locus-tag	class	description
KAR29_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAR29_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAR29_00020	COG0445	tRNA wobble uridine modification
KAR29_00035	COG2358	TRAP transporter, solute receptor (TAXI family
KAR29_00065	COG2033	superoxide reductase activity
KAR29_00080	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KAR29_00095	COG0440	acetolactate synthase activity
KAR29_00100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAR29_00105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAR29_00110	COG0028	Belongs to the TPP enzyme family
KAR29_00120	COG0840	transmembrane signaling receptor activity
KAR29_00125	COG2827	Endonuclease containing a URI domain
KAR29_00130	COG0531	amino acid
KAR29_00140	COG0583	DNA-binding transcription factor activity
KAR29_00150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAR29_00170	COG1979	alcohol dehydrogenase
KAR29_00180	COG1473	amidohydrolase
KAR29_00185	COG0840	transmembrane signaling receptor activity
KAR29_00190	COG2801	Transposase and inactivated derivatives
KAR29_00195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAR29_00230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAR29_00235	COG1116	anion transmembrane transporter activity
KAR29_00270	COG2116	formate transmembrane transporter activity
KAR29_00275	COG0746	molybdenum cofactor guanylyltransferase activity
KAR29_00310	COG0561	phosphatase activity
KAR29_00330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KAR29_00340	COG1606	tRNA processing
KAR29_00350	COG1012	belongs to the aldehyde dehydrogenase family
KAR29_00355	COG1525	nuclease
KAR29_00370	COG0357	Ribosomal RNA small subunit methyltransferase G
KAR29_00375	COG1192	Involved in chromosome partitioning
KAR29_00380	COG1475	DNA binding
KAR29_00395	COG1739	Uncharacterized protein family UPF0029
KAR29_00400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KAR29_00410	COG2801	Transposase and inactivated derivatives
KAR29_00420	COG0189	ligase activity
KAR29_00425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAR29_00430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAR29_00435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAR29_00440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_00445	COG1136	(ABC) transporter
KAR29_00445	COG0577	efflux transmembrane transporter activity
KAR29_00450	COG1136	(ABC) transporter
KAR29_00450	COG0577	efflux transmembrane transporter activity
KAR29_00465	COG0745	RESPONSE REGULATOR receiver
KAR29_00470	COG2205	protein histidine kinase activity
KAR29_00485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAR29_00500	COG2204	response regulator
KAR29_00505	COG5002	protein histidine kinase activity
KAR29_00510	COG2205	protein histidine kinase activity
KAR29_00515	COG0745	RESPONSE REGULATOR receiver
KAR29_00540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAR29_00565	COG1132	(ABC) transporter
KAR29_00570	COG1309	transcriptional regulator
KAR29_00580	COG0640	Transcriptional regulator
KAR29_00585	COG0840	transmembrane signaling receptor activity
KAR29_00610	COG0840	transmembrane signaling receptor activity
KAR29_00620	COG1619	proteins homologs of microcin C7 resistance protein MccF
KAR29_00630	COG0444	Belongs to the ABC transporter superfamily
KAR29_00635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_00640	COG0601	transmembrane transport
KAR29_00645	COG0747	negative chemotaxis
KAR29_00655	COG0673	inositol 2-dehydrogenase activity
KAR29_00660	COG3681	Belongs to the UPF0597 family
KAR29_00675	COG3437	response regulator, receiver
KAR29_00680	COG0840	transmembrane signaling receptor activity
KAR29_00695	COG3447	MASE1 domain protein
KAR29_00695	COG5001	Diguanylate cyclase
KAR29_00695	COG5002	protein histidine kinase activity
KAR29_00700	COG2208	phosphoserine phosphatase activity
KAR29_00705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAR29_00715	COG1366	Belongs to the anti-sigma-factor antagonist family
KAR29_00720	COG1472	Belongs to the glycosyl hydrolase 3 family
KAR29_00760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KAR29_00770	COG0704	Plays a role in the regulation of phosphate uptake
KAR29_00780	COG0840	transmembrane signaling receptor activity
KAR29_00785	COG3039	Transposase
KAR29_00805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAR29_00815	COG1129	ABC transporter
KAR29_00820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_00825	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAR29_00830	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAR29_00835	COG1609	Transcriptional regulator
KAR29_00840	COG1744	ABC transporter substrate-binding protein PnrA-like
KAR29_00845	COG3845	ABC transporter
KAR29_00850	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAR29_00855	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAR29_00865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_00875	COG1473	amidohydrolase
KAR29_00885	COG1124	(ABC) transporter
KAR29_00890	COG0444	Belongs to the ABC transporter superfamily
KAR29_00895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_00900	COG0601	transmembrane transport
KAR29_00905	COG0747	negative chemotaxis
KAR29_00920	COG4166	transmembrane transport
KAR29_00925	COG0601	transmembrane transport
KAR29_00930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_00935	COG0444	Belongs to the ABC transporter superfamily
KAR29_00940	COG4608	Belongs to the ABC transporter superfamily
KAR29_00955	COG4948	Mandelate Racemase Muconate Lactonizing
KAR29_00960	COG0583	DNA-binding transcription factor activity
KAR29_00965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAR29_01040	COG2207	Transcriptional regulator
KAR29_01040	COG1917	Cupin 2, conserved barrel domain protein
KAR29_01055	COG1132	(ABC) transporter
KAR29_01060	COG1132	(ABC) transporter
KAR29_01075	COG0784	Response regulator, receiver
KAR29_01075	COG3437	response regulator, receiver
KAR29_01080	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
KAR29_01095	COG1918	ferrous iron import across plasma membrane
KAR29_01095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAR29_01120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAR29_01125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAR29_01130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KAR29_01140	COG2801	Transposase and inactivated derivatives
KAR29_01150	COG0456	acetyltransferase
KAR29_01150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KAR29_01155	COG1074	ATP-dependent DNA helicase activity
KAR29_01190	COG2414	aldehyde ferredoxin oxidoreductase
KAR29_01195	COG0277	FAD linked oxidase domain protein
KAR29_01200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KAR29_01205	COG2086	electron transfer activity
KAR29_01210	COG3875	lactate racemase activity
KAR29_01215	COG2186	Transcriptional regulator
KAR29_01230	COG1518	maintenance of DNA repeat elements
KAR29_01245	COG1857	crispr-associated protein
KAR29_01260	COG1203	CRISPR-associated helicase, Cas3
KAR29_01270	COG0402	S-adenosylhomocysteine deaminase activity
KAR29_01275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAR29_01275	COG0493	'glutamate synthase
KAR29_01280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_01285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAR29_01300	COG0003	Pfam Anion-transporting ATPase
KAR29_01310	COG2252	PERMEase
KAR29_01325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KAR29_01335	COG2235	arginine
KAR29_01340	COG4187	Peptidase family M20/M25/M40
KAR29_01345	COG1115	amino acid carrier protein
KAR29_01355	COG1522	sequence-specific DNA binding
KAR29_01360	COG4106	trans-aconitate 2-methyltransferase activity
KAR29_01370	COG0534	Mate efflux family protein
KAR29_01375	COG1301	dicarboxylic acid transport
KAR29_01380	COG3706	GGDEF domain
KAR29_01405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAR29_01415	COG4608	Belongs to the ABC transporter superfamily
KAR29_01420	COG0444	Belongs to the ABC transporter superfamily
KAR29_01425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_01430	COG0601	transmembrane transport
KAR29_01495	COG1464	Belongs to the NlpA lipoprotein family
KAR29_01500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAR29_01505	COG2011	ABC-type metal ion transport system permease component
KAR29_01515	COG2271	Major facilitator Superfamily
KAR29_01530	COG2414	aldehyde ferredoxin oxidoreductase
KAR29_01535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAR29_01550	COG4608	Belongs to the ABC transporter superfamily
KAR29_01555	COG0444	Belongs to the ABC transporter superfamily
KAR29_01560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_01565	COG0601	transmembrane transport
KAR29_01570	COG4166	transmembrane transport
KAR29_01575	COG0006	proline dipeptidase activity
KAR29_01580	COG1615	UPF0182 protein
KAR29_01600	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KAR29_01610	COG1047	Peptidyl-prolyl cis-trans
KAR29_01615	COG1164	Oligoendopeptidase f
KAR29_01630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAR29_01635	COG1473	amidohydrolase
KAR29_01645	COG3404	Formiminotransferase-cyclodeaminase
KAR29_01650	COG1228	amidohydrolase
KAR29_01670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KAR29_01670	COG3608	succinylglutamate desuccinylase aspartoacylase
KAR29_01685	COG3842	ATPase activity
KAR29_01690	COG4149	molybdate abc transporter
KAR29_01730	COG0535	radical SAM domain protein
KAR29_01765	COG0405	Gamma-glutamyltransferase
KAR29_01795	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KAR29_01800	COG0460	homoserine dehydrogenase
KAR29_01805	COG0840	transmembrane signaling receptor activity
KAR29_01815	COG3426	butyrate kinase activity
KAR29_01820	COG0280	phosphate acetyltransferase
KAR29_01825	COG0280	phosphate acetyltransferase
KAR29_01830	COG3426	butyrate kinase activity
KAR29_01840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAR29_01845	COG1045	serine acetyltransferase
KAR29_01855	COG2217	Heavy metal translocating P-type atpase
KAR29_01865	COG0187	DNA topoisomerase II activity
KAR29_01875	COG0840	transmembrane signaling receptor activity
KAR29_01910	COG0840	transmembrane signaling receptor activity
KAR29_01920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_01920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_01925	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KAR29_01935	COG2814	Major facilitator Superfamily
KAR29_01945	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAR29_01950	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAR29_01970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_01975	COG0601	transmembrane transport
KAR29_01980	COG4166	transmembrane transport
KAR29_01985	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAR29_01990	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAR29_01995	COG1489	DNA binding
KAR29_02015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KAR29_02020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAR29_02035	COG0747	negative chemotaxis
KAR29_02045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_02050	COG0444	Belongs to the ABC transporter superfamily
KAR29_02075	COG2814	Major facilitator Superfamily
KAR29_02080	COG0617	tRNA 3'-terminal CCA addition
KAR29_02090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAR29_02095	COG0577	efflux transmembrane transporter activity
KAR29_02095	COG1136	(ABC) transporter
KAR29_02100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAR29_02105	COG1760	l-serine dehydratase
KAR29_02110	COG1760	l-serine dehydratase
KAR29_02120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KAR29_02125	COG0688	phosphatidylethanolamine metabolic process
KAR29_02130	COG1183	phosphatidylcholine synthase activity
KAR29_02135	COG3859	Proton-coupled thiamine transporter YuaJ
KAR29_02140	COG0426	domain, Protein
KAR29_02150	COG2801	Transposase and inactivated derivatives
KAR29_02155	COG2801	Transposase and inactivated derivatives
KAR29_02160	COG2801	Transposase and inactivated derivatives
KAR29_02165	COG0513	Belongs to the DEAD box helicase family
KAR29_02175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_02175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_02180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_02180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_02185	COG0346	lactoylglutathione lyase activity
KAR29_02190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAR29_02205	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KAR29_02220	COG0281	malic enzyme
KAR29_02245	COG0038	chloride channel
KAR29_02255	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAR29_02260	COG0442	prolyl-tRNA aminoacylation
KAR29_02300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KAR29_02310	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KAR29_02315	COG0450	alkyl hydroperoxide reductase
KAR29_02325	COG1773	rubredoxin
KAR29_02325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KAR29_02360	COG0515	serine threonine protein kinase
KAR29_02365	COG2200	EAL domain
KAR29_02365	COG2771	luxR family
KAR29_02405	COG0583	DNA-binding transcription factor activity
KAR29_02410	COG0739	heme binding
KAR29_02410	COG0741	lytic transglycosylase activity
KAR29_02410	COG1196	nuclear chromosome segregation
KAR29_02415	COG0442	prolyl-tRNA aminoacylation
KAR29_02425	COG0252	asparaginase activity
KAR29_02435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAR29_02440	COG0835	chemotaxis
KAR29_02440	COG0784	Response regulator, receiver
KAR29_02465	COG0419	ATPase involved in DNA repair
KAR29_02465	COG0419	ATPase involved in DNA repair
KAR29_02480	COG2197	response regulator
KAR29_02485	COG4585	Histidine kinase
KAR29_02490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KAR29_02500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAR29_02505	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_02520	COG1560	Kdo2-lipid A biosynthetic process
KAR29_02535	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KAR29_02540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAR29_02545	COG2376	Dihydroxyacetone kinase
KAR29_02550	COG1461	Dihydroxyacetone kinase
KAR29_02560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAR29_02570	COG0493	'glutamate synthase
KAR29_02585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAR29_02590	COG2801	Transposase and inactivated derivatives
KAR29_02615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAR29_02625	COG0835	chemotaxis
KAR29_02640	COG0312	modulator of DNA gyrase
KAR29_02655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAR29_02660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAR29_02675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAR29_02680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KAR29_02690	COG3290	protein histidine kinase activity
KAR29_02695	COG4565	transcriptional regulatory protein
KAR29_02720	COG1566	PFAM secretion protein HlyD family protein
KAR29_02750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KAR29_02810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KAR29_02820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAR29_02825	COG0250	Participates in transcription elongation, termination and antitermination
KAR29_02835	COG0081	regulation of translation
KAR29_02840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAR29_02845	COG0222	ribosome binding
KAR29_02850	COG1515	deoxyribonuclease V activity
KAR29_02860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAR29_02900	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
KAR29_02905	COG1924	4 iron, 4 sulfur cluster binding
KAR29_02910	COG2801	Transposase and inactivated derivatives
KAR29_02915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAR29_02920	COG4496	protein, YerC YecD
KAR29_02930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAR29_02935	COG1067	ATP-dependent peptidase activity
KAR29_02940	COG0482	sulfurtransferase activity
KAR29_02945	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KAR29_02965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAR29_02985	COG1774	PSP1 C-terminal conserved region
KAR29_03000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAR29_03010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAR29_03015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAR29_03035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KAR29_03035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KAR29_03055	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAR29_03060	COG0284	orotidine-5'-phosphate decarboxylase activity
KAR29_03065	COG0167	dihydroorotate dehydrogenase activity
KAR29_03070	COG0543	2 iron, 2 sulfur cluster binding
KAR29_03075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAR29_03080	COG0540	Belongs to the ATCase OTCase family
KAR29_03085	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KAR29_03090	COG0571	ribonuclease III activity
KAR29_03095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAR29_03100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAR29_03110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KAR29_03120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAR29_03125	COG0416	fatty acid biosynthetic process
KAR29_03135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KAR29_03145	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAR29_03150	COG1323	Belongs to the UPF0348 family
KAR29_03155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAR29_03160	COG0742	ribosomal rna small subunit methyltransferase
KAR29_03170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KAR29_03180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAR29_03190	COG1160	GTP binding
KAR29_03195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAR29_03200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAR29_03210	COG0194	GDP metabolic process
KAR29_03215	COG2052	Domain of unknown function (DUF370)
KAR29_03220	COG1561	YicC-like family, N-terminal region
KAR29_03225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAR29_03235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAR29_03240	COG1639	'signal transduction protein
KAR29_03245	COG1187	pseudouridine synthase activity
KAR29_03250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAR29_03255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KAR29_03260	COG0180	Tryptophanyl-tRNA synthetase
KAR29_03275	COG1141	Ferredoxin
KAR29_03280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAR29_03285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAR29_03300	COG1921	L-seryl-tRNASec selenium transferase activity
KAR29_03305	COG1335	isochorismatase
KAR29_03320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAR29_03325	COG0481	GTPase activity
KAR29_03330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KAR29_03335	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAR29_03340	COG0047	phosphoribosylformylglycinamidine synthase activity
KAR29_03345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAR29_03350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAR29_03355	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KAR29_03360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAR29_03365	COG0138	bifunctional purine biosynthesis protein purh
KAR29_03370	COG0151	Belongs to the GarS family
KAR29_03380	COG1242	4 iron, 4 sulfur cluster binding
KAR29_03405	COG0683	leucine binding
KAR29_03415	COG1217	gtp-binding protein TYPA
KAR29_03420	COG4822	anaerobic cobalamin biosynthetic process
KAR29_03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAR29_03430	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KAR29_03445	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KAR29_03485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAR29_03490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAR29_03490	COG1648	precorrin-2 dehydrogenase activity
KAR29_03495	COG0181	hydroxymethylbilane synthase activity
KAR29_03500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAR29_03500	COG1648	precorrin-2 dehydrogenase activity
KAR29_03505	COG1492	cobalamin metabolic process
KAR29_03510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAR29_03515	COG0113	porphobilinogen synthase activity
KAR29_03560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAR29_03565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KAR29_03570	COG1797	cobyrinic acid a,c-diamide synthase activity
KAR29_03575	COG1704	LemA family
KAR29_03580	COG2414	aldehyde ferredoxin oxidoreductase
KAR29_03585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAR29_03610	COG0137	argininosuccinate synthase activity
KAR29_03615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAR29_03620	COG1994	Peptidase M50
KAR29_03625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAR29_03625	COG3620	sequence-specific DNA binding
KAR29_03625	COG0617	tRNA 3'-terminal CCA addition
KAR29_03630	COG0237	dephospho-CoA kinase activity
KAR29_03635	COG0210	DNA helicase
KAR29_03640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAR29_03650	COG0549	Belongs to the carbamate kinase family
KAR29_03655	COG0233	cytoplasmic translational termination
KAR29_03660	COG0528	UMP kinase activity
KAR29_03665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAR29_03670	COG0052	Belongs to the universal ribosomal protein uS2 family
KAR29_03675	COG1937	Protein conserved in bacteria
KAR29_03705	COG0590	tRNA wobble adenosine to inosine editing
KAR29_03710	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KAR29_03715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAR29_03720	COG0778	Nitroreductase
KAR29_03725	COG0488	(ABC) transporter
KAR29_03730	COG3924	membrane
KAR29_03735	COG4145	pantothenate transmembrane transporter activity
KAR29_03740	COG1079	Belongs to the binding-protein-dependent transport system permease family
KAR29_03750	COG3845	ABC transporter
KAR29_03760	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KAR29_03775	COG0733	neurotransmitter:sodium symporter activity
KAR29_03800	COG4942	peptidase
KAR29_03820	COG1162	GTPase activity
KAR29_03830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAR29_03840	COG3039	Transposase
KAR29_03845	COG0667	Aldo Keto reductase
KAR29_03855	COG2207	Transcriptional regulator
KAR29_03875	COG0784	Response regulator, receiver
KAR29_03875	COG2198	Histidine kinase
KAR29_03875	COG2205	protein histidine kinase activity
KAR29_03880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAR29_03895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KAR29_03910	COG0737	Belongs to the 5'-nucleotidase family
KAR29_03925	COG4565	transcriptional regulatory protein
KAR29_03930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAR29_03940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAR29_03945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAR29_03955	COG2199	diguanylate cyclase activity
KAR29_03955	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KAR29_03965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAR29_03980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KAR29_03985	COG0154	amidase activity
KAR29_03990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KAR29_03995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAR29_04000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KAR29_04005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAR29_04010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KAR29_04020	COG1555	photosystem II stabilization
KAR29_04025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAR29_04030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAR29_04045	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAR29_04045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAR29_04045	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAR29_04045	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAR29_04055	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAR29_04055	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAR29_04055	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAR29_04055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAR29_04080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAR29_04085	COG1773	rubredoxin
KAR29_04090	COG0006	proline dipeptidase activity
KAR29_04100	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KAR29_04105	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KAR29_04110	COG2770	Histidine kinase
KAR29_04110	COG3437	response regulator, receiver
KAR29_04130	COG0811	peptide transport
KAR29_04135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAR29_04140	COG0686	Belongs to the AlaDH PNT family
KAR29_04145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAR29_04150	COG1115	amino acid carrier protein
KAR29_04160	COG1737	Transcriptional regulator
KAR29_04180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAR29_04185	COG1473	amidohydrolase
KAR29_04210	COG3118	belongs to the thioredoxin family
KAR29_04220	COG0733	neurotransmitter:sodium symporter activity
KAR29_04225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAR29_04230	COG1692	metallophosphoesterase
KAR29_04235	COG1418	mRNA catabolic process
KAR29_04245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAR29_04250	COG3599	regulation of cell shape
KAR29_04255	COG1799	cell septum assembly
KAR29_04260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAR29_04275	COG0546	phosphoglycolate phosphatase activity
KAR29_04280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAR29_04285	COG0010	Belongs to the arginase family
KAR29_04325	COG1459	type II secretion system
KAR29_04385	COG0305	Participates in initiation and elongation during chromosome replication
KAR29_04390	COG0359	binds to the 23S rRNA
KAR29_04400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAR29_04405	COG0629	single-stranded DNA binding
KAR29_04410	COG0360	Binds together with S18 to 16S ribosomal RNA
KAR29_04420	COG0018	arginyl-trna synthetase
KAR29_04430	COG0653	protein targeting
KAR29_04445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_04450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAR29_04470	COG0559	Belongs to the binding-protein-dependent transport system permease family
KAR29_04480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAR29_04495	COG0537	adenosine 5'-monophosphoramidase activity
KAR29_04500	COG0484	heat shock protein binding
KAR29_04510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAR29_04520	COG2264	protein methyltransferase activity
KAR29_04525	COG0484	heat shock protein binding
KAR29_04530	COG0443	Heat shock 70 kDa protein
KAR29_04535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAR29_04540	COG1420	regulation of RNA biosynthetic process
KAR29_04550	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_04570	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAR29_04605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_04615	COG0066	3-isopropylmalate dehydratase activity
KAR29_04620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAR29_04625	COG2801	Transposase and inactivated derivatives
KAR29_04630	COG2801	Transposase and inactivated derivatives
KAR29_04635	COG1473	amidohydrolase
KAR29_04645	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KAR29_04655	COG1811	Na channel or pump
KAR29_04675	COG1024	Enoyl-CoA hydratase
KAR29_04680	COG1966	Carbon starvation protein
KAR29_04690	COG0583	DNA-binding transcription factor activity
KAR29_04695	COG2855	membrane
KAR29_04705	COG0582	viral genome integration into host DNA
KAR29_04800	COG0740	serine-type endopeptidase activity
KAR29_04825	COG0582	viral genome integration into host DNA
KAR29_04905	COG1396	sequence-specific DNA binding
KAR29_04935	COG1396	sequence-specific DNA binding
KAR29_05040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAR29_05060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAR29_05065	COG1120	ATPase activity
KAR29_05085	COG1151	hydroxylamine reductase activity
KAR29_05095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAR29_05105	COG0793	Belongs to the peptidase S41A family
KAR29_05110	COG0739	heme binding
KAR29_05115	COG2177	Part of the ABC transporter FtsEX involved in
KAR29_05120	COG2884	Cell division ATP-binding protein ftsE
KAR29_05125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAR29_05130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAR29_05145	COG0424	maF-like protein
KAR29_05155	COG1968	undecaprenyl-diphosphatase activity
KAR29_05165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KAR29_05170	COG0191	fructose-bisphosphate aldolase activity
KAR29_05195	COG0835	chemotaxis
KAR29_05200	COG0840	transmembrane signaling receptor activity
KAR29_05205	COG1473	amidohydrolase
KAR29_05210	COG1288	antiporter activity
KAR29_05215	COG1414	Transcriptional regulator
KAR29_05220	COG1802	Transcriptional regulator
KAR29_05225	COG0156	8-amino-7-oxononanoate synthase activity
KAR29_05230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAR29_05280	COG3391	amine dehydrogenase activity
KAR29_05295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAR29_05310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAR29_05315	COG0840	transmembrane signaling receptor activity
KAR29_05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KAR29_05335	COG2986	histidine ammonia-lyase
KAR29_05340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KAR29_05345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KAR29_05360	COG1794	racemase activity, acting on amino acids and derivatives
KAR29_05365	COG0384	phenazine biosynthesis protein PhzF
KAR29_05380	COG1414	Transcriptional regulator
KAR29_05385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAR29_05390	COG3314	Sporulation integral membrane protein YlbJ
KAR29_05395	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KAR29_05405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAR29_05415	COG1132	(ABC) transporter
KAR29_05440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAR29_05465	COG2801	Transposase and inactivated derivatives
KAR29_05470	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KAR29_05475	COG3180	Ammonia monooxygenase
KAR29_05510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_05520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_05530	COG2201	protein-glutamate methylesterase activity
KAR29_05560	COG0583	DNA-binding transcription factor activity
KAR29_05565	COG4948	Mandelate Racemase Muconate Lactonizing
KAR29_05580	COG0501	Belongs to the peptidase M48B family
KAR29_05590	COG0412	Dienelactone hydrolase
KAR29_05675	COG1918	ferrous iron import across plasma membrane
KAR29_05675	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAR29_05685	COG1473	amidohydrolase
KAR29_05690	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KAR29_05695	COG1288	antiporter activity
KAR29_05705	COG1757	Na H antiporter
KAR29_05710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAR29_05715	COG0542	response to heat
KAR29_05720	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KAR29_05730	COG4463	regulation of RNA biosynthetic process
KAR29_05735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KAR29_05760	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAR29_05765	COG1418	mRNA catabolic process
KAR29_05785	COG1151	hydroxylamine reductase activity
KAR29_05825	COG1132	(ABC) transporter
KAR29_05830	COG0390	transport system, permease component
KAR29_05840	COG1757	Na H antiporter
KAR29_05845	COG1802	Transcriptional regulator
KAR29_05855	COG2818	Glycosylase
KAR29_05880	COG2081	HI0933 family
KAR29_05910	COG0735	belongs to the Fur family
KAR29_05915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAR29_05935	COG0012	GTP binding
KAR29_05940	COG2056	Na+-H+ antiporter family
KAR29_05965	COG2186	Transcriptional regulator
KAR29_05975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAR29_05980	COG0066	3-isopropylmalate dehydratase activity
KAR29_05985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAR29_05990	COG0066	3-isopropylmalate dehydratase activity
KAR29_05995	COG0473	3-isopropylmalate dehydrogenase activity
KAR29_06020	COG2096	Adenosyltransferase
KAR29_06040	COG3206	protein involved in exopolysaccharide biosynthesis
KAR29_06055	COG0028	Belongs to the TPP enzyme family
KAR29_06075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAR29_06090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAR29_06095	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KAR29_06100	COG0438	transferase activity, transferring glycosyl groups
KAR29_06125	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_06140	COG1546	Belongs to the CinA family
KAR29_06140	COG1058	Belongs to the CinA family
KAR29_06145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KAR29_06150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KAR29_06160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KAR29_06165	COG2815	serine threonine protein kinase
KAR29_06165	COG0515	serine threonine protein kinase
KAR29_06170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAR29_06170	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KAR29_06180	COG2738	Putative neutral zinc metallopeptidase
KAR29_06190	COG1802	Transcriptional regulator
KAR29_06205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAR29_06220	COG1473	amidohydrolase
KAR29_06230	COG0564	pseudouridine synthase activity
KAR29_06235	COG3481	metal-dependent phosphohydrolase, HD sub domain
KAR29_06240	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
KAR29_06250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAR29_06260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_06285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAR29_06290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAR29_06295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAR29_06300	COG1288	antiporter activity
KAR29_06310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAR29_06330	COG2801	Transposase and inactivated derivatives
KAR29_06335	COG2801	Transposase and inactivated derivatives
KAR29_06345	COG2962	Rard protein
KAR29_06350	COG0402	S-adenosylhomocysteine deaminase activity
KAR29_06355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KAR29_06375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAR29_06410	COG2801	Transposase and inactivated derivatives
KAR29_06455	COG2801	Transposase and inactivated derivatives
KAR29_06495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAR29_06500	COG0556	nucleotide-excision repair
KAR29_06505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAR29_06510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAR29_06520	COG0736	holo-[acyl-carrier-protein] synthase activity
KAR29_06525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAR29_06525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAR29_06530	COG1121	(ABC) transporter
KAR29_06535	COG1214	PFAM Peptidase M22, glycoprotease
KAR29_06545	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_06560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAR29_06570	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAR29_06570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAR29_06575	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAR29_06585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KAR29_06590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAR29_06605	COG1269	ATP hydrolysis coupled proton transport
KAR29_06610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAR29_06620	COG1527	subunit (C
KAR29_06630	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KAR29_06650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KAR29_06660	COG2001	Belongs to the MraZ family
KAR29_06665	COG0275	rRNA processing
KAR29_06675	COG0768	penicillin binding
KAR29_06680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAR29_06685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAR29_06690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAR29_06695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAR29_06700	COG0772	Belongs to the SEDS family
KAR29_06705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAR29_06710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAR29_06715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAR29_06730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAR29_06740	COG0303	'Molybdopterin
KAR29_06750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAR29_06755	COG0315	cyclic pyranopterin monophosphate synthase activity
KAR29_06760	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAR29_06770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KAR29_06790	COG0126	phosphoglycerate kinase activity
KAR29_06795	COG0149	triose-phosphate isomerase activity
KAR29_06805	COG1316	TRANSCRIPTIONal
KAR29_06810	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAR29_06815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAR29_06820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAR29_06830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAR29_06840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAR29_06850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAR29_06860	COG1722	exodeoxyribonuclease VII activity
KAR29_06865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KAR29_06875	COG1674	ftsk spoiiie
KAR29_06880	COG0312	modulator of DNA gyrase
KAR29_06885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAR29_06890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAR29_06895	COG2986	histidine ammonia-lyase
KAR29_06905	COG2078	PFAM AMMECR1 domain protein
KAR29_06905	COG3885	ferrous iron binding
KAR29_06910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAR29_06915	COG2385	sporulation resulting in formation of a cellular spore
KAR29_06925	COG2255	four-way junction helicase activity
KAR29_06930	COG0632	four-way junction helicase activity
KAR29_06935	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KAR29_06940	COG0217	transcriptional regulatory protein
KAR29_06945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAR29_06950	COG0864	Transcriptional regulator
KAR29_06955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAR29_06965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KAR29_06970	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KAR29_06980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAR29_06985	COG4589	Belongs to the CDS family
KAR29_06990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAR29_06995	COG1573	uracil-dna glycosylase
KAR29_07000	COG2255	four-way junction helicase activity
KAR29_07005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAR29_07010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAR29_07015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAR29_07020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAR29_07025	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KAR29_07040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAR29_07060	COG0673	inositol 2-dehydrogenase activity
KAR29_07070	COG0285	dihydrofolate synthase activity
KAR29_07075	COG0525	valine-tRNA ligase activity
KAR29_07080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KAR29_07085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KAR29_07090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAR29_07095	COG0740	serine-type endopeptidase activity
KAR29_07100	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAR29_07115	COG0668	transmembrane transport
KAR29_07150	COG2801	Transposase and inactivated derivatives
KAR29_07170	COG4120	Belongs to the binding-protein-dependent transport system permease family
KAR29_07175	COG1116	anion transmembrane transporter activity
KAR29_07175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAR29_07185	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KAR29_07190	COG0564	pseudouridine synthase activity
KAR29_07195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAR29_07215	COG0196	riboflavin kinase activity
KAR29_07220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAR29_07225	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAR29_07230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAR29_07240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAR29_07255	COG0195	Participates in both transcription termination and antitermination
KAR29_07260	COG0779	Required for maturation of 30S ribosomal subunits
KAR29_07265	COG0516	GMP reductase activity
KAR29_07265	COG0517	IMP dehydrogenase activity
KAR29_07270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAR29_07275	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAR29_07275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KAR29_07280	COG4956	integral membrane protein (PIN domain superfamily)
KAR29_07285	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAR29_07290	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAR29_07295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAR29_07310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAR29_07315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAR29_07320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAR29_07320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAR29_07330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAR29_07330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAR29_07335	COG0322	excinuclease ABC activity
KAR29_07340	COG0215	cysteine-tRNA ligase activity
KAR29_07350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAR29_07355	COG0840	transmembrane signaling receptor activity
KAR29_07360	COG4968	Prepilin-type N-terminal cleavage methylation domain
KAR29_07365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAR29_07370	COG0720	synthase
KAR29_07385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAR29_07390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KAR29_07420	COG0494	nUDIX hydrolase
KAR29_07450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAR29_07460	COG0539	negative regulation of cytoplasmic translation
KAR29_07465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAR29_07470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAR29_07475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAR29_07480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAR29_07485	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAR29_07490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAR29_07495	COG0402	S-adenosylhomocysteine deaminase activity
KAR29_07500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KAR29_07505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KAR29_07510	COG1570	exodeoxyribonuclease VII activity
KAR29_07515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAR29_07535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAR29_07595	COG1459	type II secretion system
KAR29_07605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAR29_07635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAR29_07640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAR29_07640	COG0574	Belongs to the PEP-utilizing enzyme family
KAR29_07645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAR29_07650	COG0751	glycine-tRNA ligase activity
KAR29_07655	COG0752	glycyl-tRNA synthetase alpha subunit
KAR29_07665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KAR29_07670	COG0295	cytidine deaminase activity
KAR29_07675	COG4536	flavin adenine dinucleotide binding
KAR29_07680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAR29_07685	COG1480	7TM receptor with intracellular HD hydrolase
KAR29_07705	COG3956	TIGRFAM MazG family protein
KAR29_07710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAR29_07720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KAR29_07725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAR29_07730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAR29_07740	COG0735	belongs to the Fur family
KAR29_07755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAR29_07760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAR29_07765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAR29_07775	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KAR29_07785	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KAR29_07790	COG0494	nUDIX hydrolase
KAR29_07810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KAR29_07815	COG0501	Belongs to the peptidase M48B family
KAR29_07835	COG0517	IMP dehydrogenase activity
KAR29_07835	COG0617	tRNA 3'-terminal CCA addition
KAR29_07835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KAR29_07840	COG1105	Belongs to the carbohydrate kinase PfkB family
KAR29_07850	COG2890	protein-(glutamine-N5) methyltransferase activity
KAR29_07855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAR29_07860	COG3872	metal-dependent enzyme
KAR29_07865	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KAR29_07880	COG2801	Transposase and inactivated derivatives
KAR29_07890	COG2358	TRAP transporter, solute receptor (TAXI family
KAR29_07905	COG2801	Transposase and inactivated derivatives
KAR29_07910	COG2801	Transposase and inactivated derivatives
KAR29_07935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAR29_07940	COG0252	asparaginase activity
KAR29_07970	COG3260	NADH ubiquinone oxidoreductase 20
KAR29_07980	COG0651	ATP synthesis coupled electron transport
KAR29_08025	COG1193	negative regulation of DNA recombination
KAR29_08045	COG0072	phenylalanine-tRNA ligase activity
KAR29_08050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAR29_08055	COG0569	domain protein
KAR29_08060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KAR29_08065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAR29_08075	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAR29_08080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAR29_08085	COG0733	neurotransmitter:sodium symporter activity
KAR29_08095	COG1185	polyribonucleotide nucleotidyltransferase activity
KAR29_08100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAR29_08105	COG0745	RESPONSE REGULATOR receiver
KAR29_08125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAR29_08130	COG3852	Histidine kinase
KAR29_08135	COG2204	response regulator
KAR29_08145	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KAR29_08150	COG1914	H( )-stimulated, divalent metal cation uptake system
KAR29_08155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KAR29_08160	COG1984	allophanate hydrolase subunit 2
KAR29_08165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KAR29_08170	COG4336	lyase activity
KAR29_08175	COG1683	Conserved Protein
KAR29_08190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAR29_08195	COG1027	Aspartate ammonia-lyase
KAR29_08200	COG0745	RESPONSE REGULATOR receiver
KAR29_08205	COG2205	protein histidine kinase activity
KAR29_08205	COG2198	Histidine kinase
KAR29_08205	COG0784	Response regulator, receiver
KAR29_08215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KAR29_08240	COG1598	PFAM Uncharacterised protein family UPF0150
KAR29_08250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAR29_08290	COG0281	malic enzyme
KAR29_08315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KAR29_08320	COG2197	response regulator
KAR29_08325	COG0037	tRNA processing
KAR29_08340	COG0719	Fe-S assembly protein
KAR29_08345	COG0396	ATPase activity
KAR29_08350	COG0166	Belongs to the GPI family
KAR29_08355	COG0543	2 iron, 2 sulfur cluster binding
KAR29_08370	COG2326	polyphosphate kinase activity
KAR29_08375	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAR29_08385	COG0235	Class ii aldolase
KAR29_08390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_08390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_08400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_08415	COG1830	Aldolase
KAR29_08435	COG2084	Dehydrogenase
KAR29_08440	COG1032	radical SAM domain protein
KAR29_08445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KAR29_08460	COG0183	Belongs to the thiolase family
KAR29_08465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KAR29_08470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KAR29_08480	COG2358	TRAP transporter, solute receptor (TAXI family
KAR29_08485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAR29_08510	COG2201	protein-glutamate methylesterase activity
KAR29_08515	COG2801	Transposase and inactivated derivatives
KAR29_08535	COG2119	membrane
KAR29_08540	COG0628	permease
KAR29_08565	COG1847	R3H domain protein
KAR29_08570	COG0706	membrane insertase activity
KAR29_08575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KAR29_08580	COG0594	ribonuclease P activity
KAR29_08585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KAR29_08590	COG2801	Transposase and inactivated derivatives
KAR29_08595	COG1199	ATP-dependent helicase activity
KAR29_08600	COG0268	Binds directly to 16S ribosomal RNA
KAR29_08610	COG0495	leucyl-tRNA aminoacylation
KAR29_08615	COG0330	HflC and HflK could
KAR29_08625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAR29_08630	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KAR29_08635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAR29_08640	COG0131	Imidazoleglycerol-phosphate dehydratase
KAR29_08645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAR29_08650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAR29_08655	COG0107	imidazoleglycerol-phosphate synthase activity
KAR29_08670	COG1288	antiporter activity
KAR29_08680	COG0613	PHP domain protein
KAR29_08720	COG1609	Transcriptional regulator
KAR29_08740	COG4177	L-phenylalanine transmembrane transporter activity
KAR29_08775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAR29_08815	COG2089	acid synthase
KAR29_08820	COG1086	Polysaccharide biosynthesis protein
KAR29_08825	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KAR29_08835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAR29_08860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAR29_08885	COG1040	competence protein
KAR29_08890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KAR29_08895	COG0454	-acetyltransferase
KAR29_08905	COG4372	Transposase
KAR29_08930	COG1706	bacterial-type flagellum-dependent cell motility
KAR29_08935	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAR29_08950	COG4786	Flagellar basal body rod
KAR29_08955	COG1077	Cell shape determining protein MreB Mrl
KAR29_08960	COG0101	tRNA pseudouridine synthase activity
KAR29_08965	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAR29_08970	COG1122	ATPase activity
KAR29_08975	COG1122	ATPase activity
KAR29_08980	COG0203	ribosomal protein L17
KAR29_08985	COG0202	RNA polymerase activity
KAR29_08990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAR29_08995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAR29_09000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAR29_09010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAR29_09020	COG0563	adenylate kinase activity
KAR29_09025	COG0201	protein transport
KAR29_09030	COG0200	Binds to the 23S rRNA
KAR29_09035	COG1841	ribosomal large subunit assembly
KAR29_09040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAR29_09045	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAR29_09050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAR29_09055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAR29_09060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAR29_09070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAR29_09075	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAR29_09080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAR29_09090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAR29_09095	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAR29_09100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAR29_09105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAR29_09110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAR29_09115	COG0089	rRNA binding
KAR29_09120	COG0088	Forms part of the polypeptide exit tunnel
KAR29_09125	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAR29_09130	COG0051	transcription antitermination factor activity, RNA binding
KAR29_09140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAR29_09145	COG0049	tRNA binding
KAR29_09150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAR29_09155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAR29_09155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAR29_09160	COG0085	RNA polymerase activity
KAR29_09170	COG2801	Transposase and inactivated derivatives
KAR29_09180	COG0009	L-threonylcarbamoyladenylate synthase
KAR29_09185	COG0343	queuine tRNA-ribosyltransferase activity
KAR29_09190	COG0084	hydrolase, TatD family'
KAR29_09215	COG1192	Involved in chromosome partitioning
KAR29_09225	COG1196	nuclear chromosome segregation
KAR29_09245	COG0772	Belongs to the SEDS family
KAR29_09250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAR29_09255	COG2894	cell division
KAR29_09260	COG0850	regulation of cytokinetic process
KAR29_09280	COG1077	Cell shape determining protein MreB Mrl
KAR29_09285	COG2003	Belongs to the UPF0758 family
KAR29_09290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAR29_09295	COG1490	D-aminoacyl-tRNA deacylase activity
KAR29_09300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAR29_09305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KAR29_09305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KAR29_09320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAR29_09325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAR29_09330	COG1862	Preprotein translocase
KAR29_09335	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KAR29_09340	COG0148	phosphopyruvate hydratase activity
KAR29_09345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KAR29_09355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAR29_09360	COG0358	DNA primase activity
KAR29_09365	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KAR29_09375	COG0628	permease
KAR29_09395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAR29_09395	COG0519	Catalyzes the synthesis of GMP from XMP
KAR29_09400	COG0459	protein refolding
KAR29_09405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAR29_09410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAR29_09420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAR29_09445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAR29_09455	COG0083	homoserine kinase activity
KAR29_09460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAR29_09465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAR29_09470	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAR29_09500	COG0504	CTP synthase activity
KAR29_09505	COG0739	heme binding
KAR29_09510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KAR29_09515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAR29_09545	COG0546	phosphoglycolate phosphatase activity
KAR29_09565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KAR29_09570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAR29_09570	COG4191	Histidine kinase
KAR29_09585	COG0058	SHG alpha-glucan phosphorylase activity
KAR29_09590	COG0297	glycogen (starch) synthase activity
KAR29_09595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAR29_09610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAR29_09615	COG1454	alcohol dehydrogenase
KAR29_09620	COG1519	Transferase
KAR29_09630	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KAR29_09635	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KAR29_09640	COG1663	tetraacyldisaccharide 4'-kinase activity
KAR29_09645	COG1132	(ABC) transporter
KAR29_09655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAR29_09670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAR29_09675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAR29_09680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAR29_09685	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAR29_09690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAR29_09710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAR29_09715	COG0406	alpha-ribazole phosphatase activity
KAR29_09735	COG0165	Argininosuccinate lyase
KAR29_09740	COG0248	Ppx GppA phosphatase
KAR29_09775	COG1191	sigma factor activity
KAR29_09785	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KAR29_09790	COG1776	CheC inhibitor of MCP methylation
KAR29_09795	COG0643	Histidine kinase
KAR29_09795	COG2198	Histidine kinase
KAR29_09800	COG2201	protein-glutamate methylesterase activity
KAR29_09815	COG1419	protein localization to endoplasmic reticulum
KAR29_09820	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAR29_09825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAR29_09830	COG1684	flagellar biosynthetic protein fliR
KAR29_09835	COG1987	bacterial-type flagellum assembly
KAR29_09840	COG1338	Plays a role in the flagellum-specific transport system
KAR29_09850	COG2201	protein-glutamate methylesterase activity
KAR29_09855	COG1776	CheC inhibitor of MCP methylation
KAR29_09855	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAR29_09860	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAR29_09905	COG0741	lytic transglycosylase activity
KAR29_09915	COG1157	protein secretion by the type III secretion system
KAR29_09925	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KAR29_09930	COG1766	The M ring may be actively involved in energy transduction
KAR29_09935	COG1677	Flagellar hook-basal body complex protein FliE
KAR29_09955	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAR29_09960	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KAR29_09970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KAR29_09975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAR29_09995	COG0792	nuclease activity
KAR29_10015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAR29_10020	COG0681	Belongs to the peptidase S26 family
KAR29_10040	COG0824	Thioesterase
KAR29_10075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_10080	COG0601	transmembrane transport
KAR29_10085	COG4166	transmembrane transport
KAR29_10095	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KAR29_10110	COG1691	(AIR) carboxylase
KAR29_10115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAR29_10125	COG0189	ligase activity
KAR29_10130	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
KAR29_10140	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
KAR29_10165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAR29_10165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAR29_10190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAR29_10200	COG0531	amino acid
KAR29_10210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAR29_10210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KAR29_10210	COG1013	pyruvate-flavodoxin oxidoreductase activity
KAR29_10210	COG0674	pyruvate-flavodoxin oxidoreductase activity
KAR29_10215	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
KAR29_10220	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KAR29_10255	COG1394	ATPase activity, coupled to movement of substances
KAR29_10260	COG0697	spore germination
KAR29_10280	COG0346	lactoylglutathione lyase activity
KAR29_10295	COG0303	'Molybdopterin
KAR29_10310	COG2226	methyltransferase
KAR29_10320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KAR29_10325	COG1120	ATPase activity
KAR29_10330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAR29_10360	COG0335	large ribosomal subunit rRNA binding
KAR29_10365	COG0336	Belongs to the RNA methyltransferase TrmD family
KAR29_10370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAR29_10380	COG0228	four-way junction DNA binding
KAR29_10385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAR29_10390	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KAR29_10405	COG1902	pentaerythritol trinitrate reductase activity
KAR29_10410	COG1902	pentaerythritol trinitrate reductase activity
KAR29_10420	COG2076	Multidrug Resistance protein
KAR29_10430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAR29_10440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAR29_10440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAR29_10450	COG0726	polysaccharide deacetylase
KAR29_10470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAR29_10475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAR29_10480	COG0124	histidyl-tRNA synthetase
KAR29_10485	COG2359	stage V sporulation protein S
KAR29_10495	COG3123	guanosine phosphorylase activity
KAR29_10500	COG1376	ErfK ybiS ycfS ynhG family protein
KAR29_10505	COG1126	abc transporter atp-binding protein
KAR29_10510	COG0765	amino acid transport
KAR29_10535	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_10545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAR29_10565	COG1129	ABC transporter
KAR29_10570	COG1609	Transcriptional regulator
KAR29_10575	COG1803	Methylglyoxal synthase
KAR29_10580	COG0697	spore germination
KAR29_10595	COG2212	antiporter activity
KAR29_10600	COG1320	monovalent cation:proton antiporter activity
KAR29_10605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KAR29_10605	COG2111	Na H antiporter
KAR29_10615	COG0713	ATP synthesis coupled electron transport
KAR29_10620	COG0651	ATP synthesis coupled electron transport
KAR29_10635	COG0330	HflC and HflK could
KAR29_10650	COG1785	Belongs to the alkaline phosphatase family
KAR29_10660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAR29_10665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAR29_10670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAR29_10675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KAR29_10685	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KAR29_10690	COG2801	Transposase and inactivated derivatives
KAR29_10695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KAR29_10715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAR29_10715	COG4651	solute:proton antiporter activity
KAR29_10730	COG0159	tryptophan synthase activity
KAR29_10740	COG0135	phosphoribosylanthranilate isomerase activity
KAR29_10745	COG0134	indole-3-glycerol-phosphate synthase activity
KAR29_10750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAR29_10755	COG0512	Glutamine amidotransferase of anthranilate synthase
KAR29_10755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAR29_10760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAR29_10775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KAR29_10790	COG3459	Glycosyltransferase 36 associated
KAR29_10845	COG1111	helicase
KAR29_10845	COG1205	dead DEAH box helicase
KAR29_10850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAR29_10870	COG0833	amino acid
KAR29_10875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAR29_10880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAR29_10885	COG0786	glutamate:sodium symporter activity
KAR29_10920	COG0514	ATP-dependent DNA helicase (RecQ)
KAR29_10925	COG1115	amino acid carrier protein
KAR29_10945	COG1802	Transcriptional regulator
KAR29_10955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_10955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_10960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_10960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAR29_11000	COG1757	Na H antiporter
KAR29_11005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAR29_11015	COG0531	amino acid
KAR29_11020	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KAR29_11025	COG0371	Dehydrogenase
KAR29_11065	COG0577	efflux transmembrane transporter activity
KAR29_11065	COG1136	(ABC) transporter
KAR29_11070	COG5001	Diguanylate cyclase
KAR29_11085	COG0534	Mate efflux family protein
KAR29_11110	COG2801	Transposase and inactivated derivatives
KAR29_11165	COG0436	Aminotransferase
KAR29_11175	COG0800	Aldolase
KAR29_11180	COG1414	Transcriptional regulator
KAR29_11200	COG0531	amino acid
KAR29_11220	COG3620	sequence-specific DNA binding
KAR29_11250	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KAR29_11280	COG0438	transferase activity, transferring glycosyl groups
KAR29_11310	COG2801	Transposase and inactivated derivatives
KAR29_11345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAR29_11355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KAR29_11365	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAR29_11385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KAR29_11440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAR29_11445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAR29_11460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_11485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KAR29_11490	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KAR29_11495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAR29_11500	COG1120	ATPase activity
KAR29_11510	COG1918	ferrous iron import across plasma membrane
KAR29_11510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KAR29_11525	COG2201	protein-glutamate methylesterase activity
KAR29_11530	COG0725	ABC transporter, periplasmic molybdate-binding protein
KAR29_11535	COG3842	ATPase activity
KAR29_11540	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAR29_11550	COG4662	Binding-protein-dependent transport system inner membrane component
KAR29_11560	COG2998	abc-type tungstate transport system, permease component
KAR29_11565	COG0528	UMP kinase activity
KAR29_11580	COG1012	belongs to the aldehyde dehydrogenase family
KAR29_11600	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KAR29_11615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAR29_11620	COG1205	dead DEAH box helicase
KAR29_11620	COG1111	helicase
KAR29_11635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAR29_11635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAR29_11640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAR29_11650	COG4608	Belongs to the ABC transporter superfamily
KAR29_11655	COG0444	Belongs to the ABC transporter superfamily
KAR29_11660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KAR29_11665	COG0601	transmembrane transport
KAR29_11670	COG0747	negative chemotaxis
KAR29_11680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_11685	COG3706	GGDEF domain
KAR29_11690	COG4187	Peptidase family M20/M25/M40
KAR29_11700	COG2848	UPF0210 protein
KAR29_11710	COG3314	Sporulation integral membrane protein YlbJ
KAR29_11715	COG3875	lactate racemase activity
KAR29_11720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KAR29_11725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KAR29_11735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_11740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAR29_11750	COG0251	oxidation-reduction process
KAR29_11755	COG0733	neurotransmitter:sodium symporter activity
KAR29_11765	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KAR29_11775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAR29_11780	COG2045	Belongs to the ComB family
KAR29_11795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KAR29_11800	COG1410	methionine synthase
KAR29_11800	COG0646	methionine synthase
KAR29_11820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_11840	COG0438	transferase activity, transferring glycosyl groups
KAR29_11845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAR29_11845	COG0561	phosphatase activity
KAR29_11855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_11855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_11860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_11860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_11865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_11870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAR29_11875	COG1802	Transcriptional regulator
KAR29_11880	COG2086	electron transfer activity
KAR29_11885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KAR29_11890	COG0277	FAD linked oxidase domain protein
KAR29_11905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAR29_11930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KAR29_11940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAR29_11945	COG1882	Formate acetyltransferase
KAR29_11965	COG1882	Formate acetyltransferase
KAR29_11975	COG2195	Cleaves the N-terminal amino acid of tripeptides
KAR29_11980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAR29_11985	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KAR29_11990	COG4656	Part of a membrane complex involved in electron transport
KAR29_12005	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
KAR29_12020	COG4820	ethanolamine utilization protein (EutJ)
KAR29_12075	COG4810	utilization protein
KAR29_12085	COG3275	phosphorelay sensor kinase activity
KAR29_12090	COG1454	alcohol dehydrogenase
KAR29_12095	COG1802	Transcriptional regulator
KAR29_12115	COG2986	histidine ammonia-lyase
KAR29_12125	COG0477	Major facilitator Superfamily
KAR29_12130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KAR29_12135	COG3829	transcription factor binding
KAR29_12135	COG3290	protein histidine kinase activity
KAR29_12165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAR29_12190	COG0179	Fumarylacetoacetate (FAA) hydrolase
KAR29_12200	COG1196	nuclear chromosome segregation
KAR29_12205	COG0784	Response regulator, receiver
KAR29_12205	COG3437	response regulator, receiver
KAR29_12210	COG0442	prolyl-tRNA aminoacylation
KAR29_12225	COG3191	aminopeptidase activity
KAR29_12240	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_12245	COG2186	Transcriptional regulator
KAR29_12250	COG0579	oxidoreductase
KAR29_12255	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAR29_12265	COG1234	tRNA 3'-trailer cleavage
KAR29_12270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAR29_12295	COG2801	Transposase and inactivated derivatives
KAR29_12300	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KAR29_12310	COG0716	FMN binding
KAR29_12325	COG0822	iron-sulfur transferase activity
KAR29_12335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAR29_12340	COG1760	l-serine dehydratase
KAR29_12345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAR29_12350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAR29_12360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_12370	COG2423	ornithine cyclodeaminase activity
KAR29_12380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_12380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_12390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_12405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAR29_12425	COG1827	regulation of RNA biosynthetic process
KAR29_12450	COG0028	Belongs to the TPP enzyme family
KAR29_12460	COG3069	C4-dicarboxylate transmembrane transporter activity
KAR29_12505	COG2936	dipeptidyl-peptidase activity
KAR29_12515	COG1802	Transcriptional regulator
KAR29_12535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_12535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_12555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAR29_12570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAR29_12580	COG2204	response regulator
KAR29_12630	COG1353	crispr-associated protein
KAR29_12640	COG1337	RAMP superfamily
KAR29_12665	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KAR29_12690	COG1518	maintenance of DNA repeat elements
KAR29_12700	COG2379	hydroxypyruvate reductase
KAR29_12705	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KAR29_12715	COG1473	amidohydrolase
KAR29_12730	COG1131	(ABC) transporter
KAR29_12745	COG2731	YhcH YjgK YiaL family protein
KAR29_12750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KAR29_12770	COG0784	Response regulator, receiver
KAR29_12770	COG5002	protein histidine kinase activity
KAR29_12770	COG2205	protein histidine kinase activity
KAR29_12775	COG0584	glycerophosphoryl diester phosphodiesterase
KAR29_12780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAR29_12785	COG3842	ATPase activity
KAR29_12790	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAR29_12795	COG1177	transmembrane transport
KAR29_12805	COG2770	Histidine kinase
KAR29_12805	COG3437	response regulator, receiver
KAR29_12825	COG2186	Transcriptional regulator
KAR29_12830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_12840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_12840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_12845	COG0129	dihydroxy-acid dehydratase activity
KAR29_12855	COG4895	conserved protein (DUF2196)
KAR29_12885	COG4942	peptidase
KAR29_12915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_12915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_12920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_12920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_12925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_12940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAR29_12945	COG1802	Transcriptional regulator
KAR29_12950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KAR29_12965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAR29_12970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAR29_12980	COG0071	Belongs to the small heat shock protein (HSP20) family
KAR29_13000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_13010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_13010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_13030	COG0640	Transcriptional regulator
KAR29_13045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAR29_13050	COG1802	Transcriptional regulator
KAR29_13060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KAR29_13170	COG0352	thiamine-phosphate diphosphorylase activity
KAR29_13180	COG0351	phosphomethylpyrimidine kinase
KAR29_13185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAR29_13195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KAR29_13200	COG1116	anion transmembrane transporter activity
KAR29_13230	COG0436	Aminotransferase
KAR29_13240	COG2801	Transposase and inactivated derivatives
KAR29_13245	COG1408	metallophosphoesterase
KAR29_13255	COG1477	protein flavinylation
KAR29_13270	COG2878	Part of a membrane complex involved in electron transport
KAR29_13275	COG4657	Part of a membrane complex involved in electron transport
KAR29_13280	COG4660	Part of a membrane complex involved in electron transport
KAR29_13285	COG4659	FMN binding
KAR29_13290	COG4658	electron transport chain
KAR29_13295	COG4656	Part of a membrane complex involved in electron transport
KAR29_13300	COG0006	proline dipeptidase activity
KAR29_13310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KAR29_13335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAR29_13345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KAR29_13345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KAR29_13350	COG4187	Peptidase family M20/M25/M40
KAR29_13395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAR29_13445	COG0840	transmembrane signaling receptor activity
KAR29_13460	COG0840	transmembrane signaling receptor activity
KAR29_13465	COG2183	response to ionizing radiation
KAR29_13475	COG0651	ATP synthesis coupled electron transport
KAR29_13480	COG0650	Formate hydrogenlyase subunit 4
KAR29_13490	COG0651	ATP synthesis coupled electron transport
KAR29_13500	COG3260	NADH ubiquinone oxidoreductase 20
KAR29_13525	COG0668	transmembrane transport
KAR29_13535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KAR29_13540	COG0573	inorganic phosphate transmembrane transporter activity
KAR29_13545	COG0581	inorganic phosphate transmembrane transporter activity
KAR29_13550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KAR29_13555	COG0704	Plays a role in the regulation of phosphate uptake
KAR29_13560	COG0745	RESPONSE REGULATOR receiver
KAR29_13565	COG5002	protein histidine kinase activity
KAR29_13585	COG0840	transmembrane signaling receptor activity
KAR29_13610	COG2894	cell division
KAR29_13625	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KAR29_13630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAR29_13635	COG1120	ATPase activity
KAR29_13640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAR29_13640	COG0731	radical SAM domain protein
KAR29_13680	COG0148	phosphopyruvate hydratase activity
KAR29_13685	COG1993	acr, cog1993
KAR29_13695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAR29_13715	COG0133	tryptophan synthase activity
KAR29_13735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAR29_13740	COG0318	PFAM AMP-dependent synthetase and ligase
KAR29_13770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAR29_13775	COG1125	glycine betaine transport
KAR29_13775	COG0517	IMP dehydrogenase activity
KAR29_13790	COG2414	aldehyde ferredoxin oxidoreductase
KAR29_13795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAR29_13805	COG2508	Transcriptional regulator
KAR29_13810	COG1288	antiporter activity
KAR29_13835	COG2190	(PTS) system
KAR29_13845	COG0363	glucosamine-6-phosphate deaminase activity
KAR29_13855	COG1263	PTS System
KAR29_13855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KAR29_13855	COG2190	(PTS) system
KAR29_13860	COG2188	Transcriptional regulator
KAR29_13865	COG1309	transcriptional regulator
KAR29_13870	COG4953	penicillin-binding protein 1C
KAR29_13890	COG2197	response regulator
KAR29_13920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAR29_13930	COG2860	membrane