locus-tag	class	description
SYN_00001	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SYN_00005	ENOG410890F	Dynamin family
SYN_00007	ENOG4105CB5	ATP-dependent DNA helicase recG
SYN_00014	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
SYN_00016	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
SYN_00017	ENOG4105C0D	helicase
SYN_00019	ENOG4105VEQ	Cold shock protein
SYN_00021	ENOG4107RJC	Iron-containing alcohol dehydrogenase
SYN_00023	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SYN_00024	ENOG4105C19	ABC transporter
SYN_00025	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
SYN_00026	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SYN_00027	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SYN_00028	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SYN_00029	ENOG4105VN1	Heat shock protein
SYN_00034	ENOG4105CBS	Chea signal transduction histidine kinase
SYN_00036	ENOG4107V8I	Glycosyl transferases group 1
SYN_00038	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SYN_00039	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SYN_00041	ENOG4105DXN	mazG family
SYN_00042	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SYN_00045	ENOG4105K63	Thioredoxin
SYN_00047	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
SYN_00054	ENOG4108UXE	Protein tyrosine phosphatase
SYN_00056	ENOG4105CVA	phosphate
SYN_00057	ENOG4105C8U	phosphate abc transporter
SYN_00058	ENOG4105E2Z	phosphate ABC transporter (Permease
SYN_00059	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SYN_00060	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
SYN_00061	ENOG4105BZU	Histidine kinase
SYN_00062	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SYN_00063	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SYN_00064	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SYN_00066	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SYN_00067	ENOG4108VZM	50s ribosomal protein L10
SYN_00068	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
SYN_00069	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SYN_00070	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SYN_00072	ENOG41084ED	50S ribosomal protein L33
SYN_00073	ENOG4105NBF	ammecr1 domain protein
SYN_00074	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
SYN_00075	ENOG4105C8N	cysteinyl-tRNA synthetase
SYN_00077	ENOG41066FR	extracellular solute-binding protein
SYN_00079	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SYN_00081	ENOG4105D1F	ATP-binding protein
SYN_00084	ENOG4107ZS6	Flavodoxin
SYN_00088	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SYN_00090	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SYN_00091	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SYN_00092	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SYN_00093	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
SYN_00099	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SYN_00100	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
SYN_00101	ENOG4105KAV	tspo and mbr like protein
SYN_00102	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SYN_00104	ENOG4105CJR	Integral membrane protein (MviN
SYN_00105	ENOG4105VZ9	UPF0235 protein
SYN_00106	ENOG4108VIA	integral membrane protein
SYN_00107	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
SYN_00110	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SYN_00111	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
SYN_00112	ENOG4105BZU	Histidine kinase
SYN_00121	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SYN_00122	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SYN_00124	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
SYN_00125	ENOG4105CZX	twitching motility protein
SYN_00126	ENOG4105CZX	twitching motility protein
SYN_00133	ENOG4105D1S	lipid A biosynthesis
SYN_00137	ENOG4105W49	UPF0434 protein
SYN_00140	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
SYN_00143	ENOG4105KHC	sulfurtransferase
SYN_00145	ENOG41082J7	Rhodanese domain protein
SYN_00149	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
SYN_00150	ENOG4105CRE	cytochrome C
SYN_00151	ENOG4105WCA	Ferredoxin
SYN_00152	ENOG4107QIZ	NADH dehydrogenase
SYN_00153	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
SYN_00154	ENOG4105DDK	oxidoreductase, beta subunit
SYN_00155	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
SYN_00158	ENOG4107GFK	fumarate
SYN_00162	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
SYN_00163	ENOG4105C6E	dna polymerase iii
SYN_00164	ENOG4108Z6B	deaminase
SYN_00166	ENOG4105CY0	Metallo-Beta-Lactamase
SYN_00167	ENOG4105C3G	gtp-binding protein
SYN_00168	ENOG4105CHM	Aminotransferase
SYN_00169	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SYN_00178	ENOG4105C1J	atp-dependent rna helicase
SYN_00183	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
SYN_00184	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
SYN_00185	ENOG4105E02	MotA TolQ exbB proton channel
SYN_00186	ENOG4105SG9	biopolymer transport protein, ExbD
SYN_00188	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
SYN_00189	ENOG4105KCK	Peptidoglycan-associated lipoprotein
SYN_00192	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
SYN_00193	ENOG4105PXI	polysaccharide deacetylase
SYN_00194	ENOG4105CN1	protease
SYN_00197	ENOG4107QSV	RmuC domain protein
SYN_00198	ENOG4105CDV	Ompa motb domain protein
SYN_00200	ENOG4105EYH	Exonuclease
SYN_00201	ENOG4107RH8	nuclease SbcCD subunit D
SYN_00206	ENOG4107QXV	Phosphate transporter
SYN_00208	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
SYN_00209	ENOG4108JJB	ABC transporter
SYN_00210	ENOG4105VKD	bioY protein
SYN_00211	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
SYN_00212	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
SYN_00216	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
SYN_00217	ENOG4105EHG	Permease protein
SYN_00221	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
SYN_00222	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
SYN_00225	ENOG4105PGM	cation diffusion facilitator family transporter
SYN_00226	ENOG4105BZU	Histidine kinase
SYN_00229	ENOG41082AN	stage II sporulation protein
SYN_00230	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SYN_00231	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
SYN_00232	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SYN_00233	ENOG4108UJD	30S ribosomal protein S9
SYN_00234	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SYN_00241	ENOG4105CJ1	ABC, transporter
SYN_00242	ENOG4105CJ1	ABC, transporter
SYN_00243	ENOG4107QWP	ABC-2 type transporter
SYN_00244	ENOG4107QWP	ABC-2 type transporter
SYN_00245	ENOG4105D5G	Transposase
SYN_00248	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
SYN_00253	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
SYN_00259	ENOG4105DF6	Fe-S oxidoreductase
SYN_00261	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
SYN_00265	ENOG4105C26	Dehydrogenase
SYN_00268	ENOG4105X1Q	TOBE domain protein
SYN_00269	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SYN_00270	ENOG4105E0C	molybdate abc transporter
SYN_00271	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
SYN_00272	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SYN_00275	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SYN_00283	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SYN_00285	ENOG4107X8C	Efflux transporter RND family MFP subunit
SYN_00286	ENOG4105DCG	PHP domain protein
SYN_00287	ENOG4105CSM	endonuclease III
SYN_00288	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
SYN_00289	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
SYN_00291	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SYN_00294	ENOG4105D0M	Protease HtpX homolog
SYN_00295	ENOG4105CG3	alpha amylase, catalytic region
SYN_00297	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SYN_00298	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
SYN_00302	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SYN_00303	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
SYN_00304	ENOG4108JQC	penicillin-binding protein 1A
SYN_00305	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
SYN_00306	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
SYN_00307	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SYN_00308	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SYN_00309	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SYN_00310	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
SYN_00311	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SYN_00314	ENOG4107YZX	Universal stress protein
SYN_00316	ENOG4105CQB	FAD linked oxidase domain protein
SYN_00318	ENOG4105C5X	domain protein
SYN_00326	ENOG4105CWC	Acetylornithine deacetylase
SYN_00327	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
SYN_00329	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SYN_00331	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SYN_00340	ENOG4105D6J	arsenicaL-resistance protein
SYN_00347	ENOG41082YX	Transcriptional regulator, arsr family
SYN_00348	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SYN_00352	ENOG4105WCA	Ferredoxin
SYN_00359	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
SYN_00362	ENOG4108N5C	SNARE associated Golgi protein-related protein
SYN_00366	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
SYN_00368	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SYN_00369	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SYN_00370	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SYN_00371	ENOG4105CIZ	coA-substrate-specific enzyme activase
SYN_00372	ENOG41089UC	methyltransferase, type 11
SYN_00374	ENOG4108KCW	iron-sulfur cluster binding
SYN_00381	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SYN_00382	ENOG4107XWS	modD protein
SYN_00383	ENOG4108I5C	dEAD DEAH box helicase
SYN_00387	ENOG4107QXV	Phosphate transporter
SYN_00391	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
SYN_00393	ENOG41082IR	Excinuclease ABC C subunit domain protein
SYN_00394	ENOG4105VXR	cytoplasmic protein
SYN_00397	ENOG4105F5W	AtP-binding protein
SYN_00398	ENOG4105D5G	Transposase
SYN_00409	ENOG4107KIA	Virulence factor Mce family protein
SYN_00410	ENOG4105DHJ	ABC, transporter
SYN_00411	ENOG4105CY3	ABC transporter, permease
SYN_00412	ENOG4105CPF	Cell wall formation (By similarity)
SYN_00414	ENOG4108M8S	permease YjgP YjgQ family protein
SYN_00416	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
SYN_00417	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SYN_00419	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
SYN_00420	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
SYN_00421	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SYN_00423	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SYN_00424	ENOG4108IYU	L-aspartate oxidase
SYN_00426	ENOG4105C83	adenylosuccinate lyase
SYN_00429	ENOG4105CGK	Exodeoxyribonuclease III
SYN_00430	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SYN_00431	ENOG4105CBS	Chea signal transduction histidine kinase
SYN_00432	ENOG4105C8Q	Methyl-accepting chemotaxis
SYN_00433	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
SYN_00434	ENOG4105BZU	Histidine kinase
SYN_00437	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SYN_00439	ENOG4105D41	biosynthesis protein thiH
SYN_00440	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SYN_00442	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SYN_00446	ENOG4105C6T	cysteine synthase
SYN_00449	ENOG4105E4C	Lytic transglycosylase catalytic
SYN_00457	ENOG4105D7Q	type ii secretion system
SYN_00458	ENOG4107QHF	type ii secretion system protein e
SYN_00459	ENOG4108VAU	general secretion pathway protein G
SYN_00461	ENOG4105CCS	Glutamate formiminotransferase
SYN_00463	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SYN_00465	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SYN_00466	ENOG4105C5H	ABC transporter
SYN_00469	ENOG4108RAC	Rubrerythrin
SYN_00471	ENOG4105C2X	Arabinose 5-phosphate isomerase
SYN_00473	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
SYN_00474	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
SYN_00476	ENOG4105C8M	UPF0272 protein
SYN_00477	ENOG4105MRR	Transcriptional regulator (By similarity)
SYN_00481	ENOG4107QX3	carboxylase
SYN_00483	ENOG4105DVT	helicase
SYN_00494	ENOG4105CVR	type I restriction-modification system
SYN_00497	ENOG4105DZR	Type I site-specific deoxyribonuclease
SYN_00511	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
SYN_00514	ENOG4105CS1	NAD(P)H quinone oxidoreductase
SYN_00515	ENOG4105DQR	SNARE associated Golgi
SYN_00521	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
SYN_00522	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
SYN_00525	ENOG4105CPI	Metal Dependent Phosphohydrolase
SYN_00526	ENOG4108R1E	Serine threonine protein phosphatase 1
SYN_00527	ENOG4105C0H	protease
SYN_00530	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
SYN_00532	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
SYN_00533	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SYN_00534	ENOG4105DIN	metallophosphoesterase
SYN_00535	ENOG4108V0P	LemA family
SYN_00542	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SYN_00543	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SYN_00544	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SYN_00545	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SYN_00546	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SYN_00547	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SYN_00548	ENOG410835G	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SYN_00549	ENOG41084Y9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SYN_00550	ENOG4105CNI	cell division protein FtsW
SYN_00551	ENOG4105CJN	penicillin-binding protein
SYN_00554	ENOG4105DFF	Rod shape-determining protein mreb
SYN_00555	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
SYN_00558	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SYN_00559	ENOG4105MA4	psp1 domain protein
SYN_00561	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SYN_00564	ENOG4105EXW	epimerase dehydratase
SYN_00565	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
SYN_00570	ENOG4105C8Y	Acetylornithine aminotransferase
SYN_00571	ENOG4105DFA	alanine racemase domain protein
SYN_00572	ENOG4108Z03	MAF-like protein
SYN_00576	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
SYN_00578	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
SYN_00579	ENOG4105DZ0	fad dependent oxidoreductase
SYN_00581	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SYN_00583	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SYN_00584	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
SYN_00588	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
SYN_00589	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SYN_00590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_00595	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
SYN_00597	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
SYN_00598	ENOG4105CQS	hydrogenase expression formation protein HypD
SYN_00599	ENOG4107RSS	Hydrogenase accessory protein HypB
SYN_00601	ENOG4105C45	hydrogenase expression formation protein (HypE)
SYN_00604	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SYN_00606	ENOG4105BZ8	glutamate synthase
SYN_00607	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
SYN_00609	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SYN_00610	ENOG4105DKW	ABC transporter
SYN_00611	ENOG4107XM9	(LipO)protein
SYN_00615	ENOG4108Z0R	Transferase
SYN_00619	ENOG4105DB7	PHP domain protein
SYN_00621	ENOG4105E3H	phosphoglycerate mutase
SYN_00622	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
SYN_00626	ENOG4105MSY	salicylate hydroxylase
SYN_00628	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
SYN_00629	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SYN_00630	ENOG4108IEG	Formate dehydrogenase Alpha subunit
SYN_00633	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SYN_00639	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SYN_00640	ENOG4105CDU	Replicative dna helicase
SYN_00641	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
SYN_00643	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SYN_00644	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
SYN_00646	ENOG4105CD5	CoA-binding domain protein
SYN_00652	ENOG41082F9	transcriptional regulator
SYN_00654	ENOG4107RE7	phosphate butyryltransferase
SYN_00664	ENOG4105DY8	decarboxylase
SYN_00665	ENOG4105D5G	Transposase
SYN_00666	ENOG4105QNF	Outer membrane lipoprotein
SYN_00667	ENOG4105DXX	methyltransferase
SYN_00674	ENOG4105D7A	ATP-binding protein
SYN_00687	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SYN_00688	ENOG4105CGZ	zinc metallopeptidase
SYN_00689	ENOG4108R5S	membrane
SYN_00691	ENOG4105DDK	oxidoreductase, beta subunit
SYN_00692	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
SYN_00693	ENOG4105EJ5	oxidoreductase gamma subunit
SYN_00695	ENOG4108KU3	Integrase
SYN_00705	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
SYN_00706	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SYN_00708	ENOG4105VB6	UPF0109 protein
SYN_00716	ENOG4105E09	nadh pyrophosphatase
SYN_00719	ENOG4105VPX	protein, conserved in bacteria
SYN_00720	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SYN_00725	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SYN_00729	ENOG4108IYU	L-aspartate oxidase
SYN_00730	ENOG4105C34	Pseudouridine synthase
SYN_00731	ENOG4105CBX	hi0933 family
SYN_00744	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
SYN_00745	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SYN_00748	ENOG4105CD5	CoA-binding domain protein
SYN_00752	ENOG4105HBR	Rna-binding protein
SYN_00756	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SYN_00757	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SYN_00758	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SYN_00759	ENOG4105KTH	gatB Yqey
SYN_00760	ENOG4107YU2	histidine triad (hIT) protein
SYN_00761	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SYN_00765	ENOG4105K5M	30s ribosomal protein S16
SYN_00766	ENOG4105VB6	UPF0109 protein
SYN_00767	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SYN_00768	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SYN_00769	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
SYN_00770	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SYN_00771	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SYN_00772	ENOG41082RQ	UPF0102 protein
SYN_00774	ENOG4105CJ1	ABC, transporter
SYN_00776	ENOG4105BZU	Histidine kinase
SYN_00779	ENOG4108QV3	biosynthesis protein
SYN_00783	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SYN_00785	ENOG4108IV0	ABC, transporter
SYN_00786	ENOG4105C0Z	ABC transporter
SYN_00787	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SYN_00788	ENOG4105C32	Amino acid ABC transporter (Permease)
SYN_00789	ENOG4105CP9	extracellular ligand-binding receptor
SYN_00791	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SYN_00792	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SYN_00794	ENOG4105N82	Endonuclease
SYN_00795	ENOG4105D4P	Coproporphyrinogen iii oxidase
SYN_00796	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SYN_00797	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SYN_00798	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SYN_00806	ENOG4105Q1T	In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination
SYN_00814	ENOG4106855	Competence protein
SYN_00817	ENOG4105E2K	Glycosyl transferase (Group 1
SYN_00818	ENOG4105CPK	Glycosyl transferase (Group 1
SYN_00822	ENOG4105K64	Glycosyl transferase, family 2
SYN_00826	ENOG4108D32	Methyltransferase
SYN_00827	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SYN_00829	ENOG4105CKK	Glycosyl transferase, family 2
SYN_00842	ENOG4105EWA	aspartate glutamate uridylate kinase
SYN_00846	ENOG4107QPK	)-transporter
SYN_00848	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
SYN_00852	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
SYN_00853	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SYN_00854	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SYN_00856	ENOG4105CND	Glycosyl transferase, family 2
SYN_00858	ENOG4107BJW	polysaccharide deacetylase
SYN_00864	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SYN_00867	ENOG4105C3Q	Glycosyl transferase, family 2
SYN_00868	ENOG4106J7S	Glycosyl transferase, family 2
SYN_00869	ENOG4105D1Z	hydroxypyruvate reductase
SYN_00870	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
SYN_00875	ENOG4105ETX	regulatoR
SYN_00878	ENOG41061AI	Protein of unknown function (DUF2905)
SYN_00879	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
SYN_00881	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
SYN_00885	ENOG4105VB9	50S ribosomal protein l28
SYN_00887	ENOG4105CTQ	phosphohexokinase
SYN_00888	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
SYN_00889	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SYN_00890	ENOG4105D6E	homoserine dehydrogenase
SYN_00891	ENOG4105E3H	phosphoglycerate mutase
SYN_00892	ENOG41082UD	thioesterase Superfamily protein
SYN_00894	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SYN_00896	ENOG4105C0B	DNA polymerase III (alpha subunit)
SYN_00897	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SYN_00899	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
SYN_00901	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SYN_00902	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
SYN_00903	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SYN_00904	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SYN_00905	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SYN_00906	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
SYN_00908	ENOG4105CHM	Aminotransferase
SYN_00909	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SYN_00910	ENOG4106H78	methyltransferase
SYN_00911	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SYN_00912	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SYN_00913	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
SYN_00914	ENOG41072GX	Peptidase M22 Glycoprotease
SYN_00915	ENOG4105DZP	Membrane-associated zinc metalloprotease
SYN_00916	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
SYN_00917	ENOG4105KNE	Phosphatidate cytidylyltransferase
SYN_00918	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SYN_00919	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SYN_00920	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
SYN_00921	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SYN_00922	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SYN_00924	ENOG4105CRK	lysyL-tRNA synthetase
SYN_00926	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
SYN_00934	ENOG4105CYC	Transferase
SYN_00935	ENOG4105CYC	Transferase
SYN_00939	ENOG4105CI3	gtp-binding protein typa
SYN_00941	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
SYN_00943	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
SYN_00944	ENOG4105MS2	ribosomal subunit Interface protein
SYN_00945	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SYN_00946	ENOG4108IUZ	ABC transporter
SYN_00950	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
SYN_00952	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SYN_00954	ENOG4105DSE	periplasmic solute binding protein
SYN_00955	ENOG4105FDK	ABC transporter
SYN_00959	ENOG4107RD7	Flagellar Motor Protein, MotA
SYN_00960	ENOG4105ER2	Ompa motb domain protein
SYN_00962	ENOG4108VYJ	response regulator receiver protein
SYN_00963	ENOG4105CBS	Chea signal transduction histidine kinase
SYN_00964	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SYN_00965	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SYN_00967	ENOG4108VYJ	response regulator receiver protein
SYN_00969	ENOG4108094	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SYN_00970	ENOG4105BZU	Histidine kinase
SYN_00971	ENOG4105C8Q	Methyl-accepting chemotaxis
SYN_00974	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SYN_00975	ENOG4108V3W	Chemotaxis protein, CheW
SYN_00977	ENOG4105C8Q	Methyl-accepting chemotaxis
SYN_00978	ENOG4105C8Q	Methyl-accepting chemotaxis
SYN_00979	ENOG4105DCF	alanine dehydrogenase
SYN_00981	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SYN_00982	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
SYN_00983	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SYN_00984	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
SYN_00985	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SYN_00986	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SYN_00987	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
SYN_00988	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SYN_00989	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
SYN_00990	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SYN_00991	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SYN_00992	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
SYN_00993	ENOG41082SA	50s ribosomal protein l29
SYN_00994	ENOG4105C75	arginyL-tRNA synthetase
SYN_01000	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SYN_01002	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SYN_01003	ENOG4108UVJ	appr-1-p processing domain protein
SYN_01006	ENOG41060K3	Methyltransferase
SYN_01012	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
SYN_01013	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SYN_01014	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SYN_01015	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
SYN_01016	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SYN_01017	ENOG4105DGU	Histone deacetylase
SYN_01020	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SYN_01022	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SYN_01023	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SYN_01029	ENOG4105DR4	Methyltransferase
SYN_01032	ENOG4105CE9	30S ribosomal protein S2
SYN_01033	ENOG4105NXH	GreA GreB family elongation factor
SYN_01035	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
SYN_01036	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SYN_01037	ENOG4105C7H	Helicase, RecD TraA family
SYN_01040	ENOG4107QSA	Oxaloacetate decarboxylase
SYN_01041	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SYN_01045	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
SYN_01048	ENOG4105GAV	receptor
SYN_01050	ENOG4108BSC	Methyltransferase
SYN_01051	ENOG4105S10	periplasmic binding protein
SYN_01052	ENOG4105M15	transport protein ExbD
SYN_01053	ENOG4105M8K	biopolymer transport protein
SYN_01054	ENOG4105E0A	ABC, transporter
SYN_01055	ENOG4105EHG	Permease protein
SYN_01056	ENOG4105S10	periplasmic binding protein
SYN_01057	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
SYN_01064	ENOG4105UYK	outer membrane protein a
SYN_01066	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
SYN_01071	ENOG4107QI6	Cysteine desulfurase
SYN_01072	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
SYN_01073	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
SYN_01077	ENOG4105BZU	Histidine kinase
SYN_01078	ENOG4105M3Z	response regulator
SYN_01079	ENOG4105BZU	Histidine kinase
SYN_01080	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
SYN_01083	ENOG4105C5I	Dehydrogenase
SYN_01084	ENOG4105EU2	peptidase U61 LD-carboxypeptidase A
SYN_01085	ENOG4108JIC	nucleoside recognition domain protein
SYN_01091	ENOG4105CZN	Potassium uptake protein
SYN_01092	ENOG4107ZYR	domain protein
SYN_01093	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01094	ENOG4105BZU	Histidine kinase
SYN_01095	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
SYN_01096	ENOG4105ESV	Glycosyl transferase, family 4
SYN_01101	ENOG4105BZF	Glycosyl transferase (Group 1
SYN_01107	ENOG4105K64	Glycosyl transferase, family 2
SYN_01108	ENOG41088M2	Glycosyl transferase family 2
SYN_01111	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
SYN_01124	ENOG4107QQG	Dehydrogenase
SYN_01128	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SYN_01129	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SYN_01130	ENOG4108IAJ	Nad-dependent epimerase dehydratase
SYN_01139	ENOG4108GH0	ATP-binding protein yghT
SYN_01141	ENOG4105CGN	Glycosyl transferase (Group 1
SYN_01142	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
SYN_01146	ENOG4105C1G	acyl-Coa dehydrogenase
SYN_01147	ENOG4105CYW	agmatinase
SYN_01149	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SYN_01156	ENOG4105DAN	ATP-dependent protease
SYN_01158	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
SYN_01164	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SYN_01166	ENOG4105DF6	Fe-S oxidoreductase
SYN_01173	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SYN_01175	ENOG4108R96	Methyltransferase, YaeB family
SYN_01181	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01182	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
SYN_01184	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
SYN_01185	ENOG4105D1F	ATP-binding protein
SYN_01187	ENOG4105D1F	ATP-binding protein
SYN_01195	ENOG4105DZS	Phenylacetate-CoA ligase
SYN_01200	ENOG4105TMB	Formate nitrite transporter
SYN_01205	ENOG4105DAY	polysaccharide export protein
SYN_01210	ENOG4105CKM	Branched-chain carboxylic acid kinase
SYN_01211	ENOG4107RE7	phosphate butyryltransferase
SYN_01213	ENOG4105C5B	carbamate kinase
SYN_01215	ENOG4108JPW	Aminotransferase
SYN_01218	ENOG4105EU0	Major facilitator Superfamily
SYN_01223	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SYN_01225	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
SYN_01228	ENOG4105K70	DNA-binding protein
SYN_01229	ENOG4107ZS6	Flavodoxin
SYN_01234	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SYN_01236	ENOG4105C8Q	Methyl-accepting chemotaxis
SYN_01241	ENOG41080XP	Cbs domain
SYN_01242	ENOG4105D82	Glutamate dehydrogenase
SYN_01248	ENOG4105KPY	Small multidrug resistance protein
SYN_01250	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SYN_01251	ENOG4107QI6	Cysteine desulfurase
SYN_01253	ENOG4105C6T	cysteine synthase
SYN_01256	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SYN_01257	ENOG4105D7W	serine acetyltransferase
SYN_01258	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
SYN_01259	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SYN_01260	ENOG4105DWV	Homoserine O-trans-acetylase
SYN_01261	ENOG4105E0X	reductase
SYN_01262	ENOG4105CY3	ABC transporter, permease
SYN_01263	ENOG4105DHJ	ABC, transporter
SYN_01266	ENOG410903C	(LipO)protein
SYN_01273	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
SYN_01274	ENOG4105CNU	cell division protein FtsK
SYN_01278	ENOG4105DSJ	YicC domain protein
SYN_01279	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SYN_01280	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SYN_01281	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SYN_01282	ENOG4105C2N	RNA methyltransferase TrmH family group 3
SYN_01287	ENOG4105C5X	domain protein
SYN_01292	ENOG4105ETX	regulatoR
SYN_01293	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
SYN_01294	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
SYN_01297	ENOG4105VEQ	Cold shock protein
SYN_01299	ENOG4105CQC	Prephenate dehydratase
SYN_01300	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
SYN_01305	ENOG4105N1F	Hnh endonuclease
SYN_01308	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
SYN_01309	ENOG4105E39	Enoyl-CoA hydratase
SYN_01310	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
SYN_01313	ENOG4108RAV	Conserved protein
SYN_01314	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SYN_01320	ENOG4106851	UPF0270 protein
SYN_01324	ENOG4105BZU	Histidine kinase
SYN_01325	ENOG4105D5G	Transposase
SYN_01335	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
SYN_01336	ENOG4105C25	Primosomal protein n'
SYN_01337	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
SYN_01339	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
SYN_01342	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SYN_01347	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
SYN_01348	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SYN_01350	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SYN_01351	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SYN_01352	ENOG4105K46	50S ribosomal protein l27
SYN_01353	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
SYN_01359	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
SYN_01363	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SYN_01364	ENOG4105BZU	Histidine kinase
SYN_01365	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
SYN_01370	ENOG4107QHI	-hydrogenase
SYN_01372	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SYN_01373	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01375	ENOG4105K78	MarR family Transcriptional regulator
SYN_01377	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
SYN_01378	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SYN_01383	ENOG4105VCQ	rubredoxin
SYN_01385	ENOG4105VCQ	rubredoxin
SYN_01390	ENOG4105CDH	Citrulline--aspartate ligase
SYN_01394	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
SYN_01395	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SYN_01396	ENOG4105BZA	Phosphoglycerate kinase
SYN_01398	ENOG4107QX3	carboxylase
SYN_01399	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SYN_01400	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SYN_01401	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
SYN_01402	ENOG4105CTP	PilT protein domain protein
SYN_01404	ENOG4107QHF	type ii secretion system protein e
SYN_01405	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SYN_01406	ENOG41082T9	Membrane
SYN_01407	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
SYN_01408	ENOG4107TT5	NLP P60 protein
SYN_01409	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SYN_01411	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SYN_01413	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
SYN_01421	ENOG4105CK2	sodium dicarboxylate symporter
SYN_01423	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
SYN_01425	ENOG4105D05	Receptor
SYN_01426	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
SYN_01427	ENOG4105EHG	Permease protein
SYN_01428	ENOG4105CPI	Metal Dependent Phosphohydrolase
SYN_01431	ENOG4105D9Q	decarboxylase (Beta subunit)
SYN_01437	ENOG4105VEQ	Cold shock protein
SYN_01440	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SYN_01441	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SYN_01444	ENOG4108RWN	rrna methyltransferase
SYN_01445	ENOG4105VF7	tolerance protein
SYN_01447	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SYN_01448	ENOG4105C7Z	Conserved Protein
SYN_01451	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SYN_01453	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SYN_01454	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SYN_01456	ENOG4107QWP	ABC-2 type transporter
SYN_01457	ENOG4107QWP	ABC-2 type transporter
SYN_01458	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
SYN_01459	ENOG4105CJ1	ABC, transporter
SYN_01460	ENOG4105CJ1	ABC, transporter
SYN_01461	ENOG4105D0S	secretion protein (HlyD
SYN_01465	ENOG4105BZU	Histidine kinase
SYN_01466	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01467	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
SYN_01468	ENOG4108ZC9	flagellar basal-body rod protein flgc
SYN_01469	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
SYN_01470	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
SYN_01471	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SYN_01478	ENOG4108JYZ	YitT family
SYN_01481	ENOG4105F8J	Adenylate Guanylate cyclase
SYN_01482	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SYN_01483	ENOG4105CPF	Cell wall formation (By similarity)
SYN_01486	ENOG4105K4H	Nlp p60 protein
SYN_01510	ENOG4105VG9	Plasmid stabilization system
SYN_01517	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SYN_01518	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SYN_01520	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
SYN_01521	ENOG4105DWF	phosphomethylpyrimidine kinase
SYN_01522	ENOG4105FJ0	thiamine
SYN_01524	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SYN_01525	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SYN_01527	ENOG4105C3F	Signal peptidase i
SYN_01529	ENOG4105CJW	magnesium transporter
SYN_01532	ENOG4105CXT	aspartate transcarbamylase
SYN_01533	ENOG4105CD3	dihydroorotase
SYN_01534	ENOG4105CJW	magnesium transporter
SYN_01535	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
SYN_01536	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
SYN_01537	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
SYN_01539	ENOG4107YZX	Universal stress protein
SYN_01548	ENOG4105GVR	general secretion pathway protein D
SYN_01549	ENOG4107QHF	type ii secretion system protein e
SYN_01550	ENOG4105D7Q	type ii secretion system
SYN_01551	ENOG4108VAU	general secretion pathway protein G
SYN_01552	ENOG4105VWV	general secretion pathway protein h
SYN_01560	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SYN_01561	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
SYN_01563	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
SYN_01564	ENOG4105BZ1	(ABC) transporter
SYN_01565	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SYN_01566	ENOG4105D9R	oxidoreductase
SYN_01567	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SYN_01568	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SYN_01572	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SYN_01574	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SYN_01577	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
SYN_01580	ENOG4107R3E	Citrate transporter
SYN_01590	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
SYN_01591	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SYN_01592	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SYN_01593	ENOG4105VPB	50S ribosomal protein L30
SYN_01594	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SYN_01595	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SYN_01597	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SYN_01598	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SYN_01599	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SYN_01600	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SYN_01601	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SYN_01603	ENOG4108ZT0	50S ribosomal protein l17
SYN_01605	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SYN_01607	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
SYN_01609	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
SYN_01610	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SYN_01611	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SYN_01624	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
SYN_01625	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SYN_01626	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SYN_01627	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SYN_01628	ENOG4105C5F	glutamine synthetase
SYN_01629	ENOG4105BZ8	glutamate synthase
SYN_01630	ENOG4105CBC	glutamate synthase
SYN_01633	ENOG4108JUA	Transcriptional regulator
SYN_01635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01636	ENOG4105BZU	Histidine kinase
SYN_01638	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
SYN_01639	ENOG4107QPK	)-transporter
SYN_01640	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
SYN_01643	ENOG4105DF6	Fe-S oxidoreductase
SYN_01647	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
SYN_01648	ENOG4107QIZ	NADH dehydrogenase
SYN_01649	ENOG4108IEH	NADH dehydrogenase subunit g
SYN_01650	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SYN_01651	ENOG4105N5T	Radical SAM Protein
SYN_01652	ENOG4107RAQ	aminopeptidase
SYN_01653	ENOG4105E39	Enoyl-CoA hydratase
SYN_01654	ENOG4105EC5	6-oxocyclohex-1-ene-1-carbonyl-CoA
SYN_01659	ENOG4105DGN	Electron transport complex
SYN_01661	ENOG4105DZB	Electron transport complex
SYN_01662	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
SYN_01663	ENOG4105D6A	Electron transport complex
SYN_01664	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
SYN_01666	ENOG4105CJ1	ABC, transporter
SYN_01668	ENOG41081YB	ApbE family
SYN_01675	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
SYN_01676	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SYN_01677	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SYN_01680	ENOG4105CHR	reductase
SYN_01681	ENOG4105CHU	acetyl-coa acetyltransferase
SYN_01683	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SYN_01684	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SYN_01685	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
SYN_01686	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
SYN_01693	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SYN_01694	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SYN_01695	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SYN_01696	ENOG4105CHR	reductase
SYN_01697	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
SYN_01698	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SYN_01700	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SYN_01701	ENOG4105BZU	Histidine kinase
SYN_01702	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01706	ENOG4105C0H	protease
SYN_01708	ENOG4105C01	Dihydroxy-acid dehydratase
SYN_01709	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
SYN_01711	ENOG4105C7K	acetolactate synthase
SYN_01713	ENOG4105C7K	acetolactate synthase
SYN_01717	ENOG4105C22	threonyL-tRNA synthetase
SYN_01718	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SYN_01719	ENOG4105VJV	50s ribosomal protein L35
SYN_01720	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SYN_01721	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SYN_01723	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SYN_01724	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SYN_01725	ENOG4105WJX	transcriptional regulator MERR family
SYN_01727	ENOG4105F3R	pts system mannose fructose sorbose family iid
SYN_01728	ENOG41080Z8	PHOSPHOCARRIER protein
SYN_01729	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
SYN_01733	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SYN_01734	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SYN_01735	ENOG4105HHA	aminodeoxychorismate lyase
SYN_01736	ENOG4108V6E	Cell division protein mraZ
SYN_01737	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SYN_01738	ENOG41068JM	cell division protein, FtsL
SYN_01739	ENOG4105CJN	penicillin-binding protein
SYN_01740	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SYN_01742	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
SYN_01743	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
SYN_01744	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SYN_01746	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
SYN_01747	ENOG4105DFU	Cell wall formation (By similarity)
SYN_01748	ENOG4105D4A	Cell wall formation (By similarity)
SYN_01761	ENOG4105X0D	Fimbrial protein
SYN_01763	ENOG4105DJV	ribulose-phosphate 3-epimerase
SYN_01766	ENOG4108URH	decarboxylase
SYN_01767	ENOG4105K5G	30S ribosomal protein S21
SYN_01768	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
SYN_01772	ENOG4105E4G	Type IV pilus
SYN_01779	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
SYN_01780	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SYN_01782	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SYN_01783	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SYN_01784	ENOG4107XI1	DHH family
SYN_01785	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
SYN_01786	ENOG4105W7A	Protein of unknown function (DUF503)
SYN_01787	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
SYN_01789	ENOG4105CHV	Transcription elongation factor NusA
SYN_01790	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SYN_01792	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SYN_01793	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SYN_01794	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SYN_01795	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SYN_01796	ENOG41082DI	50s ribosomal protein l31
SYN_01799	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
SYN_01801	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
SYN_01802	ENOG4105CSA	Coproporphyrinogen iii oxidase
SYN_01803	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SYN_01804	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SYN_01808	ENOG4105BZU	Histidine kinase
SYN_01809	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01814	ENOG4105KME	endoribonuclease L-psp
SYN_01819	ENOG4105E7D	Protein of unknown function (DUF3375)
SYN_01824	ENOG4105D8D	Type III
SYN_01827	ENOG4105C0D	helicase
SYN_01849	ENOG4105C4R	Atp-dependent dna helicase
SYN_01852	ENOG4105C0D	helicase
SYN_01855	ENOG4105D29	Helix-turn-helix type 11 domain protein
SYN_01899	ENOG4105F5W	AtP-binding protein
SYN_01900	ENOG4106IJN	integrase catalytic domain-containing protein
SYN_01901	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SYN_01903	ENOG4105CKB	glycosidase
SYN_01904	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SYN_01906	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SYN_01907	ENOG4105VN1	Heat shock protein
SYN_01908	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SYN_01909	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SYN_01918	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SYN_01919	ENOG4108JUA	Transcriptional regulator
SYN_01921	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_01923	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
SYN_01924	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SYN_01926	ENOG4105DU1	integral membrane protein, terc
SYN_01929	ENOG4105C1J	atp-dependent rna helicase
SYN_01933	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
SYN_01934	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SYN_01935	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
SYN_01936	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SYN_01937	ENOG4105E2X	shikimate dehydrogenase
SYN_01938	ENOG41084GS	Type I DHQase
SYN_01939	ENOG4105D49	3-dehydroquinate synthase
SYN_01940	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
SYN_01941	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SYN_01943	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SYN_01944	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SYN_01945	ENOG4107QYG	anthranilate phosphoribosyltransferase
SYN_01946	ENOG4105DDQ	anthranilate synthase
SYN_01947	ENOG4105CRQ	synthase (Component I)
SYN_01948	ENOG4105DTN	riboflavin biosynthesis protein ribF
SYN_01949	ENOG4105CD5	CoA-binding domain protein
SYN_01953	ENOG4105WH1	Two component transcriptional regulator luxr family
SYN_01954	ENOG4105BZU	Histidine kinase
SYN_01960	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SYN_01964	ENOG4108Z43	UPF0250 protein
SYN_01966	ENOG4105C87	Aminotransferase class I and II
SYN_01967	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
SYN_01969	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SYN_01974	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SYN_01975	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SYN_01976	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SYN_01977	ENOG4108VUY	thioesterase Superfamily protein
SYN_01978	ENOG4105C5H	ABC transporter
SYN_01980	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
SYN_01981	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SYN_01983	ENOG4105CFG	Acts as a chaperone (By similarity)
SYN_01984	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
SYN_01988	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SYN_01990	ENOG4105D1H	recombination factor protein RarA
SYN_01991	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SYN_01993	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
SYN_01994	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SYN_01995	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SYN_01998	ENOG4108JQC	penicillin-binding protein 1A
SYN_02002	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SYN_02003	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
SYN_02005	ENOG4105BZU	Histidine kinase
SYN_02006	ENOG4105EUB	pirin domain protein
SYN_02008	ENOG4105CKU	formyltetrahydrofolate synthetase
SYN_02012	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SYN_02019	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SYN_02023	ENOG4105C0H	protease
SYN_02024	ENOG4105CN1	protease
SYN_02026	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SYN_02027	ENOG4105KC9	Modulates RecA activity (By similarity)
SYN_02028	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SYN_02029	ENOG4105M7V	2'-5' rna ligase
SYN_02030	ENOG4107TH8	cina domain protein
SYN_02037	ENOG4105EMN	RNA polymerase sigma factor
SYN_02039	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SYN_02048	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SYN_02049	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SYN_02050	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SYN_02051	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SYN_02053	ENOG4107QJE	Chromosome Partitioning Protein
SYN_02054	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SYN_02056	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SYN_02057	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
SYN_02058	ENOG4105HEE	Binding Domain protein
SYN_02064	ENOG4105CMI	transporter
SYN_02065	ENOG4105CJ1	ABC, transporter
SYN_02066	ENOG4105D0S	secretion protein (HlyD
SYN_02068	ENOG4105DY2	Paraquat-inducible protein b
SYN_02070	ENOG4105CY3	ABC transporter, permease
SYN_02071	ENOG4105C0D	helicase
SYN_02073	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SYN_02074	ENOG4105BZS	acriflavin resistance protein
SYN_02075	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SYN_02076	ENOG41082JN	Transcriptional regulator
SYN_02078	ENOG4105PW4	Sugar fermentation stimulation protein homolog
SYN_02080	ENOG4107QYA	phosphate
SYN_02081	ENOG4107RE7	phosphate butyryltransferase
SYN_02085	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SYN_02089	ENOG4105K63	Thioredoxin
SYN_02096	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SYN_02097	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SYN_02101	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
SYN_02103	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SYN_02104	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SYN_02105	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SYN_02108	ENOG4108RZE	Tetr family transcriptional regulator
SYN_02110	ENOG4105CDV	Ompa motb domain protein
SYN_02112	ENOG4105CD5	CoA-binding domain protein
SYN_02114	ENOG4105KWG	Pfam:DUF1696
SYN_02118	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
SYN_02121	ENOG4105DUM	transcriptional regulator, lysR family
SYN_02122	ENOG4105D98	threonine synthase
SYN_02123	ENOG4105VCQ	rubredoxin
SYN_02126	ENOG4105C3J	Cysteine desulfurase
SYN_02127	ENOG4105CHR	reductase
SYN_02128	ENOG4105C1G	acyl-Coa dehydrogenase
SYN_02130	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
SYN_02133	ENOG4105D41	biosynthesis protein thiH
SYN_02134	ENOG4107QW8	radical SAM domain protein
SYN_02137	ENOG4108IEG	Formate dehydrogenase Alpha subunit
SYN_02138	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SYN_02140	ENOG4105FCD	Major Facilitator
SYN_02145	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SYN_02149	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SYN_02151	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SYN_02152	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SYN_02153	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SYN_02154	ENOG4105CAS	nag kinase
SYN_02155	ENOG4105C8Y	Acetylornithine aminotransferase
SYN_02156	ENOG4105DBV	ornithine carbamoyltransferase
SYN_02157	ENOG4105CDH	Citrulline--aspartate ligase
SYN_02158	ENOG4105CH7	arginosuccinase
SYN_02160	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
SYN_02161	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SYN_02162	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SYN_02163	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SYN_02165	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SYN_02166	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SYN_02170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SYN_02172	ENOG4108JQ7	(ABC) transporter
SYN_02173	ENOG4105DHZ	alpha beta
SYN_02176	ENOG4105CCT	upf0313 protein
SYN_02177	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
SYN_02178	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
SYN_02184	ENOG4108PXI	ErfK YbiS YcfS YnhG
SYN_02186	ENOG4105CSA	Coproporphyrinogen iii oxidase
SYN_02187	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SYN_02188	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SYN_02189	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
SYN_02190	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
SYN_02191	ENOG4105EM7	Selenocysteine-specific translation elongation factor
SYN_02194	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SYN_02195	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
SYN_02196	ENOG4105C03	ribonuclease
SYN_02197	ENOG4105II7	pyrroline-5-carboxylate reductase
SYN_02199	ENOG4105ERG	peptidase m48, ste24p
SYN_02201	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
SYN_02208	ENOG4105CE1	Ferrous iron transport protein b
SYN_02211	ENOG4105BZU	Histidine kinase
SYN_02212	ENOG4108YZA	Nitrogen regulatory protein pii
SYN_02214	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_02215	ENOG4105BZU	Histidine kinase
SYN_02220	ENOG4107SHJ	sulfite reductase subunit b
SYN_02222	ENOG4105DPX	Hydrogenase, large subunit
SYN_02224	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SYN_02225	ENOG4105C8U	phosphate abc transporter
SYN_02226	ENOG4105CVA	phosphate
SYN_02227	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SYN_02229	ENOG4105VXN	addiction module toxin, RelE StbE family
SYN_02232	ENOG4107NFR	Fructose-1,6-bisphosphatase
SYN_02239	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
SYN_02256	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
SYN_02257	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SYN_02260	ENOG4105DZ1	carboxypeptidase
SYN_02261	ENOG4105C2M	dna polymerase I
SYN_02264	ENOG4105CGH	5'-nucleotidase
SYN_02265	ENOG4108UMR	transcriptional regulator AsnC family
SYN_02266	ENOG4108BB0	Elp3
SYN_02267	ENOG4105D52	delta-aminolevulinic acid dehydratase
SYN_02268	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
SYN_02273	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
SYN_02274	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
SYN_02276	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SYN_02277	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SYN_02278	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SYN_02298	ENOG4105EFV	Major head subunit
SYN_02301	ENOG4107XYH	virion morphogenesis protein
SYN_02303	ENOG4105QIB	mu-like prophage Flumu protein gp29
SYN_02342	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
SYN_02351	ENOG4105C59	p-type ATPase
SYN_02354	ENOG410841Q	phosphoesterase PA-phosphatase related protein
SYN_02356	ENOG41083UI	stage II sporulation protein
SYN_02357	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
SYN_02359	ENOG4107SGM	protein serine threonine phosphatase
SYN_02360	ENOG4105CYC	Transferase
SYN_02361	ENOG4108ESY	Metal dependent phosphohydrolase
SYN_02362	ENOG4105KNH	Nucleic acid-binding protein
SYN_02363	ENOG41082GS	50S ribosomal protein L32
SYN_02364	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SYN_02365	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SYN_02366	ENOG4108YZG	isomerase
SYN_02367	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SYN_02369	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
SYN_02370	ENOG4108R6K	riboflavin synthase, subunit alpha
SYN_02371	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
SYN_02372	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SYN_02373	ENOG4105M7K	Involved in the transcription termination process (By similarity)
SYN_02374	ENOG4105C8T	Leucyl-tRNA synthetase
SYN_02376	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
SYN_02377	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
SYN_02379	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
SYN_02380	ENOG4105BZU	Histidine kinase
SYN_02382	ENOG4107R37	Glutamate dehydrogenase
SYN_02391	ENOG4105CKK	Glycosyl transferase, family 2
SYN_02394	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SYN_02396	ENOG4105CH6	catalase
SYN_02398	ENOG4105E4F	Isochorismate synthase
SYN_02399	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
SYN_02403	ENOG4105CFU	surface antigen
SYN_02416	ENOG4105U5Y	Transcriptional regulator
SYN_02421	ENOG4105DF6	Fe-S oxidoreductase
SYN_02423	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
SYN_02425	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
SYN_02426	ENOG4107QIZ	NADH dehydrogenase
SYN_02427	ENOG4107QHI	-hydrogenase
SYN_02430	ENOG4105C1J	atp-dependent rna helicase
SYN_02436	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SYN_02437	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SYN_02439	ENOG4107QNG	Phosphoribosylglycinamide synthetase
SYN_02440	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SYN_02442	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SYN_02443	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SYN_02446	ENOG4105D5U	fad dependent oxidoreductase
SYN_02447	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
SYN_02450	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SYN_02452	ENOG41083MR	nifu domain-containing protein
SYN_02454	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
SYN_02455	ENOG4105DX0	Hemolysin A
SYN_02456	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
SYN_02458	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SYN_02459	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SYN_02473	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
SYN_02481	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SYN_02486	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SYN_02487	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
SYN_02492	ENOG4105VCQ	rubredoxin
SYN_02494	ENOG4105WKW	Pfam:DUF1458
SYN_02498	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
SYN_02499	ENOG4105DQU	oxidoreductase, subunit beta
SYN_02501	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SYN_02502	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SYN_02520	ENOG4105K4P	CoA-binding domain protein
SYN_02523	ENOG4108RAC	Rubrerythrin
SYN_02525	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SYN_02526	ENOG4105DG4	malate L-lactate dehydrogenase
SYN_02529	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SYN_02530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_02531	ENOG4105BZU	Histidine kinase
SYN_02534	ENOG4105CUT	histidyl-tRNA synthetase
SYN_02535	ENOG4105C9M	aspartyl-trna synthetase
SYN_02536	ENOG4107SDT	Homocitrate synthase
SYN_02538	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SYN_02539	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
SYN_02541	ENOG4107S2Z	UPF0761 membrane protein
SYN_02543	ENOG4105BZU	Histidine kinase
SYN_02544	ENOG4107YZX	Universal stress protein
SYN_02551	ENOG4107QYX	exodeoxyribonuclease v alpha
SYN_02552	ENOG4107QKA	exodeoxyribonuclease V beta
SYN_02553	ENOG4105DSY	exodeoxyribonuclease V, gamma
SYN_02557	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SYN_02559	ENOG4108RAC	Rubrerythrin
SYN_02561	ENOG4105CDV	Ompa motb domain protein
SYN_02563	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
SYN_02564	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SYN_02565	ENOG4108TVJ	Nitroreductase
SYN_02566	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SYN_02570	ENOG4105BZU	Histidine kinase
SYN_02572	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SYN_02583	ENOG4105DEU	major facilitator superfamily
SYN_02584	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SYN_02586	ENOG4105C1G	acyl-Coa dehydrogenase
SYN_02587	ENOG4105C1G	acyl-Coa dehydrogenase
SYN_02588	ENOG4105WH1	Two component transcriptional regulator luxr family
SYN_02590	ENOG4108I0Q	anthranilate phosphoribosyltransferase
SYN_02591	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SYN_02592	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SYN_02594	ENOG4105CYC	Transferase
SYN_02597	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
SYN_02599	ENOG4105C4R	Atp-dependent dna helicase
SYN_02602	ENOG4105C9M	aspartyl-trna synthetase
SYN_02603	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SYN_02604	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SYN_02607	ENOG4105CD5	CoA-binding domain protein
SYN_02609	ENOG4105CD5	CoA-binding domain protein
SYN_02614	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
SYN_02616	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
SYN_02617	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
SYN_02618	ENOG4105C1A	potassium transporter peripheral membrane
SYN_02621	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
SYN_02623	ENOG4105DR5	peptidase
SYN_02626	ENOG41088YS	Glycosyl transferase (Group 1
SYN_02627	ENOG4108K4C	ec 3.1.3.12
SYN_02628	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
SYN_02629	ENOG4105D8X	mechanosensitive ion channel
SYN_02632	ENOG4105CVE	Lytic murein transglycosylase
SYN_02635	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SYN_02636	ENOG4105BZJ	Electron transfer flavoprotein
SYN_02637	ENOG4105C10	Electron transfer flavoprotein
SYN_02638	ENOG4105DF6	Fe-S oxidoreductase
SYN_02640	ENOG4105CEY	Amp-dependent synthetase and ligase
SYN_02641	ENOG4105E3H	phosphoglycerate mutase
SYN_02642	ENOG4105CHU	acetyl-coa acetyltransferase
SYN_02643	ENOG4105CEY	Amp-dependent synthetase and ligase
SYN_02647	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SYN_02648	ENOG4105FAW	cDP-glucose 4,6-dehydratase
SYN_02649	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
SYN_02650	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SYN_02652	ENOG4108SMP	Nad-dependent epimerase dehydratase
SYN_02656	ENOG4105EY8	ABC transporter
SYN_02659	ENOG4105K64	Glycosyl transferase, family 2
SYN_02660	ENOG4105K64	Glycosyl transferase, family 2
SYN_02665	ENOG4105K64	Glycosyl transferase, family 2
SYN_02667	ENOG4105CG5	Glycosyl transferase (Group 1
SYN_02669	ENOG4105ESV	Glycosyl transferase, family 4
SYN_02671	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SYN_02675	ENOG4107QQG	Dehydrogenase
SYN_02678	ENOG4105CAQ	asparagine synthetase
SYN_02683	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
SYN_02686	ENOG4105D3Q	Sugar transferase
SYN_02687	ENOG4108UW5	maltose o-acetyltransferase
SYN_02688	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SYN_02690	ENOG4105E3R	(LipO)protein
SYN_02699	ENOG4105CHM	Aminotransferase
SYN_02700	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
SYN_02701	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SYN_02702	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SYN_02704	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
SYN_02705	ENOG4107QMS	site-determining protein
SYN_02706	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
SYN_02707	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SYN_02708	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SYN_02709	ENOG4105C5X	domain protein
SYN_02710	ENOG4105C8V	SAICAR synthetase
SYN_02711	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SYN_02713	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SYN_02714	ENOG4105ES5	Histidine kinase
SYN_02721	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SYN_02722	ENOG4105BZU	Histidine kinase
SYN_02739	ENOG41065RQ	ADP-ribosylation crystallin J1
SYN_02754	ENOG4105ESI	atpase involved in dna repair
SYN_02755	ENOG4105CB5	ATP-dependent DNA helicase recG
SYN_02758	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
SYN_02759	ENOG4108JA2	transcriptioN-repair coupling factor
SYN_02760	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
SYN_02761	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
SYN_02763	ENOG4105D7N	magnesium and cobalt transport protein CorA
SYN_02766	ENOG4107R7Y	intracellular protease Pfpi family
SYN_02767	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SYN_02768	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
SYN_02769	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SYN_02770	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SYN_02772	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SYN_02773	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
SYN_02775	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SYN_02776	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SYN_02777	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SYN_02779	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SYN_02780	ENOG4105K8N	protein family UPF0079, ATPase
SYN_02781	ENOG4105CFH	Aspartokinase
SYN_02782	ENOG4105KQC	Competence protein
SYN_02783	ENOG4105E4C	Lytic transglycosylase catalytic
SYN_02784	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
SYN_02785	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SYN_02786	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SYN_02787	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SYN_02789	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
SYN_02790	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SYN_02791	ENOG4105E9H	Lytic Murein transglycosylase
SYN_02792	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SYN_02793	ENOG4105CTJ	Metal Dependent Phosphohydrolase
SYN_02795	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
SYN_02798	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SYN_02799	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
SYN_02800	ENOG4105E4C	Lytic transglycosylase catalytic
SYN_02801	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SYN_02803	ENOG4107TVC	Glycosyl transferase, family 2
SYN_02806	ENOG4105MQ3	flagellar protein FliS
SYN_02809	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
SYN_02810	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
SYN_02811	ENOG4105DTJ	flagellar hook-associated protein
SYN_02812	ENOG4105E1Q	flagellar hook-associated protein
SYN_02816	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SYN_02817	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SYN_02818	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
SYN_02819	ENOG4105CGA	flagellar basal-body rod protein FlgG
SYN_02820	ENOG4108KPB	Flagellar basal-body rod protein FlgF
SYN_02821	ENOG4105D00	flagellar biosynthetic protein flhB
SYN_02827	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SYN_02828	ENOG4107R21	site-determining protein
SYN_02829	ENOG4105FZW	flagellar biosynthesis regulator FlhF
SYN_02830	ENOG4105D7B	Flagellar biosynthesis protein flha
SYN_02832	ENOG4105D00	flagellar biosynthetic protein flhB
SYN_02833	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
SYN_02834	ENOG4105VS8	Flagellar biosynthetic protein fliq
SYN_02835	ENOG4105CN7	Flagellar biosynthetic protein FliP
SYN_02836	ENOG4105DD5	Flagellar motor switch protein
SYN_02837	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SYN_02839	ENOG4105BZE	flagellar hook protein, FlgE
SYN_02845	ENOG4108IQ3	PTS system
SYN_02847	ENOG410801F	ribosomal-protein-alanine acetyltransferase
SYN_02848	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
SYN_02850	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
SYN_02851	ENOG4105C5X	domain protein
SYN_02852	ENOG4105CQ7	ATP-dependent helicase
SYN_02853	ENOG4107T0K	Adenylate cyclase
SYN_02856	ENOG4105FE9	pseudouridine synthase
SYN_02857	ENOG4105C31	Tryptophanyl-tRNA synthetase
SYN_02862	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SYN_02863	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SYN_02866	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SYN_02867	ENOG4105DIW	FeS assembly protein SUFB
SYN_02873	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SYN_02876	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SYN_02878	ENOG4105CD5	CoA-binding domain protein
SYN_02883	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
SYN_02885	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
SYN_02886	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SYN_02888	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SYN_02889	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
SYN_02892	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
SYN_02903	ENOG4108S0S	Nucleotidyl transferase
SYN_02907	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
SYN_02908	ENOG4105ENA	helicase
SYN_02917	ENOG4105DZ0	fad dependent oxidoreductase
SYN_02922	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
SYN_02923	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SYN_02926	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SYN_02930	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SYN_02931	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
SYN_02935	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SYN_02936	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
SYN_02937	ENOG4105CHM	Aminotransferase
SYN_02943	ENOG4105IPI	Membrane
SYN_02946	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SYN_02948	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SYN_02950	ENOG4107QP8	phosphohexose isomerase
SYN_02951	ENOG4105CHC	glucokinase (EC 2.7.1.2)
SYN_02953	ENOG4105CTQ	phosphohexokinase
SYN_02954	ENOG4107RCW	fructose-bisphosphate aldolase
SYN_02956	ENOG4108JUA	Transcriptional regulator
SYN_02959	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
SYN_02961	ENOG4105CHW	UPF0052 protein
SYN_02965	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SYN_02970	ENOG4105WPN	DNA integration recombination invertion protein
SYN_02971	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SYN_02972	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SYN_02973	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
SYN_02974	ENOG4105CDY	transcriptional regulatory protein
SYN_02977	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SYN_02978	ENOG4105D48	metallophosphoesterase
SYN_02979	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SYN_02981	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
SYN_02983	ENOG4105CP7	Triose-phosphate isomerase
SYN_02985	ENOG4107QMP	dna polymerase iii subunits gamma and tau
SYN_02987	ENOG4105D5G	Transposase
SYN_02993	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
SYN_03003	ENOG4105K3G	Periplasmic Protein
SYN_03005	ENOG4105EN6	Membrane
SYN_03008	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
SYN_03026	ENOG4105C8N	cysteinyl-tRNA synthetase
SYN_03031	ENOG4108QV3	biosynthesis protein
SYN_03032	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
SYN_03045	ENOG410812A	polypeptide-transport-associated domain protein, FtsQ-type
SYN_03046	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SYN_03059	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SYN_03061	ENOG4106855	Competence protein
SYN_03065	ENOG4105D5G	Transposase
SYN_03076	ENOG4105E39	Enoyl-CoA hydratase
SYN_03078	ENOG4107QXV	Phosphate transporter
SYN_03090	ENOG4105CKM	Branched-chain carboxylic acid kinase
SYN_03092	ENOG4105D5G	Transposase
SYN_03096	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYN_03102	ENOG4105D5G	Transposase
SYN_03108	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
SYN_03109	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SYN_03110	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SYN_03115	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYN_03119	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
SYN_03127	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
SYN_03128	ENOG4105CEY	Amp-dependent synthetase and ligase
SYN_03131	ENOG4108V1U	phospholipid-binding protein
SYN_03141	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
SYN_03145	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
SYN_03150	ENOG41062IR	nudix hydrolase
SYN_03153	ENOG4105C0P	Mg chelatase subunit ChlI
SYN_03154	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SYN_03155	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SYN_03162	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
SYN_03163	ENOG4105DQU	oxidoreductase, subunit beta
SYN_03174	ENOG4105D5G	Transposase
SYN_03192	ENOG4105C0B	DNA polymerase III (alpha subunit)
SYN_03195	ENOG4105ERG	peptidase m48, ste24p
SYN_03196	ENOG4105CAT	Cytidine monophosphate kinase
SYN_03197	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SYN_03198	ENOG4105D07	Signal peptide peptidase, SppA
SYN_03199	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SYN_03200	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SYN_03201	ENOG4105W5Q	DNA repair protein (RadC
SYN_03204	ENOG4105F8V	Hydrolase, tatD family
SYN_03213	ENOG4105DF6	Fe-S oxidoreductase
SYN_03223	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SYN_03227	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SYN_03230	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
SYN_03234	ENOG4106HK8	GPR1 FUN34 yaaH family protein
SYN_03250	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
SYN_03252	ENOG4105EAH	synthase
SYN_03254	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SYN_03255	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SYN_03256	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SYN_03257	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SYN_03272	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SYN_03279	ENOG4105E2Z	phosphate ABC transporter (Permease
SYN_03311	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SYN_03313	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
SYN_03314	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SYN_03315	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SYN_03316	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
SYN_03385	ENOG4105CRE	cytochrome C
SYN_03523	ENOG4105F1A	Pyruvate formate-lyase
SYN_03543	ENOG4105K59	histidine triad (HIT) protein
SYN_03606	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SYN_03628	ENOG4105D0M	Protease HtpX homolog
SYN_03643	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SYN_03680	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYN_03698	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SYN_03702	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
SYN_03707	ENOG4105X5Z	General secretion pathway protein I
SYN_03718	ENOG4105Q1T	In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination
SYN_03778	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
SYN_03787	ENOG4107ZT5	Thiol disulfide interchange protein
SYN_03790	ENOG4105CP7	Triose-phosphate isomerase