locus-tag	class	description
MYO_110	COG0142	geranyltranstransferase activity
MYO_1100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MYO_11000	COG1104	cysteine desulfurase activity
MYO_110000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MYO_110010	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MYO_110040	COG0501	Belongs to the peptidase M48B family
MYO_110050	COG0539	negative regulation of cytoplasmic translation
MYO_110070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MYO_110080	COG1132	(ABC) transporter
MYO_110090	COG0469	pyruvate kinase activity
MYO_110130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MYO_110140	COG1268	BioY protein
MYO_110150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MYO_110180	COG3659	wide pore channel activity
MYO_110210	COG0058	SHG alpha-glucan phosphorylase activity
MYO_110230	COG0575	Belongs to the CDS family
MYO_110280	COG1970	mechanosensitive ion channel activity
MYO_110290	COG0632	four-way junction helicase activity
MYO_110300	COG1836	PFAM Integral membrane protein DUF92
MYO_110310	COG0446	pyridine nucleotide-disulphide oxidoreductase
MYO_110320	COG0724	RNA recognition motif
MYO_110330	COG0154	amidase activity
MYO_110340	COG0739	heme binding
MYO_110350	COG0509	glycine decarboxylation via glycine cleavage system
MYO_110380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MYO_11040	COG0582	viral genome integration into host DNA
MYO_110420	COG1316	TRANSCRIPTIONal
MYO_110440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MYO_110460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MYO_110470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MYO_110490	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_110520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MYO_110550	COG0322	excinuclease ABC activity
MYO_11060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MYO_11060	COG2022	thiamine diphosphate biosynthetic process
MYO_110600	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MYO_110620	COG3258	Cytochrome c
MYO_110630	COG0723	plastoquinol--plastocyanin reductase activity
MYO_110680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MYO_110730	COG2319	Wd-40 repeat
MYO_110740	COG2319	Wd-40 repeat
MYO_110780	COG1082	Xylose isomerase domain protein TIM barrel
MYO_110810	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MYO_110860	COG1366	Belongs to the anti-sigma-factor antagonist family
MYO_110890	COG2770	Histidine kinase
MYO_110890	COG2208	phosphoserine phosphatase activity
MYO_11090	COG5002	protein histidine kinase activity
MYO_110960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MYO_110970	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MYO_111020	COG1741	Belongs to the pirin family
MYO_111040	COG1193	negative regulation of DNA recombination
MYO_111050	COG0631	protein serine/threonine phosphatase activity
MYO_111060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MYO_111070	COG3937	granule-associated protein
MYO_11110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MYO_111110	COG1181	Belongs to the D-alanine--D-alanine ligase family
MYO_111120	COG3932	Exopolysaccharide synthesis, ExoD
MYO_111130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MYO_111150	COG0360	Binds together with S18 to 16S ribosomal RNA
MYO_111160	COG0179	Fumarylacetoacetate (FAA) hydrolase
MYO_111170	COG1413	lyase activity
MYO_111180	COG0641	radical SAM
MYO_111250	COG0083	homoserine kinase activity
MYO_111270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MYO_111280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_111300	COG0196	riboflavin kinase activity
MYO_111340	COG0180	Tryptophanyl-tRNA synthetase
MYO_111360	COG1713	HD superfamily hydrolase involved in NAD metabolism
MYO_111370	COG0799	negative regulation of ribosome biogenesis
MYO_111390	COG0181	hydroxymethylbilane synthase activity
MYO_111400	COG0427	acetyl-CoA hydrolase
MYO_111410	COG0280	phosphate acetyltransferase
MYO_111410	COG0857	belongs to the CobB CobQ family
MYO_111430	COG1489	DNA binding
MYO_111450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MYO_111460	COG0602	queuosine metabolic process
MYO_111470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MYO_111480	COG0612	Peptidase, M16
MYO_111490	COG0612	Peptidase, M16
MYO_11150	COG0704	Plays a role in the regulation of phosphate uptake
MYO_111510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MYO_111540	COG1372	Participates in initiation and elongation during chromosome replication
MYO_111540	COG0187	DNA topoisomerase II activity
MYO_111570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MYO_111570	COG0646	methionine synthase
MYO_111590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MYO_11160	COG0779	Required for maturation of 30S ribosomal subunits
MYO_111640	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_111660	COG2197	response regulator
MYO_111670	COG3706	GGDEF domain
MYO_111670	COG4251	negative regulation of phosphorylation
MYO_111670	COG5001	Diguanylate cyclase
MYO_111670	COG2203	Gaf domain
MYO_111690	COG0616	signal peptide processing
MYO_11170	COG0195	Participates in both transcription termination and antitermination
MYO_111710	COG0596	Alpha beta hydrolase
MYO_111720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MYO_111740	COG0747	negative chemotaxis
MYO_111760	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
MYO_11180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MYO_111840	COG4968	Prepilin-type N-terminal cleavage methylation domain
MYO_111850	COG4968	Prepilin-type N-terminal cleavage methylation domain
MYO_111900	COG1357	PFAM Pentapeptide repeats (8 copies)
MYO_111910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MYO_111920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MYO_111940	COG2199	diguanylate cyclase activity
MYO_111950	COG0750	zinc metalloprotease
MYO_111960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MYO_111980	COG0590	tRNA wobble adenosine to inosine editing
MYO_1120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MYO_112000	COG0415	Belongs to the DNA photolyase family
MYO_112020	COG3429	Glucose-6-phosphate dehydrogenase subunit
MYO_112020	COG3409	Peptidoglycan-binding domain 1 protein
MYO_112040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MYO_112050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MYO_112070	COG1122	ATPase activity
MYO_112080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MYO_112100	COG0678	peroxiredoxin activity
MYO_112180	COG1252	NADH dehydrogenase
MYO_112200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MYO_112250	COG0415	Belongs to the DNA photolyase family
MYO_112280	COG1595	DNA-templated transcription, initiation
MYO_112360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MYO_112380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MYO_112390	COG3339	Conserved Protein
MYO_112410	COG0312	modulator of DNA gyrase
MYO_112420	COG0482	sulfurtransferase activity
MYO_112450	COG0488	(ABC) transporter
MYO_112460	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MYO_112480	COG0284	orotidine-5'-phosphate decarboxylase activity
MYO_112560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MYO_112580	COG0697	spore germination
MYO_11260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MYO_112650	COG0583	DNA-binding transcription factor activity
MYO_112710	COG2814	Major facilitator Superfamily
MYO_112720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MYO_112730	COG0573	inorganic phosphate transmembrane transporter activity
MYO_112740	COG0581	inorganic phosphate transmembrane transporter activity
MYO_112750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MYO_112760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MYO_112770	COG2154	pterin-4-alpha-carbinolamine dehydratase
MYO_11280	COG0011	TIGRFAM Protein of
MYO_112820	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MYO_112820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MYO_112830	COG1562	ergosterol biosynthetic process
MYO_112840	COG3788	relative of glutathione S-transferase, MAPEG superfamily
MYO_112850	COG0831	urea catabolic process
MYO_112870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MYO_11290	COG0589	response to stress
MYO_112910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MYO_112920	COG0730	response to heat
MYO_112940	COG2188	Transcriptional regulator
MYO_112970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MYO_112980	COG0640	Transcriptional regulator
MYO_112990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MYO_1130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MYO_113000	COG1754	DNA topoisomerase type I activity
MYO_113000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MYO_113070	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
MYO_11310	COG0123	including yeast histone deacetylase and acetoin utilization protein
MYO_113130	COG2264	protein methyltransferase activity
MYO_113140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MYO_113170	COG0386	Belongs to the glutathione peroxidase family
MYO_113180	COG0183	Belongs to the thiolase family
MYO_113190	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_11320	COG0010	Belongs to the arginase family
MYO_113210	COG3850	Histidine kinase
MYO_113210	COG3437	response regulator, receiver
MYO_113210	COG2205	protein histidine kinase activity
MYO_113210	COG4999	Histidine kinase
MYO_113250	COG4242	Belongs to the peptidase S51 family
MYO_113260	COG0189	ligase activity
MYO_113260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MYO_11330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MYO_113320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MYO_113330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MYO_113350	COG0285	dihydrofolate synthase activity
MYO_113390	COG4636	protein conserved in cyanobacteria
MYO_113410	COG1606	tRNA processing
MYO_113430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MYO_113440	COG2045	Belongs to the ComB family
MYO_113450	COG0778	Nitroreductase
MYO_113460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MYO_113480	COG0516	GMP reductase activity
MYO_113490	COG0395	ABC-type sugar transport system, permease component
MYO_113500	COG3268	Saccharopine dehydrogenase
MYO_113530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MYO_113540	COG1121	(ABC) transporter
MYO_113550	COG0803	Belongs to the bacterial solute-binding protein 9 family
MYO_113570	COG4251	negative regulation of phosphorylation
MYO_113580	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MYO_113600	COG0583	DNA-binding transcription factor activity
MYO_113610	COG0025	NhaP-type Na H and K H
MYO_113620	COG2197	response regulator
MYO_113630	COG5002	protein histidine kinase activity
MYO_113640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MYO_113650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MYO_113670	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MYO_113680	COG2205	protein histidine kinase activity
MYO_113700	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MYO_113740	COG2385	sporulation resulting in formation of a cellular spore
MYO_113750	COG0649	NAD binding
MYO_113780	COG0429	hydrolase of the alpha beta-hydrolase fold
MYO_113800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MYO_113810	COG3536	Protein conserved in bacteria
MYO_113820	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MYO_113830	COG0716	FMN binding
MYO_113850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MYO_113860	COG0012	GTP binding
MYO_113870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MYO_113980	COG3842	ATPase activity
MYO_1140	COG1120	ATPase activity
MYO_114000	COG1840	ABC-type Fe3 transport system, periplasmic component
MYO_114010	COG0222	ribosome binding
MYO_114030	COG2066	Belongs to the glutaminase family
MYO_114070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MYO_11410	COG2099	Precorrin-6x reductase
MYO_114100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MYO_114110	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MYO_114120	COG1333	cytochrome c biogenesis protein
MYO_114140	COG1657	PFAM Prenyltransferase squalene oxidase
MYO_114230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MYO_114250	COG1494	fructose-1,6-bisphosphatase
MYO_114280	COG2346	COG2346, Truncated hemoglobins
MYO_114290	COG4999	Histidine kinase
MYO_114290	COG3850	Histidine kinase
MYO_114290	COG3437	response regulator, receiver
MYO_114290	COG2205	protein histidine kinase activity
MYO_114310	COG3437	response regulator, receiver
MYO_114320	COG1917	Cupin 2, conserved barrel domain protein
MYO_114330	COG0552	protein localization to endoplasmic reticulum
MYO_114350	COG5002	protein histidine kinase activity
MYO_114350	COG2205	protein histidine kinase activity
MYO_114350	COG0784	Response regulator, receiver
MYO_114360	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MYO_114380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MYO_11440	COG1007	ATP synthesis coupled electron transport
MYO_114420	COG0667	Aldo Keto reductase
MYO_114430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MYO_114450	COG0442	prolyl-tRNA aminoacylation
MYO_114470	COG4372	Transposase
MYO_114480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MYO_114520	COG0438	transferase activity, transferring glycosyl groups
MYO_114530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MYO_114540	COG0416	fatty acid biosynthetic process
MYO_114550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MYO_114580	COG0347	Belongs to the P(II) protein family
MYO_114590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MYO_114640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MYO_114650	COG0473	3-isopropylmalate dehydrogenase activity
MYO_114670	COG1575	Belongs to the MenA family. Type 1 subfamily
MYO_114690	COG0656	L-ascorbic acid biosynthetic process
MYO_114760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MYO_114790	COG2161	toxin-antitoxin pair type II binding
MYO_114820	COG3385	transposase activity
MYO_114840	COG3385	transposase activity
MYO_114860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MYO_114860	COG0517	IMP dehydrogenase activity
MYO_114890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MYO_11490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MYO_114910	COG1215	transferase activity, transferring glycosyl groups
MYO_114950	COG1216	Glycosyl transferase, family 2
MYO_114960	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MYO_114990	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_1150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MYO_11500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MYO_115040	COG0463	Glycosyl transferase, family 2
MYO_115050	COG0113	porphobilinogen synthase activity
MYO_115060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MYO_115070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MYO_11510	COG0426	domain, Protein
MYO_11510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MYO_115110	COG0312	modulator of DNA gyrase
MYO_115120	COG2890	protein-(glutamine-N5) methyltransferase activity
MYO_115130	COG2205	protein histidine kinase activity
MYO_115160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MYO_115170	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MYO_115220	COG0438	transferase activity, transferring glycosyl groups
MYO_115240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MYO_115240	COG2205	protein histidine kinase activity
MYO_115250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MYO_115260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MYO_115270	COG0612	Peptidase, M16
MYO_115280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MYO_115290	COG3259	Nickel-dependent hydrogenase
MYO_11530	COG0426	domain, Protein
MYO_11530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MYO_115320	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
MYO_115330	COG1034	ATP synthesis coupled electron transport
MYO_11540	COG0793	Belongs to the peptidase S41A family
MYO_115400	COG0702	epimerase
MYO_115470	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MYO_115480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MYO_11550	COG0009	L-threonylcarbamoyladenylate synthase
MYO_115510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MYO_115530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MYO_115540	COG0673	inositol 2-dehydrogenase activity
MYO_115570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MYO_115580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MYO_11560	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MYO_115660	COG0095	Lipoate-protein ligase
MYO_11570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MYO_115700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MYO_115720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MYO_115750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MYO_115760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MYO_115770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MYO_115780	COG0457	Tetratricopeptide repeat
MYO_115790	COG1160	GTP binding
MYO_11580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MYO_115830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MYO_115850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MYO_115860	COG0052	Belongs to the universal ribosomal protein uS2 family
MYO_115880	COG0387	Pfam Sodium calcium exchanger
MYO_115890	COG0717	Belongs to the dCTP deaminase family
MYO_11590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MYO_115950	COG3385	transposase activity
MYO_115960	COG1253	flavin adenine dinucleotide binding
MYO_115980	COG3046	protein related to deoxyribodipyrimidine photolyase
MYO_115990	COG0517	IMP dehydrogenase activity
MYO_115990	COG0516	GMP reductase activity
MYO_11600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MYO_116010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MYO_116050	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MYO_116050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MYO_116060	COG0288	reversible hydration of carbon dioxide
MYO_116070	COG1045	serine acetyltransferase
MYO_116080	COG0166	Belongs to the GPI family
MYO_116090	COG3239	Fatty acid desaturase
MYO_116100	COG1672	PFAM Archaeal ATPase
MYO_116110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MYO_116120	COG2010	Cytochrome c
MYO_116130	COG0359	binds to the 23S rRNA
MYO_116150	COG1032	radical SAM domain protein
MYO_11620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MYO_116200	COG0298	carbon dioxide binding
MYO_116210	COG0109	protoheme IX farnesyltransferase activity
MYO_116220	COG1612	heme a metabolic process
MYO_116260	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MYO_116270	COG1716	ATPase activity
MYO_116270	COG5001	Diguanylate cyclase
MYO_116280	COG3631	Ketosteroid isomerase-related protein
MYO_11630	COG0356	it plays a direct role in the translocation of protons across the membrane
MYO_116300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MYO_116300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MYO_116320	COG0107	imidazoleglycerol-phosphate synthase activity
MYO_116370	COG2205	protein histidine kinase activity
MYO_116370	COG2202	Pas domain
MYO_116400	COG4783	chaperone-mediated protein folding
MYO_116410	COG3850	Histidine kinase
MYO_116410	COG2205	protein histidine kinase activity
MYO_116410	COG4999	Histidine kinase
MYO_116410	COG3437	response regulator, receiver
MYO_116430	COG4956	integral membrane protein (PIN domain superfamily)
MYO_116460	COG1160	GTP binding
MYO_116480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MYO_11650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MYO_116510	COG0432	Pfam Uncharacterised protein family UPF0047
MYO_116520	COG2197	response regulator
MYO_116530	COG3842	ATPase activity
MYO_116550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MYO_116560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MYO_116580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MYO_116590	COG5398	heme oxygenase
MYO_116600	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MYO_116620	COG1316	TRANSCRIPTIONal
MYO_116640	COG3706	GGDEF domain
MYO_116640	COG0745	RESPONSE REGULATOR receiver
MYO_116650	COG2770	Histidine kinase
MYO_116650	COG2208	phosphoserine phosphatase activity
MYO_116660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MYO_116680	COG0539	negative regulation of cytoplasmic translation
MYO_116690	COG0358	DNA primase activity
MYO_116710	COG0009	L-threonylcarbamoyladenylate synthase
MYO_116750	COG0589	response to stress
MYO_11680	COG0714	Associated with various cellular activities
MYO_116800	COG2082	Precorrin-8x methylmutase
MYO_116820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MYO_116830	COG0594	ribonuclease P activity
MYO_116850	COG0706	membrane insertase activity
MYO_116870	COG0484	heat shock protein binding
MYO_116880	COG0483	inositol monophosphate 1-phosphatase activity
MYO_116890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MYO_11690	COG0316	Belongs to the HesB IscA family
MYO_116910	COG0791	NLP P60 protein
MYO_116940	COG0540	Belongs to the ATCase OTCase family
MYO_116970	COG1215	transferase activity, transferring glycosyl groups
MYO_116990	COG0300	oxidoreductase activity
MYO_116990	COG3000	fatty acid hydroxylase
MYO_1170	COG4977	sequence-specific DNA binding
MYO_11700	COG0697	spore germination
MYO_117000	COG2211	Major facilitator Superfamily
MYO_117030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MYO_117060	COG0723	plastoquinol--plastocyanin reductase activity
MYO_117070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MYO_117080	COG2274	protein secretion by the type I secretion system
MYO_117090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MYO_117100	COG2192	nodulation
MYO_117120	COG0772	Belongs to the SEDS family
MYO_117130	COG0405	Gamma-glutamyltransferase
MYO_117160	COG3659	wide pore channel activity
MYO_11720	COG1127	ABC transporter
MYO_117240	COG0037	tRNA processing
MYO_117250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MYO_117260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_117270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_117280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_117360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MYO_117380	COG0628	permease
MYO_11740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MYO_117410	COG0066	3-isopropylmalate dehydratase activity
MYO_117420	COG0504	CTP synthase activity
MYO_117440	COG2204	response regulator
MYO_117460	COG0259	pyridoxamine-phosphate oxidase activity
MYO_117490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MYO_117520	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MYO_117530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MYO_117540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MYO_117540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MYO_117550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MYO_117570	COG1619	proteins homologs of microcin C7 resistance protein MccF
MYO_117580	COG1357	PFAM Pentapeptide repeats (8 copies)
MYO_117610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MYO_117630	COG0051	transcription antitermination factor activity, RNA binding
MYO_117640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MYO_117650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MYO_117660	COG0049	tRNA binding
MYO_117670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MYO_117690	COG0151	Belongs to the GarS family
MYO_117710	COG0698	ribose 5-phosphate isomerase
MYO_117770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MYO_117780	COG2046	Belongs to the sulfate adenylyltransferase family
MYO_117790	COG0297	glycogen (starch) synthase activity
MYO_117820	COG0644	oxidoreductase
MYO_117830	COG0371	Dehydrogenase
MYO_117860	COG2119	membrane
MYO_117870	COG0386	Belongs to the glutathione peroxidase family
MYO_117890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MYO_11790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MYO_117940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MYO_117950	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MYO_117970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MYO_117980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MYO_118000	COG0375	protein maturation
MYO_118030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MYO_118040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MYO_118050	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MYO_118060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MYO_118070	COG1134	teichoic acid transport
MYO_118120	COG1012	belongs to the aldehyde dehydrogenase family
MYO_118150	COG3385	transposase activity
MYO_11820	COG0163	prenyltransferase activity
MYO_118220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MYO_118240	COG1304	FMN binding
MYO_118250	COG0745	RESPONSE REGULATOR receiver
MYO_118270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MYO_118290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MYO_118290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MYO_118300	COG5001	Diguanylate cyclase
MYO_118300	COG3706	GGDEF domain
MYO_118300	COG4251	negative regulation of phosphorylation
MYO_118300	COG2203	Gaf domain
MYO_118310	COG0784	Response regulator, receiver
MYO_118330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MYO_118330	COG0072	phenylalanine-tRNA ligase activity
MYO_118340	COG0515	serine threonine protein kinase
MYO_118340	COG1357	PFAM Pentapeptide repeats (8 copies)
MYO_118350	COG2197	response regulator
MYO_118360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MYO_118380	COG0157	Belongs to the NadC ModD family
MYO_11840	COG0589	response to stress
MYO_118410	COG2082	Precorrin-8x methylmutase
MYO_118420	COG0612	Peptidase, M16
MYO_118430	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MYO_118450	COG0656	L-ascorbic acid biosynthetic process
MYO_118460	COG3588	fructose-bisphosphate aldolase
MYO_118480	COG0798	PFAM Bile acid sodium symporter
MYO_118490	COG0431	NADPH-dependent FMN reductase
MYO_118500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MYO_118540	COG0488	(ABC) transporter
MYO_118560	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MYO_11860	COG5001	Diguanylate cyclase
MYO_11860	COG1716	ATPase activity
MYO_118600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MYO_118610	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MYO_118620	COG0561	phosphatase activity
MYO_118640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MYO_118650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MYO_118670	COG0215	cysteine-tRNA ligase activity
MYO_118680	COG0424	maF-like protein
MYO_118710	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MYO_118720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MYO_118730	COG0463	Glycosyl transferase, family 2
MYO_118740	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MYO_118770	COG1472	Belongs to the glycosyl hydrolase 3 family
MYO_118780	COG2816	NAD+ diphosphatase activity
MYO_118790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MYO_118800	COG1280	lysine exporter protein (LysE YggA)
MYO_118830	COG0564	pseudouridine synthase activity
MYO_118850	COG0438	transferase activity, transferring glycosyl groups
MYO_118930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MYO_118960	COG0438	transferase activity, transferring glycosyl groups
MYO_118980	COG0500	methyltransferase
MYO_118990	COG0542	response to heat
MYO_11900	COG1234	tRNA 3'-trailer cleavage
MYO_119010	COG0572	uridine kinase
MYO_119020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MYO_119030	COG0561	phosphatase activity
MYO_119060	COG0571	ribonuclease III activity
MYO_119070	COG0390	transport system, permease component
MYO_119080	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MYO_119090	COG2161	toxin-antitoxin pair type II binding
MYO_119110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MYO_119120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MYO_119120	COG0426	domain, Protein
MYO_119130	COG0497	DNA recombination
MYO_119150	COG3751	2OG-Fe(II) oxygenase superfamily
MYO_119180	COG2161	toxin-antitoxin pair type II binding
MYO_11920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MYO_119230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MYO_119240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MYO_119270	COG1446	asparaginase
MYO_119280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MYO_119300	COG0832	Belongs to the urease beta subunit family
MYO_119320	COG2226	methyltransferase
MYO_119350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MYO_119370	COG0025	NhaP-type Na H and K H
MYO_119390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MYO_119410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MYO_119490	COG3239	Fatty acid desaturase
MYO_11950	COG0631	protein serine/threonine phosphatase activity
MYO_119510	COG1950	PFAM Membrane protein of
MYO_119540	COG1253	flavin adenine dinucleotide binding
MYO_119550	COG0228	four-way junction DNA binding
MYO_119590	COG2010	Cytochrome c
MYO_119620	COG0802	atpase or kinase
MYO_119630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MYO_119630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MYO_119680	COG0126	phosphoglycerate kinase activity
MYO_119690	COG0583	DNA-binding transcription factor activity
MYO_11970	COG4451	ribulose bisphosphate carboxylase, small
MYO_11970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MYO_119700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MYO_119770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MYO_11980	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
MYO_119800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MYO_119810	COG0347	Belongs to the P(II) protein family
MYO_119840	COG0135	phosphoribosylanthranilate isomerase activity
MYO_119850	COG0697	spore germination
MYO_119870	COG0418	dihydroorotase activity
MYO_119880	COG2226	methyltransferase
MYO_11990	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MYO_119910	COG1672	PFAM Archaeal ATPase
MYO_119910	COG2319	Wd-40 repeat
MYO_120	COG1187	pseudouridine synthase activity
MYO_12000	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MYO_120000	COG0515	serine threonine protein kinase
MYO_120000	COG2815	serine threonine protein kinase
MYO_120050	COG0233	cytoplasmic translational termination
MYO_120060	COG0528	UMP kinase activity
MYO_120070	COG1598	PFAM Uncharacterised protein family UPF0150
MYO_120080	COG0542	response to heat
MYO_12010	COG0493	'glutamate synthase
MYO_120140	COG0740	serine-type endopeptidase activity
MYO_120150	COG0740	serine-type endopeptidase activity
MYO_120160	COG0006	proline dipeptidase activity
MYO_120170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MYO_120210	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
MYO_120230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MYO_120240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MYO_120300	COG2165	general secretion pathway protein
MYO_120320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MYO_120390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MYO_120430	COG0105	UTP biosynthetic process
MYO_120490	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MYO_120500	COG2937	Belongs to the GPAT DAPAT family
MYO_120510	COG0501	Belongs to the peptidase M48B family
MYO_120550	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MYO_120570	COG0463	Glycosyl transferase, family 2
MYO_120590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MYO_120620	COG0508	dehydrogenase complex catalyzes the overall conversion of
MYO_120640	COG2217	Heavy metal translocating P-type atpase
MYO_120660	COG0217	transcriptional regulatory protein
MYO_120670	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MYO_120680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MYO_120690	COG0739	heme binding
MYO_120700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MYO_120710	COG0321	lipoyl(octanoyl) transferase activity
MYO_120740	COG0297	glycogen (starch) synthase activity
MYO_120770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MYO_120780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MYO_120790	COG2198	Histidine kinase
MYO_120790	COG0643	Histidine kinase
MYO_120860	COG1178	ABC-type Fe3 transport system permease component
MYO_120870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MYO_120920	COG2197	response regulator
MYO_120940	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_120990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MYO_120990	COG0237	dephospho-CoA kinase activity
MYO_121070	COG0517	IMP dehydrogenase activity
MYO_121070	COG0516	GMP reductase activity
MYO_121090	COG1937	Protein conserved in bacteria
MYO_12110	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MYO_12110	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MYO_121110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MYO_121150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MYO_121160	COG0443	Heat shock 70 kDa protein
MYO_121170	COG0484	heat shock protein binding
MYO_121200	COG1587	Uroporphyrinogen-III synthase
MYO_121210	COG2319	Wd-40 repeat
MYO_121240	COG3385	transposase activity
MYO_121270	COG1381	Involved in DNA repair and RecF pathway recombination
MYO_12130	COG1982	Orn Lys Arg decarboxylase major
MYO_121300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MYO_121340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MYO_121350	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MYO_121360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MYO_121370	COG5001	Diguanylate cyclase
MYO_121390	COG1187	pseudouridine synthase activity
MYO_12140	COG0686	Belongs to the AlaDH PNT family
MYO_121400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MYO_121460	COG1012	belongs to the aldehyde dehydrogenase family
MYO_121470	COG5002	protein histidine kinase activity
MYO_121480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MYO_121490	COG2308	Evidence 4 Homologs of previously reported genes of
MYO_12150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MYO_121550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MYO_121570	COG0346	lactoylglutathione lyase activity
MYO_121580	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_121590	COG0742	ribosomal rna small subunit methyltransferase
MYO_121600	COG0438	transferase activity, transferring glycosyl groups
MYO_121610	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MYO_121650	COG1104	cysteine desulfurase activity
MYO_121660	COG1040	competence protein
MYO_121670	COG1376	ErfK ybiS ycfS ynhG family protein
MYO_121700	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MYO_121720	COG3659	wide pore channel activity
MYO_121730	COG0477	Major facilitator Superfamily
MYO_121740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MYO_121750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MYO_121760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MYO_121770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MYO_121780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MYO_121790	COG2003	Belongs to the UPF0758 family
MYO_121860	COG1131	(ABC) transporter
MYO_121880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MYO_12190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MYO_121900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MYO_121920	COG0450	alkyl hydroperoxide reductase
MYO_121930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MYO_121950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MYO_121970	COG1231	oxidoreductase activity
MYO_121980	COG2205	protein histidine kinase activity
MYO_1220	COG2207	Transcriptional regulator
MYO_122000	COG0149	triose-phosphate isomerase activity
MYO_122010	COG0628	permease
MYO_122040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MYO_122050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MYO_122080	COG0571	ribonuclease III activity
MYO_122090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MYO_12210	COG0673	inositol 2-dehydrogenase activity
MYO_122140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MYO_122180	COG3385	transposase activity
MYO_12220	COG0700	Nucleoside recognition
MYO_122200	COG3385	transposase activity
MYO_122230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MYO_122240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MYO_12230	COG2715	membrane protein required for spore maturation
MYO_122310	COG0601	transmembrane transport
MYO_122320	COG0124	histidyl-tRNA synthetase
MYO_12240	COG1640	4-alpha-glucanotransferase
MYO_122410	COG0542	response to heat
MYO_122420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MYO_122430	COG0191	fructose-bisphosphate aldolase activity
MYO_122440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MYO_122480	COG0793	Belongs to the peptidase S41A family
MYO_122490	COG1850	ribulose-bisphosphate carboxylase activity
MYO_122510	COG4451	ribulose bisphosphate carboxylase, small
MYO_122530	COG1285	pathogenesis
MYO_122550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MYO_122560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MYO_122580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MYO_122590	COG0114	fumarate hydratase activity
MYO_12260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MYO_122650	COG0436	Aminotransferase
MYO_122660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MYO_122670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MYO_122680	COG0616	signal peptide processing
MYO_122690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MYO_122710	COG0519	Catalyzes the synthesis of GMP from XMP
MYO_122710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MYO_122730	COG1968	undecaprenyl-diphosphatase activity
MYO_122770	COG5322	oxidoreductase activity
MYO_122780	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MYO_122800	COG0751	glycine-tRNA ligase activity
MYO_122820	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MYO_122830	COG5002	protein histidine kinase activity
MYO_122840	COG0445	tRNA wobble uridine modification
MYO_122880	COG3794	PFAM blue (type 1) copper domain protein
MYO_12290	COG3706	GGDEF domain
MYO_12290	COG5001	Diguanylate cyclase
MYO_12290	COG4251	negative regulation of phosphorylation
MYO_12290	COG2203	Gaf domain
MYO_122910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MYO_122920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MYO_122930	COG0805	protein transport
MYO_122940	COG2084	Dehydrogenase
MYO_122960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MYO_122980	COG0586	Pfam SNARE associated Golgi protein
MYO_122990	COG3118	belongs to the thioredoxin family
MYO_1230	COG2226	methyltransferase
MYO_123000	COG3751	2OG-Fe(II) oxygenase superfamily
MYO_123010	COG0459	protein refolding
MYO_123020	COG1131	(ABC) transporter
MYO_123070	COG4399	Belongs to the UPF0754 family
MYO_123080	COG0824	Thioesterase
MYO_123090	COG4948	Mandelate Racemase Muconate Lactonizing
MYO_123100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MYO_123110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MYO_123120	COG0511	ligase activity, forming carbon-carbon bonds
MYO_123160	COG0277	FAD linked oxidase domain protein
MYO_123210	COG0436	Aminotransferase
MYO_123220	COG0372	Belongs to the citrate synthase family
MYO_123230	COG2062	phosphohistidine phosphatase, SixA
MYO_123240	COG0596	Alpha beta hydrolase
MYO_123270	COG1234	tRNA 3'-trailer cleavage
MYO_12330	COG0175	sulfate reduction
MYO_123300	COG0788	formyltetrahydrofolate deformylase activity
MYO_123340	COG0625	glutathione transferase activity
MYO_123360	COG0440	acetolactate synthase activity
MYO_123380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MYO_123390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MYO_12340	COG1420	regulation of RNA biosynthetic process
MYO_123410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MYO_123420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MYO_123430	COG0628	permease
MYO_123500	COG0628	permease
MYO_123510	COG0443	Heat shock 70 kDa protein
MYO_123520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MYO_123530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MYO_123540	COG0116	Belongs to the methyltransferase superfamily
MYO_123560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MYO_123560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MYO_123570	COG0612	Peptidase, M16
MYO_123580	COG0489	protein tyrosine kinase activity
MYO_123590	COG0439	Biotin carboxylase
MYO_12360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MYO_123600	COG3224	Antibiotic biosynthesis monooxygenase
MYO_123610	COG0590	tRNA wobble adenosine to inosine editing
MYO_123620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MYO_123650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MYO_123670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MYO_123680	COG4251	negative regulation of phosphorylation
MYO_123690	COG0784	Response regulator, receiver
MYO_12370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MYO_123700	COG0556	nucleotide-excision repair
MYO_123750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MYO_123760	COG2890	protein-(glutamine-N5) methyltransferase activity
MYO_123770	COG0525	valine-tRNA ligase activity
MYO_123780	COG5002	protein histidine kinase activity
MYO_123800	COG0728	peptidoglycan biosynthetic process
MYO_123830	COG0318	PFAM AMP-dependent synthetase and ligase
MYO_123860	COG0460	homoserine dehydrogenase
MYO_123870	COG2091	lysine biosynthetic process via aminoadipic acid
MYO_123890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MYO_12390	COG0003	Pfam Anion-transporting ATPase
MYO_123930	COG0475	glutathione-regulated potassium exporter activity
MYO_123960	COG4232	protein-disulfide reductase activity
MYO_123980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MYO_123990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MYO_12400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MYO_124000	COG0581	inorganic phosphate transmembrane transporter activity
MYO_124030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MYO_124060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MYO_124070	COG1842	Phage shock protein A
MYO_124090	COG0653	protein targeting
MYO_124100	COG2119	membrane
MYO_124120	COG2255	four-way junction helicase activity
MYO_124130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MYO_124130	COG2022	thiamine diphosphate biosynthetic process
MYO_124150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MYO_124170	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MYO_124190	COG0752	glycyl-tRNA synthetase alpha subunit
MYO_124200	COG0668	transmembrane transport
MYO_124210	COG5002	protein histidine kinase activity
MYO_124240	COG2211	Major facilitator Superfamily
MYO_124270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MYO_124280	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MYO_12430	COG0484	heat shock protein binding
MYO_124320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MYO_124330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MYO_124350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MYO_124370	COG0745	RESPONSE REGULATOR receiver
MYO_124380	COG0406	alpha-ribazole phosphatase activity
MYO_12440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MYO_124400	COG0475	glutathione-regulated potassium exporter activity
MYO_124400	COG0589	response to stress
MYO_124420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MYO_124440	COG1122	ATPase activity
MYO_124460	COG0310	cobalt ion transport
MYO_124520	COG0438	transferase activity, transferring glycosyl groups
MYO_124530	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MYO_124560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MYO_124570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MYO_124590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MYO_12460	COG1216	Glycosyl transferase, family 2
MYO_12460	COG0463	Glycosyl transferase, family 2
MYO_124610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MYO_124630	COG1598	PFAM Uncharacterised protein family UPF0150
MYO_124650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MYO_124670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MYO_124680	COG0302	gtp cyclohydrolase
MYO_124690	COG1058	Belongs to the CinA family
MYO_124690	COG1546	Belongs to the CinA family
MYO_124700	COG0792	nuclease activity
MYO_124720	COG2385	sporulation resulting in formation of a cellular spore
MYO_124720	COG2247	cell wall binding repeat
MYO_124730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MYO_124750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MYO_12480	COG1605	Chorismate mutase
MYO_12480	COG0077	Prephenate dehydratase
MYO_124800	COG0121	glutamine amidotransferase
MYO_124810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MYO_124820	COG2048	Heterodisulfide reductase, subunit B
MYO_124830	COG0762	integral membrane protein
MYO_124860	COG4178	(ABC) transporter
MYO_124900	COG0824	Thioesterase
MYO_124910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MYO_124960	COG2205	protein histidine kinase activity
MYO_124960	COG2202	Pas domain
MYO_124990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MYO_1250	COG0848	biopolymer transport protein
MYO_12500	COG2203	Gaf domain
MYO_12500	COG3706	GGDEF domain
MYO_12500	COG4251	negative regulation of phosphorylation
MYO_12500	COG5001	Diguanylate cyclase
MYO_125000	COG0646	methionine synthase
MYO_125000	COG1410	methionine synthase
MYO_125040	COG1410	methionine synthase
MYO_125040	COG0646	methionine synthase
MYO_125070	COG1309	transcriptional regulator
MYO_125080	COG0534	Mate efflux family protein
MYO_125110	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MYO_125120	COG0303	'Molybdopterin
MYO_125130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MYO_125140	COG0315	cyclic pyranopterin monophosphate synthase activity
MYO_125140	COG0746	molybdenum cofactor guanylyltransferase activity
MYO_125160	COG0314	molybdopterin synthase activity
MYO_125180	COG0606	chelatase, subunit chli
MYO_125190	COG1032	radical SAM domain protein
MYO_12520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MYO_125270	COG0156	8-amino-7-oxononanoate synthase activity
MYO_125280	COG0024	Methionine aminopeptidase
MYO_125300	COG0494	nUDIX hydrolase
MYO_125310	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MYO_125320	COG0039	L-malate dehydrogenase activity
MYO_125350	COG0193	aminoacyl-tRNA hydrolase activity
MYO_125390	COG3263	regulation of cellular component size
MYO_125410	COG0024	Methionine aminopeptidase
MYO_125420	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
MYO_125450	COG4243	Vitamin k epoxide reductase
MYO_125460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MYO_125460	COG0426	domain, Protein
MYO_125470	COG0613	PHP domain protein
MYO_125480	COG2251	uridine kinase activity
MYO_125490	COG3063	Type IV pilus biogenesis stability protein PilW
MYO_125500	COG0023	Translation Initiation Factor
MYO_125590	COG2124	cytochrome p450
MYO_125610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MYO_125640	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MYO_125670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MYO_125690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MYO_125710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MYO_125720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MYO_125730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MYO_125740	COG5001	Diguanylate cyclase
MYO_125740	COG3706	GGDEF domain
MYO_125740	COG4251	negative regulation of phosphorylation
MYO_125740	COG2203	Gaf domain
MYO_125750	COG0659	secondary active sulfate transmembrane transporter activity
MYO_125760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MYO_125790	COG1372	Participates in initiation and elongation during chromosome replication
MYO_125790	COG0305	Participates in initiation and elongation during chromosome replication
MYO_12580	COG0589	response to stress
MYO_125800	COG0714	Associated with various cellular activities
MYO_125830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MYO_125840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MYO_125850	COG2226	methyltransferase
MYO_125860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MYO_125870	COG0154	amidase activity
MYO_12590	COG2226	methyltransferase
MYO_125900	COG3706	GGDEF domain
MYO_125900	COG2203	Gaf domain
MYO_125900	COG4251	negative regulation of phosphorylation
MYO_125900	COG5001	Diguanylate cyclase
MYO_125930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MYO_125960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MYO_125980	COG1959	2 iron, 2 sulfur cluster binding
MYO_125990	COG3706	GGDEF domain
MYO_125990	COG5001	Diguanylate cyclase
MYO_125990	COG2203	Gaf domain
MYO_125990	COG4251	negative regulation of phosphorylation
MYO_1260	COG0811	peptide transport
MYO_126000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MYO_126020	COG0357	Ribosomal RNA small subunit methyltransferase G
MYO_126050	COG0719	Fe-S assembly protein
MYO_126060	COG0396	ATPase activity
MYO_126070	COG0719	Fe-S assembly protein
MYO_126080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MYO_126090	COG0003	Pfam Anion-transporting ATPase
MYO_12610	COG0538	isocitrate dehydrogenase activity
MYO_126120	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MYO_126130	COG0720	synthase
MYO_126160	COG0328	RNA-DNA hybrid ribonuclease activity
MYO_126170	COG0745	RESPONSE REGULATOR receiver
MYO_126180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MYO_126190	COG0513	Belongs to the DEAD box helicase family
MYO_12620	COG4636	protein conserved in cyanobacteria
MYO_126200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MYO_126210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MYO_126220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MYO_126230	COG0443	Heat shock 70 kDa protein
MYO_126250	COG2226	methyltransferase
MYO_126260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MYO_126270	COG1012	belongs to the aldehyde dehydrogenase family
MYO_126280	COG1216	Glycosyl transferase, family 2
MYO_126290	COG0484	heat shock protein binding
MYO_126310	COG0659	secondary active sulfate transmembrane transporter activity
MYO_126330	COG1131	(ABC) transporter
MYO_126340	COG0131	Imidazoleglycerol-phosphate dehydratase
MYO_126360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MYO_126370	COG4251	negative regulation of phosphorylation
MYO_126380	COG2197	response regulator
MYO_12640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_126410	COG0515	serine threonine protein kinase
MYO_126430	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_126460	COG0436	Aminotransferase
MYO_126470	COG0586	Pfam SNARE associated Golgi protein
MYO_126480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MYO_126480	COG3264	Mechanosensitive ion channel
MYO_126510	COG0848	biopolymer transport protein
MYO_126520	COG0848	biopolymer transport protein
MYO_126530	COG0811	peptide transport
MYO_126540	COG1840	ABC-type Fe3 transport system, periplasmic component
MYO_126560	COG1357	PFAM Pentapeptide repeats (8 copies)
MYO_126570	COG2205	protein histidine kinase activity
MYO_126590	COG0456	acetyltransferase
MYO_126610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MYO_126620	COG0047	phosphoribosylformylglycinamidine synthase activity
MYO_126670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MYO_126680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MYO_126690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MYO_12670	COG0762	integral membrane protein
MYO_126700	COG0628	permease
MYO_126730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MYO_126740	COG0837	glucose binding
MYO_126750	COG1132	(ABC) transporter
MYO_126790	COG0668	transmembrane transport
MYO_12680	COG1840	ABC-type Fe3 transport system, periplasmic component
MYO_126800	COG1492	cobalamin metabolic process
MYO_126840	COG0469	pyruvate kinase activity
MYO_126850	COG2081	HI0933 family
MYO_126860	COG3118	belongs to the thioredoxin family
MYO_126890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MYO_12690	COG0336	Belongs to the RNA methyltransferase TrmD family
MYO_126920	COG0457	Tetratricopeptide repeat
MYO_126920	COG0463	Glycosyl transferase, family 2
MYO_126940	COG0004	ammonium transporteR
MYO_126950	COG0800	Aldolase
MYO_126970	COG1480	7TM receptor with intracellular HD hydrolase
MYO_126980	COG2304	oxidoreductase activity
MYO_127000	COG1192	Involved in chromosome partitioning
MYO_127030	COG1473	amidohydrolase
MYO_127050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MYO_12710	COG0205	6-phosphofructokinase activity
MYO_127100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MYO_127110	COG2205	protein histidine kinase activity
MYO_127110	COG0784	Response regulator, receiver
MYO_127120	COG1192	Involved in chromosome partitioning
MYO_127160	COG0745	RESPONSE REGULATOR receiver
MYO_12720	COG1289	transmembrane transporter activity
MYO_127200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MYO_127220	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MYO_127240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MYO_127250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MYO_127260	COG2894	cell division
MYO_127270	COG0850	regulation of cytokinetic process
MYO_127280	COG1716	ATPase activity
MYO_12730	COG1555	photosystem II stabilization
MYO_127310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MYO_127310	COG0574	Belongs to the PEP-utilizing enzyme family
MYO_127320	COG0745	RESPONSE REGULATOR receiver
MYO_127320	COG3706	GGDEF domain
MYO_127350	COG0398	Pfam SNARE associated Golgi protein
MYO_127360	COG0737	Belongs to the 5'-nucleotidase family
MYO_127370	COG0454	-acetyltransferase
MYO_127400	COG1032	radical SAM domain protein
MYO_127440	COG4585	Histidine kinase
MYO_127450	COG2197	response regulator
MYO_127460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MYO_127460	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MYO_127470	COG2267	carboxylic ester hydrolase activity
MYO_127480	COG4221	oxidoreductase activity
MYO_12750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MYO_127540	COG0024	Methionine aminopeptidase
MYO_127560	COG1056	cytidyltransferase-related domain
MYO_127560	COG1051	belongs to the nudix hydrolase family
MYO_127590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MYO_12760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MYO_127600	COG5002	protein histidine kinase activity
MYO_127650	COG2814	Major facilitator Superfamily
MYO_127670	COG2217	Heavy metal translocating P-type atpase
MYO_127680	COG1742	UPF0060 membrane protein
MYO_127690	COG0640	Transcriptional regulator
MYO_12770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MYO_127700	COG2217	Heavy metal translocating P-type atpase
MYO_127710	COG5002	protein histidine kinase activity
MYO_127720	COG0745	RESPONSE REGULATOR receiver
MYO_127770	COG2144	transferase activity, transferring acyl groups
MYO_127820	COG2072	flavoprotein involved in K transport
MYO_127830	COG2197	response regulator
MYO_127860	COG5001	Diguanylate cyclase
MYO_127860	COG3706	GGDEF domain
MYO_127860	COG2203	Gaf domain
MYO_127860	COG4251	negative regulation of phosphorylation
MYO_127870	COG0842	Transport permease protein
MYO_127870	COG1131	(ABC) transporter
MYO_127870	COG1716	ATPase activity
MYO_127890	COG0515	serine threonine protein kinase
MYO_127890	COG3064	Membrane
MYO_127890	COG4991	sh3 domain protein
MYO_127910	COG0401	homolog of Blt101
MYO_127960	COG0789	Transcriptional regulator
MYO_128070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MYO_128080	COG0598	Magnesium transport protein CorA
MYO_128110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MYO_128110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MYO_128180	COG0251	oxidation-reduction process
MYO_128190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MYO_12820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MYO_128200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MYO_128210	COG0392	lysyltransferase activity
MYO_128250	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MYO_128270	COG0343	queuine tRNA-ribosyltransferase activity
MYO_12830	COG0277	FAD linked oxidase domain protein
MYO_128300	COG2886	Uncharacterised protein family (UPF0175)
MYO_128310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MYO_128320	COG0668	transmembrane transport
MYO_128330	COG0205	6-phosphofructokinase activity
MYO_128370	COG1013	pyruvate-flavodoxin oxidoreductase activity
MYO_128370	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MYO_128370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MYO_128370	COG0674	pyruvate-flavodoxin oxidoreductase activity
MYO_128390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MYO_128400	COG0725	ABC transporter, periplasmic molybdate-binding protein
MYO_128450	COG0438	transferase activity, transferring glycosyl groups
MYO_128490	COG0840	transmembrane signaling receptor activity
MYO_128500	COG0840	transmembrane signaling receptor activity
MYO_128500	COG2203	Gaf domain
MYO_128530	COG0784	Response regulator, receiver
MYO_128550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MYO_128560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MYO_128570	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MYO_128580	COG1597	lipid kinase activity
MYO_128580	COG1803	Methylglyoxal synthase
MYO_128640	COG0857	belongs to the CobB CobQ family
MYO_128650	COG0583	DNA-binding transcription factor activity
MYO_128660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MYO_128670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MYO_128680	COG3659	wide pore channel activity
MYO_128690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MYO_128690	COG1116	anion transmembrane transporter activity
MYO_12870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MYO_128700	COG1116	anion transmembrane transporter activity
MYO_128720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MYO_128740	COG0724	RNA recognition motif
MYO_128750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MYO_128760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MYO_128770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MYO_128780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MYO_128790	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MYO_128800	COG1653	transport
MYO_128810	COG1175	transmembrane transport
MYO_128820	COG0395	ABC-type sugar transport system, permease component
MYO_128840	COG2205	protein histidine kinase activity
MYO_128870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MYO_12890	COG0408	coproporphyrinogen oxidase activity
MYO_128900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MYO_128910	COG0598	Magnesium transport protein CorA
MYO_128920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MYO_128930	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MYO_128940	COG0019	diaminopimelate decarboxylase activity
MYO_128950	COG1160	GTP binding
MYO_128960	COG0018	arginyl-trna synthetase
MYO_128970	COG0463	Glycosyl transferase, family 2
MYO_128990	COG0740	serine-type endopeptidase activity
MYO_1290	COG1132	(ABC) transporter
MYO_12900	COG5398	heme oxygenase
MYO_129000	COG0133	tryptophan synthase activity
MYO_129020	COG1136	(ABC) transporter
MYO_129030	COG2314	TM2 domain
MYO_129070	COG0017	Asparaginyl-tRNA synthetase
MYO_129110	COG0569	domain protein
MYO_129120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MYO_129130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MYO_129140	COG0629	single-stranded DNA binding
MYO_129150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MYO_129170	COG1192	Involved in chromosome partitioning
MYO_129190	COG2119	membrane
MYO_12920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MYO_129200	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MYO_129210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MYO_129230	COG1162	GTPase activity
MYO_129250	COG0484	heat shock protein binding
MYO_129260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MYO_129270	COG1218	3'(2'),5'-bisphosphate nucleotidase
MYO_129280	COG0134	indole-3-glycerol-phosphate synthase activity
MYO_129290	COG0004	ammonium transporteR
MYO_129300	COG0569	domain protein
MYO_129310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MYO_129320	COG0740	serine-type endopeptidase activity
MYO_129330	COG0544	peptidyl-prolyl cis-trans isomerase activity
MYO_129340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MYO_129350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MYO_129360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MYO_129380	COG0237	dephospho-CoA kinase activity
MYO_129410	COG0517	IMP dehydrogenase activity
MYO_129410	COG1994	Peptidase M50
MYO_129420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MYO_129460	COG0525	valine-tRNA ligase activity
MYO_129470	COG0713	ATP synthesis coupled electron transport
MYO_129480	COG0839	Belongs to the complex I subunit 6 family
MYO_129490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_129500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MYO_129510	COG0167	dihydroorotate dehydrogenase activity
MYO_129520	COG2166	iron-sulfur cluster assembly
MYO_129530	COG1070	Carbohydrate kinase
MYO_129560	COG0308	aminopeptidase N
MYO_129570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MYO_129580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MYO_129590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MYO_12960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MYO_129610	COG2193	ferroxidase activity
MYO_129630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MYO_129650	COG1834	amidinotransferase
MYO_129660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MYO_12970	COG0672	)-iron permease
MYO_129720	COG0745	RESPONSE REGULATOR receiver
MYO_129730	COG0483	inositol monophosphate 1-phosphatase activity
MYO_129760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MYO_129770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MYO_129780	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MYO_129790	COG4208	sulfate ABC transporter
MYO_12980	COG0592	DNA-directed DNA polymerase activity
MYO_129800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MYO_129810	COG2165	general secretion pathway protein
MYO_129840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MYO_129870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MYO_129880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MYO_129890	COG0731	radical SAM domain protein
MYO_12990	COG0159	tryptophan synthase activity
MYO_129900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MYO_129910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MYO_129930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MYO_129940	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MYO_129970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MYO_130080	COG0339	signal peptide processing
MYO_130090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MYO_130130	COG1166	arginine decarboxylase activity
MYO_130150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MYO_130190	COG1049	propionate catabolic process, 2-methylcitrate cycle
MYO_13020	COG0436	Aminotransferase
MYO_130230	COG0070	glutamate synthase
MYO_130230	COG0067	glutamate synthase
MYO_130230	COG0069	glutamate synthase activity
MYO_130240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MYO_130250	COG0505	Belongs to the CarA family
MYO_130270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MYO_130280	COG0579	oxidoreductase
MYO_130300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MYO_130310	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MYO_130320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MYO_130340	COG1191	sigma factor activity
MYO_130350	COG0316	Belongs to the HesB IscA family
MYO_130360	COG0463	Glycosyl transferase, family 2
MYO_130370	COG2319	Wd-40 repeat
MYO_13040	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MYO_130400	COG1691	(AIR) carboxylase
MYO_130410	COG0739	heme binding
MYO_130460	COG2052	Domain of unknown function (DUF370)
MYO_130470	COG3264	Mechanosensitive ion channel
MYO_130470	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MYO_130540	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MYO_130570	COG0363	glucosamine-6-phosphate deaminase activity
MYO_130610	COG2205	protein histidine kinase activity
MYO_130620	COG5001	Diguanylate cyclase
MYO_130620	COG3706	GGDEF domain
MYO_130620	COG2203	Gaf domain
MYO_130620	COG4251	negative regulation of phosphorylation
MYO_130640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MYO_130680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MYO_130690	COG5001	Diguanylate cyclase
MYO_130690	COG3300	MHYT domain
MYO_13070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MYO_130710	COG3842	ATPase activity
MYO_130730	COG1543	Belongs to the glycosyl hydrolase 57 family
MYO_130750	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MYO_130760	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MYO_130780	COG0457	Tetratricopeptide repeat
MYO_130790	COG0148	phosphopyruvate hydratase activity
MYO_130810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MYO_130840	COG0825	malonyl-CoA metabolic process
MYO_130870	COG1598	PFAM Uncharacterised protein family UPF0150
MYO_13090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MYO_130910	COG4251	negative regulation of phosphorylation
MYO_130920	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MYO_130960	COG2994	toxin metabolic process
MYO_130990	COG0170	dolichyl monophosphate biosynthetic process
MYO_13100	COG0701	Predicted permease
MYO_131000	COG1473	amidohydrolase
MYO_131010	COG3659	wide pore channel activity
MYO_131050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MYO_131060	COG2203	Gaf domain
MYO_131060	COG3706	GGDEF domain
MYO_131060	COG4251	negative regulation of phosphorylation
MYO_131060	COG5001	Diguanylate cyclase
MYO_131100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MYO_131150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MYO_131180	COG2197	response regulator
MYO_131240	COG2153	protein acetylation
MYO_131340	COG4581	dead DEAH box helicase
MYO_131360	COG0322	excinuclease ABC activity
MYO_131370	COG0129	dihydroxy-acid dehydratase activity
MYO_131380	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MYO_13140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MYO_131440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MYO_131450	COG0546	phosphoglycolate phosphatase activity
MYO_13150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MYO_131510	COG0326	Molecular chaperone. Has ATPase activity
MYO_131520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MYO_131550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MYO_131560	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MYO_131580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MYO_13160	COG4636	protein conserved in cyanobacteria
MYO_131630	COG0723	plastoquinol--plastocyanin reductase activity
MYO_131660	COG1842	Phage shock protein A
MYO_13170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MYO_131700	COG1064	alcohol dehydrogenase
MYO_131710	COG0137	argininosuccinate synthase activity
MYO_131740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MYO_131790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MYO_131820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MYO_131830	COG0549	Belongs to the carbamate kinase family
MYO_131860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MYO_131870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MYO_131880	COG1136	(ABC) transporter
MYO_131880	COG0577	efflux transmembrane transporter activity
MYO_131890	COG0735	belongs to the Fur family
MYO_131910	COG0138	bifunctional purine biosynthesis protein purh
MYO_131950	COG0515	serine threonine protein kinase
MYO_1320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MYO_132000	COG0587	DNA-directed DNA polymerase activity
MYO_132010	COG0481	GTPase activity
MYO_132020	COG0435	Glutathione S-transferase
MYO_132050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MYO_132050	COG0140	phosphoribosyl-ATP diphosphatase activity
MYO_132060	COG0523	cobalamin synthesis protein
MYO_13210	COG0489	protein tyrosine kinase activity
MYO_13210	COG3206	protein involved in exopolysaccharide biosynthesis
MYO_13290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MYO_1330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MYO_13370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MYO_13380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MYO_13390	COG1088	dTDP-glucose 4,6-dehydratase activity
MYO_13400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MYO_13430	COG1215	transferase activity, transferring glycosyl groups
MYO_13450	COG1215	transferase activity, transferring glycosyl groups
MYO_13460	COG0438	transferase activity, transferring glycosyl groups
MYO_1350	COG1132	(ABC) transporter
MYO_13510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MYO_13560	COG0297	glycogen (starch) synthase activity
MYO_13570	COG0438	transferase activity, transferring glycosyl groups
MYO_13580	COG1598	PFAM Uncharacterised protein family UPF0150
MYO_13600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MYO_13660	COG0110	maltose O-acetyltransferase activity
MYO_13690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MYO_13710	COG3781	membrane
MYO_13720	COG0045	succinate-CoA ligase (ADP-forming) activity
MYO_13730	COG0861	Integral membrane protein TerC family
MYO_13740	COG2268	Band 7 protein
MYO_13750	COG0463	Glycosyl transferase, family 2
MYO_13760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MYO_13780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MYO_13790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MYO_13800	COG0004	ammonium transporteR
MYO_13810	COG0745	RESPONSE REGULATOR receiver
MYO_13840	COG0737	Belongs to the 5'-nucleotidase family
MYO_13850	COG0529	Catalyzes the synthesis of activated sulfate
MYO_13860	COG0811	peptide transport
MYO_13870	COG0848	biopolymer transport protein
MYO_13880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MYO_13880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MYO_13900	COG0530	calcium, potassium:sodium antiporter activity
MYO_13940	COG0745	RESPONSE REGULATOR receiver
MYO_13950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MYO_140	COG0515	serine threonine protein kinase
MYO_14010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MYO_14020	COG2203	Gaf domain
MYO_14020	COG5001	Diguanylate cyclase
MYO_14020	COG3706	GGDEF domain
MYO_14020	COG4251	negative regulation of phosphorylation
MYO_14040	COG0471	metal ion transport
MYO_14040	COG3273	potassium ion transport
MYO_14100	COG3854	ATPases associated with a variety of cellular activities
MYO_14110	COG0352	thiamine-phosphate diphosphorylase activity
MYO_14120	COG0434	BtpA family
MYO_14170	COG0564	pseudouridine synthase activity
MYO_14180	COG4251	negative regulation of phosphorylation
MYO_14180	COG3706	GGDEF domain
MYO_14180	COG2203	Gaf domain
MYO_14180	COG5001	Diguanylate cyclase
MYO_14200	COG0475	glutathione-regulated potassium exporter activity
MYO_14260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MYO_14270	COG1733	regulation of RNA biosynthetic process
MYO_14280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MYO_14360	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MYO_14390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MYO_1440	COG0409	Hydrogenase expression formation protein
MYO_14410	COG1487	ribonuclease activity
MYO_14440	COG2361	Protein of unknown function DUF86
MYO_14470	COG0067	glutamate synthase
MYO_14470	COG0069	glutamate synthase activity
MYO_14470	COG0070	glutamate synthase
MYO_1450	COG1091	dTDP-4-dehydrorhamnose reductase activity
MYO_14510	COG2133	pyrroloquinoline quinone binding
MYO_14520	COG1797	cobyrinic acid a,c-diamide synthase activity
MYO_14530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MYO_14540	COG1022	Amp-dependent synthetase and ligase
MYO_14550	COG0784	Response regulator, receiver
MYO_14580	COG0840	transmembrane signaling receptor activity
MYO_14580	COG2203	Gaf domain
MYO_14590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MYO_1460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MYO_14600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MYO_14610	COG2203	Gaf domain
MYO_14610	COG3706	GGDEF domain
MYO_14610	COG5001	Diguanylate cyclase
MYO_14610	COG4251	negative regulation of phosphorylation
MYO_14620	COG0419	ATPase involved in DNA repair
MYO_14630	COG0484	heat shock protein binding
MYO_14640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MYO_14660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MYO_1470	COG0297	glycogen (starch) synthase activity
MYO_14700	COG1429	ligase activity, forming nitrogen-metal bonds
MYO_14730	COG3956	TIGRFAM MazG family protein
MYO_14750	COG5002	protein histidine kinase activity
MYO_14800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MYO_14830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MYO_14840	COG1247	-acetyltransferase
MYO_14850	COG0174	glutamine synthetase
MYO_14870	COG3706	GGDEF domain
MYO_14870	COG2203	Gaf domain
MYO_14870	COG5001	Diguanylate cyclase
MYO_14870	COG4251	negative regulation of phosphorylation
MYO_14890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MYO_14900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MYO_14930	COG2310	stress, protein
MYO_14940	COG0076	glutamate decarboxylase activity
MYO_14970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MYO_14980	COG0829	nickel cation binding
MYO_150	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MYO_1500	COG1131	(ABC) transporter
MYO_15010	COG1045	serine acetyltransferase
MYO_15040	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MYO_15070	COG0271	Belongs to the BolA IbaG family
MYO_15080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MYO_15090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MYO_15130	COG0804	urea catabolic process
MYO_15150	COG1357	PFAM Pentapeptide repeats (8 copies)
MYO_15190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MYO_15200	COG1773	rubredoxin
MYO_15210	COG4447	cellulose binding
MYO_15260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MYO_15280	COG3385	transposase activity
MYO_1530	COG2318	DinB family
MYO_15320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MYO_15340	COG3228	Belongs to the MtfA family
MYO_15410	COG1121	(ABC) transporter
MYO_15420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MYO_15450	COG1702	phosphate starvation-inducible protein PhoH
MYO_15480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MYO_15520	COG0484	heat shock protein binding
MYO_15530	COG0443	Heat shock 70 kDa protein
MYO_15540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MYO_15590	COG3659	wide pore channel activity
MYO_15610	COG0860	N-Acetylmuramoyl-L-alanine amidase
MYO_15610	COG2247	cell wall binding repeat
MYO_1570	COG1214	PFAM Peptidase M22, glycoprotease
MYO_15730	COG0768	penicillin binding
MYO_15750	COG0247	lactate metabolic process
MYO_15770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MYO_15790	COG0583	DNA-binding transcription factor activity
MYO_15810	COG0384	phenazine biosynthesis protein PhzF
MYO_15830	COG2319	Wd-40 repeat
MYO_15840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MYO_15890	COG0475	glutathione-regulated potassium exporter activity
MYO_15890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MYO_15900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MYO_15940	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MYO_15950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MYO_15980	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MYO_15990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MYO_160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MYO_16020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MYO_16030	COG0629	single-stranded DNA binding
MYO_16060	COG0668	transmembrane transport
MYO_16080	COG0745	RESPONSE REGULATOR receiver
MYO_16090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MYO_16090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MYO_1610	COG1615	UPF0182 protein
MYO_16100	COG3937	granule-associated protein
MYO_16130	COG2226	methyltransferase
MYO_16150	COG0681	Belongs to the peptidase S26 family
MYO_16170	COG1271	oxidase subunit
MYO_16180	COG1294	oxidase, subunit
MYO_16190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MYO_16200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MYO_16210	COG0412	Dienelactone hydrolase
MYO_16310	COG0840	transmembrane signaling receptor activity
MYO_16310	COG2203	Gaf domain
MYO_16340	COG0784	Response regulator, receiver
MYO_16350	COG0557	exoribonuclease II activity
MYO_16370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MYO_1640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MYO_16400	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MYO_16420	COG5002	protein histidine kinase activity
MYO_16430	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MYO_16440	COG1309	transcriptional regulator
MYO_16490	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MYO_1650	COG0563	adenylate kinase activity
MYO_16510	COG2385	sporulation resulting in formation of a cellular spore
MYO_16530	COG3411	Ferredoxin
MYO_16540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MYO_16590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MYO_1660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MYO_16600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MYO_16610	COG0237	dephospho-CoA kinase activity
MYO_16620	COG0237	dephospho-CoA kinase activity
MYO_16670	COG0515	serine threonine protein kinase
MYO_16690	COG2988	succinylglutamate desuccinylase activity
MYO_16700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MYO_16720	COG0739	heme binding
MYO_16730	COG0587	DNA-directed DNA polymerase activity
MYO_16760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MYO_1680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MYO_16820	COG1006	Multisubunit Na H antiporter MnhC subunit
MYO_16970	COG1132	(ABC) transporter
MYO_16980	COG3063	Type IV pilus biogenesis stability protein PilW
MYO_16990	COG2217	Heavy metal translocating P-type atpase
MYO_170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MYO_17000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MYO_17010	COG0745	RESPONSE REGULATOR receiver
MYO_17030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MYO_17040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MYO_17060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MYO_1710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MYO_17120	COG0557	exoribonuclease II activity
MYO_17140	COG2208	phosphoserine phosphatase activity
MYO_17150	COG0165	Argininosuccinate lyase
MYO_17160	COG2816	NAD+ diphosphatase activity
MYO_17190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MYO_1720	COG0194	GDP metabolic process
MYO_17200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MYO_17210	COG1845	cytochrome c oxidase, subunit III
MYO_17220	COG3118	belongs to the thioredoxin family
MYO_17240	COG1116	anion transmembrane transporter activity
MYO_17250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MYO_17280	COG0375	protein maturation
MYO_17290	COG0010	Belongs to the arginase family
MYO_1730	COG0406	alpha-ribazole phosphatase activity
MYO_17310	COG3706	GGDEF domain
MYO_17320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MYO_17330	COG0495	leucyl-tRNA aminoacylation
MYO_17340	COG0786	glutamate:sodium symporter activity
MYO_17350	COG2205	protein histidine kinase activity
MYO_17370	COG1132	(ABC) transporter
MYO_17410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MYO_17420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MYO_17430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MYO_17480	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MYO_17490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MYO_1750	COG0730	response to heat
MYO_17510	COG0254	rRNA binding
MYO_17520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MYO_17530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MYO_17540	COG0101	tRNA pseudouridine synthase activity
MYO_17550	COG0203	ribosomal protein L17
MYO_17560	COG0202	RNA polymerase activity
MYO_17570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MYO_17580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MYO_17590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MYO_1760	COG1413	lyase activity
MYO_17600	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MYO_17610	COG0563	adenylate kinase activity
MYO_17620	COG0201	protein transport
MYO_17630	COG0200	Binds to the 23S rRNA
MYO_17640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MYO_17650	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MYO_17660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MYO_17670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MYO_17680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MYO_17690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MYO_17700	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MYO_17710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MYO_17720	COG0255	Belongs to the universal ribosomal protein uL29 family
MYO_17730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MYO_17740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MYO_17750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MYO_17760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MYO_17770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MYO_17780	COG0089	rRNA binding
MYO_17790	COG0088	Forms part of the polypeptide exit tunnel
MYO_17800	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MYO_17810	COG0783	Belongs to the Dps family
MYO_17850	COG2010	Cytochrome c
MYO_17870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MYO_17880	COG0830	nickel cation binding
MYO_1790	COG0330	HflC and HflK could
MYO_17900	COG1131	(ABC) transporter
MYO_17950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MYO_17960	COG0085	RNA polymerase activity
MYO_17970	COG0084	hydrolase, TatD family'
MYO_17980	COG0268	Binds directly to 16S ribosomal RNA
MYO_17990	COG5002	protein histidine kinase activity
MYO_1800	COG1530	ribonuclease E activity
MYO_18010	COG0210	DNA helicase
MYO_18010	COG0210	DNA helicase
MYO_18020	COG1196	nuclear chromosome segregation
MYO_18030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MYO_18070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MYO_18070	COG0758	DNA mediated transformation
MYO_18080	COG0393	Putative heavy-metal-binding
MYO_1810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MYO_18100	COG0450	alkyl hydroperoxide reductase
MYO_18110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MYO_18120	COG0559	Belongs to the binding-protein-dependent transport system permease family
MYO_18140	COG1175	transmembrane transport
MYO_18160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MYO_1820	COG0494	nUDIX hydrolase
MYO_18210	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_18210	COG3347	Dehydrogenase
MYO_18250	COG5001	Diguanylate cyclase
MYO_18250	COG2203	Gaf domain
MYO_18250	COG4251	negative regulation of phosphorylation
MYO_18250	COG3706	GGDEF domain
MYO_18260	COG0745	RESPONSE REGULATOR receiver
MYO_18270	COG0784	Response regulator, receiver
MYO_18290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MYO_1830	COG1185	polyribonucleotide nucleotidyltransferase activity
MYO_18300	COG2239	Acts as a magnesium transporter
MYO_18360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MYO_18370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MYO_18380	COG1799	cell septum assembly
MYO_18390	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MYO_18390	COG0662	Cupin 2, conserved barrel domain protein
MYO_1840	COG0681	Belongs to the peptidase S26 family
MYO_18410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MYO_18420	COG0459	protein refolding
MYO_18460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MYO_18470	COG0222	ribosome binding
MYO_18480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MYO_18490	COG0081	regulation of translation
MYO_18500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MYO_18510	COG0250	Participates in transcription elongation, termination and antitermination
MYO_18520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MYO_18540	COG0335	large ribosomal subunit rRNA binding
MYO_18600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MYO_18620	COG3243	poly(R)-hydroxyalkanoic acid synthase
MYO_18640	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MYO_18660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MYO_18670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MYO_18690	COG2885	chlorophyll binding
MYO_1870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MYO_18700	COG2885	chlorophyll binding
MYO_18720	COG1132	(ABC) transporter
MYO_18740	COG0438	transferase activity, transferring glycosyl groups
MYO_18760	COG0745	RESPONSE REGULATOR receiver
MYO_18770	COG0508	dehydrogenase complex catalyzes the overall conversion of
MYO_18770	COG0022	dehydrogenase e1 component
MYO_18780	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MYO_18790	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MYO_18800	COG1929	Belongs to the glycerate kinase type-1 family
MYO_18810	COG3659	wide pore channel activity
MYO_18820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MYO_18830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MYO_18840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MYO_1890	COG1401	restriction endodeoxyribonuclease activity
MYO_18900	COG0776	regulation of translation
MYO_18930	COG0514	ATP-dependent DNA helicase (RecQ)
MYO_18950	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MYO_18960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MYO_18980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MYO_190	COG1166	arginine decarboxylase activity
MYO_1900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MYO_19070	COG0438	transferase activity, transferring glycosyl groups
MYO_19080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MYO_19090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MYO_1910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MYO_19100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MYO_19130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MYO_19140	COG0242	peptide deformylase activity
MYO_19160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MYO_19210	COG0243	molybdopterin cofactor binding
MYO_19220	COG1116	anion transmembrane transporter activity
MYO_19230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MYO_19230	COG1116	anion transmembrane transporter activity
MYO_19240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MYO_19250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MYO_19280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MYO_19290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MYO_19310	COG0793	Belongs to the peptidase S41A family
MYO_19330	COG0275	rRNA processing
MYO_19350	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MYO_19400	COG1090	epimerase
MYO_19420	COG0515	serine threonine protein kinase
MYO_19440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MYO_19450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MYO_19460	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MYO_19470	COG0659	secondary active sulfate transmembrane transporter activity
MYO_19480	COG0589	response to stress
MYO_19490	COG1233	COG1233 Phytoene dehydrogenase and related
MYO_19520	COG1053	succinate dehydrogenase
MYO_19530	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MYO_19540	COG0537	adenosine 5'-monophosphoramidase activity
MYO_19600	COG0402	S-adenosylhomocysteine deaminase activity
MYO_19630	COG2267	carboxylic ester hydrolase activity
MYO_19650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MYO_19660	COG0189	ligase activity
MYO_19680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MYO_19690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MYO_19730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MYO_19740	COG0312	modulator of DNA gyrase
MYO_19780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MYO_19800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MYO_19800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MYO_19830	COG2140	Oxalate decarboxylase
MYO_19840	COG0058	SHG alpha-glucan phosphorylase activity
MYO_19880	COG0515	serine threonine protein kinase
MYO_19920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MYO_19920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MYO_19930	COG3850	Histidine kinase
MYO_19930	COG3437	response regulator, receiver
MYO_19930	COG2205	protein histidine kinase activity
MYO_19930	COG4999	Histidine kinase
MYO_19990	COG0546	phosphoglycolate phosphatase activity
MYO_21060	COG1192	Involved in chromosome partitioning
MYO_21230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MYO_21240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MYO_2190	COG2361	Protein of unknown function DUF86
MYO_2220	COG3093	addiction module antidote protein HigA
MYO_2230	COG1104	cysteine desulfurase activity
MYO_2370	COG0446	pyridine nucleotide-disulphide oxidoreductase
MYO_2420	COG3328	transposase activity
MYO_2490	COG0438	transferase activity, transferring glycosyl groups
MYO_2510	COG0438	transferase activity, transferring glycosyl groups
MYO_2580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MYO_2600	COG3706	GGDEF domain
MYO_2600	COG0745	RESPONSE REGULATOR receiver
MYO_2610	COG5002	protein histidine kinase activity
MYO_2610	COG2205	protein histidine kinase activity
MYO_2610	COG0784	Response regulator, receiver
MYO_2770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MYO_2800	COG1028	Short-chain dehydrogenase reductase Sdr
MYO_2820	COG3878	Protein conserved in bacteria
MYO_2870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MYO_310	COG5001	Diguanylate cyclase
MYO_31010	COG4680	protein conserved in bacteria
MYO_31030	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MYO_31040	COG1451	nucleotide metabolic process
MYO_31060	COG3385	transposase activity
MYO_31080	COG2340	Cysteine-rich secretory protein family
MYO_320	COG4191	Histidine kinase
MYO_320	COG0784	Response regulator, receiver
MYO_3370	COG1192	Involved in chromosome partitioning
MYO_3410	COG0745	RESPONSE REGULATOR receiver
MYO_3590	COG2340	Cysteine-rich secretory protein family
MYO_3990	COG3177	Filamentation induced by cAMP protein fic
MYO_41010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MYO_4290	COG4453	Protein conserved in bacteria
MYO_4360	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MYO_4470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MYO_4580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MYO_4690	COG1518	maintenance of DNA repeat elements
MYO_490	COG3385	transposase activity
MYO_4900	COG1518	maintenance of DNA repeat elements
MYO_4900	COG1468	defense response to virus
MYO_5270	COG1846	Transcriptional regulator
MYO_5350	COG2070	2-Nitropropane dioxygenase
MYO_5390	COG2319	Wd-40 repeat
MYO_5390	COG3903	Transcriptional regulator