locus-tag	class	description
TASI_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TASI_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TASI_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TASI_0004	ENOG4105C34	Pseudouridine synthase
TASI_0005	ENOG4108JQ7	(ABC) transporter
TASI_0006	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TASI_0007	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TASI_0008	ENOG4105C3U	ABC transporter
TASI_0011	ENOG4107QKA	exodeoxyribonuclease V beta
TASI_0012	ENOG4105DP0	ferredoxin-NADP reductase
TASI_0014	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TASI_0015	ENOG4105D4P	Coproporphyrinogen iii oxidase
TASI_0018	ENOG4108RPN	Protein smg homolog
TASI_0020	ENOG4108Z33	Thiol disulfide Interchange Protein
TASI_0022	ENOG4105C75	arginyL-tRNA synthetase
TASI_0024	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TASI_0027	ENOG4105W53	bacterioferritin-associated ferredoxin
TASI_0028	ENOG4108UQY	Iron-storage protein
TASI_0030	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
TASI_0034	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TASI_0035	ENOG4105KD1	integral membrane protein
TASI_0039	ENOG4105E89	ABC transporter
TASI_0040	ENOG4105DSP	amino acid AbC transporter
TASI_0041	ENOG4106YG3	ABC transporter
TASI_0042	ENOG4108JEH	abc transporter atp-binding protein
TASI_0043	ENOG4105HF0	Membrane
TASI_0046	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TASI_0048	ENOG4105C9M	aspartyl-trna synthetase
TASI_0050	ENOG4108Z4T	Peptidase M50
TASI_0051	ENOG4105D16	lipopolysaccharide heptosyltransferase i
TASI_0052	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
TASI_0054	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TASI_0057	ENOG4105DZ1	carboxypeptidase
TASI_0060	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TASI_0063	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TASI_0064	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TASI_0066	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TASI_0068	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TASI_0070	ENOG4105C1J	atp-dependent rna helicase
TASI_0071	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TASI_0072	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TASI_0074	ENOG4105ES5	Histidine kinase
TASI_0075	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TASI_0076	ENOG4105C1A	potassium transporter peripheral membrane
TASI_0077	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TASI_0078	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TASI_0079	ENOG4105MJ2	Competence protein
TASI_0080	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TASI_0082	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TASI_0087	ENOG4106VK6	Flagellar motor protein
TASI_0094	ENOG4108WC9	type VI secretion system effector, hcp1 family
TASI_0099	ENOG4105UGU	tonB-dependent Receptor
TASI_0138	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
TASI_0139	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TASI_0140	ENOG4105VW4	glutaredoxin 3
TASI_0141	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
TASI_0142	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TASI_0143	ENOG41063SB	peptidase
TASI_0144	ENOG4105CN1	protease
TASI_0145	ENOG4105D06	uba thif-type nad fad binding protein
TASI_0146	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
TASI_0149	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
TASI_0150	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TASI_0151	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TASI_0152	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TASI_0153	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TASI_0154	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TASI_0155	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TASI_0156	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TASI_0159	ENOG4105PE1	Receptor
TASI_0160	ENOG4105CJ1	ABC, transporter
TASI_0163	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TASI_0164	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
TASI_0165	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
TASI_0166	ENOG4105CKI	cobalamin synthesis protein
TASI_0167	ENOG4105MYN	Zinc uptake regulation protein
TASI_0169	ENOG4107T0D	ABC, transporter
TASI_0170	ENOG4105CC5	ABC transporter
TASI_0171	ENOG4108J6E	Pfam:Phage_integr_N
TASI_0173	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TASI_0174	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TASI_0175	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TASI_0176	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TASI_0177	ENOG4105DFF	Rod shape-determining protein mreb
TASI_0180	ENOG4105CJN	penicillin-binding protein
TASI_0181	ENOG4105CNI	cell division protein FtsW
TASI_0183	ENOG4105CAK	Cell division ATP-binding protein ftsE
TASI_0184	ENOG4105EZ7	amino acid ABC transporter
TASI_0185	ENOG4105DRP	amino acid AbC transporter
TASI_0186	ENOG4105CDA	abc transporter atp-binding protein
TASI_0189	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TASI_0194	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TASI_0195	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
TASI_0196	ENOG4105D7W	serine acetyltransferase
TASI_0197	ENOG4105M6F	mutator MutT protein
TASI_0199	ENOG4105EAH	synthase
TASI_0200	ENOG4105C01	Dihydroxy-acid dehydratase
TASI_0201	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TASI_0206	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TASI_0208	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TASI_0209	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
TASI_0210	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TASI_0211	ENOG4105C25	Primosomal protein n'
TASI_0213	ENOG4105E4P	ATPase (AAA
TASI_0214	ENOG4105CFP	Peptidase U32
TASI_0219	ENOG4107QSI	ABC, transporter
TASI_0220	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TASI_0221	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TASI_0222	ENOG4105C3U	ABC transporter
TASI_0223	ENOG4108JQ7	(ABC) transporter
TASI_0226	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TASI_0228	ENOG4105DJV	ribulose-phosphate 3-epimerase
TASI_0229	ENOG4105CA3	membrane-bound lytic murein transglycosylase
TASI_0230	ENOG4105T95	Thiol disulfide interChange protein
TASI_0231	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TASI_0232	ENOG4105W4M	Transport-associated protein
TASI_0233	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
TASI_0234	ENOG41082RQ	UPF0102 protein
TASI_0238	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TASI_0239	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
TASI_0240	ENOG4108IUZ	ABC transporter
TASI_0243	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
TASI_0244	ENOG4105C2X	Arabinose 5-phosphate isomerase
TASI_0245	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TASI_0246	ENOG4105C7B	Threonine dehydratase
TASI_0247	ENOG4105BZU	Histidine kinase
TASI_0248	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TASI_0249	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TASI_0251	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TASI_0252	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TASI_0253	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TASI_0254	ENOG4105DWF	phosphomethylpyrimidine kinase
TASI_0255	ENOG4105CSR	polyphosphate kinase 2
TASI_0256	ENOG4105DC8	reductase
TASI_0259	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TASI_0260	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TASI_0264	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TASI_0265	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TASI_0268	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TASI_0270	ENOG4107QPK	)-transporter
TASI_0271	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TASI_0280	ENOG4105C8Y	Acetylornithine aminotransferase
TASI_0282	ENOG4105HSA	Protein of unknown function (DUF452)
TASI_0283	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TASI_0284	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
TASI_0285	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
TASI_0286	ENOG4105CPQ	Dehydrogenase
TASI_0291	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
TASI_0292	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TASI_0294	ENOG4105C3M	thioredoxin reductase
TASI_0295	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TASI_0296	ENOG4106YG3	ABC transporter
TASI_0297	ENOG4105DSP	amino acid AbC transporter
TASI_0298	ENOG4105E89	ABC transporter
TASI_0300	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TASI_0301	ENOG4107YZX	Universal stress protein
TASI_0302	ENOG4108JDX	DNA polymerase iii, epsilon subunit
TASI_0303	ENOG4107RZZ	dna polymerase iii epsilon subunit
TASI_0304	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
TASI_0311	ENOG4105CRE	cytochrome C
TASI_0312	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TASI_0313	ENOG4109066	lysm domain bon superfamily protein
TASI_0314	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TASI_0317	ENOG4105D1F	ATP-binding protein
TASI_0320	ENOG4105DHP	deoxycytidine triphosphate deaminase
TASI_0321	ENOG4105CBX	hi0933 family
TASI_0323	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TASI_0324	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TASI_0325	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TASI_0326	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
TASI_0328	ENOG4107QQG	Dehydrogenase
TASI_0329	ENOG4107QKV	phosphomannomutase
TASI_0330	ENOG4105CQB	FAD linked oxidase domain protein
TASI_0331	ENOG4105EJG	cellulose synthase
TASI_0332	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
TASI_0333	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TASI_0335	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TASI_0336	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TASI_0339	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TASI_0341	ENOG4105C3G	gtp-binding protein
TASI_0342	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
TASI_0344	ENOG4106H78	methyltransferase
TASI_0349	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TASI_0350	ENOG4107YIM	Involved in the transcription termination process (By similarity)
TASI_0351	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TASI_0352	ENOG4108ZAI	phosphatidylglycerophosphatase a
TASI_0353	ENOG4107TH8	cina domain protein
TASI_0354	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
TASI_0355	ENOG41080IJ	Diacylglycerol kinase
TASI_0356	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TASI_0357	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TASI_0358	ENOG4107QXX	ABC transporter
TASI_0363	ENOG4105KCK	Peptidoglycan-associated lipoprotein
TASI_0364	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
TASI_0367	ENOG4105E02	MotA TolQ exbB proton channel
TASI_0368	ENOG4107YD3	Thioesterase
TASI_0369	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TASI_0370	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
TASI_0371	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TASI_0376	ENOG4105C26	Dehydrogenase
TASI_0377	ENOG4105CK7	Sodium proline symporter
TASI_0383	ENOG4105EUR	Domain-Containing protein
TASI_0384	ENOG4105C8J	)-transporter
TASI_0386	ENOG4105D3Q	Sugar transferase
TASI_0387	ENOG4107WZ3	Transferase
TASI_0388	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TASI_0391	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TASI_0394	ENOG4105EXC	Acyl-transferase
TASI_0396	ENOG4105E9K	Isocitrate dehydrogenase
TASI_0398	ENOG4105EKE	dihydroorotase
TASI_0401	ENOG4105DEF	Extracellular solute-binding protein, family 5
TASI_0402	ENOG4105DEF	Extracellular solute-binding protein, family 5
TASI_0403	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TASI_0404	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TASI_0405	ENOG4105C3U	ABC transporter
TASI_0406	ENOG4108JQ7	(ABC) transporter
TASI_0409	ENOG4105CP7	Triose-phosphate isomerase
TASI_0417	ENOG4108UUM	single-stranded DNA-binding protein
TASI_0439	ENOG41061CV	Terminase small subunit 
TASI_0469	ENOG4105W7J	DNA binding
TASI_0479	ENOG4108Z9W	Outer membrane porin
TASI_0480	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TASI_0481	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TASI_0482	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TASI_0483	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TASI_0484	ENOG4105GKE	subunit e
TASI_0487	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TASI_0488	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TASI_0489	ENOG4105DF2	NADH dehydrogenase subunit j
TASI_0490	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TASI_0492	ENOG4105C8S	subunit m
TASI_0493	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TASI_0497	ENOG4105EAC	phosphoserine phosphatase
TASI_0498	ENOG4108JA2	transcriptioN-repair coupling factor
TASI_0499	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TASI_0502	ENOG4105D3R	alkyl hydroperoxide reductase
TASI_0503	ENOG4105E0F	Histidine kinase
TASI_0504	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TASI_0505	ENOG41072GX	Peptidase M22 Glycoprotease
TASI_0510	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TASI_0511	ENOG4107TF3	peptidylprolyl cis-trans isomerase
TASI_0513	ENOG4107835	probably involved in intracellular septation (By similarity)
TASI_0518	ENOG4105C0Z	ABC transporter
TASI_0519	ENOG4108IV0	ABC, transporter
TASI_0521	ENOG4105CSM	endonuclease III
TASI_0523	ENOG4105DP0	ferredoxin-NADP reductase
TASI_0524	ENOG4108Z4U	Ferredoxin
TASI_0525	ENOG4107RH7	Nicotinate phosphoribosyltransferase
TASI_0526	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TASI_0527	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TASI_0528	ENOG4105C03	ribonuclease
TASI_0529	ENOG4105EI2	Pseudouridine synthase
TASI_0530	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TASI_0531	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TASI_0532	ENOG4108UHJ	MAF-like protein
TASI_0534	ENOG4105VGS	50s ribosomal protein l32
TASI_0535	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
TASI_0536	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TASI_0537	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TASI_0538	ENOG4105CHR	reductase
TASI_0539	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TASI_0540	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TASI_0541	ENOG4105C0H	protease
TASI_0542	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TASI_0543	ENOG4105C3F	Signal peptidase i
TASI_0544	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TASI_0545	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TASI_0546	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
TASI_0547	ENOG4108MN8	Membrane
TASI_0549	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TASI_0552	ENOG4107R11	Transcriptional regulator
TASI_0553	ENOG4105W1N	transcriptional regulator
TASI_0556	ENOG4107TT5	NLP P60 protein
TASI_0557	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
TASI_0558	ENOG4105DC7	peptidase M24
TASI_0563	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TASI_0566	ENOG4105W0E	50S ribosomal protein L33
TASI_0567	ENOG4105KDC	50s ribosomal protein l28
TASI_0568	ENOG4107QI1	Mate efflux family protein
TASI_0570	ENOG4105NRA	50s ribosomal protein l31 type b
TASI_0571	ENOG4105W5Q	DNA repair protein (RadC
TASI_0572	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TASI_0574	ENOG4108Z03	MAF-like protein
TASI_0575	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
TASI_0576	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
TASI_0577	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TASI_0579	ENOG4105CDY	transcriptional regulatory protein
TASI_0580	ENOG4105D7A	ATP-binding protein
TASI_0581	ENOG4105MZU	cell filamentation protein
TASI_0582	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TASI_0583	ENOG4105CD8	aminopeptidase N
TASI_0584	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TASI_0585	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TASI_0586	ENOG4107QTF	adenylosuccinate lyase
TASI_0587	ENOG4105T86	cytochrome C
TASI_0591	ENOG4105CBC	glutamate synthase
TASI_0597	ENOG4105C5H	ABC transporter
TASI_0598	ENOG4105CVE	Lytic murein transglycosylase
TASI_0599	ENOG4105CN1	protease
TASI_0601	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TASI_0602	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TASI_0603	ENOG4105UYK	outer membrane protein a
TASI_0604	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TASI_0605	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
TASI_0606	ENOG4105CQC	Prephenate dehydratase
TASI_0607	ENOG4105EVN	Prephenate dehydrogenase
TASI_0608	ENOG4105CAT	Cytidine monophosphate kinase
TASI_0609	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TASI_0612	ENOG4105CFV	Tetratricopeptide repeat protein
TASI_0613	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TASI_0617	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
TASI_0623	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
TASI_0625	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TASI_0627	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TASI_0629	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TASI_0630	ENOG4108YXA	Membrane
TASI_0633	ENOG4105C8T	Leucyl-tRNA synthetase
TASI_0634	ENOG4105CIN	aminoacyl-histidine dipeptidase
TASI_0635	ENOG4105EZE	Cupin 4 family protein
TASI_0636	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TASI_0637	ENOG4105D64	Mechanosensitive ion channel
TASI_0638	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
TASI_0639	ENOG4105ECY	inositol monophosphatase
TASI_0640	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TASI_0644	ENOG4105C8N	cysteinyl-tRNA synthetase
TASI_0645	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TASI_0646	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TASI_0653	ENOG4105CFH	Aspartokinase
TASI_0655	ENOG4108VPT	UPF0234 protein
TASI_0656	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TASI_0658	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TASI_0659	ENOG4107QIJ	Aconitate hydratase 2
TASI_0662	ENOG4105C31	Tryptophanyl-tRNA synthetase
TASI_0663	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
TASI_0666	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TASI_0667	ENOG4105K63	Thioredoxin
TASI_0668	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TASI_0669	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TASI_0670	ENOG4108EX3	reductase
TASI_0672	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TASI_0673	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
TASI_0674	ENOG4105K5M	30s ribosomal protein S16
TASI_0675	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TASI_0676	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TASI_0677	ENOG4105KJF	protein tyrosine phosphatase
TASI_0678	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
TASI_0679	ENOG4105C3J	Cysteine desulfurase
TASI_0680	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
TASI_0681	ENOG4108Z4V	iron-sulfur cluster assembly
TASI_0682	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
TASI_0683	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
TASI_0684	ENOG4108ZIT	Ferredoxin, 2FE-2S
TASI_0689	ENOG4105CRK	lysyL-tRNA synthetase
TASI_0690	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TASI_0691	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TASI_0693	ENOG4105D60	lipoprotein releasing system transmembrane protein
TASI_0694	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TASI_0695	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
TASI_0696	ENOG4105F8V	Hydrolase, tatD family
TASI_0697	ENOG4108EC8	DNA internalization-related competence protein ComEC
TASI_0698	ENOG4105DB7	PHP domain protein
TASI_0699	ENOG4108RRZ	Transcription elongation factor GreB
TASI_0700	ENOG4105D6S	protein involved in catabolism of external DNA
TASI_0701	ENOG4107TF3	peptidylprolyl cis-trans isomerase
TASI_0702	ENOG4105VJV	50s ribosomal protein L35
TASI_0703	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TASI_0704	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TASI_0706	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TASI_0708	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TASI_0709	ENOG4105DMF	Dehydrogenase
TASI_0710	ENOG4105C6T	cysteine synthase
TASI_0712	ENOG41088T4	Helicase IV
TASI_0716	ENOG41061WM	D-Alanyl-D-Alanine
TASI_0717	ENOG4108ETH	Formylglycinamide ribotide synthetase
TASI_0718	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TASI_0720	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TASI_0723	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TASI_0724	ENOG41063SR	receptor
TASI_0725	ENOG4105RV9	Transcriptional regulator
TASI_0726	ENOG4105EUB	pirin domain protein
TASI_0729	ENOG4108Z6B	deaminase
TASI_0730	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
TASI_0731	ENOG4105C5H	ABC transporter
TASI_0733	ENOG4105C7N	Xanthine uracil vitamin C permease
TASI_0735	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TASI_0737	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TASI_0738	ENOG4108K5P	(LipO)protein
TASI_0740	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TASI_0742	ENOG4105CHR	reductase
TASI_0743	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TASI_0745	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TASI_0746	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TASI_0747	ENOG4108ZCF	integral membrane protein
TASI_0748	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TASI_0752	ENOG4105F0N	pyrophosphate phospho-hydrolase
TASI_0755	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TASI_0756	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TASI_0757	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TASI_0759	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TASI_0760	ENOG4105CUT	histidyl-tRNA synthetase
TASI_0761	ENOG4105N21	Membrane
TASI_0762	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TASI_0763	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TASI_0764	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TASI_0765	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TASI_0766	ENOG4107QJR	hflk protein
TASI_0767	ENOG4105EPW	hflc protein
TASI_0768	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TASI_0770	ENOG4105VCC	30S ribosomal protein S21
TASI_0771	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TASI_0772	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TASI_0775	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
TASI_0788	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TASI_0789	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
TASI_0790	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
TASI_0791	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TASI_0792	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
TASI_0793	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TASI_0794	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TASI_0795	ENOG4105BZJ	Electron transfer flavoprotein
TASI_0796	ENOG4105C10	Electron transfer flavoprotein
TASI_0798	ENOG4105CUV	Homoserine Kinase
TASI_0800	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TASI_0801	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TASI_0802	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TASI_0803	ENOG4107S2Z	UPF0761 membrane protein
TASI_0805	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TASI_0806	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TASI_0807	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TASI_0808	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TASI_0809	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TASI_0813	ENOG4105C5H	ABC transporter
TASI_0814	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
TASI_0815	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TASI_0816	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
TASI_0817	ENOG4105CHR	reductase
TASI_0821	ENOG4105F4G	Membrane
TASI_0825	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TASI_0826	ENOG4105CGF	Aromatic amino acid aminotransferase
TASI_0827	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TASI_0830	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TASI_0831	ENOG4105Y3E	Modulates RecA activity (By similarity)
TASI_0832	ENOG4105M5K	heptosyltransferase
TASI_0833	ENOG4105CH7	arginosuccinase
TASI_0835	ENOG4105C4K	Nad synthetase
TASI_0836	ENOG4108YZA	Nitrogen regulatory protein pii
TASI_0837	ENOG4105FE9	pseudouridine synthase
TASI_0839	ENOG4105CGK	Exodeoxyribonuclease III
TASI_0843	ENOG4105QYV	Membrane
TASI_0845	ENOG4105BZS	acriflavin resistance protein
TASI_0846	ENOG4105BZS	acriflavin resistance protein
TASI_0848	ENOG4105C26	Dehydrogenase
TASI_0852	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
TASI_0854	ENOG4105D65	subunit l
TASI_0855	ENOG4108ZE9	Monovalent cation H antiporter subunit C
TASI_0856	ENOG4107R4Z	monovalent cation h antiporter subunit d
TASI_0858	ENOG4105W4C	monovalent cation H antiporter subunit F
TASI_0859	ENOG4105KJM	monovalent cation h antiporter subunit g
TASI_0861	ENOG4105F8V	Hydrolase, tatD family
TASI_0862	ENOG4105FA2	dna polymerase iii
TASI_0863	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TASI_0864	ENOG4105HHA	aminodeoxychorismate lyase
TASI_0865	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
TASI_0867	ENOG4108Z1B	Cyclase dehydrase
TASI_0868	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TASI_0871	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TASI_0872	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TASI_0873	ENOG4108RWN	rrna methyltransferase
TASI_0875	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TASI_0876	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TASI_0877	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TASI_0878	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TASI_0879	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TASI_0880	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
TASI_0881	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TASI_0882	ENOG4105DZP	Membrane-associated zinc metalloprotease
TASI_0883	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TASI_0884	ENOG4105KNE	Phosphatidate cytidylyltransferase
TASI_0885	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TASI_0886	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TASI_0887	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TASI_0888	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TASI_0889	ENOG4105CE9	30S ribosomal protein S2
TASI_0891	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TASI_0892	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
TASI_0896	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TASI_0899	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TASI_0900	ENOG4108VKM	cytochrome b561
TASI_0901	ENOG4107QN2	dihydrolipoyl dehydrogenase
TASI_0902	ENOG4107QSN	dihydrolipoamide acetyltransferase
TASI_0903	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TASI_0904	ENOG4105BZU	Histidine kinase
TASI_0906	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TASI_0907	ENOG4105DGW	oligopeptidase A
TASI_0909	ENOG4108IV0	ABC, transporter
TASI_0910	ENOG4105C0Z	ABC transporter
TASI_0911	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TASI_0912	ENOG4105C32	Amino acid ABC transporter (Permease)
TASI_0913	ENOG4105II7	pyrroline-5-carboxylate reductase
TASI_0914	ENOG4105CP9	extracellular ligand-binding receptor
TASI_0915	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TASI_0916	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TASI_0917	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
TASI_0918	ENOG4105W49	UPF0434 protein
TASI_0919	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
TASI_0920	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TASI_0921	ENOG4105CJR	Integral membrane protein (MviN
TASI_0922	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
TASI_0924	ENOG4105DBV	ornithine carbamoyltransferase
TASI_0925	ENOG4105CDH	Citrulline--aspartate ligase
TASI_0928	ENOG4105CMI	transporter
TASI_0929	ENOG4105CJ1	ABC, transporter
TASI_0931	ENOG4105K70	DNA-binding protein
TASI_0932	ENOG4105C28	cystathionine
TASI_0933	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TASI_0934	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TASI_0935	ENOG4105EJ9	Membrane
TASI_0937	ENOG41082BV	acetyltransferase
TASI_0940	ENOG4105ED9	Protein of unknown function (DUF455)
TASI_0943	ENOG4108PAU	MotA TolQ exbB proton channel
TASI_0946	ENOG4105KK6	nuclease
TASI_0953	ENOG4105EUJ	GTP cyclohydrolase i
TASI_0954	ENOG4105C03	ribonuclease
TASI_0955	ENOG4105BZ1	(ABC) transporter
TASI_0957	ENOG4105C0B	DNA polymerase III (alpha subunit)
TASI_0958	ENOG4105CQ7	ATP-dependent helicase
TASI_0959	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
TASI_0960	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TASI_0961	ENOG4105E66	phosphoriboisomerase A
TASI_0962	ENOG4105D38	putrescine abc transporter
TASI_0963	ENOG4105F38	ABC transporter, permease
TASI_0964	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TASI_0965	ENOG4107RUE	extracellular solute-binding protein family 1
TASI_0966	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TASI_0967	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TASI_0970	ENOG4105D6E	homoserine dehydrogenase
TASI_0972	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TASI_0973	ENOG4108IAB	Phoh family
TASI_0974	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TASI_0975	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TASI_0976	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TASI_0978	ENOG4105D01	(LipO)protein
TASI_0980	ENOG4105D6Z	AFG1 family ATPase
TASI_0981	ENOG4107QN2	dihydrolipoyl dehydrogenase
TASI_0982	ENOG4105C7S	Dehydrogenase
TASI_0983	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TASI_0984	ENOG4105C6K	Malic enzyme
TASI_0986	ENOG4105D6U	Sodium Glutamate Symporter
TASI_0989	ENOG4105IKQ	hydratase
TASI_0991	ENOG4105D2S	major facilitator superfamily
TASI_0993	ENOG4105CFC	Transporter
TASI_0994	ENOG4108IA2	Sodium pantothenate symporter
TASI_1009	ENOG4105CKI	cobalamin synthesis protein
TASI_1012	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TASI_1014	ENOG4105DRS	transport system, permease
TASI_1015	ENOG4107QKW	extracellular solute-binding protein family 1
TASI_1018	ENOG4105BZN	citrate synthase
TASI_1019	ENOG41060IS	Flavinator of succinate dehydrogenase
TASI_1020	ENOG4105E33	succinate dehydrogenase
TASI_1023	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
TASI_1024	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TASI_1026	ENOG4105C26	Dehydrogenase
TASI_1035	ENOG4105CNA	YD repeat protein
TASI_1037	ENOG4105CS6	Rhs element vgr protein
TASI_1040	ENOG4105CS6	Rhs element vgr protein
TASI_1042	ENOG4105CS6	Rhs element vgr protein
TASI_1045	ENOG4105W0Z	cytoplasmic protein
TASI_1049	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TASI_1050	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TASI_1052	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TASI_1055	ENOG4105CJP	fad dependent oxidoreductase
TASI_1056	ENOG4105DFD	Na H antiporter
TASI_1057	ENOG4105C26	Dehydrogenase
TASI_1058	ENOG4105CIF	Ornithine Cyclodeaminase
TASI_1059	ENOG4105CK2	sodium dicarboxylate symporter
TASI_1060	ENOG4108JPW	Aminotransferase
TASI_1061	ENOG4105E32	cytoplasmic protein
TASI_1068	ENOG4105Z2P	Protein of unknown function (DUF465)
TASI_1070	ENOG4108WHG	pyridoxamine 5'-phosphate
TASI_1074	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TASI_1075	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TASI_1076	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TASI_1077	ENOG4105CHV	Transcription elongation factor NusA
TASI_1078	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
TASI_1079	ENOG4105FE9	pseudouridine synthase
TASI_1080	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TASI_1082	ENOG4105C34	Pseudouridine synthase
TASI_1083	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TASI_1084	ENOG4105DVT	helicase
TASI_1085	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TASI_1087	ENOG4105C4R	Atp-dependent dna helicase
TASI_1089	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TASI_1090	ENOG4105DTN	riboflavin biosynthesis protein ribF
TASI_1091	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TASI_1093	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TASI_1094	ENOG4108K81	inner membrane protein YghB
TASI_1095	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TASI_1097	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TASI_1098	ENOG4105VEQ	Cold shock protein
TASI_1100	ENOG4105C5Q	Transcriptional regulator
TASI_1101	ENOG4105CB5	ATP-dependent DNA helicase recG
TASI_1102	ENOG4105KME	endoribonuclease L-psp
TASI_1104	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
TASI_1105	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TASI_1108	ENOG4105C5F	glutamine synthetase
TASI_1109	ENOG4105CSA	Coproporphyrinogen iii oxidase
TASI_1110	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TASI_1111	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TASI_1112	ENOG4105DSJ	YicC domain protein
TASI_1113	ENOG4105CDU	Replicative dna helicase
TASI_1114	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TASI_1115	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TASI_1117	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TASI_1118	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TASI_1119	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TASI_1120	ENOG4105CTB	Polyprenyl synthetase
TASI_1121	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TASI_1123	ENOG4105C84	Histidine ammonia-lyase
TASI_1124	ENOG4105CZE	histidine utilization repressor
TASI_1125	ENOG4105KHC	sulfurtransferase
TASI_1127	ENOG4105D0M	Protease HtpX homolog
TASI_1128	ENOG4105C2M	dna polymerase I
TASI_1129	ENOG4108URH	decarboxylase
TASI_1130	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TASI_1132	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TASI_1133	ENOG41080Z8	PHOSPHOCARRIER protein
TASI_1135	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TASI_1136	ENOG4105C22	threonyL-tRNA synthetase
TASI_1138	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TASI_1139	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TASI_1140	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TASI_1141	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TASI_1144	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
TASI_1145	ENOG4105WPN	DNA integration recombination invertion protein
TASI_1150	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TASI_1151	ENOG4105GJM	(LipO)protein
TASI_1157	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TASI_1159	ENOG4105E6M	Sulphatase-modifying factor protein
TASI_1163	ENOG4105D82	Glutamate dehydrogenase
TASI_1164	ENOG4105UGU	tonB-dependent Receptor
TASI_1166	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TASI_1167	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TASI_1169	ENOG4105BZG	amino acid carrier protein
TASI_1170	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TASI_1171	ENOG4108ZP8	Acetolactate synthase small subunit
TASI_1172	ENOG4105C7K	acetolactate synthase
TASI_1173	ENOG4105D1Q	UPF0246 protein
TASI_1174	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TASI_1175	ENOG4105D1H	recombination factor protein RarA
TASI_1176	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
TASI_1177	ENOG4105CNU	cell division protein FtsK
TASI_1178	ENOG4105C3M	thioredoxin reductase
TASI_1180	ENOG4108VMM	UPF0756 membrane protein
TASI_1182	ENOG4105HMI	Membrane
TASI_1189	ENOG4105CFG	Acts as a chaperone (By similarity)
TASI_1190	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TASI_1192	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TASI_1193	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TASI_1194	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TASI_1195	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TASI_1196	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TASI_1197	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TASI_1198	ENOG41090R7	Ferric uptake
TASI_1202	ENOG4105PGM	cation diffusion facilitator family transporter
TASI_1206	ENOG4105EZR	dyp-type peroxidase family protein
TASI_1208	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TASI_1209	ENOG4105E2Z	phosphate ABC transporter (Permease
TASI_1210	ENOG4105C8U	phosphate abc transporter
TASI_1211	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
TASI_1212	ENOG4105C9X	ppx gppa phosphatase
TASI_1214	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TASI_1216	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TASI_1217	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TASI_1218	ENOG4105HBR	Rna-binding protein
TASI_1219	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TASI_1220	ENOG4105C2W	permease
TASI_1221	ENOG4108UWD	Iron-storage protein
TASI_1222	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TASI_1223	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TASI_1224	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TASI_1227	ENOG4107QMP	dna polymerase iii subunits gamma and tau
TASI_1228	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
TASI_1232	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
TASI_1234	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TASI_1235	ENOG4105K8N	protein family UPF0079, ATPase
TASI_1236	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TASI_1237	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TASI_1239	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TASI_1240	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
TASI_1241	ENOG4105DJ0	Poly(A) Polymerase
TASI_1242	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TASI_1244	ENOG4107QP8	phosphohexose isomerase
TASI_1245	ENOG4105NQN	cytochrome C
TASI_1251	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TASI_1253	ENOG4105C1J	atp-dependent rna helicase
TASI_1255	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TASI_1257	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TASI_1258	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TASI_1259	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TASI_1261	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TASI_1262	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TASI_1263	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TASI_1266	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TASI_1271	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
TASI_1272	ENOG4105CJW	magnesium transporter
TASI_1273	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TASI_1274	ENOG4105DR5	peptidase
TASI_1276	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TASI_1277	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TASI_1278	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TASI_1279	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
TASI_1280	ENOG4105CPF	Cell wall formation (By similarity)
TASI_1281	ENOG4105DFU	Cell wall formation (By similarity)
TASI_1282	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TASI_1283	ENOG4105CNI	cell division protein FtsW
TASI_1284	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TASI_1285	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TASI_1286	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TASI_1287	ENOG4105CJN	penicillin-binding protein
TASI_1289	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TASI_1290	ENOG4108V6E	Cell division protein mraZ
TASI_1292	ENOG4105CH6	catalase
TASI_1293	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
TASI_1294	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
TASI_1295	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
TASI_1298	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TASI_1299	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
TASI_1300	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
TASI_1301	ENOG4105EHM	Aminoglycoside phosphotransferase
TASI_1302	ENOG4108S0S	Nucleotidyl transferase
TASI_1304	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TASI_1305	ENOG4105E0F	Histidine kinase
TASI_1306	ENOG4105CX6	glutaminyL-tRNA synthetase
TASI_1307	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TASI_1308	ENOG4107QMS	site-determining protein
TASI_1309	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TASI_1310	ENOG4105DZC	cytosine deaminase
TASI_1312	ENOG4105C5H	ABC transporter
TASI_1315	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
TASI_1316	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TASI_1317	ENOG4105CUZ	uba thif-type nad fad binding protein
TASI_1318	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
TASI_1319	ENOG4105CA0	peroxidase
TASI_1320	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TASI_1321	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TASI_1323	ENOG4105C8V	SAICAR synthetase
TASI_1325	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
TASI_1326	ENOG4105BZA	Phosphoglycerate kinase
TASI_1327	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TASI_1328	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TASI_1329	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TASI_1332	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TASI_1336	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TASI_1337	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TASI_1338	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TASI_1339	ENOG4105VIE	preprotein translocase, subunit YajC
TASI_1340	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TASI_1341	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TASI_1342	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TASI_1343	ENOG4105C9A	Phoh family
TASI_1344	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TASI_1345	ENOG4108JU5	Magnesium and cobalt efflux protein
TASI_1349	ENOG4105EUR	Domain-Containing protein
TASI_1350	ENOG4108JQ6	ABC transporter
TASI_1351	ENOG4105DEF	Extracellular solute-binding protein, family 5
TASI_1352	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TASI_1353	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TASI_1356	ENOG4105D44	asparaginase
TASI_1357	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TASI_1359	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TASI_1360	ENOG4105E9H	Lytic Murein transglycosylase
TASI_1363	ENOG4108R6K	riboflavin synthase, subunit alpha
TASI_1364	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TASI_1365	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TASI_1367	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TASI_1368	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TASI_1369	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
TASI_1370	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TASI_1372	ENOG4108UJD	30S ribosomal protein S9
TASI_1373	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TASI_1374	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
TASI_1376	ENOG4106CJB	Phospholipase Carboxylesterase
TASI_1377	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TASI_1383	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TASI_1384	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TASI_1385	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
TASI_1386	ENOG4105DFU	Cell wall formation (By similarity)
TASI_1388	ENOG4108K5H	permease YjgP YjgQ family protein
TASI_1389	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
TASI_1391	ENOG4105CD3	dihydroorotase
TASI_1392	ENOG4105CXT	aspartate transcarbamylase
TASI_1393	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TASI_1394	ENOG4108UJU	UPF0301 protein
TASI_1395	ENOG4105VCQ	rubredoxin
TASI_1396	ENOG4107U6I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TASI_1397	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TASI_1400	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TASI_1402	ENOG4105VCD	cytoplasmic protein
TASI_1403	ENOG4105D22	carbon starvation protein
TASI_1404	ENOG41079YP	Citrate utilization protein b
TASI_1405	ENOG4107EFR	Flavocytochrome c
TASI_1410	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TASI_1411	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TASI_1412	ENOG4105D1S	lipid A biosynthesis
TASI_1413	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TASI_1414	ENOG4105CGK	Exodeoxyribonuclease III
TASI_1416	ENOG4105EYM	Major Facilitator superfamily
TASI_1417	ENOG4105DWV	Homoserine O-trans-acetylase
TASI_1418	ENOG4105MPD	Cytochrome
TASI_1421	ENOG4105CXN	decarboxylase
TASI_1426	ENOG4108ZXC	Two component transcriptional regulator, luxr family
TASI_1427	ENOG4106AFQ	Histidine kinase
TASI_1429	ENOG4105NQN	cytochrome C
TASI_1437	ENOG4105KAF	membrAne
TASI_1439	ENOG4107MKT	Stringent starvation protein a
TASI_1440	ENOG4105EIX	cytochrome c1
TASI_1441	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TASI_1442	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TASI_1443	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TASI_1444	ENOG4107QNR	UPF0135 protein
TASI_1445	ENOG4105C0H	protease
TASI_1446	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TASI_1447	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
TASI_1448	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TASI_1449	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TASI_1450	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TASI_1452	ENOG4105E3A	(ABC) transporter
TASI_1453	ENOG4105DA5	(ABC) transporter
TASI_1456	ENOG4107PE3	Mammalian cell entry related domain protein
TASI_1457	ENOG4105CY3	ABC transporter, permease
TASI_1458	ENOG4105DHJ	ABC, transporter
TASI_1459	ENOG4105C79	DNA protecting protein DprA
TASI_1460	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TASI_1461	ENOG4105DFA	alanine racemase domain protein
TASI_1463	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TASI_1464	ENOG4105E0X	reductase
TASI_1465	ENOG4108UUM	single-stranded DNA-binding protein
TASI_1467	ENOG4107RDB	Major Facilitator
TASI_1471	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TASI_1472	ENOG4108JQC	penicillin-binding protein 1A
TASI_1473	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TASI_1475	ENOG4105XQ6	frataxin-like protein
TASI_1476	ENOG4105CRE	cytochrome C
TASI_1477	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
TASI_1479	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TASI_1480	ENOG4105D52	delta-aminolevulinic acid dehydratase
TASI_1481	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
TASI_1483	ENOG4105D6U	Sodium Glutamate Symporter
TASI_1484	ENOG41088SP	formiminoglutamate hydrolase
TASI_1485	ENOG4108ZT0	50S ribosomal protein l17
TASI_1486	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TASI_1487	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TASI_1488	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TASI_1489	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TASI_1492	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TASI_1493	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TASI_1494	ENOG4105VPB	50S ribosomal protein L30
TASI_1495	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TASI_1496	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TASI_1497	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TASI_1498	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TASI_1499	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TASI_1500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TASI_1501	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TASI_1502	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TASI_1503	ENOG4105D3Y	Na H antiporter
TASI_1504	ENOG4105D3Y	Na H antiporter
TASI_1505	ENOG4105CEI	nitrite reductase
TASI_1508	ENOG4105C59	p-type ATPase
TASI_1513	ENOG4108K3A	Glutathione S-transferase
TASI_1514	ENOG4105E4P	ATPase (AAA
TASI_1518	ENOG4105CB5	ATP-dependent DNA helicase recG
TASI_1522	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TASI_1523	ENOG41084PQ	50s ribosomal protein l29
TASI_1524	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TASI_1525	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TASI_1526	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TASI_1527	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TASI_1528	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TASI_1529	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TASI_1530	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TASI_1531	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TASI_1532	ENOG4105CGY	Dna recombination protein
TASI_1533	ENOG4105D01	(LipO)protein
TASI_1534	ENOG4108UMI	ABC transporter, permease
TASI_1535	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TASI_1536	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TASI_1537	ENOG4105BZ1	(ABC) transporter
TASI_1538	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TASI_1539	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TASI_1540	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TASI_1541	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TASI_1543	ENOG4105CI0	Citrate lyase
TASI_1545	ENOG4108M9J	MaoC like domain protein
TASI_1546	ENOG4105C1G	acyl-Coa dehydrogenase
TASI_1552	ENOG4107T6X	nag kinase
TASI_1554	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TASI_1558	ENOG4108JQ1	Dehydrogenase
TASI_1559	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TASI_1560	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TASI_1561	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TASI_1562	ENOG4108VZM	50s ribosomal protein L10
TASI_1563	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TASI_1564	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TASI_1565	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TASI_1566	ENOG4105PM1	preprotein translocase subunit SecE
TASI_1568	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TASI_1573	ENOG4105FA0	parb-like partition protein
TASI_1574	ENOG4107QJE	Chromosome Partitioning Protein
TASI_1575	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TASI_1576	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TASI_1577	ENOG4105K59	histidine triad (HIT) protein
TASI_1579	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TASI_1580	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TASI_1581	ENOG4105VG0	50S ribosomal protein l34