locus-tag	class	description
C7I86_00005	COG0142	geranyltranstransferase activity
C7I86_00010	COG1187	pseudouridine synthase activity
C7I86_00020	COG0515	serine threonine protein kinase
C7I86_00025	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7I86_00030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7I86_00035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C7I86_00045	COG1166	arginine decarboxylase activity
C7I86_00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7I86_00060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7I86_00065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7I86_00070	COG1120	ATPase activity
C7I86_00075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7I86_00085	COG4977	sequence-specific DNA binding
C7I86_00110	COG2207	Transcriptional regulator
C7I86_00115	COG2226	methyltransferase
C7I86_00125	COG0848	biopolymer transport protein
C7I86_00130	COG0811	peptide transport
C7I86_00145	COG1132	(ABC) transporter
C7I86_00160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7I86_00165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7I86_00175	COG1132	(ABC) transporter
C7I86_00225	COG0409	Hydrogenase expression formation protein
C7I86_00230	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7I86_00235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7I86_00240	COG0297	glycogen (starch) synthase activity
C7I86_00255	COG1131	(ABC) transporter
C7I86_00270	COG2318	DinB family
C7I86_00290	COG1214	PFAM Peptidase M22, glycoprotease
C7I86_00310	COG1615	UPF0182 protein
C7I86_00325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7I86_00330	COG0563	adenylate kinase activity
C7I86_00335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7I86_00355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7I86_00370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7I86_00375	COG0194	GDP metabolic process
C7I86_00380	COG0406	alpha-ribazole phosphatase activity
C7I86_00390	COG0730	response to heat
C7I86_00395	COG1413	lyase activity
C7I86_00410	COG0330	HflC and HflK could
C7I86_00415	COG1530	ribonuclease E activity
C7I86_00420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7I86_00425	COG0494	nUDIX hydrolase
C7I86_00430	COG1185	polyribonucleotide nucleotidyltransferase activity
C7I86_00435	COG0681	Belongs to the peptidase S26 family
C7I86_00450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7I86_00460	COG1401	restriction endodeoxyribonuclease activity
C7I86_00470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7I86_00475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7I86_00520	COG1104	cysteine desulfurase activity
C7I86_00545	COG0582	viral genome integration into host DNA
C7I86_00555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_00555	COG2022	thiamine diphosphate biosynthetic process
C7I86_00565	COG5002	protein histidine kinase activity
C7I86_00575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7I86_00595	COG0704	Plays a role in the regulation of phosphate uptake
C7I86_00600	COG0779	Required for maturation of 30S ribosomal subunits
C7I86_00605	COG0195	Participates in both transcription termination and antitermination
C7I86_00615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7I86_00655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7I86_00665	COG0011	TIGRFAM Protein of
C7I86_00675	COG0589	response to stress
C7I86_00685	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7I86_00690	COG0010	Belongs to the arginase family
C7I86_00695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7I86_00735	COG2099	Precorrin-6x reductase
C7I86_00750	COG1007	ATP synthesis coupled electron transport
C7I86_00770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7I86_00775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7I86_00780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_00780	COG0426	domain, Protein
C7I86_00790	COG0426	domain, Protein
C7I86_00790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_00800	COG0793	Belongs to the peptidase S41A family
C7I86_00805	COG0009	L-threonylcarbamoyladenylate synthase
C7I86_00810	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
C7I86_00815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7I86_00820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7I86_00825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7I86_00830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7I86_00840	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7I86_00845	COG0356	it plays a direct role in the translocation of protons across the membrane
C7I86_00855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_00870	COG0714	Associated with various cellular activities
C7I86_00875	COG0316	Belongs to the HesB IscA family
C7I86_00880	COG0697	spore germination
C7I86_00890	COG1127	ABC transporter
C7I86_00900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7I86_00925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7I86_00940	COG0163	prenyltransferase activity
C7I86_00950	COG0589	response to stress
C7I86_00960	COG5001	Diguanylate cyclase
C7I86_00960	COG1716	ATPase activity
C7I86_00985	COG1234	tRNA 3'-trailer cleavage
C7I86_00995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7I86_01010	COG0631	protein serine/threonine phosphatase activity
C7I86_01020	COG4451	ribulose bisphosphate carboxylase, small
C7I86_01020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7I86_01025	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C7I86_01030	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_01035	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_01040	COG0493	'glutamate synthase
C7I86_01085	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
C7I86_01085	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
C7I86_01100	COG1982	Orn Lys Arg decarboxylase major
C7I86_01105	COG0686	Belongs to the AlaDH PNT family
C7I86_01110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7I86_01130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7I86_01140	COG0673	inositol 2-dehydrogenase activity
C7I86_01145	COG0700	Nucleoside recognition
C7I86_01150	COG2715	membrane protein required for spore maturation
C7I86_01155	COG1640	4-alpha-glucanotransferase
C7I86_01165	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7I86_01180	COG5001	Diguanylate cyclase
C7I86_01180	COG4251	negative regulation of phosphorylation
C7I86_01180	COG3706	GGDEF domain
C7I86_01180	COG2203	Gaf domain
C7I86_01205	COG0175	sulfate reduction
C7I86_01210	COG1420	regulation of RNA biosynthetic process
C7I86_01220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7I86_01225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7I86_01235	COG0003	Pfam Anion-transporting ATPase
C7I86_01240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7I86_01255	COG0484	heat shock protein binding
C7I86_01260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7I86_01270	COG1216	Glycosyl transferase, family 2
C7I86_01270	COG0463	Glycosyl transferase, family 2
C7I86_01280	COG0077	Prephenate dehydratase
C7I86_01280	COG1605	Chorismate mutase
C7I86_01290	COG2203	Gaf domain
C7I86_01290	COG3706	GGDEF domain
C7I86_01290	COG5001	Diguanylate cyclase
C7I86_01290	COG4251	negative regulation of phosphorylation
C7I86_01305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C7I86_01335	COG0589	response to stress
C7I86_01340	COG2226	methyltransferase
C7I86_01355	COG0538	isocitrate dehydrogenase activity
C7I86_01360	COG4636	protein conserved in cyanobacteria
C7I86_01370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_01385	COG0762	integral membrane protein
C7I86_01390	COG1840	ABC-type Fe3 transport system, periplasmic component
C7I86_01395	COG0336	Belongs to the RNA methyltransferase TrmD family
C7I86_01400	COG0205	6-phosphofructokinase activity
C7I86_01405	COG1289	transmembrane transporter activity
C7I86_01410	COG1555	photosystem II stabilization
C7I86_01420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7I86_01425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7I86_01430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7I86_01455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7I86_01460	COG0277	FAD linked oxidase domain protein
C7I86_01480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7I86_01490	COG0408	coproporphyrinogen oxidase activity
C7I86_01495	COG5398	heme oxygenase
C7I86_01505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7I86_01525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7I86_01530	COG0672	)-iron permease
C7I86_01535	COG0592	DNA-directed DNA polymerase activity
C7I86_01540	COG0159	tryptophan synthase activity
C7I86_01555	COG0436	Aminotransferase
C7I86_01565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7I86_01580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7I86_01590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7I86_01595	COG0701	Predicted permease
C7I86_01615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7I86_01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7I86_01625	COG4636	protein conserved in cyanobacteria
C7I86_01630	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7I86_01650	COG3206	protein involved in exopolysaccharide biosynthesis
C7I86_01650	COG0489	protein tyrosine kinase activity
C7I86_01690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7I86_01735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7I86_01740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7I86_01745	COG1088	dTDP-glucose 4,6-dehydratase activity
C7I86_01750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_01775	COG1215	transferase activity, transferring glycosyl groups
C7I86_01785	COG1215	transferase activity, transferring glycosyl groups
C7I86_01790	COG0438	transferase activity, transferring glycosyl groups
C7I86_01815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_01840	COG0297	glycogen (starch) synthase activity
C7I86_01845	COG0438	transferase activity, transferring glycosyl groups
C7I86_01850	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_01860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_01895	COG0110	maltose O-acetyltransferase activity
C7I86_01910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_01920	COG3781	membrane
C7I86_01925	COG0045	succinate-CoA ligase (ADP-forming) activity
C7I86_01930	COG0861	Integral membrane protein TerC family
C7I86_01935	COG2268	Band 7 protein
C7I86_01940	COG0463	Glycosyl transferase, family 2
C7I86_01945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7I86_01950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7I86_01955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7I86_01960	COG0004	ammonium transporteR
C7I86_01965	COG0745	RESPONSE REGULATOR receiver
C7I86_01980	COG0737	Belongs to the 5'-nucleotidase family
C7I86_01990	COG0529	Catalyzes the synthesis of activated sulfate
C7I86_01995	COG0811	peptide transport
C7I86_02000	COG0848	biopolymer transport protein
C7I86_02005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7I86_02005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7I86_02010	COG0530	calcium, potassium:sodium antiporter activity
C7I86_02025	COG0745	RESPONSE REGULATOR receiver
C7I86_02030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7I86_02060	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7I86_02065	COG4251	negative regulation of phosphorylation
C7I86_02065	COG2203	Gaf domain
C7I86_02065	COG3706	GGDEF domain
C7I86_02065	COG5001	Diguanylate cyclase
C7I86_02075	COG3273	potassium ion transport
C7I86_02075	COG0471	metal ion transport
C7I86_02105	COG3854	ATPases associated with a variety of cellular activities
C7I86_02110	COG0352	thiamine-phosphate diphosphorylase activity
C7I86_02115	COG0434	BtpA family
C7I86_02140	COG0564	pseudouridine synthase activity
C7I86_02145	COG5001	Diguanylate cyclase
C7I86_02145	COG2203	Gaf domain
C7I86_02145	COG3706	GGDEF domain
C7I86_02145	COG4251	negative regulation of phosphorylation
C7I86_02155	COG0475	glutathione-regulated potassium exporter activity
C7I86_02190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7I86_02195	COG1733	regulation of RNA biosynthetic process
C7I86_02200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7I86_02240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C7I86_02255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_02265	COG1487	ribonuclease activity
C7I86_02285	COG2361	Protein of unknown function DUF86
C7I86_02300	COG0070	glutamate synthase
C7I86_02300	COG0067	glutamate synthase
C7I86_02300	COG0069	glutamate synthase activity
C7I86_02310	COG2133	pyrroloquinoline quinone binding
C7I86_02315	COG1797	cobyrinic acid a,c-diamide synthase activity
C7I86_02320	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C7I86_02325	COG1022	Amp-dependent synthetase and ligase
C7I86_02330	COG0784	Response regulator, receiver
C7I86_02345	COG2203	Gaf domain
C7I86_02345	COG0840	transmembrane signaling receptor activity
C7I86_02350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7I86_02355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7I86_02360	COG3706	GGDEF domain
C7I86_02360	COG4251	negative regulation of phosphorylation
C7I86_02360	COG2203	Gaf domain
C7I86_02360	COG5001	Diguanylate cyclase
C7I86_02365	COG0419	ATPase involved in DNA repair
C7I86_02370	COG0484	heat shock protein binding
C7I86_02375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7I86_02385	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7I86_02410	COG1429	ligase activity, forming nitrogen-metal bonds
C7I86_02425	COG3956	TIGRFAM MazG family protein
C7I86_02435	COG5002	protein histidine kinase activity
C7I86_02455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_02470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7I86_02475	COG1247	-acetyltransferase
C7I86_02480	COG0174	glutamine synthetase
C7I86_02490	COG5001	Diguanylate cyclase
C7I86_02490	COG2203	Gaf domain
C7I86_02490	COG3706	GGDEF domain
C7I86_02490	COG4251	negative regulation of phosphorylation
C7I86_02500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7I86_02505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7I86_02520	COG2310	stress, protein
C7I86_02525	COG0076	glutamate decarboxylase activity
C7I86_02540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_02545	COG0829	nickel cation binding
C7I86_02560	COG1045	serine acetyltransferase
C7I86_02575	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C7I86_02590	COG0271	Belongs to the BolA IbaG family
C7I86_02595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7I86_02600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7I86_02620	COG0804	urea catabolic process
C7I86_02635	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_02655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7I86_02660	COG1773	rubredoxin
C7I86_02665	COG4447	cellulose binding
C7I86_02690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7I86_02695	COG3385	transposase activity
C7I86_02715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7I86_02725	COG3228	Belongs to the MtfA family
C7I86_02760	COG1121	(ABC) transporter
C7I86_02765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7I86_02780	COG1702	phosphate starvation-inducible protein PhoH
C7I86_02795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_02815	COG0484	heat shock protein binding
C7I86_02820	COG0443	Heat shock 70 kDa protein
C7I86_02825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7I86_02865	COG3659	wide pore channel activity
C7I86_02875	COG2247	cell wall binding repeat
C7I86_02875	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7I86_02935	COG0768	penicillin binding
C7I86_02945	COG0247	lactate metabolic process
C7I86_02955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_02965	COG0583	DNA-binding transcription factor activity
C7I86_02975	COG0384	phenazine biosynthesis protein PhzF
C7I86_02985	COG2319	Wd-40 repeat
C7I86_02990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7I86_03015	COG0475	glutathione-regulated potassium exporter activity
C7I86_03015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7I86_03020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7I86_03040	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C7I86_03045	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C7I86_03060	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
C7I86_03065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7I86_03080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7I86_03085	COG0629	single-stranded DNA binding
C7I86_03100	COG0668	transmembrane transport
C7I86_03110	COG0745	RESPONSE REGULATOR receiver
C7I86_03115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_03115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C7I86_03120	COG3937	granule-associated protein
C7I86_03135	COG2226	methyltransferase
C7I86_03145	COG0681	Belongs to the peptidase S26 family
C7I86_03155	COG1271	oxidase subunit
C7I86_03160	COG1294	oxidase, subunit
C7I86_03165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7I86_03170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7I86_03175	COG0412	Dienelactone hydrolase
C7I86_03225	COG2203	Gaf domain
C7I86_03225	COG0840	transmembrane signaling receptor activity
C7I86_03240	COG0784	Response regulator, receiver
C7I86_03245	COG0557	exoribonuclease II activity
C7I86_03255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_03270	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7I86_03280	COG5002	protein histidine kinase activity
C7I86_03285	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7I86_03295	COG1309	transcriptional regulator
C7I86_03320	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C7I86_03330	COG2385	sporulation resulting in formation of a cellular spore
C7I86_03340	COG3411	Ferredoxin
C7I86_03345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7I86_03370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7I86_03375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7I86_03380	COG0237	dephospho-CoA kinase activity
C7I86_03385	COG0237	dephospho-CoA kinase activity
C7I86_03415	COG0515	serine threonine protein kinase
C7I86_03420	COG0515	serine threonine protein kinase
C7I86_03430	COG2988	succinylglutamate desuccinylase activity
C7I86_03435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7I86_03445	COG0739	heme binding
C7I86_03450	COG0587	DNA-directed DNA polymerase activity
C7I86_03465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7I86_03495	COG1006	Multisubunit Na H antiporter MnhC subunit
C7I86_03570	COG1132	(ABC) transporter
C7I86_03575	COG3063	Type IV pilus biogenesis stability protein PilW
C7I86_03580	COG2217	Heavy metal translocating P-type atpase
C7I86_03585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7I86_03590	COG0745	RESPONSE REGULATOR receiver
C7I86_03600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7I86_03605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7I86_03615	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7I86_03645	COG0557	exoribonuclease II activity
C7I86_03655	COG2208	phosphoserine phosphatase activity
C7I86_03665	COG0165	Argininosuccinate lyase
C7I86_03670	COG2816	NAD+ diphosphatase activity
C7I86_03685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7I86_03690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7I86_03695	COG1845	cytochrome c oxidase, subunit III
C7I86_03700	COG3118	belongs to the thioredoxin family
C7I86_03710	COG1116	anion transmembrane transporter activity
C7I86_03715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7I86_03730	COG0375	protein maturation
C7I86_03735	COG0010	Belongs to the arginase family
C7I86_03745	COG3706	GGDEF domain
C7I86_03750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_03760	COG0495	leucyl-tRNA aminoacylation
C7I86_03765	COG0786	glutamate:sodium symporter activity
C7I86_03775	COG2205	protein histidine kinase activity
C7I86_03785	COG1132	(ABC) transporter
C7I86_03805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7I86_03810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7I86_03815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7I86_03840	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7I86_03845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7I86_03855	COG0254	rRNA binding
C7I86_03860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7I86_03865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7I86_03870	COG0101	tRNA pseudouridine synthase activity
C7I86_03875	COG0203	ribosomal protein L17
C7I86_03880	COG0202	RNA polymerase activity
C7I86_03885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7I86_03890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7I86_03895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7I86_03900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7I86_03905	COG0563	adenylate kinase activity
C7I86_03910	COG0201	protein transport
C7I86_03915	COG0200	Binds to the 23S rRNA
C7I86_03920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7I86_03925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7I86_03930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7I86_03935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7I86_03940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7I86_03945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7I86_03950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7I86_03955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7I86_03960	COG0255	Belongs to the universal ribosomal protein uL29 family
C7I86_03965	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7I86_03970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7I86_03975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7I86_03980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7I86_03985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7I86_03990	COG0089	rRNA binding
C7I86_03995	COG0088	Forms part of the polypeptide exit tunnel
C7I86_04000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7I86_04005	COG0783	Belongs to the Dps family
C7I86_04025	COG2010	Cytochrome c
C7I86_04035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7I86_04040	COG0830	nickel cation binding
C7I86_04050	COG1131	(ABC) transporter
C7I86_04065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7I86_04070	COG0085	RNA polymerase activity
C7I86_04075	COG0084	hydrolase, TatD family'
C7I86_04080	COG0268	Binds directly to 16S ribosomal RNA
C7I86_04085	COG5002	protein histidine kinase activity
C7I86_04095	COG0210	DNA helicase
C7I86_04095	COG0210	DNA helicase
C7I86_04100	COG1196	nuclear chromosome segregation
C7I86_04105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7I86_04125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7I86_04125	COG0758	DNA mediated transformation
C7I86_04130	COG0393	Putative heavy-metal-binding
C7I86_04140	COG0450	alkyl hydroperoxide reductase
C7I86_04145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7I86_04150	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7I86_04160	COG1175	transmembrane transport
C7I86_04170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7I86_04195	COG3347	Dehydrogenase
C7I86_04195	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_04215	COG2203	Gaf domain
C7I86_04215	COG3706	GGDEF domain
C7I86_04215	COG4251	negative regulation of phosphorylation
C7I86_04215	COG5001	Diguanylate cyclase
C7I86_04220	COG0745	RESPONSE REGULATOR receiver
C7I86_04225	COG0784	Response regulator, receiver
C7I86_04235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7I86_04240	COG2239	Acts as a magnesium transporter
C7I86_04270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7I86_04275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7I86_04280	COG1799	cell septum assembly
C7I86_04285	COG0662	Cupin 2, conserved barrel domain protein
C7I86_04285	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C7I86_04300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7I86_04305	COG0459	protein refolding
C7I86_04325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7I86_04330	COG0222	ribosome binding
C7I86_04335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7I86_04340	COG0081	regulation of translation
C7I86_04345	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7I86_04350	COG0250	Participates in transcription elongation, termination and antitermination
C7I86_04355	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7I86_04365	COG0335	large ribosomal subunit rRNA binding
C7I86_04395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7I86_04405	COG3243	poly(R)-hydroxyalkanoic acid synthase
C7I86_04415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C7I86_04425	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_04430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7I86_04440	COG2885	chlorophyll binding
C7I86_04445	COG2885	chlorophyll binding
C7I86_04455	COG1132	(ABC) transporter
C7I86_04465	COG0438	transferase activity, transferring glycosyl groups
C7I86_04475	COG0745	RESPONSE REGULATOR receiver
C7I86_04480	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7I86_04480	COG0022	dehydrogenase e1 component
C7I86_04485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_04490	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_04495	COG1929	Belongs to the glycerate kinase type-1 family
C7I86_04500	COG3659	wide pore channel activity
C7I86_04505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7I86_04510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7I86_04515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7I86_04555	COG0776	regulation of translation
C7I86_04570	COG0514	ATP-dependent DNA helicase (RecQ)
C7I86_04580	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
C7I86_04585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7I86_04595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7I86_04645	COG0438	transferase activity, transferring glycosyl groups
C7I86_04650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7I86_04655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C7I86_04660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_04675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7I86_04680	COG0242	peptide deformylase activity
C7I86_04690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7I86_04720	COG0243	molybdopterin cofactor binding
C7I86_04725	COG1116	anion transmembrane transporter activity
C7I86_04730	COG1116	anion transmembrane transporter activity
C7I86_04730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_04735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7I86_04740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_04755	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7I86_04760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7I86_04770	COG0793	Belongs to the peptidase S41A family
C7I86_04780	COG0275	rRNA processing
C7I86_04790	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C7I86_04815	COG1090	epimerase
C7I86_04825	COG0515	serine threonine protein kinase
C7I86_04835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7I86_04840	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7I86_04845	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7I86_04850	COG0659	secondary active sulfate transmembrane transporter activity
C7I86_04855	COG0589	response to stress
C7I86_04860	COG1233	COG1233 Phytoene dehydrogenase and related
C7I86_04875	COG1053	succinate dehydrogenase
C7I86_04880	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
C7I86_04885	COG0537	adenosine 5'-monophosphoramidase activity
C7I86_04915	COG0402	S-adenosylhomocysteine deaminase activity
C7I86_04930	COG2267	carboxylic ester hydrolase activity
C7I86_04940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7I86_04945	COG0189	ligase activity
C7I86_04955	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7I86_04960	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7I86_04985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C7I86_04990	COG0312	modulator of DNA gyrase
C7I86_05010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7I86_05020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7I86_05020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7I86_05035	COG2140	Oxalate decarboxylase
C7I86_05040	COG0058	SHG alpha-glucan phosphorylase activity
C7I86_05070	COG0515	serine threonine protein kinase
C7I86_05090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7I86_05090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7I86_05095	COG2205	protein histidine kinase activity
C7I86_05095	COG3437	response regulator, receiver
C7I86_05095	COG3850	Histidine kinase
C7I86_05095	COG4999	Histidine kinase
C7I86_05130	COG0546	phosphoglycolate phosphatase activity
C7I86_05135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7I86_05140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7I86_05155	COG0501	Belongs to the peptidase M48B family
C7I86_05160	COG0539	negative regulation of cytoplasmic translation
C7I86_05170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7I86_05175	COG1132	(ABC) transporter
C7I86_05180	COG0469	pyruvate kinase activity
C7I86_05200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7I86_05205	COG1268	BioY protein
C7I86_05210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7I86_05230	COG3659	wide pore channel activity
C7I86_05245	COG0058	SHG alpha-glucan phosphorylase activity
C7I86_05255	COG0575	Belongs to the CDS family
C7I86_05280	COG1970	mechanosensitive ion channel activity
C7I86_05285	COG0632	four-way junction helicase activity
C7I86_05290	COG1836	PFAM Integral membrane protein DUF92
C7I86_05295	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7I86_05300	COG0724	RNA recognition motif
C7I86_05305	COG0154	amidase activity
C7I86_05310	COG0739	heme binding
C7I86_05315	COG0509	glycine decarboxylation via glycine cleavage system
C7I86_05330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7I86_05350	COG1316	TRANSCRIPTIONal
C7I86_05365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7I86_05380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7I86_05385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7I86_05395	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_05415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_05430	COG0322	excinuclease ABC activity
C7I86_05455	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7I86_05465	COG3258	Cytochrome c
C7I86_05470	COG0723	plastoquinol--plastocyanin reductase activity
C7I86_05495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7I86_05520	COG2319	Wd-40 repeat
C7I86_05525	COG2319	Wd-40 repeat
C7I86_05545	COG1082	Xylose isomerase domain protein TIM barrel
C7I86_05560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7I86_05585	COG1366	Belongs to the anti-sigma-factor antagonist family
C7I86_05600	COG2208	phosphoserine phosphatase activity
C7I86_05600	COG2770	Histidine kinase
C7I86_05630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7I86_05635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7I86_05675	COG1741	Belongs to the pirin family
C7I86_05685	COG1193	negative regulation of DNA recombination
C7I86_05690	COG0631	protein serine/threonine phosphatase activity
C7I86_05695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_05705	COG3937	granule-associated protein
C7I86_05720	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7I86_05725	COG3932	Exopolysaccharide synthesis, ExoD
C7I86_05730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7I86_05740	COG0360	Binds together with S18 to 16S ribosomal RNA
C7I86_05745	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7I86_05750	COG1413	lyase activity
C7I86_05755	COG0641	radical SAM
C7I86_05790	COG0083	homoserine kinase activity
C7I86_05800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7I86_05805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_05815	COG0196	riboflavin kinase activity
C7I86_05835	COG0180	Tryptophanyl-tRNA synthetase
C7I86_05840	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7I86_05845	COG0799	negative regulation of ribosome biogenesis
C7I86_05855	COG0181	hydroxymethylbilane synthase activity
C7I86_05860	COG0427	acetyl-CoA hydrolase
C7I86_05865	COG0857	belongs to the CobB CobQ family
C7I86_05865	COG0280	phosphate acetyltransferase
C7I86_05875	COG1489	DNA binding
C7I86_05885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_05895	COG0602	queuosine metabolic process
C7I86_05900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7I86_05905	COG0612	Peptidase, M16
C7I86_05910	COG0612	Peptidase, M16
C7I86_05920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7I86_05935	COG1372	Participates in initiation and elongation during chromosome replication
C7I86_05935	COG0187	DNA topoisomerase II activity
C7I86_05950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7I86_05950	COG0646	methionine synthase
C7I86_05960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7I86_05985	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_05995	COG2197	response regulator
C7I86_06000	COG3706	GGDEF domain
C7I86_06000	COG4251	negative regulation of phosphorylation
C7I86_06000	COG5001	Diguanylate cyclase
C7I86_06000	COG2203	Gaf domain
C7I86_06010	COG0616	signal peptide processing
C7I86_06020	COG0596	Alpha beta hydrolase
C7I86_06025	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7I86_06035	COG0747	negative chemotaxis
C7I86_06045	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7I86_06085	COG4968	Prepilin-type N-terminal cleavage methylation domain
C7I86_06090	COG4968	Prepilin-type N-terminal cleavage methylation domain
C7I86_06115	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_06120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_06125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7I86_06135	COG2199	diguanylate cyclase activity
C7I86_06140	COG0750	zinc metalloprotease
C7I86_06145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7I86_06155	COG0590	tRNA wobble adenosine to inosine editing
C7I86_06165	COG0415	Belongs to the DNA photolyase family
C7I86_06175	COG3429	Glucose-6-phosphate dehydrogenase subunit
C7I86_06175	COG3409	Peptidoglycan-binding domain 1 protein
C7I86_06185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7I86_06190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7I86_06205	COG1122	ATPase activity
C7I86_06210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7I86_06220	COG0678	peroxiredoxin activity
C7I86_06260	COG1252	NADH dehydrogenase
C7I86_06270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7I86_06295	COG0415	Belongs to the DNA photolyase family
C7I86_06310	COG1595	DNA-templated transcription, initiation
C7I86_06350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7I86_06360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7I86_06365	COG3339	Conserved Protein
C7I86_06375	COG0312	modulator of DNA gyrase
C7I86_06380	COG0482	sulfurtransferase activity
C7I86_06395	COG0488	(ABC) transporter
C7I86_06400	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C7I86_06410	COG0284	orotidine-5'-phosphate decarboxylase activity
C7I86_06460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7I86_06470	COG0697	spore germination
C7I86_06505	COG0583	DNA-binding transcription factor activity
C7I86_06525	COG2814	Major facilitator Superfamily
C7I86_06530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7I86_06535	COG0573	inorganic phosphate transmembrane transporter activity
C7I86_06540	COG0581	inorganic phosphate transmembrane transporter activity
C7I86_06545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7I86_06550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7I86_06555	COG2154	pterin-4-alpha-carbinolamine dehydratase
C7I86_06580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7I86_06580	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7I86_06585	COG1562	ergosterol biosynthetic process
C7I86_06590	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C7I86_06595	COG0831	urea catabolic process
C7I86_06605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7I86_06625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7I86_06630	COG0730	response to heat
C7I86_06640	COG2188	Transcriptional regulator
C7I86_06655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7I86_06660	COG0640	Transcriptional regulator
C7I86_06665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7I86_06670	COG1754	DNA topoisomerase type I activity
C7I86_06670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7I86_06710	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
C7I86_06740	COG2264	protein methyltransferase activity
C7I86_06745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7I86_06760	COG0386	Belongs to the glutathione peroxidase family
C7I86_06765	COG0183	Belongs to the thiolase family
C7I86_06770	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_06780	COG4999	Histidine kinase
C7I86_06780	COG3850	Histidine kinase
C7I86_06780	COG3437	response regulator, receiver
C7I86_06780	COG2205	protein histidine kinase activity
C7I86_06800	COG4242	Belongs to the peptidase S51 family
C7I86_06805	COG0189	ligase activity
C7I86_06805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7I86_06840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_06845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_06855	COG0285	dihydrofolate synthase activity
C7I86_06870	COG4636	protein conserved in cyanobacteria
C7I86_06890	COG1606	tRNA processing
C7I86_06900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7I86_06910	COG2045	Belongs to the ComB family
C7I86_06915	COG0778	Nitroreductase
C7I86_06920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7I86_06930	COG0516	GMP reductase activity
C7I86_06935	COG0395	ABC-type sugar transport system, permease component
C7I86_06940	COG3268	Saccharopine dehydrogenase
C7I86_06955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7I86_06960	COG1121	(ABC) transporter
C7I86_06965	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7I86_06975	COG4251	negative regulation of phosphorylation
C7I86_06980	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7I86_06990	COG0583	DNA-binding transcription factor activity
C7I86_06995	COG0025	NhaP-type Na H and K H
C7I86_07000	COG2197	response regulator
C7I86_07005	COG5002	protein histidine kinase activity
C7I86_07010	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C7I86_07015	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C7I86_07025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C7I86_07030	COG2205	protein histidine kinase activity
C7I86_07040	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7I86_07060	COG2385	sporulation resulting in formation of a cellular spore
C7I86_07065	COG0649	NAD binding
C7I86_07080	COG0429	hydrolase of the alpha beta-hydrolase fold
C7I86_07090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7I86_07095	COG3536	Protein conserved in bacteria
C7I86_07100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7I86_07105	COG0716	FMN binding
C7I86_07115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7I86_07120	COG0012	GTP binding
C7I86_07125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_07180	COG3842	ATPase activity
C7I86_07190	COG1840	ABC-type Fe3 transport system, periplasmic component
C7I86_07195	COG0222	ribosome binding
C7I86_07205	COG2066	Belongs to the glutaminase family
C7I86_07225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7I86_07240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7I86_07245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C7I86_07250	COG1333	cytochrome c biogenesis protein
C7I86_07260	COG1657	PFAM Prenyltransferase squalene oxidase
C7I86_07305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7I86_07315	COG1494	fructose-1,6-bisphosphatase
C7I86_07325	COG2346	COG2346, Truncated hemoglobins
C7I86_07330	COG2205	protein histidine kinase activity
C7I86_07330	COG4999	Histidine kinase
C7I86_07330	COG3437	response regulator, receiver
C7I86_07330	COG3850	Histidine kinase
C7I86_07340	COG3437	response regulator, receiver
C7I86_07345	COG1917	Cupin 2, conserved barrel domain protein
C7I86_07350	COG0552	protein localization to endoplasmic reticulum
C7I86_07360	COG0784	Response regulator, receiver
C7I86_07360	COG5002	protein histidine kinase activity
C7I86_07360	COG2205	protein histidine kinase activity
C7I86_07365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7I86_07375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7I86_07395	COG0667	Aldo Keto reductase
C7I86_07400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7I86_07410	COG0442	prolyl-tRNA aminoacylation
C7I86_07420	COG4372	Transposase
C7I86_07425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_07450	COG0438	transferase activity, transferring glycosyl groups
C7I86_07455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7I86_07460	COG0416	fatty acid biosynthetic process
C7I86_07465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7I86_07485	COG0347	Belongs to the P(II) protein family
C7I86_07490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7I86_07515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7I86_07520	COG0473	3-isopropylmalate dehydrogenase activity
C7I86_07530	COG1575	Belongs to the MenA family. Type 1 subfamily
C7I86_07540	COG0656	L-ascorbic acid biosynthetic process
C7I86_07580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7I86_07595	COG2161	toxin-antitoxin pair type II binding
C7I86_07600	COG4115	mRNA cleavage
C7I86_07635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7I86_07635	COG0517	IMP dehydrogenase activity
C7I86_07645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7I86_07655	COG1215	transferase activity, transferring glycosyl groups
C7I86_07680	COG1216	Glycosyl transferase, family 2
C7I86_07685	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C7I86_07700	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_07725	COG0463	Glycosyl transferase, family 2
C7I86_07730	COG0113	porphobilinogen synthase activity
C7I86_07740	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7I86_07745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7I86_07775	COG0312	modulator of DNA gyrase
C7I86_07780	COG2890	protein-(glutamine-N5) methyltransferase activity
C7I86_07785	COG2205	protein histidine kinase activity
C7I86_07800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7I86_07805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C7I86_07830	COG0438	transferase activity, transferring glycosyl groups
C7I86_07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7I86_07840	COG2205	protein histidine kinase activity
C7I86_07845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7I86_07850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7I86_07855	COG0612	Peptidase, M16
C7I86_07860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7I86_07865	COG3259	Nickel-dependent hydrogenase
C7I86_07880	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
C7I86_07885	COG1034	ATP synthesis coupled electron transport
C7I86_07930	COG0702	epimerase
C7I86_07965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7I86_07970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7I86_07985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7I86_07995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7I86_08000	COG0673	inositol 2-dehydrogenase activity
C7I86_08015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7I86_08020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7I86_08055	COG0095	Lipoate-protein ligase
C7I86_08075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C7I86_08085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7I86_08095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7I86_08100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7I86_08105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_08110	COG0457	Tetratricopeptide repeat
C7I86_08115	COG1160	GTP binding
C7I86_08135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7I86_08150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7I86_08155	COG0052	Belongs to the universal ribosomal protein uS2 family
C7I86_08165	COG0387	Pfam Sodium calcium exchanger
C7I86_08170	COG0717	Belongs to the dCTP deaminase family
C7I86_08200	COG3385	transposase activity
C7I86_08205	COG1253	flavin adenine dinucleotide binding
C7I86_08215	COG3046	protein related to deoxyribodipyrimidine photolyase
C7I86_08220	COG0517	IMP dehydrogenase activity
C7I86_08220	COG0516	GMP reductase activity
C7I86_08230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7I86_08245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7I86_08245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7I86_08250	COG0288	reversible hydration of carbon dioxide
C7I86_08255	COG1045	serine acetyltransferase
C7I86_08265	COG0166	Belongs to the GPI family
C7I86_08270	COG3239	Fatty acid desaturase
C7I86_08275	COG1672	PFAM Archaeal ATPase
C7I86_08280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7I86_08285	COG2010	Cytochrome c
C7I86_08290	COG0359	binds to the 23S rRNA
C7I86_08300	COG1032	radical SAM domain protein
C7I86_08330	COG0298	carbon dioxide binding
C7I86_08335	COG0109	protoheme IX farnesyltransferase activity
C7I86_08340	COG1612	heme a metabolic process
C7I86_08365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C7I86_08370	COG1716	ATPase activity
C7I86_08370	COG5001	Diguanylate cyclase
C7I86_08375	COG3631	Ketosteroid isomerase-related protein
C7I86_08385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7I86_08385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7I86_08395	COG0107	imidazoleglycerol-phosphate synthase activity
C7I86_08420	COG2202	Pas domain
C7I86_08420	COG2205	protein histidine kinase activity
C7I86_08435	COG4783	chaperone-mediated protein folding
C7I86_08440	COG3850	Histidine kinase
C7I86_08440	COG4999	Histidine kinase
C7I86_08440	COG2205	protein histidine kinase activity
C7I86_08440	COG3437	response regulator, receiver
C7I86_08450	COG4956	integral membrane protein (PIN domain superfamily)
C7I86_08465	COG1160	GTP binding
C7I86_08475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7I86_08490	COG0432	Pfam Uncharacterised protein family UPF0047
C7I86_08495	COG2197	response regulator
C7I86_08500	COG3842	ATPase activity
C7I86_08510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7I86_08515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7I86_08525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7I86_08530	COG5398	heme oxygenase
C7I86_08535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7I86_08545	COG1316	TRANSCRIPTIONal
C7I86_08555	COG3706	GGDEF domain
C7I86_08555	COG0745	RESPONSE REGULATOR receiver
C7I86_08560	COG2208	phosphoserine phosphatase activity
C7I86_08560	COG2770	Histidine kinase
C7I86_08565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7I86_08575	COG0539	negative regulation of cytoplasmic translation
C7I86_08580	COG0358	DNA primase activity
C7I86_08590	COG0009	L-threonylcarbamoyladenylate synthase
C7I86_08610	COG0589	response to stress
C7I86_08635	COG2082	Precorrin-8x methylmutase
C7I86_08645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7I86_08650	COG0594	ribonuclease P activity
C7I86_08660	COG0706	membrane insertase activity
C7I86_08670	COG0484	heat shock protein binding
C7I86_08675	COG0483	inositol monophosphate 1-phosphatase activity
C7I86_08680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7I86_08695	COG0791	NLP P60 protein
C7I86_08710	COG0540	Belongs to the ATCase OTCase family
C7I86_08725	COG1215	transferase activity, transferring glycosyl groups
C7I86_08735	COG0300	oxidoreductase activity
C7I86_08735	COG3000	fatty acid hydroxylase
C7I86_08745	COG2211	Major facilitator Superfamily
C7I86_08760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_08775	COG0723	plastoquinol--plastocyanin reductase activity
C7I86_08785	COG2274	protein secretion by the type I secretion system
C7I86_08795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7I86_08800	COG2192	nodulation
C7I86_08810	COG0772	Belongs to the SEDS family
C7I86_08815	COG0405	Gamma-glutamyltransferase
C7I86_08830	COG3659	wide pore channel activity
C7I86_08870	COG0037	tRNA processing
C7I86_08875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7I86_08880	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_08885	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_08890	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_08945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_08960	COG0628	permease
C7I86_08975	COG0066	3-isopropylmalate dehydratase activity
C7I86_08980	COG0504	CTP synthase activity
C7I86_08995	COG2204	response regulator
C7I86_09005	COG0259	pyridoxamine-phosphate oxidase activity
C7I86_09025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7I86_09035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7I86_09040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7I86_09045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7I86_09045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7I86_09050	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7I86_09060	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7I86_09065	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_09080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C7I86_09090	COG0051	transcription antitermination factor activity, RNA binding
C7I86_09095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7I86_09100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7I86_09105	COG0049	tRNA binding
C7I86_09110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7I86_09120	COG0151	Belongs to the GarS family
C7I86_09130	COG0698	ribose 5-phosphate isomerase
C7I86_09160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7I86_09165	COG2046	Belongs to the sulfate adenylyltransferase family
C7I86_09170	COG0297	glycogen (starch) synthase activity
C7I86_09185	COG0644	oxidoreductase
C7I86_09190	COG0371	Dehydrogenase
C7I86_09205	COG2119	membrane
C7I86_09210	COG0386	Belongs to the glutathione peroxidase family
C7I86_09225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7I86_09245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7I86_09250	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C7I86_09260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7I86_09265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7I86_09275	COG0375	protein maturation
C7I86_09290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7I86_09295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7I86_09300	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C7I86_09305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7I86_09310	COG1134	teichoic acid transport
C7I86_09345	COG1012	belongs to the aldehyde dehydrogenase family
C7I86_09360	COG3385	transposase activity
C7I86_09400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7I86_09410	COG1304	FMN binding
C7I86_09415	COG0745	RESPONSE REGULATOR receiver
C7I86_09425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7I86_09435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7I86_09435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_09440	COG2203	Gaf domain
C7I86_09440	COG5001	Diguanylate cyclase
C7I86_09440	COG4251	negative regulation of phosphorylation
C7I86_09440	COG3706	GGDEF domain
C7I86_09445	COG0784	Response regulator, receiver
C7I86_09455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7I86_09455	COG0072	phenylalanine-tRNA ligase activity
C7I86_09460	COG0515	serine threonine protein kinase
C7I86_09460	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_09465	COG2197	response regulator
C7I86_09470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C7I86_09485	COG0157	Belongs to the NadC ModD family
C7I86_09500	COG2082	Precorrin-8x methylmutase
C7I86_09505	COG0612	Peptidase, M16
C7I86_09510	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7I86_09520	COG0656	L-ascorbic acid biosynthetic process
C7I86_09525	COG3588	fructose-bisphosphate aldolase
C7I86_09535	COG0798	PFAM Bile acid sodium symporter
C7I86_09540	COG0431	NADPH-dependent FMN reductase
C7I86_09545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7I86_09565	COG0488	(ABC) transporter
C7I86_09575	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7I86_09595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7I86_09600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C7I86_09605	COG0561	phosphatase activity
C7I86_09610	COG1366	Belongs to the anti-sigma-factor antagonist family
C7I86_09615	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7I86_09620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7I86_09630	COG0215	cysteine-tRNA ligase activity
C7I86_09635	COG0424	maF-like protein
C7I86_09650	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C7I86_09655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7I86_09660	COG0463	Glycosyl transferase, family 2
C7I86_09665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7I86_09680	COG1472	Belongs to the glycosyl hydrolase 3 family
C7I86_09685	COG2816	NAD+ diphosphatase activity
C7I86_09690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7I86_09695	COG1280	lysine exporter protein (LysE YggA)
C7I86_09710	COG0564	pseudouridine synthase activity
C7I86_09720	COG0438	transferase activity, transferring glycosyl groups
C7I86_09745	COG3385	transposase activity
C7I86_09765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7I86_09780	COG0438	transferase activity, transferring glycosyl groups
C7I86_09790	COG0500	methyltransferase
C7I86_09795	COG0542	response to heat
C7I86_09805	COG0572	uridine kinase
C7I86_09810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7I86_09815	COG0561	phosphatase activity
C7I86_09830	COG0571	ribonuclease III activity
C7I86_09835	COG0390	transport system, permease component
C7I86_09840	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C7I86_09845	COG2161	toxin-antitoxin pair type II binding
C7I86_09860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7I86_09865	COG0426	domain, Protein
C7I86_09865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_09870	COG0497	DNA recombination
C7I86_09880	COG3751	2OG-Fe(II) oxygenase superfamily
C7I86_09910	COG2161	toxin-antitoxin pair type II binding
C7I86_09915	COG4115	mRNA cleavage
C7I86_09940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7I86_09945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7I86_09960	COG1446	asparaginase
C7I86_09965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7I86_09975	COG0832	Belongs to the urease beta subunit family
C7I86_09985	COG2226	methyltransferase
C7I86_10000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7I86_10010	COG0025	NhaP-type Na H and K H
C7I86_10020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7I86_10030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7I86_10070	COG3239	Fatty acid desaturase
C7I86_10080	COG1950	PFAM Membrane protein of
C7I86_10095	COG1253	flavin adenine dinucleotide binding
C7I86_10100	COG0228	four-way junction DNA binding
C7I86_10120	COG2010	Cytochrome c
C7I86_10135	COG0802	atpase or kinase
C7I86_10140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7I86_10140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7I86_10170	COG0126	phosphoglycerate kinase activity
C7I86_10175	COG0583	DNA-binding transcription factor activity
C7I86_10180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7I86_10215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7I86_10230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7I86_10235	COG0347	Belongs to the P(II) protein family
C7I86_10250	COG0135	phosphoribosylanthranilate isomerase activity
C7I86_10255	COG0697	spore germination
C7I86_10275	COG0418	dihydroorotase activity
C7I86_10280	COG2226	methyltransferase
C7I86_10295	COG1672	PFAM Archaeal ATPase
C7I86_10295	COG2319	Wd-40 repeat
C7I86_10335	COG2815	serine threonine protein kinase
C7I86_10335	COG0515	serine threonine protein kinase
C7I86_10360	COG0233	cytoplasmic translational termination
C7I86_10365	COG0528	UMP kinase activity
C7I86_10370	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_10380	COG0542	response to heat
C7I86_10410	COG0740	serine-type endopeptidase activity
C7I86_10415	COG0740	serine-type endopeptidase activity
C7I86_10420	COG0006	proline dipeptidase activity
C7I86_10425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7I86_10445	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
C7I86_10455	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C7I86_10495	COG2165	general secretion pathway protein
C7I86_10505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7I86_10545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7I86_10565	COG0105	UTP biosynthetic process
C7I86_10590	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7I86_10595	COG2937	Belongs to the GPAT DAPAT family
C7I86_10605	COG0501	Belongs to the peptidase M48B family
C7I86_10625	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7I86_10635	COG0463	Glycosyl transferase, family 2
C7I86_10645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7I86_10660	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7I86_10670	COG2217	Heavy metal translocating P-type atpase
C7I86_10680	COG0217	transcriptional regulatory protein
C7I86_10685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C7I86_10690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7I86_10695	COG0739	heme binding
C7I86_10700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7I86_10705	COG0321	lipoyl(octanoyl) transferase activity
C7I86_10720	COG0297	glycogen (starch) synthase activity
C7I86_10735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_10740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7I86_10745	COG0643	Histidine kinase
C7I86_10745	COG2198	Histidine kinase
C7I86_10780	COG1178	ABC-type Fe3 transport system permease component
C7I86_10785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7I86_10810	COG2197	response regulator
C7I86_10820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_10845	COG0237	dephospho-CoA kinase activity
C7I86_10845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_10895	COG0516	GMP reductase activity
C7I86_10895	COG0517	IMP dehydrogenase activity
C7I86_10905	COG1937	Protein conserved in bacteria
C7I86_10920	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C7I86_10940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7I86_10945	COG0443	Heat shock 70 kDa protein
C7I86_10950	COG0484	heat shock protein binding
C7I86_10965	COG1587	Uroporphyrinogen-III synthase
C7I86_10970	COG2319	Wd-40 repeat
C7I86_10990	COG3385	transposase activity
C7I86_11000	COG1381	Involved in DNA repair and RecF pathway recombination
C7I86_11020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7I86_11040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7I86_11045	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7I86_11050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7I86_11055	COG5001	Diguanylate cyclase
C7I86_11065	COG1187	pseudouridine synthase activity
C7I86_11070	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7I86_11100	COG1012	belongs to the aldehyde dehydrogenase family
C7I86_11105	COG5002	protein histidine kinase activity
C7I86_11110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7I86_11115	COG2308	Evidence 4 Homologs of previously reported genes of
C7I86_11145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7I86_11155	COG0346	lactoylglutathione lyase activity
C7I86_11165	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_11170	COG0742	ribosomal rna small subunit methyltransferase
C7I86_11175	COG0438	transferase activity, transferring glycosyl groups
C7I86_11185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7I86_11205	COG1104	cysteine desulfurase activity
C7I86_11210	COG1040	competence protein
C7I86_11215	COG1376	ErfK ybiS ycfS ynhG family protein
C7I86_11230	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
C7I86_11240	COG3659	wide pore channel activity
C7I86_11245	COG0477	Major facilitator Superfamily
C7I86_11250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7I86_11255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7I86_11260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7I86_11265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7I86_11270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7I86_11275	COG2003	Belongs to the UPF0758 family
C7I86_11310	COG1131	(ABC) transporter
C7I86_11320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7I86_11330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7I86_11340	COG0450	alkyl hydroperoxide reductase
C7I86_11345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7I86_11355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7I86_11365	COG1231	oxidoreductase activity
C7I86_11370	COG2205	protein histidine kinase activity
C7I86_11380	COG0149	triose-phosphate isomerase activity
C7I86_11385	COG0628	permease
C7I86_11400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7I86_11405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7I86_11420	COG0571	ribonuclease III activity
C7I86_11425	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C7I86_11450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7I86_11495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_11500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7I86_11535	COG0601	transmembrane transport
C7I86_11540	COG0124	histidyl-tRNA synthetase
C7I86_11585	COG0542	response to heat
C7I86_11590	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7I86_11595	COG0191	fructose-bisphosphate aldolase activity
C7I86_11600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7I86_11620	COG0793	Belongs to the peptidase S41A family
C7I86_11625	COG1850	ribulose-bisphosphate carboxylase activity
C7I86_11635	COG4451	ribulose bisphosphate carboxylase, small
C7I86_11645	COG1285	pathogenesis
C7I86_11655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7I86_11660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7I86_11670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7I86_11675	COG0114	fumarate hydratase activity
C7I86_11705	COG0436	Aminotransferase
C7I86_11710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_11715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7I86_11720	COG0616	signal peptide processing
C7I86_11725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7I86_11740	COG0519	Catalyzes the synthesis of GMP from XMP
C7I86_11740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7I86_11750	COG1968	undecaprenyl-diphosphatase activity
C7I86_11770	COG5322	oxidoreductase activity
C7I86_11775	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7I86_11785	COG0751	glycine-tRNA ligase activity
C7I86_11800	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7I86_11805	COG5002	protein histidine kinase activity
C7I86_11810	COG0445	tRNA wobble uridine modification
C7I86_11825	COG3794	PFAM blue (type 1) copper domain protein
C7I86_11840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_11845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7I86_11850	COG0805	protein transport
C7I86_11855	COG2084	Dehydrogenase
C7I86_11870	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7I86_11880	COG0586	Pfam SNARE associated Golgi protein
C7I86_11885	COG3118	belongs to the thioredoxin family
C7I86_11890	COG3751	2OG-Fe(II) oxygenase superfamily
C7I86_11895	COG0459	protein refolding
C7I86_11900	COG1131	(ABC) transporter
C7I86_11925	COG4399	Belongs to the UPF0754 family
C7I86_11930	COG0824	Thioesterase
C7I86_11935	COG4948	Mandelate Racemase Muconate Lactonizing
C7I86_11940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7I86_11945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7I86_11950	COG0511	ligase activity, forming carbon-carbon bonds
C7I86_11980	COG0277	FAD linked oxidase domain protein
C7I86_12010	COG0436	Aminotransferase
C7I86_12015	COG0372	Belongs to the citrate synthase family
C7I86_12020	COG2062	phosphohistidine phosphatase, SixA
C7I86_12025	COG0596	Alpha beta hydrolase
C7I86_12040	COG1234	tRNA 3'-trailer cleavage
C7I86_12055	COG0788	formyltetrahydrofolate deformylase activity
C7I86_12075	COG0625	glutathione transferase activity
C7I86_12085	COG0440	acetolactate synthase activity
C7I86_12095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7I86_12100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7I86_12110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7I86_12115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7I86_12125	COG0628	permease
C7I86_12160	COG0628	permease
C7I86_12165	COG0443	Heat shock 70 kDa protein
C7I86_12170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7I86_12175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7I86_12180	COG0116	Belongs to the methyltransferase superfamily
C7I86_12190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7I86_12190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7I86_12200	COG0612	Peptidase, M16
C7I86_12205	COG0489	protein tyrosine kinase activity
C7I86_12210	COG0439	Biotin carboxylase
C7I86_12215	COG3224	Antibiotic biosynthesis monooxygenase
C7I86_12220	COG0590	tRNA wobble adenosine to inosine editing
C7I86_12225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7I86_12240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7I86_12255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7I86_12260	COG4251	negative regulation of phosphorylation
C7I86_12265	COG0784	Response regulator, receiver
C7I86_12270	COG0556	nucleotide-excision repair
C7I86_12295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_12300	COG2890	protein-(glutamine-N5) methyltransferase activity
C7I86_12305	COG0525	valine-tRNA ligase activity
C7I86_12310	COG5002	protein histidine kinase activity
C7I86_12320	COG0728	peptidoglycan biosynthetic process
C7I86_12335	COG0318	PFAM AMP-dependent synthetase and ligase
C7I86_12350	COG0460	homoserine dehydrogenase
C7I86_12355	COG2091	lysine biosynthetic process via aminoadipic acid
C7I86_12365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7I86_12385	COG0475	glutathione-regulated potassium exporter activity
C7I86_12400	COG4232	protein-disulfide reductase activity
C7I86_12410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7I86_12415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7I86_12420	COG0581	inorganic phosphate transmembrane transporter activity
C7I86_12435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7I86_12450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7I86_12455	COG1842	Phage shock protein A
C7I86_12470	COG0653	protein targeting
C7I86_12475	COG2119	membrane
C7I86_12485	COG2255	four-way junction helicase activity
C7I86_12490	COG2022	thiamine diphosphate biosynthetic process
C7I86_12490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_12500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7I86_12510	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C7I86_12520	COG0752	glycyl-tRNA synthetase alpha subunit
C7I86_12525	COG0668	transmembrane transport
C7I86_12530	COG5002	protein histidine kinase activity
C7I86_12545	COG2211	Major facilitator Superfamily
C7I86_12560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7I86_12565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7I86_12590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_12595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7I86_12605	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C7I86_12615	COG0745	RESPONSE REGULATOR receiver
C7I86_12620	COG0406	alpha-ribazole phosphatase activity
C7I86_12630	COG0589	response to stress
C7I86_12630	COG0475	glutathione-regulated potassium exporter activity
C7I86_12645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7I86_12655	COG1122	ATPase activity
C7I86_12665	COG0310	cobalt ion transport
C7I86_12690	COG0438	transferase activity, transferring glycosyl groups
C7I86_12695	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7I86_12710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7I86_12715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7I86_12725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7I86_12740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7I86_12755	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_12765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7I86_12775	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7I86_12780	COG0302	gtp cyclohydrolase
C7I86_12785	COG1546	Belongs to the CinA family
C7I86_12785	COG1058	Belongs to the CinA family
C7I86_12790	COG0792	nuclease activity
C7I86_12800	COG2247	cell wall binding repeat
C7I86_12800	COG2385	sporulation resulting in formation of a cellular spore
C7I86_12805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7I86_12815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7I86_12840	COG0121	glutamine amidotransferase
C7I86_12845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_12855	COG2048	Heterodisulfide reductase, subunit B
C7I86_12860	COG0762	integral membrane protein
C7I86_12875	COG4178	(ABC) transporter
C7I86_12900	COG0824	Thioesterase
C7I86_12905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7I86_12930	COG2205	protein histidine kinase activity
C7I86_12930	COG2202	Pas domain
C7I86_12945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7I86_12950	COG0646	methionine synthase
C7I86_12950	COG1410	methionine synthase
C7I86_12985	COG1410	methionine synthase
C7I86_12985	COG0646	methionine synthase
C7I86_13000	COG1309	transcriptional regulator
C7I86_13005	COG0534	Mate efflux family protein
C7I86_13020	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
C7I86_13025	COG0303	'Molybdopterin
C7I86_13030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7I86_13035	COG0746	molybdenum cofactor guanylyltransferase activity
C7I86_13035	COG0315	cyclic pyranopterin monophosphate synthase activity
C7I86_13045	COG0314	molybdopterin synthase activity
C7I86_13055	COG0606	chelatase, subunit chli
C7I86_13060	COG1032	radical SAM domain protein
C7I86_13100	COG0156	8-amino-7-oxononanoate synthase activity
C7I86_13105	COG0024	Methionine aminopeptidase
C7I86_13115	COG0494	nUDIX hydrolase
C7I86_13120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7I86_13125	COG0039	L-malate dehydrogenase activity
C7I86_13140	COG0193	aminoacyl-tRNA hydrolase activity
C7I86_13160	COG3263	regulation of cellular component size
C7I86_13170	COG0024	Methionine aminopeptidase
C7I86_13175	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
C7I86_13190	COG4243	Vitamin k epoxide reductase
C7I86_13195	COG0426	domain, Protein
C7I86_13195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_13200	COG0613	PHP domain protein
C7I86_13205	COG2251	uridine kinase activity
C7I86_13210	COG3063	Type IV pilus biogenesis stability protein PilW
C7I86_13215	COG0023	Translation Initiation Factor
C7I86_13265	COG2124	cytochrome p450
C7I86_13275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7I86_13290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7I86_13305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7I86_13315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_13325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7I86_13330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7I86_13335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7I86_13345	COG2203	Gaf domain
C7I86_13345	COG5001	Diguanylate cyclase
C7I86_13345	COG3706	GGDEF domain
C7I86_13345	COG4251	negative regulation of phosphorylation
C7I86_13350	COG0659	secondary active sulfate transmembrane transporter activity
C7I86_13355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7I86_13370	COG0305	Participates in initiation and elongation during chromosome replication
C7I86_13370	COG1372	Participates in initiation and elongation during chromosome replication
C7I86_13375	COG0714	Associated with various cellular activities
C7I86_13390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7I86_13395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7I86_13400	COG2226	methyltransferase
C7I86_13405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7I86_13410	COG0154	amidase activity
C7I86_13430	COG5001	Diguanylate cyclase
C7I86_13430	COG4251	negative regulation of phosphorylation
C7I86_13430	COG3706	GGDEF domain
C7I86_13430	COG2203	Gaf domain
C7I86_13445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7I86_13460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7I86_13470	COG1959	2 iron, 2 sulfur cluster binding
C7I86_13475	COG4251	negative regulation of phosphorylation
C7I86_13475	COG2203	Gaf domain
C7I86_13475	COG5001	Diguanylate cyclase
C7I86_13475	COG3706	GGDEF domain
C7I86_13480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7I86_13490	COG0357	Ribosomal RNA small subunit methyltransferase G
C7I86_13505	COG0719	Fe-S assembly protein
C7I86_13510	COG0396	ATPase activity
C7I86_13515	COG0719	Fe-S assembly protein
C7I86_13520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7I86_13525	COG0003	Pfam Anion-transporting ATPase
C7I86_13540	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7I86_13545	COG0720	synthase
C7I86_13560	COG0328	RNA-DNA hybrid ribonuclease activity
C7I86_13565	COG0745	RESPONSE REGULATOR receiver
C7I86_13570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7I86_13575	COG0513	Belongs to the DEAD box helicase family
C7I86_13580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7I86_13585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7I86_13590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7I86_13595	COG0443	Heat shock 70 kDa protein
C7I86_13605	COG2226	methyltransferase
C7I86_13610	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C7I86_13615	COG1012	belongs to the aldehyde dehydrogenase family
C7I86_13620	COG1216	Glycosyl transferase, family 2
C7I86_13625	COG0484	heat shock protein binding
C7I86_13635	COG0659	secondary active sulfate transmembrane transporter activity
C7I86_13645	COG1131	(ABC) transporter
C7I86_13650	COG0131	Imidazoleglycerol-phosphate dehydratase
C7I86_13660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_13665	COG4251	negative regulation of phosphorylation
C7I86_13670	COG2197	response regulator
C7I86_13685	COG0515	serine threonine protein kinase
C7I86_13695	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_13710	COG0436	Aminotransferase
C7I86_13715	COG0586	Pfam SNARE associated Golgi protein
C7I86_13720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7I86_13720	COG3264	Mechanosensitive ion channel
C7I86_13740	COG0848	biopolymer transport protein
C7I86_13745	COG0848	biopolymer transport protein
C7I86_13750	COG0811	peptide transport
C7I86_13755	COG1840	ABC-type Fe3 transport system, periplasmic component
C7I86_13765	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_13770	COG2205	protein histidine kinase activity
C7I86_13780	COG0456	acetyltransferase
C7I86_13790	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7I86_13795	COG0047	phosphoribosylformylglycinamidine synthase activity
C7I86_13820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7I86_13825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7I86_13830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7I86_13835	COG0628	permease
C7I86_13850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_13855	COG0837	glucose binding
C7I86_13860	COG1132	(ABC) transporter
C7I86_13880	COG0668	transmembrane transport
C7I86_13885	COG1492	cobalamin metabolic process
C7I86_13905	COG0469	pyruvate kinase activity
C7I86_13910	COG2081	HI0933 family
C7I86_13915	COG3118	belongs to the thioredoxin family
C7I86_13930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7I86_13945	COG0457	Tetratricopeptide repeat
C7I86_13945	COG0463	Glycosyl transferase, family 2
C7I86_13960	COG0004	ammonium transporteR
C7I86_13965	COG0800	Aldolase
C7I86_13975	COG1480	7TM receptor with intracellular HD hydrolase
C7I86_13980	COG2304	oxidoreductase activity
C7I86_13990	COG1192	Involved in chromosome partitioning
C7I86_14005	COG1473	amidohydrolase
C7I86_14015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7I86_14040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_14045	COG0784	Response regulator, receiver
C7I86_14045	COG2205	protein histidine kinase activity
C7I86_14050	COG1192	Involved in chromosome partitioning
C7I86_14070	COG0745	RESPONSE REGULATOR receiver
C7I86_14085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7I86_14095	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C7I86_14105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7I86_14120	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C7I86_14125	COG2894	cell division
C7I86_14130	COG0850	regulation of cytokinetic process
C7I86_14135	COG1716	ATPase activity
C7I86_14150	COG0574	Belongs to the PEP-utilizing enzyme family
C7I86_14150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7I86_14155	COG3706	GGDEF domain
C7I86_14155	COG0745	RESPONSE REGULATOR receiver
C7I86_14170	COG0398	Pfam SNARE associated Golgi protein
C7I86_14175	COG0737	Belongs to the 5'-nucleotidase family
C7I86_14180	COG0454	-acetyltransferase
C7I86_14195	COG1032	radical SAM domain protein
C7I86_14220	COG4585	Histidine kinase
C7I86_14225	COG2197	response regulator
C7I86_14230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7I86_14230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7I86_14235	COG2267	carboxylic ester hydrolase activity
C7I86_14240	COG4221	oxidoreductase activity
C7I86_14275	COG0024	Methionine aminopeptidase
C7I86_14295	COG1056	cytidyltransferase-related domain
C7I86_14295	COG1051	belongs to the nudix hydrolase family
C7I86_14310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7I86_14315	COG5002	protein histidine kinase activity
C7I86_14340	COG2814	Major facilitator Superfamily
C7I86_14350	COG2217	Heavy metal translocating P-type atpase
C7I86_14355	COG1742	UPF0060 membrane protein
C7I86_14360	COG0640	Transcriptional regulator
C7I86_14365	COG2217	Heavy metal translocating P-type atpase
C7I86_14370	COG5002	protein histidine kinase activity
C7I86_14375	COG0745	RESPONSE REGULATOR receiver
C7I86_14400	COG2144	transferase activity, transferring acyl groups
C7I86_14425	COG2072	flavoprotein involved in K transport
C7I86_14430	COG2197	response regulator
C7I86_14445	COG5001	Diguanylate cyclase
C7I86_14445	COG2203	Gaf domain
C7I86_14445	COG4251	negative regulation of phosphorylation
C7I86_14445	COG3706	GGDEF domain
C7I86_14450	COG1131	(ABC) transporter
C7I86_14450	COG1716	ATPase activity
C7I86_14450	COG0842	Transport permease protein
C7I86_14460	COG0515	serine threonine protein kinase
C7I86_14460	COG4991	sh3 domain protein
C7I86_14460	COG3064	Membrane
C7I86_14470	COG0401	homolog of Blt101
C7I86_14495	COG0789	Transcriptional regulator
C7I86_14545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_14550	COG0598	Magnesium transport protein CorA
C7I86_14565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7I86_14565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7I86_14590	COG0251	oxidation-reduction process
C7I86_14595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7I86_14600	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7I86_14605	COG0392	lysyltransferase activity
C7I86_14625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7I86_14650	COG2886	Uncharacterised protein family (UPF0175)
C7I86_14655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7I86_14660	COG0668	transmembrane transport
C7I86_14665	COG0205	6-phosphofructokinase activity
C7I86_14685	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7I86_14685	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7I86_14685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7I86_14685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7I86_14695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_14700	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7I86_14725	COG0438	transferase activity, transferring glycosyl groups
C7I86_14745	COG0840	transmembrane signaling receptor activity
C7I86_14750	COG0840	transmembrane signaling receptor activity
C7I86_14750	COG2203	Gaf domain
C7I86_14765	COG0784	Response regulator, receiver
C7I86_14775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7I86_14780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7I86_14785	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7I86_14790	COG1597	lipid kinase activity
C7I86_14790	COG1803	Methylglyoxal synthase
C7I86_14820	COG0857	belongs to the CobB CobQ family
C7I86_14825	COG0583	DNA-binding transcription factor activity
C7I86_14830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_14835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7I86_14840	COG3659	wide pore channel activity
C7I86_14845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_14845	COG1116	anion transmembrane transporter activity
C7I86_14850	COG1116	anion transmembrane transporter activity
C7I86_14860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7I86_14870	COG0724	RNA recognition motif
C7I86_14875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_14880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7I86_14885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7I86_14890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7I86_14895	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C7I86_14900	COG1653	transport
C7I86_14905	COG1175	transmembrane transport
C7I86_14910	COG0395	ABC-type sugar transport system, permease component
C7I86_14920	COG2205	protein histidine kinase activity
C7I86_14925	COG0741	lytic transglycosylase activity
C7I86_14935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7I86_14950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7I86_14955	COG0598	Magnesium transport protein CorA
C7I86_14960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7I86_14965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7I86_14970	COG0019	diaminopimelate decarboxylase activity
C7I86_14975	COG1160	GTP binding
C7I86_14980	COG0018	arginyl-trna synthetase
C7I86_14985	COG0463	Glycosyl transferase, family 2
C7I86_14995	COG0740	serine-type endopeptidase activity
C7I86_15000	COG0133	tryptophan synthase activity
C7I86_15010	COG1136	(ABC) transporter
C7I86_15015	COG2314	TM2 domain
C7I86_15035	COG0017	Asparaginyl-tRNA synthetase
C7I86_15055	COG0569	domain protein
C7I86_15060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7I86_15065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7I86_15070	COG0629	single-stranded DNA binding
C7I86_15080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7I86_15090	COG1192	Involved in chromosome partitioning
C7I86_15100	COG2119	membrane
C7I86_15105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7I86_15110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7I86_15120	COG1162	GTPase activity
C7I86_15130	COG0484	heat shock protein binding
C7I86_15135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C7I86_15140	COG1218	3'(2'),5'-bisphosphate nucleotidase
C7I86_15150	COG0134	indole-3-glycerol-phosphate synthase activity
C7I86_15155	COG0004	ammonium transporteR
C7I86_15160	COG0569	domain protein
C7I86_15165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7I86_15170	COG0740	serine-type endopeptidase activity
C7I86_15175	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7I86_15180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7I86_15185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7I86_15190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7I86_15200	COG0237	dephospho-CoA kinase activity
C7I86_15215	COG0517	IMP dehydrogenase activity
C7I86_15215	COG1994	Peptidase M50
C7I86_15220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7I86_15240	COG0525	valine-tRNA ligase activity
C7I86_15245	COG0713	ATP synthesis coupled electron transport
C7I86_15250	COG0839	Belongs to the complex I subunit 6 family
C7I86_15255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_15260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C7I86_15265	COG0167	dihydroorotate dehydrogenase activity
C7I86_15270	COG2166	iron-sulfur cluster assembly
C7I86_15275	COG1070	Carbohydrate kinase
C7I86_15300	COG0308	aminopeptidase N
C7I86_15305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7I86_15310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7I86_15315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7I86_15325	COG2193	ferroxidase activity
C7I86_15335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7I86_15345	COG1834	amidinotransferase
C7I86_15350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_15380	COG0745	RESPONSE REGULATOR receiver
C7I86_15385	COG0483	inositol monophosphate 1-phosphatase activity
C7I86_15400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7I86_15405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7I86_15410	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7I86_15415	COG4208	sulfate ABC transporter
C7I86_15420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_15425	COG2165	general secretion pathway protein
C7I86_15440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7I86_15455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_15460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7I86_15465	COG0731	radical SAM domain protein
C7I86_15475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7I86_15480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7I86_15490	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7I86_15495	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7I86_15510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_15565	COG0339	signal peptide processing
C7I86_15570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7I86_15595	COG1166	arginine decarboxylase activity
C7I86_15605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7I86_15625	COG1049	propionate catabolic process, 2-methylcitrate cycle
C7I86_15650	COG0069	glutamate synthase activity
C7I86_15650	COG0070	glutamate synthase
C7I86_15650	COG0067	glutamate synthase
C7I86_15655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7I86_15660	COG0505	Belongs to the CarA family
C7I86_15670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7I86_15675	COG0579	oxidoreductase
C7I86_15685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7I86_15690	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7I86_15695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7I86_15710	COG1191	sigma factor activity
C7I86_15715	COG0316	Belongs to the HesB IscA family
C7I86_15720	COG0463	Glycosyl transferase, family 2
C7I86_15725	COG2319	Wd-40 repeat
C7I86_15740	COG1691	(AIR) carboxylase
C7I86_15745	COG0739	heme binding
C7I86_15770	COG2052	Domain of unknown function (DUF370)
C7I86_15775	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7I86_15775	COG3264	Mechanosensitive ion channel
C7I86_15815	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C7I86_15830	COG0363	glucosamine-6-phosphate deaminase activity
C7I86_15850	COG2205	protein histidine kinase activity
C7I86_15855	COG3385	transposase activity
C7I86_15860	COG5001	Diguanylate cyclase
C7I86_15860	COG2203	Gaf domain
C7I86_15860	COG3706	GGDEF domain
C7I86_15860	COG4251	negative regulation of phosphorylation
C7I86_15870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_15890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7I86_15895	COG5001	Diguanylate cyclase
C7I86_15895	COG3300	MHYT domain
C7I86_15905	COG3842	ATPase activity
C7I86_15915	COG1543	Belongs to the glycosyl hydrolase 57 family
C7I86_15925	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
C7I86_15935	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
C7I86_15945	COG0457	Tetratricopeptide repeat
C7I86_15950	COG0148	phosphopyruvate hydratase activity
C7I86_15960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7I86_15975	COG0825	malonyl-CoA metabolic process
C7I86_16000	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_16025	COG4251	negative regulation of phosphorylation
C7I86_16030	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7I86_16055	COG2994	toxin metabolic process
C7I86_16070	COG0170	dolichyl monophosphate biosynthetic process
C7I86_16075	COG1473	amidohydrolase
C7I86_16080	COG3659	wide pore channel activity
C7I86_16100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7I86_16105	COG2203	Gaf domain
C7I86_16105	COG3706	GGDEF domain
C7I86_16105	COG4251	negative regulation of phosphorylation
C7I86_16105	COG5001	Diguanylate cyclase
C7I86_16130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7I86_16160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7I86_16175	COG2197	response regulator
C7I86_16220	COG2153	protein acetylation
C7I86_16270	COG4581	dead DEAH box helicase
C7I86_16280	COG0322	excinuclease ABC activity
C7I86_16285	COG0129	dihydroxy-acid dehydratase activity
C7I86_16290	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7I86_16320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7I86_16325	COG0546	phosphoglycolate phosphatase activity
C7I86_16350	COG0326	Molecular chaperone. Has ATPase activity
C7I86_16355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_16370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C7I86_16375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7I86_16385	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7I86_16420	COG0723	plastoquinol--plastocyanin reductase activity
C7I86_16435	COG1842	Phage shock protein A
C7I86_16455	COG1064	alcohol dehydrogenase
C7I86_16460	COG0137	argininosuccinate synthase activity
C7I86_16475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7I86_16500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_16515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7I86_16520	COG0549	Belongs to the carbamate kinase family
C7I86_16540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_16545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7I86_16550	COG0577	efflux transmembrane transporter activity
C7I86_16550	COG1136	(ABC) transporter
C7I86_16555	COG0735	belongs to the Fur family
C7I86_16565	COG0138	bifunctional purine biosynthesis protein purh
C7I86_16585	COG0515	serine threonine protein kinase
C7I86_16610	COG0587	DNA-directed DNA polymerase activity
C7I86_16615	COG0481	GTPase activity
C7I86_16620	COG0435	Glutathione S-transferase
C7I86_16640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7I86_16640	COG0140	phosphoribosyl-ATP diphosphatase activity
C7I86_16645	COG0523	cobalamin synthesis protein
C7I86_16730	COG3385	transposase activity
C7I86_16830	COG4453	Protein conserved in bacteria
C7I86_16870	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7I86_16930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7I86_16985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7I86_17040	COG1518	maintenance of DNA repeat elements
C7I86_17135	COG1468	defense response to virus
C7I86_17135	COG1518	maintenance of DNA repeat elements
C7I86_17190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7I86_17330	COG1846	Transcriptional regulator
C7I86_17375	COG2070	2-Nitropropane dioxygenase
C7I86_17395	COG2319	Wd-40 repeat
C7I86_17395	COG3903	Transcriptional regulator
C7I86_17550	COG2361	Protein of unknown function DUF86
C7I86_17565	COG3093	addiction module antidote protein HigA
C7I86_17570	COG1104	cysteine desulfurase activity
C7I86_17635	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7I86_17695	COG0438	transferase activity, transferring glycosyl groups
C7I86_17705	COG0438	transferase activity, transferring glycosyl groups
C7I86_17740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7I86_17750	COG3706	GGDEF domain
C7I86_17750	COG0745	RESPONSE REGULATOR receiver
C7I86_17755	COG2205	protein histidine kinase activity
C7I86_17755	COG0784	Response regulator, receiver
C7I86_17755	COG5002	protein histidine kinase activity
C7I86_17835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7I86_17850	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_17860	COG3878	Protein conserved in bacteria
C7I86_17890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7I86_17990	COG1192	Involved in chromosome partitioning
C7I86_18080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7I86_18085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7I86_18120	COG5001	Diguanylate cyclase
C7I86_18125	COG4191	Histidine kinase
C7I86_18125	COG0784	Response regulator, receiver
C7I86_18285	COG1192	Involved in chromosome partitioning
C7I86_18305	COG0745	RESPONSE REGULATOR receiver
C7I86_18395	COG2340	Cysteine-rich secretory protein family
C7I86_18590	COG3177	Filamentation induced by cAMP protein fic
C7I86_18600	COG4680	protein conserved in bacteria
C7I86_18610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7I86_18615	COG1451	nucleotide metabolic process
C7I86_18625	COG3385	transposase activity
C7I86_18635	COG2340	Cysteine-rich secretory protein family