locus-tag	class	description
Sfum_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Sfum_0002	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Sfum_0005	ENOG4105D0M	Protease HtpX homolog
Sfum_0006	ENOG4105C2X	Arabinose 5-phosphate isomerase
Sfum_0008	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Sfum_0009	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Sfum_0010	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Sfum_0011	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Sfum_0014	ENOG4105BZ8	glutamate synthase
Sfum_0016	ENOG4105DQU	oxidoreductase, subunit beta
Sfum_0017	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Sfum_0020	ENOG4105DAN	ATP-dependent protease
Sfum_0030	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Sfum_0031	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Sfum_0032	ENOG4105CEV	competence damage-inducible protein
Sfum_0034	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Sfum_0035	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Sfum_0041	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Sfum_0042	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Sfum_0044	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Sfum_0047	ENOG4105C5B	carbamate kinase
Sfum_0049	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Sfum_0050	ENOG4105E4C	Lytic transglycosylase catalytic
Sfum_0051	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Sfum_0054	ENOG4105CHM	Aminotransferase
Sfum_0055	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Sfum_0056	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Sfum_0057	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Sfum_0058	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Sfum_0060	ENOG4105CH7	arginosuccinase
Sfum_0061	ENOG4105CDH	Citrulline--aspartate ligase
Sfum_0062	ENOG4105DBV	ornithine carbamoyltransferase
Sfum_0063	ENOG4105C8Y	Acetylornithine aminotransferase
Sfum_0064	ENOG4105CAS	nag kinase
Sfum_0065	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Sfum_0066	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Sfum_0067	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Sfum_0068	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Sfum_0070	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Sfum_0076	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
Sfum_0077	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Sfum_0078	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Sfum_0079	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Sfum_0080	ENOG4107QR9	Iron-sulfur cluster binding protein
Sfum_0081	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
Sfum_0084	ENOG4105VFU	Rna-binding protein
Sfum_0094	ENOG4105CSH	Transporter
Sfum_0098	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Sfum_0099	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Sfum_0100	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Sfum_0101	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Sfum_0102	ENOG4108VAU	general secretion pathway protein G
Sfum_0103	ENOG4105N5T	Radical SAM Protein
Sfum_0104	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Sfum_0106	ENOG4105BZJ	Electron transfer flavoprotein
Sfum_0107	ENOG4105C10	Electron transfer flavoprotein
Sfum_0108	ENOG4105CEY	Amp-dependent synthetase and ligase
Sfum_0111	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Sfum_0112	ENOG4105CHR	reductase
Sfum_0113	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Sfum_0114	ENOG4105DDK	oxidoreductase, beta subunit
Sfum_0115	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Sfum_0117	ENOG4107QHF	type ii secretion system protein e
Sfum_0119	ENOG4105BZU	Histidine kinase
Sfum_0120	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Sfum_0121	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Sfum_0122	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Sfum_0123	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Sfum_0128	ENOG4105CND	Glycosyl transferase, family 2
Sfum_0132	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Sfum_0147	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Sfum_0148	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Sfum_0150	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Sfum_0151	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Sfum_0154	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Sfum_0155	ENOG4105MA4	psp1 domain protein
Sfum_0157	ENOG4105EQI	Metal Dependent Phosphohydrolase
Sfum_0160	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Sfum_0161	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Sfum_0166	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Sfum_0167	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Sfum_0168	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Sfum_0169	ENOG4105DC7	peptidase M24
Sfum_0184	ENOG4107RIZ	hflk protein
Sfum_0185	ENOG4105EPW	hflc protein
Sfum_0186	ENOG4106J7S	Glycosyl transferase, family 2
Sfum_0187	ENOG410812K	response regulator receiver protein
Sfum_0188	ENOG4108K5H	permease YjgP YjgQ family protein
Sfum_0190	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Sfum_0192	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Sfum_0193	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Sfum_0194	ENOG4108UMN	azlc family
Sfum_0196	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Sfum_0200	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_0201	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Sfum_0202	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_0203	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Sfum_0204	ENOG4107X8D	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_0206	ENOG4107EJQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_0208	ENOG4105C8S	subunit m
Sfum_0209	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_0211	ENOG4105CFP	Peptidase U32
Sfum_0213	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Sfum_0215	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Sfum_0226	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Sfum_0227	ENOG4105E09	nadh pyrophosphatase
Sfum_0228	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Sfum_0230	ENOG4108UT2	hemolysin iii
Sfum_0234	ENOG4108YXV	Transcriptional regulator
Sfum_0238	ENOG4105CVJ	phosphoglycerate mutase
Sfum_0240	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
Sfum_0242	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Sfum_0252	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_0253	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_0255	ENOG4107RBB	ABC transporter, permease
Sfum_0258	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Sfum_0260	ENOG4105CFG	Acts as a chaperone (By similarity)
Sfum_0263	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Sfum_0264	ENOG41080HT	Transcriptional regulator, arsr family
Sfum_0266	ENOG41089UC	methyltransferase, type 11
Sfum_0272	ENOG4105EMN	RNA polymerase sigma factor
Sfum_0277	ENOG4105EWA	aspartate glutamate uridylate kinase
Sfum_0280	ENOG4108XC3	NADH ubiquinone oxidoreductase
Sfum_0283	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Sfum_0284	ENOG4105E2Z	phosphate ABC transporter (Permease
Sfum_0285	ENOG4105C8U	phosphate abc transporter
Sfum_0286	ENOG4107S17	Phosphate-binding protein
Sfum_0287	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Sfum_0289	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Sfum_0290	ENOG4105BZ4	penicillin-binding protein
Sfum_0292	ENOG4105F4G	Membrane
Sfum_0294	ENOG4105BZU	Histidine kinase
Sfum_0297	ENOG4105CEY	Amp-dependent synthetase and ligase
Sfum_0298	ENOG4105CPC	Aldo Keto reductase
Sfum_0301	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Sfum_0303	ENOG4108JUB	Transcriptional regulator
Sfum_0306	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Sfum_0308	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Sfum_0309	ENOG4105W87	Cbs domain
Sfum_0310	ENOG4108IV0	ABC, transporter
Sfum_0311	ENOG4105C0Z	ABC transporter
Sfum_0314	ENOG41083Z3	extracellular ligand-binding receptor
Sfum_0318	ENOG4105CXV	gliding motility protein
Sfum_0323	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Sfum_0338	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Sfum_0339	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Sfum_0340	ENOG4107ZS6	Flavodoxin
Sfum_0343	ENOG4105CFG	Acts as a chaperone (By similarity)
Sfum_0346	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Sfum_0350	ENOG4108YXV	Transcriptional regulator
Sfum_0356	ENOG4105C01	Dihydroxy-acid dehydratase
Sfum_0360	ENOG4105KNI	merR family transcriptional Regulator
Sfum_0361	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sfum_0365	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Sfum_0366	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Sfum_0367	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Sfum_0368	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Sfum_0369	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Sfum_0370	ENOG4105DKP	glycosyl transferase, family 9
Sfum_0371	ENOG4105DKP	glycosyl transferase, family 9
Sfum_0372	ENOG4105DKP	glycosyl transferase, family 9
Sfum_0373	ENOG4107SBE	Glycosyl transferase (Group 1
Sfum_0374	ENOG4106WTF	Glycosyl transferase, family 2
Sfum_0375	ENOG4105D16	lipopolysaccharide heptosyltransferase i
Sfum_0376	ENOG4105D1S	lipid A biosynthesis
Sfum_0377	ENOG4105XA0	heptosyltransferase ii
Sfum_0379	ENOG4105DZS	Phenylacetate-CoA ligase
Sfum_0380	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Sfum_0381	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
Sfum_0382	ENOG4105DZS	Phenylacetate-CoA ligase
Sfum_0383	ENOG4108IV0	ABC, transporter
Sfum_0384	ENOG4105C0Z	ABC transporter
Sfum_0385	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_0388	ENOG4105CYC	Transferase
Sfum_0389	ENOG4105CYC	Transferase
Sfum_0390	ENOG4107QR9	Iron-sulfur cluster binding protein
Sfum_0392	ENOG4105CQB	FAD linked oxidase domain protein
Sfum_0393	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Sfum_0398	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Sfum_0400	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Sfum_0401	ENOG4105DHJ	ABC, transporter
Sfum_0402	ENOG4105CY3	ABC transporter, permease
Sfum_0405	ENOG4105DGU	Histone deacetylase
Sfum_0406	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Sfum_0411	ENOG4105C0D	helicase
Sfum_0414	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Sfum_0417	ENOG4105CPN	adenine deaminase
Sfum_0419	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Sfum_0423	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Sfum_0424	ENOG4105C22	threonyL-tRNA synthetase
Sfum_0425	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Sfum_0426	ENOG4105VJV	50s ribosomal protein L35
Sfum_0427	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Sfum_0428	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Sfum_0429	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Sfum_0431	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Sfum_0432	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Sfum_0433	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Sfum_0434	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Sfum_0438	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Sfum_0439	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Sfum_0446	ENOG4105PF9	Transcriptional regulator
Sfum_0448	ENOG4107RUY	(E1 component), alpha subunit
Sfum_0449	ENOG4105CPP	Dehydrogenase, E1 component
Sfum_0450	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Sfum_0451	ENOG4105BZS	acriflavin resistance protein
Sfum_0452	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Sfum_0454	ENOG4107T5V	SNARE associated Golgi
Sfum_0455	ENOG4108ZVT	methylmalonyl-coA epimerase
Sfum_0460	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Sfum_0461	ENOG4107QSA	Oxaloacetate decarboxylase
Sfum_0464	ENOG4107QX8	SPFH domain, Band 7 family protein
Sfum_0466	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Sfum_0467	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Sfum_0469	ENOG4105C5X	domain protein
Sfum_0472	ENOG4105DHJ	ABC, transporter
Sfum_0476	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
Sfum_0478	ENOG4105C6T	cysteine synthase
Sfum_0483	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Sfum_0484	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Sfum_0485	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Sfum_0486	ENOG41068JE	domain protein
Sfum_0487	ENOG41082T9	Membrane
Sfum_0489	ENOG4105DKQ	ROK family
Sfum_0492	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Sfum_0493	ENOG4105S10	periplasmic binding protein
Sfum_0494	ENOG4108I9K	permease protein
Sfum_0495	ENOG4105E0A	ABC, transporter
Sfum_0496	ENOG4105CTK	cobaltochelatase, cobn subunit
Sfum_0497	ENOG4105EET	magnesium chelatase
Sfum_0500	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Sfum_0502	ENOG4105C4R	Atp-dependent dna helicase
Sfum_0504	ENOG4108YXV	Transcriptional regulator
Sfum_0509	ENOG4108UQS	dipeptidase
Sfum_0510	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Sfum_0517	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Sfum_0519	ENOG4105DCT	glycerol dehydrogenase
Sfum_0520	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Sfum_0522	ENOG4105CHR	reductase
Sfum_0532	ENOG4105EHM	Aminoglycoside phosphotransferase
Sfum_0534	ENOG4105CQB	FAD linked oxidase domain protein
Sfum_0535	ENOG4105EHZ	conserved protein UCP016719
Sfum_0536	ENOG4105C3F	Signal peptidase i
Sfum_0543	ENOG4105EJ5	oxidoreductase gamma subunit
Sfum_0545	ENOG4105WPN	DNA integration recombination invertion protein
Sfum_0546	ENOG4105DFU	Cell wall formation (By similarity)
Sfum_0548	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Sfum_0549	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Sfum_0551	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Sfum_0556	ENOG4105E6M	Sulphatase-modifying factor protein
Sfum_0558	ENOG4105F8J	Adenylate Guanylate cyclase
Sfum_0559	ENOG4105F8J	Adenylate Guanylate cyclase
Sfum_0561	ENOG4105C75	arginyL-tRNA synthetase
Sfum_0562	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Sfum_0564	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Sfum_0565	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Sfum_0567	ENOG4105VEQ	Cold shock protein
Sfum_0570	ENOG4108JUA	Transcriptional regulator
Sfum_0573	ENOG4108YZA	Nitrogen regulatory protein pii
Sfum_0574	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Sfum_0581	ENOG4105BZU	Histidine kinase
Sfum_0582	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Sfum_0583	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Sfum_0588	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
Sfum_0589	ENOG4108IJ0	Aspartate ammonia-lyase
Sfum_0593	ENOG4105IPI	Membrane
Sfum_0595	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Sfum_0596	ENOG41089BK	Glutamine amido-transferase
Sfum_0598	ENOG4105C3F	Signal peptidase i
Sfum_0599	ENOG4105EMN	RNA polymerase sigma factor
Sfum_0601	ENOG4108ZJ4	polysaccharide deacetylase
Sfum_0605	ENOG4108IYU	L-aspartate oxidase
Sfum_0608	ENOG4105EU4	polysulphide reductase NrfD
Sfum_0609	ENOG4107SFQ	iron-sulfur binding
Sfum_0610	ENOG4107UQT	molybdopterin oxidoreductase
Sfum_0615	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
Sfum_0617	ENOG4105BZU	Histidine kinase
Sfum_0618	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0619	ENOG4105BZU	Histidine kinase
Sfum_0620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0621	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0622	ENOG4105BZU	Histidine kinase
Sfum_0624	ENOG4107YZX	Universal stress protein
Sfum_0626	ENOG4105HF0	Membrane
Sfum_0630	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Sfum_0632	ENOG4105ETX	regulatoR
Sfum_0633	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0636	ENOG4105ETX	regulatoR
Sfum_0638	ENOG4108VCT	Sulfite exporter TauE/SafE
Sfum_0640	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Sfum_0642	ENOG4105BZU	Histidine kinase
Sfum_0643	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0648	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0649	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Sfum_0652	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Sfum_0654	ENOG410812K	response regulator receiver protein
Sfum_0656	ENOG4108UYB	regulatoR
Sfum_0657	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Sfum_0659	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Sfum_0660	ENOG4105C83	adenylosuccinate lyase
Sfum_0664	ENOG4105CFP	Peptidase U32
Sfum_0665	ENOG4107R7Y	intracellular protease Pfpi family
Sfum_0666	ENOG4105HAC	ABC-2 type transporter
Sfum_0674	ENOG4107S1E	Beta-lactamase
Sfum_0676	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Sfum_0679	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Sfum_0681	ENOG4108Z4T	Peptidase M50
Sfum_0682	ENOG4105C31	Tryptophanyl-tRNA synthetase
Sfum_0683	ENOG4105FE9	pseudouridine synthase
Sfum_0685	ENOG4105D9P	serine threonine protein kinase
Sfum_0688	ENOG4105CPI	Metal Dependent Phosphohydrolase
Sfum_0689	ENOG41082X2	rubredoxin
Sfum_0691	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Sfum_0692	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Sfum_0693	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Sfum_0695	ENOG4105CRE	cytochrome C
Sfum_0696	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Sfum_0698	ENOG4105C3M	thioredoxin reductase
Sfum_0700	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Sfum_0701	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Sfum_0702	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Sfum_0703	ENOG4105E2Z	phosphate ABC transporter (Permease
Sfum_0704	ENOG4105C8U	phosphate abc transporter
Sfum_0705	ENOG4105CVA	phosphate
Sfum_0706	ENOG4105BZU	Histidine kinase
Sfum_0707	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Sfum_0708	ENOG4105CD5	CoA-binding domain protein
Sfum_0712	ENOG4105CPF	Cell wall formation (By similarity)
Sfum_0713	ENOG4105CPF	Cell wall formation (By similarity)
Sfum_0715	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Sfum_0716	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Sfum_0718	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Sfum_0719	ENOG4105BZU	Histidine kinase
Sfum_0721	ENOG4105CYW	agmatinase
Sfum_0722	ENOG4108JU5	Magnesium and cobalt efflux protein
Sfum_0723	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Sfum_0724	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Sfum_0725	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Sfum_0726	ENOG4108YZA	Nitrogen regulatory protein pii
Sfum_0727	ENOG4105BZU	Histidine kinase
Sfum_0729	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Sfum_0730	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Sfum_0731	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Sfum_0735	ENOG4105BZU	Histidine kinase
Sfum_0736	ENOG4105C7B	Threonine dehydratase
Sfum_0738	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Sfum_0739	ENOG4105CD8	aminopeptidase N
Sfum_0741	ENOG4105CGH	5'-nucleotidase
Sfum_0745	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Sfum_0746	ENOG4105CYC	Transferase
Sfum_0748	ENOG4105E4C	Lytic transglycosylase catalytic
Sfum_0750	ENOG4107X35	defense response to bacterium
Sfum_0751	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Sfum_0752	ENOG4105E02	MotA TolQ exbB proton channel
Sfum_0753	ENOG4105M8F	Biopolymer transport protein exbD tolR
Sfum_0755	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Sfum_0756	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Sfum_0758	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sfum_0766	ENOG4107QHF	type ii secretion system protein e
Sfum_0767	ENOG4105DIN	metallophosphoesterase
Sfum_0769	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Sfum_0771	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Sfum_0773	ENOG4105KZ7	phosphocarrier protein hpr
Sfum_0774	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
Sfum_0781	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Sfum_0793	ENOG4105D3Q	Sugar transferase
Sfum_0794	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Sfum_0801	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Sfum_0803	ENOG4105CMR	udp-glucose 4-epimerase
Sfum_0805	ENOG4108ZCF	integral membrane protein
Sfum_0807	ENOG4107MM9	BNR Asp-box repeat-containing protein
Sfum_0809	ENOG4107UHT	Glutaconate CoA-transferase
Sfum_0813	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Sfum_0814	ENOG4107R0W	ABC transporter
Sfum_0815	ENOG4105EAD	ABC transporter
Sfum_0819	ENOG41086B8	CoB-CoM heterodisulfide reductase
Sfum_0821	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0827	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0833	ENOG4105C26	Dehydrogenase
Sfum_0835	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_0836	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Sfum_0837	ENOG4105C0Z	ABC transporter
Sfum_0838	ENOG4108IV0	ABC, transporter
Sfum_0841	ENOG4107QW8	radical SAM domain protein
Sfum_0844	ENOG4107QHI	-hydrogenase
Sfum_0845	ENOG4107QIZ	NADH dehydrogenase
Sfum_0846	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Sfum_0847	ENOG4105RWC	Hydrogenase, small subunit
Sfum_0848	ENOG4107QHI	-hydrogenase
Sfum_0852	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Sfum_0853	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0854	ENOG4105BZU	Histidine kinase
Sfum_0855	ENOG4105D1H	recombination factor protein RarA
Sfum_0856	ENOG4108IV0	ABC, transporter
Sfum_0857	ENOG4105C0Z	ABC transporter
Sfum_0858	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Sfum_0861	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_0868	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Sfum_0870	ENOG4105CEY	Amp-dependent synthetase and ligase
Sfum_0872	ENOG4105CD2	stage iii sporulation protein aa
Sfum_0874	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Sfum_0876	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Sfum_0877	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Sfum_0892	ENOG4105KVH	Transcriptional regulator
Sfum_0896	ENOG4107V2S	Transcriptional regulator
Sfum_0901	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
Sfum_0909	ENOG4105EPH	radical SAM domain protein
Sfum_0910	ENOG4108IGT	Dipeptidase
Sfum_0911	ENOG4107EPV	Aminotransferase class V
Sfum_0912	ENOG4105HFZ	Membrane
Sfum_0915	ENOG4105K7W	phage-related replication protein
Sfum_0918	ENOG4107XM9	(LipO)protein
Sfum_0926	ENOG4108IPJ	Membrane
Sfum_0927	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Sfum_0928	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Sfum_0929	ENOG4105C0B	DNA polymerase III (alpha subunit)
Sfum_0933	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Sfum_0934	ENOG4108YZG	isomerase
Sfum_0935	ENOG4105W87	Cbs domain
Sfum_0938	ENOG4105ERH	Fumarylacetoacetate hydrolase
Sfum_0942	ENOG4105BZU	Histidine kinase
Sfum_0943	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Sfum_0944	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Sfum_0948	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_0957	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Sfum_0958	ENOG4105CPF	Cell wall formation (By similarity)
Sfum_0959	ENOG4105PSV	Polysaccharide Biosynthesis Protein
Sfum_0962	ENOG4107QRS	glycosyltransferase group 2 family protein
Sfum_0967	ENOG4107QJZ	Glycosyl transferase, family 2
Sfum_0969	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
Sfum_0972	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Sfum_0975	ENOG4105D3Q	Sugar transferase
Sfum_0984	ENOG4105C0H	protease
Sfum_0986	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
Sfum_0993	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Sfum_0994	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Sfum_0995	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Sfum_0996	ENOG4105CDY	transcriptional regulatory protein
Sfum_0997	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Sfum_0998	ENOG4108UVJ	appr-1-p processing domain protein
Sfum_1003	ENOG4107QY8	reductase
Sfum_1004	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_1005	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_1009	ENOG4107SDT	Homocitrate synthase
Sfum_1010	ENOG4108JUA	Transcriptional regulator
Sfum_1011	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Sfum_1019	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
Sfum_1020	ENOG4105BZU	Histidine kinase
Sfum_1024	ENOG4105CHW	UPF0052 protein
Sfum_1025	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
Sfum_1033	ENOG4105CJR	Integral membrane protein (MviN
Sfum_1034	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Sfum_1035	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Sfum_1036	ENOG4105CFG	Acts as a chaperone (By similarity)
Sfum_1039	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Sfum_1040	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Sfum_1044	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Sfum_1046	ENOG4107RIQ	Sulfate adenylate transferase
Sfum_1049	ENOG4105EWK	phytoene
Sfum_1051	ENOG4105DF6	Fe-S oxidoreductase
Sfum_1058	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Sfum_1061	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Sfum_1064	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Sfum_1073	ENOG4105DPH	UPF0371 protein
Sfum_1074	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Sfum_1077	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Sfum_1079	ENOG4108PU5	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sfum_1080	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Sfum_1082	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_1083	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_1084	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Sfum_1086	ENOG4108IG5	Transcriptional regulator
Sfum_1087	ENOG4105C26	Dehydrogenase
Sfum_1093	ENOG4105EDV	vault protein
Sfum_1095	ENOG4107S52	alpha-2-macroglobulin domain protein
Sfum_1097	ENOG4108UPT	UPF0178 protein
Sfum_1101	ENOG4107PPM	cobalt chelatase
Sfum_1103	ENOG4108JJB	ABC transporter
Sfum_1105	ENOG4107BJW	polysaccharide deacetylase
Sfum_1106	ENOG4105CPK	Glycosyl transferase (Group 1
Sfum_1111	ENOG4108KU3	Integrase
Sfum_1120	ENOG4105BZU	Histidine kinase
Sfum_1121	ENOG4105CEY	Amp-dependent synthetase and ligase
Sfum_1131	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Sfum_1132	ENOG4107UHT	Glutaconate CoA-transferase
Sfum_1134	ENOG4105DMN	coenzyme A transferase
Sfum_1140	ENOG4108UYE	Lactoylglutathione lyase
Sfum_1144	ENOG4105E6M	Sulphatase-modifying factor protein
Sfum_1149	ENOG4107SFQ	iron-sulfur binding
Sfum_1151	ENOG4107QKZ	Ompa motb domain protein
Sfum_1152	ENOG4108JEZ	rRNA small subunit methyltransferase G
Sfum_1153	ENOG4108YBP	pseudouridine synthase
Sfum_1155	ENOG4105KT7	mgtC SapB transporter
Sfum_1163	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
Sfum_1164	ENOG4108JUB	Transcriptional regulator
Sfum_1166	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Sfum_1167	ENOG4105DQU	oxidoreductase, subunit beta
Sfum_1169	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Sfum_1171	ENOG4105CHM	Aminotransferase
Sfum_1172	ENOG4105EWK	phytoene
Sfum_1177	ENOG4105CAY	ferredoxin--nadp reductase
Sfum_1185	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Sfum_1187	ENOG4105KWI	UPF0339 protein
Sfum_1198	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Sfum_1201	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Sfum_1202	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Sfum_1204	ENOG4105C9B	Cysteine desulfurase
Sfum_1205	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Sfum_1208	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Sfum_1210	ENOG4105EGD	dinuclear metal center protein, YbgI family
Sfum_1212	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Sfum_1213	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Sfum_1214	ENOG4105KTH	gatB Yqey
Sfum_1215	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Sfum_1217	ENOG4105E3H	phosphoglycerate mutase
Sfum_1218	ENOG4105D6E	homoserine dehydrogenase
Sfum_1219	ENOG4105CHM	Aminotransferase
Sfum_1220	ENOG4105EM7	Selenocysteine-specific translation elongation factor
Sfum_1223	ENOG4107QX3	carboxylase
Sfum_1225	ENOG4105C0B	DNA polymerase III (alpha subunit)
Sfum_1226	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Sfum_1227	ENOG4105CHV	Transcription elongation factor NusA
Sfum_1228	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Sfum_1230	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Sfum_1231	ENOG4105SFS	phosphoesterase RecJ domain protein
Sfum_1232	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Sfum_1233	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Sfum_1234	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Sfum_1235	ENOG4105C1V	Peptidase, M16
Sfum_1236	ENOG4105Q2H	domain protein
Sfum_1238	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Sfum_1239	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Sfum_1246	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
Sfum_1247	ENOG4108R1E	Serine threonine protein phosphatase 1
Sfum_1254	ENOG4105CGD	Nad-dependent epimerase dehydratase
Sfum_1257	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Sfum_1260	ENOG4105C1G	acyl-Coa dehydrogenase
Sfum_1263	ENOG4105C8V	SAICAR synthetase
Sfum_1265	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Sfum_1267	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Sfum_1268	ENOG4105VN1	Heat shock protein
Sfum_1269	ENOG4105D0M	Protease HtpX homolog
Sfum_1271	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Sfum_1278	ENOG4105CYC	Transferase
Sfum_1281	ENOG4107QMS	site-determining protein
Sfum_1282	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Sfum_1283	ENOG4105C0B	DNA polymerase III (alpha subunit)
Sfum_1286	ENOG4105EWK	phytoene
Sfum_1287	ENOG4105EWK	phytoene
Sfum_1289	ENOG4105K4P	CoA-binding domain protein
Sfum_1293	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Sfum_1298	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Sfum_1299	ENOG4105NBF	ammecr1 domain protein
Sfum_1302	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Sfum_1303	ENOG4105D1F	ATP-binding protein
Sfum_1305	ENOG4105DZ1	carboxypeptidase
Sfum_1307	ENOG4107VAM	peptidase, m28
Sfum_1315	ENOG4105DZS	Phenylacetate-CoA ligase
Sfum_1316	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Sfum_1317	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Sfum_1318	ENOG4107QY8	reductase
Sfum_1327	ENOG4105EMN	RNA polymerase sigma factor
Sfum_1328	ENOG4105CPC	Aldo Keto reductase
Sfum_1329	ENOG4105HEE	Binding Domain protein
Sfum_1332	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Sfum_1333	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Sfum_1338	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Sfum_1339	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Sfum_1340	ENOG410846T	CoA-transferase family III
Sfum_1345	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
Sfum_1356	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Sfum_1361	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Sfum_1366	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Sfum_1369	ENOG41082GS	50S ribosomal protein L32
Sfum_1370	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Sfum_1372	ENOG4105BZJ	Electron transfer flavoprotein
Sfum_1373	ENOG4105C10	Electron transfer flavoprotein
Sfum_1374	ENOG4105CHR	reductase
Sfum_1375	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Sfum_1376	ENOG4108YZG	isomerase
Sfum_1377	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Sfum_1380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Sfum_1381	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Sfum_1382	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Sfum_1384	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Sfum_1388	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
Sfum_1390	ENOG4105BZ1	(ABC) transporter
Sfum_1391	ENOG4105BZ1	(ABC) transporter
Sfum_1393	ENOG4107TK4	histidinol-phosphate phosphatase
Sfum_1395	ENOG4108UKI	Enoyl-CoA hydratase
Sfum_1398	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Sfum_1400	ENOG4105CY0	Metallo-Beta-Lactamase
Sfum_1401	ENOG4107Z3H	Transcriptional regulator, TetR family
Sfum_1402	ENOG4105CSU	acyl-Coa dehydrogenase
Sfum_1403	ENOG4105CHU	acetyl-coa acetyltransferase
Sfum_1404	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Sfum_1411	ENOG4105DEF	Extracellular solute-binding protein, family 5
Sfum_1414	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Sfum_1415	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Sfum_1416	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Sfum_1418	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Sfum_1419	ENOG4105DX0	Hemolysin A
Sfum_1420	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Sfum_1421	ENOG41083MR	nifu domain-containing protein
Sfum_1422	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Sfum_1424	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Sfum_1425	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Sfum_1427	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Sfum_1428	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Sfum_1430	ENOG4105K70	DNA-binding protein
Sfum_1434	ENOG4105C25	Primosomal protein n'
Sfum_1436	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Sfum_1438	ENOG4105K59	histidine triad (HIT) protein
Sfum_1445	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
Sfum_1452	ENOG4105C1J	atp-dependent rna helicase
Sfum_1462	ENOG4108NST	exported protein
Sfum_1469	ENOG4107RCW	fructose-bisphosphate aldolase
Sfum_1472	ENOG4105C6K	Malic enzyme
Sfum_1473	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Sfum_1476	ENOG4105D0C	transport protein
Sfum_1477	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Sfum_1479	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Sfum_1487	ENOG4105BZU	Histidine kinase
Sfum_1488	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_1504	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Sfum_1506	ENOG41083UI	stage II sporulation protein
Sfum_1513	ENOG4105EYW	Ion transport protein
Sfum_1514	ENOG410630Q	Methylamine utilization
Sfum_1521	ENOG4105EJ9	Membrane
Sfum_1522	ENOG4105JXH	GntR family transcriptional regulator
Sfum_1525	ENOG4108YXV	Transcriptional regulator
Sfum_1527	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Sfum_1529	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
Sfum_1531	ENOG4105RK9	auxin efflux carrier
Sfum_1533	ENOG4105BZN	citrate synthase
Sfum_1541	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Sfum_1542	ENOG41084ED	50S ribosomal protein L33
Sfum_1544	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Sfum_1545	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Sfum_1546	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Sfum_1547	ENOG4108VZM	50s ribosomal protein L10
Sfum_1548	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Sfum_1549	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Sfum_1550	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Sfum_1551	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Sfum_1552	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Sfum_1553	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Sfum_1554	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Sfum_1555	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Sfum_1556	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Sfum_1557	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Sfum_1558	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Sfum_1559	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Sfum_1560	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Sfum_1561	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Sfum_1562	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Sfum_1563	ENOG41082SA	50s ribosomal protein l29
Sfum_1564	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Sfum_1565	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Sfum_1566	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Sfum_1567	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Sfum_1568	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Sfum_1569	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Sfum_1570	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Sfum_1571	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Sfum_1572	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Sfum_1573	ENOG4105VPB	50S ribosomal protein L30
Sfum_1574	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Sfum_1575	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Sfum_1576	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Sfum_1578	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Sfum_1579	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Sfum_1580	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Sfum_1581	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Sfum_1582	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Sfum_1583	ENOG4108ZT0	50S ribosomal protein l17
Sfum_1585	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Sfum_1586	ENOG4105EAH	synthase
Sfum_1588	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Sfum_1589	ENOG4105CRE	cytochrome C
Sfum_1590	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Sfum_1592	ENOG410888F	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Sfum_1595	ENOG4108UUM	single-stranded DNA-binding protein
Sfum_1597	ENOG4105CN5	Metallo-Beta-Lactamase
Sfum_1598	ENOG4105CNU	cell division protein FtsK
Sfum_1600	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Sfum_1601	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Sfum_1602	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Sfum_1603	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Sfum_1604	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Sfum_1605	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
Sfum_1608	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Sfum_1609	ENOG4105C03	ribonuclease
Sfum_1610	ENOG4105EPH	radical SAM domain protein
Sfum_1612	ENOG4105C2M	dna polymerase I
Sfum_1613	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Sfum_1627	ENOG4105D8X	mechanosensitive ion channel
Sfum_1632	ENOG4105EGS	Mechanosensitive ion channel
Sfum_1634	ENOG4105C8N	cysteinyl-tRNA synthetase
Sfum_1636	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Sfum_1637	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Sfum_1639	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Sfum_1645	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Sfum_1647	ENOG4108V3W	Chemotaxis protein, CheW
Sfum_1648	ENOG4105C8Q	Methyl-accepting chemotaxis
Sfum_1650	ENOG4105CBS	Chea signal transduction histidine kinase
Sfum_1650	ENOG4105CBS	Chea signal transduction histidine kinase
Sfum_1651	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Sfum_1652	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Sfum_1654	ENOG4105CXV	gliding motility protein
Sfum_1656	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Sfum_1657	ENOG4105D7N	magnesium and cobalt transport protein CorA
Sfum_1663	ENOG4108VYJ	response regulator receiver protein
Sfum_1664	ENOG4105WH1	Two component transcriptional regulator luxr family
Sfum_1666	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Sfum_1667	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Sfum_1668	ENOG4108UJD	30S ribosomal protein S9
Sfum_1669	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Sfum_1675	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Sfum_1676	ENOG4105DZS	Phenylacetate-CoA ligase
Sfum_1677	ENOG4108IV0	ABC, transporter
Sfum_1678	ENOG4105C0Z	ABC transporter
Sfum_1679	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Sfum_1680	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_1683	ENOG4105DZS	Phenylacetate-CoA ligase
Sfum_1685	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Sfum_1691	ENOG4105D78	K07001 NTE family protein
Sfum_1692	ENOG4105DWF	phosphomethylpyrimidine kinase
Sfum_1693	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Sfum_1694	ENOG4105CZX	twitching motility protein
Sfum_1695	ENOG4105CZX	twitching motility protein
Sfum_1698	ENOG4108I5C	dEAD DEAH box helicase
Sfum_1700	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Sfum_1701	ENOG4105F4R	Transcriptional regulator mode
Sfum_1702	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Sfum_1703	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Sfum_1705	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Sfum_1706	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Sfum_1707	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Sfum_1708	ENOG4105K63	Thioredoxin
Sfum_1711	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Sfum_1712	ENOG41082DI	50s ribosomal protein l31
Sfum_1713	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Sfum_1714	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Sfum_1715	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Sfum_1716	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Sfum_1721	ENOG4105CH6	catalase
Sfum_1723	ENOG4105BZ8	glutamate synthase
Sfum_1724	ENOG4105CBC	glutamate synthase
Sfum_1728	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Sfum_1731	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
Sfum_1732	ENOG4105C5X	domain protein
Sfum_1736	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Sfum_1737	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Sfum_1738	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Sfum_1739	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Sfum_1740	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Sfum_1741	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Sfum_1742	ENOG4105VN1	Heat shock protein
Sfum_1743	ENOG4105MYT	Heat shock protein
Sfum_1749	ENOG4107ZYJ	bioY protein
Sfum_1750	ENOG4108JJB	ABC transporter
Sfum_1751	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Sfum_1756	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Sfum_1758	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Sfum_1762	ENOG4108FN7	Aldo keto reductase
Sfum_1767	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Sfum_1770	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Sfum_1771	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Sfum_1772	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Sfum_1773	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Sfum_1774	ENOG4107QYG	anthranilate phosphoribosyltransferase
Sfum_1775	ENOG4105DDQ	anthranilate synthase
Sfum_1776	ENOG4105CRQ	synthase (Component I)
Sfum_1777	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Sfum_1778	ENOG4105CE9	30S ribosomal protein S2
Sfum_1779	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Sfum_1780	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Sfum_1781	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Sfum_1782	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Sfum_1783	ENOG4105KNE	Phosphatidate cytidylyltransferase
Sfum_1784	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Sfum_1785	ENOG4105DZP	Membrane-associated zinc metalloprotease
Sfum_1786	ENOG41072GX	Peptidase M22 Glycoprotease
Sfum_1791	ENOG4105DPX	Hydrogenase, large subunit
Sfum_1795	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Sfum_1796	ENOG4108JB9	formate dehydrogenase
Sfum_1800	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Sfum_1801	ENOG4105DF6	Fe-S oxidoreductase
Sfum_1808	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Sfum_1809	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Sfum_1812	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Sfum_1814	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Sfum_1815	ENOG4105E63	Pfam:DUF178
Sfum_1817	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Sfum_1818	ENOG41084UG	Pfam:DUF1458
Sfum_1821	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Sfum_1822	ENOG4105D41	biosynthesis protein thiH
Sfum_1823	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Sfum_1824	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Sfum_1825	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Sfum_1826	ENOG4105E3A	(ABC) transporter
Sfum_1831	ENOG4105C03	ribonuclease
Sfum_1835	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Sfum_1838	ENOG4105BZM	domain protein
Sfum_1841	ENOG4105D41	biosynthesis protein thiH
Sfum_1842	ENOG4108IJ0	Aspartate ammonia-lyase
Sfum_1843	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Sfum_1844	ENOG4107QW8	radical SAM domain protein
Sfum_1851	ENOG41060W2	glyoxylate carboligase
Sfum_1860	ENOG4105BZ1	(ABC) transporter
Sfum_1865	ENOG4105DR4	Methyltransferase
Sfum_1876	ENOG4105CF2	Mu-like prophage FluMu protein GP28
Sfum_1877	ENOG4105QIB	mu-like prophage Flumu protein gp29
Sfum_1882	ENOG4105EFV	Major head subunit
Sfum_1884	ENOG4105Y5J	prophage protein
Sfum_1905	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Sfum_1907	ENOG4107V2S	Transcriptional regulator
Sfum_1909	ENOG4105C7H	Helicase, RecD TraA family
Sfum_1911	ENOG4105N42	UPF0307 protein
Sfum_1913	ENOG4105DKQ	ROK family
Sfum_1915	ENOG4105W87	Cbs domain
Sfum_1917	ENOG4105DFF	Rod shape-determining protein mreb
Sfum_1919	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Sfum_1920	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Sfum_1923	ENOG4105EMU	Dehydrogenase
Sfum_1926	ENOG4105C34	Pseudouridine synthase
Sfum_1931	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Sfum_1933	ENOG4105ES5	Histidine kinase
Sfum_1934	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_1935	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_1936	ENOG4105C8S	subunit m
Sfum_1938	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_1939	ENOG4107UFS	subunit j
Sfum_1940	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_1941	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Sfum_1942	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_1943	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Sfum_1945	ENOG4105CNA	YD repeat protein
Sfum_1946	ENOG4105CNA	YD repeat protein
Sfum_1951	ENOG4105DJV	ribulose-phosphate 3-epimerase
Sfum_1952	ENOG4107QP8	phosphohexose isomerase
Sfum_1953	ENOG4105DKQ	ROK family
Sfum_1954	ENOG4107R0R	NADH dehydrogenase subunit g
Sfum_1956	ENOG4105GKE	subunit e
Sfum_1958	ENOG4105C5X	domain protein
Sfum_1961	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Sfum_1962	ENOG4105D07	Signal peptide peptidase, SppA
Sfum_1963	ENOG4107RP9	extracellular solute-binding protein, family 3
Sfum_1966	ENOG4105CD5	CoA-binding domain protein
Sfum_1967	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Sfum_1978	ENOG4105CTD	carboxy-peptidase
Sfum_1979	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
Sfum_1981	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
Sfum_1983	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Sfum_1984	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Sfum_1985	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Sfum_1988	ENOG4105U5Y	Transcriptional regulator
Sfum_1989	ENOG4105EWU	Squalene--hopene cyclase
Sfum_1994	ENOG4108E19	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Sfum_1996	ENOG4105NBF	ammecr1 domain protein
Sfum_1997	ENOG4106HNH	Acyl-transferase
Sfum_1998	ENOG4105E33	succinate dehydrogenase
Sfum_1999	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Sfum_2000	ENOG4108S24	Fumarate reduCtase
Sfum_2005	ENOG4105C0H	protease
Sfum_2006	ENOG4106F60	Histidine kinase
Sfum_2012	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Sfum_2015	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Sfum_2032	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Sfum_2034	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Sfum_2040	ENOG4105CGZ	zinc metallopeptidase
Sfum_2044	ENOG41068KG	domain protein
Sfum_2057	ENOG4107R3N	Filamentation induced by cAMP protein fic
Sfum_2059	ENOG4105CP7	Triose-phosphate isomerase
Sfum_2060	ENOG4105BZA	Phosphoglycerate kinase
Sfum_2062	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Sfum_2063	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Sfum_2066	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Sfum_2067	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Sfum_2069	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Sfum_2070	ENOG4108IUZ	ABC transporter
Sfum_2073	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Sfum_2074	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Sfum_2075	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Sfum_2076	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Sfum_2081	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Sfum_2082	ENOG4105D06	uba thif-type nad fad binding protein
Sfum_2083	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Sfum_2084	ENOG4105C8T	Leucyl-tRNA synthetase
Sfum_2087	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
Sfum_2089	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Sfum_2090	ENOG4105CXT	aspartate transcarbamylase
Sfum_2091	ENOG4105CD3	dihydroorotase
Sfum_2092	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2095	ENOG4105ECY	inositol monophosphatase
Sfum_2097	ENOG4105ID8	Transcriptional regulator, ARAC family
Sfum_2102	ENOG4105C9Q	fumarate hydratase class II
Sfum_2103	ENOG4105E33	succinate dehydrogenase
Sfum_2105	ENOG4105BZN	citrate synthase
Sfum_2106	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Sfum_2107	ENOG4105K70	DNA-binding protein
Sfum_2111	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Sfum_2112	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Sfum_2113	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Sfum_2115	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Sfum_2116	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Sfum_2117	ENOG4105CAT	Cytidine monophosphate kinase
Sfum_2118	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Sfum_2120	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Sfum_2121	ENOG4105D49	3-dehydroquinate synthase
Sfum_2122	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Sfum_2123	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Sfum_2129	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Sfum_2130	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
Sfum_2131	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Sfum_2133	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Sfum_2134	ENOG4105EHG	Permease protein
Sfum_2135	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Sfum_2136	ENOG41081F0	Precorrin-8x methylmutase
Sfum_2137	ENOG4105DJZ	UPF0182 protein
Sfum_2138	ENOG4105VTS	DnaJ-like, subfamily C
Sfum_2141	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_2143	ENOG4105C0Z	ABC transporter
Sfum_2144	ENOG4108IV0	ABC, transporter
Sfum_2146	ENOG4107QQM	Cysteine-rich domain
Sfum_2150	ENOG4105BZ8	glutamate synthase
Sfum_2151	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Sfum_2152	ENOG4107R0R	NADH dehydrogenase subunit g
Sfum_2156	ENOG4105CBG	Sulfatase
Sfum_2157	ENOG4105C4X	radical SAM domain protein
Sfum_2161	ENOG4105DXN	mazG family
Sfum_2163	ENOG4105C9A	Phoh family
Sfum_2164	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Sfum_2165	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Sfum_2166	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Sfum_2167	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Sfum_2168	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Sfum_2169	ENOG4105K8N	protein family UPF0079, ATPase
Sfum_2173	ENOG4105CFH	Aspartokinase
Sfum_2174	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Sfum_2177	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Sfum_2181	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Sfum_2183	ENOG4105D75	Capsular exopolysaccharide family
Sfum_2188	ENOG4108KMV	Glycosyl transferase (Group 1
Sfum_2190	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Sfum_2195	ENOG4105K4H	Nlp p60 protein
Sfum_2197	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Sfum_2202	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Sfum_2205	ENOG4107XKF	NMT1 THI5 Like Domain Protein
Sfum_2207	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Sfum_2208	ENOG4105BZU	Histidine kinase
Sfum_2209	ENOG4105BZU	Histidine kinase
Sfum_2210	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Sfum_2212	ENOG4105CVA	phosphate
Sfum_2213	ENOG4107RSS	Hydrogenase accessory protein HypB
Sfum_2214	ENOG4108JUB	Transcriptional regulator
Sfum_2222	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sfum_2226	ENOG4105BZ4	penicillin-binding protein
Sfum_2227	ENOG4105DN3	alpha-2-macroglobulin domain protein
Sfum_2233	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_2234	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_2235	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Sfum_2239	ENOG4105XA0	heptosyltransferase ii
Sfum_2243	ENOG4106WTF	Glycosyl transferase, family 2
Sfum_2248	ENOG4107STQ	Multicopper oxidase
Sfum_2251	ENOG4105DQ4	alcohol dehydrogenase
Sfum_2252	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Sfum_2261	ENOG4107TYR	Glycosyl Transferase
Sfum_2263	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Sfum_2265	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Sfum_2271	ENOG4105Q9Y	Universal stress protein
Sfum_2272	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Sfum_2275	ENOG4105CJ3	phosphate transporter
Sfum_2280	ENOG4105CHU	acetyl-coa acetyltransferase
Sfum_2281	ENOG4108IV0	ABC, transporter
Sfum_2282	ENOG4105C0Z	ABC transporter
Sfum_2283	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Sfum_2284	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_2287	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Sfum_2288	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Sfum_2290	ENOG4105D6N	CoA-transferase, subunit a
Sfum_2291	ENOG4107QNJ	CoA-transferase subunit B
Sfum_2292	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2294	ENOG4105BZU	Histidine kinase
Sfum_2301	ENOG4105VSH	4-oxalocrotonate tautomerase
Sfum_2304	ENOG4105BZU	Histidine kinase
Sfum_2307	ENOG4105BZU	Histidine kinase
Sfum_2312	ENOG4105ES4	Nitrilase
Sfum_2313	ENOG4108IV0	ABC, transporter
Sfum_2314	ENOG4105C0Z	ABC transporter
Sfum_2319	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Sfum_2320	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
Sfum_2323	ENOG4108NST	exported protein
Sfum_2324	ENOG4107G43	radical SAM domain protein
Sfum_2325	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Sfum_2326	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Sfum_2329	ENOG4108SA1	esterase
Sfum_2332	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Sfum_2333	ENOG4107QI1	Mate efflux family protein
Sfum_2336	ENOG4107GFK	fumarate
Sfum_2338	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Sfum_2340	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
Sfum_2345	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Sfum_2346	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Sfum_2348	ENOG41088YS	Glycosyl transferase (Group 1
Sfum_2352	ENOG4105CMQ	Chloride channel
Sfum_2364	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Sfum_2366	ENOG4105VN1	Heat shock protein
Sfum_2367	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Sfum_2372	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Sfum_2375	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Sfum_2376	ENOG4105CGP	Urocanate hydratase
Sfum_2377	ENOG4105CI2	imidazolone-5-propionate hydrolase
Sfum_2378	ENOG4105C84	Histidine ammonia-lyase
Sfum_2380	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Sfum_2381	ENOG4108K0D	peptidase, M48
Sfum_2382	ENOG4108T5G	Adenylate
Sfum_2387	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Sfum_2391	ENOG4105CJ1	ABC, transporter
Sfum_2392	ENOG4107QWP	ABC-2 type transporter
Sfum_2393	ENOG4107QWP	ABC-2 type transporter
Sfum_2395	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Sfum_2396	ENOG4105CJW	magnesium transporter
Sfum_2398	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
Sfum_2400	ENOG41076HS	cation diffusion facilitator family transporter
Sfum_2404	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Sfum_2409	ENOG4105C3M	thioredoxin reductase
Sfum_2410	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Sfum_2412	ENOG4105C0H	protease
Sfum_2414	ENOG4105CY3	ABC transporter, permease
Sfum_2416	ENOG4105DY2	Paraquat-inducible protein b
Sfum_2428	ENOG4105EXU	Membrane
Sfum_2430	ENOG4107ZBH	radical SAM domain protein
Sfum_2433	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Sfum_2438	ENOG4108IJ0	Aspartate ammonia-lyase
Sfum_2439	ENOG4105NXH	GreA GreB family elongation factor
Sfum_2442	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2445	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Sfum_2446	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Sfum_2449	ENOG4105DHJ	ABC, transporter
Sfum_2450	ENOG4105CY3	ABC transporter, permease
Sfum_2452	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
Sfum_2453	ENOG4108MJI	response regulator
Sfum_2456	ENOG4105C4X	radical SAM domain protein
Sfum_2460	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Sfum_2461	ENOG4105D2N	Aldolase
Sfum_2463	ENOG4105CPQ	Dehydrogenase
Sfum_2464	ENOG41061GT	Aldolase
Sfum_2466	ENOG4105CD5	CoA-binding domain protein
Sfum_2468	ENOG4108RAC	Rubrerythrin
Sfum_2470	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Sfum_2473	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Sfum_2474	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Sfum_2475	ENOG4105C5S	asparaginyl-tRNA synthetase
Sfum_2480	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Sfum_2493	ENOG4105CE1	Ferrous iron transport protein b
Sfum_2494	ENOG4105D49	3-dehydroquinate synthase
Sfum_2495	ENOG4105BZU	Histidine kinase
Sfum_2498	ENOG4107R34	abc transporter permease protein
Sfum_2499	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Sfum_2507	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_2509	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
Sfum_2510	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Sfum_2512	ENOG4108V4B	ThiJ pfpI
Sfum_2516	ENOG4105C2J	ABC transporter
Sfum_2517	ENOG4105UIB	(ABC) transporter
Sfum_2521	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Sfum_2523	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Sfum_2524	ENOG4105DIN	metallophosphoesterase
Sfum_2525	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Sfum_2526	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sfum_2527	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Sfum_2528	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Sfum_2530	ENOG4107TH8	cina domain protein
Sfum_2531	ENOG4105C8M	UPF0272 protein
Sfum_2534	ENOG4106H3A	restriction
Sfum_2537	ENOG4105D9P	serine threonine protein kinase
Sfum_2541	ENOG4105Q36	FHA domain containing protein
Sfum_2542	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
Sfum_2547	ENOG4105C7Z	Conserved Protein
Sfum_2548	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
Sfum_2553	ENOG4108WWZ	General secretion pathway protein J
Sfum_2558	ENOG4106855	Competence protein
Sfum_2560	ENOG4105BZU	Histidine kinase
Sfum_2561	ENOG4105CI0	Citrate lyase
Sfum_2562	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Sfum_2563	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
Sfum_2564	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
Sfum_2565	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
Sfum_2566	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
Sfum_2567	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
Sfum_2570	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Sfum_2571	ENOG4105E0X	reductase
Sfum_2572	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Sfum_2577	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Sfum_2578	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Sfum_2580	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Sfum_2581	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Sfum_2582	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Sfum_2583	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Sfum_2584	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Sfum_2585	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Sfum_2586	ENOG410835G	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Sfum_2588	ENOG4105CNI	cell division protein FtsW
Sfum_2592	ENOG4105DFF	Rod shape-determining protein mreb
Sfum_2594	ENOG41084CH	50S ribosomal protein l34
Sfum_2595	ENOG41084AH	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Sfum_2596	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Sfum_2597	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Sfum_2598	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
Sfum_2599	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Sfum_2601	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Sfum_2603	ENOG4105WQI	isochorismatase
Sfum_2605	ENOG4107QJE	Chromosome Partitioning Protein
Sfum_2606	ENOG4105FA0	parb-like partition protein
Sfum_2609	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Sfum_2611	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Sfum_2612	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Sfum_2613	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Sfum_2616	ENOG4105BZ1	(ABC) transporter
Sfum_2617	ENOG4105C08	Histidine kinase
Sfum_2618	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Sfum_2620	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Sfum_2621	ENOG4105ES5	Histidine kinase
Sfum_2622	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2630	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Sfum_2632	ENOG41062T2	Acyl carrier protein
Sfum_2637	ENOG4105C0P	Mg chelatase subunit ChlI
Sfum_2642	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Sfum_2643	ENOG4105C1J	atp-dependent rna helicase
Sfum_2644	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Sfum_2645	ENOG4107QN2	dihydrolipoyl dehydrogenase
Sfum_2646	ENOG4107QSN	dihydrolipoamide acetyltransferase
Sfum_2647	ENOG4105CPP	Dehydrogenase, E1 component
Sfum_2648	ENOG4107RUY	(E1 component), alpha subunit
Sfum_2649	ENOG4108JPW	Aminotransferase
Sfum_2650	ENOG4105BZU	Histidine kinase
Sfum_2654	ENOG4105CT7	inner membrane cred family protein
Sfum_2656	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Sfum_2657	ENOG4105EB3	Histidine kinase
Sfum_2666	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Sfum_2669	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Sfum_2670	ENOG4105C28	cystathionine
Sfum_2671	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Sfum_2675	ENOG4105BZU	Histidine kinase
Sfum_2677	ENOG4105DVT	helicase
Sfum_2682	ENOG4105D7W	serine acetyltransferase
Sfum_2683	ENOG4105C3J	Cysteine desulfurase
Sfum_2684	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Sfum_2686	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Sfum_2687	ENOG4105CKU	formyltetrahydrofolate synthetase
Sfum_2688	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Sfum_2689	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Sfum_2690	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Sfum_2691	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Sfum_2693	ENOG4105CJ2	(LipO)protein
Sfum_2694	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
Sfum_2695	ENOG4105DGN	Electron transport complex
Sfum_2696	ENOG4105DZB	Electron transport complex
Sfum_2697	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
Sfum_2698	ENOG4105D6A	Electron transport complex
Sfum_2699	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Sfum_2703	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Sfum_2704	ENOG4107QIZ	NADH dehydrogenase
Sfum_2705	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Sfum_2706	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Sfum_2707	ENOG4105TMB	Formate nitrite transporter
Sfum_2710	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Sfum_2712	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Sfum_2713	ENOG4107QIZ	NADH dehydrogenase
Sfum_2720	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Sfum_2721	ENOG4105E2X	shikimate dehydrogenase
Sfum_2722	ENOG4105FF2	Type I DHQase
Sfum_2723	ENOG4105CQC	Prephenate dehydratase
Sfum_2724	ENOG4106M32	3-dehydroquinate synthase
Sfum_2727	ENOG4107QRP	cobalamin biosynthesis protein CobW
Sfum_2734	ENOG4105DIK	(ABC) transporter
Sfum_2736	ENOG4105EWU	Squalene--hopene cyclase
Sfum_2737	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Sfum_2739	ENOG4105E0A	ABC, transporter
Sfum_2740	ENOG4105EHG	Permease protein
Sfum_2741	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Sfum_2744	ENOG4105D05	Receptor
Sfum_2745	ENOG4107PPM	cobalt chelatase
Sfum_2748	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
Sfum_2753	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Sfum_2756	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Sfum_2757	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Sfum_2758	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Sfum_2759	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Sfum_2760	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Sfum_2761	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Sfum_2763	ENOG4105BZU	Histidine kinase
Sfum_2764	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2766	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Sfum_2768	ENOG4105D7N	magnesium and cobalt transport protein CorA
Sfum_2772	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2777	ENOG4105C6K	Malic enzyme
Sfum_2784	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Sfum_2788	ENOG4108Z6B	deaminase
Sfum_2789	ENOG4105C6E	dna polymerase iii
Sfum_2790	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Sfum_2791	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Sfum_2792	ENOG4105EJ5	oxidoreductase gamma subunit
Sfum_2794	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Sfum_2795	ENOG4105DDK	oxidoreductase, beta subunit
Sfum_2802	ENOG4108T5G	Adenylate
Sfum_2805	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Sfum_2806	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2807	ENOG4105BZU	Histidine kinase
Sfum_2808	ENOG4107QI6	Cysteine desulfurase
Sfum_2810	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_2817	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Sfum_2819	ENOG4105VYW	UPF0251 protein
Sfum_2822	ENOG4105EYH	Exonuclease
Sfum_2827	ENOG41060M0	Crispr-associated protein, cse4 family
Sfum_2830	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Sfum_2831	ENOG4105PWE	CRISPR-associated protein cas2
Sfum_2834	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Sfum_2845	ENOG4107XM9	(LipO)protein
Sfum_2848	ENOG4105K59	histidine triad (HIT) protein
Sfum_2850	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Sfum_2851	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Sfum_2852	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Sfum_2856	ENOG4107QMH	DNA methylase
Sfum_2859	ENOG4105ENA	helicase
Sfum_2860	ENOG4105VN1	Heat shock protein
Sfum_2864	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Sfum_2866	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2868	ENOG4105CI3	gtp-binding protein typa
Sfum_2875	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
Sfum_2876	ENOG4108M26	parallel beta-helix repeat protein
Sfum_2880	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Sfum_2881	ENOG4105N1F	Hnh endonuclease
Sfum_2884	ENOG4105MHT	Transcriptional regulator, ARSR family
Sfum_2885	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Sfum_2886	ENOG4105CVA	phosphate
Sfum_2887	ENOG4105C8U	phosphate abc transporter
Sfum_2888	ENOG4105E2Z	phosphate ABC transporter (Permease
Sfum_2889	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Sfum_2890	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Sfum_2891	ENOG4105BZU	Histidine kinase
Sfum_2892	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Sfum_2894	ENOG4108Z5K	methylglyoxal synthase
Sfum_2895	ENOG4107STF	Involved in phosphonate degradation (By similarity)
Sfum_2896	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
Sfum_2897	ENOG4107RCV	ABC transporter, permease
Sfum_2902	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Sfum_2903	ENOG4105BZF	Glycosyl transferase (Group 1
Sfum_2904	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Sfum_2906	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Sfum_2908	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Sfum_2912	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Sfum_2913	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Sfum_2921	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Sfum_2925	ENOG4105C8Y	Acetylornithine aminotransferase
Sfum_2928	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
Sfum_2932	ENOG4105DSQ	Nitric oxide reductase
Sfum_2933	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
Sfum_2935	ENOG4105VCQ	rubredoxin
Sfum_2941	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Sfum_2943	ENOG4105CQZ	Histidine kinase
Sfum_2944	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Sfum_2945	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Sfum_2946	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Sfum_2948	ENOG4105CAG	UPF0210 protein
Sfum_2950	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
Sfum_2952	ENOG4105DPX	Hydrogenase, large subunit
Sfum_2953	ENOG4105E3S	small subunit
Sfum_2954	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Sfum_2955	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_2958	ENOG4105CTQ	phosphohexokinase
Sfum_2960	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Sfum_2961	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Sfum_2963	ENOG4105CQ7	ATP-dependent helicase
Sfum_2968	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Sfum_2969	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Sfum_2974	ENOG4105F2Z	3-oxoadipate enol-lactonase
Sfum_2975	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Sfum_2981	ENOG4105C7K	acetolactate synthase
Sfum_2982	ENOG4105C7K	acetolactate synthase
Sfum_2983	ENOG4108ZP8	Acetolactate synthase small subunit
Sfum_2985	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Sfum_2986	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Sfum_2987	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Sfum_2988	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Sfum_2989	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Sfum_2990	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Sfum_2991	ENOG4106H78	methyltransferase
Sfum_2992	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Sfum_2993	ENOG4105CVE	Lytic murein transglycosylase
Sfum_2995	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Sfum_2997	ENOG4105K5M	30s ribosomal protein S16
Sfum_2998	ENOG4105VB6	UPF0109 protein
Sfum_2999	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Sfum_3000	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Sfum_3001	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
Sfum_3002	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Sfum_3003	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Sfum_3004	ENOG41082RQ	UPF0102 protein
Sfum_3008	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Sfum_3009	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Sfum_3010	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Sfum_3011	ENOG4107VAM	peptidase, m28
Sfum_3016	ENOG4105F2Z	3-oxoadipate enol-lactonase
Sfum_3017	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Sfum_3023	ENOG4105C7K	acetolactate synthase
Sfum_3024	ENOG4105C7K	acetolactate synthase
Sfum_3025	ENOG4108ZP8	Acetolactate synthase small subunit
Sfum_3027	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Sfum_3028	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Sfum_3029	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Sfum_3030	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Sfum_3031	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Sfum_3032	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Sfum_3033	ENOG4106H78	methyltransferase
Sfum_3034	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Sfum_3035	ENOG4105CVE	Lytic murein transglycosylase
Sfum_3037	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Sfum_3039	ENOG4105K5M	30s ribosomal protein S16
Sfum_3040	ENOG4105VB6	UPF0109 protein
Sfum_3041	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Sfum_3042	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Sfum_3043	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
Sfum_3044	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Sfum_3045	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Sfum_3046	ENOG41082RQ	UPF0102 protein
Sfum_3050	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Sfum_3051	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Sfum_3052	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Sfum_3053	ENOG4107VAM	peptidase, m28
Sfum_3054	ENOG4105KT7	mgtC SapB transporter
Sfum_3055	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Sfum_3056	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Sfum_3057	ENOG4105D52	delta-aminolevulinic acid dehydratase
Sfum_3058	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Sfum_3063	ENOG4105CN1	protease
Sfum_3066	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Sfum_3070	ENOG4105CYC	Transferase
Sfum_3071	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Sfum_3073	ENOG4105C26	Dehydrogenase
Sfum_3074	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Sfum_3075	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Sfum_3076	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Sfum_3077	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Sfum_3083	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Sfum_3084	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Sfum_3085	ENOG41061GT	Aldolase
Sfum_3088	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Sfum_3089	ENOG4105DVY	radical SAM domain protein
Sfum_3090	ENOG4108W9H	Tetr family transcriptional regulator
Sfum_3096	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Sfum_3097	ENOG4105E55	glycerol-3-phosphate acyltransferase
Sfum_3098	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Sfum_3101	ENOG4108IV0	ABC, transporter
Sfum_3102	ENOG4105C0Z	ABC transporter
Sfum_3103	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Sfum_3104	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_3106	ENOG4105DCF	alanine dehydrogenase
Sfum_3109	ENOG4105BZU	Histidine kinase
Sfum_3111	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_3114	ENOG4105CKK	Glycosyl transferase, family 2
Sfum_3133	ENOG4108JU3	Alkyl hydroperoxide reductase
Sfum_3136	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
Sfum_3138	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Sfum_3139	ENOG4105DQU	oxidoreductase, subunit beta
Sfum_3142	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Sfum_3145	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Sfum_3148	ENOG4105C6F	GntR Family Transcriptional Regulator
Sfum_3152	ENOG4107QNM	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
Sfum_3155	ENOG4105IIU	Aminopeptidase
Sfum_3159	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
Sfum_3160	ENOG4105CIZ	coA-substrate-specific enzyme activase
Sfum_3161	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
Sfum_3162	ENOG4105CNN	ABC, transporter
Sfum_3163	ENOG4107RP9	extracellular solute-binding protein, family 3
Sfum_3164	ENOG4105EAD	ABC transporter
Sfum_3165	ENOG4105DRP	amino acid AbC transporter
Sfum_3175	ENOG4105EYF	MMPL domain protein
Sfum_3182	ENOG4105DTN	riboflavin biosynthesis protein ribF
Sfum_3184	ENOG4105CDU	Replicative dna helicase
Sfum_3185	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Sfum_3187	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Sfum_3188	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Sfum_3191	ENOG4105VB6	UPF0109 protein
Sfum_3195	ENOG4108J2R	molybdopterin oxidoreductase
Sfum_3197	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Sfum_3200	ENOG4105EKQ	RNA-directed DNA polymerase
Sfum_3202	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Sfum_3206	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Sfum_3215	ENOG4105ECP	epimerase
Sfum_3217	ENOG410688J	Ferredoxin
Sfum_3218	ENOG4108JU3	Alkyl hydroperoxide reductase
Sfum_3219	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
Sfum_3222	ENOG4105VCQ	rubredoxin
Sfum_3231	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Sfum_3233	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Sfum_3234	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
Sfum_3236	ENOG4105DHT	Metal Dependent Phosphohydrolase
Sfum_3237	ENOG4105D9P	serine threonine protein kinase
Sfum_3244	ENOG4105D82	Glutamate dehydrogenase
Sfum_3246	ENOG4105KXX	peptidase s58 dmpa
Sfum_3250	ENOG4105BZ1	(ABC) transporter
Sfum_3252	ENOG4108RAC	Rubrerythrin
Sfum_3253	ENOG4105CNW	domain protein
Sfum_3256	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
Sfum_3263	ENOG4107QNM	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
Sfum_3265	ENOG4105D82	Glutamate dehydrogenase
Sfum_3268	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_3269	ENOG4105BZU	Histidine kinase
Sfum_3273	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Sfum_3274	ENOG4105VB9	50S ribosomal protein l28
Sfum_3277	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Sfum_3278	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Sfum_3279	ENOG4105HHA	aminodeoxychorismate lyase
Sfum_3280	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Sfum_3281	ENOG4105DKW	ABC transporter
Sfum_3283	ENOG4105W5Q	DNA repair protein (RadC
Sfum_3284	ENOG4105E3I	toluene tolerance
Sfum_3285	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Sfum_3286	ENOG4105QAX	Iron-sulfur
Sfum_3287	ENOG4107QY8	reductase
Sfum_3291	ENOG4105C1G	acyl-Coa dehydrogenase
Sfum_3292	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Sfum_3292	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Sfum_3294	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Sfum_3298	ENOG4105VF7	tolerance protein
Sfum_3299	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Sfum_3300	ENOG4105K6T	rare lipoprotein A
Sfum_3301	ENOG4107SDT	Homocitrate synthase
Sfum_3302	ENOG4105C9M	aspartyl-trna synthetase
Sfum_3303	ENOG4105CUT	histidyl-tRNA synthetase
Sfum_3311	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Sfum_3312	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Sfum_3313	ENOG4105DUM	transcriptional regulator, lysR family
Sfum_3314	ENOG4105C5H	ABC transporter
Sfum_3315	ENOG4107YBY	Hydrolase
Sfum_3316	ENOG4105CW7	secretion protein, HlyD family
Sfum_3317	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Sfum_3321	ENOG4108QV3	biosynthesis protein
Sfum_3323	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Sfum_3324	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Sfum_3327	ENOG4105ESV	Glycosyl transferase, family 4
Sfum_3330	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Sfum_3337	ENOG4107RA4	Glycosyl transferase (Group 1
Sfum_3344	ENOG4105E2K	Glycosyl transferase (Group 1
Sfum_3348	ENOG4105K64	Glycosyl transferase, family 2
Sfum_3351	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Sfum_3353	ENOG4107XZA	Glycosyl transferase family 2
Sfum_3354	ENOG4105EY8	ABC transporter
Sfum_3356	ENOG4107QQG	Dehydrogenase
Sfum_3358	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Sfum_3361	ENOG4105C30	Nad-dependent epimerase dehydratase
Sfum_3362	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Sfum_3365	ENOG4105C9M	aspartyl-trna synthetase
Sfum_3366	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Sfum_3367	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Sfum_3370	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Sfum_3374	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Sfum_3375	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
Sfum_3376	ENOG4105CGD	Nad-dependent epimerase dehydratase
Sfum_3382	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Sfum_3387	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Sfum_3392	ENOG4105E7W	lamb ycsf family protein
Sfum_3393	ENOG4105CFM	UPF0317 protein
Sfum_3395	ENOG4105P4J	Allophanate hydrolase, subunit 1
Sfum_3396	ENOG4108IV0	ABC, transporter
Sfum_3397	ENOG4105C0Z	ABC transporter
Sfum_3399	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_3401	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
Sfum_3414	ENOG4105CN9	Peptidase m42 family protein
Sfum_3415	ENOG4105HKU	nucleoside recognition domain-containing protein
Sfum_3419	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Sfum_3425	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Sfum_3430	ENOG4108W2Y	isochorismatase
Sfum_3431	ENOG4105DTD	Dehydrogenase
Sfum_3433	ENOG4108R5S	membrane
Sfum_3434	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Sfum_3435	ENOG4108ZF3	Phosphatase
Sfum_3436	ENOG4105TV9	FHA Domain-Containing protein
Sfum_3437	ENOG4107VAM	peptidase, m28
Sfum_3438	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Sfum_3446	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Sfum_3449	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Sfum_3450	ENOG4105DEU	major facilitator superfamily
Sfum_3451	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Sfum_3454	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Sfum_3458	ENOG4105E09	nadh pyrophosphatase
Sfum_3459	ENOG4107Z3H	Transcriptional regulator, TetR family
Sfum_3460	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Sfum_3462	ENOG4108V6E	Cell division protein mraZ
Sfum_3463	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Sfum_3465	ENOG4105CJN	penicillin-binding protein
Sfum_3466	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Sfum_3467	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Sfum_3468	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Sfum_3469	ENOG4105CNI	cell division protein FtsW
Sfum_3470	ENOG4105DFU	Cell wall formation (By similarity)
Sfum_3471	ENOG4105D4A	Cell wall formation (By similarity)
Sfum_3473	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Sfum_3474	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Sfum_3477	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
Sfum_3479	ENOG4108JA2	transcriptioN-repair coupling factor
Sfum_3480	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Sfum_3482	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
Sfum_3483	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Sfum_3485	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Sfum_3491	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Sfum_3495	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
Sfum_3496	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Sfum_3498	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
Sfum_3499	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
Sfum_3501	ENOG4108I5G	Major Facilitator superfamily
Sfum_3503	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Sfum_3504	ENOG410853W	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Sfum_3507	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Sfum_3508	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Sfum_3509	ENOG4108JB9	formate dehydrogenase
Sfum_3512	ENOG4108ZCF	integral membrane protein
Sfum_3516	ENOG4105CX6	glutaminyL-tRNA synthetase
Sfum_3519	ENOG4105BZU	Histidine kinase
Sfum_3520	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Sfum_3527	ENOG4105EU0	Major facilitator Superfamily
Sfum_3528	ENOG4105EQN	UPF0261 protein
Sfum_3532	ENOG4107QQM	Cysteine-rich domain
Sfum_3536	ENOG4105E3S	small subunit
Sfum_3539	ENOG4105D63	family UPF0324
Sfum_3542	ENOG4105D22	carbon starvation protein
Sfum_3543	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Sfum_3544	ENOG4108JQ7	(ABC) transporter
Sfum_3546	ENOG4107QJZ	Glycosyl transferase, family 2
Sfum_3547	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Sfum_3548	ENOG4105C7S	Dehydrogenase
Sfum_3549	ENOG4107QN2	dihydrolipoyl dehydrogenase
Sfum_3554	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Sfum_3555	ENOG4105BZ1	(ABC) transporter
Sfum_3557	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Sfum_3561	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Sfum_3563	ENOG4105DXX	methyltransferase
Sfum_3564	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Sfum_3566	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Sfum_3569	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Sfum_3570	ENOG4105CHM	Aminotransferase
Sfum_3574	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Sfum_3577	ENOG4105C6F	GntR Family Transcriptional Regulator
Sfum_3578	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Sfum_3581	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Sfum_3582	ENOG4105CHU	acetyl-coa acetyltransferase
Sfum_3583	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Sfum_3584	ENOG4105E39	Enoyl-CoA hydratase
Sfum_3585	ENOG4105D9Q	decarboxylase (Beta subunit)
Sfum_3586	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Sfum_3587	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Sfum_3588	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Sfum_3591	ENOG4107QP8	phosphohexose isomerase
Sfum_3592	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_3597	ENOG4107S21	permease
Sfum_3600	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
Sfum_3601	ENOG4108UXE	Protein tyrosine phosphatase
Sfum_3602	ENOG4105D6J	arsenicaL-resistance protein
Sfum_3604	ENOG4105K63	Thioredoxin
Sfum_3606	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sfum_3607	ENOG4105KST	dependent repressor
Sfum_3613	ENOG4105D1F	ATP-binding protein
Sfum_3614	ENOG4105BZU	Histidine kinase
Sfum_3615	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Sfum_3619	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Sfum_3620	ENOG4107QTZ	amino acid
Sfum_3622	ENOG4108WS4	fmn reductase
Sfum_3624	ENOG4105BZU	Histidine kinase
Sfum_3626	ENOG4105F8V	Hydrolase, tatD family
Sfum_3627	ENOG4108Z03	MAF-like protein
Sfum_3628	ENOG4105DFA	alanine racemase domain protein
Sfum_3630	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Sfum_3631	ENOG4105KC4	UPF0296 protein
Sfum_3632	ENOG4105DSJ	YicC domain protein
Sfum_3634	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Sfum_3635	ENOG4105W49	UPF0434 protein
Sfum_3637	ENOG4108VIA	integral membrane protein
Sfum_3639	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Sfum_3640	ENOG4105K46	50S ribosomal protein l27
Sfum_3641	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sfum_3643	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Sfum_3644	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Sfum_3645	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Sfum_3648	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Sfum_3651	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Sfum_3652	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Sfum_3653	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Sfum_3654	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Sfum_3655	ENOG4108VJ1	Transcriptional regulator (CarD family
Sfum_3656	ENOG4105CTP	PilT protein domain protein
Sfum_3657	ENOG4105C34	Pseudouridine synthase
Sfum_3658	ENOG4105GVR	general secretion pathway protein D
Sfum_3664	ENOG4108VAU	general secretion pathway protein G
Sfum_3665	ENOG4105D7Q	type ii secretion system
Sfum_3666	ENOG4107QHF	type ii secretion system protein e
Sfum_3678	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Sfum_3679	ENOG4105BZS	acriflavin resistance protein
Sfum_3680	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Sfum_3686	ENOG4105C10	Electron transfer flavoprotein
Sfum_3687	ENOG4105BZJ	Electron transfer flavoprotein
Sfum_3688	ENOG4105C1G	acyl-Coa dehydrogenase
Sfum_3689	ENOG4108XG4	DNA-binding transcriptional regulator
Sfum_3692	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Sfum_3697	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Sfum_3698	ENOG4105E0C	molybdate abc transporter
Sfum_3699	ENOG4105GAV	receptor
Sfum_3703	ENOG4105EHG	Permease protein
Sfum_3704	ENOG4105E0A	ABC, transporter
Sfum_3708	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
Sfum_3709	ENOG4105CRQ	synthase (Component I)
Sfum_3710	ENOG4105DDQ	anthranilate synthase
Sfum_3711	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Sfum_3712	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Sfum_3717	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
Sfum_3718	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Sfum_3719	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Sfum_3724	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Sfum_3727	ENOG4105D7A	ATP-binding protein
Sfum_3728	ENOG4105FCD	Major Facilitator
Sfum_3731	ENOG4105K78	MarR family Transcriptional regulator
Sfum_3732	ENOG4107EMZ	glycosyl transferase family
Sfum_3737	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_3738	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Sfum_3742	ENOG4105CRK	lysyL-tRNA synthetase
Sfum_3743	ENOG4105D60	lipoprotein releasing system transmembrane protein
Sfum_3744	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Sfum_3745	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sfum_3747	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Sfum_3748	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Sfum_3749	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Sfum_3751	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Sfum_3752	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Sfum_3765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Sfum_3766	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Sfum_3767	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
Sfum_3769	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Sfum_3776	ENOG4108C33	Resolvase
Sfum_3779	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Sfum_3789	ENOG4105C7H	Helicase, RecD TraA family
Sfum_3790	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Sfum_3845	ENOG4105NI8	Cytosine-specific methyltransferase
Sfum_3849	ENOG4108DT4	serine threonine protein kinase
Sfum_3863	ENOG4107R3N	Filamentation induced by cAMP protein fic
Sfum_3870	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Sfum_3872	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Sfum_3874	ENOG4105C3M	thioredoxin reductase
Sfum_3877	ENOG4108WQI	RNA Polymerase
Sfum_3887	ENOG4105EMN	RNA polymerase sigma factor
Sfum_3891	ENOG4105MAX	Superoxide reductase
Sfum_3894	ENOG4105MJ2	Competence protein
Sfum_3896	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Sfum_3897	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Sfum_3899	ENOG4105CQB	FAD linked oxidase domain protein
Sfum_3900	ENOG4105E5Q	amino acid AbC transporter
Sfum_3901	ENOG4105CDA	abc transporter atp-binding protein
Sfum_3902	ENOG4106YG3	ABC transporter
Sfum_3903	ENOG4106PMH	Extracellular solute-binding protein family 3
Sfum_3906	ENOG4107T8Q	Glycosyl transferase (Group 1
Sfum_3907	ENOG4105JNK	Glycosyl transferase (Group 1
Sfum_3911	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Sfum_3912	ENOG4107FQX	Alpha-acetolactate decarboxylase
Sfum_3914	ENOG4105C5I	Dehydrogenase
Sfum_3915	ENOG4105D1Z	hydroxypyruvate reductase
Sfum_3926	ENOG4105IBM	Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein
Sfum_3927	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Sfum_3928	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Sfum_3931	ENOG4105C1G	acyl-Coa dehydrogenase
Sfum_3933	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
Sfum_3934	ENOG4108JUB	Transcriptional regulator
Sfum_3938	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Sfum_3945	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Sfum_3947	ENOG4105D7T	ABC transporter
Sfum_3950	ENOG4106TNF	Periplasmic binding protein
Sfum_3951	ENOG4105E5Q	amino acid AbC transporter
Sfum_3954	ENOG4105DPX	Hydrogenase, large subunit
Sfum_3980	ENOG4105C0H	protease
Sfum_3988	ENOG4105BZ1	(ABC) transporter
Sfum_3991	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
Sfum_3992	ENOG4108V9W	transcriptional regulatory protein
Sfum_3993	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
Sfum_4003	ENOG4105D64	Mechanosensitive ion channel
Sfum_4004	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Sfum_4011	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Sfum_4014	ENOG4105CQS	hydrogenase expression formation protein HypD
Sfum_4015	ENOG4105C45	hydrogenase expression formation protein (HypE)
Sfum_4017	ENOG4105EYM	Major Facilitator superfamily
Sfum_4019	ENOG4105C5H	ABC transporter
Sfum_4023	ENOG4105C3G	gtp-binding protein
Sfum_4025	ENOG4107QZF	nitrite reductase NADPH large subunit
Sfum_4031	ENOG4105BZ1	(ABC) transporter
Sfum_4033	ENOG41083UI	stage II sporulation protein
Sfum_4039	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Sfum_4042	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
Sfum_4043	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
Sfum_4044	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Sfum_4045	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
Sfum_4046	ENOG4105Z5G	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Sfum_4049	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Sfum_4051	ENOG4105C8N	cysteinyl-tRNA synthetase
Sfum_4052	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Sfum_4053	ENOG4105CHM	Aminotransferase
Sfum_4055	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Sfum_4056	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Sfum_4057	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Sfum_4060	ENOG4105DFF	Rod shape-determining protein mreb
Sfum_4061	ENOG4105DZ1	carboxypeptidase
Sfum_4066	ENOG4105CKK	Glycosyl transferase, family 2
Sfum_4070	ENOG4105C32	Amino acid ABC transporter (Permease)
Sfum_4071	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Sfum_4072	ENOG4105C0Z	ABC transporter
Sfum_4073	ENOG4108IV0	ABC, transporter
Sfum_4074	ENOG4105DZS	Phenylacetate-CoA ligase
Sfum_4077	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Sfum_4080	ENOG4105VZ9	UPF0235 protein
Sfum_4085	ENOG4105F8J	Adenylate Guanylate cyclase
Sfum_4096	ENOG4105K63	Thioredoxin
Sfum_4099	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Sfum_4100	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Sfum_4102	ENOG4105CPF	Cell wall formation (By similarity)