locus-tag	class	description
A7K99_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A7K99_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A7K99_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A7K99_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A7K99_00025	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A7K99_00025	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A7K99_00030	ENOG4105E89	ABC transporter
A7K99_00035	ENOG410667J	hydrolase
A7K99_00055	ENOG4105D99	atp gtp-binding protein
A7K99_00060	ENOG4105R2A	(LipO)protein
A7K99_00065	ENOG4108ZNX	Heat shock protein
A7K99_00070	ENOG4108594	Permease of the drug metabolite transporter
A7K99_00075	ENOG4105JKW	Valine--pyruvate aminotransferase
A7K99_00085	ENOG4108M60	Transcriptional regulator
A7K99_00090	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A7K99_00095	ENOG4108PM0	it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity)
A7K99_00100	ENOG4106CVF	DNA replication protein
A7K99_00105	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A7K99_00110	ENOG4105KZK	Tautomerase pptA
A7K99_00115	ENOG4108UZX	fmn reductase
A7K99_00120	ENOG4105WPN	DNA integration recombination invertion protein
A7K99_00125	ENOG4105D52	delta-aminolevulinic acid dehydratase
A7K99_00130	ENOG4105CSH	Transporter
A7K99_00135	ENOG4108W1V	Lipoprotein
A7K99_00140	ENOG4105EX9	Membrane
A7K99_00145	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A7K99_00150	ENOG4107FS9	Membrane
A7K99_00160	ENOG4105MG3	Membrane
A7K99_00165	ENOG4106H78	methyltransferase
A7K99_00170	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A7K99_00175	ENOG4105CAK	Cell division ATP-binding protein ftsE
A7K99_00180	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A7K99_00190	ENOG4105U59	-acetyltransferase
A7K99_00200	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
A7K99_00205	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
A7K99_00210	ENOG4108IJ9	(ABC) transporter
A7K99_00215	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
A7K99_00225	ENOG4105C2I	pirin domain protein
A7K99_00230	ENOG4105DIQ	Transcriptional regulator
A7K99_00235	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A7K99_00240	ENOG4105C6Z	Gluconate
A7K99_00245	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
A7K99_00250	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A7K99_00255	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A7K99_00260	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A7K99_00270	ENOG4105E98	transcriptional regulator DeoR family
A7K99_00275	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
A7K99_00280	ENOG4105MJ2	Competence protein
A7K99_00285	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A7K99_00300	ENOG4105BZM	domain protein
A7K99_00305	ENOG4108RRZ	Transcription elongation factor GreB
A7K99_00310	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A7K99_00315	ENOG4105E0F	Histidine kinase
A7K99_00320	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A7K99_00325	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A7K99_00330	ENOG4105VEJ	Heat shock protein
A7K99_00335	ENOG4105DQY	intracellular growth attenuator
A7K99_00340	ENOG4107RK2	ADP-ribose diphosphatase NudE
A7K99_00345	ENOG4108JQC	penicillin-binding protein 1A
A7K99_00375	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A7K99_00380	ENOG4105D49	3-dehydroquinate synthase
A7K99_00385	ENOG4105EGB	membrane protein DamX
A7K99_00385	ENOG4105EGB	membrane protein DamX
A7K99_00395	ENOG4105DJV	ribulose-phosphate 3-epimerase
A7K99_00400	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A7K99_00405	ENOG4105C31	Tryptophanyl-tRNA synthetase
A7K99_00410	ENOG4106DTQ	Protein TsgA homolog
A7K99_00415	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A7K99_00425	ENOG4105C8Y	Acetylornithine aminotransferase
A7K99_00430	ENOG410613R	integral membrane protein, YccS YhfK family
A7K99_00440	ENOG4108UKZ	OsmC family
A7K99_00445	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
A7K99_00455	ENOG4105DNZ	Alpha Beta Hydrolase
A7K99_00465	ENOG4105C5H	ABC transporter
A7K99_00470	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A7K99_00475	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A7K99_00480	ENOG4105VKU	nucleicacid-binding protein
A7K99_00485	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A7K99_00490	ENOG4105VRX	Protein slyX homolog
A7K99_00495	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A7K99_00500	ENOG4105WWK	YheO domain protein
A7K99_00505	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A7K99_00510	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A7K99_00520	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A7K99_00530	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A7K99_00535	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A7K99_00555	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A7K99_00560	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A7K99_00575	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A7K99_00580	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A7K99_00585	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A7K99_00590	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A7K99_00595	ENOG41083MP	50s ribosomal protein l29
A7K99_00600	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A7K99_00605	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A7K99_00610	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A7K99_00615	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7K99_00625	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A7K99_00630	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A7K99_00635	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A7K99_00640	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A7K99_00645	ENOG4105VPB	50S ribosomal protein L30
A7K99_00650	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A7K99_00655	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A7K99_00665	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A7K99_00670	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A7K99_00675	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A7K99_00680	ENOG4108ZT0	50S ribosomal protein l17
A7K99_00685	ENOG4105VTS	DnaJ-like, subfamily C
A7K99_00690	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
A7K99_00695	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A7K99_00700	ENOG4105C1A	potassium transporter peripheral membrane
A7K99_00705	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A7K99_00710	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A7K99_00720	ENOG4105C79	DNA protecting protein DprA
A7K99_00730	ENOG4108WI1	Dna topoisomerase
A7K99_00735	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A7K99_00740	ENOG4105E2X	shikimate dehydrogenase
A7K99_00745	ENOG4105SG3	Protein of unknown function (DUF1488)
A7K99_00750	ENOG4108Z0R	Transferase
A7K99_00785	ENOG4105C5W	Aldolase
A7K99_00795	ENOG4107XBN	GntR Family Transcriptional Regulator
A7K99_00805	ENOG4105BZW	Glycerate kinase
A7K99_00810	ENOG4105DJ2	Major Facilitator Superfamily
A7K99_00815	ENOG4105R1U	AraC Family Transcriptional Regulator
A7K99_00845	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A7K99_00850	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A7K99_00855	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A7K99_00860	ENOG4108IA2	Sodium pantothenate symporter
A7K99_00865	ENOG4105RG0	Membrane
A7K99_00870	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A7K99_00875	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A7K99_00880	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A7K99_00885	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A7K99_00895	ENOG41062P1	Diguanylate cyclase phosphodiesterase
A7K99_00900	ENOG4105DFF	Rod shape-determining protein mreb
A7K99_00905	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A7K99_00910	ENOG4105VQ7	Rod shape-determining protein MreD
A7K99_00920	ENOG4105C03	ribonuclease
A7K99_00925	ENOG4105QD6	exported protein
A7K99_00930	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A7K99_00935	ENOG4105CR8	Transcriptional regulator
A7K99_00940	ENOG4105ZQC	membrane protein AaeX
A7K99_00945	ENOG4105Y49	secretion protein, HlyD family
A7K99_00950	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
A7K99_00960	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A7K99_00965	ENOG4105C0H	protease
A7K99_00970	ENOG4105C0H	protease
A7K99_00975	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
A7K99_00980	ENOG4105D6Z	AFG1 family ATPase
A7K99_00985	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A7K99_00990	ENOG4108UJD	30S ribosomal protein S9
A7K99_00995	ENOG4107MKT	Stringent starvation protein a
A7K99_01000	ENOG4105KB2	stringent starvation protein b
A7K99_01005	ENOG4105BZ8	glutamate synthase
A7K99_01010	ENOG4105CBC	glutamate synthase
A7K99_01015	ENOG4105BZU	Histidine kinase
A7K99_01030	ENOG41080Z8	PHOSPHOCARRIER protein
A7K99_01035	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A7K99_01040	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
A7K99_01045	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A7K99_01050	ENOG4108IUZ	ABC transporter
A7K99_01055	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
A7K99_01060	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
A7K99_01070	ENOG4105C2X	Arabinose 5-phosphate isomerase
A7K99_01075	ENOG4105FEU	K -dependent Na -Ca exchanger
A7K99_01080	ENOG4105DHJ	ABC, transporter
A7K99_01085	ENOG4105CY3	ABC transporter, permease
A7K99_01090	ENOG4107PE3	Mammalian cell entry related domain protein
A7K99_01095	ENOG4105E3I	toluene tolerance
A7K99_01100	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
A7K99_01105	ENOG4105VFK	BolA family
A7K99_01110	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A7K99_01115	ENOG4105HVQ	Regulatory factor of maltose metabolism
A7K99_01125	ENOG4105EAH	synthase
A7K99_01130	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A7K99_01135	ENOG4105K46	50S ribosomal protein l27
A7K99_01140	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7K99_01145	ENOG4105KA0	thioesterase Superfamily protein
A7K99_01150	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A7K99_01155	ENOG4105WQI	isochorismatase
A7K99_01160	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A7K99_01165	ENOG4105E4F	Isochorismate synthase
A7K99_01170	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
A7K99_01175	ENOG4105DQ5	transport system permease protein
A7K99_01180	ENOG4105TVJ	transport system, permease
A7K99_01185	ENOG4105E0A	ABC, transporter
A7K99_01190	ENOG4105C0W	non-ribosomal peptide synthetase
A7K99_01200	ENOG4105E93	esterase
A7K99_01205	ENOG4107RNH	Outer membrane receptor FepA
A7K99_01210	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
A7K99_01215	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A7K99_01220	ENOG4105HBR	Rna-binding protein
A7K99_01225	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A7K99_01230	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A7K99_01235	ENOG4105EEI	dihydropteroate synthase
A7K99_01240	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A7K99_01260	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A7K99_01265	ENOG4105CHV	Transcription elongation factor NusA
A7K99_01270	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A7K99_01275	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A7K99_01280	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A7K99_01285	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A7K99_01290	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A7K99_01300	ENOG4105C1J	atp-dependent rna helicase
A7K99_01305	ENOG4105DEN	Luciferase family
A7K99_01310	ENOG4106RZ4	Peptidase U32
A7K99_01315	ENOG4105CFP	Peptidase U32
A7K99_01320	ENOG4105XPQ	lipid carrier protein
A7K99_01325	ENOG4108YYD	acetyltransferase
A7K99_01330	ENOG41082IR	Excinuclease ABC C subunit domain protein
A7K99_01335	ENOG4108ZPB	UPF0306 protein
A7K99_01345	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
A7K99_01350	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
A7K99_01355	ENOG4105KME	endoribonuclease L-psp
A7K99_01370	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A7K99_01375	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A7K99_01380	ENOG4105DBV	ornithine carbamoyltransferase
A7K99_01390	ENOG4105CEU	Arginine dihydrolase
A7K99_01400	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
A7K99_01405	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
A7K99_01410	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
A7K99_01425	ENOG4105CDA	abc transporter atp-binding protein
A7K99_01430	ENOG4105E5Q	amino acid AbC transporter
A7K99_01435	ENOG4107R0W	ABC transporter
A7K99_01445	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A7K99_01455	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A7K99_01470	ENOG4105EAD	ABC transporter
A7K99_01475	ENOG4105E5Q	amino acid AbC transporter
A7K99_01480	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A7K99_01490	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A7K99_01495	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A7K99_01500	ENOG4105MYG	DNA polymerase iii, chi subunit
A7K99_01505	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A7K99_01510	ENOG4108M8S	permease YjgP YjgQ family protein
A7K99_01515	ENOG4108K5H	permease YjgP YjgQ family protein
A7K99_01520	ENOG4108BMY	protease
A7K99_01525	ENOG4106BRA	Membrane
A7K99_01530	ENOG4107RSM	transcriptional regulator
A7K99_01540	ENOG4105CSH	Transporter
A7K99_01545	ENOG4105D7A	ATP-binding protein
A7K99_01570	ENOG4105RI1	glycoprotein receptor
A7K99_01690	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
A7K99_01695	ENOG4105QUH	Domain of unknown function (DUF2088)
A7K99_01700	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
A7K99_01705	ENOG4105C8M	UPF0272 protein
A7K99_01715	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
A7K99_01725	ENOG4105UEI	Transcriptional Regulator AraC Family
A7K99_01750	ENOG4107QNK	)-transporter
A7K99_01760	ENOG41066U0	
A7K99_01805	ENOG4105CBP	Major Facilitator
A7K99_01860	ENOG4108JU7	Transcriptional regulator
A7K99_01865	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A7K99_01890	ENOG4108UMI	ABC transporter, permease
A7K99_01900	ENOG41079KZ	Major Facilitator Superfamily
A7K99_01905	ENOG4107T8P	acyl-Coa dehydrogenase
A7K99_01910	ENOG4107T8P	acyl-Coa dehydrogenase
A7K99_01915	ENOG4107T8P	acyl-Coa dehydrogenase
A7K99_01925	ENOG4107T8P	acyl-Coa dehydrogenase
A7K99_01930	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
A7K99_01935	ENOG4105CNT	hydrolase family 2
A7K99_01940	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_01955	ENOG41090HR	transcriptional regulator
A7K99_01980	ENOG4105EAB	amino acid AbC transporter
A7K99_01985	ENOG4105E5Q	amino acid AbC transporter
A7K99_01995	ENOG4107PP3	Acetylornithine deacetylase
A7K99_02000	ENOG4107S8C	mandelate racemase muconate lactonizing
A7K99_02005	ENOG4105ENR	peptidase, M24
A7K99_02010	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A7K99_02015	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A7K99_02040	ENOG4108HRK	Histidine kinase
A7K99_02045	ENOG4108NEV	two component transcriptional regulator, LytTR family
A7K99_02050	ENOG4105CKI	cobalamin synthesis protein
A7K99_02055	ENOG4105VCD	cytoplasmic protein
A7K99_02060	ENOG4105D22	carbon starvation protein
A7K99_02065	ENOG4105CTS	PTS system mannitol-specific
A7K99_02070	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
A7K99_02075	ENOG4105E61	Mannitol repressor protein
A7K99_02080	ENOG4105H38	Membrane
A7K99_02085	ENOG4105CKT	filamentous hemagglutinin
A7K99_02100	ENOG4106B0W	Curli production assembly transport component CsgG
A7K99_02110	ENOG4107Y60	(LipO)protein
A7K99_02125	ENOG4105C32	Amino acid ABC transporter (Permease)
A7K99_02135	ENOG4105C2J	ABC transporter
A7K99_02140	ENOG4108IV0	ABC, transporter
A7K99_02160	ENOG4105C54	Major Facilitator superfamily
A7K99_02165	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
A7K99_02170	ENOG4105DQ4	alcohol dehydrogenase
A7K99_02175	ENOG4107GFK	fumarate
A7K99_02195	ENOG4107H6U	ABC transporter
A7K99_02200	ENOG4105C3U	ABC transporter
A7K99_02205	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A7K99_02210	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A7K99_02215	ENOG4105DEF	Extracellular solute-binding protein, family 5
A7K99_02220	ENOG4108UQS	dipeptidase
A7K99_02230	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A7K99_02240	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A7K99_02245	ENOG4105BZS	acriflavin resistance protein
A7K99_02250	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A7K99_02255	ENOG4105KD7	acetyltransferase
A7K99_02265	ENOG4105D1S	lipid A biosynthesis
A7K99_02275	ENOG4108YYH	Nadph-dependent fmn reductase
A7K99_02285	ENOG4108RVA	ribokinase
A7K99_02290	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A7K99_02295	ENOG4108R66	Conserved Protein
A7K99_02300	ENOG4108I5G	Major Facilitator superfamily
A7K99_02305	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A7K99_02310	ENOG4105EDR	glucose galactose transporter
A7K99_02315	ENOG4108KPW	sugar kinase
A7K99_02325	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_02330	ENOG4105EMF	GntR family transcriptional regulator
A7K99_02335	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
A7K99_02340	ENOG4108RTU	Aldolase
A7K99_02345	ENOG4105CXK	mandelate racemase muconate lactonizing
A7K99_02355	ENOG4105C5I	Dehydrogenase
A7K99_02360	ENOG4105VNT	transposase (IS4 family) protein
A7K99_02385	ENOG4106QJH	hemin transport protein
A7K99_02390	ENOG4107R4I	Periplasmic binding protein
A7K99_02395	ENOG4105EHG	Permease protein
A7K99_02400	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A7K99_02405	ENOG4105CSR	polyphosphate kinase 2
A7K99_02410	ENOG4105CJ3	phosphate transporter
A7K99_02415	ENOG4108KSB	HipA-like N-terminal domain
A7K99_02420	ENOG4105MHH	HipA N-terminal domain protein
A7K99_02435	ENOG4105EE0	oxidoreductase
A7K99_02440	ENOG4107R11	Transcriptional regulator
A7K99_02455	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A7K99_02465	ENOG4105DEN	Luciferase family
A7K99_02490	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A7K99_02500	ENOG4105DEF	Extracellular solute-binding protein, family 5
A7K99_02505	ENOG4108JQ6	ABC transporter
A7K99_02510	ENOG4105D44	asparaginase
A7K99_02515	ENOG4105CHR	reductase
A7K99_02520	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A7K99_02525	ENOG4107PP3	Acetylornithine deacetylase
A7K99_02530	ENOG4107FB0	transcriptional regulator DeoR family
A7K99_02560	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
A7K99_02565	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
A7K99_02570	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
A7K99_02575	ENOG4105H6Q	decarboxylase
A7K99_02580	ENOG4105CMG	Carbohydrate kinase
A7K99_02590	ENOG4108R66	Conserved Protein
A7K99_02600	ENOG4105J4Q	Transcriptional regulator
A7K99_02610	ENOG4105CT4	transporter
A7K99_02625	ENOG4105CWB	LysR family transcriptional Regulator
A7K99_02635	ENOG4108YYH	Nadph-dependent fmn reductase
A7K99_02655	ENOG4105E5Q	amino acid AbC transporter
A7K99_02680	ENOG4107XBN	GntR Family Transcriptional Regulator
A7K99_02685	ENOG4105CDA	abc transporter atp-binding protein
A7K99_02690	ENOG4105DRP	amino acid AbC transporter
A7K99_02695	ENOG4105E5Q	amino acid AbC transporter
A7K99_02700	ENOG4106TNF	Periplasmic binding protein
A7K99_02705	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A7K99_02725	ENOG4105DQR	SNARE associated Golgi
A7K99_02755	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A7K99_02765	ENOG4108QBX	(LipO)protein
A7K99_02770	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A7K99_02775	ENOG4105CZE	histidine utilization repressor
A7K99_02780	ENOG41090B9	response to stress
A7K99_02785	ENOG4105C84	Histidine ammonia-lyase
A7K99_02795	ENOG4105E90	ABC transporter
A7K99_02800	ENOG4105E90	ABC transporter
A7K99_02805	ENOG4108IJ8	ABC transporter
A7K99_02810	ENOG4105CGP	Urocanate hydratase
A7K99_02815	ENOG4105ETS	cytosine purines uracil thiamine allantoin
A7K99_02830	ENOG4105CPQ	Dehydrogenase
A7K99_02835	ENOG4105C6Z	Gluconate
A7K99_02840	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A7K99_02880	ENOG4105F38	ABC transporter, permease
A7K99_02895	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_02900	ENOG4106NZI	LysR family Transcriptional regulator
A7K99_02905	ENOG4105C01	Dihydroxy-acid dehydratase
A7K99_02910	ENOG4105DG4	malate L-lactate dehydrogenase
A7K99_02915	ENOG4105CZJ	Aldehyde dehydrogenase
A7K99_02930	ENOG41080HI	glycine oxidase
A7K99_02940	ENOG4107QTZ	amino acid
A7K99_02945	ENOG4105DFI	Membrane
A7K99_02960	ENOG4107R7A	Allophanate hydrolase subunit 2
A7K99_02965	ENOG4105E7W	lamb ycsf family protein
A7K99_02970	ENOG4105CHM	Aminotransferase
A7K99_02995	ENOG4105E5Q	amino acid AbC transporter
A7K99_03000	ENOG4105DRP	amino acid AbC transporter
A7K99_03010	ENOG4106RHG	Yeca family
A7K99_03015	ENOG4107W52	maltose operon periplasmic protein
A7K99_03020	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
A7K99_03035	ENOG4107FKK	extracellular solute-binding protein family 1
A7K99_03040	ENOG4105D56	permease protein
A7K99_03045	ENOG4105EG2	ABC transporter, permease
A7K99_03065	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
A7K99_03070	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A7K99_03075	ENOG41061ZR	Transcriptional regulator
A7K99_03080	ENOG4105R0I	Feruloyl esterase
A7K99_03105	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A7K99_03110	ENOG4105T38	integral membrane protein
A7K99_03115	ENOG4105H3G	oxidoreductase
A7K99_03130	ENOG4105CDA	abc transporter atp-binding protein
A7K99_03145	ENOG4105G63	Type III effector Hrp-dependent
A7K99_03165	ENOG4105FB2	class II Aldolase
A7K99_03170	ENOG4105MVE	transcriptional regulator
A7K99_03175	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A7K99_03180	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A7K99_03185	ENOG4105VCC	30S ribosomal protein S21
A7K99_03200	ENOG4107ZVW	dihydroneopterin aldolase
A7K99_03205	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A7K99_03210	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A7K99_03215	ENOG4106MWK	domain protein
A7K99_03220	ENOG4105I7R	Adenylate cyclase
A7K99_03225	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A7K99_03235	ENOG4105W0Z	cytoplasmic protein
A7K99_03240	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A7K99_03245	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
A7K99_03250	ENOG4106032	Glutathionylspermidine synthase
A7K99_03255	ENOG4105F1G	UPF0441 protein
A7K99_03265	ENOG41087AY	ADP-Ribose pyrophosphatase
A7K99_03270	ENOG4108SX3	cytoplasmic protein
A7K99_03275	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A7K99_03280	ENOG4105IPS	esterase
A7K99_03285	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A7K99_03290	ENOG4108UZ3	Transporter
A7K99_03295	ENOG4107RNH	Outer membrane receptor FepA
A7K99_03300	ENOG4105NIV	Esterase
A7K99_03305	ENOG4108JCI	Transcriptional regulator
A7K99_03320	ENOG4105W7K	Transcriptional regulator
A7K99_03325	ENOG4105NF4	modulator of drug activity
A7K99_03330	ENOG4105F87	Dehydratase
A7K99_03335	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A7K99_03340	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A7K99_03345	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
A7K99_03355	ENOG4105CV8	reductase
A7K99_03360	ENOG4105CF7	AraC family transcriptional regulator
A7K99_03365	ENOG4108K81	inner membrane protein YghB
A7K99_03370	ENOG4105C28	cystathionine
A7K99_03375	ENOG4105CWK	Biopolymer transport protein, ExbB
A7K99_03380	ENOG4108ZZF	transport protein (ExbD)
A7K99_03385	ENOG4105CSH	Transporter
A7K99_03390	ENOG4105BZU	Histidine kinase
A7K99_03395	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A7K99_03400	ENOG4105GSJ	Inner membrane protein ylaC
A7K99_03435	ENOG41090A1	ferritin
A7K99_03440	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A7K99_03445	ENOG4105DJB	Major Facilitator Superfamily
A7K99_03455	ENOG4105K3G	Periplasmic Protein
A7K99_03460	ENOG4105EYA	deoxyribonuclease
A7K99_03465	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A7K99_03470	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A7K99_03475	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
A7K99_03520	ENOG4107XZC	Restriction modification system DNA (Specificity
A7K99_03550	ENOG4105EAB	amino acid AbC transporter
A7K99_03555	ENOG4105C26	Dehydrogenase
A7K99_03565	ENOG4105ETS	cytosine purines uracil thiamine allantoin
A7K99_03570	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A7K99_03580	ENOG4105DBE	peroxidase
A7K99_03585	ENOG410650H	(LipO)protein
A7K99_03590	ENOG4105EKT	)-iron permease
A7K99_03600	ENOG4105E5K	Alpha-amylase
A7K99_03610	ENOG4105DZG	Dehydrogenase
A7K99_03625	ENOG4105CTU	Proline racemase
A7K99_03635	ENOG4105E5Q	amino acid AbC transporter
A7K99_03640	ENOG4105E5Q	amino acid AbC transporter
A7K99_03660	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A7K99_03680	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_03685	ENOG4105KT5	UmuD protein
A7K99_03690	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A7K99_03705	ENOG4108WAV	Transcriptional regulator
A7K99_03715	ENOG4105EE1	crotonyl-CoA reductase
A7K99_03720	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_03730	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A7K99_03745	ENOG4106UW1	Major Facilitator superfamily
A7K99_03760	ENOG4105K2J	Transcriptional regulator
A7K99_03770	ENOG4105CHR	reductase
A7K99_03780	ENOG4105K2J	Transcriptional regulator
A7K99_03785	ENOG41076YT	nitrate reductase, gamma subunit
A7K99_03790	ENOG4108NZN	Respiratory nitrate reductase 2 delta chain
A7K99_03795	ENOG4108IUE	nitrate reductase beta subunit
A7K99_03800	ENOG4105CRU	nitrate reductase, alpha subunit
A7K99_03805	ENOG4107QND	Nitrite extrusion protein
A7K99_03810	ENOG4105WZK	nitrite reductase NADPH small subunit
A7K99_03815	ENOG4107QZF	nitrite reductase NADPH large subunit
A7K99_03830	ENOG4105ECR	NmrA family
A7K99_03835	ENOG4105KVH	Transcriptional regulator
A7K99_03840	ENOG4105Q26	Siderophore-interacting protein
A7K99_03845	ENOG4105NTW	Transcriptional regulator
A7K99_03855	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A7K99_03860	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A7K99_03870	ENOG4105CXN	decarboxylase
A7K99_03875	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
A7K99_03880	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
A7K99_03885	ENOG4105CEN	a g-specific adenine glycosylase
A7K99_03895	ENOG41090ED	Protein with unknown function (DUF469)
A7K99_03900	ENOG4105K33	Periplasmic Protein
A7K99_03905	ENOG4105CSA	Coproporphyrinogen iii oxidase
A7K99_03910	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A7K99_03915	ENOG4108VIA	integral membrane protein
A7K99_03920	ENOG4105DFA	alanine racemase domain protein
A7K99_03925	ENOG4105CZX	twitching motility protein
A7K99_03940	ENOG4108UJU	UPF0301 protein
A7K99_03945	ENOG4105D7Z	glutathione synthase
A7K99_03950	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A7K99_03960	ENOG4107QNK	)-transporter
A7K99_03965	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A7K99_03975	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
A7K99_03980	ENOG4105CYW	agmatinase
A7K99_03985	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
A7K99_04000	ENOG4105CPQ	Dehydrogenase
A7K99_04005	ENOG4105E39	Enoyl-CoA hydratase
A7K99_04015	ENOG4107T8P	acyl-Coa dehydrogenase
A7K99_04020	ENOG4105CH2	amidohydrolase
A7K99_04025	ENOG4105J5J	Outer membrane porin
A7K99_04030	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A7K99_04040	ENOG4105BZA	Phosphoglycerate kinase
A7K99_04045	ENOG4105D2N	Aldolase
A7K99_04055	ENOG4106KE4	Dehydrogenase
A7K99_04060	ENOG4105D64	Mechanosensitive ion channel
A7K99_04065	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A7K99_04070	ENOG4105MPN	Membrane
A7K99_04080	ENOG4105E66	phosphoriboisomerase A
A7K99_04085	ENOG4108JQ1	Dehydrogenase
A7K99_04090	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A7K99_04105	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
A7K99_04115	ENOG4107RAQ	aminopeptidase
A7K99_04120	ENOG4105D0A	hydroxylase
A7K99_04125	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A7K99_04130	ENOG4108RWI	nicotinamidase
A7K99_04140	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
A7K99_04150	ENOG4105DU0	nucleoside hydrolase
A7K99_04155	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A7K99_04160	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A7K99_04165	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7K99_04175	ENOG4108UT2	hemolysin iii
A7K99_04180	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A7K99_04185	ENOG4105Y75	tpr repeat protein
A7K99_04195	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
A7K99_04200	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A7K99_04205	ENOG4105T95	Thiol disulfide interChange protein
A7K99_04210	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A7K99_04215	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A7K99_04220	ENOG4105CRK	lysyL-tRNA synthetase
A7K99_04230	ENOG4108MRJ	
A7K99_04235	ENOG4105DAY	polysaccharide export protein
A7K99_04250	ENOG4105D3Q	Sugar transferase
A7K99_04255	ENOG4108KBE	Glycosyl transferase, family 2
A7K99_04260	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A7K99_04270	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A7K99_04275	ENOG4105H63	Glycosyl transferase, family 2
A7K99_04330	ENOG4105EIP	mannose-6-phosphate isomerase
A7K99_04335	ENOG4108EQA	pts system
A7K99_04340	ENOG4105ETZ	PTS System
A7K99_04345	ENOG4105F3R	pts system mannose fructose sorbose family iid
A7K99_04350	ENOG4108NK4	UPF0266 membrane protein
A7K99_04360	ENOG4105F8D	glycoside hydrolase family 4
A7K99_04365	ENOG4105VCP	PTS System
A7K99_04370	ENOG4105CK1	PTS System
A7K99_04375	ENOG4105VZJ	PTS System
A7K99_04380	ENOG4105F27	Major Facilitator
A7K99_04385	ENOG4105RQF	LysR family Transcriptional regulator
A7K99_04395	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
A7K99_04400	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A7K99_04410	ENOG4105CJN	penicillin-binding protein
A7K99_04420	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A7K99_04425	ENOG4105BZS	acriflavin resistance protein
A7K99_04430	ENOG4105BZS	acriflavin resistance protein
A7K99_04440	ENOG4105CEY	Amp-dependent synthetase and ligase
A7K99_04445	ENOG4107S74	Lysophospholipid transporter LplT
A7K99_04450	ENOG4105CPC	Aldo Keto reductase
A7K99_04455	ENOG4105SUV	lipoprotein YgdR
A7K99_04460	ENOG4105EE5	Membrane protein terC
A7K99_04470	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A7K99_04475	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A7K99_04480	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A7K99_04485	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A7K99_04510	ENOG4105DSY	exodeoxyribonuclease V, gamma
A7K99_04515	ENOG4107QKA	exodeoxyribonuclease V beta
A7K99_04520	ENOG4107QYX	exodeoxyribonuclease v alpha
A7K99_04525	ENOG4107QZM	n-acetylglutamate synthase
A7K99_04535	ENOG4105D5Q	Arginine ornithine antiporter
A7K99_04540	ENOG4105CXN	decarboxylase
A7K99_04545	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A7K99_04575	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A7K99_04580	ENOG4105CUZ	uba thif-type nad fad binding protein
A7K99_04585	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A7K99_04590	ENOG4105C9B	Cysteine desulfurase
A7K99_04595	ENOG4105M5B	(LipO)protein
A7K99_04600	ENOG4105ETT	transcriptional Regulator, LysR family
A7K99_04605	ENOG4105M08	Membrane
A7K99_04610	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
A7K99_04615	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
A7K99_04620	ENOG4105EWT	decarboxylase family
A7K99_04630	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
A7K99_04635	ENOG4105WP7	tRNA pseudouridine synthase C
A7K99_04640	ENOG4105DR9	pseudouridine synthase
A7K99_04645	ENOG4105QDK	Flavodoxin
A7K99_04650	ENOG4105BZU	Histidine kinase
A7K99_04655	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A7K99_04660	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A7K99_04665	ENOG4105DXN	mazG family
A7K99_04675	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A7K99_04680	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A7K99_04760	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A7K99_04765	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A7K99_04770	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A7K99_04775	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A7K99_04780	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A7K99_04785	ENOG4108MXK	alkaline phosphatase isozyme conversion
A7K99_04790	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A7K99_04795	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A7K99_04805	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
A7K99_04810	ENOG4105N0Z	inner membrane protein ygbE
A7K99_04815	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A7K99_04825	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A7K99_04830	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A7K99_04835	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A7K99_04845	ENOG4108K5P	(LipO)protein
A7K99_04850	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A7K99_04855	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A7K99_04865	ENOG4105CVE	Lytic murein transglycosylase
A7K99_04870	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A7K99_04875	ENOG4107TH8	cina domain protein
A7K99_04880	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A7K99_04890	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A7K99_04895	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A7K99_04935	ENOG4107VXZ	Hydrolase
A7K99_04940	ENOG4105D9M	gamma-glutamylcysteine synthetase
A7K99_04945	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A7K99_04950	ENOG4108JU6	CBS domain protein
A7K99_04955	ENOG4106KVJ	cytochrome C assembly protein
A7K99_04960	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7K99_04965	ENOG4105K5M	30s ribosomal protein S16
A7K99_04970	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A7K99_04975	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A7K99_04980	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A7K99_04985	ENOG4105CUB	amino acid
A7K99_05000	ENOG4105DQ4	alcohol dehydrogenase
A7K99_05005	ENOG41073TP	transcriptional regulator
A7K99_05010	ENOG4105DMF	Dehydrogenase
A7K99_05015	ENOG4108Z9K	Osmotically inducible protein
A7K99_05050	ENOG4105RZQ	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity)
A7K99_05055	ENOG4105VIF	phosphate starvation-inducible protein
A7K99_05065	ENOG4105II7	pyrroline-5-carboxylate reductase
A7K99_05070	ENOG4108UPT	UPF0178 protein
A7K99_05075	ENOG4105G4C	Periplasmic ligand-binding sensor protein
A7K99_05080	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A7K99_05085	ENOG4105DRP	amino acid AbC transporter
A7K99_05090	ENOG4105EZ7	amino acid ABC transporter
A7K99_05100	ENOG4105CT1	(ABC) transporter
A7K99_05110	ENOG4105DH7	May be involved in recombination (By similarity)
A7K99_05115	ENOG4105CUB	amino acid
A7K99_05130	ENOG4105EYH	Exonuclease
A7K99_05135	ENOG4107RH8	nuclease SbcCD subunit D
A7K99_05140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A7K99_05145	ENOG4105BZU	Histidine kinase
A7K99_05155	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A7K99_05160	ENOG4105C85	amino acid
A7K99_05165	ENOG4105CUY	Mechanosensitive ion channel
A7K99_05175	ENOG4105D3R	alkyl hydroperoxide reductase
A7K99_05180	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
A7K99_05185	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A7K99_05195	ENOG4105VIE	preprotein translocase, subunit YajC
A7K99_05205	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A7K99_05210	ENOG4105VNT	transposase (IS4 family) protein
A7K99_05220	ENOG4109066	lysm domain bon superfamily protein
A7K99_05225	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A7K99_05230	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A7K99_05235	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A7K99_05240	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A7K99_05245	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A7K99_05250	ENOG4108ZAI	phosphatidylglycerophosphatase a
A7K99_05255	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A7K99_05260	ENOG4105CTB	Polyprenyl synthetase
A7K99_05265	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A7K99_05270	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A7K99_05275	ENOG4107S0N	DJ-1 family
A7K99_05280	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A7K99_05285	ENOG4108VPT	UPF0234 protein
A7K99_05290	ENOG4107RDB	Major Facilitator
A7K99_05295	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A7K99_05300	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
A7K99_05305	ENOG4105CCU	oxidase (Subunit III)
A7K99_05310	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A7K99_05315	ENOG4105E2S	oxidase) subunit II
A7K99_05320	ENOG4105EYM	Major Facilitator superfamily
A7K99_05325	ENOG4105IEY	(LipO)protein
A7K99_05330	ENOG4105M85	Bola protein
A7K99_05335	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A7K99_05340	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A7K99_05345	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A7K99_05350	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A7K99_05355	ENOG4105K70	DNA-binding protein
A7K99_05360	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A7K99_05365	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
A7K99_05370	ENOG4108TGP	Thioesterase superfamily protein
A7K99_05375	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A7K99_05385	ENOG4108XM1	transcriptional regulator AsnC family
A7K99_05390	ENOG4105BZ1	(ABC) transporter
A7K99_05395	ENOG4105BZ1	(ABC) transporter
A7K99_05400	ENOG4108YZA	Nitrogen regulatory protein pii
A7K99_05405	ENOG4105BZU	Histidine kinase
A7K99_05425	ENOG4105C29	acyl-CoA thioesterase
A7K99_05430	ENOG4108MNP	Glycoprotein polysaccharide metabolism
A7K99_05435	ENOG41080UX	Methyltransferase
A7K99_05445	ENOG4105KF5	hemolysin expression-modulating protein
A7K99_05450	ENOG4108UKR	Biofilm formation regulator YbaJ
A7K99_05455	ENOG4105YK5	50S ribosomal protein L36
A7K99_05465	ENOG4105BZS	acriflavin resistance protein
A7K99_05470	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A7K99_05475	ENOG4108IG5	Transcriptional regulator
A7K99_05480	ENOG4106428	Protein of unknown function (DUF2496)
A7K99_05490	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A7K99_05495	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A7K99_05500	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A7K99_05505	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A7K99_05510	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A7K99_05515	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A7K99_05520	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A7K99_05525	ENOG4107RE1	Inosine-guanosine kinase
A7K99_05530	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A7K99_05540	ENOG4105DUM	transcriptional regulator, lysR family
A7K99_05545	ENOG4108Z66	YbaK ebsC protein
A7K99_05550	ENOG4105MBR	gumn family
A7K99_05555	ENOG4105C59	p-type ATPase
A7K99_05560	ENOG4108Z6Z	Transcriptional regulator
A7K99_05565	ENOG4107QR8	Thioredoxin
A7K99_05570	ENOG4105E1F	short-chain dehydrogenase reductase
A7K99_05575	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A7K99_05580	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A7K99_05590	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A7K99_05595	ENOG4105C8N	cysteinyl-tRNA synthetase
A7K99_05600	ENOG4105WQ3	Rna-binding protein
A7K99_05605	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A7K99_05615	ENOG4105BZU	Histidine kinase
A7K99_05620	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_05645	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A7K99_05650	ENOG4105DDI	hemolysin-type calcium-binding region
A7K99_05670	ENOG4108JJ6	Type I secretion system ATPase
A7K99_05675	ENOG4107QZV	Type I secretion membrane fusion protein
A7K99_05680	ENOG4105DFG	type I secretion outer membrane protein
A7K99_05700	ENOG4107NQ8	LysR family Transcriptional regulator
A7K99_05705	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
A7K99_05710	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A7K99_05715	ENOG4105C08	Histidine kinase
A7K99_05730	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A7K99_05755	ENOG41075H3	AraC family transcriptional regulator
A7K99_05765	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A7K99_05770	ENOG4108YYC	ycei family
A7K99_05775	ENOG4108UW5	maltose o-acetyltransferase
A7K99_05780	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A7K99_05810	ENOG4105DQ4	alcohol dehydrogenase
A7K99_05815	ENOG4105KVH	Transcriptional regulator
A7K99_05825	ENOG4105E89	ABC transporter
A7K99_05830	ENOG4105EBR	Carboxylesterase
A7K99_05835	ENOG4105CPC	Aldo Keto reductase
A7K99_05845	ENOG4105E2X	shikimate dehydrogenase
A7K99_05860	ENOG4105EV8	ectoine hydroxylase
A7K99_05870	ENOG4106NDP	Transcriptional regulator
A7K99_05875	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
A7K99_05880	ENOG4108HKT	sucrose-6-phosphate hydrolase
A7K99_05890	ENOG4105D7K	pfkb domain protein
A7K99_05900	ENOG4105DG4	malate L-lactate dehydrogenase
A7K99_05910	ENOG4105VEQ	Cold shock protein
A7K99_05915	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
A7K99_05920	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A7K99_05925	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A7K99_05935	ENOG4105DZ1	carboxypeptidase
A7K99_05940	ENOG4105K6T	rare lipoprotein A
A7K99_05945	ENOG4105CNI	cell division protein FtsW
A7K99_05950	ENOG4105CJN	penicillin-binding protein
A7K99_05955	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A7K99_05960	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A7K99_05970	ENOG4105DJF	DNA polymerase III, delta' subunit
A7K99_05975	ENOG4108U2H	Rare lipoprotein B
A7K99_05980	ENOG4105C8T	Leucyl-tRNA synthetase
A7K99_05985	ENOG4105CDA	abc transporter atp-binding protein
A7K99_05990	ENOG4105DRP	amino acid AbC transporter
A7K99_05995	ENOG4105EAD	ABC transporter
A7K99_06000	ENOG4107RP9	extracellular solute-binding protein, family 3
A7K99_06005	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A7K99_06010	ENOG4108JU5	Magnesium and cobalt efflux protein
A7K99_06015	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A7K99_06020	ENOG4105C9A	Phoh family
A7K99_06030	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A7K99_06035	ENOG4105VNT	transposase (IS4 family) protein
A7K99_06075	ENOG4105CAQ	asparagine synthetase
A7K99_06085	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A7K99_06090	ENOG4105E2R	ROK family
A7K99_06095	ENOG4105CE4	GlcNAc 6-P deacetylase
A7K99_06100	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A7K99_06105	ENOG4105CI1	PTS System
A7K99_06130	ENOG41090R7	Ferric uptake
A7K99_06135	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A7K99_06140	ENOG4105NNH	LexA regulated protein
A7K99_06145	ENOG4105EV9	Alpha Beta Hydrolase
A7K99_06155	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
A7K99_06160	ENOG4107SEY	Conserved Protein
A7K99_06165	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A7K99_06170	ENOG4107QNR	UPF0135 protein
A7K99_06175	ENOG4105P4J	Allophanate hydrolase, subunit 1
A7K99_06180	ENOG4107R7A	Allophanate hydrolase subunit 2
A7K99_06190	ENOG4105E2X	shikimate dehydrogenase
A7K99_06195	ENOG4105BZN	citrate synthase
A7K99_06200	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
A7K99_06205	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
A7K99_06210	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A7K99_06215	ENOG4105E33	succinate dehydrogenase
A7K99_06220	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A7K99_06225	ENOG4105C7S	Dehydrogenase
A7K99_06230	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A7K99_06235	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A7K99_06240	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A7K99_06245	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A7K99_06250	ENOG4105KJB	cyd operon protein YbgE
A7K99_06255	ENOG4107YD3	Thioesterase
A7K99_06260	ENOG4105E02	MotA TolQ exbB proton channel
A7K99_06265	ENOG4105M8F	Biopolymer transport protein exbD tolR
A7K99_06270	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
A7K99_06270	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
A7K99_06280	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A7K99_06285	ENOG4105UFD	tol-pal system protein YbgF
A7K99_06320	ENOG4105CMR	udp-glucose 4-epimerase
A7K99_06335	ENOG4105PGM	cation diffusion facilitator family transporter
A7K99_06340	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A7K99_06345	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A7K99_06350	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A7K99_06360	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A7K99_06365	ENOG4105DKW	ABC transporter
A7K99_06370	ENOG4105F4R	Transcriptional regulator mode
A7K99_06375	ENOG4108K4B	hydrolase
A7K99_06380	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A7K99_06385	ENOG4108V1U	phospholipid-binding protein
A7K99_06390	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A7K99_06395	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A7K99_06400	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A7K99_06405	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A7K99_06410	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A7K99_06415	ENOG4108IV0	ABC, transporter
A7K99_06420	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A7K99_06425	ENOG4105CHW	UPF0052 protein
A7K99_06430	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A7K99_06435	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A7K99_06440	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A7K99_06445	ENOG4105M00	molybdopterin converting factor, subunit 1
A7K99_06450	ENOG4108ZAF	Molybdopterin
A7K99_06455	ENOG4107QS8	(LipO)protein
A7K99_06460	ENOG4105HFZ	Membrane
A7K99_06470	ENOG4105I9U	inner membrane protein ybhQ
A7K99_06475	ENOG4105C1J	atp-dependent rna helicase
A7K99_06480	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A7K99_06485	ENOG4105F9N	Major Facilitator Superfamily
A7K99_06490	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A7K99_06495	ENOG4105KHU	inner membrane protein YohD
A7K99_06500	ENOG41061WM	D-Alanyl-D-Alanine
A7K99_06505	ENOG4105EGS	Mechanosensitive ion channel
A7K99_06510	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A7K99_06520	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A7K99_06525	ENOG4105DVT	helicase
A7K99_06530	ENOG4108MTB	glycosyl transferase family
A7K99_06535	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
A7K99_06540	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
A7K99_06545	ENOG4108T1M	outer membrane protein x
A7K99_06550	ENOG4105VNT	transposase (IS4 family) protein
A7K99_06575	ENOG4105KST	dependent repressor
A7K99_06585	ENOG4105C5H	ABC transporter
A7K99_06590	ENOG4105D06	uba thif-type nad fad binding protein
A7K99_06595	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A7K99_06600	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A7K99_06605	ENOG4105DZ1	carboxypeptidase
A7K99_06610	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
A7K99_06615	ENOG4105D0C	transport protein
A7K99_06620	ENOG41090BQ	Glutaredoxin
A7K99_06630	ENOG4108DBC	nitroreductase
A7K99_06635	ENOG4108RMJ	sensory transduction regulator
A7K99_06640	ENOG4107RUE	extracellular solute-binding protein family 1
A7K99_06645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_06650	ENOG4105F38	ABC transporter, permease
A7K99_06655	ENOG4105D38	putrescine abc transporter
A7K99_06660	ENOG4105RBQ	inner membrane protein ybjO
A7K99_06665	ENOG4105DMR	ABC, transporter
A7K99_06670	ENOG4105GBT	ABC transporter
A7K99_06675	ENOG4106PMH	Extracellular solute-binding protein family 3
A7K99_06680	ENOG4105E5Z	arginine transporter ATP-binding subunit
A7K99_06685	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A7K99_06690	ENOG4105C5W	Aldolase
A7K99_06695	ENOG4105C7K	acetolactate synthase
A7K99_06700	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
A7K99_06705	ENOG4105VEQ	Cold shock protein
A7K99_06710	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A7K99_06715	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A7K99_06720	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A7K99_06725	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A7K99_06730	ENOG4108JJ8	(ABC) transporter
A7K99_06735	ENOG4108JJ9	ABC, transporter
A7K99_06740	ENOG4105C3M	thioredoxin reductase
A7K99_06745	ENOG4105EW9	transcriptional regulator AsnC family
A7K99_06750	ENOG4105CNU	cell division protein FtsK
A7K99_06760	ENOG4105D1H	recombination factor protein RarA
A7K99_06790	ENOG4108ISG	Major Facilitator
A7K99_06795	ENOG4105F1A	Pyruvate formate-lyase
A7K99_06800	ENOG4105C6N	Formate acetyltransferase
A7K99_06805	ENOG4105TMB	Formate nitrite transporter
A7K99_06810	ENOG4105DDY	UPF0142 protein ycaO
A7K99_06815	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A7K99_06820	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A7K99_06825	ENOG4105CAT	Cytidine monophosphate kinase
A7K99_06830	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A7K99_06840	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A7K99_06850	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A7K99_06855	ENOG4105W49	UPF0434 protein
A7K99_06865	ENOG4107VR7	transferase activity, transferring phosphorus-containing groups
A7K99_06870	ENOG4107S90	membrAne
A7K99_06875	ENOG4106371	Methyltransferase
A7K99_06880	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
A7K99_06885	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
A7K99_06895	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A7K99_06900	ENOG4105EAQ	(twin-arginine translocation) pathway signal
A7K99_06905	ENOG4105C5X	domain protein
A7K99_06910	ENOG4105CGF	Aromatic amino acid aminotransferase
A7K99_06920	ENOG4105C5S	asparaginyl-tRNA synthetase
A7K99_06930	ENOG4105CD8	aminopeptidase N
A7K99_06935	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A7K99_06940	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
A7K99_06945	ENOG4105QVC	MOSC domain-containing protein
A7K99_06950	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A7K99_06955	ENOG4105C5H	ABC transporter
A7K99_06960	ENOG4105F1S	paraquat-inducible protein a
A7K99_06965	ENOG4105DY2	Paraquat-inducible protein b
A7K99_06970	ENOG4108Q2G	(LipO)protein
A7K99_06980	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A7K99_06985	ENOG4105DAN	ATP-dependent protease
A7K99_06990	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
A7K99_07005	ENOG4108RZ1	DNA transformation protein
A7K99_07010	ENOG4105EM2	membrane
A7K99_07015	ENOG410901E	Membrane
A7K99_07020	ENOG41088T4	Helicase IV
A7K99_07025	ENOG4108Z5K	methylglyoxal synthase
A7K99_07030	ENOG4108Q67	UPF0319 protein
A7K99_07035	ENOG4105K4P	CoA-binding domain protein
A7K99_07040	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
A7K99_07045	ENOG4105DR4	Methyltransferase
A7K99_07050	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A7K99_07060	ENOG4108MN8	Membrane
A7K99_07075	ENOG4105D6F	Phosphatase
A7K99_07085	ENOG4105XVG	cytoplasmic protein
A7K99_07090	ENOG4105WH1	Two component transcriptional regulator luxr family
A7K99_07100	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A7K99_07110	ENOG4105ETT	transcriptional Regulator, LysR family
A7K99_07115	ENOG4108NIW	Leucine export protein LeuE
A7K99_07135	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
A7K99_07165	ENOG4108WUH	Transcriptional regulator, TetR family
A7K99_07175	ENOG4105N2W	Transcriptional regulator
A7K99_07180	ENOG4107VIJ	nudix hydrolase
A7K99_07190	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A7K99_07195	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A7K99_07200	ENOG4107RNH	Outer membrane receptor FepA
A7K99_07220	ENOG4105DSW	Fusaric acid resistance protein
A7K99_07230	ENOG4105D01	(LipO)protein
A7K99_07235	ENOG4105N5Z	UPF0267 protein
A7K99_07245	ENOG4105J12	Multidrug resistance protein mdtN
A7K99_07260	ENOG4105C0A	alcohol dehydrogenase
A7K99_07265	ENOG4105CV8	reductase
A7K99_07280	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
A7K99_07285	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
A7K99_07295	ENOG410633P	Hydantoin racemase
A7K99_07305	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A7K99_07315	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A7K99_07320	ENOG4105F27	Major Facilitator
A7K99_07350	ENOG4108ETV	ABC transporter
A7K99_07365	ENOG4105CHH	sulfate transporter
A7K99_07370	ENOG4105EIK	Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity)
A7K99_07380	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
A7K99_07385	ENOG4105NAC	(LipO)protein
A7K99_07390	ENOG4108W47	Acidic protein msyB
A7K99_07395	ENOG4105D1S	lipid A biosynthesis
A7K99_07400	ENOG4105C72	UPF0176 protein
A7K99_07415	ENOG4105PVA	Biofilm formation regulatory protein BssS
A7K99_07425	ENOG4105EKE	dihydroorotase
A7K99_07430	ENOG4105F3T	(LipO)protein
A7K99_07435	ENOG4105D9U	N-acetyltransferase
A7K99_07440	ENOG4105CJR	Integral membrane protein (MviN
A7K99_07455	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
A7K99_07465	ENOG4108ZC9	flagellar basal-body rod protein flgc
A7K99_07470	ENOG4105W00	Flagellar hook capping protein
A7K99_07475	ENOG4105BZE	flagellar hook protein, FlgE
A7K99_07480	ENOG4108KPB	Flagellar basal-body rod protein FlgF
A7K99_07485	ENOG4105CGA	flagellar basal-body rod protein FlgG
A7K99_07495	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A7K99_07500	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A7K99_07505	ENOG4105E1Q	flagellar hook-associated protein
A7K99_07510	ENOG4105DTJ	flagellar hook-associated protein
A7K99_07515	ENOG4107QQB	Ribonuclease E
A7K99_07520	ENOG4105EI2	Pseudouridine synthase
A7K99_07525	ENOG4107T9C	Alpha amylase catalytic region
A7K99_07535	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A7K99_07540	ENOG4105VGS	50s ribosomal protein l32
A7K99_07550	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A7K99_07555	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A7K99_07560	ENOG4105CHR	reductase
A7K99_07565	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A7K99_07570	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A7K99_07575	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
A7K99_07585	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A7K99_07590	ENOG4107QRG	dna polymerase iii
A7K99_07595	ENOG4105F8V	Hydrolase, tatD family
A7K99_07600	ENOG4105K59	histidine triad (HIT) protein
A7K99_07605	ENOG41090DQ	Lipoprotein
A7K99_07610	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
A7K99_07615	ENOG4108RUM	thiamine kinase
A7K99_07625	ENOG4105CEP	NADH dehydrogenase
A7K99_07630	ENOG4107MBR	17 kDa surface antigen
A7K99_07635	ENOG4108JA2	transcriptioN-repair coupling factor
A7K99_07640	ENOG4105D60	lipoprotein releasing system transmembrane protein
A7K99_07645	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A7K99_07650	ENOG4105D60	lipoprotein releasing system transmembrane protein
A7K99_07655	ENOG4105E2Y	ABC, transporter
A7K99_07660	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A7K99_07670	ENOG4105GVF	(ABC) transporter
A7K99_07675	ENOG4105FBW	Monooxygenase
A7K99_07680	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A7K99_07685	ENOG4108WF3	methyltransferase
A7K99_07690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_07700	ENOG4105EZE	Cupin 4 family protein
A7K99_07710	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A7K99_07715	ENOG4107QTF	adenylosuccinate lyase
A7K99_07720	ENOG41075W9	High frequency lysogenization protein HflD homolog
A7K99_07725	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A7K99_07735	ENOG4108R99	pseudouridine synthase
A7K99_07740	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A7K99_07765	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_07770	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_07780	ENOG4107RTG	Major Facilitator superfamily
A7K99_07790	ENOG4107653	Transcriptional regulator
A7K99_07810	ENOG4105CSH	Transporter
A7K99_07820	ENOG410642W	LysR family Transcriptional regulator
A7K99_07845	ENOG4105D3G	Pseudouridine synthase
A7K99_07850	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
A7K99_07860	ENOG4105EWC	Purine nucleoside phosphorylase
A7K99_07880	ENOG4105M0C	cytoplasmic protein
A7K99_07890	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A7K99_07895	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
A7K99_07900	ENOG4105Y3U	Transglycosylase-associated protein
A7K99_07910	ENOG4107SSZ	Phosphatase
A7K99_07915	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
A7K99_07930	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A7K99_07940	ENOG4108MHD	transport protein
A7K99_07945	ENOG4105D7K	pfkb domain protein
A7K99_07950	ENOG4105XFK	Ferrous iron transport protein A
A7K99_07960	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
A7K99_07970	ENOG4105F9E	Shikimate 5-dehydrogenase
A7K99_07975	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
A7K99_07980	ENOG4105C7K	acetolactate synthase
A7K99_07995	ENOG4106032	Glutathionylspermidine synthase
A7K99_08000	ENOG4105C7K	acetolactate synthase
A7K99_08005	ENOG4108N2Y	auxin Efflux
A7K99_08010	ENOG4105DVC	DnaJ domain protein
A7K99_08035	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_08040	ENOG4105W8I	Transcriptional regulator
A7K99_08045	ENOG4105C32	Amino acid ABC transporter (Permease)
A7K99_08050	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A7K99_08055	ENOG4105C0Z	ABC transporter
A7K99_08060	ENOG4108IV0	ABC, transporter
A7K99_08075	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A7K99_08090	ENOG41080IJ	Diacylglycerol kinase
A7K99_08100	ENOG4107RCI	amp-dependent synthetase and ligase
A7K99_08110	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A7K99_08115	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A7K99_08120	ENOG4108GH0	ATP-binding protein yghT
A7K99_08125	ENOG4108NDC	ATP-binding protein yghS
A7K99_08130	ENOG4106FPV	ATP-binding protein YghR
A7K99_08135	ENOG4108S55	polysaccharide biosynthesis protein
A7K99_08145	ENOG4108UUE	Transcriptional regulator
A7K99_08150	ENOG4108M8S	permease YjgP YjgQ family protein
A7K99_08165	ENOG4105CV8	reductase
A7K99_08190	ENOG4108V1U	phospholipid-binding protein
A7K99_08195	ENOG41069HH	4-oxalocrotonate tautomerase
A7K99_08200	ENOG4105EMU	Dehydrogenase
A7K99_08205	ENOG4107TJ9	Cytochrome
A7K99_08230	ENOG4105C57	major facilitator superfamily
A7K99_08240	ENOG4108XDN	Transcriptional regulator
A7K99_08245	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
A7K99_08250	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A7K99_08255	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A7K99_08270	ENOG4105SUU	thioesterase domain
A7K99_08280	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_08285	ENOG4105EMU	Dehydrogenase
A7K99_08290	ENOG4107SET	aldo keto reductase
A7K99_08320	ENOG4105C3G	gtp-binding protein
A7K99_08330	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
A7K99_08340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A7K99_08345	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A7K99_08350	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
A7K99_08355	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A7K99_08360	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A7K99_08365	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A7K99_08370	ENOG4108YY7	Invasion gene expression up-regulator SirB
A7K99_08375	ENOG41063JG	Transcriptional regulator
A7K99_08395	ENOG4105CJP	fad dependent oxidoreductase
A7K99_08405	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A7K99_08410	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
A7K99_08415	ENOG4105E5Q	amino acid AbC transporter
A7K99_08420	ENOG4105E5Q	amino acid AbC transporter
A7K99_08425	ENOG4105CDA	abc transporter atp-binding protein
A7K99_08430	ENOG4107V2S	Transcriptional regulator
A7K99_08435	ENOG4105CHR	reductase
A7K99_08445	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A7K99_08450	ENOG4105EWV	Sodium calcium exchanger membrane region
A7K99_08455	ENOG4108NH8	Cation transport protein
A7K99_08460	ENOG4105ID0	Putative invasin
A7K99_08470	ENOG4105F4X	arginine
A7K99_08475	ENOG4105C26	Dehydrogenase
A7K99_08480	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
A7K99_08485	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
A7K99_08490	ENOG4108SPG	Periplasmic Protein
A7K99_08495	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A7K99_08500	ENOG4105C2C	drug resistance transporter, Bcr CflA
A7K99_08505	ENOG4105KKI	DNA-binding transcriptional activator OsmE
A7K99_08515	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
A7K99_08520	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
A7K99_08525	ENOG4107PN8	YfeABCD locus regulator
A7K99_08530	ENOG4105FGM	Fructosamine kinase
A7K99_08535	ENOG4108NE3	Salt-induced outer membrane protein
A7K99_08545	ENOG4105DRR	Transcriptional regulator, GntR family
A7K99_08555	ENOG4105C22	threonyL-tRNA synthetase
A7K99_08565	ENOG41082NX	50s ribosomal protein l35
A7K99_08570	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A7K99_08585	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A7K99_08590	ENOG4108QBX	(LipO)protein
A7K99_08595	ENOG4105CNG	UPF0061 protein
A7K99_08605	ENOG4105IPI	Membrane
A7K99_08610	ENOG4105CQB	FAD linked oxidase domain protein
A7K99_08620	ENOG4105GVF	(ABC) transporter
A7K99_08625	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A7K99_08635	ENOG4105VNT	transposase (IS4 family) protein
A7K99_08640	ENOG4105CA9	Pyruvate kinase
A7K99_08645	ENOG4105CG3	alpha amylase, catalytic region
A7K99_08650	ENOG4105C5Y	PTS System
A7K99_08655	ENOG4105D4X	repressor
A7K99_08675	ENOG4107QI1	Mate efflux family protein
A7K99_08680	ENOG4108R6K	riboflavin synthase, subunit alpha
A7K99_08685	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A7K99_08690	ENOG4105CZQ	inner membrane transport protein YdhC
A7K99_08695	ENOG4105F52	Transcriptional regulator
A7K99_08700	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_08705	ENOG4105K4H	Nlp p60 protein
A7K99_08710	ENOG4105M2J	Glutaredoxin
A7K99_08715	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A7K99_08720	ENOG4108UYE	Lactoylglutathione lyase
A7K99_08725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_08730	ENOG4105DSW	Fusaric acid resistance protein
A7K99_08735	ENOG4105Y49	secretion protein, HlyD family
A7K99_08750	ENOG4108XTF	Outer Membrane Lipoprotein
A7K99_08755	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A7K99_08760	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A7K99_08770	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A7K99_08790	ENOG4105C2D	reductase
A7K99_08795	ENOG4105CBN	LysR family transcriptional regulator
A7K99_08805	ENOG4105CSM	endonuclease III
A7K99_08810	ENOG4105DZB	Electron transport complex
A7K99_08815	ENOG4108UQQ	Electron transport complex
A7K99_08820	ENOG4105D6A	Electron transport complex
A7K99_08830	ENOG4108R3D	Electron transport complex
A7K99_08835	ENOG4105DGN	Electron transport complex
A7K99_08840	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A7K99_08850	ENOG4106J39	exported protein
A7K99_08855	ENOG4105C9Q	fumarate hydratase class II
A7K99_08860	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
A7K99_08875	ENOG4105UEI	Transcriptional Regulator AraC Family
A7K99_08905	ENOG4105DKK	Benzoate
A7K99_08910	ENOG4108JCI	Transcriptional regulator
A7K99_08915	ENOG4105D3W	isochorismatase
A7K99_08920	ENOG4108KK1	membrane protein AbrB duplication
A7K99_08925	ENOG4105CHB	tonB-dependent Receptor
A7K99_08935	ENOG4108IGT	Dipeptidase
A7K99_08940	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
A7K99_08955	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A7K99_08960	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
A7K99_08965	ENOG4105CXG	d-lactate dehydrogenase
A7K99_08970	ENOG4108RCM	Nitroreductase
A7K99_08975	ENOG4107ZT3	family UPF0126
A7K99_08985	ENOG4108TGY	Glutathione S-transferase
A7K99_08995	ENOG4108IJ9	(ABC) transporter
A7K99_09005	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
A7K99_09025	ENOG4105ECM	Sensor protein basS pmrB
A7K99_09030	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A7K99_09035	ENOG4105DIJ	Phosphoethanolamine transferase
A7K99_09040	ENOG41090BB	DNA mismatch endonuclease (vsr)
A7K99_09045	ENOG4105CH6	catalase
A7K99_09055	ENOG4107XWI	flavin reductase domain protein, FMN-binding
A7K99_09060	ENOG4105CV8	reductase
A7K99_09065	ENOG4105DWT	malate dehydrogenase (quinone)
A7K99_09070	ENOG4105FFC	UPF0187 protein
A7K99_09075	ENOG4105C6X	Major Facilitator
A7K99_09080	ENOG4105TW1	Carbohydrate-selective porin OprB
A7K99_09085	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A7K99_09090	ENOG4105J76	Periplasmic binding protein
A7K99_09095	ENOG4105E0A	ABC, transporter
A7K99_09110	ENOG4105IBP	Cyclic peptide transporter
A7K99_09140	ENOG4105CH2	amidohydrolase
A7K99_09145	ENOG4105E89	ABC transporter
A7K99_09155	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A7K99_09165	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A7K99_09170	ENOG4108WUH	Transcriptional regulator, TetR family
A7K99_09185	ENOG4105HEI	LysR family (Transcriptional regulator
A7K99_09205	ENOG4105CHF	Glutathione S-transferase
A7K99_09210	ENOG4106KED	esterase YpfH
A7K99_09235	ENOG410907W	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport
A7K99_09255	ENOG4105C2W	permease
A7K99_09260	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A7K99_09270	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
A7K99_09280	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
A7K99_09285	ENOG4108R86	Transcriptional regulator
A7K99_09295	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
A7K99_09315	ENOG4107B2H	carbonic anhydrase
A7K99_09320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A7K99_09325	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A7K99_09350	ENOG41060NJ	transcriptional regulator
A7K99_09365	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A7K99_09370	ENOG4105ERH	Fumarylacetoacetate hydrolase
A7K99_09375	ENOG4108RNS	Exports L-alanine (By similarity)
A7K99_09380	ENOG4108M8W	Monooxygenase
A7K99_09390	ENOG4105DJB	Major Facilitator Superfamily
A7K99_09410	ENOG4105F9U	Dehydrogenase
A7K99_09415	ENOG4106P37	HTH-type transcriptional regulator YjhI
A7K99_09420	ENOG4105MP9	class II Aldolase
A7K99_09425	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A7K99_09430	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A7K99_09440	ENOG4105CSH	Transporter
A7K99_09450	ENOG4105DUM	transcriptional regulator, lysR family
A7K99_09460	ENOG4105MDS	4-oxalocrotonate tautomerase
A7K99_09465	ENOG4108048	decarboxylase
A7K99_09470	ENOG4107NQ8	LysR family Transcriptional regulator
A7K99_09490	ENOG4105VNT	transposase (IS4 family) protein
A7K99_09495	ENOG4107TJ9	Cytochrome
A7K99_09510	ENOG4105EMK	carboxylate amino acid amine transporter
A7K99_09520	ENOG4107F3J	Amp-dependent synthetase and ligase
A7K99_09555	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A7K99_09565	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
A7K99_09585	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A7K99_09595	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A7K99_09605	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A7K99_09615	ENOG4105CPQ	Dehydrogenase
A7K99_09620	ENOG4105CHR	reductase
A7K99_09630	ENOG4105CZE	histidine utilization repressor
A7K99_09635	ENOG4108JPW	Aminotransferase
A7K99_09640	ENOG4105DY8	decarboxylase
A7K99_09650	ENOG41067SE	Tetr family transcriptional regulator
A7K99_09660	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A7K99_09665	ENOG4105BZS	acriflavin resistance protein
A7K99_09670	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A7K99_09675	ENOG4105S10	periplasmic binding protein
A7K99_09695	ENOG4105ES4	Nitrilase
A7K99_09700	ENOG4108W5M	transcriptional regulator
A7K99_09705	ENOG4105PY6	Phenolic acid decarboxylase
A7K99_09710	ENOG4105VNT	transposase (IS4 family) protein
A7K99_09715	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A7K99_09735	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_09750	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A7K99_09755	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A7K99_09760	ENOG4105DUM	transcriptional regulator, lysR family
A7K99_09770	ENOG4105F38	ABC transporter, permease
A7K99_09775	ENOG4105D38	putrescine abc transporter
A7K99_09780	ENOG4105H3G	oxidoreductase
A7K99_09785	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
A7K99_09795	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A7K99_09800	ENOG4107R3N	Filamentation induced by cAMP protein fic
A7K99_09810	ENOG4105JQN	Transcriptional regulator
A7K99_09820	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
A7K99_09825	ENOG4105CPC	Aldo Keto reductase
A7K99_09835	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
A7K99_09840	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
A7K99_09845	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A7K99_09850	ENOG410642W	LysR family Transcriptional regulator
A7K99_09855	ENOG4107S5I	aldo keto reductase
A7K99_09870	ENOG4105KSC	Transcriptional regulator, TraR DksA family
A7K99_09875	ENOG4108VKG	metal-dependent hydrolase
A7K99_09885	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A7K99_09900	ENOG41067SE	Tetr family transcriptional regulator
A7K99_09905	ENOG41061H0	Monooxygenase
A7K99_09910	ENOG4107QUY	Guanine deaminase
A7K99_09915	ENOG4105EMU	Dehydrogenase
A7K99_09920	ENOG4105M5Q	UPF0482 protein
A7K99_09925	ENOG4105KBG	Protein of unknown function (DUF1161)
A7K99_09930	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A7K99_09935	ENOG4105DAG	ROK family
A7K99_09940	ENOG4106NZI	LysR family Transcriptional regulator
A7K99_09945	ENOG4105D94	Major Facilitator Superfamily
A7K99_09950	ENOG4105CPW	cytochrome b561
A7K99_09955	ENOG4105F27	Major Facilitator
A7K99_09960	ENOG4105KWI	UPF0339 protein
A7K99_09965	ENOG4105ETT	transcriptional Regulator, LysR family
A7K99_09970	ENOG4108DG9	Smr protein MutS2
A7K99_09975	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A7K99_09980	ENOG4105Q9Y	Universal stress protein
A7K99_09985	ENOG4105C5D	exported protein
A7K99_09990	ENOG4105D5Q	Arginine ornithine antiporter
A7K99_10000	ENOG4107EXC	regulatoR
A7K99_10005	ENOG4105JJR	Histidine kinase
A7K99_10010	ENOG4105CTD	carboxy-peptidase
A7K99_10020	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
A7K99_10025	ENOG4105CQ7	ATP-dependent helicase
A7K99_10030	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A7K99_10035	ENOG410689M	(LipO)protein
A7K99_10040	ENOG4107H52	Dicarboxylate transport
A7K99_10045	ENOG4105C5I	Dehydrogenase
A7K99_10055	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A7K99_10065	ENOG4107QSI	ABC, transporter
A7K99_10070	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A7K99_10080	ENOG4106K28	UPF0283 membrane protein
A7K99_10085	ENOG4105CM6	amino acid regulated cytosolic protein
A7K99_10090	ENOG4105NNG	Peripheral inner membrane phage-shock protein
A7K99_10095	ENOG4105FM1	phage shock protein C
A7K99_10100	ENOG4105YYT	phage shock protein B
A7K99_10105	ENOG41087YS	Phage shock protein A
A7K99_10110	ENOG4105E51	psp operon transcriptional activator
A7K99_10115	ENOG4108HIY	periplasmic
A7K99_10120	ENOG4108I5W	peptide transport system, permease protein
A7K99_10125	ENOG4108EU3	peptide transport system, permease
A7K99_10130	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A7K99_10135	ENOG4108JQ2	peptide transport system atp-binding protein
A7K99_10140	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A7K99_10150	ENOG4105DUM	transcriptional regulator, lysR family
A7K99_10155	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
A7K99_10160	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
A7K99_10165	ENOG41061RM	osmotically inducible lipoprotein
A7K99_10170	ENOG4108ZJT	translation initiation factor, Sui1
A7K99_10180	ENOG4105CFV	Tetratricopeptide repeat protein
A7K99_10185	ENOG4105Q4A	inner membrane protein yciS
A7K99_10190	ENOG4105EYK	Phosphatidylglycerophosphatase B
A7K99_10195	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
A7K99_10200	ENOG4107QM5	aconitate hydratase
A7K99_10205	ENOG4107R11	Transcriptional regulator
A7K99_10210	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A7K99_10220	ENOG4105RKX	Protein of unknown function (DUF2498)
A7K99_10225	ENOG4105ERU	peptidase
A7K99_10230	ENOG4105UBK	short-chain dehydrogenase reductase
A7K99_10240	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A7K99_10245	ENOG4105DB7	PHP domain protein
A7K99_10250	ENOG4105CRQ	synthase (Component I)
A7K99_10255	ENOG4108EFP	Anthranilate synthase component II
A7K99_10260	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A7K99_10265	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A7K99_10275	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A7K99_10285	ENOG4105EIF	outer membrane protein W
A7K99_10290	ENOG4108S3I	UPF0259 membrane protein
A7K99_10295	ENOG4107835	probably involved in intracellular septation (By similarity)
A7K99_10300	ENOG4105NAU	thioesterase Superfamily protein
A7K99_10305	ENOG410822N	TonB family
A7K99_10310	ENOG4105K9H	YciI-like protein
A7K99_10325	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A7K99_10330	ENOG4108W5H	UPF0263 protein
A7K99_10335	ENOG4108EKI	Dehydrogenase
A7K99_10350	ENOG4107104	thymidine kinase
A7K99_10365	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A7K99_10370	ENOG4105I93	response regulator
A7K99_10380	ENOG4105CIY	formyltetrahydrofolate deformylase
A7K99_10410	ENOG4105CGK	Exodeoxyribonuclease III
A7K99_10415	ENOG4105MTM	Protein of unknown function (DUF1496)
A7K99_10420	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A7K99_10425	ENOG41069NU	Nitroreductase
A7K99_10430	ENOG4105D07	Signal peptide peptidase, SppA
A7K99_10435	ENOG4105HDK	L-asparaginase
A7K99_10440	ENOG4105VUT	cytoplasmic protein
A7K99_10460	ENOG4105DSB	aldose 1-epimerase
A7K99_10465	ENOG4105GNX	MltA-interacting MipA family protein
A7K99_10475	ENOG4105CYN	Serine protein kinase
A7K99_10480	ENOG4106AKX	UPF0229 protein
A7K99_10490	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
A7K99_10500	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A7K99_10505	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A7K99_10510	ENOG4105ED1	spovr family
A7K99_10525	ENOG4108ZZ3	UPF0260 protein
A7K99_10530	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
A7K99_10535	ENOG4105VNG	YcgL domain-containing protein
A7K99_10540	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A7K99_10545	ENOG4107QMS	site-determining protein
A7K99_10550	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
A7K99_10555	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A7K99_10560	ENOG4105CEY	Amp-dependent synthetase and ligase
A7K99_10565	ENOG4105Y4Z	Outer Membrane Lipoprotein
A7K99_10570	ENOG41072GX	Peptidase M22 Glycoprotease
A7K99_10575	ENOG4105DVT	helicase
A7K99_10580	ENOG4105M4H	endoribonuclease L-psp
A7K99_10585	ENOG4105X5C	UPF0181 protein
A7K99_10590	ENOG4105CRQ	synthase (Component I)
A7K99_10595	ENOG4105P8F	nudix hydrolase
A7K99_10600	ENOG4105EJQ	L-serine dehydratase
A7K99_10605	ENOG4105EE5	Membrane protein terC
A7K99_10610	ENOG4105DHI	Methyltransferase
A7K99_10615	ENOG4105VEQ	Cold shock protein
A7K99_10625	ENOG4105Q3Y	exported protein
A7K99_10630	ENOG4105TIK	
A7K99_10635	ENOG4105D0M	Protease HtpX homolog
A7K99_10640	ENOG4105CN1	protease
A7K99_10645	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A7K99_10650	ENOG4108ZGC	gaf domain protein
A7K99_10655	ENOG4105H2K	paraquat-inducible protein a
A7K99_10660	ENOG4105DY2	Paraquat-inducible protein b
A7K99_10665	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A7K99_10670	ENOG4105NKT	exported protein
A7K99_10675	ENOG4108PNC	copper resistance
A7K99_10680	ENOG4105MPK	DNA polymerase III subunit theta
A7K99_10685	ENOG4105UMD	exodeoxyribonuclease X
A7K99_10690	ENOG4105CUG	Oligopeptidase b
A7K99_10695	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A7K99_10710	ENOG4108NUU	Transcriptional regulator
A7K99_10715	ENOG4108ESX	Receptor
A7K99_10725	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A7K99_10730	ENOG4105CA9	Pyruvate kinase
A7K99_10735	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A7K99_10740	ENOG4105DR5	peptidase
A7K99_10745	ENOG4105NXV	High-affinity zinc uptake system protein
A7K99_10750	ENOG4105FDK	ABC transporter
A7K99_10755	ENOG4105FAV	ABC, transporter
A7K99_10760	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A7K99_10765	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A7K99_10770	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A7K99_10775	ENOG4105CDY	transcriptional regulatory protein
A7K99_10780	ENOG4108TIT	dATP pyrophosphohydrolase
A7K99_10785	ENOG4105C9M	aspartyl-trna synthetase
A7K99_10790	ENOG41081XQ	Conserved Protein
A7K99_10795	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A7K99_10800	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A7K99_10805	ENOG4106N3A	copper homeostasis protein cutc
A7K99_10810	ENOG4106ZCM	YecM protein
A7K99_10815	ENOG4105C75	arginyL-tRNA synthetase
A7K99_10825	ENOG4105D7B	Flagellar biosynthesis protein flha
A7K99_10830	ENOG4105D00	flagellar biosynthetic protein flhB
A7K99_10835	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
A7K99_10840	ENOG4108VYJ	response regulator receiver protein
A7K99_10850	ENOG4105BZU	Histidine kinase
A7K99_10855	ENOG4105C8Q	Methyl-accepting chemotaxis
A7K99_10860	ENOG4108V3W	Chemotaxis protein, CheW
A7K99_10865	ENOG4105CBS	Chea signal transduction histidine kinase
A7K99_10870	ENOG4105ER2	Ompa motb domain protein
A7K99_10875	ENOG4107RD7	Flagellar Motor Protein, MotA
A7K99_10880	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
A7K99_10885	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
A7K99_10895	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
A7K99_10905	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A7K99_10925	ENOG4107S7U	Sulfide dehydrogenase
A7K99_10930	ENOG4105CHR	reductase
A7K99_10935	ENOG4105CEE	C4-dicarboxylate transporter
A7K99_10945	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
A7K99_10965	ENOG4105D5M	phosphate starvation-inducible protein
A7K99_10970	ENOG4105CK7	Sodium proline symporter
A7K99_10975	ENOG4105C26	Dehydrogenase
A7K99_10990	ENOG4105EJC	lysr family transcriptional regulator
A7K99_10995	ENOG4108M9K	flagella biosynthesis protein FliZ
A7K99_11000	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A7K99_11010	ENOG4107RGC	Glycosyl transferase, family 2
A7K99_11025	ENOG4105DTS	flagellar hook-associated
A7K99_11030	ENOG4105MQ3	flagellar protein FliS
A7K99_11040	ENOG4105JCU	Inherit from NOG: (Lipo)protein
A7K99_11050	ENOG4105SUT	Transcriptional Regulator AraC Family
A7K99_11055	ENOG4105GIJ	Glycine betaine
A7K99_11070	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A7K99_11075	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A7K99_11080	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A7K99_11085	ENOG41090PJ	Flagellar assembly protein
A7K99_11090	ENOG4108JIR	Flagellum-specific ATP synthase
A7K99_11100	ENOG4105WF4	Flagellar hook-length control protein
A7K99_11105	ENOG4107ZI8	flagellar basal body-associated protein flil
A7K99_11110	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A7K99_11115	ENOG4105DD5	Flagellar motor switch protein
A7K99_11120	ENOG4105K0P	flagellar biosynthesis protein
A7K99_11125	ENOG4105CN7	Flagellar biosynthetic protein FliP
A7K99_11130	ENOG4105VS8	Flagellar biosynthetic protein fliq
A7K99_11135	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A7K99_11145	ENOG4105VZF	DsrB protein
A7K99_11150	ENOG4105CKW	Inner membrane protein yedI
A7K99_11160	ENOG4105EST	Metal Dependent Phosphohydrolase
A7K99_11165	ENOG4105CSH	Transporter
A7K99_11175	ENOG4105FDK	ABC transporter
A7K99_11180	ENOG4105CC5	ABC transporter
A7K99_11190	ENOG4105FCK	Membrane
A7K99_11195	ENOG4105D2S	major facilitator superfamily
A7K99_11210	ENOG4107F9Y	LysR family transcriptional regulator
A7K99_11225	ENOG4105JSC	dimethylmenaquinone methyltransferase
A7K99_11270	ENOG41062ES	Transcriptional regulator
A7K99_11285	ENOG4107QN1	sodium solute
A7K99_11290	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A7K99_11295	ENOG4105EGI	Transcriptional regulator
A7K99_11300	ENOG4108ZHR	arsR family transcriptional regulator
A7K99_11315	ENOG4105F27	Major Facilitator
A7K99_11320	ENOG4105EJC	lysr family transcriptional regulator
A7K99_11340	ENOG4105C57	major facilitator superfamily
A7K99_11345	ENOG4105C6F	GntR Family Transcriptional Regulator
A7K99_11350	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A7K99_11370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_11375	ENOG4105D2M	Aldolase
A7K99_11390	ENOG4105E98	transcriptional regulator DeoR family
A7K99_11395	ENOG4107UEK	pfkb domain protein
A7K99_11410	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A7K99_11440	ENOG4106NZI	LysR family Transcriptional regulator
A7K99_11445	ENOG4105TW1	Carbohydrate-selective porin OprB
A7K99_11455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_11460	ENOG4105CPT	Alpha beta hydrolase
A7K99_11465	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A7K99_11505	ENOG4107RSM	transcriptional regulator
A7K99_11510	ENOG4105JSC	dimethylmenaquinone methyltransferase
A7K99_11515	ENOG4105D4T	Citrate transporter
A7K99_11520	ENOG4108IJ8	ABC transporter
A7K99_11525	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
A7K99_11530	ENOG4105E90	ABC transporter
A7K99_11540	ENOG4105CPU	Monooxygenase
A7K99_11565	ENOG4105DXI	Major Facilitator superfamily
A7K99_11580	ENOG4105CNM	Receptor
A7K99_11585	ENOG4105GVF	(ABC) transporter
A7K99_11590	ENOG4105C2C	drug resistance transporter, Bcr CflA
A7K99_11615	ENOG4105EW9	transcriptional regulator AsnC family
A7K99_11625	ENOG4108T2C	cysteine dioxygenase type I
A7K99_11635	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A7K99_11645	ENOG4105GVF	(ABC) transporter
A7K99_11650	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A7K99_11655	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
A7K99_11665	ENOG4108V1U	phospholipid-binding protein
A7K99_11730	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_11745	ENOG4105DQ4	alcohol dehydrogenase
A7K99_11760	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_11790	ENOG4105EU0	Major facilitator Superfamily
A7K99_11800	ENOG4105EMU	Dehydrogenase
A7K99_11805	ENOG4105C57	major facilitator superfamily
A7K99_11825	ENOG4105CC0	LysR family Transcriptional regulator
A7K99_11850	ENOG4105N1F	Hnh endonuclease
A7K99_11865	ENOG4108NNI	Beta-lactamase domain-containing protein
A7K99_11870	ENOG4105C0A	alcohol dehydrogenase
A7K99_11875	ENOG4105C26	Dehydrogenase
A7K99_11890	ENOG4105BZU	Histidine kinase
A7K99_11910	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
A7K99_11925	ENOG4106R3P	AraC family transcriptional regulator
A7K99_11935	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A7K99_11940	ENOG4105DM4	PTS System
A7K99_11945	ENOG4108YRF	PTS System
A7K99_11950	ENOG4108XCZ	PTS System
A7K99_11975	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
A7K99_11980	ENOG4105K78	MarR family Transcriptional regulator
A7K99_11990	ENOG4105E5Q	amino acid AbC transporter
A7K99_11995	ENOG4105CDA	abc transporter atp-binding protein
A7K99_12000	ENOG4105EAB	amino acid AbC transporter
A7K99_12010	ENOG4105EJC	lysr family transcriptional regulator
A7K99_12015	ENOG4105TMB	Formate nitrite transporter
A7K99_12020	ENOG4105CYM	Glutathione S-transferase
A7K99_12025	ENOG4105FDP	GntR family transcriptional regulator
A7K99_12030	ENOG4108TFM	Kinase, PfkB family
A7K99_12035	ENOG4108KD5	ADP-ribosylation crystallin J1
A7K99_12040	ENOG4105EAA	nucleoside
A7K99_12045	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A7K99_12050	ENOG4108XHQ	(2Fe-2S)-binding domain protein
A7K99_12055	ENOG4108VHT	MarR family transcriptional regulator
A7K99_12060	ENOG4105CSP	Major Facilitator Superfamily
A7K99_12065	ENOG4105C2W	permease
A7K99_12070	ENOG4108UAU	isochorismatase
A7K99_12075	ENOG4105RE0	Asp Glu hydantoin racemase
A7K99_12085	ENOG4105MSY	salicylate hydroxylase
A7K99_12095	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
A7K99_12100	ENOG4105CKI	cobalamin synthesis protein
A7K99_12105	ENOG4105BZU	Histidine kinase
A7K99_12110	ENOG4105UQX	Mate efflux family protein
A7K99_12115	ENOG4105FYV	Amp nucleosidase
A7K99_12120	ENOG4105C7N	Xanthine uracil vitamin C permease
A7K99_12140	ENOG4105EAD	ABC transporter
A7K99_12145	ENOG4105CDA	abc transporter atp-binding protein
A7K99_12170	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
A7K99_12175	ENOG4107RSM	transcriptional regulator
A7K99_12190	ENOG4105KME	endoribonuclease L-psp
A7K99_12205	ENOG4107UWC	ABC, transporter
A7K99_12210	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A7K99_12230	ENOG4105DCT	glycerol dehydrogenase
A7K99_12250	ENOG4106TNF	Periplasmic binding protein
A7K99_12260	ENOG4105E5Q	amino acid AbC transporter
A7K99_12265	ENOG4105CH7	arginosuccinase
A7K99_12270	ENOG4105EVZ	LysR family transcriptional regulator
A7K99_12275	ENOG4105DRR	Transcriptional regulator, GntR family
A7K99_12300	ENOG4105F27	Major Facilitator
A7K99_12305	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A7K99_12310	ENOG4105H3G	oxidoreductase
A7K99_12345	ENOG4107SQD	Transcriptional regulator, GntR family
A7K99_12350	ENOG4105C9B	Cysteine desulfurase
A7K99_12355	ENOG4105ESN	nucleotide-binding protein
A7K99_12375	ENOG4105C6T	cysteine synthase
A7K99_12380	ENOG4105D7W	serine acetyltransferase
A7K99_12385	ENOG4105D7T	ABC transporter
A7K99_12390	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A7K99_12395	ENOG4105SG9	biopolymer transport protein, ExbD
A7K99_12405	ENOG4105WQ5	TonB family
A7K99_12415	ENOG4107UWC	ABC, transporter
A7K99_12420	ENOG4107ZSV	Receptor
A7K99_12425	ENOG4105EKC	
A7K99_12455	ENOG4105CMG	Carbohydrate kinase
A7K99_12460	ENOG4108KAM	Transcriptional regulator
A7K99_12470	ENOG4105CNM	Receptor
A7K99_12475	ENOG4108NS2	receptor
A7K99_12480	ENOG4105C26	Dehydrogenase
A7K99_12505	ENOG4105CPC	Aldo Keto reductase
A7K99_12510	ENOG4105N0E	Protein of unknown function (DUF2543)
A7K99_12515	ENOG4108MJ3	acetyltransferase
A7K99_12520	ENOG4105CC0	LysR family Transcriptional regulator
A7K99_12525	ENOG4105C57	major facilitator superfamily
A7K99_12540	ENOG4108URH	decarboxylase
A7K99_12545	ENOG4105E0A	ABC, transporter
A7K99_12550	ENOG4105DQ5	transport system permease protein
A7K99_12560	ENOG4108MES	Periplasmic binding protein
A7K99_12585	ENOG4105EGI	Transcriptional regulator
A7K99_12595	ENOG4107258	Transcriptional regulator
A7K99_12615	ENOG4105C5I	Dehydrogenase
A7K99_12620	ENOG4105CT4	transporter
A7K99_12625	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
A7K99_12630	ENOG4105DJB	Major Facilitator Superfamily
A7K99_12645	ENOG4105J5J	Outer membrane porin
A7K99_12650	ENOG4105C4B	ABC transporter, permease
A7K99_12655	ENOG41083J0	(ABC) transporter
A7K99_12660	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A7K99_12665	ENOG41090HJ	UPF0265 protein
A7K99_12670	ENOG4105DR8	Membrane
A7K99_12675	ENOG4105DZ1	carboxypeptidase
A7K99_12685	ENOG4105YVS	arsR family transcriptional regulator
A7K99_12835	ENOG41061CV	Terminase small subunit 
A7K99_12855	ENOG4105KUS	lysozyme
A7K99_12865	ENOG4105HGD	Antitermination protein
A7K99_12970	ENOG4108UUM	single-stranded DNA-binding protein
A7K99_13025	ENOG4105DFP	Integrase
A7K99_13030	ENOG4105CJB	Exodeoxyribonuclease I
A7K99_13035	ENOG4105CUB	amino acid
A7K99_13040	ENOG4108535	NAD dependent epimerase/dehydratase family
A7K99_13045	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A7K99_13050	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A7K99_13055	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A7K99_13060	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A7K99_13065	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A7K99_13070	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A7K99_13075	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A7K99_13080	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A7K99_13090	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
A7K99_13100	ENOG4105C5Y	PTS System
A7K99_13105	ENOG4105CS2	ec 3.2.1.21
A7K99_13110	ENOG4105E89	ABC transporter
A7K99_13120	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A7K99_13135	ENOG4108TJN	glycosyl transferase group 1
A7K99_13145	ENOG4105EY8	ABC transporter
A7K99_13175	ENOG4105CMR	udp-glucose 4-epimerase
A7K99_13180	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A7K99_13185	ENOG4108GAE	asmA family
A7K99_13200	ENOG4105MH5	phosphoesterase PA-phosphatase related protein
A7K99_13205	ENOG4105R8A	Heat shock protein
A7K99_13215	ENOG4105BZS	acriflavin resistance protein
A7K99_13230	ENOG4105EB3	Histidine kinase
A7K99_13235	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A7K99_13240	ENOG4105CFP	Peptidase U32
A7K99_13245	ENOG4107TE5	Lipid kinase
A7K99_13250	ENOG4105DWF	phosphomethylpyrimidine kinase
A7K99_13260	ENOG4105E0K	tonB-dependent siderophore receptor
A7K99_13265	ENOG4105C1J	atp-dependent rna helicase
A7K99_13285	ENOG4108JU3	Alkyl hydroperoxide reductase
A7K99_13290	ENOG4105D3R	alkyl hydroperoxide reductase
A7K99_13300	ENOG4105D1F	ATP-binding protein
A7K99_13305	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A7K99_13310	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
A7K99_13315	ENOG4107R1I	NAD-dependent malic enzyme
A7K99_13325	ENOG4107SDZ	Galactoside transport system permease protein mglC
A7K99_13330	ENOG4105C2J	ABC transporter
A7K99_13340	ENOG4105DHF	Membrane
A7K99_13345	ENOG4105EUJ	GTP cyclohydrolase i
A7K99_13350	ENOG4105EGI	Transcriptional regulator
A7K99_13360	ENOG4108IQI	permease
A7K99_13365	ENOG4105DUM	transcriptional regulator, lysR family
A7K99_13370	ENOG4105HMI	Membrane
A7K99_13380	ENOG4105DM4	PTS System
A7K99_13385	ENOG4105DE4	1-phosphofructokinase
A7K99_13390	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A7K99_13400	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A7K99_13405	ENOG41076MN	Phosphoesterase, PA-phosphatase related
A7K99_13410	ENOG4105VNT	transposase (IS4 family) protein
A7K99_13415	ENOG4107QTZ	amino acid
A7K99_13425	ENOG4107TT5	NLP P60 protein
A7K99_13435	ENOG4105C2C	drug resistance transporter, Bcr CflA
A7K99_13440	ENOG4105I08	Pseudouridine synthase
A7K99_13445	ENOG4105CFI	type iii restriction protein res subunit
A7K99_13450	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A7K99_13455	ENOG4106V8H	Nucleoid-associated protein
A7K99_13460	ENOG4105PAN	UPF0352 protein
A7K99_13465	ENOG4105E68	Sulfatase
A7K99_13475	ENOG4105Y50	Virulence Protein
A7K99_13480	ENOG4105XPP	Protein of unknown function (DUF1275)
A7K99_13485	ENOG4108SB3	DoxX Family
A7K99_13490	ENOG4105CC0	LysR family Transcriptional regulator
A7K99_13505	ENOG4105CF1	Alkylated DNA repair protein
A7K99_13510	ENOG4105CJ2	(LipO)protein
A7K99_13520	ENOG4105FCK	Membrane
A7K99_13530	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
A7K99_13535	ENOG41068CG	regulatoR
A7K99_13540	ENOG4105BZU	Histidine kinase
A7K99_13545	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A7K99_13550	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A7K99_13555	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A7K99_13560	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A7K99_13565	ENOG4105XPH	Ferredoxin
A7K99_13575	ENOG4107S37	Molybdopterin binding domain protein
A7K99_13590	ENOG4107YB6	acetyltransferase, (GNAT) family
A7K99_13595	ENOG4105CHR	reductase
A7K99_13600	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7K99_13605	ENOG4105C8S	subunit m
A7K99_13610	ENOG4105D65	subunit l
A7K99_13615	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7K99_13620	ENOG4107UFS	subunit j
A7K99_13625	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7K99_13630	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A7K99_13635	ENOG4107R0R	NADH dehydrogenase subunit g
A7K99_13640	ENOG4107QIZ	NADH dehydrogenase
A7K99_13645	ENOG4105GKE	subunit e
A7K99_13650	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7K99_13655	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7K99_13660	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A7K99_13665	ENOG4107NQ8	LysR family Transcriptional regulator
A7K99_13670	ENOG4105CHM	Aminotransferase
A7K99_13675	ENOG4105DK2	UPF0207 protein
A7K99_13680	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
A7K99_13685	ENOG4105PQ6	UPF0208 membrane protein
A7K99_13695	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A7K99_13700	ENOG4105C6K	Malic enzyme
A7K99_13705	ENOG4105PTV	Nudix Hydrolase
A7K99_13710	ENOG4108SHQ	Glutathione S-transferase
A7K99_13715	ENOG4108JEH	abc transporter atp-binding protein
A7K99_13720	ENOG4106YG3	ABC transporter
A7K99_13725	ENOG4105DSP	amino acid AbC transporter
A7K99_13730	ENOG4105E89	ABC transporter
A7K99_13735	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A7K99_13740	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A7K99_13745	ENOG4105E96	Colicin v production protein
A7K99_13750	ENOG4108S3P	Sporulation domain protein
A7K99_13755	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A7K99_13760	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A7K99_13765	ENOG4105DQR	SNARE associated Golgi
A7K99_13770	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A7K99_13775	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A7K99_13790	ENOG4106WZ1	flagella biosynthesis regulator
A7K99_13805	ENOG4105F9N	Major Facilitator Superfamily
A7K99_13810	ENOG4105CH2	amidohydrolase
A7K99_13815	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A7K99_13825	ENOG4105MH2	YfcL protein
A7K99_13830	ENOG4108BPE	-transporting atpase
A7K99_13835	ENOG4105EJ9	Membrane
A7K99_13845	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A7K99_13855	ENOG4108DG9	Smr protein MutS2
A7K99_13860	ENOG4108BY2	phosphohistidine phosphatase
A7K99_13865	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A7K99_13870	ENOG4105CHU	acetyl-coa acetyltransferase
A7K99_13875	ENOG4105KZW	UPF0381 protein
A7K99_13880	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A7K99_13885	ENOG410903C	(LipO)protein
A7K99_13890	ENOG4108M1T	Cytochrome c-type biogenesis protein
A7K99_13895	ENOG4108M1T	Cytochrome c-type biogenesis protein
A7K99_13905	ENOG4105DA4	cytochrome c-type biogenesis protein
A7K99_13915	ENOG4105X3C	heme exporter protein
A7K99_13920	ENOG41060IM	Heme exporter protein
A7K99_13925	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A7K99_13935	ENOG4105S64	Formate nitrite transporter
A7K99_13940	ENOG4105CC0	LysR family Transcriptional regulator
A7K99_13970	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A7K99_13975	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A7K99_13980	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A7K99_13985	ENOG4108ESZ	Glycogen debranching enzyme
A7K99_13990	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A7K99_14000	ENOG4105DKT	Transcriptional regulator
A7K99_14005	ENOG4105CP7	Triose-phosphate isomerase
A7K99_14010	ENOG4105CMT	Dihydroxyacetone kinase
A7K99_14015	ENOG4108YZG	isomerase
A7K99_14025	ENOG4105DJB	Major Facilitator Superfamily
A7K99_14030	ENOG4105C5I	Dehydrogenase
A7K99_14060	ENOG4105E5D	amino acid
A7K99_14065	ENOG4105CUB	amino acid
A7K99_14070	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A7K99_14085	ENOG4105C26	Dehydrogenase
A7K99_14095	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
A7K99_14100	ENOG4108JJ8	(ABC) transporter
A7K99_14105	ENOG4108JJ9	ABC, transporter
A7K99_14115	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A7K99_14145	ENOG4105FCD	Major Facilitator
A7K99_14170	ENOG4105CHM	Aminotransferase
A7K99_14175	ENOG4108HRK	Histidine kinase
A7K99_14180	ENOG4105DY9	regulatoR
A7K99_14185	ENOG4105CHC	glucokinase (EC 2.7.1.2)
A7K99_14195	ENOG4105D9N	nucleoside
A7K99_14205	ENOG4105F4G	Membrane
A7K99_14220	ENOG4105HZG	regulatoR
A7K99_14225	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A7K99_14265	ENOG4105D9R	oxidoreductase
A7K99_14270	ENOG4105E98	transcriptional regulator DeoR family
A7K99_14275	ENOG4105EW9	transcriptional regulator AsnC family
A7K99_14290	ENOG4108M0I	Transcriptional regulator
A7K99_14295	ENOG4105DHU	Bile acid
A7K99_14300	ENOG4105CW7	secretion protein, HlyD family
A7K99_14305	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A7K99_14315	ENOG4105VRT	cytoplasmic protein
A7K99_14320	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A7K99_14325	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
A7K99_14330	ENOG4105EXN	Sulfate transport protein CysZ
A7K99_14335	ENOG4105C6T	cysteine synthase
A7K99_14340	ENOG4105KZ7	phosphocarrier protein hpr
A7K99_14350	ENOG4105C5Y	PTS System
A7K99_14355	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A7K99_14360	ENOG4105CKK	Glycosyl transferase, family 2
A7K99_14370	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A7K99_14375	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A7K99_14390	ENOG4105E0F	Histidine kinase
A7K99_14395	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A7K99_14400	ENOG4105C6T	cysteine synthase
A7K99_14410	ENOG4105ECW	sulfate abc transporter
A7K99_14415	ENOG4108I5D	sulfate abc transporter
A7K99_14420	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
A7K99_14425	ENOG4105EZR	dyp-type peroxidase family protein
A7K99_14430	ENOG4105E7K	(LipO)protein
A7K99_14435	ENOG4105QZU	Inner membrane protein YfeZ
A7K99_14440	ENOG4108R6G	acetyltransferase
A7K99_14445	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
A7K99_14455	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A7K99_14460	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A7K99_14465	ENOG4107R6D	beta-lactam binding protein AmpH
A7K99_14475	ENOG4105C85	amino acid
A7K99_14480	ENOG4105KUZ	arsenate reductase
A7K99_14485	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A7K99_14490	ENOG4105XYK	UPF0370 protein
A7K99_14495	ENOG4106KED	esterase YpfH
A7K99_14500	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A7K99_14505	ENOG4105CGZ	zinc metallopeptidase
A7K99_14515	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A7K99_14525	ENOG4105RH4	Glycine cleavage system transcriptional repressor
A7K99_14530	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7K99_14535	ENOG4105ERG	peptidase m48, ste24p
A7K99_14540	ENOG4105K89	arsenate reductase
A7K99_14545	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
A7K99_14550	ENOG4105C2W	permease
A7K99_14560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A7K99_14565	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A7K99_14570	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A7K99_14575	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A7K99_14580	ENOG4105C9X	ppx gppa phosphatase
A7K99_14585	ENOG41088CC	tellurite resistance protein tehB
A7K99_14590	ENOG4105CJW	magnesium transporter
A7K99_14595	ENOG4105DZG	Dehydrogenase
A7K99_14630	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
A7K99_14635	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A7K99_14645	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A7K99_14650	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A7K99_14660	ENOG4108MGI	Transcriptional regulator
A7K99_14665	ENOG4105C57	major facilitator superfamily
A7K99_14675	ENOG4105CHR	reductase
A7K99_14690	ENOG4108IXY	short-chain dehydrogenase reductase
A7K99_14695	ENOG4105CF7	AraC family transcriptional regulator
A7K99_14700	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A7K99_14730	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A7K99_14755	ENOG4108V06	Glutathione peroxidase
A7K99_14765	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A7K99_14770	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A7K99_14775	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A7K99_14785	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A7K99_14790	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A7K99_14795	ENOG4105N21	Membrane
A7K99_14800	ENOG4105CUT	histidyl-tRNA synthetase
A7K99_14805	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A7K99_14820	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A7K99_14825	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A7K99_14830	ENOG4105KHC	sulfurtransferase
A7K99_14835	ENOG4105YYA	enhanced serine sensitivity protein SseB
A7K99_14845	ENOG4105WVQ	Fe-S assembly protein IscX
A7K99_14850	ENOG4108ZIT	Ferredoxin, 2FE-2S
A7K99_14855	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A7K99_14860	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A7K99_14870	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A7K99_14880	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A7K99_14885	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A7K99_14895	ENOG4108MN2	Stationary phase inducible protein CsiE
A7K99_14900	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A7K99_14905	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A7K99_14910	ENOG4108YZA	Nitrogen regulatory protein pii
A7K99_14915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A7K99_14925	ENOG4107WP9	Histidine kinase
A7K99_14930	ENOG4105VNT	transposase (IS4 family) protein
A7K99_14935	ENOG4108ETH	Formylglycinamide ribotide synthetase
A7K99_14940	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A7K99_14945	ENOG4108Z6B	deaminase
A7K99_14975	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
A7K99_14985	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A7K99_14990	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A7K99_14995	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A7K99_15000	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
A7K99_15005	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A7K99_15010	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A7K99_15015	ENOG4105C3F	Signal peptidase i
A7K99_15020	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A7K99_15025	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
A7K99_15045	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A7K99_15050	ENOG4105C1J	atp-dependent rna helicase
A7K99_15055	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
A7K99_15065	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A7K99_15070	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A7K99_15075	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A7K99_15080	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A7K99_15085	ENOG4105VDB	UPF0125 protein
A7K99_15090	ENOG4108Z1B	Cyclase dehydrase
A7K99_15110	ENOG4105H38	Membrane
A7K99_15145	ENOG4105CKT	filamentous hemagglutinin
A7K99_15150	ENOG4105D5K	Hemolysin activator protein
A7K99_15175	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A7K99_15195	ENOG4105DT3	PTS system, galactitol-specific IIc component
A7K99_15205	ENOG4108WS1	
A7K99_15210	ENOG4108KHX	Diguanylate cyclase
A7K99_15215	ENOG41090EK	ompa motb domain protein
A7K99_15220	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
A7K99_15225	ENOG4105KVH	Transcriptional regulator
A7K99_15245	ENOG4105E0C	molybdate abc transporter
A7K99_15250	ENOG41066FR	extracellular solute-binding protein
A7K99_15255	ENOG4105W1Y	Transcriptional regulator
A7K99_15275	ENOG4108JDX	DNA polymerase iii, epsilon subunit
A7K99_15285	ENOG4105D1A	Methyltransferase
A7K99_15290	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A7K99_15295	ENOG4105E9H	Lytic Murein transglycosylase
A7K99_15300	ENOG4107NA1	Endonuclease Exonuclease phosphatase
A7K99_15305	ENOG4105F27	Major Facilitator
A7K99_15310	ENOG4105HEI	LysR family (Transcriptional regulator
A7K99_15315	ENOG4105CV8	reductase
A7K99_15320	ENOG4106FTQ	Taurine ABC transporter, periplasmic
A7K99_15330	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A7K99_15335	ENOG4105E2B	Taurine dioxygenase
A7K99_15340	ENOG4107QNK	)-transporter
A7K99_15375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A7K99_15380	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A7K99_15385	ENOG4105C34	Pseudouridine synthase
A7K99_15390	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7K99_15395	ENOG4105VNT	transposase (IS4 family) protein
A7K99_15400	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
A7K99_15415	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A7K99_15420	ENOG4105E89	ABC transporter
A7K99_15425	ENOG4105CHM	Aminotransferase
A7K99_15430	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
A7K99_15440	ENOG4106PMH	Extracellular solute-binding protein family 3
A7K99_15445	ENOG4105E5Q	amino acid AbC transporter
A7K99_15450	ENOG4105CDA	abc transporter atp-binding protein
A7K99_15465	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A7K99_15470	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A7K99_15475	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
A7K99_15480	ENOG4105V1F	Fermentation respiration switch protein
A7K99_15485	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A7K99_15490	ENOG4105CIN	aminoacyl-histidine dipeptidase
A7K99_15505	ENOG4105CNN	ABC, transporter
A7K99_15510	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A7K99_15515	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
A7K99_15520	ENOG4105E7A	Glutamine amidotransferase
A7K99_15525	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A7K99_15530	ENOG4107QPN	acyl-Coa dehydrogenase
A7K99_15535	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
A7K99_15545	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
A7K99_15550	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
A7K99_15555	ENOG4105CHM	Aminotransferase
A7K99_15560	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A7K99_15565	ENOG4105VT2	5-hydroxyisourate hydrolase
A7K99_15580	ENOG4105C5R	Aminotransferase
A7K99_15585	ENOG4106PMH	Extracellular solute-binding protein family 3
A7K99_15595	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A7K99_15620	ENOG4108MK9	spermidine N(1)-acetyltransferase
A7K99_15625	ENOG4108WMJ	Protein of unknown function (DUF2002)
A7K99_15630	ENOG4105NE1	Conserved Protein
A7K99_15640	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
A7K99_15645	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A7K99_15650	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A7K99_15655	ENOG4108IJ7	Glycine betaine
A7K99_15660	ENOG4108HQS	Glycine betaine
A7K99_15665	ENOG4105GIJ	Glycine betaine
A7K99_15670	ENOG4105NTK	Transcriptional repressor Mpra
A7K99_15675	ENOG4105CW7	secretion protein, HlyD family
A7K99_15680	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A7K99_15685	ENOG4105EIB	trna rrna methyltransferase
A7K99_15690	ENOG4105K63	Thioredoxin
A7K99_15695	ENOG4106IUH	DTW domain containing protein
A7K99_15700	ENOG4105CD5	CoA-binding domain protein
A7K99_15705	ENOG4105JIM	Phosphatidylserine synthase
A7K99_15720	ENOG4105CSH	Transporter
A7K99_15750	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A7K99_15760	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_15765	ENOG4108UMI	ABC transporter, permease
A7K99_15770	ENOG4105D01	(LipO)protein
A7K99_15775	ENOG4108R8X	outer membrane lipoprotein
A7K99_15780	ENOG4108R96	Methyltransferase, YaeB family
A7K99_15785	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A7K99_15790	ENOG4108YZN	class I peptide chain release factor
A7K99_15795	ENOG4108VWS	Yaeq family
A7K99_15800	ENOG4105M1T	rho-binding antiterminator
A7K99_15805	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A7K99_15810	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A7K99_15815	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A7K99_15820	ENOG4105C0B	DNA polymerase III (alpha subunit)
A7K99_15825	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A7K99_15830	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A7K99_15835	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A7K99_15840	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A7K99_15850	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
A7K99_15855	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7K99_15865	ENOG4105KNE	Phosphatidate cytidylyltransferase
A7K99_15870	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A7K99_15875	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A7K99_15880	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A7K99_15885	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A7K99_15890	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A7K99_15900	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A7K99_15905	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A7K99_15910	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A7K99_15915	ENOG4108T8E	UPF0325 protein
A7K99_15920	ENOG4105C0H	protease
A7K99_15925	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A7K99_15930	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A7K99_15935	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A7K99_15940	ENOG4105CMQ	Chloride channel
A7K99_15950	ENOG4105BZ4	penicillin-binding protein
A7K99_15955	ENOG4105CQ7	ATP-dependent helicase
A7K99_15965	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A7K99_15970	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7K99_15975	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A7K99_15980	ENOG4105DJ0	Poly(A) Polymerase
A7K99_15985	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7K99_15990	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A7K99_15995	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A7K99_16000	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
A7K99_16005	ENOG4105E3A	(ABC) transporter
A7K99_16010	ENOG4105DA5	(ABC) transporter
A7K99_16015	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A7K99_16020	ENOG4105E3B	Multicopper oxidase
A7K99_16025	ENOG4108ZRK	uncharacterized protein yacC
A7K99_16030	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A7K99_16035	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A7K99_16040	ENOG4108ZIG	UPF0231 protein
A7K99_16045	ENOG4107QIJ	Aconitate hydratase 2
A7K99_16055	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A7K99_16060	ENOG4107QN2	dihydrolipoyl dehydrogenase
A7K99_16065	ENOG4107QSN	dihydrolipoamide acetyltransferase
A7K99_16070	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A7K99_16075	ENOG41073TP	transcriptional regulator
A7K99_16080	ENOG4105C85	amino acid
A7K99_16085	ENOG4106A72	regulatory protein AmpE
A7K99_16090	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A7K99_16095	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A7K99_16100	ENOG4108ZUW	Major pilin subunit
A7K99_16105	ENOG4107QHF	type ii secretion system protein e
A7K99_16110	ENOG4105D7Q	type ii secretion system
A7K99_16115	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A7K99_16120	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A7K99_16130	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A7K99_16135	ENOG4105M6F	mutator MutT protein
A7K99_16145	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
A7K99_16150	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A7K99_16155	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A7K99_16160	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A7K99_16165	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
A7K99_16170	ENOG4105CPF	Cell wall formation (By similarity)
A7K99_16175	ENOG4105DFU	Cell wall formation (By similarity)
A7K99_16180	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A7K99_16185	ENOG4105CNI	cell division protein FtsW
A7K99_16190	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A7K99_16195	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A7K99_16200	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A7K99_16205	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A7K99_16210	ENOG4105CJN	penicillin-binding protein
A7K99_16215	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A7K99_16220	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A7K99_16225	ENOG4108V6E	Cell division protein mraZ
A7K99_16230	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
A7K99_16235	ENOG4108ZP8	Acetolactate synthase small subunit
A7K99_16240	ENOG4105C7K	acetolactate synthase
A7K99_16245	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A7K99_16255	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A7K99_16260	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A7K99_16265	ENOG4105S8Q	sugar efflux transporter
A7K99_16275	ENOG4105DP9	ABC transporter
A7K99_16280	ENOG4106SMU	thiamine transporter membrane protein
A7K99_16290	ENOG4108KF1	Membrane
A7K99_16295	ENOG4105CQ2	DNA polymerase
A7K99_16300	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A7K99_16305	ENOG4105D3G	Pseudouridine synthase
A7K99_16310	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A7K99_16315	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A7K99_16325	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A7K99_16330	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A7K99_16335	ENOG4105NWN	ApaG protein
A7K99_16340	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A7K99_16345	ENOG4105CS2	ec 3.2.1.21
A7K99_16355	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A7K99_16370	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A7K99_16375	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A7K99_16380	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A7K99_16385	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A7K99_16390	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A7K99_16395	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A7K99_16400	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A7K99_16405	ENOG4105DTN	riboflavin biosynthesis protein ribF
A7K99_16410	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A7K99_16415	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A7K99_16420	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A7K99_16435	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A7K99_16445	ENOG4105D1Q	UPF0246 protein
A7K99_16450	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
A7K99_16465	ENOG4105CFH	Aspartokinase
A7K99_16470	ENOG4106FVC	RNA methyltransferase
A7K99_16475	ENOG41065U4	response regulator
A7K99_16480	ENOG4108RH0	Crea protein
A7K99_16485	ENOG4105UEI	Transcriptional Regulator AraC Family
A7K99_16495	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A7K99_16505	ENOG4107SC1	transglycosylase
A7K99_16515	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A7K99_16530	ENOG4105C32	Amino acid ABC transporter (Permease)
A7K99_16535	ENOG4105CNN	ABC, transporter
A7K99_16540	ENOG4105C0Z	ABC transporter
A7K99_16545	ENOG4108IV0	ABC, transporter
A7K99_16560	ENOG4108RNG	Permease of the drug metabolite transporter
A7K99_16565	ENOG4105C5H	ABC transporter
A7K99_16570	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
A7K99_16575	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A7K99_16580	ENOG4105EAC	phosphoserine phosphatase
A7K99_16585	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
A7K99_16595	ENOG4105C26	Dehydrogenase
A7K99_16605	ENOG4105EGI	Transcriptional regulator
A7K99_16610	ENOG4105PAD	Hydrolase
A7K99_16615	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A7K99_16620	ENOG4108WPU	DNA polymerase III subunit psi
A7K99_16655	ENOG4108UIN	ybak prolyl-trna synthetase associated region
A7K99_16660	ENOG4105JHE	Major Facilitator Superfamily
A7K99_16670	ENOG4108Z1S	Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly
A7K99_16685	ENOG4105C32	Amino acid ABC transporter (Permease)
A7K99_16690	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A7K99_16695	ENOG4105C0Z	ABC transporter
A7K99_16700	ENOG4108IV0	ABC, transporter
A7K99_16705	ENOG4105CPU	Monooxygenase
A7K99_16715	ENOG4108XSB	acetyltransferase, (GNAT) family
A7K99_16720	ENOG4105CH2	amidohydrolase
A7K99_16725	ENOG4108PGP	mmge prpd family protein
A7K99_16735	ENOG4105CDA	abc transporter atp-binding protein
A7K99_16750	ENOG4105C5I	Dehydrogenase
A7K99_16760	ENOG4105E89	ABC transporter
A7K99_16765	ENOG4105CDA	abc transporter atp-binding protein
A7K99_16770	ENOG4105C5Q	Transcriptional regulator
A7K99_16775	ENOG4105CWC	Acetylornithine deacetylase
A7K99_16785	ENOG4105KME	endoribonuclease L-psp
A7K99_16790	ENOG4106V2I	dimethylaminohydrolase
A7K99_16800	ENOG4108JPW	Aminotransferase
A7K99_16810	ENOG4105C26	Dehydrogenase
A7K99_16815	ENOG4106WTF	Glycosyl transferase, family 2
A7K99_16830	ENOG4108IU3	tonb-dependent siderophore receptor
A7K99_16840	ENOG4105CPF	Cell wall formation (By similarity)
A7K99_16845	ENOG4105BZU	Histidine kinase
A7K99_16850	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
A7K99_16855	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A7K99_16860	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_16865	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A7K99_16875	ENOG4105DU1	integral membrane protein, terc
A7K99_16880	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
A7K99_16885	ENOG4106W5V	Membrane
A7K99_16890	ENOG4105VD9	Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity)
A7K99_16895	ENOG4105WAY	exported protein
A7K99_16900	ENOG4105NE1	Conserved Protein
A7K99_16905	ENOG41090KG	Inner membrane protein YqjE
A7K99_16915	ENOG4105CHF	Glutathione S-transferase
A7K99_16920	ENOG4105CWB	LysR family transcriptional Regulator
A7K99_16925	ENOG4108CNN	domain protein
A7K99_16930	ENOG4105W4M	Transport-associated protein
A7K99_16945	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A7K99_16950	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A7K99_16960	ENOG4106KR7	LysR family Transcriptional regulator
A7K99_16965	ENOG4105GVF	(ABC) transporter
A7K99_16970	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A7K99_16995	ENOG4105MP9	class II Aldolase
A7K99_17000	ENOG4108XVM	Cytochrome b(562)
A7K99_17005	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A7K99_17010	ENOG4105N42	UPF0307 protein
A7K99_17015	ENOG4105DFU	Cell wall formation (By similarity)
A7K99_17020	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A7K99_17025	ENOG4105C8Q	Methyl-accepting chemotaxis
A7K99_17030	ENOG4105F0N	pyrophosphate phospho-hydrolase
A7K99_17035	ENOG4108ZHD	aig2 family
A7K99_17045	ENOG4105CFU	surface antigen
A7K99_17050	ENOG4105C37	(CBS) domain
A7K99_17055	ENOG41061GZ	Protein of unknown function (DUF1107)
A7K99_17060	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A7K99_17065	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A7K99_17070	ENOG4105FHY	Opacity-associated protein A
A7K99_17075	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A7K99_17080	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A7K99_17085	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
A7K99_17090	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A7K99_17095	ENOG4108WN0	inhibitor of vertebrate lysozyme
A7K99_17105	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A7K99_17110	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A7K99_17120	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A7K99_17130	ENOG4105EPW	hflc protein
A7K99_17135	ENOG4107QJR	hflk protein
A7K99_17140	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A7K99_17150	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A7K99_17155	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A7K99_17160	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A7K99_17165	ENOG4105K8N	protein family UPF0079, ATPase
A7K99_17170	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A7K99_17175	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A7K99_17185	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_17210	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A7K99_17220	ENOG4105DJ4	phosphatidylserine decarboxylase
A7K99_17225	ENOG4105EGS	Mechanosensitive ion channel
A7K99_17230	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A7K99_17235	ENOG4106BSU	Entericidin B
A7K99_17240	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A7K99_17245	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A7K99_17255	ENOG4108ZVF	(LipO)protein
A7K99_17260	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A7K99_17265	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A7K99_17270	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
A7K99_17275	ENOG4108IJ0	Aspartate ammonia-lyase
A7K99_17290	ENOG4108SIC	Transcriptional regulator
A7K99_17295	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A7K99_17300	ENOG4108IJ6	ABC transporter
A7K99_17310	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
A7K99_17320	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_17335	ENOG4105T40	surface antigen msp4 family protein
A7K99_17345	ENOG4105DEN	Luciferase family
A7K99_17360	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_17365	ENOG4105DEN	Luciferase family
A7K99_17375	ENOG4105EJC	lysr family transcriptional regulator
A7K99_17380	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A7K99_17385	ENOG4105F27	Major Facilitator
A7K99_17410	ENOG4105HEI	LysR family (Transcriptional regulator
A7K99_17430	ENOG4105HEI	LysR family (Transcriptional regulator
A7K99_17435	ENOG4105CSH	Transporter
A7K99_17460	ENOG4108UMI	ABC transporter, permease
A7K99_17465	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_17470	ENOG4105D01	(LipO)protein
A7K99_17485	ENOG4108UMI	ABC transporter, permease
A7K99_17490	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_17495	ENOG4105D01	(LipO)protein
A7K99_17515	ENOG4105E5Q	amino acid AbC transporter
A7K99_17520	ENOG4105E5Q	amino acid AbC transporter
A7K99_17535	ENOG4105CID	antiterminator
A7K99_17540	ENOG4105CS2	ec 3.2.1.21
A7K99_17545	ENOG4105C5Y	PTS System
A7K99_17560	ENOG4105EAB	amino acid AbC transporter
A7K99_17565	ENOG4105E5Q	amino acid AbC transporter
A7K99_17570	ENOG4105E5Q	amino acid AbC transporter
A7K99_17575	ENOG4108JEH	abc transporter atp-binding protein
A7K99_17580	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A7K99_17600	ENOG4105C2W	permease
A7K99_17605	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A7K99_17620	ENOG4105FXM	Copper resistance protein
A7K99_17630	ENOG4105CNN	ABC, transporter
A7K99_17635	ENOG4105C2J	ABC transporter
A7K99_17640	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
A7K99_17645	ENOG41062B0	ABC transporter, permease
A7K99_17650	ENOG4107R9N	ABC transporter
A7K99_17655	ENOG4105C2J	ABC transporter
A7K99_17660	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
A7K99_17675	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
A7K99_17690	ENOG4108FZ9	Chaperone
A7K99_17695	ENOG4105CW0	outer membrane usher protein
A7K99_17705	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
A7K99_17720	ENOG4105C6X	Major Facilitator
A7K99_17725	ENOG4105EJC	lysr family transcriptional regulator
A7K99_17735	ENOG4105DRB	nucleoside-specific channel-forming protein
A7K99_17740	ENOG4105C54	Major Facilitator superfamily
A7K99_17760	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
A7K99_17770	ENOG4108NS2	receptor
A7K99_17775	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A7K99_17780	ENOG4105CK2	sodium dicarboxylate symporter
A7K99_17785	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A7K99_17790	ENOG41062QD	Membrane
A7K99_17795	ENOG4107QN1	sodium solute
A7K99_17815	ENOG4105CMU	LysR family (Transcriptional regulator
A7K99_17820	ENOG4105EEQ	Na H antiporter
A7K99_17825	ENOG4108Z4X	TRANSCRIPTIONal
A7K99_17835	ENOG4105PMV	Membrane
A7K99_17850	ENOG4105DZG	Dehydrogenase
A7K99_17855	ENOG4107RA9	decarboxylase
A7K99_17860	ENOG4105DUM	transcriptional regulator, lysR family
A7K99_17885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A7K99_17890	ENOG4105DJ2	Major Facilitator Superfamily
A7K99_17905	ENOG4108DMH	HTH_ARAC
A7K99_17910	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A7K99_17930	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A7K99_17935	ENOG4105BZU	Histidine kinase
A7K99_17940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A7K99_17950	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A7K99_17955	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7K99_17980	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A7K99_17985	ENOG4105BZS	acriflavin resistance protein
A7K99_17990	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
A7K99_17995	ENOG4105DHQ	Histidine kinase
A7K99_18010	ENOG4105CMM	transposase
A7K99_18035	ENOG4108UUM	single-stranded DNA-binding protein
A7K99_18040	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A7K99_18045	ENOG4105DQ4	alcohol dehydrogenase
A7K99_18050	ENOG4105EQ2	LysR family Transcriptional regulator
A7K99_18055	ENOG4105CPC	Aldo Keto reductase
A7K99_18060	ENOG4105HEI	LysR family (Transcriptional regulator
A7K99_18065	ENOG41090U3	tautomerase
A7K99_18070	ENOG4105DDV	Transcriptional regulator (LacI family
A7K99_18075	ENOG4105CGF	Aromatic amino acid aminotransferase
A7K99_18085	ENOG4108XM1	transcriptional regulator AsnC family
A7K99_18090	ENOG4105CDU	Replicative dna helicase
A7K99_18095	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A7K99_18100	ENOG4105P4Z	Phage shock protein G
A7K99_18105	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A7K99_18120	ENOG4105MYN	Zinc uptake regulation protein
A7K99_18125	ENOG4107R73	Mate efflux family protein
A7K99_18130	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A7K99_18135	ENOG41080IJ	Diacylglycerol kinase
A7K99_18145	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A7K99_18150	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A7K99_18155	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
A7K99_18170	ENOG4105CFH	Aspartokinase
A7K99_18175	ENOG4105C09	Bile acid
A7K99_18180	ENOG4105EAM	Na Pi-cotransporter
A7K99_18185	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A7K99_18215	ENOG4105CPC	Aldo Keto reductase
A7K99_18220	ENOG4105CVG	Homoserine O-transsuccinylase
A7K99_18235	ENOG4105E89	ABC transporter
A7K99_18240	ENOG4105VNT	transposase (IS4 family) protein
A7K99_18285	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A7K99_18290	ENOG4105C12	Phosphoribosylglycinamide synthetase
A7K99_18295	ENOG4105VNT	transposase (IS4 family) protein
A7K99_18300	ENOG4108T8B	Protein of unknown function (DUF1481)
A7K99_18305	ENOG4105K70	DNA-binding protein
A7K99_18310	ENOG4105R2J	Conserved Protein
A7K99_18315	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A7K99_18320	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A7K99_18325	ENOG4105E09	nadh pyrophosphatase
A7K99_18330	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A7K99_18335	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A7K99_18340	ENOG4105D06	uba thif-type nad fad binding protein
A7K99_18345	ENOG4105WHD	thiamine biosynthesis protein ThiS
A7K99_18350	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A7K99_18355	ENOG4105D41	biosynthesis protein thiH
A7K99_18360	ENOG4108PVD	exported protein
A7K99_18370	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A7K99_18380	ENOG4108VZM	50s ribosomal protein L10
A7K99_18385	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A7K99_18390	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A7K99_18395	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A7K99_18400	ENOG4105PM1	preprotein translocase subunit SecE
A7K99_18405	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A7K99_18430	ENOG4105CS9	pantothenic acid kinase
A7K99_18435	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A7K99_18440	ENOG4105D4A	Cell wall formation (By similarity)
A7K99_18465	ENOG4108RR8	protoporphyrinogen oxidase
A7K99_18470	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A7K99_18475	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A7K99_18485	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A7K99_18490	ENOG4105CHU	acetyl-coa acetyltransferase
A7K99_18495	ENOG4107QK7	reductase
A7K99_18505	ENOG4105MDZ	Transcriptional activator rfaH
A7K99_18510	ENOG4105F8V	Hydrolase, tatD family
A7K99_18515	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A7K99_18525	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A7K99_18530	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A7K99_18535	ENOG4105JC1	sterol-binding domain protein
A7K99_18540	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A7K99_18545	ENOG4105CGY	Dna recombination protein
A7K99_18550	ENOG4108I5U	Uridine phosphorylase
A7K99_18555	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
A7K99_18565	ENOG4105FE9	pseudouridine synthase
A7K99_18570	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A7K99_18575	ENOG4105DZ2	Transcriptional regulator
A7K99_18580	ENOG4105CXY	transporter
A7K99_18585	ENOG4105DQF	Hydrolase
A7K99_18590	ENOG4108EUD	Lysophospholipase
A7K99_18595	ENOG410829K	Lysine exporter protein (Lyse ygga)
A7K99_18605	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A7K99_18610	ENOG4105HDD	phospholipase
A7K99_18615	ENOG4108VUY	thioesterase Superfamily protein
A7K99_18625	ENOG4105DJB	Major Facilitator Superfamily
A7K99_18630	ENOG4105EGI	Transcriptional regulator
A7K99_18635	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A7K99_18645	ENOG410642W	LysR family Transcriptional regulator
A7K99_18655	ENOG4107QUT	magnesium and cobalt transport protein CorA
A7K99_18660	ENOG4105C4R	Atp-dependent dna helicase
A7K99_18665	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
A7K99_18675	ENOG4105CT0	Protein of unknown function, DUF484
A7K99_18680	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A7K99_18685	ENOG4105S7Z	(LipO)protein
A7K99_18695	ENOG4107T0K	Adenylate cyclase
A7K99_18700	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A7K99_18705	ENOG41076E6	Uroporphyrinogen-III Synthase
A7K99_18710	ENOG4105ECF	c-methyltransferase
A7K99_18715	ENOG410601J	HemY protein
A7K99_18730	ENOG4108Z7R	Chaperone CsaA
A7K99_18765	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A7K99_18770	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
A7K99_18775	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
A7K99_18780	ENOG4105EGZ	biosynthesis protein
A7K99_18785	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A7K99_18790	ENOG4108WJ1	acetyltransferase
A7K99_18795	ENOG4108IJ1	Dehydrogenase
A7K99_18800	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A7K99_18805	ENOG4105SFE	lipopolysaccharide biosynthesis protein
A7K99_18810	ENOG4105ESV	Glycosyl transferase, family 4
A7K99_18820	ENOG4105K63	Thioredoxin
A7K99_18825	ENOG4105C1J	atp-dependent rna helicase
A7K99_18830	ENOG4105C9X	ppx gppa phosphatase
A7K99_18835	ENOG4105C4R	Atp-dependent dna helicase
A7K99_18840	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
A7K99_18845	ENOG4105CS0	peptidase
A7K99_18850	ENOG4108IND	Tetr family transcriptional regulator
A7K99_18860	ENOG4105BZU	Histidine kinase
A7K99_18865	ENOG4108JQ7	(ABC) transporter
A7K99_18870	ENOG4105C3U	ABC transporter
A7K99_18875	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A7K99_18880	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A7K99_18885	ENOG4105DEF	Extracellular solute-binding protein, family 5
A7K99_18910	ENOG4106JH6	(LipO)protein
A7K99_18915	ENOG4105J5J	Outer membrane porin
A7K99_18920	ENOG4108YYI	Protein of unknown function (DUF2810)
A7K99_18925	ENOG4108MJ5	VirK protein
A7K99_18930	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A7K99_18935	ENOG4108JPW	Aminotransferase
A7K99_18940	ENOG4105E98	transcriptional regulator DeoR family
A7K99_18950	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A7K99_18955	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A7K99_18975	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A7K99_18980	ENOG4105I5W	Transporter
A7K99_18985	ENOG4105D7T	ABC transporter
A7K99_19000	ENOG41075H3	AraC family transcriptional regulator
A7K99_19015	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A7K99_19020	ENOG4107QKS	N-acylglucosamine 2-epimerase
A7K99_19025	ENOG4108W15	Protein of unknown function (DUF1456)
A7K99_19035	ENOG4105DEN	Luciferase family
A7K99_19040	ENOG4105FF2	Type I DHQase
A7K99_19050	ENOG4106JPM	3-dehydroshikimate dehydratase
A7K99_19055	ENOG4108UQV	Membrane
A7K99_19060	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A7K99_19065	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A7K99_19070	ENOG4106NZI	LysR family Transcriptional regulator
A7K99_19075	ENOG4108IQI	permease
A7K99_19080	ENOG4107QK5	Homocysteine s-methyltransferase
A7K99_19095	ENOG4105EHG	Permease protein
A7K99_19115	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A7K99_19135	ENOG4108ZJF	Glcg protein
A7K99_19150	ENOG4108UMN	azlc family
A7K99_19160	ENOG4105CNN	ABC, transporter
A7K99_19170	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A7K99_19175	ENOG4105CMG	Carbohydrate kinase
A7K99_19180	ENOG4105DEI	Mannitol dehydrogenase
A7K99_19190	ENOG4105CFM	UPF0317 protein
A7K99_19195	ENOG4105CSH	Transporter
A7K99_19205	ENOG4105P4J	Allophanate hydrolase, subunit 1
A7K99_19215	ENOG4108M0I	Transcriptional regulator
A7K99_19220	ENOG4105DND	Transcriptional regulator
A7K99_19225	ENOG41074DU	domain protein
A7K99_19230	ENOG4108P2H	Inner membrane protein YjiG
A7K99_19240	ENOG4107WN4	Polygalacturonase
A7K99_19250	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
A7K99_19260	ENOG4105D5Q	Arginine ornithine antiporter
A7K99_19270	ENOG4105D5Q	Arginine ornithine antiporter
A7K99_19275	ENOG4105CUT	histidyl-tRNA synthetase
A7K99_19295	ENOG4105ETT	transcriptional Regulator, LysR family
A7K99_19300	ENOG4105CSH	Transporter
A7K99_19305	ENOG4107U9B	transcriptional regulator
A7K99_19310	ENOG4108VW9	Membrane
A7K99_19325	ENOG4105UEI	Transcriptional Regulator AraC Family
A7K99_19335	ENOG4108V1U	phospholipid-binding protein
A7K99_19350	ENOG410642W	LysR family Transcriptional regulator
A7K99_19355	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A7K99_19360	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A7K99_19365	ENOG4105CSW	GntR family transcriptional regulator
A7K99_19370	ENOG4105CBX	hi0933 family
A7K99_19375	ENOG4105CJ3	phosphate transporter
A7K99_19380	ENOG4105C5R	Aminotransferase
A7K99_19385	ENOG4105CDA	abc transporter atp-binding protein
A7K99_19390	ENOG4105E5Q	amino acid AbC transporter
A7K99_19395	ENOG4105E5Q	amino acid AbC transporter
A7K99_19415	ENOG41080HI	glycine oxidase
A7K99_19425	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
A7K99_19435	ENOG4108WYP	Transcriptional regulator
A7K99_19440	ENOG4108V6B	universal stress protein B
A7K99_19445	ENOG4108M6U	Universal stress protein A
A7K99_19450	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A7K99_19455	ENOG4105DGW	oligopeptidase A
A7K99_19460	ENOG4105D6S	protein involved in catabolism of external DNA
A7K99_19465	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A7K99_19470	ENOG4105DC8	reductase
A7K99_19475	ENOG4108Z6Z	Transcriptional regulator
A7K99_19480	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A7K99_19485	ENOG4105EVZ	LysR family transcriptional regulator
A7K99_19490	ENOG4105D4T	Citrate transporter
A7K99_19505	ENOG4105D0C	transport protein
A7K99_19515	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A7K99_19520	ENOG4105E0K	tonB-dependent siderophore receptor
A7K99_19530	ENOG4105EQ0	Major Facilitator superfamily
A7K99_19535	ENOG4105CR8	Transcriptional regulator
A7K99_19545	ENOG4108TEB	UPF0114 protein
A7K99_19565	ENOG4105BZ1	(ABC) transporter
A7K99_19570	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A7K99_19580	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A7K99_19590	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A7K99_19600	ENOG4108JQ6	ABC transporter
A7K99_19610	ENOG41082CG	Protein CrcB homolog
A7K99_19615	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
A7K99_19620	ENOG4105WQ6	Membrane
A7K99_19630	ENOG4108TGY	Glutathione S-transferase
A7K99_19635	ENOG4107H3J	ribonuclease
A7K99_19645	ENOG4105CSH	Transporter
A7K99_19650	ENOG410829K	Lysine exporter protein (Lyse ygga)
A7K99_19655	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A7K99_19660	ENOG4105EMY	transcriptional regulator
A7K99_19665	ENOG4105C7B	Threonine dehydratase
A7K99_19670	ENOG4105C01	Dihydroxy-acid dehydratase
A7K99_19675	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A7K99_19680	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
A7K99_19690	ENOG4105C0P	Mg chelatase subunit ChlI
A7K99_19695	ENOG4108WFC	UPF0438 protein yifE
A7K99_19700	ENOG4105CVI	Transcriptional regulator
A7K99_19740	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
A7K99_19745	ENOG4108Y73	Membrane
A7K99_19750	ENOG4105EJ2	Transcriptional regulator
A7K99_19755	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
A7K99_19760	ENOG4105C5Q	Transcriptional regulator
A7K99_19765	ENOG4105EHV	domain protein
A7K99_19775	ENOG4105CDH	Citrulline--aspartate ligase
A7K99_19780	ENOG4105CAS	nag kinase
A7K99_19785	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A7K99_19790	ENOG4105CWC	Acetylornithine deacetylase
A7K99_19795	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A7K99_19800	ENOG4105SYT	Methylenetetrahydrofolate reductase
A7K99_19805	ENOG4105CFH	Aspartokinase
A7K99_19810	ENOG4105C28	cystathionine
A7K99_19815	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A7K99_19820	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A7K99_19825	ENOG4105C25	Primosomal protein n'
A7K99_19830	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_19835	ENOG41063M6	Cell Division Protein
A7K99_19840	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A7K99_19850	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A7K99_19855	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
A7K99_19860	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A7K99_19870	ENOG4105CBT	Fructose-1,6-bisphosphatase
A7K99_19875	ENOG4105E5M	Multidrug resistance protein D
A7K99_19880	ENOG4105DP0	ferredoxin-NADP reductase
A7K99_19885	ENOG4105EBK	exported protein
A7K99_19890	ENOG4105CP7	Triose-phosphate isomerase
A7K99_19895	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
A7K99_19900	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A7K99_19905	ENOG4105CTQ	phosphohexokinase
A7K99_19910	ENOG41076HS	cation diffusion facilitator family transporter
A7K99_19915	ENOG4108ZI2	Fimbrial protein
A7K99_19925	ENOG4105CW0	outer membrane usher protein
A7K99_19930	ENOG4108AF8	Chaperone
A7K99_19935	ENOG4108WDE	Fimbrial protein
A7K99_19940	ENOG4108TC1	Transcriptional regulator
A7K99_19950	ENOG4105FMW	periplasmic
A7K99_19955	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A7K99_19960	ENOG4105E0F	Histidine kinase
A7K99_19965	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A7K99_19970	ENOG4105D7W	serine acetyltransferase
A7K99_19975	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A7K99_19980	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A7K99_19985	ENOG4105VW4	glutaredoxin 3
A7K99_19990	ENOG4107YZP	Rhodanese domain protein
A7K99_19995	ENOG41063SB	peptidase
A7K99_20000	ENOG4105PXI	polysaccharide deacetylase
A7K99_20005	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
A7K99_20010	ENOG4105XA0	heptosyltransferase ii
A7K99_20015	ENOG4105D16	lipopolysaccharide heptosyltransferase i
A7K99_20025	ENOG41068PG	O-Antigen polymerase
A7K99_20035	ENOG4105CPK	Glycosyl transferase (Group 1
A7K99_20040	ENOG4105DKP	glycosyl transferase, family 9
A7K99_20045	ENOG4105DKP	glycosyl transferase, family 9
A7K99_20050	ENOG4107RJ7	Glycosyl transferase (Group 1
A7K99_20055	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A7K99_20060	ENOG4106WTF	Glycosyl transferase, family 2
A7K99_20065	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A7K99_20070	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A7K99_20075	ENOG4105W0E	50S ribosomal protein L33
A7K99_20080	ENOG4105KDC	50s ribosomal protein l28
A7K99_20085	ENOG4105W5Q	DNA repair protein (RadC
A7K99_20090	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A7K99_20100	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A7K99_20105	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A7K99_20110	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A7K99_20115	ENOG4105D9N	nucleoside
A7K99_20125	ENOG4105DSJ	YicC domain protein
A7K99_20130	ENOG4105K56	Transcriptional regulator
A7K99_20140	ENOG4105C2M	dna polymerase I
A7K99_20155	ENOG4105E27	serine threonine protein kinase
A7K99_20160	ENOG4105PC1	Conserved Protein
A7K99_20165	ENOG4105VNT	transposase (IS4 family) protein
A7K99_20170	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A7K99_20175	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
A7K99_20205	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A7K99_20210	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_20215	ENOG4108RVA	ribokinase
A7K99_20220	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A7K99_20225	ENOG4105CNN	ABC, transporter
A7K99_20230	ENOG4105C2J	ABC transporter
A7K99_20245	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
A7K99_20250	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
A7K99_20255	ENOG4108VVK	transcriptional Regulator, AsnC
A7K99_20260	ENOG4105QTB	Flavodoxin
A7K99_20265	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A7K99_20270	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A7K99_20275	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
A7K99_20280	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A7K99_20285	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A7K99_20290	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A7K99_20295	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A7K99_20300	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A7K99_20305	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A7K99_20310	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A7K99_20325	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A7K99_20330	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A7K99_20335	ENOG4105E89	ABC transporter
A7K99_20350	ENOG4107DB1	DUF218 domain
A7K99_20355	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
A7K99_20360	ENOG4105EXG	Transcriptional regulator
A7K99_20390	ENOG4107NQ8	LysR family Transcriptional regulator
A7K99_20395	ENOG4107SVH	Potassium channel protein
A7K99_20460	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
A7K99_20470	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A7K99_20475	ENOG4105DG4	malate L-lactate dehydrogenase
A7K99_20485	ENOG4108RQP	Major type 1 subunit fimbrin
A7K99_20490	ENOG4108S54	Fimbrial protein
A7K99_20495	ENOG4108NAE	Fimbrial chaperone protein
A7K99_20500	ENOG4105CW0	outer membrane usher protein
A7K99_20505	ENOG4108SQA	Fimbrial
A7K99_20510	ENOG4108T65	Fimbrial
A7K99_20515	ENOG410643X	FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin
A7K99_20520	ENOG410643X	FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin
A7K99_20565	ENOG4105D7T	ABC transporter
A7K99_20570	ENOG4107QZF	nitrite reductase NADPH large subunit
A7K99_20575	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A7K99_20580	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A7K99_20585	ENOG4105E7U	AraC family transcriptional regulator
A7K99_20625	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A7K99_20630	ENOG4105D01	(LipO)protein
A7K99_20640	ENOG4105FBW	Monooxygenase
A7K99_20645	ENOG4105EAB	amino acid AbC transporter
A7K99_20650	ENOG4107T8P	acyl-Coa dehydrogenase
A7K99_20665	ENOG4108HW4	amino acid AbC transporter
A7K99_20675	ENOG4105CK2	sodium dicarboxylate symporter
A7K99_20685	ENOG4105GAV	receptor
A7K99_20690	ENOG4108S3W	Anti-feci sigma factor, fecr
A7K99_20695	ENOG4108SF5	RNA Polymerase
A7K99_20715	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A7K99_20720	ENOG4105DJB	Major Facilitator Superfamily
A7K99_20725	ENOG4105ETE	Transcriptional regulator (LacI family
A7K99_20740	ENOG4105G63	Type III effector Hrp-dependent
A7K99_20745	ENOG4108VMM	UPF0756 membrane protein
A7K99_20765	ENOG4107VIJ	nudix hydrolase
A7K99_20770	ENOG4105TW1	Carbohydrate-selective porin OprB
A7K99_20775	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A7K99_20785	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
A7K99_20790	ENOG4105D4P	Coproporphyrinogen iii oxidase
A7K99_20795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A7K99_20800	ENOG4105CUX	Signal transduction histidine kinase
A7K99_20805	ENOG4105C5F	glutamine synthetase
A7K99_20825	ENOG4105JQN	Transcriptional regulator
A7K99_20850	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
A7K99_20865	ENOG4105SUU	thioesterase domain
A7K99_20870	ENOG4105JV1	AsmA family
A7K99_20875	ENOG4105C2W	permease
A7K99_20880	ENOG4105CB5	ATP-dependent DNA helicase recG
A7K99_20885	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
A7K99_20890	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A7K99_20895	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A7K99_20900	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A7K99_20905	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
A7K99_20910	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
A7K99_20915	ENOG4105C8U	phosphate abc transporter
A7K99_20920	ENOG4105E2Z	phosphate ABC transporter (Permease
A7K99_20935	ENOG4107RGD	Major Facilitator superfamily
A7K99_20945	ENOG4108MBX	Secretion Protein
A7K99_20950	ENOG4108JJA	ABC, transporter
A7K99_20965	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A7K99_20970	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A7K99_20975	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)