locus-tag	class	description
Syncc8109_0001	COG0592	DNA-directed DNA polymerase activity
Syncc8109_0004	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Syncc8109_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Syncc8109_0008	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Syncc8109_0011	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Syncc8109_0012	COG0552	protein localization to endoplasmic reticulum
Syncc8109_0013	COG2208	phosphoserine phosphatase activity
Syncc8109_0014	COG0165	Argininosuccinate lyase
Syncc8109_0015	COG0724	RNA recognition motif
Syncc8109_0016	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Syncc8109_0018	COG2081	HI0933 family
Syncc8109_0022	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Syncc8109_0023	COG0484	heat shock protein binding
Syncc8109_0025	COG1162	GTPase activity
Syncc8109_0026	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Syncc8109_0027	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Syncc8109_0028	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Syncc8109_0030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Syncc8109_0031	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Syncc8109_0032	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Syncc8109_0033	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Syncc8109_0034	COG0511	ligase activity, forming carbon-carbon bonds
Syncc8109_0035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Syncc8109_0051	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Syncc8109_0052	COG0519	Catalyzes the synthesis of GMP from XMP
Syncc8109_0052	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Syncc8109_0056	COG0438	transferase activity, transferring glycosyl groups
Syncc8109_0057	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Syncc8109_0059	COG2022	thiamine diphosphate biosynthetic process
Syncc8109_0062	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Syncc8109_0063	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Syncc8109_0064	COG2385	sporulation resulting in formation of a cellular spore
Syncc8109_0065	COG1215	transferase activity, transferring glycosyl groups
Syncc8109_0066	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Syncc8109_0068	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Syncc8109_0069	COG0740	serine-type endopeptidase activity
Syncc8109_0070	COG0544	peptidyl-prolyl cis-trans isomerase activity
Syncc8109_0071	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Syncc8109_0072	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Syncc8109_0073	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Syncc8109_0080	COG2082	Precorrin-8x methylmutase
Syncc8109_0081	COG0037	tRNA processing
Syncc8109_0084	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Syncc8109_0085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Syncc8109_0087	COG0556	nucleotide-excision repair
Syncc8109_0090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Syncc8109_0094	COG0653	protein targeting
Syncc8109_0108	COG1725	Transcriptional regulator
Syncc8109_0112	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Syncc8109_0113	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Syncc8109_0114	COG1372	Participates in initiation and elongation during chromosome replication
Syncc8109_0114	COG0187	DNA topoisomerase II activity
Syncc8109_0116	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Syncc8109_0117	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Syncc8109_0118	COG0386	Belongs to the glutathione peroxidase family
Syncc8109_0119	COG2239	Acts as a magnesium transporter
Syncc8109_0120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Syncc8109_0122	COG1194	a g-specific adenine glycosylase
Syncc8109_0124	COG0802	atpase or kinase
Syncc8109_0125	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Syncc8109_0126	COG0586	Pfam SNARE associated Golgi protein
Syncc8109_0127	COG0629	single-stranded DNA binding
Syncc8109_0129	COG1792	Involved in formation and maintenance of cell shape
Syncc8109_0133	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Syncc8109_0137	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Syncc8109_0138	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Syncc8109_0140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Syncc8109_0141	COG2255	four-way junction helicase activity
Syncc8109_0143	COG1473	amidohydrolase
Syncc8109_0146	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Syncc8109_0147	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Syncc8109_0148	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Syncc8109_0149	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Syncc8109_0150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_0151	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Syncc8109_0153	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Syncc8109_0155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Syncc8109_0156	COG0571	ribonuclease III activity
Syncc8109_0161	COG0058	SHG alpha-glucan phosphorylase activity
Syncc8109_0162	COG0475	glutathione-regulated potassium exporter activity
Syncc8109_0166	COG0277	FAD linked oxidase domain protein
Syncc8109_0168	COG0247	lactate metabolic process
Syncc8109_0169	COG0538	isocitrate dehydrogenase activity
Syncc8109_0172	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Syncc8109_0174	COG5398	heme oxygenase
Syncc8109_0184	COG0709	Synthesizes selenophosphate from selenide and ATP
Syncc8109_0185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Syncc8109_0186	COG0124	histidyl-tRNA synthetase
Syncc8109_0188	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Syncc8109_0194	COG4447	cellulose binding
Syncc8109_0196	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_0197	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_0198	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_0199	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Syncc8109_0200	COG3842	ATPase activity
Syncc8109_0202	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Syncc8109_0202	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Syncc8109_0203	COG4988	ABC transporter
Syncc8109_0204	COG0494	nUDIX hydrolase
Syncc8109_0205	COG0415	Belongs to the DNA photolyase family
Syncc8109_0212	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Syncc8109_0213	COG0131	Imidazoleglycerol-phosphate dehydratase
Syncc8109_0214	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Syncc8109_0218	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Syncc8109_0222	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Syncc8109_0225	COG0354	folic acid binding
Syncc8109_0226	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Syncc8109_0230	COG1253	flavin adenine dinucleotide binding
Syncc8109_0231	COG0673	inositol 2-dehydrogenase activity
Syncc8109_0235	COG0343	queuine tRNA-ribosyltransferase activity
Syncc8109_0236	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Syncc8109_0237	COG2205	protein histidine kinase activity
Syncc8109_0240	COG0138	bifunctional purine biosynthesis protein purh
Syncc8109_0243	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Syncc8109_0244	COG0004	ammonium transporteR
Syncc8109_0245	COG1489	DNA binding
Syncc8109_0246	COG0728	peptidoglycan biosynthetic process
Syncc8109_0252	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Syncc8109_0253	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Syncc8109_0254	COG1058	Belongs to the CinA family
Syncc8109_0254	COG1546	Belongs to the CinA family
Syncc8109_0255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Syncc8109_0256	COG0066	3-isopropylmalate dehydratase activity
Syncc8109_0263	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Syncc8109_0264	COG0193	aminoacyl-tRNA hydrolase activity
Syncc8109_0267	COG4372	Transposase
Syncc8109_0268	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Syncc8109_0269	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Syncc8109_0271	COG0717	Belongs to the dCTP deaminase family
Syncc8109_0273	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Syncc8109_0275	COG0741	lytic transglycosylase activity
Syncc8109_0276	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Syncc8109_0279	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Syncc8109_0284	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Syncc8109_0288	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Syncc8109_0289	COG1402	creatininase
Syncc8109_0291	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Syncc8109_0292	COG2094	Belongs to the DNA glycosylase MPG family
Syncc8109_0293	COG0540	Belongs to the ATCase OTCase family
Syncc8109_0301	COG3536	Protein conserved in bacteria
Syncc8109_0302	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Syncc8109_0305	COG2046	Belongs to the sulfate adenylyltransferase family
Syncc8109_0305	COG0529	Catalyzes the synthesis of activated sulfate
Syncc8109_0306	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Syncc8109_0309	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Syncc8109_0313	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Syncc8109_0315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Syncc8109_0316	COG0436	Aminotransferase
Syncc8109_0318	COG1530	ribonuclease E activity
Syncc8109_0319	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Syncc8109_0322	COG2226	methyltransferase
Syncc8109_0323	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Syncc8109_0324	COG0051	transcription antitermination factor activity, RNA binding
Syncc8109_0325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Syncc8109_0326	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Syncc8109_0327	COG0049	tRNA binding
Syncc8109_0328	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Syncc8109_0329	COG0316	Belongs to the HesB IscA family
Syncc8109_0331	COG0069	glutamate synthase activity
Syncc8109_0331	COG0070	glutamate synthase
Syncc8109_0331	COG0067	glutamate synthase
Syncc8109_0333	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Syncc8109_0337	COG2885	chlorophyll binding
Syncc8109_0338	COG2885	chlorophyll binding
Syncc8109_0345	COG0463	Glycosyl transferase, family 2
Syncc8109_0349	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Syncc8109_0351	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Syncc8109_0352	COG0254	rRNA binding
Syncc8109_0353	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Syncc8109_0354	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Syncc8109_0355	COG0101	tRNA pseudouridine synthase activity
Syncc8109_0356	COG0203	ribosomal protein L17
Syncc8109_0357	COG0202	RNA polymerase activity
Syncc8109_0358	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Syncc8109_0359	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Syncc8109_0360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Syncc8109_0361	COG0563	adenylate kinase activity
Syncc8109_0362	COG0201	protein transport
Syncc8109_0363	COG0200	Binds to the 23S rRNA
Syncc8109_0364	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Syncc8109_0365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Syncc8109_0366	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Syncc8109_0367	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Syncc8109_0368	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Syncc8109_0369	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Syncc8109_0370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Syncc8109_0371	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Syncc8109_0372	COG0255	Belongs to the universal ribosomal protein uL29 family
Syncc8109_0373	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Syncc8109_0374	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Syncc8109_0375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Syncc8109_0376	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Syncc8109_0377	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Syncc8109_0378	COG0089	rRNA binding
Syncc8109_0379	COG0088	Forms part of the polypeptide exit tunnel
Syncc8109_0380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Syncc8109_0385	COG3854	ATPases associated with a variety of cellular activities
Syncc8109_0389	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Syncc8109_0394	COG1233	COG1233 Phytoene dehydrogenase and related
Syncc8109_0403	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Syncc8109_0404	COG1606	tRNA processing
Syncc8109_0405	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Syncc8109_0406	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Syncc8109_0409	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Syncc8109_0410	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Syncc8109_0411	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Syncc8109_0414	COG0772	Belongs to the SEDS family
Syncc8109_0415	COG0489	protein tyrosine kinase activity
Syncc8109_0416	COG0408	coproporphyrinogen oxidase activity
Syncc8109_0420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Syncc8109_0430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Syncc8109_0432	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Syncc8109_0433	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Syncc8109_0433	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Syncc8109_0434	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Syncc8109_0471	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Syncc8109_0498	COG1070	Carbohydrate kinase
Syncc8109_0499	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Syncc8109_0500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Syncc8109_0501	COG0539	negative regulation of cytoplasmic translation
Syncc8109_0502	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Syncc8109_0508	COG0589	response to stress
Syncc8109_0515	COG2890	protein-(glutamine-N5) methyltransferase activity
Syncc8109_0516	COG0009	L-threonylcarbamoyladenylate synthase
Syncc8109_0520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Syncc8109_0521	COG2894	cell division
Syncc8109_0522	COG0850	regulation of cytokinetic process
Syncc8109_0523	COG1078	dGTPase activity
Syncc8109_0524	COG0793	Belongs to the peptidase S41A family
Syncc8109_0525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Syncc8109_0526	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Syncc8109_0536	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Syncc8109_0537	COG0235	Class ii aldolase
Syncc8109_0538	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Syncc8109_0539	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Syncc8109_0542	COG0514	ATP-dependent DNA helicase (RecQ)
Syncc8109_0544	COG1012	belongs to the aldehyde dehydrogenase family
Syncc8109_0548	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Syncc8109_0550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Syncc8109_0554	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Syncc8109_0556	COG0659	secondary active sulfate transmembrane transporter activity
Syncc8109_0557	COG4243	Vitamin k epoxide reductase
Syncc8109_0558	COG0484	heat shock protein binding
Syncc8109_0559	COG0113	porphobilinogen synthase activity
Syncc8109_0561	COG1193	negative regulation of DNA recombination
Syncc8109_0562	COG3842	ATPase activity
Syncc8109_0563	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Syncc8109_0566	COG0488	(ABC) transporter
Syncc8109_0568	COG0435	Glutathione S-transferase
Syncc8109_0569	COG2988	succinylglutamate desuccinylase activity
Syncc8109_0621	COG0523	cobalamin synthesis protein
Syncc8109_0627	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Syncc8109_0629	COG1185	polyribonucleotide nucleotidyltransferase activity
Syncc8109_0630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Syncc8109_0631	COG0750	zinc metalloprotease
Syncc8109_0632	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Syncc8109_0634	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Syncc8109_0636	COG0706	membrane insertase activity
Syncc8109_0638	COG0594	ribonuclease P activity
Syncc8109_0641	COG0616	signal peptide processing
Syncc8109_0642	COG0697	spore germination
Syncc8109_0644	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Syncc8109_0647	COG1842	Phage shock protein A
Syncc8109_0648	COG3118	belongs to the thioredoxin family
Syncc8109_0649	COG0436	Aminotransferase
Syncc8109_0650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Syncc8109_0650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Syncc8109_0653	COG1136	(ABC) transporter
Syncc8109_0653	COG0577	efflux transmembrane transporter activity
Syncc8109_0654	COG1007	ATP synthesis coupled electron transport
Syncc8109_0655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Syncc8109_0658	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Syncc8109_0664	COG1845	cytochrome c oxidase, subunit III
Syncc8109_0667	COG1612	heme a metabolic process
Syncc8109_0668	COG0109	protoheme IX farnesyltransferase activity
Syncc8109_0672	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Syncc8109_0673	COG0459	protein refolding
Syncc8109_0675	COG1028	Short-chain dehydrogenase reductase Sdr
Syncc8109_0678	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Syncc8109_0679	COG1619	proteins homologs of microcin C7 resistance protein MccF
Syncc8109_0680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Syncc8109_0681	COG0248	Ppx GppA phosphatase
Syncc8109_0684	COG2875	Belongs to the precorrin methyltransferase family
Syncc8109_0685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Syncc8109_0686	COG0739	heme binding
Syncc8109_0687	COG0723	plastoquinol--plastocyanin reductase activity
Syncc8109_0689	COG0805	protein transport
Syncc8109_0691	COG0194	GDP metabolic process
Syncc8109_0694	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Syncc8109_0695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Syncc8109_0699	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Syncc8109_0709	COG0335	large ribosomal subunit rRNA binding
Syncc8109_0711	COG0024	Methionine aminopeptidase
Syncc8109_0712	COG0300	oxidoreductase activity
Syncc8109_0712	COG3000	fatty acid hydroxylase
Syncc8109_0714	COG0857	belongs to the CobB CobQ family
Syncc8109_0717	COG1666	GTP binding
Syncc8109_0719	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Syncc8109_0721	COG0295	cytidine deaminase activity
Syncc8109_0723	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Syncc8109_0725	COG0277	FAD linked oxidase domain protein
Syncc8109_0726	COG0708	Exodeoxyribonuclease III
Syncc8109_0731	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Syncc8109_0732	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Syncc8109_0736	COG3842	ATPase activity
Syncc8109_0738	COG0523	cobalamin synthesis protein
Syncc8109_0739	COG2154	pterin-4-alpha-carbinolamine dehydratase
Syncc8109_0740	COG0432	Pfam Uncharacterised protein family UPF0047
Syncc8109_0744	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Syncc8109_0746	COG0181	hydroxymethylbilane synthase activity
Syncc8109_0748	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Syncc8109_0750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Syncc8109_0752	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Syncc8109_0758	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Syncc8109_0759	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Syncc8109_0761	COG0442	prolyl-tRNA aminoacylation
Syncc8109_0765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Syncc8109_0771	COG0588	phosphoglycerate mutase activity
Syncc8109_0774	COG0768	penicillin binding
Syncc8109_0775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Syncc8109_0778	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Syncc8109_0780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Syncc8109_0795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Syncc8109_0804	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Syncc8109_0806	COG2197	response regulator
Syncc8109_0807	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Syncc8109_0810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Syncc8109_0813	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Syncc8109_0814	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Syncc8109_0815	COG0473	3-isopropylmalate dehydrogenase activity
Syncc8109_0816	COG3954	Phosphoribulokinase
Syncc8109_0821	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Syncc8109_0823	COG0673	inositol 2-dehydrogenase activity
Syncc8109_0824	COG0191	fructose-bisphosphate aldolase activity
Syncc8109_0825	COG1619	proteins homologs of microcin C7 resistance protein MccF
Syncc8109_0826	COG0047	phosphoribosylformylglycinamidine synthase activity
Syncc8109_0827	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Syncc8109_0831	COG0668	transmembrane transport
Syncc8109_0833	COG0640	Transcriptional regulator
Syncc8109_0849	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Syncc8109_0852	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Syncc8109_0854	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Syncc8109_0855	COG1429	ligase activity, forming nitrogen-metal bonds
Syncc8109_0857	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Syncc8109_0858	COG0149	triose-phosphate isomerase activity
Syncc8109_0860	COG1132	(ABC) transporter
Syncc8109_0862	COG1115	amino acid carrier protein
Syncc8109_0864	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Syncc8109_0866	COG0799	negative regulation of ribosome biogenesis
Syncc8109_0875	COG0659	secondary active sulfate transmembrane transporter activity
Syncc8109_0877	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Syncc8109_0878	COG4597	amino acid ABC transporter
Syncc8109_0879	COG0765	amino acid transport
Syncc8109_0880	COG1126	abc transporter atp-binding protein
Syncc8109_0888	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Syncc8109_0889	COG2873	o-acetylhomoserine
Syncc8109_0904	COG0735	belongs to the Fur family
Syncc8109_0907	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Syncc8109_0914	COG0123	including yeast histone deacetylase and acetoin utilization protein
Syncc8109_0956	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Syncc8109_0958	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Syncc8109_0964	COG0745	RESPONSE REGULATOR receiver
Syncc8109_0966	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Syncc8109_0967	COG0271	Belongs to the BolA IbaG family
Syncc8109_0970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Syncc8109_0974	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Syncc8109_0977	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Syncc8109_0979	COG0513	Belongs to the DEAD box helicase family
Syncc8109_0982	COG0724	RNA recognition motif
Syncc8109_0984	COG1132	(ABC) transporter
Syncc8109_0985	COG0589	response to stress
Syncc8109_0985	COG0475	glutathione-regulated potassium exporter activity
Syncc8109_0988	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Syncc8109_0989	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Syncc8109_0991	COG0625	glutathione transferase activity
Syncc8109_0995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Syncc8109_0996	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Syncc8109_0997	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Syncc8109_0998	COG0019	diaminopimelate decarboxylase activity
Syncc8109_1000	COG0542	response to heat
Syncc8109_1001	COG0371	Dehydrogenase
Syncc8109_1002	COG2267	carboxylic ester hydrolase activity
Syncc8109_1004	COG0575	Belongs to the CDS family
Syncc8109_1006	COG1982	Orn Lys Arg decarboxylase major
Syncc8109_1007	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Syncc8109_1009	COG0745	RESPONSE REGULATOR receiver
Syncc8109_1010	COG5002	protein histidine kinase activity
Syncc8109_1011	COG1187	pseudouridine synthase activity
Syncc8109_1013	COG1640	4-alpha-glucanotransferase
Syncc8109_1017	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Syncc8109_1022	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Syncc8109_1023	COG1121	(ABC) transporter
Syncc8109_1029	COG0701	Predicted permease
Syncc8109_1039	COG3659	wide pore channel activity
Syncc8109_1051	COG0716	FMN binding
Syncc8109_1056	COG1840	ABC-type Fe3 transport system, periplasmic component
Syncc8109_1057	COG3128	pkhd-type hydroxylase
Syncc8109_1060	COG3659	wide pore channel activity
Syncc8109_1074	COG0405	Gamma-glutamyltransferase
Syncc8109_1100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Syncc8109_1101	COG1611	Belongs to the LOG family
Syncc8109_1119	COG2124	cytochrome p450
Syncc8109_1142	COG0724	RNA recognition motif
Syncc8109_1167	COG0572	uridine kinase
Syncc8109_1171	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Syncc8109_1172	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Syncc8109_1173	COG0803	Belongs to the bacterial solute-binding protein 9 family
Syncc8109_1174	COG1121	(ABC) transporter
Syncc8109_1176	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Syncc8109_1180	COG0494	nUDIX hydrolase
Syncc8109_1186	COG2226	methyltransferase
Syncc8109_1205	COG1201	RNA secondary structure unwinding
Syncc8109_1206	COG1793	dna ligase
Syncc8109_1213	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Syncc8109_1220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Syncc8109_1222	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Syncc8109_1232	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Syncc8109_1237	COG0740	serine-type endopeptidase activity
Syncc8109_1238	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Syncc8109_1239	COG0577	efflux transmembrane transporter activity
Syncc8109_1239	COG1136	(ABC) transporter
Syncc8109_1240	COG0469	pyruvate kinase activity
Syncc8109_1245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Syncc8109_1246	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Syncc8109_1247	COG0446	pyridine nucleotide-disulphide oxidoreductase
Syncc8109_1254	COG1175	transmembrane transport
Syncc8109_1255	COG1653	transport
Syncc8109_1256	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Syncc8109_1257	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Syncc8109_1258	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Syncc8109_1259	COG0326	Molecular chaperone. Has ATPase activity
Syncc8109_1261	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Syncc8109_1262	COG0483	inositol monophosphate 1-phosphatase activity
Syncc8109_1265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Syncc8109_1266	COG0581	inorganic phosphate transmembrane transporter activity
Syncc8109_1267	COG0573	inorganic phosphate transmembrane transporter activity
Syncc8109_1268	COG0443	Heat shock 70 kDa protein
Syncc8109_1269	COG0484	heat shock protein binding
Syncc8109_1271	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Syncc8109_1272	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Syncc8109_1273	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Syncc8109_1274	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Syncc8109_1274	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Syncc8109_1276	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Syncc8109_1277	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Syncc8109_1284	COG0166	Belongs to the GPI family
Syncc8109_1285	COG0495	leucyl-tRNA aminoacylation
Syncc8109_1287	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Syncc8109_1288	COG1104	cysteine desulfurase activity
Syncc8109_1291	COG2027	D-alanyl-D-alanine carboxypeptidase
Syncc8109_1293	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Syncc8109_1295	COG0322	excinuclease ABC activity
Syncc8109_1297	COG3046	protein related to deoxyribodipyrimidine photolyase
Syncc8109_1302	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Syncc8109_1303	COG0646	methionine synthase
Syncc8109_1303	COG1410	methionine synthase
Syncc8109_1309	COG2385	sporulation resulting in formation of a cellular spore
Syncc8109_1322	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Syncc8109_1323	COG0072	phenylalanine-tRNA ligase activity
Syncc8109_1324	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Syncc8109_1325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Syncc8109_1326	COG0557	exoribonuclease II activity
Syncc8109_1328	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Syncc8109_1335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Syncc8109_1336	COG0739	heme binding
Syncc8109_1339	COG0450	alkyl hydroperoxide reductase
Syncc8109_1340	COG1615	UPF0182 protein
Syncc8109_1341	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Syncc8109_1343	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Syncc8109_1346	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Syncc8109_1347	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Syncc8109_1347	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Syncc8109_1350	COG2119	membrane
Syncc8109_1353	COG0557	exoribonuclease II activity
Syncc8109_1354	COG0163	prenyltransferase activity
Syncc8109_1357	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Syncc8109_1358	COG0312	modulator of DNA gyrase
Syncc8109_1360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Syncc8109_1363	COG0861	Integral membrane protein TerC family
Syncc8109_1379	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Syncc8109_1387	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Syncc8109_1389	COG0793	Belongs to the peptidase S41A family
Syncc8109_1390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Syncc8109_1391	COG1573	uracil-dna glycosylase
Syncc8109_1393	COG0436	Aminotransferase
Syncc8109_1394	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Syncc8109_1395	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Syncc8109_1401	COG1836	PFAM Integral membrane protein DUF92
Syncc8109_1405	COG1122	ATPase activity
Syncc8109_1406	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Syncc8109_1409	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Syncc8109_1410	COG4106	trans-aconitate 2-methyltransferase activity
Syncc8109_1420	COG0300	oxidoreductase activity
Syncc8109_1429	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Syncc8109_1431	COG0129	dihydroxy-acid dehydratase activity
Syncc8109_1434	COG0363	glucosamine-6-phosphate deaminase activity
Syncc8109_1435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Syncc8109_1436	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Syncc8109_1437	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Syncc8109_1438	COG1494	fructose-1,6-bisphosphatase
Syncc8109_1439	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Syncc8109_1442	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Syncc8109_1444	COG1137	ATPase activity
Syncc8109_1448	COG0826	peptidase U32
Syncc8109_1450	COG0644	oxidoreductase
Syncc8109_1452	COG0751	glycine-tRNA ligase activity
Syncc8109_1453	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Syncc8109_1454	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Syncc8109_1455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Syncc8109_1457	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Syncc8109_1458	COG0052	Belongs to the universal ribosomal protein uS2 family
Syncc8109_1459	COG1216	Glycosyl transferase, family 2
Syncc8109_1465	COG0612	Peptidase, M16
Syncc8109_1466	COG0612	Peptidase, M16
Syncc8109_1469	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Syncc8109_1472	COG0590	tRNA wobble adenosine to inosine editing
Syncc8109_1473	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Syncc8109_1475	COG0174	glutamine synthetase
Syncc8109_1476	COG2226	methyltransferase
Syncc8109_1481	COG0515	serine threonine protein kinase
Syncc8109_1482	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Syncc8109_1484	COG0628	permease
Syncc8109_1489	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Syncc8109_1490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Syncc8109_1491	COG0022	dehydrogenase e1 component
Syncc8109_1491	COG0508	dehydrogenase complex catalyzes the overall conversion of
Syncc8109_1495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Syncc8109_1496	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Syncc8109_1509	COG0792	nuclease activity
Syncc8109_1512	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Syncc8109_1516	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Syncc8109_1520	COG0358	DNA primase activity
Syncc8109_1523	COG0632	four-way junction helicase activity
Syncc8109_1524	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Syncc8109_1526	COG0587	DNA-directed DNA polymerase activity
Syncc8109_1527	COG0154	amidase activity
Syncc8109_1529	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Syncc8109_1530	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Syncc8109_1532	COG0505	Belongs to the CarA family
Syncc8109_1533	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Syncc8109_1534	COG1132	(ABC) transporter
Syncc8109_1538	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Syncc8109_1545	COG2176	DNA-directed DNA polymerase activity
Syncc8109_1547	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Syncc8109_1549	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Syncc8109_1550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Syncc8109_1551	COG0142	geranyltranstransferase activity
Syncc8109_1552	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Syncc8109_1554	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Syncc8109_1555	COG2045	Belongs to the ComB family
Syncc8109_1556	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Syncc8109_1557	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Syncc8109_1559	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Syncc8109_1560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Syncc8109_1562	COG0297	glycogen (starch) synthase activity
Syncc8109_1565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Syncc8109_1566	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Syncc8109_1567	COG0681	Belongs to the peptidase S26 family
Syncc8109_1571	COG0798	PFAM Bile acid sodium symporter
Syncc8109_1620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Syncc8109_1652	COG0180	Tryptophanyl-tRNA synthetase
Syncc8109_1656	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Syncc8109_1659	COG0083	homoserine kinase activity
Syncc8109_1660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_1661	COG0339	signal peptide processing
Syncc8109_1664	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Syncc8109_1665	COG1940	carbohydrate kinase activity
Syncc8109_1671	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Syncc8109_1672	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Syncc8109_1674	COG3794	PFAM blue (type 1) copper domain protein
Syncc8109_1681	COG0542	response to heat
Syncc8109_1683	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Syncc8109_1683	COG0140	phosphoribosyl-ATP diphosphatase activity
Syncc8109_1688	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Syncc8109_1695	COG2010	Cytochrome c
Syncc8109_1698	COG0159	tryptophan synthase activity
Syncc8109_1703	COG0418	dihydroorotase activity
Syncc8109_1704	COG0659	secondary active sulfate transmembrane transporter activity
Syncc8109_1707	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Syncc8109_1712	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Syncc8109_1713	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Syncc8109_1716	COG0456	acetyltransferase
Syncc8109_1717	COG1132	(ABC) transporter
Syncc8109_1718	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Syncc8109_1719	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Syncc8109_1760	COG0582	viral genome integration into host DNA
Syncc8109_1775	COG3239	Fatty acid desaturase
Syncc8109_1812	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Syncc8109_1815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Syncc8109_1816	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Syncc8109_1817	COG2135	peptidase activity
Syncc8109_1819	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Syncc8109_1819	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Syncc8109_1828	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Syncc8109_1829	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Syncc8109_1830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Syncc8109_1832	COG0196	riboflavin kinase activity
Syncc8109_1834	COG0352	thiamine-phosphate diphosphorylase activity
Syncc8109_1838	COG1691	(AIR) carboxylase
Syncc8109_1840	COG0336	Belongs to the RNA methyltransferase TrmD family
Syncc8109_1842	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Syncc8109_1844	COG0670	Belongs to the BI1 family
Syncc8109_1845	COG1702	phosphate starvation-inducible protein PhoH
Syncc8109_1846	COG0228	four-way junction DNA binding
Syncc8109_1847	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Syncc8109_1849	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Syncc8109_1850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Syncc8109_1851	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Syncc8109_1851	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Syncc8109_1852	COG0482	sulfurtransferase activity
Syncc8109_1853	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Syncc8109_1860	COG0134	indole-3-glycerol-phosphate synthase activity
Syncc8109_1861	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Syncc8109_1862	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Syncc8109_1865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Syncc8109_1867	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Syncc8109_1868	COG0285	dihydrofolate synthase activity
Syncc8109_1875	COG4948	Mandelate Racemase Muconate Lactonizing
Syncc8109_1876	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Syncc8109_1877	COG1181	Belongs to the D-alanine--D-alanine ligase family
Syncc8109_1880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Syncc8109_1882	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Syncc8109_1885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Syncc8109_1886	COG4956	integral membrane protein (PIN domain superfamily)
Syncc8109_1887	COG0740	serine-type endopeptidase activity
Syncc8109_1888	COG0740	serine-type endopeptidase activity
Syncc8109_1889	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Syncc8109_1890	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Syncc8109_1892	COG0438	transferase activity, transferring glycosyl groups
Syncc8109_1899	COG0752	glycyl-tRNA synthetase alpha subunit
Syncc8109_1901	COG2226	methyltransferase
Syncc8109_1902	COG0107	imidazoleglycerol-phosphate synthase activity
Syncc8109_1904	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Syncc8109_1905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Syncc8109_1906	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Syncc8109_1906	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Syncc8109_1907	COG3695	enzyme binding
Syncc8109_1908	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Syncc8109_1911	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Syncc8109_1913	COG0481	GTPase activity
Syncc8109_1915	COG0579	oxidoreductase
Syncc8109_1916	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Syncc8109_1933	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Syncc8109_1935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Syncc8109_1936	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Syncc8109_1938	COG0424	maF-like protein
Syncc8109_1940	COG1492	cobalamin metabolic process
Syncc8109_1946	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_1947	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Syncc8109_1954	COG4451	ribulose bisphosphate carboxylase, small
Syncc8109_1955	COG1850	ribulose-bisphosphate carboxylase activity
Syncc8109_1957	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Syncc8109_1961	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Syncc8109_1962	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Syncc8109_1963	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Syncc8109_1968	COG0730	response to heat
Syncc8109_1969	COG0095	Lipoate-protein ligase
Syncc8109_1970	COG1994	Peptidase M50
Syncc8109_1970	COG0517	IMP dehydrogenase activity
Syncc8109_1971	COG0135	phosphoribosylanthranilate isomerase activity
Syncc8109_1972	COG0302	gtp cyclohydrolase
Syncc8109_1973	COG1028	Short-chain dehydrogenase reductase Sdr
Syncc8109_1974	COG0825	malonyl-CoA metabolic process
Syncc8109_1975	COG5322	oxidoreductase activity
Syncc8109_1976	COG3396	Phenylacetate-CoA oxygenase
Syncc8109_1978	COG0539	negative regulation of cytoplasmic translation
Syncc8109_1981	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Syncc8109_1985	COG0028	Belongs to the TPP enzyme family
Syncc8109_1986	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Syncc8109_1991	COG0528	UMP kinase activity
Syncc8109_1992	COG0233	cytoplasmic translational termination
Syncc8109_1994	COG0415	Belongs to the DNA photolyase family
Syncc8109_2006	COG0308	aminopeptidase N
Syncc8109_2009	COG2205	protein histidine kinase activity
Syncc8109_2012	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Syncc8109_2013	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Syncc8109_2015	COG1797	cobyrinic acid a,c-diamide synthase activity
Syncc8109_2016	COG1254	Belongs to the acylphosphatase family
Syncc8109_2019	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Syncc8109_2024	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Syncc8109_2025	COG1480	7TM receptor with intracellular HD hydrolase
Syncc8109_2029	COG0011	TIGRFAM Protein of
Syncc8109_2033	COG0395	ABC-type sugar transport system, permease component
Syncc8109_2034	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Syncc8109_2035	COG1543	Belongs to the glycosyl hydrolase 57 family
Syncc8109_2036	COG0644	oxidoreductase
Syncc8109_2037	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Syncc8109_2038	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Syncc8109_2039	COG0516	GMP reductase activity
Syncc8109_2040	COG3118	belongs to the thioredoxin family
Syncc8109_2041	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Syncc8109_2042	COG0742	ribosomal rna small subunit methyltransferase
Syncc8109_2043	COG2010	Cytochrome c
Syncc8109_2044	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Syncc8109_2047	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Syncc8109_2048	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Syncc8109_2049	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Syncc8109_2051	COG2166	iron-sulfur cluster assembly
Syncc8109_2052	COG0460	homoserine dehydrogenase
Syncc8109_2054	COG0747	negative chemotaxis
Syncc8109_2063	COG0012	GTP binding
Syncc8109_2065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Syncc8109_2065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Syncc8109_2066	COG0215	cysteine-tRNA ligase activity
Syncc8109_2068	COG0733	neurotransmitter:sodium symporter activity
Syncc8109_2069	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Syncc8109_2070	COG3411	Ferredoxin
Syncc8109_2073	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Syncc8109_2075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Syncc8109_2081	COG0492	ferredoxin-NADP+ reductase activity
Syncc8109_2082	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Syncc8109_2086	COG2226	methyltransferase
Syncc8109_2088	COG0702	epimerase
Syncc8109_2091	COG2267	carboxylic ester hydrolase activity
Syncc8109_2092	COG0440	acetolactate synthase activity
Syncc8109_2093	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Syncc8109_2099	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Syncc8109_2100	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Syncc8109_2103	COG1022	Amp-dependent synthetase and ligase
Syncc8109_2104	COG0321	lipoyl(octanoyl) transferase activity
Syncc8109_2105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Syncc8109_2106	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Syncc8109_2107	COG1381	Involved in DNA repair and RecF pathway recombination
Syncc8109_2108	COG2814	Major facilitator Superfamily
Syncc8109_2113	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Syncc8109_2115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Syncc8109_2116	COG1799	cell septum assembly
Syncc8109_2117	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Syncc8109_2119	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Syncc8109_2120	COG1160	GTP binding
Syncc8109_2124	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Syncc8109_2127	COG1091	dTDP-4-dehydrorhamnose reductase activity
Syncc8109_2128	COG1088	dTDP-glucose 4,6-dehydratase activity
Syncc8109_2129	COG0114	fumarate hydratase activity
Syncc8109_2134	COG0385	Bile acid
Syncc8109_2135	COG0156	8-amino-7-oxononanoate synthase activity
Syncc8109_2138	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Syncc8109_2141	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Syncc8109_2144	COG0357	Ribosomal RNA small subunit methyltransferase G
Syncc8109_2153	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Syncc8109_2154	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Syncc8109_2155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Syncc8109_2156	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Syncc8109_2157	COG0085	RNA polymerase activity
Syncc8109_2158	COG0084	hydrolase, TatD family'
Syncc8109_2159	COG0268	Binds directly to 16S ribosomal RNA
Syncc8109_2160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Syncc8109_2161	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Syncc8109_2162	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Syncc8109_2165	COG0779	Required for maturation of 30S ribosomal subunits
Syncc8109_2166	COG0195	Participates in both transcription termination and antitermination
Syncc8109_2168	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Syncc8109_2178	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Syncc8109_2179	COG0776	regulation of translation
Syncc8109_2183	COG2211	Major facilitator Superfamily
Syncc8109_2184	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Syncc8109_2187	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Syncc8109_2188	COG0284	orotidine-5'-phosphate decarboxylase activity
Syncc8109_2189	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Syncc8109_2195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Syncc8109_2203	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Syncc8109_2205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Syncc8109_2206	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Syncc8109_2207	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Syncc8109_2209	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Syncc8109_2211	COG0151	Belongs to the GarS family
Syncc8109_2212	COG5002	protein histidine kinase activity
Syncc8109_2213	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Syncc8109_2214	COG4251	negative regulation of phosphorylation
Syncc8109_2217	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Syncc8109_2218	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Syncc8109_2220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Syncc8109_2221	COG0217	transcriptional regulatory protein
Syncc8109_2224	COG0363	glucosamine-6-phosphate deaminase activity
Syncc8109_2225	COG2247	cell wall binding repeat
Syncc8109_2225	COG2385	sporulation resulting in formation of a cellular spore
Syncc8109_2226	COG1234	tRNA 3'-trailer cleavage
Syncc8109_2227	COG2010	Cytochrome c
Syncc8109_2230	COG2264	protein methyltransferase activity
Syncc8109_2231	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Syncc8109_2236	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Syncc8109_2242	COG0443	Heat shock 70 kDa protein
Syncc8109_2245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Syncc8109_2246	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Syncc8109_2250	COG0459	protein refolding
Syncc8109_2251	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Syncc8109_2252	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Syncc8109_2253	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Syncc8109_2257	COG0006	proline dipeptidase activity
Syncc8109_2258	COG1253	flavin adenine dinucleotide binding
Syncc8109_2259	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Syncc8109_2260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Syncc8109_2261	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Syncc8109_2261	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Syncc8109_2262	COG0686	Belongs to the AlaDH PNT family
Syncc8109_2263	COG3012	SEC-C Motif Domain Protein
Syncc8109_2264	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Syncc8109_2266	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Syncc8109_2268	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Syncc8109_2269	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Syncc8109_2270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Syncc8109_2271	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Syncc8109_2273	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Syncc8109_2274	COG0356	it plays a direct role in the translocation of protons across the membrane
Syncc8109_2276	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Syncc8109_2277	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Syncc8109_2284	COG0772	Belongs to the SEDS family
Syncc8109_2286	COG1333	cytochrome c biogenesis protein
Syncc8109_2287	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Syncc8109_2289	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Syncc8109_2336	COG0116	Belongs to the methyltransferase superfamily
Syncc8109_2341	COG1196	nuclear chromosome segregation
Syncc8109_2343	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Syncc8109_2347	COG0439	Biotin carboxylase
Syncc8109_2350	COG0515	serine threonine protein kinase
Syncc8109_2353	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Syncc8109_2354	COG4178	(ABC) transporter
Syncc8109_2355	COG0537	adenosine 5'-monophosphoramidase activity
Syncc8109_2360	COG0242	peptide deformylase activity
Syncc8109_2363	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Syncc8109_2364	COG0719	Fe-S assembly protein
Syncc8109_2365	COG0396	ATPase activity
Syncc8109_2366	COG0719	Fe-S assembly protein
Syncc8109_2367	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
Syncc8109_2372	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Syncc8109_2381	COG0033	Phosphoglucomutase
Syncc8109_2383	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Syncc8109_2385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Syncc8109_2389	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Syncc8109_2390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Syncc8109_2391	COG0175	sulfate reduction
Syncc8109_2392	COG1252	NADH dehydrogenase
Syncc8109_2393	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Syncc8109_2394	COG0471	metal ion transport
Syncc8109_2394	COG3273	potassium ion transport
Syncc8109_2395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Syncc8109_2396	COG0569	domain protein
Syncc8109_2397	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Syncc8109_2402	COG0488	(ABC) transporter
Syncc8109_2404	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Syncc8109_2408	COG1643	Atp-dependent helicase
Syncc8109_2409	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Syncc8109_2411	COG1570	exodeoxyribonuclease VII activity
Syncc8109_2412	COG1722	exodeoxyribonuclease VII activity
Syncc8109_2427	COG1968	undecaprenyl-diphosphatase activity
Syncc8109_2429	COG1555	photosystem II stabilization
Syncc8109_2430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Syncc8109_2431	COG4243	Vitamin k epoxide reductase
Syncc8109_2432	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Syncc8109_2443	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Syncc8109_2454	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Syncc8109_2455	COG1472	Belongs to the glycosyl hydrolase 3 family
Syncc8109_2456	COG0463	Glycosyl transferase, family 2
Syncc8109_2456	COG0457	Tetratricopeptide repeat
Syncc8109_2457	COG1587	Uroporphyrinogen-III synthase
Syncc8109_2460	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Syncc8109_2461	COG0316	Belongs to the HesB IscA family
Syncc8109_2466	COG1090	epimerase
Syncc8109_2469	COG0484	heat shock protein binding
Syncc8109_2470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Syncc8109_2471	COG3659	wide pore channel activity
Syncc8109_2472	COG3659	wide pore channel activity
Syncc8109_2476	COG0463	Glycosyl transferase, family 2
Syncc8109_2484	COG1122	ATPase activity
Syncc8109_2487	COG0745	RESPONSE REGULATOR receiver
Syncc8109_2489	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Syncc8109_2490	COG2217	Heavy metal translocating P-type atpase
Syncc8109_2491	COG3063	Type IV pilus biogenesis stability protein PilW
Syncc8109_2492	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Syncc8109_2494	COG0416	fatty acid biosynthetic process
Syncc8109_2495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Syncc8109_2496	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Syncc8109_2497	COG0318	PFAM AMP-dependent synthetase and ligase
Syncc8109_2497	COG0204	Acyl-transferase
Syncc8109_2499	COG1214	PFAM Peptidase M22, glycoprotease
Syncc8109_2502	COG0724	RNA recognition motif
Syncc8109_2503	COG1562	ergosterol biosynthetic process
Syncc8109_2504	COG0493	'glutamate synthase
Syncc8109_2504	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Syncc8109_2507	COG0583	DNA-binding transcription factor activity
Syncc8109_2509	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Syncc8109_2510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_2513	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Syncc8109_2515	COG2197	response regulator
Syncc8109_2518	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Syncc8109_2519	COG0713	ATP synthesis coupled electron transport
Syncc8109_2520	COG0839	Belongs to the complex I subunit 6 family
Syncc8109_2521	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Syncc8109_2522	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Syncc8109_2523	COG0372	Belongs to the citrate synthase family
Syncc8109_2527	COG1420	regulation of RNA biosynthetic process
Syncc8109_2528	COG0133	tryptophan synthase activity
Syncc8109_2529	COG0023	Translation Initiation Factor
Syncc8109_2530	COG0529	Catalyzes the synthesis of activated sulfate
Syncc8109_2531	COG0628	permease
Syncc8109_2534	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Syncc8109_2536	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Syncc8109_2537	COG0564	pseudouridine synthase activity
Syncc8109_2538	COG0745	RESPONSE REGULATOR receiver
Syncc8109_2540	COG1104	cysteine desulfurase activity
Syncc8109_2541	COG0275	rRNA processing
Syncc8109_2542	COG0649	NAD binding
Syncc8109_2544	COG0824	Thioesterase
Syncc8109_2546	COG0318	PFAM AMP-dependent synthetase and ligase
Syncc8109_2548	COG1575	Belongs to the MenA family. Type 1 subfamily
Syncc8109_2550	COG0189	ligase activity
Syncc8109_2551	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Syncc8109_2552	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Syncc8109_2554	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Syncc8109_2555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Syncc8109_2556	COG0512	Glutamine amidotransferase of anthranilate synthase
Syncc8109_2558	COG0252	asparaginase activity
Syncc8109_2559	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Syncc8109_2560	COG0018	arginyl-trna synthetase
Syncc8109_2561	COG0157	Belongs to the NadC ModD family
Syncc8109_2562	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Syncc8109_2564	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Syncc8109_2565	COG4172	Belongs to the ABC transporter superfamily
Syncc8109_2566	COG0564	pseudouridine synthase activity
Syncc8109_2567	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Syncc8109_2568	COG0126	phosphoglycerate kinase activity
Syncc8109_2571	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Syncc8109_2572	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Syncc8109_2573	COG0167	dihydroorotate dehydrogenase activity
Syncc8109_2574	COG0328	RNA-DNA hybrid ribonuclease activity
Syncc8109_2577	COG0222	ribosome binding
Syncc8109_2578	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Syncc8109_2580	COG0081	regulation of translation
Syncc8109_2581	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Syncc8109_2582	COG0250	Participates in transcription elongation, termination and antitermination
Syncc8109_2583	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Syncc8109_2584	COG0542	response to heat
Syncc8109_2585	COG0346	lactoylglutathione lyase activity
Syncc8109_2586	COG0148	phosphopyruvate hydratase activity
Syncc8109_2587	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Syncc8109_2592	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Syncc8109_2593	COG0237	dephospho-CoA kinase activity
Syncc8109_2595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Syncc8109_2596	COG2022	thiamine diphosphate biosynthetic process
Syncc8109_2596	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Syncc8109_2597	COG0105	UTP biosynthetic process
Syncc8109_2598	COG1166	arginine decarboxylase activity
Syncc8109_2599	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Syncc8109_2601	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Syncc8109_2607	COG0426	domain, Protein
Syncc8109_2607	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Syncc8109_2608	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Syncc8109_2608	COG0426	domain, Protein
Syncc8109_2610	COG1773	rubredoxin
Syncc8109_2612	COG1741	Belongs to the pirin family
Syncc8109_2615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Syncc8109_2615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Syncc8109_2616	COG0509	glycine decarboxylation via glycine cleavage system
Syncc8109_2617	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Syncc8109_2619	COG0359	binds to the 23S rRNA
Syncc8109_2620	COG0305	Participates in initiation and elongation during chromosome replication
Syncc8109_2620	COG0305	Participates in initiation and elongation during chromosome replication
Syncc8109_2620	COG1372	Participates in initiation and elongation during chromosome replication
Syncc8109_2620	COG1372	Participates in initiation and elongation during chromosome replication
Syncc8109_2621	COG0445	tRNA wobble uridine modification
Syncc8109_2629	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Syncc8109_2631	COG0398	Pfam SNARE associated Golgi protein
Syncc8109_2634	COG1131	(ABC) transporter
Syncc8109_2635	COG0525	valine-tRNA ligase activity
Syncc8109_2639	COG4221	oxidoreductase activity
Syncc8109_2651	COG3956	TIGRFAM MazG family protein
Syncc8109_2652	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Syncc8109_2655	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Syncc8109_2656	COG0010	Belongs to the arginase family
Syncc8109_2659	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Syncc8109_2660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Syncc8109_2661	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Syncc8109_2662	COG0504	CTP synthase activity
Syncc8109_2663	COG0602	queuosine metabolic process
Syncc8109_2665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Syncc8109_2669	COG0366	Alpha amylase catalytic
Syncc8109_2670	COG0463	Glycosyl transferase, family 2
Syncc8109_2675	COG0410	ABC transporter
Syncc8109_2680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Syncc8109_2681	COG0830	nickel cation binding
Syncc8109_2682	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Syncc8109_2684	COG0829	nickel cation binding
Syncc8109_2685	COG0831	urea catabolic process
Syncc8109_2686	COG0832	Belongs to the urease beta subunit family
Syncc8109_2687	COG0804	urea catabolic process
Syncc8109_2688	COG0519	Catalyzes the synthesis of GMP from XMP
Syncc8109_2688	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Syncc8109_2693	COG0367	asparagine synthase
Syncc8109_2694	COG0540	Belongs to the ATCase OTCase family
Syncc8109_2698	COG2308	Evidence 4 Homologs of previously reported genes of
Syncc8109_2702	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Syncc8109_2703	COG0746	molybdenum cofactor guanylyltransferase activity
Syncc8109_2706	COG2223	nitrite transmembrane transporter activity
Syncc8109_2707	COG0243	molybdopterin cofactor binding
Syncc8109_2712	COG0315	cyclic pyranopterin monophosphate synthase activity
Syncc8109_2713	COG0303	'Molybdopterin
Syncc8109_2716	COG0314	molybdopterin synthase activity
Syncc8109_2718	COG0521	Mo-molybdopterin cofactor biosynthetic process
Syncc8109_2719	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Syncc8109_2723	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Syncc8109_2725	COG2116	formate transmembrane transporter activity
Syncc8109_2727	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Syncc8109_2730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Syncc8109_2733	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Syncc8109_2734	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Syncc8109_2735	COG0170	dolichyl monophosphate biosynthetic process
Syncc8109_2736	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Syncc8109_2737	COG1049	propionate catabolic process, 2-methylcitrate cycle
Syncc8109_2741	COG0788	formyltetrahydrofolate deformylase activity
Syncc8109_2744	COG0443	Heat shock 70 kDa protein
Syncc8109_2745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Syncc8109_2747	COG0360	Binds together with S18 to 16S ribosomal RNA
Syncc8109_2749	COG0137	argininosuccinate synthase activity
Syncc8109_2752	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Syncc8109_2756	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Syncc8109_2757	COG0438	transferase activity, transferring glycosyl groups
Syncc8109_2760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Syncc8109_2761	COG0497	DNA recombination
Syncc8109_2762	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Syncc8109_2764	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine