108URH	decarboxylase
M744_03625	ENOG4105BZU	Histidine kinase
M744_03630	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
M744_03655	ENOG4107QKA	exodeoxyribonuclease V beta
M744_03660	ENOG4105DBV	ornithine carbamoyltransferase
M744_03675	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
M744_03685	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
M744_03705	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
M744_03730	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
M744_03740	ENOG4105DZ6	Band 7 protein
M744_03750	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
M744_03760	ENOG4105C32	Amino acid ABC transporter (Permease)
M744_03765	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
M744_03770	ENOG4105C0Z	ABC transporter
M744_03775	ENOG4108IV0	ABC, transporter
M744_03790	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
M744_03805	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
M744_03830	ENOG4105MSA	Photosystem II reaction center W protein
M744_03845	ENOG4105CH7	arginosuccinase
M744_03855	ENOG4107SGM	protein serine threonine phosphatase
M744_03865	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
M744_03880	ENOG4105CFG	Acts as a chaperone (By similarity)
M744_03885	ENOG4105E2X	shikimate dehydrogenase
M744_03890	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
M744_03905	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
M744_03910	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
M744_03915	ENOG4107S5T	Carbohydrate kinase
M744_03945	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
M744_03990	ENOG4105GVR	general secretion pathway protein D
M744_03995	ENOG4105D3R	alkyl hydroperoxide reductase
M744_04000	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
M744_04015	ENOG4105PWN	phosphate abc transporter
M744_04020	ENOG4105PWN	phosphate abc transporter
M744_04025	ENOG4105C8U	phosphate abc transporter
M744_04030	ENOG4105E2Z	phosphate ABC transporter (Permease
M744_04035	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
M744_04040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
M744_04060	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
M744_04065	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
M744_04080	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
M744_04110	ENOG4105KHC	sulfurtransferase
M744_04130	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
M744_04145	ENOG4105D7W	serine acetyltransferase
M744_04155	ENOG41080UQ	Transcriptional regulator
M744_04170	ENOG4105CRK	lysyL-tRNA synthetase
M744_04180	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
M744_04185	ENOG4107QX8	SPFH domain, Band 7 family protein
M744_04190	ENOG4105KWG	Pfam:DUF1696
M744_04200	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
M744_04220	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
M744_04250	ENOG4105DWY	Agmatine deiminase
M744_04255	ENOG4105VN1	Heat shock protein
M744_04270	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
M744_04295	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
M744_04320	ENOG4105F0F	Oxalate decarboxylase
M744_04330	ENOG4105CQS	hydrogenase expression formation protein HypD
M744_04335	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
M744_04355	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
M744_04365	ENOG4105DWF	phosphomethylpyrimidine kinase
M744_04370	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
M744_04385	ENOG4105CPF	Cell wall formation (By similarity)
M744_04390	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
M744_04395	ENOG4105DTQ	mandelate racemase muconate lactonizing
M744_04405	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
M744_04440	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
M744_04460	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
M744_04465	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
M744_04500	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
M744_04510	ENOG4105C8M	UPF0272 protein
M744_04515	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
M744_04520	ENOG4105CZX	twitching motility protein
M744_04525	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
M744_04540	ENOG4105KAN	Probably a ribosomal protein or a ribosome-associated protein (By similarity)
M744_04555	ENOG41068FK	Photosystem I reaction center subunit VIII
M744_04560	ENOG4108W6I	photosystem I reaction center protein subunit XI
M744_04565	ENOG4107U45	Cobalt transport protein
M744_04570	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
M744_04575	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
M744_04600	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
M744_04605	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
M744_04610	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
M744_04615	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
M744_04625	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
M744_04635	ENOG4105DCI	Phosphohydrolase
M744_04660	ENOG4105D7Z	glutathione synthase
M744_04675	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
M744_04680	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
M744_04695	ENOG41082AG	Plasmid maintenance system antidote protein
M744_04700	ENOG4108ZFD	Antibiotic biosynthesis monooxygenase
M744_04705	ENOG4105C59	p-type ATPase
M744_04710	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
M744_04715	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
M744_04720	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
M744_04725	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
M744_04730	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
M744_04750	ENOG4105DY8	decarboxylase
M744_04760	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
M744_04770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
M744_04775	ENOG4105ETX	regulatoR
M744_04780	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
M744_04805	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
M744_04810	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
M744_04815	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
M744_04845	ENOG4105C2X	Arabinose 5-phosphate isomerase
M744_04850	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
M744_04855	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
M744_04860	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
M744_04880	ENOG4108MUZ	hydrolase
M744_04885	ENOG4108UQV	Membrane
M744_04890	ENOG4105BZU	Histidine kinase
M744_04905	ENOG4105BZU	Histidine kinase
M744_04945	ENOG4105EET	magnesium chelatase
M744_04975	ENOG4108K7V	UPF0284 protein
M744_04990	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
M744_05000	ENOG4105CUT	histidyl-tRNA synthetase
M744_05025	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
M744_05030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
M744_05055	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
M744_05060	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
M744_05075	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
M744_05085	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
M744_05100	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
M744_05110	ENOG4106YF5	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna (By similarity)
M744_05115	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
M744_05135	ENOG4107WJM	-acetyltransferase
M744_05150	ENOG41079KZ	Major Facilitator Superfamily
M744_05160	ENOG4108JQ6	ABC transporter
M744_05165	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
M744_05170	ENOG4108USA	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
M744_05180	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
M744_05185	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
M744_05190	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
M744_05195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
M744_05200	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
M744_05205	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
M744_05210	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
M744_05215	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
M744_05220	ENOG410848H	50s ribosomal protein l29
M744_05225	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
M744_05230	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
M744_05235	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
M744_05240	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
M744_05245	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
M744_05250	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
M744_05255	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
M744_05260	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
M744_05265	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
M744_05270	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
M744_05275	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
M744_05285	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
M744_05290	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
M744_05295	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
M744_05300	ENOG4108ZT0	50S ribosomal protein l17
M744_05305	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
M744_05310	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
M744_05315	ENOG4108UJD	30S ribosomal protein S9
M744_05320	ENOG41082HT	Binds the 23S rRNA (By similarity)
M744_05325	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
M744_05335	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
M744_05360	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
M744_05370	ENOG4105F8J	Adenylate Guanylate cyclase
M744_05380	ENOG4108ESY	Metal dependent phosphohydrolase
M744_05385	ENOG4105BZU	Histidine kinase
M744_05395	ENOG4105E0X	reductase
M744_05405	ENOG4105E4F	Isochorismate synthase
M744_05425	ENOG4105E7A	Glutamine amidotransferase
M744_05430	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
M744_05445	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M744_05455	ENOG41082T9	Membrane
M744_05470	ENOG4107QKW	extracellular solute-binding protein family 1
M744_05475	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
M744_05500	ENOG4107XWZ	ferric uptake regulator
M744_05555	ENOG4105C5R	Aminotransferase
M744_05560	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
M744_05565	ENOG4108TCG	allophycocyanin beta subunit
M744_05575	ENOG4105C5F	glutamine synthetase
M744_05600	ENOG4107QZ7	Cellulose synthase catalytic subunit
M744_05645	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
M744_05665	ENOG4108TGY	Glutathione S-transferase
M744_05685	ENOG4105CTK	cobaltochelatase, cobn subunit
M744_05690	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
M744_05700	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
M744_05710	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
M744_05735	ENOG4108S64	thioredoxin-like protein txlA
M744_05745	ENOG4105ZDA	
M744_05760	ENOG4108I0Q	anthranilate phosphoribosyltransferase
M744_05765	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
M744_05775	ENOG4108420	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M744_05790	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
M744_05810	ENOG4105BZU	Histidine kinase
M744_05815	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
M744_05825	ENOG4105DKQ	ROK family
M744_05830	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
M744_05835	ENOG4105BZ1	(ABC) transporter
M744_05845	ENOG4105I5W	Transporter
M744_05855	ENOG4105D7T	ABC transporter
M744_05860	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
M744_05875	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
M744_05880	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
M744_05885	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
M744_05890	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
M744_05910	ENOG410906A	Beta-Ig-H3 fasciclin
M744_05920	ENOG4105C8S	subunit m
M744_05935	ENOG4105CVB	Vitamin K epoxide reductase
M744_05950	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
M744_05965	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
M744_05970	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
M744_05990	ENOG4107QRI	Phosphoketolase
M744_05995	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
M744_06010	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
M744_06020	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
M744_06025	ENOG4105CFG	Acts as a chaperone (By similarity)
M744_06030	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
M744_06035	ENOG4107QHF	type ii secretion system protein e
M744_06040	ENOG4105CZX	twitching motility protein
M744_06055	ENOG4105CBX	hi0933 family
M744_06070	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
M744_06075	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
M744_06080	ENOG4108JT6	LycopEne
M744_06095	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
M744_06105	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
M744_06135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
M744_06150	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
M744_06155	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
M744_06160	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M744_06165	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
M744_06175	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
M744_06185	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
M744_06200	ENOG4105PW4	Sugar fermentation stimulation protein homolog
M744_06245	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
M744_06250	ENOG4106BTU	phycobilisome rod-core linker polypeptide
M744_06260	ENOG4105C89	phosphohexose isomerase
M744_06265	ENOG4105E2K	Glycosyl transferase (Group 1
M744_06270	ENOG4105K64	Glycosyl transferase, family 2
M744_06275	ENOG4105D3Q	Sugar transferase
M744_06290	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
M744_06295	ENOG4105CHV	Transcription elongation factor NusA
M744_06305	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
M744_06330	ENOG4106AG1	Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity)
M744_06355	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
M744_06360	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
M744_06365	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
M744_06370	ENOG4105CNW	domain protein
M744_06375	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
M744_06390	ENOG4105K6V	RNA polymerase
M744_06410	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
M744_06415	ENOG4108JQC	penicillin-binding protein 1A
M744_06420	ENOG4105VFU	Rna-binding protein
M744_06430	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
M744_06445	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
M744_06450	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
M744_06455	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
M744_06460	ENOG41084W5	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
M744_06470	ENOG4105PGM	cation diffusion facilitator family transporter
M744_06500	ENOG4105FE1	phytoene synthase
M744_06505	ENOG4105CVN	desaturase
M744_06510	ENOG4105GHY	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
M744_06520	ENOG4105DUM	transcriptional regulator, lysR family
M744_06530	ENOG4105K63	Thioredoxin
M744_06535	ENOG4105D65	subunit l
M744_06540	ENOG4105C8S	subunit m
M744_06585	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
M744_06595	ENOG4105C9X	ppx gppa phosphatase
M744_06610	ENOG4106CDA	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II (By similarity)
M744_06615	ENOG4108Z0R	Transferase
M744_06625	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
M744_06640	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
M744_06650	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
M744_06700	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
M744_06705	ENOG4108JYK	Dehydrogenase
M744_06715	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M744_06720	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
M744_06730	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
M744_06735	ENOG4105D6J	arsenicaL-resistance protein
M744_06770	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
M744_06780	ENOG4107QI6	Cysteine desulfurase
M744_06790	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
M744_06800	ENOG4105DR5	peptidase
M744_06810	ENOG4105EMN	RNA polymerase sigma factor
M744_06825	ENOG4105C8T	Leucyl-tRNA synthetase
M744_06900	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
M744_06905	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
M744_06935	ENOG4105DHP	deoxycytidine triphosphate deaminase
M744_06945	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
M744_06955	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
M744_06970	ENOG4105C0Z	ABC transporter
M744_06975	ENOG4105C72	UPF0176 protein
M744_06990	ENOG4107RFW	hydrolase family 57
M744_07005	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
M744_07010	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
M744_07015	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
M744_07025	ENOG41060KK	Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity)
M744_07030	ENOG4108IYU	L-aspartate oxidase
M744_07045	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
M744_07055	ENOG4105F8C	transglutaminase domain-containing protein
M744_07080	ENOG4105BZU	Histidine kinase
M744_07090	ENOG4105CW7	secretion protein, HlyD family
M744_07105	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
M744_07125	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
M744_07130	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
M744_07145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
M744_07165	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
M744_07170	ENOG4108Z6B	deaminase
M744_07175	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
M744_07185	ENOG4105DVK	Precorrin-2 c20-methyltransferase
M744_07190	ENOG41081F0	Precorrin-8x methylmutase
M744_07200	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
M744_07205	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_07225	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
M744_07240	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
M744_07280	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
M744_07305	ENOG4107QJE	Chromosome Partitioning Protein
M744_07310	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
M744_07315	ENOG4107QVP	Dehydrogenase
M744_07320	ENOG4105K63	Thioredoxin
M744_07325	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
M744_07345	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
M744_07350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
M744_07370	ENOG4105HFZ	Membrane
M744_07375	ENOG4105NAE	bifunctional deaminase-reductase domain protein
M744_07385	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
M744_07390	ENOG4105BZU	Histidine kinase
M744_07395	ENOG4108KXV	response regulator
M744_07400	ENOG4105EYW	Ion transport protein
M744_07415	ENOG4105BZU	Histidine kinase
M744_07420	ENOG4105CNW	domain protein
M744_07430	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
M744_07440	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M744_07465	ENOG4108YIQ	Alpha beta hydrolase
M744_07475	ENOG4105C45	hydrogenase expression formation protein (HypE)
M744_07500	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
M744_07505	ENOG4105CHM	Aminotransferase
M744_07510	ENOG4105N6Y	Thioredoxin
M744_07515	ENOG4105D52	delta-aminolevulinic acid dehydratase
M744_07525	ENOG4105DFE	Dna adenine methylase
M744_07560	ENOG4105DJZ	UPF0182 protein
M744_07580	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
M744_07610	ENOG4105VCC	30S ribosomal protein S21
M744_07620	ENOG41082B1	30S ribosomal protein S16
M744_07625	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M744_07645	ENOG4105C4M	(Ubiquinol oxidase) subunit I
M744_07665	ENOG4105ECY	inositol monophosphatase
M744_07670	ENOG4105XCI	PucC protein
M744_07680	ENOG4105DCF	alanine dehydrogenase
M744_07685	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
M744_07690	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
M744_07735	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
M744_07750	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_07760	ENOG4105WGP	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity)
M744_07765	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
M744_07775	ENOG4105DFU	Cell wall formation (By similarity)
M744_07780	ENOG4105D4A	Cell wall formation (By similarity)
M744_07785	ENOG4108Z6Z	Transcriptional regulator
M744_07825	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
M744_07850	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
M744_07855	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
M744_07870	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
M744_07895	ENOG4108HMX	isocitrate dehydrogenase (NADP)
M744_07900	ENOG4105EU8	FAD linked oxidase domain protein
M744_07905	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
M744_07910	ENOG4105BZU	Histidine kinase
M744_07915	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
M744_07920	ENOG4105DWV	Homoserine O-trans-acetylase
M744_07940	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
M744_07945	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
M744_07950	ENOG4105DGW	oligopeptidase A
M744_07975	ENOG4105C8I	hydrolase, family 38
M744_07990	ENOG4105C30	Nad-dependent epimerase dehydratase
M744_07995	ENOG4107QI1	Mate efflux family protein
M744_08000	ENOG4105KVH	Transcriptional regulator
M744_08030	ENOG4106H3A	restriction
M744_08040	ENOG4105KHC	sulfurtransferase
M744_08050	ENOG4108I5D	sulfate abc transporter
M744_08055	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
M744_08060	ENOG4105ECW	sulfate abc transporter
M744_08065	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
M744_08070	ENOG41060PK	NIL
M744_08075	ENOG4107Z6A	sulfate abc transporter permease
M744_08080	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
M744_08085	ENOG4108IJ6	ABC transporter
M744_08090	ENOG4105MSA	Photosystem II reaction center W protein
M744_08100	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
M744_08150	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
M744_08175	ENOG4105C8N	cysteinyl-tRNA synthetase
M744_08185	ENOG4105EYW	Ion transport protein
M744_08190	ENOG4108RCM	Nitroreductase
M744_08205	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
M744_08220	ENOG4105DCT	glycerol dehydrogenase
M744_08235	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
M744_08240	ENOG4105VCQ	rubredoxin
M744_08260	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
M744_08285	ENOG4105M0M	Tetracycline resistance protein
M744_08290	ENOG4108JJB	ABC transporter
M744_08295	ENOG4105VUV	UPF0367 protein
M744_08305	ENOG4105KZX	Pterin carbinolamine dehydratase
M744_08310	ENOG4108PWY	Carbohydrate-selective porin OprB
M744_08315	ENOG4108PWY	Carbohydrate-selective porin OprB
M744_08330	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
M744_08355	ENOG4108JPZ	Monovalent cation H antiporter subunit D
M744_08385	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
M744_08390	ENOG4106H78	methyltransferase
M744_08395	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
M744_08410	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
M744_08420	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
M744_08425	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
M744_08435	ENOG41089TF	bicarbonate transport system substrate-binding protein
M744_08440	ENOG4105DG7	nitrate ABC transporter
M744_08445	ENOG4105D7T	ABC transporter
M744_08450	ENOG4105D7T	ABC transporter
M744_08460	ENOG4105DXN	mazG family
M744_08475	ENOG4105CAS	nag kinase
M744_08495	ENOG410811Q	Ferredoxin
M744_08500	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
M744_08525	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
M744_08540	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
M744_08550	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
M744_08555	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_08565	ENOG4105CVN	desaturase
M744_08570	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
M744_08585	ENOG4105CVJ	phosphoglycerate mutase
M744_08590	ENOG4108YBA	Histidine kinase
M744_08595	ENOG4105C4R	Atp-dependent dna helicase
M744_08605	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
M744_08615	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
M744_08620	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
M744_08625	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
M744_08640	ENOG4108JUA	Transcriptional regulator
M744_08660	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
M744_08665	ENOG4105E0C	molybdate abc transporter
M744_08685	ENOG41089BK	Glutamine amido-transferase
M744_08700	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
M744_08705	ENOG41065W4	chlorophyll a b binding light harvesting protein
M744_08725	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
M744_08735	ENOG4107SCA	Formamidase (EC 3.5.1.49)
M744_08740	ENOG4105KT5	UmuD protein
M744_08745	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
M744_08755	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
M744_08760	ENOG4105DB7	PHP domain protein
M744_08765	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
M744_08770	ENOG4108R9R	May be involved in photosynthetic membrane biogenesis (By similarity)
M744_08780	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_08795	ENOG4108UW5	maltose o-acetyltransferase
M744_08830	ENOG41065RQ	ADP-ribosylation crystallin J1
M744_08870	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
M744_08895	ENOG4105C59	p-type ATPase
M744_08910	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
M744_08925	ENOG4105CMQ	Chloride channel
M744_08930	ENOG4105C75	arginyL-tRNA synthetase
M744_08960	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
M744_08970	ENOG4105CNG	UPF0061 protein
M744_08985	ENOG4105BZU	Histidine kinase
M744_08995	ENOG4105CMQ	Chloride channel
M744_09010	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
M744_09020	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
M744_09025	ENOG4105E6N	shikimate quinate 5-dehydrogenase
M744_09030	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
M744_09040	ENOG4105EUJ	GTP cyclohydrolase i
M744_09045	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
M744_09050	ENOG4105JFG	SpoIID LytB domain protein
M744_09065	ENOG4106FVC	RNA methyltransferase
M744_09095	ENOG4108PWY	Carbohydrate-selective porin OprB
M744_09100	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
M744_09115	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
M744_09120	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
M744_09125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
M744_09140	ENOG4107ETG	50S ribosomal protein L34
M744_09145	ENOG4105UVI	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
M744_09170	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
M744_09185	ENOG4105CFP	Peptidase U32
M744_09195	ENOG4108R6K	riboflavin synthase, subunit alpha
M744_09225	ENOG4105NP4	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
M744_09255	ENOG4108PWY	Carbohydrate-selective porin OprB
M744_09275	ENOG41072GX	Peptidase M22 Glycoprotease
M744_09295	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
M744_09300	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
M744_09305	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
M744_09320	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
M744_09325	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
M744_09330	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
M744_09335	ENOG4107B2H	carbonic anhydrase
M744_09380	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
M744_09385	ENOG4105C8S	subunit m
M744_09410	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
M744_09420	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
M744_09435	ENOG4108ZCU	PPIases accelerate the folding of proteins
M744_09450	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
M744_09460	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
M744_09465	ENOG4105S3V	Carbon dioxide concentrating mechanism protein
M744_09470	ENOG4105MN7	Carbon dioxide concentrating mechanism protein
M744_09475	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
M744_09480	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
M744_09485	ENOG4105KNY	Microcompartments protein
M744_09490	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
M744_09495	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
M744_09510	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
M744_09515	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
M744_09520	ENOG4105C19	ABC transporter
M744_09535	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
M744_09540	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
M744_09545	ENOG4107QKW	extracellular solute-binding protein family 1
M744_09550	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
M744_09555	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
M744_09560	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
M744_09575	ENOG4105ETX	regulatoR
M744_09580	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
M744_09630	ENOG4105DGU	Histone deacetylase
M744_09635	ENOG4105CGH	5'-nucleotidase
M744_09640	ENOG4105C0P	Mg chelatase subunit ChlI
M744_09645	ENOG4107YU2	histidine triad (hIT) protein
M744_09655	ENOG4108UHE	carbonic anhydrase
M744_09665	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
M744_09685	ENOG4105BZU	Histidine kinase
M744_09690	ENOG4105C5H	ABC transporter
M744_09700	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
M744_09710	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
M744_09735	ENOG4105D3G	Pseudouridine synthase
M744_09750	ENOG4105D7N	magnesium and cobalt transport protein CorA
M744_09760	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
M744_09785	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
M744_09810	ENOG4105N7N	Pentapeptide repeat-containing protein
M744_09815	ENOG4108KGH	TRANSCRIPTIONal
M744_09820	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
M744_09825	ENOG4107XWB	Zinc finger, swim domain protein
M744_09840	ENOG4105BZU	Histidine kinase
M744_09845	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
M744_09855	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
M744_09860	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
M744_09880	ENOG4105C5I	Dehydrogenase
M744_09885	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
M744_09890	ENOG4107YX3	NADH dehydrogenase subunit j
M744_09895	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
M744_09900	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
M744_09915	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
M744_09950	ENOG4105CRQ	synthase (Component I)
M744_09955	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
M744_09970	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
M744_09995	ENOG4105CDU	Replicative dna helicase
M744_09995	ENOG4105CDU	Replicative dna helicase
M744_10000	ENOG4105CQR	helicase
M744_10005	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
M744_10010	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
M744_10025	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
M744_10030	ENOG4105CC5	ABC transporter
M744_10035	ENOG4105DIK	(ABC) transporter
M744_10040	ENOG4107SIG	periplasmic solute binding protein
M744_10045	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
M744_10055	ENOG4105C9M	aspartyl-trna synthetase
M744_10075	ENOG4105DUM	transcriptional regulator, lysR family
M744_10125	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
M744_10135	ENOG4105BZU	Histidine kinase
M744_10160	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
M744_10165	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
M744_10170	ENOG4107YCR	Transcriptional regulator, ARSR family
M744_10180	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
M744_10195	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
M744_10200	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
M744_10210	ENOG4108ZAF	Molybdopterin
M744_10215	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
M744_10240	ENOG41084A0	50s ribosomal protein L35
M744_10245	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
M744_10250	ENOG4105CT1	(ABC) transporter
M744_10265	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
M744_10280	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
M744_10285	ENOG4105CJW	magnesium transporter
M744_10295	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
M744_10305	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
M744_10325	ENOG4105DZ0	fad dependent oxidoreductase
M744_10330	ENOG4105CP7	Triose-phosphate isomerase
M744_10335	ENOG4105D0M	Protease HtpX homolog
M744_10360	ENOG4105C9B	Cysteine desulfurase
M744_10375	ENOG4107VRP	DNA repair exonuclease
M744_10380	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
M744_10390	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
M744_10415	ENOG4105EY8	ABC transporter
M744_10430	ENOG4105F04	LysR family Transcriptional regulator
M744_10440	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
M744_10445	ENOG4105I5W	Transporter
M744_10450	ENOG4105DG7	nitrate ABC transporter
M744_10455	ENOG4105D7T	ABC transporter
M744_10460	ENOG4105D7T	ABC transporter
M744_10465	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
M744_10480	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
M744_10485	ENOG4105D1D	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
M744_10490	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
M744_10495	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
M744_10505	ENOG4105W5Q	DNA repair protein (RadC
M744_10515	ENOG4105C1V	Peptidase, M16
M744_10520	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
M744_10525	ENOG4105CW7	secretion protein, HlyD family
M744_10535	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
M744_10540	ENOG4105M3Z	response regulator
M744_10545	ENOG4105K46	50S ribosomal protein l27
M744_10550	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
M744_10555	ENOG4108WXF	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation
M744_10560	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
M744_10565	ENOG4105EHU	Circadian clock protein KaiC
M744_10575	ENOG4108V06	Glutathione peroxidase
M744_10580	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
M744_10615	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
M744_10625	ENOG4105E71	FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
M744_10645	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
M744_10665	ENOG4105DK0	Indole-3-glycerol phosphate synthase
M744_10680	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
M744_10695	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
M744_10700	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
M744_10705	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
M744_10710	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
M744_10740	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M744_10745	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
M744_10750	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M744_10755	ENOG410828V	rubredoxin
M744_10760	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
M744_10765	ENOG4105NT3	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
M744_10770	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
M744_10790	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
M744_10795	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
M744_10805	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
M744_10810	ENOG4108SGF	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
M744_10865	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
M744_10880	ENOG4105E2Y	ABC, transporter
M744_10885	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
M744_10895	ENOG4105CAT	Cytidine monophosphate kinase
M744_10910	ENOG4108IAJ	Nad-dependent epimerase dehydratase
M744_10915	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
M744_10950	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
M744_10970	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
M744_11035	ENOG4105MFV	ABC-2 type transporter
M744_11040	ENOG4105CBS	Chea signal transduction histidine kinase
M744_11050	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
M744_11060	ENOG4107WDG	serine threonine protein kinase
M744_11065	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
M744_11085	ENOG4105BZA	Phosphoglycerate kinase
M744_11095	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
M744_11100	ENOG4105C02	permease
M744_11115	ENOG4108UNF	response regulator
M744_11120	ENOG4107QZB	decarboxylase
M744_11125	ENOG4105K70	DNA-binding protein
M744_11145	ENOG4105CNI	cell division protein FtsW
M744_11150	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
M744_11165	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
M744_11170	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
M744_11175	ENOG4106MP8	UPF0754 membrane protein
M744_11180	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
M744_11195	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
M744_11220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
M744_11225	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
M744_11235	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
M744_11240	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
M744_11250	ENOG4105CND	Glycosyl transferase, family 2
M744_11255	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
M744_11265	ENOG4107ZYR	domain protein
M744_11270	ENOG4105CZN	Potassium uptake protein
M744_11310	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
M744_11335	ENOG4105C7S	Dehydrogenase
M744_11380	ENOG4105CVR	type I restriction-modification system
M744_11395	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
M744_11405	ENOG4108V9J	phycocyanobilin lyase
M744_11410	ENOG41078GB	pbs lyase
M744_11415	ENOG4108SDR	phycocyanin, alpha subunit
M744_11420	ENOG4108RIN	C-phycoerythrin class I beta chain
M744_11440	ENOG4108SDR	phycocyanin, alpha subunit
M744_11445	ENOG4108RIN	C-phycoerythrin class I beta chain
M744_11455	ENOG4105JFG	SpoIID LytB domain protein
M744_11495	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
M744_11535	ENOG4105CIH	Imidazole acetol-phosphate transaminase
M744_11550	ENOG4105CPT	Alpha beta hydrolase
M744_11555	ENOG4105KC4	UPF0296 protein
M744_11560	ENOG4105F23	Fibronectin-binding protein
M744_11565	ENOG4106F1P	AAA ATPase, central domain protein
M744_11580	ENOG4105CEY	Amp-dependent synthetase and ligase
M744_11600	ENOG4105CDY	transcriptional regulatory protein
M744_11615	ENOG4105C8Q	Methyl-accepting chemotaxis
M744_11620	ENOG4105CBS	Chea signal transduction histidine kinase
M744_11635	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
M744_11640	ENOG4105EB3	Histidine kinase
M744_11660	ENOG4105C9Q	fumarate hydratase class II
M744_11695	ENOG4105CFH	Aspartokinase
M744_11710	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
M744_11715	ENOG41068G9	50S ribosomal protein L32
M744_11720	ENOG4105DBI	uridine monophosphokinase
M744_11735	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
M744_11745	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
M744_11765	ENOG4107XWZ	ferric uptake regulator
M744_11780	ENOG4107XHR	Involved in DNA repair and RecF pathway recombination (By similarity)
M744_11785	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
M744_11820	ENOG4107SC0	ferredoxin--NADP reductase
M744_11835	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
M744_11855	ENOG4105EWK	phytoene
M744_11860	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
M744_11870	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
M744_11880	ENOG4107TK4	histidinol-phosphate phosphatase
M744_11895	ENOG4108KGH	TRANSCRIPTIONal
M744_11900	ENOG4108IJ9	(ABC) transporter
M744_11905	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M744_11910	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
M744_11915	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
M744_11920	ENOG4105CKI	cobalamin synthesis protein
M744_11930	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
M744_11950	ENOG4107T3P	ABC, transporter
M744_11965	ENOG4108IJ9	(ABC) transporter
M744_11985	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
M744_11990	ENOG4105C8Y	Acetylornithine aminotransferase
M744_12005	ENOG4105C5H	ABC transporter
M744_12020	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
M744_12030	ENOG4107S76	domain protein
M744_12045	ENOG4108I0Q	anthranilate phosphoribosyltransferase
M744_12055	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
M744_12060	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
M744_12065	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
M744_12070	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
M744_12075	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M744_12080	ENOG4107QPR	SAICAR synthetase
M744_12095	ENOG4105C12	Phosphoribosylglycinamide synthetase
M744_12105	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
M744_12110	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
M744_12130	ENOG4108IQE	Amp-dependent synthetase and ligase
M744_12160	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
M744_12175	ENOG4105C6E	dna polymerase iii
M744_12245	ENOG4105NZG	Ferredoxin
M744_12250	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
M744_12265	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
M744_12275	ENOG4105DF7	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
M744_12295	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
M744_12300	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
M744_12305	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
M744_12310	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
M744_12315	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
M744_12320	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
M744_12330	ENOG4105CQC	Prephenate dehydratase
M744_12340	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
M744_12355	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
M744_12360	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
M744_12370	ENOG4105C0D	helicase
M744_12445	ENOG4105CBS	Chea signal transduction histidine kinase
M744_12460	ENOG4105M3Z	response regulator
M744_12480	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
M744_12485	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
M744_12505	ENOG4105CZX	twitching motility protein
M744_12525	ENOG4105DC8	reductase
M744_12530	ENOG4105H3G	oxidoreductase
M744_12565	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
M744_12600	ENOG4105C5S	asparaginyl-tRNA synthetase
M744_12615	ENOG4107QRP	cobalamin biosynthesis protein CobW
M744_12630	ENOG4105FF5	Membrane
M744_12640	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
M744_12645	ENOG4108J59	Extracellular solute-binding protein, family 5
M744_12655	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
M744_12665	ENOG4105I3K	Ferric uptake regulator, Fur family
M744_12670	ENOG4105BZU	Histidine kinase
M744_12675	ENOG4108IV0	ABC, transporter
M744_12680	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
M744_12685	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
M744_12690	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
M744_12710	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
M744_12730	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
M744_12745	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
M744_12750	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
M744_12760	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
M744_12810	ENOG4107MKT	Stringent starvation protein a
M744_12830	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
M744_12835	ENOG4105BZ1	(ABC) transporter
M744_12860	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
M744_12865	ENOG4105CTB	Polyprenyl synthetase
M744_13125	ENOG4105CFI	type iii restriction protein res subunit
M744_13205	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
M744_13220	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
M744_13230	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
M744_13250	ENOG4105CXN	decarboxylase
M744_13255	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
M744_13280	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
M744_13305	ENOG4105YVZ	photosystem II
M744_13315	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
M744_13320	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
M744_13340	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
M744_13350	ENOG41082YX	Transcriptional regulator, arsr family
M744_13360	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
M744_13370	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
M744_13390	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
M744_13435	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
M744_13450	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_13460	ENOG4105CXT	aspartate transcarbamylase
M744_13465	ENOG4108VX5	3-methyladenine DNA glycosylase
M744_13485	ENOG4107W9I	Creatinine amidohydrolase
M744_13490	ENOG4105EGS	Mechanosensitive ion channel
M744_13495	ENOG4105F8J	Adenylate Guanylate cyclase
M744_13510	ENOG4105EVN	Prephenate dehydrogenase
M744_13530	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
M744_13540	ENOG4108S5W	Seems to be required for the assembly of the photosystem I complex (By similarity)
M744_13565	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
M744_13575	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
M744_13585	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
M744_13590	ENOG4105BZU	Histidine kinase
M744_13620	ENOG4105BZ1	(ABC) transporter
M744_13630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
M744_13640	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
M744_13655	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
M744_13660	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
M744_13670	ENOG4107Z3D	50S ribosomal protein l10
M744_13675	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
M744_13690	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
M744_13710	ENOG4105C01	Dihydroxy-acid dehydratase
M744_13715	ENOG4105CD2	stage iii sporulation protein aa
M744_13725	ENOG4105C3M	thioredoxin reductase
M744_13745	ENOG4107T5V	SNARE associated Golgi
M744_13760	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
M744_13765	ENOG4105C72	UPF0176 protein
M744_13790	ENOG4105D8X	mechanosensitive ion channel
M744_13795	ENOG4105C8S	subunit m
M744_13810	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
M744_13815	ENOG4105FFC	UPF0187 protein
M744_13825	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
M744_13865	ENOG4108IPT	Naphthoate synthase
M744_13890	ENOG4107R1X	phosphohexokinase
M744_13910	ENOG4106E83	A core subunit of photosystem II (PSII) (By similarity)
M744_13915	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
M744_13920	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
M744_14025	ENOG4105CAH	Chromate
M744_14030	ENOG4108302	MgtC SapB transporter
M744_14035	ENOG4107VGR	Catalase
M744_14065	ENOG4105C6T	cysteine synthase
M744_14070	ENOG4105D7W	serine acetyltransferase
M744_14075	ENOG4105ESN	nucleotide-binding protein
M744_14080	ENOG4105C9B	Cysteine desulfurase
M744_14085	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
M744_14100	ENOG4107QMS	site-determining protein
M744_14125	ENOG4107WNA	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
M744_14150	ENOG4105ETX	regulatoR
M744_14155	ENOG4105E0F	Histidine kinase
M744_14175	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein