locus-tag	class	description
PG910_00005	COG0557	exoribonuclease II activity
PG910_00015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PG910_00020	COG0393	Putative heavy-metal-binding
PG910_00040	COG0445	tRNA wobble uridine modification
PG910_00045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PG910_00055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PG910_00055	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PG910_00070	COG0420	3'-5' exonuclease activity
PG910_00075	COG0419	ATPase involved in DNA repair
PG910_00080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PG910_00095	COG0758	DNA mediated transformation
PG910_00095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PG910_00115	COG0189	ligase activity
PG910_00115	COG4067	protein conserved in archaea
PG910_00120	COG0746	molybdenum cofactor guanylyltransferase activity
PG910_00125	COG0315	cyclic pyranopterin monophosphate synthase activity
PG910_00130	COG0303	'Molybdopterin
PG910_00135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PG910_00145	COG0322	excinuclease ABC activity
PG910_00150	COG1752	Esterase of the alpha-beta hydrolase superfamily
PG910_00155	COG1530	ribonuclease E activity
PG910_00160	COG0776	regulation of translation
PG910_00180	COG1629	transport
PG910_00180	COG4206	TonB-dependent receptor
PG910_00190	COG0629	single-stranded DNA binding
PG910_00220	COG0612	Peptidase, M16
PG910_00225	COG0612	Peptidase, M16
PG910_00235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PG910_00240	COG3279	Response regulator of the LytR AlgR family
PG910_00245	COG0745	RESPONSE REGULATOR receiver
PG910_00245	COG2972	Histidine kinase
PG910_00255	COG0826	peptidase U32
PG910_00260	COG1054	Belongs to the UPF0176 family
PG910_00265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PG910_00270	COG1418	mRNA catabolic process
PG910_00275	COG1024	Enoyl-CoA hydratase
PG910_00280	COG5000	phosphorelay sensor kinase activity
PG910_00285	COG0470	DNA polymerase III
PG910_00315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PG910_00330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PG910_00345	COG0489	protein tyrosine kinase activity
PG910_00355	COG0492	ferredoxin-NADP+ reductase activity
PG910_00365	COG0633	Ferredoxin
PG910_00370	COG2116	formate transmembrane transporter activity
PG910_00375	COG0716	FMN binding
PG910_00405	COG1607	acyl-coa hydrolase
PG910_00430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PG910_00435	COG4172	Belongs to the ABC transporter superfamily
PG910_00450	COG0488	(ABC) transporter
PG910_00465	COG0745	RESPONSE REGULATOR receiver
PG910_00470	COG5002	protein histidine kinase activity
PG910_00485	COG0793	Belongs to the peptidase S41A family
PG910_00490	COG0594	ribonuclease P activity
PG910_00500	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PG910_00515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PG910_00525	COG0193	aminoacyl-tRNA hydrolase activity
PG910_00540	COG0720	synthase
PG910_00550	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PG910_00555	COG0534	Mate efflux family protein
PG910_00560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PG910_00570	COG4585	Histidine kinase
PG910_00580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PG910_00585	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PG910_00595	COG3483	tryptophan 2,3-dioxygenase activity
PG910_00605	COG0739	heme binding
PG910_00610	COG0166	Belongs to the GPI family
PG910_00615	COG4771	TonB-dependent receptor
PG910_00655	COG0314	molybdopterin synthase activity
PG910_00660	COG0126	phosphoglycerate kinase activity
PG910_00685	COG2885	chlorophyll binding
PG910_00695	COG0180	Tryptophanyl-tRNA synthetase
PG910_00705	COG1272	protein, Hemolysin III
PG910_00710	COG2954	triphosphatase activity
PG910_00760	COG0840	transmembrane signaling receptor activity
PG910_00780	COG0632	four-way junction helicase activity
PG910_00795	COG0509	glycine decarboxylation via glycine cleavage system
PG910_00815	COG0463	Glycosyl transferase, family 2
PG910_00820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PG910_00845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PG910_00860	COG0515	serine threonine protein kinase
PG910_00860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PG910_00880	COG4771	TonB-dependent receptor
PG910_00895	COG0495	leucyl-tRNA aminoacylation
PG910_00915	COG1946	Acyl-CoA thioesterase
PG910_00920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PG910_00920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PG910_00930	COG1970	mechanosensitive ion channel activity
PG910_00935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PG910_00940	COG1435	thymidine kinase activity
PG910_00960	COG0779	Required for maturation of 30S ribosomal subunits
PG910_00965	COG0195	Participates in both transcription termination and antitermination
PG910_00970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PG910_01125	COG4771	TonB-dependent receptor
PG910_01135	COG0803	Belongs to the bacterial solute-binding protein 9 family
PG910_01140	COG1121	(ABC) transporter
PG910_01145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PG910_01150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PG910_01155	COG1074	ATP-dependent DNA helicase activity
PG910_01160	COG0156	8-amino-7-oxononanoate synthase activity
PG910_01170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PG910_01180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PG910_01185	COG4122	O-methyltransferase activity
PG910_01190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PG910_01195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PG910_01205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PG910_01215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PG910_01220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PG910_01250	COG0508	dehydrogenase complex catalyzes the overall conversion of
PG910_01255	COG1012	belongs to the aldehyde dehydrogenase family
PG910_01260	COG0564	pseudouridine synthase activity
PG910_01265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PG910_01270	COG2267	carboxylic ester hydrolase activity
PG910_01275	COG2001	Belongs to the MraZ family
PG910_01280	COG0275	rRNA processing
PG910_01290	COG0768	penicillin binding
PG910_01295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PG910_01300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PG910_01305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PG910_01310	COG0772	Belongs to the SEDS family
PG910_01315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PG910_01320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PG910_01335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PG910_01340	COG1610	YqeY-like protein
PG910_01355	COG0517	IMP dehydrogenase activity
PG910_01360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PG910_01365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PG910_01370	COG1595	DNA-templated transcription, initiation
PG910_01400	COG2226	methyltransferase
PG910_01405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PG910_01420	COG0442	prolyl-tRNA aminoacylation
PG910_01435	COG0268	Binds directly to 16S ribosomal RNA
PG910_01450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PG910_01455	COG1968	undecaprenyl-diphosphatase activity
PG910_01465	COG2177	Part of the ABC transporter FtsEX involved in
PG910_01470	COG0346	lactoylglutathione lyase activity
PG910_01475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PG910_01485	COG4591	ABC-type transport system involved in lipoprotein release permease component
PG910_01495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PG910_01515	COG0431	NADPH-dependent FMN reductase
PG910_01525	COG0481	GTPase activity
PG910_01540	COG4771	TonB-dependent receptor
PG910_01555	COG0252	asparaginase activity
PG910_01560	COG0811	peptide transport
PG910_01570	COG0848	biopolymer transport protein
PG910_01590	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PG910_01595	COG0017	Asparaginyl-tRNA synthetase
PG910_01610	COG0233	cytoplasmic translational termination
PG910_01615	COG0528	UMP kinase activity
PG910_01620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PG910_01625	COG0052	Belongs to the universal ribosomal protein uS2 family
PG910_01630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PG910_01635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PG910_01645	COG1477	protein flavinylation
PG910_01650	COG2226	methyltransferase
PG910_01660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PG910_01670	COG3186	Phenylalanine-4-hydroxylase
PG910_01720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PG910_01730	COG0702	epimerase
PG910_01750	COG0386	Belongs to the glutathione peroxidase family
PG910_01760	COG0415	Belongs to the DNA photolyase family
PG910_01765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PG910_01780	COG1629	transport
PG910_01780	COG4206	TonB-dependent receptor
PG910_01825	COG2363	Small membrane protein
PG910_01835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PG910_01845	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PG910_01860	COG1160	GTP binding
PG910_01905	COG2423	ornithine cyclodeaminase activity
PG910_01920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PG910_01925	COG0006	proline dipeptidase activity
PG910_01930	COG0006	proline dipeptidase activity
PG910_01935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PG910_01945	COG3938	Belongs to the proline racemase family
PG910_01955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PG910_01965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PG910_01985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PG910_01995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PG910_02005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PG910_02010	COG0596	Alpha beta hydrolase
PG910_02015	COG1950	PFAM Membrane protein of
PG910_02020	COG0544	peptidyl-prolyl cis-trans isomerase activity
PG910_02030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PG910_02040	COG0358	DNA primase activity
PG910_02045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PG910_02060	COG1428	Deoxynucleoside kinase
PG910_02070	COG1185	polyribonucleotide nucleotidyltransferase activity
PG910_02075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PG910_02080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PG910_02085	COG0191	fructose-bisphosphate aldolase activity
PG910_02095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PG910_02100	COG1428	Deoxynucleoside kinase
PG910_02110	COG0321	lipoyl(octanoyl) transferase activity
PG910_02120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PG910_02140	COG1490	D-aminoacyl-tRNA deacylase activity
PG910_02145	COG1162	GTPase activity
PG910_02150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PG910_02220	COG0857	belongs to the CobB CobQ family
PG910_02220	COG0280	phosphate acetyltransferase
PG910_02225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PG910_02230	COG0101	tRNA pseudouridine synthase activity
PG910_02235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PG910_02245	COG0463	Glycosyl transferase, family 2
PG910_02250	COG1960	acyl-CoA dehydrogenase activity
PG910_02265	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PG910_02270	COG0811	peptide transport
PG910_02275	COG0848	biopolymer transport protein
PG910_02285	COG0285	dihydrofolate synthase activity
PG910_02320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PG910_02350	COG2244	polysaccharide biosynthetic process
PG910_02380	COG1215	transferase activity, transferring glycosyl groups
PG910_02400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PG910_02410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PG910_02410	COG0519	Catalyzes the synthesis of GMP from XMP
PG910_02420	COG0295	cytidine deaminase activity
PG910_02430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PG910_02435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PG910_02445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PG910_02445	COG1333	cytochrome c biogenesis protein
PG910_02450	COG0688	phosphatidylethanolamine metabolic process
PG910_02460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG910_02460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG910_02465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG910_02505	COG4716	Myosin-crossreactive antigen
PG910_02520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PG910_02535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PG910_02540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PG910_02550	COG1132	(ABC) transporter
PG910_02555	COG0101	tRNA pseudouridine synthase activity
PG910_02565	COG4585	Histidine kinase
PG910_02575	COG2197	response regulator
PG910_02590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PG910_02595	COG2315	Protein conserved in bacteria
PG910_02605	COG0492	ferredoxin-NADP+ reductase activity
PG910_02615	COG0583	DNA-binding transcription factor activity
PG910_02620	COG1280	lysine exporter protein (LysE YggA)
PG910_02625	COG2866	Carboxypeptidase
PG910_02640	COG3579	cysteine-type endopeptidase activity
PG910_02660	COG1215	transferase activity, transferring glycosyl groups
PG910_02695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PG910_02700	COG0105	UTP biosynthetic process
PG910_02710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PG910_02755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PG910_02820	COG1678	Uncharacterized ACR, COG1678
PG910_02825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PG910_02845	COG4771	TonB-dependent receptor
PG910_02860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PG910_02865	COG1595	DNA-templated transcription, initiation
PG910_02875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PG910_02880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PG910_02895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PG910_02905	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PG910_02910	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PG910_02925	COG0681	Belongs to the peptidase S26 family
PG910_02930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PG910_02940	COG0592	DNA-directed DNA polymerase activity
PG910_02970	COG1104	cysteine desulfurase activity
PG910_02985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PG910_02990	COG1663	tetraacyldisaccharide 4'-kinase activity
PG910_02995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG910_03000	COG1136	(ABC) transporter
PG910_03010	COG0045	succinate-CoA ligase (ADP-forming) activity
PG910_03040	COG0556	nucleotide-excision repair
PG910_03060	COG1278	Cold shock
PG910_03065	COG1278	Cold shock
PG910_03070	COG1278	Cold shock
PG910_03095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PG910_03105	COG2329	Antibiotic biosynthesis monooxygenase
PG910_03110	COG4166	transmembrane transport
PG910_03130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PG910_03140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PG910_03150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PG910_03165	COG0300	oxidoreductase activity
PG910_03170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PG910_03175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PG910_03180	COG2996	Protein conserved in bacteria
PG910_03205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PG910_03210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PG910_03220	COG0552	protein localization to endoplasmic reticulum
PG910_03235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PG910_03250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PG910_03270	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
PG910_03275	COG1702	phosphate starvation-inducible protein PhoH
PG910_03285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PG910_03295	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PG910_03350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PG910_03360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PG910_03365	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PG910_03375	COG1482	cell wall glycoprotein biosynthetic process
PG910_03385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PG910_03415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PG910_03415	COG0321	lipoyl(octanoyl) transferase activity
PG910_03420	COG3022	response to hydroperoxide
PG910_03425	COG2949	membrane
PG910_03435	COG1760	l-serine dehydratase
PG910_03455	COG0205	6-phosphofructokinase activity
PG910_03465	COG0251	oxidation-reduction process
PG910_03470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PG910_03475	COG0860	N-Acetylmuramoyl-L-alanine amidase
PG910_03485	COG2181	nitrate reductase activity
PG910_03485	COG0247	lactate metabolic process
PG910_03490	COG2181	nitrate reductase activity
PG910_03490	COG0247	lactate metabolic process
PG910_03495	COG1575	Belongs to the MenA family. Type 1 subfamily
PG910_03500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PG910_03510	COG4948	Mandelate Racemase Muconate Lactonizing
PG910_03515	COG1266	CAAX protease self-immunity
PG910_03525	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PG910_03530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PG910_03535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PG910_03540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PG910_03545	COG1841	ribosomal large subunit assembly
PG910_03550	COG0200	Binds to the 23S rRNA
PG910_03555	COG0201	protein transport
PG910_03560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PG910_03565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PG910_03570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PG910_03575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PG910_03580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PG910_03585	COG0202	RNA polymerase activity
PG910_03590	COG0203	ribosomal protein L17
PG910_03595	COG0505	Belongs to the CarA family
PG910_03600	COG0148	phosphopyruvate hydratase activity
PG910_03610	COG0010	Belongs to the arginase family
PG910_03620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PG910_03635	COG0352	thiamine-phosphate diphosphorylase activity
PG910_03640	COG2022	thiamine diphosphate biosynthetic process
PG910_03645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PG910_03670	COG0300	oxidoreductase activity
PG910_03685	COG1120	ATPase activity
PG910_03690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PG910_03695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PG910_03705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PG910_03715	COG0339	signal peptide processing
PG910_03720	COG1295	ribonuclease BN
PG910_03725	COG0124	histidyl-tRNA synthetase
PG910_03730	COG0302	gtp cyclohydrolase
PG910_03735	COG1629	transport
PG910_03740	COG4771	TonB-dependent receptor
PG910_03785	COG1862	Preprotein translocase
PG910_03795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PG910_03805	COG1132	(ABC) transporter
PG910_03815	COG1169	isochorismate synthase
PG910_03820	COG2050	protein possibly involved in aromatic compounds catabolism
PG910_03830	COG0009	L-threonylcarbamoyladenylate synthase
PG910_03850	COG5290	Psort location Cytoplasmic, score
PG910_03855	COG0488	(ABC) transporter
PG910_03860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PG910_03885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PG910_03925	COG1418	mRNA catabolic process
PG910_03930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PG910_03950	COG0442	prolyl-tRNA aminoacylation
PG910_03970	COG0335	large ribosomal subunit rRNA binding
PG910_03975	COG0336	Belongs to the RNA methyltransferase TrmD family
PG910_03990	COG2195	Cleaves the N-terminal amino acid of tripeptides
PG910_03995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PG910_04005	COG1981	membrane
PG910_04015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PG910_04030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PG910_04040	COG0113	porphobilinogen synthase activity
PG910_04045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PG910_04050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PG910_04065	COG0408	coproporphyrinogen oxidase activity
PG910_04070	COG0508	dehydrogenase complex catalyzes the overall conversion of
PG910_04075	COG1090	epimerase
PG910_04090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG910_04090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG910_04100	COG0215	cysteine-tRNA ligase activity
PG910_04105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PG910_04110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PG910_04120	COG0590	tRNA wobble adenosine to inosine editing
PG910_04145	COG0706	membrane insertase activity
PG910_04150	COG0504	CTP synthase activity
PG910_04165	COG1607	acyl-coa hydrolase
PG910_04195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PG910_04200	COG1408	metallophosphoesterase
PG910_04240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PG910_04250	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PG910_04255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PG910_04265	COG4206	TonB-dependent receptor
PG910_04275	COG3011	Protein conserved in bacteria
PG910_04280	COG1136	(ABC) transporter
PG910_04285	COG0577	efflux transmembrane transporter activity
PG910_04285	COG1136	(ABC) transporter
PG910_04290	COG1136	(ABC) transporter
PG910_04290	COG0577	efflux transmembrane transporter activity
PG910_04305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PG910_04310	COG4628	conserved protein (DUF2132)
PG910_04315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PG910_04320	COG1028	Short-chain dehydrogenase reductase Sdr
PG910_04325	COG3956	TIGRFAM MazG family protein
PG910_04335	COG0242	peptide deformylase activity
PG910_04340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PG910_04350	COG0463	Glycosyl transferase, family 2
PG910_04375	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PG910_04375	COG0617	tRNA 3'-terminal CCA addition
PG910_04375	COG0517	IMP dehydrogenase activity
PG910_04380	COG1132	(ABC) transporter
PG910_04385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PG910_04390	COG0463	Glycosyl transferase, family 2
PG910_04405	COG4974	Belongs to the 'phage' integrase family
PG910_04415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PG910_04430	COG1183	phosphatidylcholine synthase activity
PG910_04435	COG1137	ATPase activity
PG910_04445	COG0805	protein transport
PG910_04450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PG910_04450	COG0517	IMP dehydrogenase activity
PG910_04455	COG0514	ATP-dependent DNA helicase (RecQ)
PG910_04465	COG0686	Belongs to the AlaDH PNT family
PG910_04470	COG0802	atpase or kinase
PG910_04475	COG2204	response regulator
PG910_04480	COG1078	dGTPase activity
PG910_04485	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG910_04490	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PG910_04490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PG910_04495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG910_04500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PG910_04510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PG910_04530	COG2096	Adenosyltransferase
PG910_04535	COG1797	cobyrinic acid a,c-diamide synthase activity
PG910_04540	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PG910_04550	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PG910_04570	COG0778	Nitroreductase
PG910_04590	COG1648	precorrin-2 dehydrogenase activity
PG910_04590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PG910_04620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PG910_04625	COG1492	cobalamin metabolic process
PG910_04630	COG1943	Transposase
PG910_04665	COG1690	Belongs to the RtcB family
PG910_04695	COG3002	Belongs to the UPF0753 family
PG910_04705	COG0659	secondary active sulfate transmembrane transporter activity
PG910_04780	COG4974	Belongs to the 'phage' integrase family
PG910_04785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PG910_04800	COG2373	Large extracellular alpha-helical protein
PG910_04815	COG0527	aspartate kinase activity
PG910_04815	COG0460	homoserine dehydrogenase
PG910_04825	COG1959	2 iron, 2 sulfur cluster binding
PG910_04835	COG0175	sulfate reduction
PG910_04840	COG0175	sulfate reduction
PG910_04850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PG910_04855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PG910_04855	COG1648	precorrin-2 dehydrogenase activity
PG910_04860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PG910_04860	COG1648	precorrin-2 dehydrogenase activity
PG910_04865	COG0492	ferredoxin-NADP+ reductase activity
PG910_04870	COG1045	serine acetyltransferase
PG910_04880	COG0646	methionine synthase
PG910_04880	COG1410	methionine synthase
PG910_04890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PG910_04900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PG910_04905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PG910_04910	COG0066	3-isopropylmalate dehydratase activity
PG910_04925	COG0129	dihydroxy-acid dehydratase activity
PG910_04930	COG0028	Belongs to the TPP enzyme family
PG910_04940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PG910_04945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PG910_04950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PG910_04960	COG0076	glutamate decarboxylase activity
PG910_04965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PG910_04975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PG910_04985	COG0360	Binds together with S18 to 16S ribosomal RNA
PG910_04990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PG910_04995	COG0359	binds to the 23S rRNA
PG910_05000	COG0019	diaminopimelate decarboxylase activity
PG910_05005	COG2195	Cleaves the N-terminal amino acid of tripeptides
PG910_05035	COG0438	transferase activity, transferring glycosyl groups
PG910_05040	COG1250	3-hydroxyacyl-CoA dehydrogenase
PG910_05055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PG910_05070	COG0813	purine-nucleoside phosphorylase activity
PG910_05110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PG910_05115	COG2885	chlorophyll binding
PG910_05125	COG0668	transmembrane transport
PG910_05130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PG910_05135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PG910_05135	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PG910_05160	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PG910_05200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PG910_05245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PG910_05250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PG910_05255	COG0484	heat shock protein binding
PG910_05275	COG1028	Short-chain dehydrogenase reductase Sdr
PG910_05305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PG910_05330	COG3958	Transketolase
PG910_05335	COG0424	maF-like protein
PG910_05345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PG910_05350	COG3047	cAMP biosynthetic process
PG910_05355	COG0542	response to heat
PG910_05375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PG910_05420	COG1979	alcohol dehydrogenase
PG910_05430	COG1309	transcriptional regulator
PG910_05435	COG1278	Cold shock
PG910_05440	COG1522	sequence-specific DNA binding
PG910_05445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PG910_05455	COG0564	pseudouridine synthase activity
PG910_05460	COG1522	sequence-specific DNA binding
PG910_05480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PG910_05485	COG0539	negative regulation of cytoplasmic translation
PG910_05500	COG1739	Uncharacterized protein family UPF0029
PG910_05505	COG0697	spore germination
PG910_05510	COG1011	Hydrolase
PG910_05515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PG910_05515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PG910_05525	COG2890	protein-(glutamine-N5) methyltransferase activity
PG910_05565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PG910_05580	COG0167	dihydroorotate dehydrogenase activity
PG910_05590	COG2356	endonuclease I
PG910_05610	COG1363	Peptidase, m42
PG910_05645	COG0488	(ABC) transporter
PG910_05695	COG1607	acyl-coa hydrolase
PG910_05725	COG4771	TonB-dependent receptor
PG910_05730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PG910_05775	COG1301	dicarboxylic acid transport
PG910_05790	COG0668	transmembrane transport
PG910_05815	COG3005	denitrification pathway
PG910_05820	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PG910_05825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PG910_05825	COG1333	cytochrome c biogenesis protein
PG910_05830	COG0517	IMP dehydrogenase activity
PG910_05830	COG0516	GMP reductase activity
PG910_05890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG910_05925	COG3842	ATPase activity
PG910_05930	COG1175	transmembrane transport
PG910_05950	COG1840	ABC-type Fe3 transport system, periplasmic component
PG910_05995	COG1595	DNA-templated transcription, initiation
PG910_06020	COG0525	valine-tRNA ligase activity
PG910_06035	COG0436	Aminotransferase
PG910_06040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PG910_06065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PG910_06085	COG3876	Protein conserved in bacteria
PG910_06120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PG910_06125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PG910_06135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PG910_06135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PG910_06165	COG0012	GTP binding
PG910_06180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PG910_06185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PG910_06205	COG1595	DNA-templated transcription, initiation
PG910_06210	COG3340	Belongs to the peptidase S51 family
PG910_06240	COG0714	Associated with various cellular activities
PG910_06265	COG0514	ATP-dependent DNA helicase (RecQ)
PG910_06270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PG910_06275	COG0776	regulation of translation
PG910_06280	COG2249	NAD(P)H dehydrogenase (quinone) activity
PG910_06285	COG0116	Belongs to the methyltransferase superfamily
PG910_06305	COG0602	queuosine metabolic process
PG910_06325	COG0343	queuine tRNA-ribosyltransferase activity
PG910_06330	COG1187	pseudouridine synthase activity
PG910_06360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PG910_06365	COG0564	pseudouridine synthase activity
PG910_06375	COG1181	Belongs to the D-alanine--D-alanine ligase family
PG910_06380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PG910_06385	COG1482	cell wall glycoprotein biosynthetic process
PG910_06400	COG0745	RESPONSE REGULATOR receiver
PG910_06445	COG3279	Response regulator of the LytR AlgR family
PG910_06455	COG4251	negative regulation of phosphorylation
PG910_06480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PG910_06485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PG910_06505	COG0243	molybdopterin cofactor binding
PG910_06520	COG0437	4 iron, 4 sulfur cluster binding
PG910_06540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PG910_06560	COG3012	SEC-C Motif Domain Protein
PG910_06565	COG0460	homoserine dehydrogenase
PG910_06565	COG0527	aspartate kinase activity
PG910_06570	COG0083	homoserine kinase activity
PG910_06575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PG910_06580	COG1022	Amp-dependent synthetase and ligase
PG910_06585	COG0564	pseudouridine synthase activity
PG910_06590	COG2270	Major facilitator Superfamily
PG910_06605	COG4771	TonB-dependent receptor
PG910_06610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PG910_06620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PG910_06625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PG910_06635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PG910_06645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PG910_06650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PG910_06670	COG0140	phosphoribosyl-ATP diphosphatase activity
PG910_06670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PG910_06675	COG0107	imidazoleglycerol-phosphate synthase activity
PG910_06680	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PG910_06690	COG0131	Imidazoleglycerol-phosphate dehydratase
PG910_06695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PG910_06700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PG910_06705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PG910_06715	COG1217	gtp-binding protein TYPA
PG910_06735	COG1228	amidohydrolase
PG910_06750	COG0010	Belongs to the arginase family
PG910_06780	COG3279	Response regulator of the LytR AlgR family
PG910_06785	COG2972	Histidine kinase
PG910_06805	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PG910_06810	COG1393	Belongs to the ArsC family
PG910_06830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PG910_06835	COG0497	DNA recombination
PG910_06865	COG1528	Iron-storage protein
PG910_06870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PG910_06890	COG4974	Belongs to the 'phage' integrase family
PG910_07000	COG3657	addiction module killer protein
PG910_07005	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PG910_07070	COG4680	protein conserved in bacteria
PG910_07090	COG3657	addiction module killer protein
PG910_07095	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PG910_07175	COG2304	oxidoreductase activity
PG910_07185	COG3586	endonuclease activity
PG910_07260	COG3586	endonuclease activity
PG910_07305	COG4680	protein conserved in bacteria
PG910_07395	COG0640	Transcriptional regulator
PG910_07400	COG5658	integral membrane protein
PG910_07640	COG4680	protein conserved in bacteria
PG910_07690	COG0280	phosphate acetyltransferase
PG910_07715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PG910_07725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PG910_07730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PG910_07740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PG910_07780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PG910_07785	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PG910_07790	COG0824	Thioesterase
PG910_07830	COG1620	l-lactate permease
PG910_07835	COG1304	FMN binding
PG910_07850	COG0534	Mate efflux family protein
PG910_07855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PG910_07865	COG1674	ftsk spoiiie
PG910_07880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PG910_07880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PG910_07890	COG0482	sulfurtransferase activity
PG910_07915	COG0018	arginyl-trna synthetase
PG910_07920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PG910_07980	COG0488	(ABC) transporter
PG910_07990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG910_07995	COG1902	pentaerythritol trinitrate reductase activity
PG910_07995	COG0446	pyridine nucleotide-disulphide oxidoreductase
PG910_08000	COG0076	glutamate decarboxylase activity
PG910_08005	COG1522	sequence-specific DNA binding
PG910_08045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PG910_08055	COG0217	transcriptional regulatory protein
PG910_08065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PG910_08070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PG910_08075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PG910_08080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PG910_08085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PG910_08090	COG0255	Belongs to the universal ribosomal protein uL29 family
PG910_08095	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PG910_08100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PG910_08105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PG910_08110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PG910_08115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PG910_08120	COG0089	rRNA binding
PG910_08125	COG0088	Forms part of the polypeptide exit tunnel
PG910_08130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PG910_08135	COG0051	transcription antitermination factor activity, RNA binding
PG910_08140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PG910_08145	COG0049	tRNA binding
PG910_08150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PG910_08155	COG1629	transport
PG910_08170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PG910_08180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PG910_08195	COG0569	domain protein
PG910_08245	COG1917	Cupin 2, conserved barrel domain protein
PG910_08260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PG910_08270	COG3844	kynureninase activity
PG910_08280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PG910_08290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PG910_08290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PG910_08295	COG0076	glutamate decarboxylase activity
PG910_08320	COG2813	Specifically methylates the guanine in position
PG910_08325	COG0069	glutamate synthase activity
PG910_08330	COG0254	rRNA binding
PG910_08375	COG2207	Transcriptional regulator
PG910_08375	COG1917	Cupin 2, conserved barrel domain protein
PG910_08385	COG1858	cytochrome C peroxidase
PG910_08395	COG1253	flavin adenine dinucleotide binding
PG910_08400	COG0783	Belongs to the Dps family
PG910_08410	COG0659	secondary active sulfate transmembrane transporter activity
PG910_08415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PG910_08420	COG0540	Belongs to the ATCase OTCase family
PG910_08435	COG1234	tRNA 3'-trailer cleavage
PG910_08450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PG910_08455	COG0326	Molecular chaperone. Has ATPase activity
PG910_08470	COG1629	transport
PG910_08470	COG4206	TonB-dependent receptor
PG910_08535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PG910_08595	COG0443	Heat shock 70 kDa protein
PG910_08600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PG910_08620	COG0799	negative regulation of ribosome biogenesis
PG910_08625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PG910_08635	COG4589	Belongs to the CDS family
PG910_08670	COG0277	FAD linked oxidase domain protein
PG910_08670	COG0247	lactate metabolic process
PG910_08685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PG910_08690	COG2373	Large extracellular alpha-helical protein
PG910_08700	COG1404	Belongs to the peptidase S8 family
PG910_08705	COG2234	aminopeptidase activity
PG910_08710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PG910_08725	COG3530	Putative quorum-sensing-regulated virulence factor
PG910_08775	COG0489	protein tyrosine kinase activity
PG910_08895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PG910_08930	COG2072	flavoprotein involved in K transport
PG910_08965	COG0589	response to stress
PG910_09020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PG910_09030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PG910_09035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PG910_09055	COG1842	Phage shock protein A
PG910_09065	COG1396	sequence-specific DNA binding
PG910_09075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PG910_09080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PG910_09090	COG2217	Heavy metal translocating P-type atpase
PG910_09115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PG910_09125	COG0222	ribosome binding
PG910_09130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PG910_09135	COG0081	regulation of translation
PG910_09190	COG4974	Belongs to the 'phage' integrase family
PG910_09195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PG910_09200	COG1960	acyl-CoA dehydrogenase activity
PG910_09210	COG1115	amino acid carrier protein
PG910_09265	COG1132	(ABC) transporter
PG910_09270	COG1611	Belongs to the LOG family
PG910_09290	COG0778	Nitroreductase
PG910_09295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PG910_09315	COG0450	alkyl hydroperoxide reductase
PG910_09325	COG3264	Mechanosensitive ion channel
PG910_09325	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PG910_09330	COG1668	transmembrane transport
PG910_09335	COG4152	abc transporter atp-binding protein
PG910_09340	COG1846	Transcriptional regulator
PG910_09345	COG1024	Enoyl-CoA hydratase
PG910_09345	COG1250	3-hydroxyacyl-CoA dehydrogenase
PG910_09350	COG0183	Belongs to the thiolase family
PG910_09355	COG1960	acyl-CoA dehydrogenase activity
PG910_09365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PG910_09375	COG0174	glutamine synthetase
PG910_09415	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PG910_09420	COG2264	protein methyltransferase activity
PG910_09425	COG0149	triose-phosphate isomerase activity
PG910_09435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG910_09445	COG0601	transmembrane transport
PG910_09450	COG0284	orotidine-5'-phosphate decarboxylase activity
PG910_09460	COG4771	TonB-dependent receptor
PG910_09465	COG3279	Response regulator of the LytR AlgR family
PG910_09485	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PG910_09490	COG2986	histidine ammonia-lyase
PG910_09495	COG0583	DNA-binding transcription factor activity
PG910_09505	COG1703	isobutyryl-CoA mutase activity
PG910_09505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG910_09505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG910_09520	COG0159	tryptophan synthase activity
PG910_09525	COG0133	tryptophan synthase activity
PG910_09530	COG0135	phosphoribosylanthranilate isomerase activity
PG910_09535	COG0134	indole-3-glycerol-phosphate synthase activity
PG910_09540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PG910_09545	COG0512	Glutamine amidotransferase of anthranilate synthase
PG910_09550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PG910_09555	COG0367	asparagine synthase
PG910_09560	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PG910_09565	COG0187	DNA topoisomerase II activity
PG910_09570	COG0039	L-malate dehydrogenase activity
PG910_09575	COG2884	Cell division ATP-binding protein ftsE
PG910_09595	COG0545	Peptidyl-prolyl cis-trans isomerase
PG910_09600	COG1595	DNA-templated transcription, initiation
PG910_09615	COG1127	ABC transporter
PG910_09620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PG910_09655	COG0183	Belongs to the thiolase family
PG910_09660	COG0791	NLP P60 protein
PG910_09675	COG0542	response to heat
PG910_09680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG910_09710	COG2733	membrane
PG910_09725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PG910_09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
PG910_09735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PG910_09765	COG1032	radical SAM domain protein
PG910_09790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PG910_09795	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PG910_09825	COG4191	Histidine kinase
PG910_09835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PG910_09845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PG910_09850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PG910_09855	COG0339	signal peptide processing
PG910_09935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PG910_09960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PG910_09965	COG3942	CHAP domain
PG910_09965	COG1705	Flagellar rod assembly protein muramidase FlgJ
PG910_09980	COG0488	(ABC) transporter
PG910_10010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PG910_10015	COG0010	Belongs to the arginase family
PG910_10025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PG910_10045	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PG910_10050	COG0459	protein refolding
PG910_10065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PG910_10090	COG2814	Major facilitator Superfamily
PG910_10100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PG910_10110	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PG910_10115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PG910_10120	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PG910_10125	COG2363	Small membrane protein
PG910_10155	COG1271	oxidase subunit
PG910_10160	COG1294	oxidase, subunit
PG910_10180	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PG910_10185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PG910_10185	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PG910_10190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PG910_10220	COG0519	Catalyzes the synthesis of GMP from XMP
PG910_10225	COG0616	signal peptide processing
PG910_10235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PG910_10295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PG910_10300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PG910_10315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
PG910_10320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PG910_10325	COG0563	adenylate kinase activity
PG910_10330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PG910_10335	COG0791	NLP P60 protein
PG910_10340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG910_10345	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PG910_10350	COG0793	Belongs to the peptidase S41A family
PG910_10375	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PG910_10380	COG2333	competence protein COMEC
PG910_10380	COG0658	competence protein
PG910_10400	COG1506	peptidase
PG910_10400	COG0823	Involved in the tonB-independent uptake of proteins
PG910_10415	COG2081	HI0933 family
PG910_10445	COG1629	transport
PG910_10485	COG1187	pseudouridine synthase activity
PG910_10510	COG0138	bifunctional purine biosynthesis protein purh
PG910_10515	COG1077	Cell shape determining protein MreB Mrl
PG910_10530	COG0768	penicillin binding
PG910_10535	COG0772	Belongs to the SEDS family
PG910_10555	COG1902	pentaerythritol trinitrate reductase activity
PG910_10560	COG2207	Transcriptional regulator
PG910_10615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PG910_10625	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PG910_10630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PG910_10635	COG0511	ligase activity, forming carbon-carbon bonds
PG910_10640	COG0439	Biotin carboxylase
PG910_10645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PG910_10645	COG1519	Transferase
PG910_10650	COG2391	methyltransferase activity
PG910_10665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PG910_10690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PG910_10705	COG3655	Transcriptional regulator
PG910_10715	COG1522	sequence-specific DNA binding
PG910_10730	COG3409	Peptidoglycan-binding domain 1 protein
PG910_10730	COG0793	Belongs to the peptidase S41A family
PG910_10745	COG4942	peptidase
PG910_10750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PG910_10755	COG0194	GDP metabolic process
PG910_10760	COG1561	YicC-like family, N-terminal region
PG910_10770	COG1652	LysM domain
PG910_10775	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PG910_10785	COG0316	Belongs to the HesB IscA family
PG910_10790	COG0719	Fe-S assembly protein
PG910_10795	COG0396	ATPase activity
PG910_10800	COG0719	Fe-S assembly protein
PG910_10805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PG910_10835	COG0668	transmembrane transport
PG910_10840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PG910_10850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PG910_10865	COG1757	Na H antiporter
PG910_10875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PG910_10885	COG2824	Alkylphosphonate utilization operon protein PhnA
PG910_10895	COG0228	four-way junction DNA binding
PG910_10900	COG1278	Cold shock
PG910_10930	COG0792	nuclease activity
PG910_10935	COG1619	proteins homologs of microcin C7 resistance protein MccF
PG910_10950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG910_10950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG910_10960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PG910_10965	COG0629	single-stranded DNA binding
PG910_10985	COG0469	pyruvate kinase activity
PG910_10995	COG0571	ribonuclease III activity
PG910_11005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PG910_11015	COG0328	RNA-DNA hybrid ribonuclease activity
PG910_11015	COG3341	Caulimovirus viroplasmin
PG910_11030	COG0668	transmembrane transport
PG910_11035	COG1214	PFAM Peptidase M22, glycoprotease
PG910_11055	COG2322	membrane
PG910_11060	COG1999	signal sequence binding
PG910_11075	COG1845	cytochrome c oxidase, subunit III
PG910_11080	COG1845	cytochrome c oxidase, subunit III
PG910_11085	COG0109	protoheme IX farnesyltransferase activity
PG910_11130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PG910_11135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PG910_11140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PG910_11150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PG910_11175	COG0508	dehydrogenase complex catalyzes the overall conversion of
PG910_11175	COG0022	dehydrogenase e1 component
PG910_11185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PG910_11205	COG0037	tRNA processing
PG910_11215	COG0606	chelatase, subunit chli
PG910_11220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG910_11225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG910_11235	COG1528	Iron-storage protein
PG910_11240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PG910_11265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PG910_11285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PG910_11290	COG0297	glycogen (starch) synthase activity
PG910_11300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PG910_11310	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PG910_11325	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PG910_11370	COG0464	growth
PG910_11415	COG0584	glycerophosphoryl diester phosphodiesterase
PG910_11420	COG1288	antiporter activity
PG910_11430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PG910_11445	COG1999	signal sequence binding
PG910_11450	COG0750	zinc metalloprotease
PG910_11465	COG0527	aspartate kinase activity
PG910_11475	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PG910_11505	COG0492	ferredoxin-NADP+ reductase activity
PG910_11505	COG3118	belongs to the thioredoxin family
PG910_11510	COG1408	metallophosphoesterase
PG910_11515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PG910_11515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PG910_11530	COG1040	competence protein
PG910_11535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PG910_11555	COG0423	glycine-tRNA ligase activity
PG910_11575	COG2814	Major facilitator Superfamily
PG910_11585	COG1381	Involved in DNA repair and RecF pathway recombination
PG910_11605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PG910_11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PG910_11615	COG2255	four-way junction helicase activity
PG910_11655	COG3474	cytochrome
PG910_11665	COG1253	flavin adenine dinucleotide binding
PG910_11680	COG2151	metal-sulfur cluster biosynthetic enzyme
PG910_11685	COG2166	iron-sulfur cluster assembly
PG910_11695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PG910_11710	COG4771	TonB-dependent receptor
PG910_11730	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PG910_11735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PG910_11745	COG0513	Belongs to the DEAD box helicase family
PG910_11755	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PG910_11760	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PG910_11765	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PG910_11770	COG1805	sodium ion transport
PG910_11775	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PG910_11785	COG2967	ApaG domain
PG910_11810	COG1012	belongs to the aldehyde dehydrogenase family
PG910_11815	COG2066	Belongs to the glutaminase family
PG910_11840	COG0357	Ribosomal RNA small subunit methyltransferase G
PG910_11845	COG3239	Fatty acid desaturase
PG910_11850	COG0436	Aminotransferase
PG910_11865	COG0084	hydrolase, TatD family'
PG910_11875	COG0590	tRNA wobble adenosine to inosine editing
PG910_11890	COG0714	Associated with various cellular activities
PG910_11905	COG2304	oxidoreductase activity
PG910_11910	COG2304	oxidoreductase activity
PG910_11935	COG0659	secondary active sulfate transmembrane transporter activity
PG910_11940	COG0288	reversible hydration of carbon dioxide
PG910_11945	COG0196	riboflavin kinase activity
PG910_11950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PG910_11965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PG910_11970	COG2239	Acts as a magnesium transporter
PG910_11980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PG910_12005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PG910_12010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PG910_12020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PG910_12025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PG910_12030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PG910_12035	COG0356	it plays a direct role in the translocation of protons across the membrane
PG910_12065	COG1388	LysM domain
PG910_12065	COG0791	NLP P60 protein
PG910_12070	COG0708	Exodeoxyribonuclease III
PG910_12085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PG910_12090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PG910_12110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PG910_12120	COG0006	proline dipeptidase activity
PG910_12130	COG0513	Belongs to the DEAD box helicase family
PG910_12140	COG0189	ligase activity
PG910_12160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PG910_12185	COG2095	MarC family integral membrane protein
PG910_12195	COG2356	endonuclease I
PG910_12205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PG910_12210	COG1053	succinate dehydrogenase
PG910_12220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PG910_12220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PG910_12235	COG1505	serine-type exopeptidase activity
PG910_12245	COG3361	conserved protein (COG2071)
PG910_12280	COG1012	belongs to the aldehyde dehydrogenase family
PG910_12305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PG910_12335	COG0756	dUTP diphosphatase activity
PG910_12340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PG910_12355	COG1187	pseudouridine synthase activity
PG910_12370	COG2153	protein acetylation