locus-tag	class	description
SYNPCCP_0001	COG0142	geranyltranstransferase activity
SYNPCCP_0002	COG1187	pseudouridine synthase activity
SYNPCCP_0004	COG0515	serine threonine protein kinase
SYNPCCP_0005	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYNPCCP_0006	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYNPCCP_0007	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SYNPCCP_0009	COG1166	arginine decarboxylase activity
SYNPCCP_0010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYNPCCP_0012	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SYNPCCP_0013	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SYNPCCP_0014	COG1120	ATPase activity
SYNPCCP_0015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SYNPCCP_0017	COG4977	sequence-specific DNA binding
SYNPCCP_0022	COG2207	Transcriptional regulator
SYNPCCP_0023	COG2226	methyltransferase
SYNPCCP_0025	COG0848	biopolymer transport protein
SYNPCCP_0026	COG0811	peptide transport
SYNPCCP_0029	COG1132	(ABC) transporter
SYNPCCP_0032	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SYNPCCP_0033	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SYNPCCP_0035	COG1132	(ABC) transporter
SYNPCCP_0044	COG0409	Hydrogenase expression formation protein
SYNPCCP_0045	COG1091	dTDP-4-dehydrorhamnose reductase activity
SYNPCCP_0046	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYNPCCP_0047	COG0297	glycogen (starch) synthase activity
SYNPCCP_0050	COG1131	(ABC) transporter
SYNPCCP_0053	COG2318	DinB family
SYNPCCP_0057	COG1214	PFAM Peptidase M22, glycoprotease
SYNPCCP_0061	COG1615	UPF0182 protein
SYNPCCP_0064	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SYNPCCP_0065	COG0563	adenylate kinase activity
SYNPCCP_0066	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SYNPCCP_0068	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SYNPCCP_0071	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYNPCCP_0072	COG0194	GDP metabolic process
SYNPCCP_0073	COG0406	alpha-ribazole phosphatase activity
SYNPCCP_0075	COG0730	response to heat
SYNPCCP_0076	COG1413	lyase activity
SYNPCCP_0079	COG0330	HflC and HflK could
SYNPCCP_0080	COG1530	ribonuclease E activity
SYNPCCP_0081	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SYNPCCP_0082	COG0494	nUDIX hydrolase
SYNPCCP_0083	COG1185	polyribonucleotide nucleotidyltransferase activity
SYNPCCP_0084	COG0681	Belongs to the peptidase S26 family
SYNPCCP_0087	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SYNPCCP_0089	COG1401	restriction endodeoxyribonuclease activity
SYNPCCP_0090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SYNPCCP_0091	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SYNPCCP_0100	COG1104	cysteine desulfurase activity
SYNPCCP_0105	COG0582	viral genome integration into host DNA
SYNPCCP_0107	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYNPCCP_0107	COG2022	thiamine diphosphate biosynthetic process
SYNPCCP_0110	COG5002	protein histidine kinase activity
SYNPCCP_0112	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SYNPCCP_0116	COG0704	Plays a role in the regulation of phosphate uptake
SYNPCCP_0117	COG0779	Required for maturation of 30S ribosomal subunits
SYNPCCP_0118	COG0195	Participates in both transcription termination and antitermination
SYNPCCP_0120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SYNPCCP_0128	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYNPCCP_0130	COG0011	TIGRFAM Protein of
SYNPCCP_0131	COG0589	response to stress
SYNPCCP_0133	COG0123	including yeast histone deacetylase and acetoin utilization protein
SYNPCCP_0134	COG0010	Belongs to the arginase family
SYNPCCP_0135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYNPCCP_0142	COG2099	Precorrin-6x reductase
SYNPCCP_0145	COG1007	ATP synthesis coupled electron transport
SYNPCCP_0150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYNPCCP_0151	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SYNPCCP_0152	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYNPCCP_0152	COG0426	domain, Protein
SYNPCCP_0154	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYNPCCP_0154	COG0426	domain, Protein
SYNPCCP_0155	COG0793	Belongs to the peptidase S41A family
SYNPCCP_0156	COG0009	L-threonylcarbamoyladenylate synthase
SYNPCCP_0157	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SYNPCCP_0158	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SYNPCCP_0159	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SYNPCCP_0160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SYNPCCP_0161	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SYNPCCP_0163	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SYNPCCP_0164	COG0356	it plays a direct role in the translocation of protons across the membrane
SYNPCCP_0166	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SYNPCCP_0169	COG0714	Associated with various cellular activities
SYNPCCP_0170	COG0316	Belongs to the HesB IscA family
SYNPCCP_0171	COG0697	spore germination
SYNPCCP_0173	COG1127	ABC transporter
SYNPCCP_0175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SYNPCCP_0179	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SYNPCCP_0182	COG0163	prenyltransferase activity
SYNPCCP_0184	COG0589	response to stress
SYNPCCP_0186	COG5001	Diguanylate cyclase
SYNPCCP_0186	COG1716	ATPase activity
SYNPCCP_0190	COG1234	tRNA 3'-trailer cleavage
SYNPCCP_0192	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SYNPCCP_0195	COG0631	protein serine/threonine phosphatase activity
SYNPCCP_0197	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SYNPCCP_0197	COG4451	ribulose bisphosphate carboxylase, small
SYNPCCP_0198	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SYNPCCP_0199	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNPCCP_0200	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNPCCP_0201	COG0493	'glutamate synthase
SYNPCCP_0211	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYNPCCP_0211	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYNPCCP_0213	COG1982	Orn Lys Arg decarboxylase major
SYNPCCP_0214	COG0686	Belongs to the AlaDH PNT family
SYNPCCP_0215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SYNPCCP_0219	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYNPCCP_0221	COG0673	inositol 2-dehydrogenase activity
SYNPCCP_0222	COG0700	Nucleoside recognition
SYNPCCP_0223	COG2715	membrane protein required for spore maturation
SYNPCCP_0224	COG1640	4-alpha-glucanotransferase
SYNPCCP_0226	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SYNPCCP_0229	COG2203	Gaf domain
SYNPCCP_0229	COG3706	GGDEF domain
SYNPCCP_0229	COG5001	Diguanylate cyclase
SYNPCCP_0229	COG4251	negative regulation of phosphorylation
SYNPCCP_0233	COG0175	sulfate reduction
SYNPCCP_0234	COG1420	regulation of RNA biosynthetic process
SYNPCCP_0235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SYNPCCP_0236	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SYNPCCP_0238	COG0003	Pfam Anion-transporting ATPase
SYNPCCP_0239	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYNPCCP_0242	COG0484	heat shock protein binding
SYNPCCP_0243	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SYNPCCP_0245	COG0463	Glycosyl transferase, family 2
SYNPCCP_0245	COG1216	Glycosyl transferase, family 2
SYNPCCP_0247	COG0077	Prephenate dehydratase
SYNPCCP_0247	COG1605	Chorismate mutase
SYNPCCP_0248	COG4251	negative regulation of phosphorylation
SYNPCCP_0248	COG3706	GGDEF domain
SYNPCCP_0248	COG5001	Diguanylate cyclase
SYNPCCP_0248	COG2203	Gaf domain
SYNPCCP_0250	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SYNPCCP_0256	COG0589	response to stress
SYNPCCP_0257	COG2226	methyltransferase
SYNPCCP_0259	COG0538	isocitrate dehydrogenase activity
SYNPCCP_0260	COG4636	protein conserved in cyanobacteria
SYNPCCP_0262	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_0265	COG0762	integral membrane protein
SYNPCCP_0266	COG1840	ABC-type Fe3 transport system, periplasmic component
SYNPCCP_0267	COG0336	Belongs to the RNA methyltransferase TrmD family
SYNPCCP_0269	COG0205	6-phosphofructokinase activity
SYNPCCP_0270	COG1289	transmembrane transporter activity
SYNPCCP_0271	COG1555	photosystem II stabilization
SYNPCCP_0273	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SYNPCCP_0274	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SYNPCCP_0275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SYNPCCP_0280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SYNPCCP_0281	COG0277	FAD linked oxidase domain protein
SYNPCCP_0285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SYNPCCP_0287	COG0408	coproporphyrinogen oxidase activity
SYNPCCP_0288	COG5398	heme oxygenase
SYNPCCP_0290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SYNPCCP_0293	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SYNPCCP_0294	COG0672	)-iron permease
SYNPCCP_0295	COG0592	DNA-directed DNA polymerase activity
SYNPCCP_0296	COG0159	tryptophan synthase activity
SYNPCCP_0299	COG0436	Aminotransferase
SYNPCCP_0301	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SYNPCCP_0304	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SYNPCCP_0306	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SYNPCCP_0307	COG0701	Predicted permease
SYNPCCP_0311	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SYNPCCP_0312	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SYNPCCP_0313	COG4636	protein conserved in cyanobacteria
SYNPCCP_0314	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SYNPCCP_0317	COG0489	protein tyrosine kinase activity
SYNPCCP_0317	COG3206	protein involved in exopolysaccharide biosynthesis
SYNPCCP_0325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYNPCCP_0333	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SYNPCCP_0334	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SYNPCCP_0335	COG1088	dTDP-glucose 4,6-dehydratase activity
SYNPCCP_0336	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNPCCP_0339	COG1215	transferase activity, transferring glycosyl groups
SYNPCCP_0341	COG1215	transferase activity, transferring glycosyl groups
SYNPCCP_0342	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_0347	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNPCCP_0352	COG0297	glycogen (starch) synthase activity
SYNPCCP_0353	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_0354	COG1598	PFAM Uncharacterised protein family UPF0150
SYNPCCP_0356	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYNPCCP_0362	COG0110	maltose O-acetyltransferase activity
SYNPCCP_0365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYNPCCP_0367	COG3781	membrane
SYNPCCP_0368	COG0045	succinate-CoA ligase (ADP-forming) activity
SYNPCCP_0369	COG0861	Integral membrane protein TerC family
SYNPCCP_0370	COG2268	Band 7 protein
SYNPCCP_0371	COG0463	Glycosyl transferase, family 2
SYNPCCP_0372	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SYNPCCP_0374	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SYNPCCP_0375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SYNPCCP_0376	COG0004	ammonium transporteR
SYNPCCP_0377	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_0380	COG0737	Belongs to the 5'-nucleotidase family
SYNPCCP_0381	COG0529	Catalyzes the synthesis of activated sulfate
SYNPCCP_0382	COG0811	peptide transport
SYNPCCP_0383	COG0848	biopolymer transport protein
SYNPCCP_0384	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SYNPCCP_0384	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SYNPCCP_0386	COG0530	calcium, potassium:sodium antiporter activity
SYNPCCP_0390	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_0391	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SYNPCCP_0397	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SYNPCCP_0398	COG3706	GGDEF domain
SYNPCCP_0398	COG2203	Gaf domain
SYNPCCP_0398	COG4251	negative regulation of phosphorylation
SYNPCCP_0398	COG5001	Diguanylate cyclase
SYNPCCP_0400	COG0471	metal ion transport
SYNPCCP_0400	COG3273	potassium ion transport
SYNPCCP_0406	COG3854	ATPases associated with a variety of cellular activities
SYNPCCP_0407	COG0352	thiamine-phosphate diphosphorylase activity
SYNPCCP_0408	COG0434	BtpA family
SYNPCCP_0412	COG0564	pseudouridine synthase activity
SYNPCCP_0413	COG2203	Gaf domain
SYNPCCP_0413	COG3706	GGDEF domain
SYNPCCP_0413	COG5001	Diguanylate cyclase
SYNPCCP_0413	COG4251	negative regulation of phosphorylation
SYNPCCP_0415	COG0475	glutathione-regulated potassium exporter activity
SYNPCCP_0421	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SYNPCCP_0422	COG1733	regulation of RNA biosynthetic process
SYNPCCP_0423	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SYNPCCP_0431	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SYNPCCP_0434	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNPCCP_0436	COG1487	ribonuclease activity
SYNPCCP_0439	COG2361	Protein of unknown function DUF86
SYNPCCP_0442	COG0070	glutamate synthase
SYNPCCP_0442	COG0069	glutamate synthase activity
SYNPCCP_0442	COG0067	glutamate synthase
SYNPCCP_0445	COG2133	pyrroloquinoline quinone binding
SYNPCCP_0446	COG1797	cobyrinic acid a,c-diamide synthase activity
SYNPCCP_0447	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SYNPCCP_0448	COG1022	Amp-dependent synthetase and ligase
SYNPCCP_0449	COG0784	Response regulator, receiver
SYNPCCP_0452	COG2203	Gaf domain
SYNPCCP_0452	COG0840	transmembrane signaling receptor activity
SYNPCCP_0453	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SYNPCCP_0454	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SYNPCCP_0455	COG2203	Gaf domain
SYNPCCP_0455	COG3706	GGDEF domain
SYNPCCP_0455	COG4251	negative regulation of phosphorylation
SYNPCCP_0455	COG5001	Diguanylate cyclase
SYNPCCP_0456	COG0419	ATPase involved in DNA repair
SYNPCCP_0457	COG0484	heat shock protein binding
SYNPCCP_0458	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SYNPCCP_0460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SYNPCCP_0464	COG1429	ligase activity, forming nitrogen-metal bonds
SYNPCCP_0467	COG3956	TIGRFAM MazG family protein
SYNPCCP_0469	COG5002	protein histidine kinase activity
SYNPCCP_0474	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYNPCCP_0477	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SYNPCCP_0478	COG1247	-acetyltransferase
SYNPCCP_0479	COG0174	glutamine synthetase
SYNPCCP_0481	COG3706	GGDEF domain
SYNPCCP_0481	COG4251	negative regulation of phosphorylation
SYNPCCP_0481	COG5001	Diguanylate cyclase
SYNPCCP_0481	COG2203	Gaf domain
SYNPCCP_0483	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SYNPCCP_0484	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SYNPCCP_0487	COG2310	stress, protein
SYNPCCP_0488	COG0076	glutamate decarboxylase activity
SYNPCCP_0491	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYNPCCP_0492	COG0829	nickel cation binding
SYNPCCP_0495	COG1045	serine acetyltransferase
SYNPCCP_0498	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SYNPCCP_0501	COG0271	Belongs to the BolA IbaG family
SYNPCCP_0502	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SYNPCCP_0503	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SYNPCCP_0507	COG0804	urea catabolic process
SYNPCCP_0510	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNPCCP_0514	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SYNPCCP_0515	COG1773	rubredoxin
SYNPCCP_0516	COG4447	cellulose binding
SYNPCCP_0521	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SYNPCCP_0523	COG3385	transposase activity
SYNPCCP_0527	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SYNPCCP_0528	COG0784	Response regulator, receiver
SYNPCCP_0529	COG3228	Belongs to the MtfA family
SYNPCCP_0536	COG1121	(ABC) transporter
SYNPCCP_0537	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SYNPCCP_0540	COG1702	phosphate starvation-inducible protein PhoH
SYNPCCP_0543	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNPCCP_0547	COG0484	heat shock protein binding
SYNPCCP_0548	COG0443	Heat shock 70 kDa protein
SYNPCCP_0549	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SYNPCCP_0554	COG3659	wide pore channel activity
SYNPCCP_0556	COG2247	cell wall binding repeat
SYNPCCP_0556	COG0860	N-Acetylmuramoyl-L-alanine amidase
SYNPCCP_0568	COG0768	penicillin binding
SYNPCCP_0570	COG0247	lactate metabolic process
SYNPCCP_0572	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNPCCP_0574	COG0583	DNA-binding transcription factor activity
SYNPCCP_0576	COG0384	phenazine biosynthesis protein PhzF
SYNPCCP_0577	COG2319	Wd-40 repeat
SYNPCCP_0578	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNPCCP_0583	COG0475	glutathione-regulated potassium exporter activity
SYNPCCP_0583	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SYNPCCP_0584	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SYNPCCP_0588	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SYNPCCP_0589	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SYNPCCP_0591	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYNPCCP_0592	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SYNPCCP_0595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SYNPCCP_0596	COG0629	single-stranded DNA binding
SYNPCCP_0599	COG0668	transmembrane transport
SYNPCCP_0601	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_0602	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SYNPCCP_0602	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYNPCCP_0603	COG3937	granule-associated protein
SYNPCCP_0606	COG2226	methyltransferase
SYNPCCP_0608	COG0681	Belongs to the peptidase S26 family
SYNPCCP_0610	COG1271	oxidase subunit
SYNPCCP_0611	COG1294	oxidase, subunit
SYNPCCP_0612	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SYNPCCP_0613	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SYNPCCP_0614	COG0412	Dienelactone hydrolase
SYNPCCP_0624	COG2203	Gaf domain
SYNPCCP_0624	COG0840	transmembrane signaling receptor activity
SYNPCCP_0627	COG0784	Response regulator, receiver
SYNPCCP_0628	COG0557	exoribonuclease II activity
SYNPCCP_0630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNPCCP_0633	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SYNPCCP_0635	COG5002	protein histidine kinase activity
SYNPCCP_0636	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SYNPCCP_0637	COG1309	transcriptional regulator
SYNPCCP_0642	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SYNPCCP_0644	COG2385	sporulation resulting in formation of a cellular spore
SYNPCCP_0646	COG3411	Ferredoxin
SYNPCCP_0647	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYNPCCP_0652	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SYNPCCP_0653	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SYNPCCP_0654	COG0237	dephospho-CoA kinase activity
SYNPCCP_0655	COG0237	dephospho-CoA kinase activity
SYNPCCP_0660	COG0515	serine threonine protein kinase
SYNPCCP_0662	COG2988	succinylglutamate desuccinylase activity
SYNPCCP_0663	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYNPCCP_0665	COG0739	heme binding
SYNPCCP_0666	COG0587	DNA-directed DNA polymerase activity
SYNPCCP_0669	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SYNPCCP_0675	COG1006	Multisubunit Na H antiporter MnhC subunit
SYNPCCP_0690	COG1132	(ABC) transporter
SYNPCCP_0691	COG3063	Type IV pilus biogenesis stability protein PilW
SYNPCCP_0692	COG2217	Heavy metal translocating P-type atpase
SYNPCCP_0693	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SYNPCCP_0694	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_0696	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SYNPCCP_0697	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SYNPCCP_0699	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SYNPCCP_0705	COG0557	exoribonuclease II activity
SYNPCCP_0707	COG2208	phosphoserine phosphatase activity
SYNPCCP_0708	COG0165	Argininosuccinate lyase
SYNPCCP_0709	COG2816	NAD+ diphosphatase activity
SYNPCCP_0712	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SYNPCCP_0713	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SYNPCCP_0714	COG1845	cytochrome c oxidase, subunit III
SYNPCCP_0715	COG3118	belongs to the thioredoxin family
SYNPCCP_0717	COG1116	anion transmembrane transporter activity
SYNPCCP_0718	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYNPCCP_0721	COG0375	protein maturation
SYNPCCP_0722	COG0010	Belongs to the arginase family
SYNPCCP_0724	COG3706	GGDEF domain
SYNPCCP_0725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SYNPCCP_0726	COG0495	leucyl-tRNA aminoacylation
SYNPCCP_0727	COG0786	glutamate:sodium symporter activity
SYNPCCP_0729	COG2205	protein histidine kinase activity
SYNPCCP_0731	COG1132	(ABC) transporter
SYNPCCP_0735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SYNPCCP_0736	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SYNPCCP_0737	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SYNPCCP_0742	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SYNPCCP_0743	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SYNPCCP_0745	COG0254	rRNA binding
SYNPCCP_0746	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SYNPCCP_0747	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SYNPCCP_0748	COG0101	tRNA pseudouridine synthase activity
SYNPCCP_0749	COG0203	ribosomal protein L17
SYNPCCP_0750	COG0202	RNA polymerase activity
SYNPCCP_0751	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SYNPCCP_0752	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SYNPCCP_0753	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SYNPCCP_0754	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SYNPCCP_0755	COG0563	adenylate kinase activity
SYNPCCP_0756	COG0201	protein transport
SYNPCCP_0757	COG0200	Binds to the 23S rRNA
SYNPCCP_0758	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SYNPCCP_0759	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SYNPCCP_0760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SYNPCCP_0761	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SYNPCCP_0762	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SYNPCCP_0763	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SYNPCCP_0764	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SYNPCCP_0765	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SYNPCCP_0766	COG0255	Belongs to the universal ribosomal protein uL29 family
SYNPCCP_0767	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SYNPCCP_0768	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SYNPCCP_0769	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SYNPCCP_0770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SYNPCCP_0771	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SYNPCCP_0772	COG0089	rRNA binding
SYNPCCP_0773	COG0088	Forms part of the polypeptide exit tunnel
SYNPCCP_0774	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SYNPCCP_0775	COG0783	Belongs to the Dps family
SYNPCCP_0779	COG2010	Cytochrome c
SYNPCCP_0781	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SYNPCCP_0782	COG0830	nickel cation binding
SYNPCCP_0784	COG1131	(ABC) transporter
SYNPCCP_0789	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SYNPCCP_0790	COG0085	RNA polymerase activity
SYNPCCP_0791	COG0084	hydrolase, TatD family'
SYNPCCP_0792	COG0268	Binds directly to 16S ribosomal RNA
SYNPCCP_0793	COG5002	protein histidine kinase activity
SYNPCCP_0795	COG0210	DNA helicase
SYNPCCP_0795	COG0210	DNA helicase
SYNPCCP_0796	COG1196	nuclear chromosome segregation
SYNPCCP_0797	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SYNPCCP_0801	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYNPCCP_0801	COG0758	DNA mediated transformation
SYNPCCP_0802	COG0393	Putative heavy-metal-binding
SYNPCCP_0804	COG0450	alkyl hydroperoxide reductase
SYNPCCP_0805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SYNPCCP_0806	COG0559	Belongs to the binding-protein-dependent transport system permease family
SYNPCCP_0808	COG1175	transmembrane transport
SYNPCCP_0810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYNPCCP_0815	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_0815	COG3347	Dehydrogenase
SYNPCCP_0819	COG4251	negative regulation of phosphorylation
SYNPCCP_0819	COG5001	Diguanylate cyclase
SYNPCCP_0819	COG3706	GGDEF domain
SYNPCCP_0819	COG2203	Gaf domain
SYNPCCP_0820	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_0821	COG0784	Response regulator, receiver
SYNPCCP_0823	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SYNPCCP_0824	COG2239	Acts as a magnesium transporter
SYNPCCP_0830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SYNPCCP_0831	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SYNPCCP_0832	COG1799	cell septum assembly
SYNPCCP_0833	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SYNPCCP_0833	COG0662	Cupin 2, conserved barrel domain protein
SYNPCCP_0835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SYNPCCP_0836	COG0459	protein refolding
SYNPCCP_0840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SYNPCCP_0841	COG0222	ribosome binding
SYNPCCP_0842	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SYNPCCP_0843	COG0081	regulation of translation
SYNPCCP_0844	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SYNPCCP_0845	COG0250	Participates in transcription elongation, termination and antitermination
SYNPCCP_0846	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SYNPCCP_0847	COG0335	large ribosomal subunit rRNA binding
SYNPCCP_0853	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYNPCCP_0855	COG3243	poly(R)-hydroxyalkanoic acid synthase
SYNPCCP_0857	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SYNPCCP_0859	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_0860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYNPCCP_0862	COG2885	chlorophyll binding
SYNPCCP_0863	COG2885	chlorophyll binding
SYNPCCP_0865	COG1132	(ABC) transporter
SYNPCCP_0867	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_0869	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_0870	COG0508	dehydrogenase complex catalyzes the overall conversion of
SYNPCCP_0870	COG0022	dehydrogenase e1 component
SYNPCCP_0871	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNPCCP_0872	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNPCCP_0873	COG1929	Belongs to the glycerate kinase type-1 family
SYNPCCP_0874	COG3659	wide pore channel activity
SYNPCCP_0875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SYNPCCP_0876	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SYNPCCP_0877	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SYNPCCP_0883	COG0776	regulation of translation
SYNPCCP_0886	COG0514	ATP-dependent DNA helicase (RecQ)
SYNPCCP_0888	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SYNPCCP_0889	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYNPCCP_0891	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SYNPCCP_0899	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_0900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SYNPCCP_0901	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SYNPCCP_0902	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNPCCP_0905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SYNPCCP_0906	COG0242	peptide deformylase activity
SYNPCCP_0908	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SYNPCCP_0913	COG0243	molybdopterin cofactor binding
SYNPCCP_0914	COG1116	anion transmembrane transporter activity
SYNPCCP_0915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYNPCCP_0915	COG1116	anion transmembrane transporter activity
SYNPCCP_0916	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYNPCCP_0917	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYNPCCP_0920	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SYNPCCP_0921	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SYNPCCP_0923	COG0793	Belongs to the peptidase S41A family
SYNPCCP_0925	COG0275	rRNA processing
SYNPCCP_0927	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SYNPCCP_0932	COG1090	epimerase
SYNPCCP_0934	COG0515	serine threonine protein kinase
SYNPCCP_0936	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SYNPCCP_0937	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SYNPCCP_0938	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SYNPCCP_0939	COG0659	secondary active sulfate transmembrane transporter activity
SYNPCCP_0940	COG0589	response to stress
SYNPCCP_0941	COG1233	COG1233 Phytoene dehydrogenase and related
SYNPCCP_0944	COG1053	succinate dehydrogenase
SYNPCCP_0945	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYNPCCP_0946	COG0537	adenosine 5'-monophosphoramidase activity
SYNPCCP_0952	COG0402	S-adenosylhomocysteine deaminase activity
SYNPCCP_0955	COG2267	carboxylic ester hydrolase activity
SYNPCCP_0957	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SYNPCCP_0958	COG0189	ligase activity
SYNPCCP_0960	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SYNPCCP_0961	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SYNPCCP_0965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SYNPCCP_0966	COG0312	modulator of DNA gyrase
SYNPCCP_0970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SYNPCCP_0972	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SYNPCCP_0972	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SYNPCCP_0975	COG2140	Oxalate decarboxylase
SYNPCCP_0976	COG0058	SHG alpha-glucan phosphorylase activity
SYNPCCP_0980	COG0515	serine threonine protein kinase
SYNPCCP_0983	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SYNPCCP_0983	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SYNPCCP_0984	COG4999	Histidine kinase
SYNPCCP_0984	COG3850	Histidine kinase
SYNPCCP_0984	COG2205	protein histidine kinase activity
SYNPCCP_0984	COG3437	response regulator, receiver
SYNPCCP_0990	COG0546	phosphoglycolate phosphatase activity
SYNPCCP_0991	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SYNPCCP_0992	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SYNPCCP_0994	COG0501	Belongs to the peptidase M48B family
SYNPCCP_0995	COG0539	negative regulation of cytoplasmic translation
SYNPCCP_0997	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SYNPCCP_0998	COG1132	(ABC) transporter
SYNPCCP_0999	COG0469	pyruvate kinase activity
SYNPCCP_1003	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SYNPCCP_1004	COG1268	BioY protein
SYNPCCP_1005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SYNPCCP_1008	COG3659	wide pore channel activity
SYNPCCP_1011	COG0058	SHG alpha-glucan phosphorylase activity
SYNPCCP_1013	COG0575	Belongs to the CDS family
SYNPCCP_1018	COG1970	mechanosensitive ion channel activity
SYNPCCP_1019	COG0632	four-way junction helicase activity
SYNPCCP_1020	COG1836	PFAM Integral membrane protein DUF92
SYNPCCP_1021	COG0446	pyridine nucleotide-disulphide oxidoreductase
SYNPCCP_1022	COG0724	RNA recognition motif
SYNPCCP_1023	COG0154	amidase activity
SYNPCCP_1024	COG0739	heme binding
SYNPCCP_1025	COG0509	glycine decarboxylation via glycine cleavage system
SYNPCCP_1028	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNPCCP_1032	COG1316	TRANSCRIPTIONal
SYNPCCP_1034	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SYNPCCP_1036	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SYNPCCP_1037	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SYNPCCP_1039	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_1042	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNPCCP_1045	COG0322	excinuclease ABC activity
SYNPCCP_1050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SYNPCCP_1052	COG3258	Cytochrome c
SYNPCCP_1053	COG0723	plastoquinol--plastocyanin reductase activity
SYNPCCP_1058	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SYNPCCP_1063	COG2319	Wd-40 repeat
SYNPCCP_1064	COG2319	Wd-40 repeat
SYNPCCP_1068	COG1082	Xylose isomerase domain protein TIM barrel
SYNPCCP_1071	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SYNPCCP_1076	COG1366	Belongs to the anti-sigma-factor antagonist family
SYNPCCP_1079	COG2770	Histidine kinase
SYNPCCP_1079	COG2208	phosphoserine phosphatase activity
SYNPCCP_1085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SYNPCCP_1086	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SYNPCCP_1091	COG1741	Belongs to the pirin family
SYNPCCP_1093	COG1193	negative regulation of DNA recombination
SYNPCCP_1094	COG0631	protein serine/threonine phosphatase activity
SYNPCCP_1095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNPCCP_1096	COG3937	granule-associated protein
SYNPCCP_1100	COG1181	Belongs to the D-alanine--D-alanine ligase family
SYNPCCP_1101	COG3932	Exopolysaccharide synthesis, ExoD
SYNPCCP_1102	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SYNPCCP_1104	COG0360	Binds together with S18 to 16S ribosomal RNA
SYNPCCP_1105	COG0179	Fumarylacetoacetate (FAA) hydrolase
SYNPCCP_1106	COG1413	lyase activity
SYNPCCP_1107	COG0641	radical SAM
SYNPCCP_1114	COG0083	homoserine kinase activity
SYNPCCP_1116	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SYNPCCP_1117	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_1119	COG0196	riboflavin kinase activity
SYNPCCP_1123	COG0180	Tryptophanyl-tRNA synthetase
SYNPCCP_1125	COG1713	HD superfamily hydrolase involved in NAD metabolism
SYNPCCP_1126	COG0799	negative regulation of ribosome biogenesis
SYNPCCP_1128	COG0181	hydroxymethylbilane synthase activity
SYNPCCP_1129	COG0427	acetyl-CoA hydrolase
SYNPCCP_1130	COG0857	belongs to the CobB CobQ family
SYNPCCP_1130	COG0280	phosphate acetyltransferase
SYNPCCP_1132	COG1489	DNA binding
SYNPCCP_1134	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNPCCP_1135	COG0602	queuosine metabolic process
SYNPCCP_1136	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SYNPCCP_1137	COG0612	Peptidase, M16
SYNPCCP_1138	COG0612	Peptidase, M16
SYNPCCP_1140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SYNPCCP_1143	COG1372	Participates in initiation and elongation during chromosome replication
SYNPCCP_1143	COG0187	DNA topoisomerase II activity
SYNPCCP_1146	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SYNPCCP_1146	COG0646	methionine synthase
SYNPCCP_1148	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SYNPCCP_1153	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_1155	COG2197	response regulator
SYNPCCP_1156	COG4251	negative regulation of phosphorylation
SYNPCCP_1156	COG2203	Gaf domain
SYNPCCP_1156	COG5001	Diguanylate cyclase
SYNPCCP_1156	COG3706	GGDEF domain
SYNPCCP_1158	COG0616	signal peptide processing
SYNPCCP_1160	COG0596	Alpha beta hydrolase
SYNPCCP_1161	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SYNPCCP_1163	COG0747	negative chemotaxis
SYNPCCP_1165	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
SYNPCCP_1173	COG4968	Prepilin-type N-terminal cleavage methylation domain
SYNPCCP_1174	COG4968	Prepilin-type N-terminal cleavage methylation domain
SYNPCCP_1179	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNPCCP_1180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNPCCP_1181	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SYNPCCP_1183	COG2199	diguanylate cyclase activity
SYNPCCP_1184	COG0750	zinc metalloprotease
SYNPCCP_1185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SYNPCCP_1187	COG0590	tRNA wobble adenosine to inosine editing
SYNPCCP_1189	COG0415	Belongs to the DNA photolyase family
SYNPCCP_1191	COG3429	Glucose-6-phosphate dehydrogenase subunit
SYNPCCP_1191	COG3409	Peptidoglycan-binding domain 1 protein
SYNPCCP_1193	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SYNPCCP_1194	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SYNPCCP_1196	COG1122	ATPase activity
SYNPCCP_1197	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYNPCCP_1199	COG0678	peroxiredoxin activity
SYNPCCP_1206	COG1252	NADH dehydrogenase
SYNPCCP_1208	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SYNPCCP_1213	COG0415	Belongs to the DNA photolyase family
SYNPCCP_1216	COG1595	DNA-templated transcription, initiation
SYNPCCP_1224	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SYNPCCP_1226	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SYNPCCP_1227	COG3339	Conserved Protein
SYNPCCP_1229	COG0312	modulator of DNA gyrase
SYNPCCP_1230	COG0482	sulfurtransferase activity
SYNPCCP_1233	COG0488	(ABC) transporter
SYNPCCP_1234	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SYNPCCP_1236	COG0284	orotidine-5'-phosphate decarboxylase activity
SYNPCCP_1244	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SYNPCCP_1246	COG0697	spore germination
SYNPCCP_1253	COG0583	DNA-binding transcription factor activity
SYNPCCP_1259	COG2814	Major facilitator Superfamily
SYNPCCP_1260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYNPCCP_1261	COG0573	inorganic phosphate transmembrane transporter activity
SYNPCCP_1262	COG0581	inorganic phosphate transmembrane transporter activity
SYNPCCP_1263	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SYNPCCP_1264	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYNPCCP_1265	COG2154	pterin-4-alpha-carbinolamine dehydratase
SYNPCCP_1270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SYNPCCP_1270	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYNPCCP_1271	COG1562	ergosterol biosynthetic process
SYNPCCP_1272	COG3788	relative of glutathione S-transferase, MAPEG superfamily
SYNPCCP_1273	COG0831	urea catabolic process
SYNPCCP_1274	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SYNPCCP_1278	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SYNPCCP_1279	COG0730	response to heat
SYNPCCP_1281	COG2188	Transcriptional regulator
SYNPCCP_1284	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SYNPCCP_1285	COG0640	Transcriptional regulator
SYNPCCP_1286	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SYNPCCP_1287	COG1754	DNA topoisomerase type I activity
SYNPCCP_1287	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SYNPCCP_1294	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SYNPCCP_1300	COG2264	protein methyltransferase activity
SYNPCCP_1301	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SYNPCCP_1304	COG0386	Belongs to the glutathione peroxidase family
SYNPCCP_1305	COG0183	Belongs to the thiolase family
SYNPCCP_1306	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_1308	COG3850	Histidine kinase
SYNPCCP_1308	COG3437	response regulator, receiver
SYNPCCP_1308	COG2205	protein histidine kinase activity
SYNPCCP_1308	COG4999	Histidine kinase
SYNPCCP_1312	COG4242	Belongs to the peptidase S51 family
SYNPCCP_1313	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SYNPCCP_1313	COG0189	ligase activity
SYNPCCP_1319	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SYNPCCP_1320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SYNPCCP_1322	COG0285	dihydrofolate synthase activity
SYNPCCP_1326	COG4636	protein conserved in cyanobacteria
SYNPCCP_1328	COG1606	tRNA processing
SYNPCCP_1330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SYNPCCP_1331	COG2045	Belongs to the ComB family
SYNPCCP_1332	COG0778	Nitroreductase
SYNPCCP_1333	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SYNPCCP_1335	COG0516	GMP reductase activity
SYNPCCP_1336	COG0395	ABC-type sugar transport system, permease component
SYNPCCP_1337	COG3268	Saccharopine dehydrogenase
SYNPCCP_1340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SYNPCCP_1341	COG1121	(ABC) transporter
SYNPCCP_1342	COG0803	Belongs to the bacterial solute-binding protein 9 family
SYNPCCP_1344	COG4251	negative regulation of phosphorylation
SYNPCCP_1345	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SYNPCCP_1347	COG0583	DNA-binding transcription factor activity
SYNPCCP_1348	COG0025	NhaP-type Na H and K H
SYNPCCP_1349	COG2197	response regulator
SYNPCCP_1350	COG5002	protein histidine kinase activity
SYNPCCP_1351	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SYNPCCP_1352	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SYNPCCP_1354	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SYNPCCP_1355	COG2205	protein histidine kinase activity
SYNPCCP_1357	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYNPCCP_1361	COG2385	sporulation resulting in formation of a cellular spore
SYNPCCP_1362	COG0649	NAD binding
SYNPCCP_1365	COG0429	hydrolase of the alpha beta-hydrolase fold
SYNPCCP_1367	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SYNPCCP_1368	COG3536	Protein conserved in bacteria
SYNPCCP_1369	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SYNPCCP_1370	COG0716	FMN binding
SYNPCCP_1372	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SYNPCCP_1373	COG0012	GTP binding
SYNPCCP_1374	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYNPCCP_1385	COG3842	ATPase activity
SYNPCCP_1387	COG1840	ABC-type Fe3 transport system, periplasmic component
SYNPCCP_1388	COG0222	ribosome binding
SYNPCCP_1390	COG2066	Belongs to the glutaminase family
SYNPCCP_1394	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SYNPCCP_1397	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SYNPCCP_1398	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SYNPCCP_1399	COG1333	cytochrome c biogenesis protein
SYNPCCP_1401	COG1657	PFAM Prenyltransferase squalene oxidase
SYNPCCP_1409	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SYNPCCP_1411	COG1494	fructose-1,6-bisphosphatase
SYNPCCP_1414	COG2346	COG2346, Truncated hemoglobins
SYNPCCP_1415	COG4999	Histidine kinase
SYNPCCP_1415	COG3850	Histidine kinase
SYNPCCP_1415	COG3437	response regulator, receiver
SYNPCCP_1415	COG2205	protein histidine kinase activity
SYNPCCP_1417	COG3437	response regulator, receiver
SYNPCCP_1418	COG1917	Cupin 2, conserved barrel domain protein
SYNPCCP_1419	COG0552	protein localization to endoplasmic reticulum
SYNPCCP_1421	COG5002	protein histidine kinase activity
SYNPCCP_1421	COG0784	Response regulator, receiver
SYNPCCP_1421	COG2205	protein histidine kinase activity
SYNPCCP_1422	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SYNPCCP_1424	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SYNPCCP_1428	COG0667	Aldo Keto reductase
SYNPCCP_1429	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYNPCCP_1431	COG0442	prolyl-tRNA aminoacylation
SYNPCCP_1433	COG4372	Transposase
SYNPCCP_1434	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNPCCP_1438	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_1439	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SYNPCCP_1440	COG0416	fatty acid biosynthetic process
SYNPCCP_1441	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SYNPCCP_1444	COG0347	Belongs to the P(II) protein family
SYNPCCP_1445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SYNPCCP_1450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SYNPCCP_1451	COG0473	3-isopropylmalate dehydrogenase activity
SYNPCCP_1453	COG1575	Belongs to the MenA family. Type 1 subfamily
SYNPCCP_1455	COG0656	L-ascorbic acid biosynthetic process
SYNPCCP_1462	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SYNPCCP_1464	COG2161	toxin-antitoxin pair type II binding
SYNPCCP_1467	COG3385	transposase activity
SYNPCCP_1469	COG3385	transposase activity
SYNPCCP_1471	COG0517	IMP dehydrogenase activity
SYNPCCP_1471	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SYNPCCP_1474	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SYNPCCP_1476	COG1215	transferase activity, transferring glycosyl groups
SYNPCCP_1480	COG1216	Glycosyl transferase, family 2
SYNPCCP_1481	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SYNPCCP_1484	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_1489	COG0463	Glycosyl transferase, family 2
SYNPCCP_1490	COG0113	porphobilinogen synthase activity
SYNPCCP_1492	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SYNPCCP_1493	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SYNPCCP_1497	COG0312	modulator of DNA gyrase
SYNPCCP_1498	COG2890	protein-(glutamine-N5) methyltransferase activity
SYNPCCP_1499	COG2205	protein histidine kinase activity
SYNPCCP_1502	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SYNPCCP_1503	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SYNPCCP_1508	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_1510	COG2205	protein histidine kinase activity
SYNPCCP_1510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYNPCCP_1511	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SYNPCCP_1512	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SYNPCCP_1513	COG0612	Peptidase, M16
SYNPCCP_1514	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SYNPCCP_1515	COG3259	Nickel-dependent hydrogenase
SYNPCCP_1518	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
SYNPCCP_1519	COG1034	ATP synthesis coupled electron transport
SYNPCCP_1526	COG0702	epimerase
SYNPCCP_1533	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SYNPCCP_1534	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SYNPCCP_1537	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SYNPCCP_1539	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SYNPCCP_1540	COG0673	inositol 2-dehydrogenase activity
SYNPCCP_1543	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SYNPCCP_1544	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SYNPCCP_1552	COG0095	Lipoate-protein ligase
SYNPCCP_1555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SYNPCCP_1557	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SYNPCCP_1560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SYNPCCP_1561	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SYNPCCP_1562	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SYNPCCP_1563	COG0457	Tetratricopeptide repeat
SYNPCCP_1564	COG1160	GTP binding
SYNPCCP_1568	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SYNPCCP_1570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SYNPCCP_1571	COG0052	Belongs to the universal ribosomal protein uS2 family
SYNPCCP_1572	COG0387	Pfam Sodium calcium exchanger
SYNPCCP_1573	COG0717	Belongs to the dCTP deaminase family
SYNPCCP_1579	COG3385	transposase activity
SYNPCCP_1580	COG1253	flavin adenine dinucleotide binding
SYNPCCP_1582	COG3046	protein related to deoxyribodipyrimidine photolyase
SYNPCCP_1583	COG0516	GMP reductase activity
SYNPCCP_1583	COG0517	IMP dehydrogenase activity
SYNPCCP_1585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SYNPCCP_1589	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SYNPCCP_1589	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SYNPCCP_1590	COG0288	reversible hydration of carbon dioxide
SYNPCCP_1591	COG1045	serine acetyltransferase
SYNPCCP_1592	COG0166	Belongs to the GPI family
SYNPCCP_1593	COG3239	Fatty acid desaturase
SYNPCCP_1594	COG1672	PFAM Archaeal ATPase
SYNPCCP_1595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SYNPCCP_1596	COG2010	Cytochrome c
SYNPCCP_1597	COG0359	binds to the 23S rRNA
SYNPCCP_1599	COG1032	radical SAM domain protein
SYNPCCP_1604	COG0298	carbon dioxide binding
SYNPCCP_1605	COG0109	protoheme IX farnesyltransferase activity
SYNPCCP_1606	COG1612	heme a metabolic process
SYNPCCP_1610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SYNPCCP_1611	COG5001	Diguanylate cyclase
SYNPCCP_1611	COG1716	ATPase activity
SYNPCCP_1612	COG3631	Ketosteroid isomerase-related protein
SYNPCCP_1614	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SYNPCCP_1614	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SYNPCCP_1616	COG0107	imidazoleglycerol-phosphate synthase activity
SYNPCCP_1621	COG2205	protein histidine kinase activity
SYNPCCP_1621	COG2202	Pas domain
SYNPCCP_1624	COG4783	chaperone-mediated protein folding
SYNPCCP_1625	COG4999	Histidine kinase
SYNPCCP_1625	COG3850	Histidine kinase
SYNPCCP_1625	COG2205	protein histidine kinase activity
SYNPCCP_1625	COG3437	response regulator, receiver
SYNPCCP_1627	COG4956	integral membrane protein (PIN domain superfamily)
SYNPCCP_1630	COG1160	GTP binding
SYNPCCP_1632	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SYNPCCP_1635	COG0432	Pfam Uncharacterised protein family UPF0047
SYNPCCP_1636	COG2197	response regulator
SYNPCCP_1637	COG3842	ATPase activity
SYNPCCP_1639	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SYNPCCP_1640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SYNPCCP_1642	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SYNPCCP_1643	COG5398	heme oxygenase
SYNPCCP_1644	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYNPCCP_1646	COG1316	TRANSCRIPTIONal
SYNPCCP_1648	COG3706	GGDEF domain
SYNPCCP_1648	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_1649	COG2770	Histidine kinase
SYNPCCP_1649	COG2208	phosphoserine phosphatase activity
SYNPCCP_1650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SYNPCCP_1652	COG0539	negative regulation of cytoplasmic translation
SYNPCCP_1653	COG0358	DNA primase activity
SYNPCCP_1655	COG0009	L-threonylcarbamoyladenylate synthase
SYNPCCP_1659	COG0589	response to stress
SYNPCCP_1663	COG2082	Precorrin-8x methylmutase
SYNPCCP_1665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SYNPCCP_1666	COG0594	ribonuclease P activity
SYNPCCP_1668	COG0706	membrane insertase activity
SYNPCCP_1670	COG0484	heat shock protein binding
SYNPCCP_1671	COG0483	inositol monophosphate 1-phosphatase activity
SYNPCCP_1672	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYNPCCP_1673	COG0791	NLP P60 protein
SYNPCCP_1676	COG0540	Belongs to the ATCase OTCase family
SYNPCCP_1678	COG1215	transferase activity, transferring glycosyl groups
SYNPCCP_1680	COG0300	oxidoreductase activity
SYNPCCP_1680	COG3000	fatty acid hydroxylase
SYNPCCP_1681	COG2211	Major facilitator Superfamily
SYNPCCP_1684	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNPCCP_1687	COG0723	plastoquinol--plastocyanin reductase activity
SYNPCCP_1688	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYNPCCP_1689	COG2274	protein secretion by the type I secretion system
SYNPCCP_1690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SYNPCCP_1691	COG2192	nodulation
SYNPCCP_1693	COG0772	Belongs to the SEDS family
SYNPCCP_1694	COG0405	Gamma-glutamyltransferase
SYNPCCP_1697	COG3659	wide pore channel activity
SYNPCCP_1705	COG0037	tRNA processing
SYNPCCP_1706	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SYNPCCP_1707	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_1708	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_1709	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_1717	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYNPCCP_1719	COG0628	permease
SYNPCCP_1722	COG0066	3-isopropylmalate dehydratase activity
SYNPCCP_1723	COG0504	CTP synthase activity
SYNPCCP_1725	COG2204	response regulator
SYNPCCP_1727	COG0259	pyridoxamine-phosphate oxidase activity
SYNPCCP_1730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SYNPCCP_1733	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SYNPCCP_1734	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SYNPCCP_1735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SYNPCCP_1735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SYNPCCP_1736	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SYNPCCP_1738	COG1619	proteins homologs of microcin C7 resistance protein MccF
SYNPCCP_1739	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNPCCP_1742	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SYNPCCP_1744	COG0051	transcription antitermination factor activity, RNA binding
SYNPCCP_1745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SYNPCCP_1746	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SYNPCCP_1747	COG0049	tRNA binding
SYNPCCP_1748	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SYNPCCP_1750	COG0151	Belongs to the GarS family
SYNPCCP_1752	COG0698	ribose 5-phosphate isomerase
SYNPCCP_1758	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SYNPCCP_1759	COG2046	Belongs to the sulfate adenylyltransferase family
SYNPCCP_1760	COG0297	glycogen (starch) synthase activity
SYNPCCP_1763	COG0644	oxidoreductase
SYNPCCP_1764	COG0371	Dehydrogenase
SYNPCCP_1767	COG2119	membrane
SYNPCCP_1768	COG0386	Belongs to the glutathione peroxidase family
SYNPCCP_1770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SYNPCCP_1775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SYNPCCP_1776	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SYNPCCP_1778	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SYNPCCP_1779	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYNPCCP_1781	COG0375	protein maturation
SYNPCCP_1784	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SYNPCCP_1785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SYNPCCP_1786	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SYNPCCP_1787	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SYNPCCP_1788	COG1134	teichoic acid transport
SYNPCCP_1793	COG1012	belongs to the aldehyde dehydrogenase family
SYNPCCP_1796	COG3385	transposase activity
SYNPCCP_1803	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYNPCCP_1805	COG1304	FMN binding
SYNPCCP_1806	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_1808	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SYNPCCP_1810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYNPCCP_1810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SYNPCCP_1811	COG2203	Gaf domain
SYNPCCP_1811	COG4251	negative regulation of phosphorylation
SYNPCCP_1811	COG3706	GGDEF domain
SYNPCCP_1811	COG5001	Diguanylate cyclase
SYNPCCP_1812	COG0784	Response regulator, receiver
SYNPCCP_1814	COG0072	phenylalanine-tRNA ligase activity
SYNPCCP_1814	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SYNPCCP_1815	COG0515	serine threonine protein kinase
SYNPCCP_1815	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNPCCP_1816	COG2197	response regulator
SYNPCCP_1817	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SYNPCCP_1820	COG0157	Belongs to the NadC ModD family
SYNPCCP_1823	COG2082	Precorrin-8x methylmutase
SYNPCCP_1824	COG0612	Peptidase, M16
SYNPCCP_1825	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYNPCCP_1827	COG0656	L-ascorbic acid biosynthetic process
SYNPCCP_1828	COG3588	fructose-bisphosphate aldolase
SYNPCCP_1830	COG0798	PFAM Bile acid sodium symporter
SYNPCCP_1831	COG0431	NADPH-dependent FMN reductase
SYNPCCP_1832	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SYNPCCP_1836	COG0488	(ABC) transporter
SYNPCCP_1838	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SYNPCCP_1842	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SYNPCCP_1843	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SYNPCCP_1844	COG0561	phosphatase activity
SYNPCCP_1846	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SYNPCCP_1847	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYNPCCP_1849	COG0215	cysteine-tRNA ligase activity
SYNPCCP_1850	COG0424	maF-like protein
SYNPCCP_1853	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SYNPCCP_1854	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SYNPCCP_1855	COG0463	Glycosyl transferase, family 2
SYNPCCP_1856	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SYNPCCP_1859	COG1472	Belongs to the glycosyl hydrolase 3 family
SYNPCCP_1860	COG2816	NAD+ diphosphatase activity
SYNPCCP_1861	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SYNPCCP_1862	COG1280	lysine exporter protein (LysE YggA)
SYNPCCP_1865	COG0564	pseudouridine synthase activity
SYNPCCP_1867	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_1874	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SYNPCCP_1877	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_1879	COG0500	methyltransferase
SYNPCCP_1880	COG0542	response to heat
SYNPCCP_1882	COG0572	uridine kinase
SYNPCCP_1883	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SYNPCCP_1884	COG0561	phosphatase activity
SYNPCCP_1887	COG0571	ribonuclease III activity
SYNPCCP_1888	COG0390	transport system, permease component
SYNPCCP_1889	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SYNPCCP_1890	COG2161	toxin-antitoxin pair type II binding
SYNPCCP_1892	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SYNPCCP_1893	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYNPCCP_1893	COG0426	domain, Protein
SYNPCCP_1894	COG0497	DNA recombination
SYNPCCP_1896	COG3751	2OG-Fe(II) oxygenase superfamily
SYNPCCP_1900	COG2161	toxin-antitoxin pair type II binding
SYNPCCP_1904	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SYNPCCP_1905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNPCCP_1907	COG1446	asparaginase
SYNPCCP_1908	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SYNPCCP_1910	COG0832	Belongs to the urease beta subunit family
SYNPCCP_1912	COG2226	methyltransferase
SYNPCCP_1915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SYNPCCP_1917	COG0025	NhaP-type Na H and K H
SYNPCCP_1919	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SYNPCCP_1921	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SYNPCCP_1929	COG3239	Fatty acid desaturase
SYNPCCP_1931	COG1950	PFAM Membrane protein of
SYNPCCP_1934	COG1253	flavin adenine dinucleotide binding
SYNPCCP_1935	COG0228	four-way junction DNA binding
SYNPCCP_1939	COG2010	Cytochrome c
SYNPCCP_1942	COG0802	atpase or kinase
SYNPCCP_1943	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SYNPCCP_1943	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SYNPCCP_1948	COG0126	phosphoglycerate kinase activity
SYNPCCP_1949	COG0583	DNA-binding transcription factor activity
SYNPCCP_1950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SYNPCCP_1957	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SYNPCCP_1959	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SYNPCCP_1960	COG0347	Belongs to the P(II) protein family
SYNPCCP_1963	COG0135	phosphoribosylanthranilate isomerase activity
SYNPCCP_1964	COG0697	spore germination
SYNPCCP_1966	COG0418	dihydroorotase activity
SYNPCCP_1967	COG2226	methyltransferase
SYNPCCP_1970	COG1672	PFAM Archaeal ATPase
SYNPCCP_1970	COG2319	Wd-40 repeat
SYNPCCP_1979	COG2815	serine threonine protein kinase
SYNPCCP_1979	COG0515	serine threonine protein kinase
SYNPCCP_1984	COG0233	cytoplasmic translational termination
SYNPCCP_1985	COG0528	UMP kinase activity
SYNPCCP_1986	COG1598	PFAM Uncharacterised protein family UPF0150
SYNPCCP_1987	COG0542	response to heat
SYNPCCP_1993	COG0740	serine-type endopeptidase activity
SYNPCCP_1994	COG0740	serine-type endopeptidase activity
SYNPCCP_1995	COG0006	proline dipeptidase activity
SYNPCCP_1996	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SYNPCCP_2001	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
SYNPCCP_2003	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SYNPCCP_2004	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SYNPCCP_2010	COG2165	general secretion pathway protein
SYNPCCP_2012	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SYNPCCP_2019	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SYNPCCP_2023	COG0105	UTP biosynthetic process
SYNPCCP_2028	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SYNPCCP_2029	COG2937	Belongs to the GPAT DAPAT family
SYNPCCP_2030	COG0501	Belongs to the peptidase M48B family
SYNPCCP_2034	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SYNPCCP_2036	COG0463	Glycosyl transferase, family 2
SYNPCCP_2038	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SYNPCCP_2041	COG0508	dehydrogenase complex catalyzes the overall conversion of
SYNPCCP_2043	COG2217	Heavy metal translocating P-type atpase
SYNPCCP_2045	COG0217	transcriptional regulatory protein
SYNPCCP_2046	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SYNPCCP_2047	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SYNPCCP_2048	COG0739	heme binding
SYNPCCP_2049	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SYNPCCP_2050	COG0321	lipoyl(octanoyl) transferase activity
SYNPCCP_2052	COG0297	glycogen (starch) synthase activity
SYNPCCP_2055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNPCCP_2056	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SYNPCCP_2057	COG2198	Histidine kinase
SYNPCCP_2057	COG0643	Histidine kinase
SYNPCCP_2064	COG1178	ABC-type Fe3 transport system permease component
SYNPCCP_2065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SYNPCCP_2070	COG2197	response regulator
SYNPCCP_2072	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_2077	COG0237	dephospho-CoA kinase activity
SYNPCCP_2077	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNPCCP_2085	COG0516	GMP reductase activity
SYNPCCP_2085	COG0517	IMP dehydrogenase activity
SYNPCCP_2087	COG1937	Protein conserved in bacteria
SYNPCCP_2089	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SYNPCCP_2093	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SYNPCCP_2094	COG0443	Heat shock 70 kDa protein
SYNPCCP_2095	COG0484	heat shock protein binding
SYNPCCP_2098	COG1587	Uroporphyrinogen-III synthase
SYNPCCP_2099	COG2319	Wd-40 repeat
SYNPCCP_2102	COG3385	transposase activity
SYNPCCP_2105	COG1381	Involved in DNA repair and RecF pathway recombination
SYNPCCP_2108	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SYNPCCP_2112	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SYNPCCP_2113	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SYNPCCP_2114	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SYNPCCP_2115	COG5001	Diguanylate cyclase
SYNPCCP_2117	COG1187	pseudouridine synthase activity
SYNPCCP_2118	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SYNPCCP_2124	COG1012	belongs to the aldehyde dehydrogenase family
SYNPCCP_2125	COG5002	protein histidine kinase activity
SYNPCCP_2126	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SYNPCCP_2127	COG2308	Evidence 4 Homologs of previously reported genes of
SYNPCCP_2133	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SYNPCCP_2135	COG0346	lactoylglutathione lyase activity
SYNPCCP_2136	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_2137	COG0742	ribosomal rna small subunit methyltransferase
SYNPCCP_2138	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_2139	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SYNPCCP_2143	COG1104	cysteine desulfurase activity
SYNPCCP_2144	COG1040	competence protein
SYNPCCP_2145	COG1376	ErfK ybiS ycfS ynhG family protein
SYNPCCP_2148	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYNPCCP_2150	COG3659	wide pore channel activity
SYNPCCP_2151	COG0477	Major facilitator Superfamily
SYNPCCP_2152	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SYNPCCP_2153	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SYNPCCP_2154	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYNPCCP_2155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SYNPCCP_2156	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SYNPCCP_2157	COG2003	Belongs to the UPF0758 family
SYNPCCP_2164	COG1131	(ABC) transporter
SYNPCCP_2166	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SYNPCCP_2168	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SYNPCCP_2170	COG0450	alkyl hydroperoxide reductase
SYNPCCP_2171	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SYNPCCP_2173	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SYNPCCP_2175	COG1231	oxidoreductase activity
SYNPCCP_2176	COG2205	protein histidine kinase activity
SYNPCCP_2178	COG0149	triose-phosphate isomerase activity
SYNPCCP_2179	COG0628	permease
SYNPCCP_2182	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SYNPCCP_2183	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SYNPCCP_2186	COG0571	ribonuclease III activity
SYNPCCP_2187	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SYNPCCP_2192	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SYNPCCP_2196	COG3385	transposase activity
SYNPCCP_2198	COG3385	transposase activity
SYNPCCP_2201	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYNPCCP_2202	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SYNPCCP_2205	COG0601	transmembrane transport
SYNPCCP_2206	COG0124	histidyl-tRNA synthetase
SYNPCCP_2215	COG0542	response to heat
SYNPCCP_2216	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SYNPCCP_2217	COG0191	fructose-bisphosphate aldolase activity
SYNPCCP_2218	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SYNPCCP_2222	COG0793	Belongs to the peptidase S41A family
SYNPCCP_2223	COG1850	ribulose-bisphosphate carboxylase activity
SYNPCCP_2225	COG4451	ribulose bisphosphate carboxylase, small
SYNPCCP_2227	COG1285	pathogenesis
SYNPCCP_2229	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYNPCCP_2230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYNPCCP_2232	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SYNPCCP_2233	COG0114	fumarate hydratase activity
SYNPCCP_2238	COG0436	Aminotransferase
SYNPCCP_2239	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNPCCP_2240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SYNPCCP_2241	COG0616	signal peptide processing
SYNPCCP_2242	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SYNPCCP_2243	COG0519	Catalyzes the synthesis of GMP from XMP
SYNPCCP_2243	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SYNPCCP_2245	COG1968	undecaprenyl-diphosphatase activity
SYNPCCP_2249	COG5322	oxidoreductase activity
SYNPCCP_2250	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYNPCCP_2252	COG0751	glycine-tRNA ligase activity
SYNPCCP_2255	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SYNPCCP_2256	COG5002	protein histidine kinase activity
SYNPCCP_2257	COG0445	tRNA wobble uridine modification
SYNPCCP_2261	COG3794	PFAM blue (type 1) copper domain protein
SYNPCCP_2264	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNPCCP_2265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SYNPCCP_2266	COG0805	protein transport
SYNPCCP_2267	COG2084	Dehydrogenase
SYNPCCP_2269	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SYNPCCP_2271	COG0586	Pfam SNARE associated Golgi protein
SYNPCCP_2272	COG3118	belongs to the thioredoxin family
SYNPCCP_2273	COG3751	2OG-Fe(II) oxygenase superfamily
SYNPCCP_2274	COG0459	protein refolding
SYNPCCP_2275	COG1131	(ABC) transporter
SYNPCCP_2281	COG4399	Belongs to the UPF0754 family
SYNPCCP_2282	COG0824	Thioesterase
SYNPCCP_2283	COG4948	Mandelate Racemase Muconate Lactonizing
SYNPCCP_2284	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYNPCCP_2285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SYNPCCP_2286	COG0511	ligase activity, forming carbon-carbon bonds
SYNPCCP_2290	COG0277	FAD linked oxidase domain protein
SYNPCCP_2295	COG0436	Aminotransferase
SYNPCCP_2296	COG0372	Belongs to the citrate synthase family
SYNPCCP_2297	COG2062	phosphohistidine phosphatase, SixA
SYNPCCP_2298	COG0596	Alpha beta hydrolase
SYNPCCP_2301	COG1234	tRNA 3'-trailer cleavage
SYNPCCP_2304	COG0788	formyltetrahydrofolate deformylase activity
SYNPCCP_2308	COG0625	glutathione transferase activity
SYNPCCP_2310	COG0440	acetolactate synthase activity
SYNPCCP_2312	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SYNPCCP_2313	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SYNPCCP_2315	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYNPCCP_2316	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYNPCCP_2318	COG0628	permease
SYNPCCP_2324	COG0628	permease
SYNPCCP_2325	COG0443	Heat shock 70 kDa protein
SYNPCCP_2326	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SYNPCCP_2327	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SYNPCCP_2328	COG0116	Belongs to the methyltransferase superfamily
SYNPCCP_2330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYNPCCP_2330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYNPCCP_2331	COG0612	Peptidase, M16
SYNPCCP_2332	COG0489	protein tyrosine kinase activity
SYNPCCP_2333	COG0439	Biotin carboxylase
SYNPCCP_2334	COG3224	Antibiotic biosynthesis monooxygenase
SYNPCCP_2335	COG0590	tRNA wobble adenosine to inosine editing
SYNPCCP_2336	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SYNPCCP_2339	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SYNPCCP_2341	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SYNPCCP_2342	COG4251	negative regulation of phosphorylation
SYNPCCP_2343	COG0784	Response regulator, receiver
SYNPCCP_2344	COG0556	nucleotide-excision repair
SYNPCCP_2349	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNPCCP_2350	COG2890	protein-(glutamine-N5) methyltransferase activity
SYNPCCP_2351	COG0525	valine-tRNA ligase activity
SYNPCCP_2352	COG5002	protein histidine kinase activity
SYNPCCP_2354	COG0728	peptidoglycan biosynthetic process
SYNPCCP_2357	COG0318	PFAM AMP-dependent synthetase and ligase
SYNPCCP_2360	COG0460	homoserine dehydrogenase
SYNPCCP_2361	COG2091	lysine biosynthetic process via aminoadipic acid
SYNPCCP_2363	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SYNPCCP_2367	COG0475	glutathione-regulated potassium exporter activity
SYNPCCP_2370	COG4232	protein-disulfide reductase activity
SYNPCCP_2372	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SYNPCCP_2373	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SYNPCCP_2374	COG0581	inorganic phosphate transmembrane transporter activity
SYNPCCP_2377	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYNPCCP_2379	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SYNPCCP_2380	COG1842	Phage shock protein A
SYNPCCP_2382	COG0653	protein targeting
SYNPCCP_2383	COG2119	membrane
SYNPCCP_2385	COG2255	four-way junction helicase activity
SYNPCCP_2386	COG2022	thiamine diphosphate biosynthetic process
SYNPCCP_2386	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYNPCCP_2388	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SYNPCCP_2390	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SYNPCCP_2392	COG0752	glycyl-tRNA synthetase alpha subunit
SYNPCCP_2393	COG0668	transmembrane transport
SYNPCCP_2394	COG5002	protein histidine kinase activity
SYNPCCP_2397	COG2211	Major facilitator Superfamily
SYNPCCP_2400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SYNPCCP_2401	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SYNPCCP_2405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYNPCCP_2406	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SYNPCCP_2408	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SYNPCCP_2410	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_2411	COG0406	alpha-ribazole phosphatase activity
SYNPCCP_2413	COG0589	response to stress
SYNPCCP_2413	COG0475	glutathione-regulated potassium exporter activity
SYNPCCP_2415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SYNPCCP_2417	COG1122	ATPase activity
SYNPCCP_2419	COG0310	cobalt ion transport
SYNPCCP_2425	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_2426	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYNPCCP_2429	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SYNPCCP_2430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SYNPCCP_2432	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SYNPCCP_2434	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SYNPCCP_2436	COG1598	PFAM Uncharacterised protein family UPF0150
SYNPCCP_2438	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SYNPCCP_2440	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SYNPCCP_2441	COG0302	gtp cyclohydrolase
SYNPCCP_2442	COG1058	Belongs to the CinA family
SYNPCCP_2442	COG1546	Belongs to the CinA family
SYNPCCP_2443	COG0792	nuclease activity
SYNPCCP_2445	COG2385	sporulation resulting in formation of a cellular spore
SYNPCCP_2445	COG2247	cell wall binding repeat
SYNPCCP_2446	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SYNPCCP_2448	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SYNPCCP_2453	COG0121	glutamine amidotransferase
SYNPCCP_2454	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNPCCP_2455	COG2048	Heterodisulfide reductase, subunit B
SYNPCCP_2456	COG0762	integral membrane protein
SYNPCCP_2459	COG4178	(ABC) transporter
SYNPCCP_2463	COG0824	Thioesterase
SYNPCCP_2464	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SYNPCCP_2469	COG2205	protein histidine kinase activity
SYNPCCP_2469	COG2202	Pas domain
SYNPCCP_2472	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SYNPCCP_2473	COG1410	methionine synthase
SYNPCCP_2473	COG0646	methionine synthase
SYNPCCP_2477	COG1410	methionine synthase
SYNPCCP_2477	COG0646	methionine synthase
SYNPCCP_2480	COG1309	transcriptional regulator
SYNPCCP_2481	COG0534	Mate efflux family protein
SYNPCCP_2484	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SYNPCCP_2485	COG0303	'Molybdopterin
SYNPCCP_2486	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SYNPCCP_2487	COG0746	molybdenum cofactor guanylyltransferase activity
SYNPCCP_2487	COG0315	cyclic pyranopterin monophosphate synthase activity
SYNPCCP_2489	COG0314	molybdopterin synthase activity
SYNPCCP_2491	COG0606	chelatase, subunit chli
SYNPCCP_2492	COG1032	radical SAM domain protein
SYNPCCP_2500	COG0156	8-amino-7-oxononanoate synthase activity
SYNPCCP_2501	COG0024	Methionine aminopeptidase
SYNPCCP_2503	COG0494	nUDIX hydrolase
SYNPCCP_2504	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SYNPCCP_2505	COG0039	L-malate dehydrogenase activity
SYNPCCP_2508	COG0193	aminoacyl-tRNA hydrolase activity
SYNPCCP_2512	COG3263	regulation of cellular component size
SYNPCCP_2513	COG0024	Methionine aminopeptidase
SYNPCCP_2514	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SYNPCCP_2517	COG4243	Vitamin k epoxide reductase
SYNPCCP_2518	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYNPCCP_2518	COG0426	domain, Protein
SYNPCCP_2519	COG0613	PHP domain protein
SYNPCCP_2520	COG2251	uridine kinase activity
SYNPCCP_2521	COG3063	Type IV pilus biogenesis stability protein PilW
SYNPCCP_2522	COG0023	Translation Initiation Factor
SYNPCCP_2532	COG2124	cytochrome p450
SYNPCCP_2534	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SYNPCCP_2537	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SYNPCCP_2540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYNPCCP_2542	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYNPCCP_2544	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SYNPCCP_2545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SYNPCCP_2546	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SYNPCCP_2547	COG4251	negative regulation of phosphorylation
SYNPCCP_2547	COG5001	Diguanylate cyclase
SYNPCCP_2547	COG3706	GGDEF domain
SYNPCCP_2547	COG2203	Gaf domain
SYNPCCP_2548	COG0659	secondary active sulfate transmembrane transporter activity
SYNPCCP_2549	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SYNPCCP_2552	COG0305	Participates in initiation and elongation during chromosome replication
SYNPCCP_2552	COG1372	Participates in initiation and elongation during chromosome replication
SYNPCCP_2553	COG0714	Associated with various cellular activities
SYNPCCP_2556	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SYNPCCP_2557	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SYNPCCP_2558	COG2226	methyltransferase
SYNPCCP_2559	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNPCCP_2560	COG0154	amidase activity
SYNPCCP_2563	COG4251	negative regulation of phosphorylation
SYNPCCP_2563	COG5001	Diguanylate cyclase
SYNPCCP_2563	COG2203	Gaf domain
SYNPCCP_2563	COG3706	GGDEF domain
SYNPCCP_2566	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYNPCCP_2569	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SYNPCCP_2571	COG1959	2 iron, 2 sulfur cluster binding
SYNPCCP_2572	COG5001	Diguanylate cyclase
SYNPCCP_2572	COG4251	negative regulation of phosphorylation
SYNPCCP_2572	COG3706	GGDEF domain
SYNPCCP_2572	COG2203	Gaf domain
SYNPCCP_2573	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SYNPCCP_2575	COG0357	Ribosomal RNA small subunit methyltransferase G
SYNPCCP_2578	COG0719	Fe-S assembly protein
SYNPCCP_2579	COG0396	ATPase activity
SYNPCCP_2580	COG0719	Fe-S assembly protein
SYNPCCP_2581	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SYNPCCP_2582	COG0003	Pfam Anion-transporting ATPase
SYNPCCP_2585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SYNPCCP_2586	COG0720	synthase
SYNPCCP_2589	COG0328	RNA-DNA hybrid ribonuclease activity
SYNPCCP_2590	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_2591	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNPCCP_2592	COG0513	Belongs to the DEAD box helicase family
SYNPCCP_2593	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SYNPCCP_2594	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SYNPCCP_2595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SYNPCCP_2596	COG0443	Heat shock 70 kDa protein
SYNPCCP_2598	COG2226	methyltransferase
SYNPCCP_2599	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SYNPCCP_2600	COG1012	belongs to the aldehyde dehydrogenase family
SYNPCCP_2601	COG1216	Glycosyl transferase, family 2
SYNPCCP_2602	COG0484	heat shock protein binding
SYNPCCP_2604	COG0659	secondary active sulfate transmembrane transporter activity
SYNPCCP_2606	COG1131	(ABC) transporter
SYNPCCP_2607	COG0131	Imidazoleglycerol-phosphate dehydratase
SYNPCCP_2609	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNPCCP_2610	COG4251	negative regulation of phosphorylation
SYNPCCP_2611	COG2197	response regulator
SYNPCCP_2614	COG0515	serine threonine protein kinase
SYNPCCP_2616	COG1028	Short-chain dehydrogenase reductase Sdr
SYNPCCP_2619	COG0436	Aminotransferase
SYNPCCP_2620	COG0586	Pfam SNARE associated Golgi protein
SYNPCCP_2621	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SYNPCCP_2621	COG3264	Mechanosensitive ion channel
SYNPCCP_2624	COG0848	biopolymer transport protein
SYNPCCP_2625	COG0848	biopolymer transport protein
SYNPCCP_2626	COG0811	peptide transport
SYNPCCP_2627	COG1840	ABC-type Fe3 transport system, periplasmic component
SYNPCCP_2629	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNPCCP_2630	COG2205	protein histidine kinase activity
SYNPCCP_2632	COG0456	acetyltransferase
SYNPCCP_2634	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SYNPCCP_2635	COG0047	phosphoribosylformylglycinamidine synthase activity
SYNPCCP_2640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SYNPCCP_2641	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SYNPCCP_2642	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SYNPCCP_2643	COG0628	permease
SYNPCCP_2646	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNPCCP_2647	COG0837	glucose binding
SYNPCCP_2648	COG1132	(ABC) transporter
SYNPCCP_2652	COG0668	transmembrane transport
SYNPCCP_2653	COG1492	cobalamin metabolic process
SYNPCCP_2657	COG0469	pyruvate kinase activity
SYNPCCP_2658	COG2081	HI0933 family
SYNPCCP_2659	COG3118	belongs to the thioredoxin family
SYNPCCP_2662	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SYNPCCP_2665	COG0457	Tetratricopeptide repeat
SYNPCCP_2665	COG0463	Glycosyl transferase, family 2
SYNPCCP_2667	COG0004	ammonium transporteR
SYNPCCP_2668	COG0800	Aldolase
SYNPCCP_2670	COG1480	7TM receptor with intracellular HD hydrolase
SYNPCCP_2671	COG2304	oxidoreductase activity
SYNPCCP_2673	COG1192	Involved in chromosome partitioning
SYNPCCP_2676	COG1473	amidohydrolase
SYNPCCP_2678	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SYNPCCP_2682	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNPCCP_2683	COG2205	protein histidine kinase activity
SYNPCCP_2683	COG0784	Response regulator, receiver
SYNPCCP_2684	COG1192	Involved in chromosome partitioning
SYNPCCP_2688	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_2692	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SYNPCCP_2694	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SYNPCCP_2696	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SYNPCCP_2697	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SYNPCCP_2698	COG2894	cell division
SYNPCCP_2699	COG0850	regulation of cytokinetic process
SYNPCCP_2700	COG1716	ATPase activity
SYNPCCP_2703	COG0574	Belongs to the PEP-utilizing enzyme family
SYNPCCP_2703	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SYNPCCP_2704	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_2704	COG3706	GGDEF domain
SYNPCCP_2707	COG0398	Pfam SNARE associated Golgi protein
SYNPCCP_2708	COG0737	Belongs to the 5'-nucleotidase family
SYNPCCP_2709	COG0454	-acetyltransferase
SYNPCCP_2712	COG1032	radical SAM domain protein
SYNPCCP_2716	COG4585	Histidine kinase
SYNPCCP_2717	COG2197	response regulator
SYNPCCP_2718	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SYNPCCP_2718	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SYNPCCP_2719	COG2267	carboxylic ester hydrolase activity
SYNPCCP_2720	COG4221	oxidoreductase activity
SYNPCCP_2726	COG0024	Methionine aminopeptidase
SYNPCCP_2728	COG1056	cytidyltransferase-related domain
SYNPCCP_2728	COG1051	belongs to the nudix hydrolase family
SYNPCCP_2731	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SYNPCCP_2732	COG5002	protein histidine kinase activity
SYNPCCP_2737	COG2814	Major facilitator Superfamily
SYNPCCP_2739	COG2217	Heavy metal translocating P-type atpase
SYNPCCP_2740	COG1742	UPF0060 membrane protein
SYNPCCP_2741	COG0640	Transcriptional regulator
SYNPCCP_2742	COG2217	Heavy metal translocating P-type atpase
SYNPCCP_2743	COG5002	protein histidine kinase activity
SYNPCCP_2744	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_2749	COG2144	transferase activity, transferring acyl groups
SYNPCCP_2754	COG2072	flavoprotein involved in K transport
SYNPCCP_2755	COG2197	response regulator
SYNPCCP_2758	COG4251	negative regulation of phosphorylation
SYNPCCP_2758	COG5001	Diguanylate cyclase
SYNPCCP_2758	COG2203	Gaf domain
SYNPCCP_2758	COG3706	GGDEF domain
SYNPCCP_2759	COG0842	Transport permease protein
SYNPCCP_2759	COG1131	(ABC) transporter
SYNPCCP_2759	COG1716	ATPase activity
SYNPCCP_2761	COG0515	serine threonine protein kinase
SYNPCCP_2761	COG4991	sh3 domain protein
SYNPCCP_2761	COG3064	Membrane
SYNPCCP_2763	COG0401	homolog of Blt101
SYNPCCP_2768	COG0789	Transcriptional regulator
SYNPCCP_2779	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SYNPCCP_2780	COG0598	Magnesium transport protein CorA
SYNPCCP_2783	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SYNPCCP_2783	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SYNPCCP_2790	COG0251	oxidation-reduction process
SYNPCCP_2791	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SYNPCCP_2792	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SYNPCCP_2793	COG0392	lysyltransferase activity
SYNPCCP_2797	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SYNPCCP_2799	COG0343	queuine tRNA-ribosyltransferase activity
SYNPCCP_2802	COG2886	Uncharacterised protein family (UPF0175)
SYNPCCP_2803	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SYNPCCP_2804	COG0668	transmembrane transport
SYNPCCP_2805	COG0205	6-phosphofructokinase activity
SYNPCCP_2809	COG1013	pyruvate-flavodoxin oxidoreductase activity
SYNPCCP_2809	COG0674	pyruvate-flavodoxin oxidoreductase activity
SYNPCCP_2809	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SYNPCCP_2809	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SYNPCCP_2811	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYNPCCP_2812	COG0725	ABC transporter, periplasmic molybdate-binding protein
SYNPCCP_2817	COG0438	transferase activity, transferring glycosyl groups
SYNPCCP_2821	COG0840	transmembrane signaling receptor activity
SYNPCCP_2822	COG0840	transmembrane signaling receptor activity
SYNPCCP_2822	COG2203	Gaf domain
SYNPCCP_2825	COG0784	Response regulator, receiver
SYNPCCP_2827	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SYNPCCP_2828	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SYNPCCP_2829	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SYNPCCP_2830	COG1803	Methylglyoxal synthase
SYNPCCP_2830	COG1597	lipid kinase activity
SYNPCCP_2836	COG0857	belongs to the CobB CobQ family
SYNPCCP_2837	COG0583	DNA-binding transcription factor activity
SYNPCCP_2838	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYNPCCP_2839	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYNPCCP_2840	COG3659	wide pore channel activity
SYNPCCP_2841	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYNPCCP_2841	COG1116	anion transmembrane transporter activity
SYNPCCP_2842	COG1116	anion transmembrane transporter activity
SYNPCCP_2844	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYNPCCP_2846	COG0724	RNA recognition motif
SYNPCCP_2847	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNPCCP_2848	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SYNPCCP_2849	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SYNPCCP_2850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SYNPCCP_2851	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SYNPCCP_2852	COG1653	transport
SYNPCCP_2853	COG1175	transmembrane transport
SYNPCCP_2854	COG0395	ABC-type sugar transport system, permease component
SYNPCCP_2856	COG2205	protein histidine kinase activity
SYNPCCP_2857	COG0741	lytic transglycosylase activity
SYNPCCP_2859	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SYNPCCP_2862	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SYNPCCP_2863	COG0598	Magnesium transport protein CorA
SYNPCCP_2864	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SYNPCCP_2865	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SYNPCCP_2866	COG0019	diaminopimelate decarboxylase activity
SYNPCCP_2867	COG1160	GTP binding
SYNPCCP_2868	COG0018	arginyl-trna synthetase
SYNPCCP_2869	COG0463	Glycosyl transferase, family 2
SYNPCCP_2871	COG0740	serine-type endopeptidase activity
SYNPCCP_2872	COG0133	tryptophan synthase activity
SYNPCCP_2874	COG1136	(ABC) transporter
SYNPCCP_2875	COG2314	TM2 domain
SYNPCCP_2879	COG0017	Asparaginyl-tRNA synthetase
SYNPCCP_2881	COG0569	domain protein
SYNPCCP_2882	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SYNPCCP_2883	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SYNPCCP_2884	COG0629	single-stranded DNA binding
SYNPCCP_2885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYNPCCP_2887	COG1192	Involved in chromosome partitioning
SYNPCCP_2889	COG2119	membrane
SYNPCCP_2890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SYNPCCP_2891	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SYNPCCP_2893	COG1162	GTPase activity
SYNPCCP_2895	COG0484	heat shock protein binding
SYNPCCP_2896	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SYNPCCP_2897	COG1218	3'(2'),5'-bisphosphate nucleotidase
SYNPCCP_2898	COG0134	indole-3-glycerol-phosphate synthase activity
SYNPCCP_2899	COG0004	ammonium transporteR
SYNPCCP_2900	COG0569	domain protein
SYNPCCP_2901	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SYNPCCP_2902	COG0740	serine-type endopeptidase activity
SYNPCCP_2903	COG0544	peptidyl-prolyl cis-trans isomerase activity
SYNPCCP_2904	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SYNPCCP_2905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SYNPCCP_2906	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SYNPCCP_2908	COG0237	dephospho-CoA kinase activity
SYNPCCP_2911	COG0517	IMP dehydrogenase activity
SYNPCCP_2911	COG1994	Peptidase M50
SYNPCCP_2912	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SYNPCCP_2916	COG0525	valine-tRNA ligase activity
SYNPCCP_2917	COG0713	ATP synthesis coupled electron transport
SYNPCCP_2918	COG0839	Belongs to the complex I subunit 6 family
SYNPCCP_2919	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNPCCP_2920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SYNPCCP_2921	COG0167	dihydroorotate dehydrogenase activity
SYNPCCP_2922	COG2166	iron-sulfur cluster assembly
SYNPCCP_2923	COG1070	Carbohydrate kinase
SYNPCCP_2926	COG0308	aminopeptidase N
SYNPCCP_2927	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SYNPCCP_2928	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SYNPCCP_2929	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SYNPCCP_2931	COG2193	ferroxidase activity
SYNPCCP_2933	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SYNPCCP_2935	COG1834	amidinotransferase
SYNPCCP_2936	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SYNPCCP_2941	COG0745	RESPONSE REGULATOR receiver
SYNPCCP_2942	COG0483	inositol monophosphate 1-phosphatase activity
SYNPCCP_2945	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SYNPCCP_2946	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SYNPCCP_2947	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SYNPCCP_2948	COG4208	sulfate ABC transporter
SYNPCCP_2949	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYNPCCP_2950	COG2165	general secretion pathway protein
SYNPCCP_2953	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SYNPCCP_2956	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SYNPCCP_2957	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SYNPCCP_2958	COG0731	radical SAM domain protein
SYNPCCP_2959	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SYNPCCP_2960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SYNPCCP_2962	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SYNPCCP_2963	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SYNPCCP_2966	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNPCCP_2972	COG0339	signal peptide processing
SYNPCCP_2973	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SYNPCCP_2977	COG1166	arginine decarboxylase activity
SYNPCCP_2979	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SYNPCCP_2983	COG1049	propionate catabolic process, 2-methylcitrate cycle
SYNPCCP_2987	COG0069	glutamate synthase activity
SYNPCCP_2987	COG0070	glutamate synthase
SYNPCCP_2987	COG0067	glutamate synthase
SYNPCCP_2988	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SYNPCCP_2989	COG0505	Belongs to the CarA family
SYNPCCP_2991	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYNPCCP_2992	COG0579	oxidoreductase
SYNPCCP_2993	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SYNPCCP_2994	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SYNPCCP_2995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SYNPCCP_2997	COG1191	sigma factor activity
SYNPCCP_2998	COG0316	Belongs to the HesB IscA family
SYNPCCP_2999	COG0463	Glycosyl transferase, family 2
SYNPCCP_3000	COG2319	Wd-40 repeat
SYNPCCP_3003	COG1691	(AIR) carboxylase
SYNPCCP_3004	COG0739	heme binding
SYNPCCP_3009	COG2052	Domain of unknown function (DUF370)
SYNPCCP_3010	COG3264	Mechanosensitive ion channel
SYNPCCP_3010	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SYNPCCP_3017	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SYNPCCP_3020	COG0363	glucosamine-6-phosphate deaminase activity
SYNPCCP_3024	COG5001	Diguanylate cyclase
SYNPCCP_3024	COG2203	Gaf domain
SYNPCCP_3024	COG3706	GGDEF domain
SYNPCCP_3024	COG4251	negative regulation of phosphorylation
SYNPCCP_3026	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNPCCP_3030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SYNPCCP_3031	COG5001	Diguanylate cyclase
SYNPCCP_3031	COG3300	MHYT domain
SYNPCCP_3033	COG3842	ATPase activity
SYNPCCP_3035	COG1543	Belongs to the glycosyl hydrolase 57 family
SYNPCCP_3037	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SYNPCCP_3038	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYNPCCP_3040	COG0457	Tetratricopeptide repeat
SYNPCCP_3041	COG0148	phosphopyruvate hydratase activity
SYNPCCP_3043	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SYNPCCP_3046	COG0825	malonyl-CoA metabolic process
SYNPCCP_3049	COG1598	PFAM Uncharacterised protein family UPF0150
SYNPCCP_3053	COG4251	negative regulation of phosphorylation
SYNPCCP_3054	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SYNPCCP_3058	COG2994	toxin metabolic process
SYNPCCP_3061	COG0170	dolichyl monophosphate biosynthetic process
SYNPCCP_3062	COG1473	amidohydrolase
SYNPCCP_3063	COG3659	wide pore channel activity
SYNPCCP_3067	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SYNPCCP_3068	COG2203	Gaf domain
SYNPCCP_3068	COG3706	GGDEF domain
SYNPCCP_3068	COG4251	negative regulation of phosphorylation
SYNPCCP_3068	COG5001	Diguanylate cyclase
SYNPCCP_3072	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SYNPCCP_3077	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SYNPCCP_3080	COG2197	response regulator
SYNPCCP_3086	COG2153	protein acetylation
SYNPCCP_3096	COG4581	dead DEAH box helicase
SYNPCCP_3098	COG0322	excinuclease ABC activity
SYNPCCP_3099	COG0129	dihydroxy-acid dehydratase activity
SYNPCCP_3100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SYNPCCP_3106	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SYNPCCP_3107	COG0546	phosphoglycolate phosphatase activity
SYNPCCP_3113	COG0326	Molecular chaperone. Has ATPase activity
SYNPCCP_3114	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNPCCP_3117	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SYNPCCP_3118	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SYNPCCP_3120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SYNPCCP_3125	COG0723	plastoquinol--plastocyanin reductase activity
SYNPCCP_3128	COG1842	Phage shock protein A
SYNPCCP_3132	COG1064	alcohol dehydrogenase
SYNPCCP_3133	COG0137	argininosuccinate synthase activity
SYNPCCP_3136	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SYNPCCP_3141	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYNPCCP_3144	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SYNPCCP_3145	COG0549	Belongs to the carbamate kinase family
SYNPCCP_3148	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNPCCP_3149	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SYNPCCP_3150	COG1136	(ABC) transporter
SYNPCCP_3150	COG0577	efflux transmembrane transporter activity
SYNPCCP_3151	COG0735	belongs to the Fur family
SYNPCCP_3153	COG0138	bifunctional purine biosynthesis protein purh
SYNPCCP_3157	COG0515	serine threonine protein kinase
SYNPCCP_3162	COG0587	DNA-directed DNA polymerase activity
SYNPCCP_3163	COG0481	GTPase activity
SYNPCCP_3164	COG0435	Glutathione S-transferase
SYNPCCP_3167	COG0140	phosphoribosyl-ATP diphosphatase activity
SYNPCCP_3167	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SYNPCCP_3168	COG0523	cobalamin synthesis protein