locus-tag	class	description
Pcar_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Pcar_0004	COG0187	DNA topoisomerase II activity
Pcar_0007	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Pcar_0009	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Pcar_0011	COG0436	Aminotransferase
Pcar_0012	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pcar_0015	COG0356	it plays a direct role in the translocation of protons across the membrane
Pcar_0016	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Pcar_0021	COG0822	iron-sulfur transferase activity
Pcar_0022	COG2259	Doxx family
Pcar_0023	COG1199	ATP-dependent helicase activity
Pcar_0024	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pcar_0027	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Pcar_0028	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Pcar_0029	COG0840	transmembrane signaling receptor activity
Pcar_0029	COG5278	phosphoserine phosphatase activity
Pcar_0031	COG2198	Histidine kinase
Pcar_0031	COG0643	Histidine kinase
Pcar_0032	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Pcar_0033	COG1666	GTP binding
Pcar_0034	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Pcar_0035	COG1477	protein flavinylation
Pcar_0038	COG1132	(ABC) transporter
Pcar_0039	COG1132	(ABC) transporter
Pcar_0040	COG0745	RESPONSE REGULATOR receiver
Pcar_0041	COG4145	pantothenate transmembrane transporter activity
Pcar_0046	COG4625	pathogenesis
Pcar_0047	COG0640	Transcriptional regulator
Pcar_0053	COG5002	protein histidine kinase activity
Pcar_0059	COG0437	4 iron, 4 sulfur cluster binding
Pcar_0061	COG0310	cobalt ion transport
Pcar_0064	COG0826	peptidase U32
Pcar_0065	COG2003	Belongs to the UPF0758 family
Pcar_0066	COG1752	Esterase of the alpha-beta hydrolase superfamily
Pcar_0067	COG2239	Acts as a magnesium transporter
Pcar_0071	COG0583	DNA-binding transcription factor activity
Pcar_0080	COG0500	methyltransferase
Pcar_0081	COG4106	trans-aconitate 2-methyltransferase activity
Pcar_0084	COG1592	Rubrerythrin
Pcar_0085	COG0569	domain protein
Pcar_0086	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Pcar_0087	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Pcar_0088	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Pcar_0089	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Pcar_0092	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Pcar_0093	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Pcar_0094	COG0805	protein transport
Pcar_0095	COG5001	Diguanylate cyclase
Pcar_0095	COG4251	negative regulation of phosphorylation
Pcar_0095	COG2203	Gaf domain
Pcar_0095	COG3706	GGDEF domain
Pcar_0096	COG1131	(ABC) transporter
Pcar_0097	COG0842	Transport permease protein
Pcar_0099	COG0556	nucleotide-excision repair
Pcar_0100	COG0215	cysteine-tRNA ligase activity
Pcar_0101	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Pcar_0102	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Pcar_0103	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Pcar_0104	COG1329	Transcriptional regulator
Pcar_0106	COG0484	heat shock protein binding
Pcar_0107	COG0443	Heat shock 70 kDa protein
Pcar_0109	COG1420	regulation of RNA biosynthetic process
Pcar_0110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Pcar_0112	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pcar_0114	COG0492	ferredoxin-NADP+ reductase activity
Pcar_0118	COG3568	Endonuclease Exonuclease Phosphatase
Pcar_0118	COG1555	photosystem II stabilization
Pcar_0130	COG1459	type II secretion system
Pcar_0131	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pcar_0138	COG4968	Prepilin-type N-terminal cleavage methylation domain
Pcar_0144	COG2268	Band 7 protein
Pcar_0148	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Pcar_0150	COG0500	methyltransferase
Pcar_0154	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Pcar_0155	COG1120	ATPase activity
Pcar_0157	COG2226	methyltransferase
Pcar_0161	COG2095	MarC family integral membrane protein
Pcar_0167	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Pcar_0169	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Pcar_0172	COG3384	dioxygenase
Pcar_0175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pcar_0177	COG0569	domain protein
Pcar_0178	COG0475	glutathione-regulated potassium exporter activity
Pcar_0182	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Pcar_0183	COG0640	Transcriptional regulator
Pcar_0186	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
Pcar_0188	COG0729	surface antigen
Pcar_0190	COG0531	amino acid
Pcar_0192	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Pcar_0195	COG4206	TonB-dependent receptor
Pcar_0197	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Pcar_0199	COG0321	lipoyl(octanoyl) transferase activity
Pcar_0199	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Pcar_0200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Pcar_0201	COG1278	Cold shock
Pcar_0202	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Pcar_0203	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Pcar_0204	COG0328	RNA-DNA hybrid ribonuclease activity
Pcar_0205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Pcar_0206	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Pcar_0206	COG0649	NAD binding
Pcar_0210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Pcar_0211	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Pcar_0213	COG0713	ATP synthesis coupled electron transport
Pcar_0214	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Pcar_0215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Pcar_0216	COG1007	ATP synthesis coupled electron transport
Pcar_0219	COG1058	Belongs to the CinA family
Pcar_0219	COG1546	Belongs to the CinA family
Pcar_0225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_0227	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Pcar_0230	COG4149	molybdate abc transporter
Pcar_0231	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Pcar_0234	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Pcar_0235	COG0725	ABC transporter, periplasmic molybdate-binding protein
Pcar_0237	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Pcar_0238	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Pcar_0238	COG0646	methionine synthase
Pcar_0240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Pcar_0241	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Pcar_0241	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Pcar_0242	COG0501	Belongs to the peptidase M48B family
Pcar_0244	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Pcar_0245	COG0242	peptide deformylase activity
Pcar_0246	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Pcar_0247	COG0045	succinate-CoA ligase (ADP-forming) activity
Pcar_0248	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Pcar_0250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Pcar_0251	COG1454	alcohol dehydrogenase
Pcar_0252	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Pcar_0255	COG1454	alcohol dehydrogenase
Pcar_0256	COG0303	'Molybdopterin
Pcar_0258	COG5002	protein histidine kinase activity
Pcar_0260	COG4660	Part of a membrane complex involved in electron transport
Pcar_0262	COG4658	electron transport chain
Pcar_0263	COG4656	Part of a membrane complex involved in electron transport
Pcar_0264	COG2878	Part of a membrane complex involved in electron transport
Pcar_0264	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
Pcar_0265	COG4657	Part of a membrane complex involved in electron transport
Pcar_0266	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Pcar_0267	COG0577	efflux transmembrane transporter activity
Pcar_0267	COG1136	(ABC) transporter
Pcar_0269	COG1136	(ABC) transporter
Pcar_0269	COG4591	ABC-type transport system involved in lipoprotein release permease component
Pcar_0270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pcar_0271	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Pcar_0272	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Pcar_0273	COG4399	Belongs to the UPF0754 family
Pcar_0276	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Pcar_0277	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Pcar_0278	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Pcar_0286	COG1309	transcriptional regulator
Pcar_0288	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Pcar_0291	COG0314	molybdopterin synthase activity
Pcar_0297	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Pcar_0302	COG0670	Belongs to the BI1 family
Pcar_0304	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Pcar_0308	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Pcar_0311	COG4520	surface antigen
Pcar_0312	COG0745	RESPONSE REGULATOR receiver
Pcar_0313	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Pcar_0314	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Pcar_0316	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Pcar_0318	COG0163	prenyltransferase activity
Pcar_0319	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Pcar_0320	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Pcar_0321	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Pcar_0323	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Pcar_0324	COG0114	fumarate hydratase activity
Pcar_0326	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Pcar_0330	COG1063	alcohol dehydrogenase
Pcar_0334	COG1993	acr, cog1993
Pcar_0336	COG3284	Transcriptional regulator
Pcar_0337	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Pcar_0339	COG2022	thiamine diphosphate biosynthetic process
Pcar_0340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pcar_0341	COG3199	ATP-NAD kinase
Pcar_0342	COG0351	phosphomethylpyrimidine kinase
Pcar_0342	COG0352	thiamine-phosphate diphosphorylase activity
Pcar_0343	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Pcar_0344	COG0022	dehydrogenase e1 component
Pcar_0345	COG0508	dehydrogenase complex catalyzes the overall conversion of
Pcar_0346	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Pcar_0347	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Pcar_0349	COG1250	3-hydroxyacyl-CoA dehydrogenase
Pcar_0350	COG0321	lipoyl(octanoyl) transferase activity
Pcar_0351	COG0596	Alpha beta hydrolase
Pcar_0355	COG1657	PFAM Prenyltransferase squalene oxidase
Pcar_0359	COG0542	response to heat
Pcar_0360	COG0745	RESPONSE REGULATOR receiver
Pcar_0361	COG2205	protein histidine kinase activity
Pcar_0366	COG1136	(ABC) transporter
Pcar_0366	COG0577	efflux transmembrane transporter activity
Pcar_0367	COG0577	efflux transmembrane transporter activity
Pcar_0367	COG1136	(ABC) transporter
Pcar_0368	COG0513	Belongs to the DEAD box helicase family
Pcar_0369	COG0071	Belongs to the small heat shock protein (HSP20) family
Pcar_0372	COG1278	Cold shock
Pcar_0374	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Pcar_0375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Pcar_0376	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Pcar_0377	COG0674	pyruvate-flavodoxin oxidoreductase activity
Pcar_0377	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Pcar_0377	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Pcar_0377	COG1013	pyruvate-flavodoxin oxidoreductase activity
Pcar_0379	COG1100	Small GTP-binding protein
Pcar_0380	COG3108	Peptidase M15
Pcar_0386	COG3267	Type II secretory pathway component ExeA
Pcar_0386	COG3409	Peptidoglycan-binding domain 1 protein
Pcar_0388	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pcar_0389	COG1459	type II secretion system
Pcar_0391	COG2165	general secretion pathway protein
Pcar_0392	COG2165	general secretion pathway protein
Pcar_0397	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Pcar_0402	COG0733	neurotransmitter:sodium symporter activity
Pcar_0403	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Pcar_0404	COG0424	maF-like protein
Pcar_0405	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Pcar_0406	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Pcar_0408	COG0758	DNA mediated transformation
Pcar_0410	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Pcar_0411	COG0826	peptidase U32
Pcar_0413	COG1597	lipid kinase activity
Pcar_0414	COG0494	nUDIX hydrolase
Pcar_0416	COG0686	Belongs to the AlaDH PNT family
Pcar_0417	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Pcar_0422	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Pcar_0429	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pcar_0431	COG0488	(ABC) transporter
Pcar_0436	COG1309	transcriptional regulator
Pcar_0437	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Pcar_0439	COG0840	transmembrane signaling receptor activity
Pcar_0440	COG1309	transcriptional regulator
Pcar_0441	COG1657	PFAM Prenyltransferase squalene oxidase
Pcar_0442	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Pcar_0443	COG0004	ammonium transporteR
Pcar_0445	COG1053	succinate dehydrogenase
Pcar_0447	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Pcar_0448	COG1127	ABC transporter
Pcar_0450	COG2853	Lipoprotein
Pcar_0454	COG4206	TonB-dependent receptor
Pcar_0462	COG0714	Associated with various cellular activities
Pcar_0463	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Pcar_0465	COG1120	ATPase activity
Pcar_0467	COG4303	Ethanolamine ammonia lyase large subunit
Pcar_0475	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Pcar_0481	COG1797	cobyrinic acid a,c-diamide synthase activity
Pcar_0482	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Pcar_0483	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Pcar_0485	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Pcar_0486	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Pcar_0489	COG1648	precorrin-2 dehydrogenase activity
Pcar_0489	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Pcar_0494	COG1242	4 iron, 4 sulfur cluster binding
Pcar_0496	COG2205	protein histidine kinase activity
Pcar_0498	COG2204	response regulator
Pcar_0500	COG0778	Nitroreductase
Pcar_0507	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Pcar_0512	COG1785	Belongs to the alkaline phosphatase family
Pcar_0515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Pcar_0516	COG2824	Alkylphosphonate utilization operon protein PhnA
Pcar_0521	COG3864	Putative metallopeptidase domain
Pcar_0524	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Pcar_0530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Pcar_0536	COG2801	Transposase and inactivated derivatives
Pcar_0536	COG3415	Transposase
Pcar_0539	COG2801	Transposase and inactivated derivatives
Pcar_0543	COG4953	penicillin-binding protein 1C
Pcar_0544	COG2373	Large extracellular alpha-helical protein
Pcar_0545	COG0840	transmembrane signaling receptor activity
Pcar_0546	COG0835	chemotaxis
Pcar_0550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Pcar_0552	COG1584	GPR1 FUN34 yaaH family protein
Pcar_0553	COG0322	excinuclease ABC activity
Pcar_0556	COG1469	GTP cyclohydrolase I activity
Pcar_0557	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Pcar_0558	COG2010	Cytochrome c
Pcar_0561	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Pcar_0561	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Pcar_0569	COG3706	GGDEF domain
Pcar_0569	COG5001	Diguanylate cyclase
Pcar_0569	COG2203	Gaf domain
Pcar_0569	COG4251	negative regulation of phosphorylation
Pcar_0570	COG0513	Belongs to the DEAD box helicase family
Pcar_0575	COG0473	3-isopropylmalate dehydrogenase activity
Pcar_0583	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Pcar_0585	COG0840	transmembrane signaling receptor activity
Pcar_0591	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Pcar_0592	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Pcar_0592	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Pcar_0596	COG2239	Acts as a magnesium transporter
Pcar_0597	COG1381	Involved in DNA repair and RecF pathway recombination
Pcar_0598	COG0752	glycyl-tRNA synthetase alpha subunit
Pcar_0599	COG0751	glycine-tRNA ligase activity
Pcar_0600	COG0574	Belongs to the PEP-utilizing enzyme family
Pcar_0600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Pcar_0602	COG1515	deoxyribonuclease V activity
Pcar_0603	COG0179	Fumarylacetoacetate (FAA) hydrolase
Pcar_0604	COG2860	membrane
Pcar_0606	COG0471	metal ion transport
Pcar_0606	COG3273	potassium ion transport
Pcar_0607	COG0352	thiamine-phosphate diphosphorylase activity
Pcar_0608	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pcar_0609	COG2022	thiamine diphosphate biosynthetic process
Pcar_0611	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Pcar_0614	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Pcar_0615	COG0762	integral membrane protein
Pcar_0617	COG1872	DUF167
Pcar_0620	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Pcar_0621	COG0432	Pfam Uncharacterised protein family UPF0047
Pcar_0623	COG4974	Belongs to the 'phage' integrase family
Pcar_0631	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Pcar_0634	COG2199	diguanylate cyclase activity
Pcar_0634	COG2203	Gaf domain
Pcar_0637	COG0471	metal ion transport
Pcar_0637	COG3273	potassium ion transport
Pcar_0639	COG0471	metal ion transport
Pcar_0642	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Pcar_0643	COG0629	single-stranded DNA binding
Pcar_0646	COG1968	undecaprenyl-diphosphatase activity
Pcar_0647	COG1674	ftsk spoiiie
Pcar_0649	COG0330	HflC and HflK could
Pcar_0650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Pcar_0651	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Pcar_0654	COG5002	protein histidine kinase activity
Pcar_0657	COG0573	inorganic phosphate transmembrane transporter activity
Pcar_0658	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Pcar_0659	COG0704	Plays a role in the regulation of phosphate uptake
Pcar_0665	COG2414	aldehyde ferredoxin oxidoreductase
Pcar_0671	COG0037	tRNA processing
Pcar_0678	COG0543	2 iron, 2 sulfur cluster binding
Pcar_0680	COG0436	Aminotransferase
Pcar_0681	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pcar_0682	COG0442	prolyl-tRNA aminoacylation
Pcar_0684	COG0284	orotidine-5'-phosphate decarboxylase activity
Pcar_0686	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Pcar_0687	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Pcar_0690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Pcar_0691	COG0081	regulation of translation
Pcar_0692	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Pcar_0693	COG0222	ribosome binding
Pcar_0694	COG0085	RNA polymerase activity
Pcar_0695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Pcar_0696	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Pcar_0697	COG0049	tRNA binding
Pcar_0698	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Pcar_0699	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Pcar_0700	COG0051	transcription antitermination factor activity, RNA binding
Pcar_0701	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Pcar_0702	COG0088	Forms part of the polypeptide exit tunnel
Pcar_0703	COG0089	rRNA binding
Pcar_0704	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Pcar_0705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Pcar_0706	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Pcar_0707	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Pcar_0708	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Pcar_0709	COG0255	Belongs to the universal ribosomal protein uL29 family
Pcar_0710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Pcar_0711	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Pcar_0712	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Pcar_0713	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Pcar_0714	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Pcar_0715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Pcar_0716	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Pcar_0717	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Pcar_0718	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Pcar_0719	COG1841	ribosomal large subunit assembly
Pcar_0720	COG0200	Binds to the 23S rRNA
Pcar_0721	COG0201	protein transport
Pcar_0722	COG0563	adenylate kinase activity
Pcar_0723	COG0024	Methionine aminopeptidase
Pcar_0724	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Pcar_0725	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Pcar_0726	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Pcar_0727	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Pcar_0728	COG0202	RNA polymerase activity
Pcar_0729	COG0203	ribosomal protein L17
Pcar_0732	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Pcar_0733	COG0134	indole-3-glycerol-phosphate synthase activity
Pcar_0734	COG0135	phosphoribosylanthranilate isomerase activity
Pcar_0736	COG1573	uracil-dna glycosylase
Pcar_0737	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Pcar_0738	COG0285	dihydrofolate synthase activity
Pcar_0739	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Pcar_0742	COG0018	arginyl-trna synthetase
Pcar_0744	COG1509	lysine 2,3-aminomutase activity
Pcar_0745	COG0489	protein tyrosine kinase activity
Pcar_0748	COG0489	protein tyrosine kinase activity
Pcar_0752	COG0493	'glutamate synthase
Pcar_0753	COG0543	2 iron, 2 sulfur cluster binding
Pcar_0755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pcar_0757	COG0237	dephospho-CoA kinase activity
Pcar_0759	COG1414	Transcriptional regulator
Pcar_0760	COG0585	pseudouridine synthase activity
Pcar_0761	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Pcar_0762	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Pcar_0763	COG1408	metallophosphoesterase
Pcar_0764	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Pcar_0767	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pcar_0768	COG0745	RESPONSE REGULATOR receiver
Pcar_0769	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Pcar_0770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Pcar_0773	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Pcar_0775	COG0725	ABC transporter, periplasmic molybdate-binding protein
Pcar_0776	COG4149	molybdate abc transporter
Pcar_0777	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Pcar_0778	COG1278	Cold shock
Pcar_0779	COG3613	nucleoside 2-deoxyribosyltransferase
Pcar_0783	COG2814	Major facilitator Superfamily
Pcar_0784	COG1280	lysine exporter protein (LysE YggA)
Pcar_0803	COG2003	Belongs to the UPF0758 family
Pcar_0812	COG0668	transmembrane transport
Pcar_0813	COG1309	transcriptional regulator
Pcar_0815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pcar_0816	COG0577	efflux transmembrane transporter activity
Pcar_0816	COG1136	(ABC) transporter
Pcar_0817	COG1136	(ABC) transporter
Pcar_0817	COG0577	efflux transmembrane transporter activity
Pcar_0821	COG0425	Belongs to the sulfur carrier protein TusA family
Pcar_0824	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Pcar_0826	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Pcar_0827	COG0573	inorganic phosphate transmembrane transporter activity
Pcar_0829	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Pcar_0831	COG0583	DNA-binding transcription factor activity
Pcar_0833	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Pcar_0837	COG1151	hydroxylamine reductase activity
Pcar_0841	COG3344	reverse transcriptase
Pcar_0846	COG0848	biopolymer transport protein
Pcar_0847	COG0811	peptide transport
Pcar_0848	COG0811	peptide transport
Pcar_0852	COG4771	TonB-dependent receptor
Pcar_0855	COG1116	anion transmembrane transporter activity
Pcar_0860	COG0716	FMN binding
Pcar_0863	COG2165	general secretion pathway protein
Pcar_0872	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pcar_0873	COG1459	type II secretion system
Pcar_0882	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Pcar_0882	COG1918	ferrous iron import across plasma membrane
Pcar_0884	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Pcar_0885	COG0463	Glycosyl transferase, family 2
Pcar_0885	COG1216	Glycosyl transferase, family 2
Pcar_0886	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pcar_0887	COG0437	4 iron, 4 sulfur cluster binding
Pcar_0889	COG1959	2 iron, 2 sulfur cluster binding
Pcar_0892	COG1937	Protein conserved in bacteria
Pcar_0894	COG0395	ABC-type sugar transport system, permease component
Pcar_0895	COG3842	ATPase activity
Pcar_0896	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Pcar_0897	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Pcar_0900	COG2852	Protein conserved in bacteria
Pcar_0902	COG3284	Transcriptional regulator
Pcar_0905	COG3530	Putative quorum-sensing-regulated virulence factor
Pcar_0906	COG4608	Belongs to the ABC transporter superfamily
Pcar_0907	COG0444	Belongs to the ABC transporter superfamily
Pcar_0923	COG0363	glucosamine-6-phosphate deaminase activity
Pcar_0924	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Pcar_0925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Pcar_0932	COG0528	UMP kinase activity
Pcar_0937	COG1882	Formate acetyltransferase
Pcar_0940	COG1349	DNA-binding transcription factor activity
Pcar_0941	COG0697	spore germination
Pcar_0943	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Pcar_0945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Pcar_0946	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Pcar_0947	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Pcar_0948	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Pcar_0949	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Pcar_0950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Pcar_0951	COG0356	it plays a direct role in the translocation of protons across the membrane
Pcar_0952	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Pcar_0954	COG2226	methyltransferase
Pcar_0956	COG1203	CRISPR-associated helicase, Cas3
Pcar_0959	COG1857	crispr-associated protein
Pcar_0962	COG2337	Toxic component of a toxin-antitoxin (TA) module
Pcar_0964	COG1518	maintenance of DNA repeat elements
Pcar_0965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Pcar_0972	COG0840	transmembrane signaling receptor activity
Pcar_0976	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Pcar_0977	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Pcar_0978	COG2197	response regulator
Pcar_0979	COG5002	protein histidine kinase activity
Pcar_0981	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Pcar_0982	COG1993	acr, cog1993
Pcar_0985	COG2135	peptidase activity
Pcar_0986	COG3385	transposase activity
Pcar_0988	COG1192	Involved in chromosome partitioning
Pcar_0993	COG2252	PERMEase
Pcar_0995	COG0835	chemotaxis
Pcar_0996	COG0037	tRNA processing
Pcar_0997	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pcar_0998	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Pcar_0999	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Pcar_1000	COG4856	YbbR-like protein
Pcar_1001	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Pcar_1002	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Pcar_1003	COG0736	holo-[acyl-carrier-protein] synthase activity
Pcar_1004	COG0617	tRNA 3'-terminal CCA addition
Pcar_1004	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Pcar_1004	COG0517	IMP dehydrogenase activity
Pcar_1005	COG0802	atpase or kinase
Pcar_1007	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Pcar_1011	COG0784	Response regulator, receiver
Pcar_1011	COG2198	Histidine kinase
Pcar_1011	COG5002	protein histidine kinase activity
Pcar_1017	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pcar_1018	COG2957	Belongs to the agmatine deiminase family
Pcar_1019	COG0586	Pfam SNARE associated Golgi protein
Pcar_1020	COG1067	ATP-dependent peptidase activity
Pcar_1022	COG0004	ammonium transporteR
Pcar_1027	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Pcar_1029	COG1013	pyruvate-flavodoxin oxidoreductase activity
Pcar_1030	COG0674	pyruvate-flavodoxin oxidoreductase activity
Pcar_1030	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Pcar_1033	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Pcar_1034	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Pcar_1034	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Pcar_1034	COG0674	pyruvate-flavodoxin oxidoreductase activity
Pcar_1034	COG1013	pyruvate-flavodoxin oxidoreductase activity
Pcar_1037	COG0039	L-malate dehydrogenase activity
Pcar_1038	COG0538	isocitrate dehydrogenase activity
Pcar_1040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Pcar_1041	COG0124	histidyl-tRNA synthetase
Pcar_1045	COG0772	Belongs to the SEDS family
Pcar_1049	COG1077	Cell shape determining protein MreB Mrl
Pcar_1050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Pcar_1051	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Pcar_1053	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Pcar_1055	COG2203	Gaf domain
Pcar_1055	COG5001	Diguanylate cyclase
Pcar_1055	COG3706	GGDEF domain
Pcar_1055	COG4251	negative regulation of phosphorylation
Pcar_1056	COG0784	Response regulator, receiver
Pcar_1056	COG2205	protein histidine kinase activity
Pcar_1056	COG5002	protein histidine kinase activity
Pcar_1058	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Pcar_1061	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Pcar_1062	COG0537	adenosine 5'-monophosphoramidase activity
Pcar_1063	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Pcar_1066	COG2226	methyltransferase
Pcar_1068	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Pcar_1069	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Pcar_1071	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Pcar_1074	COG1012	belongs to the aldehyde dehydrogenase family
Pcar_1075	COG2989	Protein conserved in bacteria
Pcar_1081	COG1028	Short-chain dehydrogenase reductase Sdr
Pcar_1083	COG2207	Transcriptional regulator
Pcar_1087	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pcar_1087	COG1902	pentaerythritol trinitrate reductase activity
Pcar_1088	COG1733	regulation of RNA biosynthetic process
Pcar_1089	COG0583	DNA-binding transcription factor activity
Pcar_1091	COG2207	Transcriptional regulator
Pcar_1095	COG1979	alcohol dehydrogenase
Pcar_1098	COG0667	Aldo Keto reductase
Pcar_1102	COG2814	Major facilitator Superfamily
Pcar_1103	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Pcar_1104	COG0655	NAD(P)H dehydrogenase (quinone) activity
Pcar_1105	COG2257	FlhB HrpN YscU SpaS Family
Pcar_1113	COG1334	flagellar protein FlaG
Pcar_1114	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Pcar_1115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Pcar_1117	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Pcar_1117	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pcar_1118	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Pcar_1119	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Pcar_1120	COG1028	Short-chain dehydrogenase reductase Sdr
Pcar_1121	COG0028	Belongs to the TPP enzyme family
Pcar_1122	COG1215	transferase activity, transferring glycosyl groups
Pcar_1124	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_1126	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_1132	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Pcar_1134	COG1032	radical SAM domain protein
Pcar_1137	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Pcar_1138	COG0667	Aldo Keto reductase
Pcar_1139	COG1028	Short-chain dehydrogenase reductase Sdr
Pcar_1140	COG2089	acid synthase
Pcar_1141	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Pcar_1142	COG1086	Polysaccharide biosynthesis protein
Pcar_1146	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Pcar_1147	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pcar_1148	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Pcar_1153	COG1706	bacterial-type flagellum-dependent cell motility
Pcar_1154	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Pcar_1159	COG1191	sigma factor activity
Pcar_1161	COG1419	protein localization to endoplasmic reticulum
Pcar_1162	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Pcar_1163	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Pcar_1164	COG1684	flagellar biosynthetic protein fliR
Pcar_1166	COG1338	Plays a role in the flagellum-specific transport system
Pcar_1168	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Pcar_1168	COG1776	CheC inhibitor of MCP methylation
Pcar_1171	COG1360	Flagellar Motor Protein
Pcar_1172	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Pcar_1175	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Pcar_1177	COG2203	Gaf domain
Pcar_1177	COG2199	diguanylate cyclase activity
Pcar_1179	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pcar_1181	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Pcar_1181	COG1672	PFAM Archaeal ATPase
Pcar_1185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Pcar_1189	COG1157	protein secretion by the type III secretion system
Pcar_1190	COG1317	bacterial-type flagellum organization
Pcar_1191	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Pcar_1192	COG1766	The M ring may be actively involved in energy transduction
Pcar_1193	COG1677	Flagellar hook-basal body complex protein FliE
Pcar_1195	COG1815	bacterial-type flagellum-dependent cell motility
Pcar_1197	COG0643	Histidine kinase
Pcar_1197	COG2198	Histidine kinase
Pcar_1200	COG2201	protein-glutamate methylesterase activity
Pcar_1201	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Pcar_1203	COG0745	RESPONSE REGULATOR receiver
Pcar_1205	COG0745	RESPONSE REGULATOR receiver
Pcar_1210	COG2078	PFAM AMMECR1 domain protein
Pcar_1211	COG1217	gtp-binding protein TYPA
Pcar_1214	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Pcar_1215	COG0587	DNA-directed DNA polymerase activity
Pcar_1216	COG1363	Peptidase, m42
Pcar_1217	COG0516	GMP reductase activity
Pcar_1217	COG0517	IMP dehydrogenase activity
Pcar_1218	COG0519	Catalyzes the synthesis of GMP from XMP
Pcar_1218	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Pcar_1221	COG0424	maF-like protein
Pcar_1222	COG0587	DNA-directed DNA polymerase activity
Pcar_1223	COG0825	malonyl-CoA metabolic process
Pcar_1224	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Pcar_1225	COG5001	Diguanylate cyclase
Pcar_1225	COG3300	MHYT domain
Pcar_1226	COG1929	Belongs to the glycerate kinase type-1 family
Pcar_1228	COG0343	queuine tRNA-ribosyltransferase activity
Pcar_1229	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pcar_1230	COG0148	phosphopyruvate hydratase activity
Pcar_1232	COG1480	7TM receptor with intracellular HD hydrolase
Pcar_1233	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Pcar_1234	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Pcar_1235	COG4535	Mg2 and Co2 transporter CorC
Pcar_1236	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Pcar_1237	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Pcar_1238	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Pcar_1239	COG0674	pyruvate-flavodoxin oxidoreductase activity
Pcar_1241	COG0318	PFAM AMP-dependent synthetase and ligase
Pcar_1242	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Pcar_1244	COG0133	tryptophan synthase activity
Pcar_1245	COG0697	spore germination
Pcar_1246	COG1012	belongs to the aldehyde dehydrogenase family
Pcar_1246	COG1454	alcohol dehydrogenase
Pcar_1248	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Pcar_1249	COG4591	ABC-type transport system involved in lipoprotein release permease component
Pcar_1250	COG1136	(ABC) transporter
Pcar_1251	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Pcar_1253	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pcar_1254	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Pcar_1256	COG0673	inositol 2-dehydrogenase activity
Pcar_1258	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pcar_1259	COG1132	(ABC) transporter
Pcar_1260	COG1519	Transferase
Pcar_1261	COG1663	tetraacyldisaccharide 4'-kinase activity
Pcar_1262	COG2835	tetraacyldisaccharide 4'-kinase activity
Pcar_1263	COG0859	PFAM glycosyl transferase family 9
Pcar_1264	COG0859	PFAM glycosyl transferase family 9
Pcar_1267	COG1215	transferase activity, transferring glycosyl groups
Pcar_1270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Pcar_1273	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Pcar_1274	COG0438	transferase activity, transferring glycosyl groups
Pcar_1275	COG3642	lipopolysaccharide core region biosynthetic process
Pcar_1277	COG2089	acid synthase
Pcar_1278	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Pcar_1282	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Pcar_1282	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Pcar_1283	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Pcar_1284	COG1561	YicC-like family, N-terminal region
Pcar_1285	COG0194	GDP metabolic process
Pcar_1286	COG1758	RNA polymerase activity
Pcar_1289	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Pcar_1292	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Pcar_1293	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Pcar_1295	COG0543	2 iron, 2 sulfur cluster binding
Pcar_1296	COG0167	dihydroorotate dehydrogenase activity
Pcar_1297	COG3620	sequence-specific DNA binding
Pcar_1297	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Pcar_1297	COG0617	tRNA 3'-terminal CCA addition
Pcar_1298	COG1994	Peptidase M50
Pcar_1299	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Pcar_1300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Pcar_1301	COG1187	pseudouridine synthase activity
Pcar_1303	COG3409	Peptidoglycan-binding domain 1 protein
Pcar_1303	COG3267	Type II secretory pathway component ExeA
Pcar_1304	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Pcar_1305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Pcar_1311	COG0033	Phosphoglucomutase
Pcar_1316	COG3344	reverse transcriptase
Pcar_1318	COG1472	Belongs to the glycosyl hydrolase 3 family
Pcar_1320	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Pcar_1321	COG0741	lytic transglycosylase activity
Pcar_1322	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Pcar_1325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Pcar_1326	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Pcar_1327	COG0047	phosphoribosylformylglycinamidine synthase activity
Pcar_1328	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Pcar_1329	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Pcar_1332	COG0126	phosphoglycerate kinase activity
Pcar_1333	COG0149	triose-phosphate isomerase activity
Pcar_1335	COG3344	reverse transcriptase
Pcar_1336	COG0840	transmembrane signaling receptor activity
Pcar_1338	COG3123	guanosine phosphorylase activity
Pcar_1351	COG2801	Transposase and inactivated derivatives
Pcar_1351	COG3415	Transposase
Pcar_1356	COG0604	alcohol dehydrogenase
Pcar_1361	COG0488	(ABC) transporter
Pcar_1363	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Pcar_1371	COG0791	NLP P60 protein
Pcar_1373	COG3344	reverse transcriptase
Pcar_1375	COG0419	ATPase involved in DNA repair
Pcar_1376	COG0644	oxidoreductase
Pcar_1381	COG3415	Transposase
Pcar_1381	COG2801	Transposase and inactivated derivatives
Pcar_1388	COG1011	Hydrolase
Pcar_1390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Pcar_1391	COG1881	PFAM PEBP family protein
Pcar_1393	COG0501	Belongs to the peptidase M48B family
Pcar_1394	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_1396	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Pcar_1397	COG1882	Formate acetyltransferase
Pcar_1399	COG5002	protein histidine kinase activity
Pcar_1400	COG2197	response regulator
Pcar_1403	COG0571	ribonuclease III activity
Pcar_1406	COG1160	GTP binding
Pcar_1408	COG2198	Histidine kinase
Pcar_1408	COG0643	Histidine kinase
Pcar_1409	COG0745	RESPONSE REGULATOR receiver
Pcar_1411	COG0745	RESPONSE REGULATOR receiver
Pcar_1412	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Pcar_1413	COG0495	leucyl-tRNA aminoacylation
Pcar_1416	COG0268	Binds directly to 16S ribosomal RNA
Pcar_1418	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Pcar_1419	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Pcar_1420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Pcar_1421	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Pcar_1422	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Pcar_1423	COG0072	phenylalanine-tRNA ligase activity
Pcar_1424	COG0776	regulation of translation
Pcar_1426	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Pcar_1427	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Pcar_1429	COG4942	peptidase
Pcar_1430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pcar_1431	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Pcar_1432	COG3956	TIGRFAM MazG family protein
Pcar_1434	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Pcar_1435	COG0416	fatty acid biosynthetic process
Pcar_1437	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Pcar_1439	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pcar_1440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pcar_1441	COG0698	ribose 5-phosphate isomerase
Pcar_1442	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Pcar_1443	COG2131	deaminase
Pcar_1444	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Pcar_1445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Pcar_1445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Pcar_1447	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Pcar_1447	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Pcar_1448	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Pcar_1449	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Pcar_1452	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Pcar_1453	COG2873	o-acetylhomoserine
Pcar_1454	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Pcar_1455	COG0776	regulation of translation
Pcar_1458	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pcar_1459	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Pcar_1461	COG1335	isochorismatase
Pcar_1464	COG0489	protein tyrosine kinase activity
Pcar_1464	COG3206	protein involved in exopolysaccharide biosynthesis
Pcar_1469	COG0617	tRNA 3'-terminal CCA addition
Pcar_1471	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pcar_1473	COG1943	Transposase
Pcar_1475	COG0739	heme binding
Pcar_1477	COG0346	lactoylglutathione lyase activity
Pcar_1480	COG0023	Translation Initiation Factor
Pcar_1482	COG0067	glutamate synthase
Pcar_1482	COG0069	glutamate synthase activity
Pcar_1482	COG0070	glutamate synthase
Pcar_1483	COG0493	'glutamate synthase
Pcar_1483	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Pcar_1487	COG3174	membrane
Pcar_1488	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Pcar_1489	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Pcar_1495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pcar_1496	COG1012	belongs to the aldehyde dehydrogenase family
Pcar_1497	COG1663	tetraacyldisaccharide 4'-kinase activity
Pcar_1499	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Pcar_1505	COG0811	peptide transport
Pcar_1506	COG0848	biopolymer transport protein
Pcar_1509	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Pcar_1510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Pcar_1511	COG0860	N-Acetylmuramoyl-L-alanine amidase
Pcar_1513	COG4974	Belongs to the 'phage' integrase family
Pcar_1514	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Pcar_1519	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Pcar_1521	COG0622	Phosphoesterase
Pcar_1524	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Pcar_1529	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Pcar_1530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Pcar_1538	COG1596	polysaccharide export
Pcar_1539	COG0489	protein tyrosine kinase activity
Pcar_1540	COG4464	protein tyrosine phosphatase activity
Pcar_1545	COG0674	pyruvate-flavodoxin oxidoreductase activity
Pcar_1545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Pcar_1549	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Pcar_1551	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Pcar_1552	COG0779	Required for maturation of 30S ribosomal subunits
Pcar_1553	COG0195	Participates in both transcription termination and antitermination
Pcar_1555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Pcar_1557	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Pcar_1558	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Pcar_1559	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Pcar_1560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Pcar_1561	COG1185	polyribonucleotide nucleotidyltransferase activity
Pcar_1562	COG0612	Peptidase, M16
Pcar_1563	COG0756	dUTP diphosphatase activity
Pcar_1564	COG0009	L-threonylcarbamoyladenylate synthase
Pcar_1565	COG1283	sodium-dependent phosphate transmembrane transporter activity
Pcar_1566	COG0248	Ppx GppA phosphatase
Pcar_1569	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Pcar_1573	COG0436	Aminotransferase
Pcar_1575	COG1131	(ABC) transporter
Pcar_1579	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pcar_1585	COG0489	protein tyrosine kinase activity
Pcar_1586	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Pcar_1586	COG0731	radical SAM domain protein
Pcar_1587	COG2226	methyltransferase
Pcar_1590	COG0489	protein tyrosine kinase activity
Pcar_1593	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Pcar_1594	COG1454	alcohol dehydrogenase
Pcar_1597	COG0583	DNA-binding transcription factor activity
Pcar_1598	COG2855	membrane
Pcar_1599	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Pcar_1607	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pcar_1609	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Pcar_1611	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Pcar_1613	COG0505	Belongs to the CarA family
Pcar_1614	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Pcar_1615	COG0540	Belongs to the ATCase OTCase family
Pcar_1616	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Pcar_1618	COG0481	GTPase activity
Pcar_1619	COG1022	Amp-dependent synthetase and ligase
Pcar_1624	COG0778	Nitroreductase
Pcar_1629	COG1160	GTP binding
Pcar_1630	COG1027	Aspartate ammonia-lyase
Pcar_1632	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pcar_1637	COG1534	Rna-binding protein
Pcar_1638	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Pcar_1639	COG0742	ribosomal rna small subunit methyltransferase
Pcar_1640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Pcar_1642	COG0602	queuosine metabolic process
Pcar_1643	COG0720	synthase
Pcar_1644	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Pcar_1645	COG0617	tRNA 3'-terminal CCA addition
Pcar_1648	COG0123	including yeast histone deacetylase and acetoin utilization protein
Pcar_1649	COG0308	aminopeptidase N
Pcar_1650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Pcar_1651	COG1355	regulation of microtubule-based process
Pcar_1659	COG1227	inorganic diphosphatase activity
Pcar_1659	COG0517	IMP dehydrogenase activity
Pcar_1662	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Pcar_1663	COG2226	methyltransferase
Pcar_1664	COG0596	Alpha beta hydrolase
Pcar_1665	COG0156	8-amino-7-oxononanoate synthase activity
Pcar_1666	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
Pcar_1667	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Pcar_1669	COG1722	exodeoxyribonuclease VII activity
Pcar_1670	COG1570	exodeoxyribonuclease VII activity
Pcar_1671	COG1192	Involved in chromosome partitioning
Pcar_1672	COG2861	carbohydrate metabolic process
Pcar_1673	COG0793	Belongs to the peptidase S41A family
Pcar_1675	COG2177	Part of the ABC transporter FtsEX involved in
Pcar_1676	COG2884	Cell division ATP-binding protein ftsE
Pcar_1679	COG1450	Type ii and iii secretion system protein
Pcar_1684	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pcar_1685	COG1459	type II secretion system
Pcar_1687	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Pcar_1688	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Pcar_1689	COG0740	serine-type endopeptidase activity
Pcar_1690	COG0544	peptidyl-prolyl cis-trans isomerase activity
Pcar_1691	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Pcar_1693	COG1774	PSP1 C-terminal conserved region
Pcar_1694	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Pcar_1694	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Pcar_1695	COG0084	hydrolase, TatD family'
Pcar_1700	COG1979	alcohol dehydrogenase
Pcar_1708	COG1074	ATP-dependent DNA helicase activity
Pcar_1720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Pcar_1722	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pcar_1723	COG3083	sulfuric ester hydrolase activity
Pcar_1725	COG5000	phosphorelay sensor kinase activity
Pcar_1725	COG5002	protein histidine kinase activity
Pcar_1727	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Pcar_1729	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Pcar_1731	COG0058	SHG alpha-glucan phosphorylase activity
Pcar_1732	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Pcar_1733	COG0667	Aldo Keto reductase
Pcar_1734	COG3284	Transcriptional regulator
Pcar_1735	COG3842	ATPase activity
Pcar_1739	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Pcar_1740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Pcar_1741	COG0587	DNA-directed DNA polymerase activity
Pcar_1747	COG4964	Belongs to the GSP D family
Pcar_1758	COG0463	Glycosyl transferase, family 2
Pcar_1764	COG0326	Molecular chaperone. Has ATPase activity
Pcar_1765	COG1331	Highly conserved protein containing a thioredoxin domain
Pcar_1767	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pcar_1769	COG0175	sulfate reduction
Pcar_1772	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Pcar_1775	COG2853	Lipoprotein
Pcar_1776	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Pcar_1785	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Pcar_1796	COG1215	transferase activity, transferring glycosyl groups
Pcar_1798	COG0438	transferase activity, transferring glycosyl groups
Pcar_1802	COG0110	maltose O-acetyltransferase activity
Pcar_1803	COG2244	polysaccharide biosynthetic process
Pcar_1804	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Pcar_1805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Pcar_1807	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Pcar_1811	COG4942	peptidase
Pcar_1823	COG0582	viral genome integration into host DNA
Pcar_1824	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Pcar_1827	COG0402	S-adenosylhomocysteine deaminase activity
Pcar_1828	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Pcar_1829	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Pcar_1830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Pcar_1838	COG2116	formate transmembrane transporter activity
Pcar_1839	COG0746	molybdenum cofactor guanylyltransferase activity
Pcar_1840	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Pcar_1841	COG1104	cysteine desulfurase activity
Pcar_1842	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Pcar_1842	COG4451	ribulose bisphosphate carboxylase, small
Pcar_1848	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Pcar_1850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Pcar_1851	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Pcar_1852	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Pcar_1853	COG2983	Belongs to the UPF0260 family
Pcar_1855	COG0584	glycerophosphoryl diester phosphodiesterase
Pcar_1857	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Pcar_1858	COG0482	sulfurtransferase activity
Pcar_1859	COG0822	iron-sulfur transferase activity
Pcar_1862	COG1045	serine acetyltransferase
Pcar_1864	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Pcar_1865	COG0733	neurotransmitter:sodium symporter activity
Pcar_1867	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Pcar_1868	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pcar_1869	COG0601	transmembrane transport
Pcar_1874	COG1366	Belongs to the anti-sigma-factor antagonist family
Pcar_1877	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Pcar_1878	COG0564	pseudouridine synthase activity
Pcar_1879	COG2050	protein possibly involved in aromatic compounds catabolism
Pcar_1879	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Pcar_1880	COG0776	regulation of translation
Pcar_1881	COG0616	signal peptide processing
Pcar_1882	COG2183	response to ionizing radiation
Pcar_1882	COG0539	negative regulation of cytoplasmic translation
Pcar_1883	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Pcar_1884	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Pcar_1885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Pcar_1887	COG0077	Prephenate dehydratase
Pcar_1887	COG1605	Chorismate mutase
Pcar_1888	COG0436	Aminotransferase
Pcar_1890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Pcar_1890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Pcar_1891	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Pcar_1892	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Pcar_1893	COG1862	Preprotein translocase
Pcar_1895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Pcar_1897	COG1032	radical SAM domain protein
Pcar_1898	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Pcar_1899	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Pcar_1900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Pcar_1901	COG0101	tRNA pseudouridine synthase activity
Pcar_1903	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Pcar_1904	COG0473	3-isopropylmalate dehydrogenase activity
Pcar_1905	COG0066	3-isopropylmalate dehydratase activity
Pcar_1907	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Pcar_1908	COG0688	phosphatidylethanolamine metabolic process
Pcar_1910	COG0028	Belongs to the TPP enzyme family
Pcar_1911	COG0129	dihydroxy-acid dehydratase activity
Pcar_1914	COG0750	zinc metalloprotease
Pcar_1916	COG4589	Belongs to the CDS family
Pcar_1917	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Pcar_1918	COG0233	cytoplasmic translational termination
Pcar_1919	COG0528	UMP kinase activity
Pcar_1920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Pcar_1921	COG0052	Belongs to the universal ribosomal protein uS2 family
Pcar_1924	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Pcar_1925	COG0640	Transcriptional regulator
Pcar_1927	COG1215	transferase activity, transferring glycosyl groups
Pcar_1928	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Pcar_1931	COG3716	PTS system mannose fructose sorbose family IID component
Pcar_1935	COG1660	Displays ATPase and GTPase activities
Pcar_1936	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Pcar_1938	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Pcar_1942	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Pcar_1944	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Pcar_1945	COG0504	CTP synthase activity
Pcar_1946	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Pcar_1947	COG4771	TonB-dependent receptor
Pcar_1949	COG5002	protein histidine kinase activity
Pcar_1949	COG0784	Response regulator, receiver
Pcar_1949	COG2205	protein histidine kinase activity
Pcar_1950	COG1321	iron dependent repressor
Pcar_1951	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Pcar_1953	COG0785	Cytochrome C biogenesis protein
Pcar_1957	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Pcar_1958	COG0330	HflC and HflK could
Pcar_1960	COG2204	response regulator
Pcar_1963	COG0318	PFAM AMP-dependent synthetase and ligase
Pcar_1965	COG1285	pathogenesis
Pcar_1966	COG0521	Mo-molybdopterin cofactor biosynthetic process
Pcar_1969	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Pcar_1970	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Pcar_1971	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Pcar_1971	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Pcar_1973	COG2885	chlorophyll binding
Pcar_1978	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pcar_1980	COG0612	Peptidase, M16
Pcar_1981	COG0612	Peptidase, M16
Pcar_1982	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Pcar_1983	COG0142	geranyltranstransferase activity
Pcar_1985	COG0840	transmembrane signaling receptor activity
Pcar_1986	COG1234	tRNA 3'-trailer cleavage
Pcar_1988	COG0288	reversible hydration of carbon dioxide
Pcar_1992	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Pcar_1993	COG3852	Histidine kinase
Pcar_1995	COG0305	Participates in initiation and elongation during chromosome replication
Pcar_1996	COG0359	binds to the 23S rRNA
Pcar_1998	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Pcar_1999	COG0360	Binds together with S18 to 16S ribosomal RNA
Pcar_2000	COG0012	GTP binding
Pcar_2001	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Pcar_2002	COG0193	aminoacyl-tRNA hydrolase activity
Pcar_2003	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Pcar_2004	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Pcar_2005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Pcar_2007	COG0390	transport system, permease component
Pcar_2008	COG1126	abc transporter atp-binding protein
Pcar_2009	COG1573	uracil-dna glycosylase
Pcar_2011	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Pcar_2012	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Pcar_2013	COG3481	metal-dependent phosphohydrolase, HD sub domain
Pcar_2014	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Pcar_2015	COG4191	Histidine kinase
Pcar_2016	COG0589	response to stress
Pcar_2017	COG2204	response regulator
Pcar_2018	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Pcar_2021	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Pcar_2022	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Pcar_2023	COG0105	UTP biosynthetic process
Pcar_2024	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Pcar_2025	COG2205	protein histidine kinase activity
Pcar_2026	COG1388	LysM domain
Pcar_2026	COG1376	ErfK ybiS ycfS ynhG family protein
Pcar_2029	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Pcar_2031	COG0860	N-Acetylmuramoyl-L-alanine amidase
Pcar_2036	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Pcar_2038	COG0488	(ABC) transporter
Pcar_2039	COG1530	ribonuclease E activity
Pcar_2040	COG2840	Smr protein MutS2
Pcar_2042	COG1388	LysM domain
Pcar_2042	COG0791	NLP P60 protein
Pcar_2044	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Pcar_2045	COG0784	Response regulator, receiver
Pcar_2045	COG0835	chemotaxis
Pcar_2050	COG2081	HI0933 family
Pcar_2054	COG0714	Associated with various cellular activities
Pcar_2066	COG0123	including yeast histone deacetylase and acetoin utilization protein
Pcar_2068	COG1028	Short-chain dehydrogenase reductase Sdr
Pcar_2070	COG1971	Probably functions as a manganese efflux pump
Pcar_2072	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Pcar_2072	COG0116	Belongs to the methyltransferase superfamily
Pcar_2073	COG0471	metal ion transport
Pcar_2074	COG0521	Mo-molybdopterin cofactor biosynthetic process
Pcar_2076	COG1047	Peptidyl-prolyl cis-trans
Pcar_2077	COG1047	Peptidyl-prolyl cis-trans
Pcar_2078	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Pcar_2079	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_2082	COG2409	Drug exporters of the RND superfamily
Pcar_2084	COG0725	ABC transporter, periplasmic molybdate-binding protein
Pcar_2085	COG3842	ATPase activity
Pcar_2086	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Pcar_2087	COG0725	ABC transporter, periplasmic molybdate-binding protein
Pcar_2089	COG2226	methyltransferase
Pcar_2090	COG0398	Pfam SNARE associated Golgi protein
Pcar_2097	COG1166	arginine decarboxylase activity
Pcar_2099	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Pcar_2100	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Pcar_2102	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Pcar_2106	COG0577	efflux transmembrane transporter activity
Pcar_2106	COG1136	(ABC) transporter
Pcar_2108	COG4149	molybdate abc transporter
Pcar_2109	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Pcar_2110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Pcar_2113	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Pcar_2115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Pcar_2118	COG3830	Belongs to the UPF0237 family
Pcar_2119	COG2848	UPF0210 protein
Pcar_2123	COG3177	Filamentation induced by cAMP protein fic
Pcar_2127	COG0439	Biotin carboxylase
Pcar_2128	COG0511	ligase activity, forming carbon-carbon bonds
Pcar_2129	COG0006	proline dipeptidase activity
Pcar_2132	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Pcar_2133	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Pcar_2139	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Pcar_2142	COG1131	(ABC) transporter
Pcar_2145	COG2204	response regulator
Pcar_2146	COG3852	Histidine kinase
Pcar_2147	COG1459	type II secretion system
Pcar_2149	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pcar_2150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Pcar_2151	COG0196	riboflavin kinase activity
Pcar_2152	COG0557	exoribonuclease II activity
Pcar_2160	COG2204	response regulator
Pcar_2161	COG5002	protein histidine kinase activity
Pcar_2165	COG1049	propionate catabolic process, 2-methylcitrate cycle
Pcar_2167	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Pcar_2168	COG0154	amidase activity
Pcar_2169	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Pcar_2170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Pcar_2171	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Pcar_2173	COG0488	(ABC) transporter
Pcar_2174	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Pcar_2176	COG0583	DNA-binding transcription factor activity
Pcar_2178	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Pcar_2180	COG1063	alcohol dehydrogenase
Pcar_2181	COG2814	Major facilitator Superfamily
Pcar_2182	COG0789	Transcriptional regulator
Pcar_2184	COG0738	Major facilitator superfamily
Pcar_2188	COG0710	3-dehydroquinate dehydratase activity
Pcar_2189	COG0738	Major facilitator superfamily
Pcar_2191	COG1082	Xylose isomerase domain protein TIM barrel
Pcar_2192	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Pcar_2196	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Pcar_2198	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Pcar_2199	COG1181	Belongs to the D-alanine--D-alanine ligase family
Pcar_2200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Pcar_2201	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Pcar_2202	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Pcar_2203	COG0772	Belongs to the SEDS family
Pcar_2204	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Pcar_2205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Pcar_2206	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Pcar_2207	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Pcar_2209	COG4839	cell division protein FtsL
Pcar_2210	COG0275	rRNA processing
Pcar_2211	COG2001	Belongs to the MraZ family
Pcar_2212	COG4536	flavin adenine dinucleotide binding
Pcar_2213	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Pcar_2214	COG1254	Belongs to the acylphosphatase family
Pcar_2215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Pcar_2217	COG0792	nuclease activity
Pcar_2218	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Pcar_2219	COG0335	large ribosomal subunit rRNA binding
Pcar_2220	COG4752	Belongs to the RNA methyltransferase TrmD family
Pcar_2221	COG0336	Belongs to the RNA methyltransferase TrmD family
Pcar_2222	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Pcar_2223	COG1837	Belongs to the UPF0109 family
Pcar_2224	COG0228	four-way junction DNA binding
Pcar_2225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Pcar_2227	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Pcar_2228	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Pcar_2229	COG1333	cytochrome c biogenesis protein
Pcar_2230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Pcar_2231	COG0151	Belongs to the GarS family
Pcar_2232	COG0138	bifunctional purine biosynthesis protein purh
Pcar_2234	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Pcar_2235	COG0352	thiamine-phosphate diphosphorylase activity
Pcar_2235	COG0351	phosphomethylpyrimidine kinase
Pcar_2236	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Pcar_2240	COG0133	tryptophan synthase activity
Pcar_2241	COG0159	tryptophan synthase activity
Pcar_2243	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pcar_2244	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Pcar_2245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pcar_2247	COG0534	Mate efflux family protein
Pcar_2251	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pcar_2252	COG1215	transferase activity, transferring glycosyl groups
Pcar_2253	COG0191	fructose-bisphosphate aldolase activity
Pcar_2255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Pcar_2256	COG0116	Belongs to the methyltransferase superfamily
Pcar_2259	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Pcar_2261	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Pcar_2263	COG0330	HflC and HflK could
Pcar_2274	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Pcar_2275	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pcar_2277	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Pcar_2279	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Pcar_2281	COG1323	Belongs to the UPF0348 family
Pcar_2282	COG1489	DNA binding
Pcar_2283	COG0560	Phosphoserine phosphatase
Pcar_2283	COG3830	Belongs to the UPF0237 family
Pcar_2284	COG0426	domain, Protein
Pcar_2284	COG1773	rubredoxin
Pcar_2286	COG2154	pterin-4-alpha-carbinolamine dehydratase
Pcar_2296	COG5001	Diguanylate cyclase
Pcar_2296	COG3300	MHYT domain
Pcar_2297	COG3706	GGDEF domain
Pcar_2301	COG0688	phosphatidylethanolamine metabolic process
Pcar_2303	COG0840	transmembrane signaling receptor activity
Pcar_2304	COG0671	phosphoesterase, PA-phosphatase related
Pcar_2308	COG0121	glutamine amidotransferase
Pcar_2309	COG4067	protein conserved in archaea
Pcar_2309	COG0189	ligase activity
Pcar_2310	COG0189	ligase activity
Pcar_2313	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Pcar_2315	COG0525	valine-tRNA ligase activity
Pcar_2316	COG0745	RESPONSE REGULATOR receiver
Pcar_2320	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Pcar_2321	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Pcar_2322	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Pcar_2323	COG0653	protein targeting
Pcar_2324	COG0739	heme binding
Pcar_2325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Pcar_2326	COG0497	DNA recombination
Pcar_2327	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Pcar_2328	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Pcar_2329	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pcar_2330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Pcar_2331	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Pcar_2333	COG0584	glycerophosphoryl diester phosphodiesterase
Pcar_2334	COG1494	fructose-1,6-bisphosphatase
Pcar_2335	COG0217	transcriptional regulatory protein
Pcar_2336	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Pcar_2337	COG0632	four-way junction helicase activity
Pcar_2338	COG2255	four-way junction helicase activity
Pcar_2340	COG1752	Esterase of the alpha-beta hydrolase superfamily
Pcar_2343	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Pcar_2344	COG5000	phosphorelay sensor kinase activity
Pcar_2345	COG2204	response regulator
Pcar_2346	COG1592	Rubrerythrin
Pcar_2347	COG2033	superoxide reductase activity
Pcar_2348	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Pcar_2349	COG1692	metallophosphoesterase
Pcar_2350	COG1418	mRNA catabolic process
Pcar_2351	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Pcar_2354	COG0552	protein localization to endoplasmic reticulum
Pcar_2356	COG1196	nuclear chromosome segregation
Pcar_2357	COG0564	pseudouridine synthase activity
Pcar_2359	COG2226	methyltransferase
Pcar_2362	COG1720	tRNA m6t6A37 methyltransferase activity
Pcar_2363	COG0835	chemotaxis
Pcar_2364	COG0840	transmembrane signaling receptor activity
Pcar_2367	COG0166	Belongs to the GPI family
Pcar_2368	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Pcar_2369	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Pcar_2370	COG1278	Cold shock
Pcar_2373	COG0577	efflux transmembrane transporter activity
Pcar_2373	COG1136	(ABC) transporter
Pcar_2379	COG0708	Exodeoxyribonuclease III
Pcar_2380	COG0514	ATP-dependent DNA helicase (RecQ)
Pcar_2384	COG0427	acetyl-CoA hydrolase
Pcar_2386	COG0528	UMP kinase activity
Pcar_2387	COG1509	lysine 2,3-aminomutase activity
Pcar_2390	COG0848	biopolymer transport protein
Pcar_2391	COG0811	peptide transport
Pcar_2398	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Pcar_2400	COG1691	(AIR) carboxylase
Pcar_2401	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Pcar_2402	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Pcar_2403	COG1058	Belongs to the CinA family
Pcar_2403	COG1546	Belongs to the CinA family
Pcar_2404	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Pcar_2405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Pcar_2407	COG2137	regulation of response to DNA damage stimulus
Pcar_2408	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Pcar_2411	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Pcar_2412	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Pcar_2413	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Pcar_2414	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Pcar_2415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Pcar_2416	COG1714	RDD family
Pcar_2417	COG0137	argininosuccinate synthase activity
Pcar_2418	COG0165	Argininosuccinate lyase
Pcar_2421	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pcar_2422	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Pcar_2423	COG0436	Aminotransferase
Pcar_2425	COG3385	transposase activity
Pcar_2426	COG5290	Psort location Cytoplasmic, score
Pcar_2427	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Pcar_2430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Pcar_2431	COG1606	tRNA processing
Pcar_2434	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Pcar_2435	COG0574	Belongs to the PEP-utilizing enzyme family
Pcar_2435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Pcar_2437	COG2951	lytic endotransglycosylase activity
Pcar_2438	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Pcar_2441	COG0277	FAD linked oxidase domain protein
Pcar_2443	COG0822	iron-sulfur transferase activity
Pcar_2446	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Pcar_2447	COG0427	acetyl-CoA hydrolase
Pcar_2449	COG3706	GGDEF domain
Pcar_2451	COG0668	transmembrane transport
Pcar_2454	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Pcar_2455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Pcar_2456	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Pcar_2457	COG3527	Alpha-acetolactate decarboxylase
Pcar_2460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pcar_2461	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Pcar_2462	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Pcar_2466	COG0745	RESPONSE REGULATOR receiver
Pcar_2469	COG0668	transmembrane transport
Pcar_2470	COG1643	Atp-dependent helicase
Pcar_2471	COG2195	Cleaves the N-terminal amino acid of tripeptides
Pcar_2478	COG0489	protein tyrosine kinase activity
Pcar_2481	COG1739	Uncharacterized protein family UPF0029
Pcar_2483	COG0730	response to heat
Pcar_2484	COG1408	metallophosphoesterase
Pcar_2486	COG0741	lytic transglycosylase activity
Pcar_2487	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Pcar_2489	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Pcar_2490	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Pcar_2491	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Pcar_2492	COG1115	amino acid carrier protein
Pcar_2494	COG1993	acr, cog1993
Pcar_2495	COG0430	RNA-3'-phosphate cyclase activity
Pcar_2499	COG4251	negative regulation of phosphorylation
Pcar_2499	COG5001	Diguanylate cyclase
Pcar_2499	COG2203	Gaf domain
Pcar_2499	COG3706	GGDEF domain
Pcar_2500	COG2186	Transcriptional regulator
Pcar_2505	COG1012	belongs to the aldehyde dehydrogenase family
Pcar_2508	COG1993	acr, cog1993
Pcar_2513	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Pcar_2514	COG2414	aldehyde ferredoxin oxidoreductase
Pcar_2515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_2516	COG1607	acyl-coa hydrolase
Pcar_2518	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Pcar_2519	COG0583	DNA-binding transcription factor activity
Pcar_2520	COG1509	lysine 2,3-aminomutase activity
Pcar_2527	COG1845	cytochrome c oxidase, subunit III
Pcar_2530	COG0109	protoheme IX farnesyltransferase activity
Pcar_2531	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Pcar_2532	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Pcar_2534	COG0242	peptide deformylase activity
Pcar_2536	COG0295	cytidine deaminase activity
Pcar_2540	COG0509	glycine decarboxylation via glycine cleavage system
Pcar_2542	COG0280	phosphate acetyltransferase
Pcar_2543	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Pcar_2551	COG0243	molybdopterin cofactor binding
Pcar_2551	COG3383	formate dehydrogenase (NAD+) activity
Pcar_2557	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Pcar_2563	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Pcar_2563	COG0519	Catalyzes the synthesis of GMP from XMP
Pcar_2566	COG3437	response regulator, receiver
Pcar_2567	COG2205	protein histidine kinase activity
Pcar_2572	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Pcar_2573	COG1040	competence protein
Pcar_2574	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Pcar_2576	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Pcar_2577	COG0799	negative regulation of ribosome biogenesis
Pcar_2578	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Pcar_2579	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Pcar_2580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Pcar_2581	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Pcar_2582	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Pcar_2583	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Pcar_2584	COG1530	ribonuclease E activity
Pcar_2586	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Pcar_2588	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Pcar_2589	COG0004	ammonium transporteR
Pcar_2594	COG1091	dTDP-4-dehydrorhamnose reductase activity
Pcar_2597	COG0438	transferase activity, transferring glycosyl groups
Pcar_2599	COG0069	glutamate synthase activity
Pcar_2602	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Pcar_2605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Pcar_2607	COG0840	transmembrane signaling receptor activity
Pcar_2608	COG2151	metal-sulfur cluster biosynthetic enzyme
Pcar_2611	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Pcar_2611	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Pcar_2613	COG2176	DNA-directed DNA polymerase activity
Pcar_2614	COG0024	Methionine aminopeptidase
Pcar_2617	COG2212	antiporter activity
Pcar_2619	COG0651	ATP synthesis coupled electron transport
Pcar_2620	COG1006	Multisubunit Na H antiporter MnhC subunit
Pcar_2621	COG2111	Na H antiporter
Pcar_2622	COG2111	Na H antiporter
Pcar_2622	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Pcar_2623	COG0589	response to stress
Pcar_2624	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Pcar_2625	COG2814	Major facilitator Superfamily
Pcar_2626	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Pcar_2629	COG0745	RESPONSE REGULATOR receiver
Pcar_2630	COG5002	protein histidine kinase activity
Pcar_2632	COG1671	Belongs to the UPF0178 family
Pcar_2634	COG0488	(ABC) transporter
Pcar_2639	COG0583	DNA-binding transcription factor activity
Pcar_2647	COG2996	Protein conserved in bacteria
Pcar_2651	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pcar_2653	COG1216	Glycosyl transferase, family 2
Pcar_2660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_2663	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pcar_2665	COG0445	tRNA wobble uridine modification
Pcar_2667	COG1028	Short-chain dehydrogenase reductase Sdr
Pcar_2669	COG1047	Peptidyl-prolyl cis-trans
Pcar_2671	COG2226	methyltransferase
Pcar_2677	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Pcar_2679	COG0358	DNA primase activity
Pcar_2680	COG1193	negative regulation of DNA recombination
Pcar_2681	COG1286	toxin biosynthetic process
Pcar_2683	COG0140	phosphoribosyl-ATP diphosphatase activity
Pcar_2684	COG0107	imidazoleglycerol-phosphate synthase activity
Pcar_2685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Pcar_2686	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Pcar_2687	COG0131	Imidazoleglycerol-phosphate dehydratase
Pcar_2688	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Pcar_2689	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Pcar_2690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Pcar_2691	COG2890	protein-(glutamine-N5) methyltransferase activity
Pcar_2692	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Pcar_2693	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Pcar_2694	COG0254	rRNA binding
Pcar_2695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Pcar_2698	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Pcar_2704	COG1119	ATPase activity
Pcar_2709	COG5001	Diguanylate cyclase
Pcar_2711	COG2204	response regulator
Pcar_2713	COG0598	Magnesium transport protein CorA
Pcar_2714	COG5290	Psort location Cytoplasmic, score
Pcar_2715	COG0668	transmembrane transport
Pcar_2717	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Pcar_2717	COG0321	lipoyl(octanoyl) transferase activity
Pcar_2718	COG2204	response regulator
Pcar_2719	COG3958	Transketolase
Pcar_2720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Pcar_2722	COG0646	methionine synthase
Pcar_2722	COG1410	methionine synthase
Pcar_2724	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Pcar_2742	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Pcar_2746	COG1763	Mo-molybdopterin cofactor biosynthetic process
Pcar_2748	COG4520	surface antigen
Pcar_2749	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Pcar_2750	COG1127	ABC transporter
Pcar_2753	COG0784	Response regulator, receiver
Pcar_2753	COG3437	response regulator, receiver
Pcar_2754	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Pcar_2758	COG1454	alcohol dehydrogenase
Pcar_2758	COG1012	belongs to the aldehyde dehydrogenase family
Pcar_2759	COG3852	Histidine kinase
Pcar_2760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Pcar_2762	COG0315	cyclic pyranopterin monophosphate synthase activity
Pcar_2764	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Pcar_2765	COG0277	FAD linked oxidase domain protein
Pcar_2766	COG0247	lactate metabolic process
Pcar_2768	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_2769	COG0482	sulfurtransferase activity
Pcar_2770	COG0459	protein refolding
Pcar_2771	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Pcar_2773	COG2314	TM2 domain
Pcar_2776	COG0318	PFAM AMP-dependent synthetase and ligase
Pcar_2776	COG0204	Acyl-transferase
Pcar_2777	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Pcar_2778	COG4589	Belongs to the CDS family
Pcar_2779	COG0204	Acyl-transferase
Pcar_2780	COG2267	carboxylic ester hydrolase activity
Pcar_2784	COG3842	ATPase activity
Pcar_2785	COG0861	Integral membrane protein TerC family
Pcar_2790	COG1215	transferase activity, transferring glycosyl groups
Pcar_2791	COG0726	polysaccharide deacetylase
Pcar_2791	COG1649	PFAM Uncharacterised BCR, COG1649
Pcar_2794	COG0038	chloride channel
Pcar_2795	COG0426	domain, Protein
Pcar_2797	COG1592	Rubrerythrin
Pcar_2798	COG0735	belongs to the Fur family
Pcar_2804	COG1830	Aldolase
Pcar_2806	COG1278	Cold shock
Pcar_2821	COG3501	Rhs element vgr protein
Pcar_2835	COG1690	Belongs to the RtcB family
Pcar_2836	COG0430	RNA-3'-phosphate cyclase activity
Pcar_2838	COG4650	regulator
Pcar_2843	COG1764	response to oxidative stress
Pcar_2847	COG1454	alcohol dehydrogenase
Pcar_2849	COG2204	response regulator
Pcar_2850	COG0280	phosphate acetyltransferase
Pcar_2851	COG1454	alcohol dehydrogenase
Pcar_2851	COG1012	belongs to the aldehyde dehydrogenase family
Pcar_2852	COG3426	butyrate kinase activity
Pcar_2854	COG4191	Histidine kinase
Pcar_2856	COG2391	methyltransferase activity
Pcar_2864	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Pcar_2864	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Pcar_2866	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Pcar_2867	COG3005	denitrification pathway
Pcar_2872	COG1151	hydroxylamine reductase activity
Pcar_2875	COG0577	efflux transmembrane transporter activity
Pcar_2875	COG1136	(ABC) transporter
Pcar_2877	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pcar_2878	COG1309	transcriptional regulator
Pcar_2879	COG2146	nitrite reductase [NAD(P)H] activity
Pcar_2879	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pcar_2880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Pcar_2881	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Pcar_2881	COG0116	Belongs to the methyltransferase superfamily
Pcar_2883	COG3012	SEC-C Motif Domain Protein
Pcar_2884	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pcar_2903	COG1162	GTPase activity
Pcar_2907	COG3246	L-lysine catabolic process to acetate
Pcar_2909	COG1566	PFAM secretion protein HlyD family protein
Pcar_2911	COG1289	transmembrane transporter activity
Pcar_2923	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Pcar_2925	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Pcar_2927	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Pcar_2933	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Pcar_2934	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Pcar_2938	COG0784	Response regulator, receiver
Pcar_2938	COG5002	protein histidine kinase activity
Pcar_2939	COG0288	reversible hydration of carbon dioxide
Pcar_2940	COG0567	Dehydrogenase, E1 component
Pcar_2941	COG0508	dehydrogenase complex catalyzes the overall conversion of
Pcar_2943	COG0492	ferredoxin-NADP+ reductase activity
Pcar_2944	COG0070	glutamate synthase
Pcar_2944	COG0069	glutamate synthase activity
Pcar_2944	COG0067	glutamate synthase
Pcar_2945	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Pcar_2946	COG1396	sequence-specific DNA binding
Pcar_2947	COG0546	phosphoglycolate phosphatase activity
Pcar_2948	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pcar_2950	COG0564	pseudouridine synthase activity
Pcar_2951	COG1496	oxidoreductase activity
Pcar_2954	COG0297	glycogen (starch) synthase activity
Pcar_2958	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Pcar_2959	COG0745	RESPONSE REGULATOR receiver
Pcar_2960	COG1242	4 iron, 4 sulfur cluster binding
Pcar_2963	COG1950	PFAM Membrane protein of
Pcar_2967	COG0840	transmembrane signaling receptor activity
Pcar_2969	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pcar_2970	COG4771	TonB-dependent receptor
Pcar_2972	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Pcar_2974	COG2885	chlorophyll binding
Pcar_2975	COG0823	Involved in the tonB-independent uptake of proteins
Pcar_2979	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Pcar_2981	COG1469	GTP cyclohydrolase I activity
Pcar_2982	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Pcar_2987	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Pcar_2988	COG3264	Mechanosensitive ion channel
Pcar_2988	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Pcar_2989	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Pcar_2995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Pcar_2996	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Pcar_2997	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Pcar_3004	COG1846	Transcriptional regulator
Pcar_3011	COG3848	Pyruvate phosphate dikinase
Pcar_3011	COG0574	Belongs to the PEP-utilizing enzyme family
Pcar_3014	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Pcar_3019	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Pcar_3019	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Pcar_3023	COG1451	nucleotide metabolic process
Pcar_3024	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Pcar_3027	COG2095	MarC family integral membrane protein
Pcar_3029	COG2095	MarC family integral membrane protein
Pcar_3031	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Pcar_3036	COG0546	phosphoglycolate phosphatase activity
Pcar_3045	COG5001	Diguanylate cyclase
Pcar_3045	COG4251	negative regulation of phosphorylation
Pcar_3045	COG3706	GGDEF domain
Pcar_3045	COG2203	Gaf domain
Pcar_3046	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Pcar_3058	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Pcar_3059	COG0612	Peptidase, M16
Pcar_3061	COG0113	porphobilinogen synthase activity
Pcar_3063	COG0181	hydroxymethylbilane synthase activity
Pcar_3064	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Pcar_3065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Pcar_3066	COG1648	precorrin-2 dehydrogenase activity
Pcar_3066	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Pcar_3067	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Pcar_3068	COG3118	belongs to the thioredoxin family
Pcar_3069	COG3028	Belongs to the UPF0307 family
Pcar_3070	COG1490	D-aminoacyl-tRNA deacylase activity
Pcar_3071	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Pcar_3076	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Pcar_3079	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Pcar_3080	COG2264	protein methyltransferase activity
Pcar_3082	COG5002	protein histidine kinase activity
Pcar_3083	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pcar_3084	COG1234	tRNA 3'-trailer cleavage
Pcar_3086	COG2197	response regulator
Pcar_3087	COG1556	Lactate utilization protein
Pcar_3090	COG0628	permease
Pcar_3091	COG1271	oxidase subunit
Pcar_3092	COG1294	oxidase, subunit
Pcar_3094	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pcar_3096	COG1309	transcriptional regulator
Pcar_3100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Pcar_3101	COG0617	tRNA 3'-terminal CCA addition
Pcar_3105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Pcar_3111	COG0438	transferase activity, transferring glycosyl groups
Pcar_3112	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Pcar_3113	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Pcar_3115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Pcar_3116	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Pcar_3117	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Pcar_3124	COG1595	DNA-templated transcription, initiation
Pcar_3126	COG3572	ergothioneine biosynthetic process
Pcar_3129	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Pcar_3130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Pcar_3131	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Pcar_3132	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Pcar_3133	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Pcar_3134	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Pcar_3135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Pcar_3138	COG1475	DNA binding
Pcar_3139	COG1192	Involved in chromosome partitioning
Pcar_3140	COG0357	Ribosomal RNA small subunit methyltransferase G
Pcar_3141	COG0445	tRNA wobble uridine modification
Pcar_3142	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Pcar_3143	COG0706	membrane insertase activity
Pcar_3144	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Pcar_3145	COG0594	ribonuclease P activity
Pcar_3146	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Pcar_3149	COG0535	radical SAM domain protein
Pcar_3311	COG2165	general secretion pathway protein
Pcar_3370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes