locus-tag	class	description
F9Y86_00010	ENOG4105CKK	Glycosyl transferase, family 2
F9Y86_00025	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F9Y86_00055	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F9Y86_00070	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F9Y86_00075	ENOG4105C2X	Arabinose 5-phosphate isomerase
F9Y86_00080	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9Y86_00100	ENOG4105DCF	alanine dehydrogenase
F9Y86_00105	ENOG4105K8N	protein family UPF0079, ATPase
F9Y86_00110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9Y86_00115	ENOG4105DCI	Phosphohydrolase
F9Y86_00120	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9Y86_00125	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9Y86_00130	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9Y86_00135	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F9Y86_00145	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F9Y86_00150	ENOG4105CHR	reductase
F9Y86_00205	ENOG4108S2Y	peptide Chain Release factor
F9Y86_00210	ENOG4105E0Y	RtcB Protein
F9Y86_00240	ENOG4107FW0	short-chain dehydrogenase reductase
F9Y86_00255	ENOG4105EUB	pirin domain protein
F9Y86_00260	ENOG4105EUB	pirin domain protein
F9Y86_00285	ENOG4105CGY	Dna recombination protein
F9Y86_00295	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F9Y86_00305	ENOG4105CFI	type iii restriction protein res subunit
F9Y86_00315	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9Y86_00330	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F9Y86_00340	ENOG4108Z03	MAF-like protein
F9Y86_00355	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F9Y86_00360	ENOG4105VEJ	Heat shock protein
F9Y86_00365	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
F9Y86_00370	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F9Y86_00390	ENOG4107Y2X	deaminase
F9Y86_00415	ENOG4105C2C	drug resistance transporter, Bcr CflA
F9Y86_00420	ENOG4105DR9	pseudouridine synthase
F9Y86_00425	ENOG4108VVK	transcriptional Regulator, AsnC
F9Y86_00445	ENOG4107QKV	phosphomannomutase
F9Y86_00450	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F9Y86_00460	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
F9Y86_00465	ENOG4108TZV	Membrane
F9Y86_00475	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F9Y86_00490	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
F9Y86_00535	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
F9Y86_00550	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F9Y86_00560	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F9Y86_00575	ENOG4105EN6	Membrane
F9Y86_00600	ENOG4105C3G	gtp-binding protein
F9Y86_00605	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_00610	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F9Y86_00620	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F9Y86_00625	ENOG4108JQ1	Dehydrogenase
F9Y86_00635	ENOG4105DFA	alanine racemase domain protein
F9Y86_00640	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F9Y86_00645	ENOG4105EYW	Ion transport protein
F9Y86_00650	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F9Y86_00680	ENOG4105D49	3-dehydroquinate synthase
F9Y86_00685	ENOG4105EGS	Mechanosensitive ion channel
F9Y86_00690	ENOG4108RMU	ferritin dps family protein
F9Y86_00720	ENOG4105CPK	Glycosyl transferase (Group 1
F9Y86_00725	ENOG4108HHA	Transketolase
F9Y86_00755	ENOG4105CDU	Replicative dna helicase
F9Y86_00755	ENOG4105CDU	Replicative dna helicase
F9Y86_00765	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
F9Y86_00770	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
F9Y86_00775	ENOG4108KPZ	tonB-dependent Receptor
F9Y86_00780	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
F9Y86_00785	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
F9Y86_00790	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
F9Y86_00800	ENOG4108594	Permease of the drug metabolite transporter
F9Y86_00820	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
F9Y86_00825	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
F9Y86_00830	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
F9Y86_00840	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F9Y86_00845	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F9Y86_00850	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
F9Y86_00855	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F9Y86_00875	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F9Y86_00880	ENOG41090R7	Ferric uptake
F9Y86_00885	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F9Y86_00905	ENOG4105CEI	nitrite reductase
F9Y86_00910	ENOG4105DY8	decarboxylase
F9Y86_00920	ENOG4105C8Y	Acetylornithine aminotransferase
F9Y86_00930	ENOG410836F	Transposase
F9Y86_00935	ENOG4107UNZ	domain protein
F9Y86_00975	ENOG4105CFH	Aspartokinase
F9Y86_00980	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
F9Y86_00985	ENOG4105D98	threonine synthase
F9Y86_00995	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F9Y86_01000	ENOG4108HRK	Histidine kinase
F9Y86_01005	ENOG4105DY9	regulatoR
F9Y86_01020	ENOG4105D3G	Pseudouridine synthase
F9Y86_01025	ENOG4105DEU	major facilitator superfamily
F9Y86_01040	ENOG4105E0X	reductase
F9Y86_01055	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
F9Y86_01090	ENOG4105W5Q	DNA repair protein (RadC
F9Y86_01095	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
F9Y86_01165	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F9Y86_01180	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
F9Y86_01210	ENOG4105CN9	Peptidase m42 family protein
F9Y86_01215	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
F9Y86_01270	ENOG4105C5H	ABC transporter
F9Y86_01280	ENOG4105C1J	atp-dependent rna helicase
F9Y86_01290	ENOG4105C6T	cysteine synthase
F9Y86_01295	ENOG4105D7W	serine acetyltransferase
F9Y86_01300	ENOG4108ZIT	Ferredoxin, 2FE-2S
F9Y86_01305	ENOG4105CAY	ferredoxin--nadp reductase
F9Y86_01310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F9Y86_01320	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F9Y86_01330	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F9Y86_01340	ENOG4105C11	sulfate adenylyltransferase), subunit 2
F9Y86_01345	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
F9Y86_01355	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
F9Y86_01360	ENOG4105C28	cystathionine
F9Y86_01365	ENOG4105CFH	Aspartokinase
F9Y86_01375	ENOG4105CNG	UPF0061 protein
F9Y86_01380	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F9Y86_01385	ENOG4105E0X	reductase
F9Y86_01390	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F9Y86_01410	ENOG4107QQR	Sporulation
F9Y86_01415	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
F9Y86_01445	ENOG4107T31	5'-nucleotidase
F9Y86_01460	ENOG4105EMN	RNA polymerase sigma factor
F9Y86_01480	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
F9Y86_01490	ENOG4105C0H	protease
F9Y86_01495	ENOG4105CHM	Aminotransferase
F9Y86_01500	ENOG4107R0I	Cell wall formation (By similarity)
F9Y86_01515	ENOG4105K3M	)-transporter
F9Y86_01520	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F9Y86_01535	ENOG4105EHZ	conserved protein UCP016719
F9Y86_01560	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
F9Y86_01580	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F9Y86_01640	ENOG4105CJ1	ABC, transporter
F9Y86_01680	ENOG4107YHX	fad dependent oxidoreductase
F9Y86_01685	ENOG4105SYT	Methylenetetrahydrofolate reductase
F9Y86_01690	ENOG4105C3R	Methionine synthase
F9Y86_01695	ENOG4105C3R	Methionine synthase
F9Y86_01700	ENOG4105C84	Histidine ammonia-lyase
F9Y86_01705	ENOG4107ZT5	Thiol disulfide interchange protein
F9Y86_01785	ENOG4105D7A	ATP-binding protein
F9Y86_01790	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
F9Y86_01810	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F9Y86_01820	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F9Y86_01835	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F9Y86_01840	ENOG4105FE9	pseudouridine synthase
F9Y86_01865	ENOG4105CAT	Cytidine monophosphate kinase
F9Y86_01870	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F9Y86_01885	ENOG4105CA0	peroxidase
F9Y86_01900	ENOG4105BZU	Histidine kinase
F9Y86_01910	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F9Y86_01920	ENOG4105C26	Dehydrogenase
F9Y86_01925	ENOG41075H3	AraC family transcriptional regulator
F9Y86_01935	ENOG4108RMU	ferritin dps family protein
F9Y86_01940	ENOG4105C5Q	Transcriptional regulator
F9Y86_01950	ENOG4105CHH	sulfate transporter
F9Y86_01955	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
F9Y86_01960	ENOG4105CXT	aspartate transcarbamylase
F9Y86_01975	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
F9Y86_01995	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F9Y86_02000	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F9Y86_02005	ENOG4105D3G	Pseudouridine synthase
F9Y86_02010	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F9Y86_02015	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F9Y86_02070	ENOG4105ECP	epimerase
F9Y86_02075	ENOG4105I4A	GCN5-related N-acetyltransferase
F9Y86_02080	ENOG4105C7S	Dehydrogenase
F9Y86_02085	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F9Y86_02100	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
F9Y86_02105	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F9Y86_02110	ENOG4105D52	delta-aminolevulinic acid dehydratase
F9Y86_02130	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F9Y86_02145	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
F9Y86_02160	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
F9Y86_02165	ENOG4105CIN	aminoacyl-histidine dipeptidase
F9Y86_02170	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
F9Y86_02175	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F9Y86_02180	ENOG4107RE3	peptidase, S41
F9Y86_02205	ENOG4105CSR	polyphosphate kinase 2
F9Y86_02215	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F9Y86_02220	ENOG4107QJE	Chromosome Partitioning Protein
F9Y86_02225	ENOG4105FA0	parb-like partition protein
F9Y86_02235	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F9Y86_02240	ENOG4105C3F	Signal peptidase i
F9Y86_02255	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
F9Y86_02315	ENOG4105C09	Bile acid
F9Y86_02325	ENOG4105D17	glycoside hydrolase, family 3 domain protein
F9Y86_02340	ENOG4105CSR	polyphosphate kinase 2
F9Y86_02360	ENOG4105DY9	regulatoR
F9Y86_02385	ENOG4108HRK	Histidine kinase
F9Y86_02410	ENOG4105C5W	Aldolase
F9Y86_02415	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
F9Y86_02420	ENOG4105K89	arsenate reductase
F9Y86_02425	ENOG4105E9K	Isocitrate dehydrogenase
F9Y86_02430	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F9Y86_02475	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
F9Y86_02515	ENOG4105KPY	Small multidrug resistance protein
F9Y86_02525	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F9Y86_02530	ENOG4108I9K	permease protein
F9Y86_02535	ENOG4105E0A	ABC, transporter
F9Y86_02540	ENOG4105IIU	Aminopeptidase
F9Y86_02545	ENOG4107SJ9	decarboxylase
F9Y86_02555	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
F9Y86_02560	ENOG4105CBC	glutamate synthase
F9Y86_02565	ENOG41081WG	50s ribosomal protein l31
F9Y86_02585	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
F9Y86_02590	ENOG4105GPY	SprT protein
F9Y86_02595	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
F9Y86_02605	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F9Y86_02610	ENOG4105EGD	dinuclear metal center protein, YbgI family
F9Y86_02625	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
F9Y86_02635	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
F9Y86_02670	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F9Y86_02675	ENOG4105CDV	Ompa motb domain protein
F9Y86_02745	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F9Y86_02755	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F9Y86_02770	ENOG4105BZU	Histidine kinase
F9Y86_02785	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
F9Y86_02800	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F9Y86_02805	ENOG4105KVH	Transcriptional regulator
F9Y86_02815	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
F9Y86_02825	ENOG41083ND	50S ribosomal protein L33
F9Y86_02830	ENOG4105KDC	50s ribosomal protein l28
F9Y86_02835	ENOG4105CEV	competence damage-inducible protein
F9Y86_02840	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
F9Y86_02855	ENOG4105QNR	S1 RNA binding domain protein
F9Y86_02860	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
F9Y86_02865	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F9Y86_02870	ENOG4105E1F	short-chain dehydrogenase reductase
F9Y86_02890	ENOG4105E2X	shikimate dehydrogenase
F9Y86_02910	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F9Y86_02930	ENOG4108JYK	Dehydrogenase
F9Y86_02990	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
F9Y86_03005	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
F9Y86_03010	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F9Y86_03020	ENOG4105SFS	phosphoesterase RecJ domain protein
F9Y86_03030	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F9Y86_03075	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F9Y86_03085	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F9Y86_03095	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
F9Y86_03160	ENOG4105BZU	Histidine kinase
F9Y86_03180	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F9Y86_03185	ENOG4105DFA	alanine racemase domain protein
F9Y86_03190	ENOG4108J59	Extracellular solute-binding protein, family 5
F9Y86_03200	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
F9Y86_03210	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F9Y86_03230	ENOG4105EUJ	GTP cyclohydrolase i
F9Y86_03235	ENOG4105CUT	histidyl-tRNA synthetase
F9Y86_03240	ENOG4107U9T	Pfam:Ribonuclease_BN
F9Y86_03255	ENOG4105DGW	oligopeptidase A
F9Y86_03260	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F9Y86_03270	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9Y86_03275	ENOG4107E2E	PKHD-type hydroxylase
F9Y86_03335	ENOG4105PGM	cation diffusion facilitator family transporter
F9Y86_03355	ENOG4108S4H	thioesterase Superfamily protein
F9Y86_03385	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F9Y86_03395	ENOG410836F	Transposase
F9Y86_03480	ENOG41082EK	Restriction modification system DNA (Specificity
F9Y86_03520	ENOG4105G6Z	alkaline phosphatase
F9Y86_03530	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_03585	ENOG4107S1E	Beta-lactamase
F9Y86_03610	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
F9Y86_03625	ENOG4108UW5	maltose o-acetyltransferase
F9Y86_03645	ENOG4105K56	Transcriptional regulator
F9Y86_03650	ENOG4108ZHJ	Organic hydroperoxide resistance protein
F9Y86_03660	ENOG4108ZHR	arsR family transcriptional regulator
F9Y86_03685	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
F9Y86_03750	ENOG4107P26	
F9Y86_03765	ENOG4107ZT5	Thiol disulfide interchange protein
F9Y86_03810	ENOG4107YZX	Universal stress protein
F9Y86_03830	ENOG4105C58	cytochrome c oxidase accessory protein ccog
F9Y86_03845	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
F9Y86_03855	ENOG4105D4P	Coproporphyrinogen iii oxidase
F9Y86_03860	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F9Y86_03865	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
F9Y86_03870	ENOG4105C59	p-type ATPase
F9Y86_03885	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F9Y86_03890	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F9Y86_03895	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
F9Y86_03900	ENOG4107VNI	ribosomal protein l10
F9Y86_03905	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F9Y86_03910	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F9Y86_03930	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F9Y86_03965	ENOG41083X6	30S ribosomal protein S21
F9Y86_03970	ENOG4105C1G	acyl-Coa dehydrogenase
F9Y86_03980	ENOG4105BZG	amino acid carrier protein
F9Y86_03990	ENOG4107SVH	Potassium channel protein
F9Y86_04025	ENOG4108JJA	ABC, transporter
F9Y86_04050	ENOG4108URH	decarboxylase
F9Y86_04060	ENOG4105CPP	Dehydrogenase, E1 component
F9Y86_04075	ENOG4108RCM	Nitroreductase
F9Y86_04080	ENOG4107RJ1	sodium solute
F9Y86_04095	ENOG4105N14	lysine exporter protein LysE YggA
F9Y86_04100	ENOG4108KB2	LysR family Transcriptional regulator
F9Y86_04110	ENOG4105K63	Thioredoxin
F9Y86_04115	ENOG4105D3R	alkyl hydroperoxide reductase
F9Y86_04120	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
F9Y86_04145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9Y86_04150	ENOG4105EGS	Mechanosensitive ion channel
F9Y86_04155	ENOG4105RHA	ABC transporter, permease
F9Y86_04160	ENOG4108IUX	(ABC) transporter
F9Y86_04175	ENOG4105CHU	acetyl-coa acetyltransferase
F9Y86_04185	ENOG4105C1G	acyl-Coa dehydrogenase
F9Y86_04220	ENOG410836F	Transposase
F9Y86_04255	ENOG4105C3M	thioredoxin reductase
F9Y86_04280	ENOG4105CIG	ABC transporter
F9Y86_04320	ENOG41075H3	AraC family transcriptional regulator
F9Y86_04400	ENOG4105CUZ	uba thif-type nad fad binding protein
F9Y86_04410	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F9Y86_04415	ENOG4105D82	Glutamate dehydrogenase
F9Y86_04420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9Y86_04425	ENOG4105BZU	Histidine kinase
F9Y86_04445	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
F9Y86_04450	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F9Y86_04460	ENOG4105WH1	Two component transcriptional regulator luxr family
F9Y86_04470	ENOG4105BZU	Histidine kinase
F9Y86_04480	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F9Y86_04485	ENOG4105BZ1	(ABC) transporter
F9Y86_04495	ENOG4105C8B	TIGR00159 family
F9Y86_04500	ENOG4105EEI	dihydropteroate synthase
F9Y86_04515	ENOG41083GQ	Protein CrcB homolog
F9Y86_04545	ENOG4105DBI	uridine monophosphokinase
F9Y86_04555	ENOG4105CMN	Methylmalonyl-coA mutase
F9Y86_04565	ENOG4105D5P	Methylmalonyl-coA mutase
F9Y86_04570	ENOG4105DJ4	phosphatidylserine decarboxylase
F9Y86_04575	ENOG4105CRE	cytochrome C
F9Y86_04590	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
F9Y86_04595	ENOG4105E6M	Sulphatase-modifying factor protein
F9Y86_04605	ENOG4105KG3	cytidine deaminase
F9Y86_04610	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F9Y86_04615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F9Y86_04620	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F9Y86_04625	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
F9Y86_04630	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F9Y86_04635	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
F9Y86_04640	ENOG4105ESV	Glycosyl transferase, family 4
F9Y86_04645	ENOG4108TJN	glycosyl transferase group 1
F9Y86_04650	ENOG4105CPK	Glycosyl transferase (Group 1
F9Y86_04655	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
F9Y86_04680	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
F9Y86_04685	ENOG4105J5G	Transferase hexapeptide repeat containing protein
F9Y86_04690	ENOG4107R5Z	Oxidoreductase domain protein
F9Y86_04695	ENOG4107QQG	Dehydrogenase
F9Y86_04720	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F9Y86_04725	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
F9Y86_04735	ENOG4109015	Biopolymer transport protein exbD tolR
F9Y86_04755	ENOG4105C1G	acyl-Coa dehydrogenase
F9Y86_04760	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F9Y86_04765	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F9Y86_04770	ENOG4105C6K	Malic enzyme
F9Y86_04835	ENOG4105BZU	Histidine kinase
F9Y86_04840	ENOG4105C22	threonyL-tRNA synthetase
F9Y86_04845	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F9Y86_04850	ENOG4105VJV	50s ribosomal protein L35
F9Y86_04855	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
F9Y86_04870	ENOG4105CKU	formyltetrahydrofolate synthetase
F9Y86_04875	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F9Y86_04880	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F9Y86_04885	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F9Y86_04905	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_04915	ENOG4105C2F	Histidine kinase
F9Y86_04925	ENOG4108QBX	(LipO)protein
F9Y86_04930	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9Y86_04940	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
F9Y86_04950	ENOG4105CN1	protease
F9Y86_04995	ENOG4105CRK	lysyL-tRNA synthetase
F9Y86_05000	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
F9Y86_05005	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F9Y86_05010	ENOG4105DUX	Transporter
F9Y86_05015	ENOG4105DUX	Transporter
F9Y86_05020	ENOG4105C5Z	peptidase
F9Y86_05035	ENOG4105CBX	hi0933 family
F9Y86_05075	ENOG4105FE9	pseudouridine synthase
F9Y86_05235	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9Y86_05265	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F9Y86_05270	ENOG4105DFF	Rod shape-determining protein mreb
F9Y86_05285	ENOG4105CJN	penicillin-binding protein
F9Y86_05290	ENOG4105CNI	cell division protein FtsW
F9Y86_05295	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
F9Y86_05310	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F9Y86_05325	ENOG41083MR	nifu domain-containing protein
F9Y86_05330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F9Y86_05355	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9Y86_05360	ENOG4105DJV	ribulose-phosphate 3-epimerase
F9Y86_05365	ENOG41080XP	Cbs domain
F9Y86_05380	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F9Y86_05385	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F9Y86_05410	ENOG4108NEV	two component transcriptional regulator, LytTR family
F9Y86_05415	ENOG4108HRK	Histidine kinase
F9Y86_05445	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_05460	ENOG4105KTH	gatB Yqey
F9Y86_05465	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F9Y86_05470	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F9Y86_05480	ENOG4105DFU	Cell wall formation (By similarity)
F9Y86_05485	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F9Y86_05495	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F9Y86_05505	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
F9Y86_05510	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F9Y86_05515	ENOG4105CJN	penicillin-binding protein
F9Y86_05525	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F9Y86_05530	ENOG4107YM1	mraZ protein
F9Y86_05540	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F9Y86_05545	ENOG4108YBP	pseudouridine synthase
F9Y86_05550	ENOG4105EEF	Alkane 1-monooxygenase
F9Y86_05555	ENOG4105C26	Dehydrogenase
F9Y86_05600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9Y86_05605	ENOG4105BZU	Histidine kinase
F9Y86_05625	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F9Y86_05635	ENOG4105CUY	Mechanosensitive ion channel
F9Y86_05640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F9Y86_05670	ENOG4105KBX	Transcriptional regulator, TetR family
F9Y86_05675	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F9Y86_05705	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F9Y86_05710	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F9Y86_05725	ENOG4105UYK	outer membrane protein a
F9Y86_05730	ENOG4107RAN	Peptidase, M16
F9Y86_05745	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_05795	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
F9Y86_05800	ENOG4105C28	cystathionine
F9Y86_05805	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F9Y86_05810	ENOG4105DFD	Na H antiporter
F9Y86_05830	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F9Y86_05840	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
F9Y86_05845	ENOG4108MK9	spermidine N(1)-acetyltransferase
F9Y86_05850	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F9Y86_05855	ENOG4105K5M	30s ribosomal protein S16
F9Y86_05860	ENOG4105VEQ	Cold shock protein
F9Y86_05865	ENOG4105C0B	DNA polymerase III (alpha subunit)
F9Y86_05960	ENOG4105CJ1	ABC, transporter
F9Y86_05970	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
F9Y86_05980	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
F9Y86_05990	ENOG4105D9N	nucleoside
F9Y86_06000	ENOG4105C10	Electron transfer flavoprotein
F9Y86_06005	ENOG4105BZJ	Electron transfer flavoprotein
F9Y86_06010	ENOG4105CPP	Dehydrogenase, E1 component
F9Y86_06020	ENOG4105F0N	pyrophosphate phospho-hydrolase
F9Y86_06025	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F9Y86_06030	ENOG4105CRQ	synthase (Component I)
F9Y86_06040	ENOG4105E5G	Alpha beta hydrolase fold
F9Y86_06045	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F9Y86_06050	ENOG4107QIV	Cytochrome c biogenesis protein
F9Y86_06065	ENOG4105C0P	Mg chelatase subunit ChlI
F9Y86_06070	ENOG4107ZT5	Thiol disulfide interchange protein
F9Y86_06080	ENOG41090A1	ferritin
F9Y86_06085	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
F9Y86_06100	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
F9Y86_06135	ENOG4107QX3	carboxylase
F9Y86_06140	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F9Y86_06160	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9Y86_06165	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9Y86_06170	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9Y86_06175	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9Y86_06185	ENOG4105CA0	peroxidase
F9Y86_06205	ENOG4105NWN	ApaG protein
F9Y86_06235	ENOG4105C26	Dehydrogenase
F9Y86_06240	ENOG4108UK2	deaminase
F9Y86_06245	ENOG4105CSV	Glutaminase
F9Y86_06255	ENOG4105C1J	atp-dependent rna helicase
F9Y86_06260	ENOG41080HT	Transcriptional regulator, arsr family
F9Y86_06275	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F9Y86_06285	ENOG4105CHM	Aminotransferase
F9Y86_06290	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F9Y86_06295	ENOG4107TPS	domain protein
F9Y86_06305	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F9Y86_06310	ENOG4105BZ9	Cytochrome C oxidase, subunit I
F9Y86_06340	ENOG4107SFQ	iron-sulfur binding
F9Y86_06355	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F9Y86_06365	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
F9Y86_06370	ENOG4105VG1	fes assembly suf system protein
F9Y86_06410	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F9Y86_06415	ENOG4108RG0	uracil-dna glycosylase
F9Y86_06425	ENOG4105C1J	atp-dependent rna helicase
F9Y86_06440	ENOG4105F8V	Hydrolase, tatD family
F9Y86_06450	ENOG4108Z6B	deaminase
F9Y86_06455	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
F9Y86_06460	ENOG4107RNH	Outer membrane receptor FepA
F9Y86_06470	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_06475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F9Y86_06490	ENOG4107QVM	von Willebrand factor, type A
F9Y86_06495	ENOG4107QVM	von Willebrand factor, type A
F9Y86_06545	ENOG4105CHR	reductase
F9Y86_06555	ENOG41080R2	UPF0102 protein
F9Y86_06565	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
F9Y86_06570	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F9Y86_06580	ENOG4105BZM	domain protein
F9Y86_06595	ENOG4108UUM	single-stranded DNA-binding protein
F9Y86_06610	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F9Y86_06630	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F9Y86_06635	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F9Y86_06640	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F9Y86_06645	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F9Y86_06650	ENOG4108B1Q	Ribonuclease
F9Y86_06670	ENOG4105D64	Mechanosensitive ion channel
F9Y86_06675	ENOG41072GX	Peptidase M22 Glycoprotease
F9Y86_06690	ENOG4108SJC	Membrane
F9Y86_06695	ENOG4108KF3	Electron transport protein SCO1 SenC
F9Y86_06710	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
F9Y86_06715	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
F9Y86_06720	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
F9Y86_06760	ENOG4105C72	UPF0176 protein
F9Y86_06775	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F9Y86_06780	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
F9Y86_06790	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F9Y86_06800	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
F9Y86_06805	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F9Y86_06810	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
F9Y86_06820	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F9Y86_06840	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F9Y86_06850	ENOG4105BZG	amino acid carrier protein
F9Y86_06860	ENOG4105C9M	aspartyl-trna synthetase
F9Y86_06870	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
F9Y86_06875	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
F9Y86_06890	ENOG4105C9B	Cysteine desulfurase
F9Y86_06905	ENOG4108KF3	Electron transport protein SCO1 SenC
F9Y86_06910	ENOG4105DZP	Membrane-associated zinc metalloprotease
F9Y86_06920	ENOG4108EV3	Bifunctional aspartate kinase II homoserine dehydrogenase II
F9Y86_06930	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F9Y86_06935	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F9Y86_06945	ENOG4108IG5	Transcriptional regulator
F9Y86_06950	ENOG4105C28	cystathionine
F9Y86_06990	ENOG4105K63	Thioredoxin
F9Y86_07000	ENOG4105C2M	dna polymerase I
F9Y86_07005	ENOG4105D29	Helix-turn-helix type 11 domain protein
F9Y86_07025	ENOG4105MJ2	Competence protein
F9Y86_07045	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
F9Y86_07065	ENOG4105DTN	riboflavin biosynthesis protein ribF
F9Y86_07075	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F9Y86_07095	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F9Y86_07100	ENOG4105CJW	magnesium transporter
F9Y86_07135	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F9Y86_07150	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F9Y86_07155	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F9Y86_07160	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F9Y86_07165	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
F9Y86_07175	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
F9Y86_07220	ENOG4105CGK	Exodeoxyribonuclease III
F9Y86_07230	ENOG4107QP7	CoA-transferase subunit A
F9Y86_07235	ENOG4108JQC	penicillin-binding protein 1A
F9Y86_07240	ENOG410647Z	gliding motility-associated lipoprotein GldH
F9Y86_07245	ENOG4105MA4	psp1 domain protein
F9Y86_07250	ENOG4105CX6	glutaminyL-tRNA synthetase
F9Y86_07270	ENOG4105C8F	Beta-lactamase domain protein
F9Y86_07290	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9Y86_07300	ENOG4105C1J	atp-dependent rna helicase
F9Y86_07310	ENOG4107T6F	Xaa-Pro aminopeptidase
F9Y86_07395	ENOG4105DWV	Homoserine O-trans-acetylase
F9Y86_07415	ENOG4105E33	succinate dehydrogenase
F9Y86_07430	ENOG4105EMU	Dehydrogenase
F9Y86_07455	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F9Y86_07475	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9Y86_07485	ENOG4105C9K	Endothelin-converting enzyme 1
F9Y86_07495	ENOG4105NGQ	Thioredoxin
F9Y86_07505	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F9Y86_07520	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F9Y86_07530	ENOG4108K8S	endonuclease I
F9Y86_07535	ENOG4108NEV	two component transcriptional regulator, LytTR family
F9Y86_07555	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
F9Y86_07590	ENOG4105EMN	RNA polymerase sigma factor
F9Y86_07600	ENOG4105D44	asparaginase
F9Y86_07605	ENOG4105C26	Dehydrogenase
F9Y86_07620	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F9Y86_07625	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
F9Y86_07630	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F9Y86_07645	ENOG4107YB6	acetyltransferase, (GNAT) family
F9Y86_07650	ENOG4108YZG	isomerase
F9Y86_07660	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F9Y86_07675	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F9Y86_07680	ENOG4105K8R	UPF0145 protein
F9Y86_07695	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
F9Y86_07700	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
F9Y86_07705	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F9Y86_07725	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F9Y86_07765	ENOG4108JA2	transcriptioN-repair coupling factor
F9Y86_07770	ENOG41082IR	Excinuclease ABC C subunit domain protein
F9Y86_07775	ENOG4108UZ3	Transporter
F9Y86_07800	ENOG4105DSF	transport protein
F9Y86_07820	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
F9Y86_07845	ENOG4105CYP	glycoside hydrolase, family
F9Y86_07850	ENOG4105C5H	ABC transporter
F9Y86_07865	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F9Y86_07870	ENOG4105BZU	Histidine kinase
F9Y86_07875	ENOG4107QNG	Phosphoribosylglycinamide synthetase
F9Y86_07885	ENOG4105CN1	protease
F9Y86_07890	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F9Y86_07905	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
F9Y86_07915	ENOG4105BZU	Histidine kinase
F9Y86_07920	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F9Y86_07925	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
F9Y86_07930	ENOG4105EUJ	GTP cyclohydrolase i
F9Y86_07950	ENOG4108IPT	Naphthoate synthase
F9Y86_07975	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
F9Y86_07980	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F9Y86_07985	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
F9Y86_07990	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F9Y86_08000	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
F9Y86_08025	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F9Y86_08030	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F9Y86_08035	ENOG4105D78	K07001 NTE family protein
F9Y86_08040	ENOG4105C03	ribonuclease
F9Y86_08045	ENOG4105K70	DNA-binding protein
F9Y86_08065	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_08070	ENOG4105CEN	a g-specific adenine glycosylase
F9Y86_08075	ENOG4108UUM	single-stranded DNA-binding protein
F9Y86_08115	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
F9Y86_08120	ENOG4105K46	50S ribosomal protein l27
F9Y86_08125	ENOG4105DY9	regulatoR
F9Y86_08145	ENOG4105CFP	Peptidase U32
F9Y86_08155	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F9Y86_08165	ENOG4105E39	Enoyl-CoA hydratase
F9Y86_08180	ENOG4107QRG	dna polymerase iii
F9Y86_08190	ENOG4105CE1	Ferrous iron transport protein b
F9Y86_08215	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
F9Y86_08230	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F9Y86_08255	ENOG4105CAY	ferredoxin--nadp reductase
F9Y86_08265	ENOG4108ZIT	Ferredoxin, 2FE-2S
F9Y86_08270	ENOG4105DY8	decarboxylase
F9Y86_08275	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
F9Y86_08295	ENOG4105DUU	IucA IucC family protein
F9Y86_08345	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_08360	ENOG4105F1J	Homogentisate 1,2-dioxygenase
F9Y86_08365	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
F9Y86_08385	ENOG4107QP8	phosphohexose isomerase
F9Y86_08390	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_08430	ENOG4108ZAF	Molybdopterin
F9Y86_08435	ENOG4105BZA	Phosphoglycerate kinase
F9Y86_08440	ENOG4105CPC	Aldo Keto reductase
F9Y86_08455	ENOG4105C31	Tryptophanyl-tRNA synthetase
F9Y86_08465	ENOG4108UT2	hemolysin iii
F9Y86_08475	ENOG41080ZE	Adenylate cyclase
F9Y86_08480	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
F9Y86_08485	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F9Y86_08490	ENOG4105VCH	membrane
F9Y86_08510	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
F9Y86_08515	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
F9Y86_08520	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
F9Y86_08525	ENOG4105C6K	Malic enzyme
F9Y86_08530	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
F9Y86_08540	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F9Y86_08560	ENOG4105J5G	Transferase hexapeptide repeat containing protein
F9Y86_08570	ENOG4105CND	Glycosyl transferase, family 2
F9Y86_08610	ENOG4105CZH	peptidase
F9Y86_08635	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_08655	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
F9Y86_08665	ENOG4105CD3	dihydroorotase
F9Y86_08680	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F9Y86_08700	ENOG4105CA0	peroxidase
F9Y86_08725	ENOG4105C8T	Leucyl-tRNA synthetase
F9Y86_08750	ENOG4105C29	acyl-CoA thioesterase
F9Y86_08795	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F9Y86_08810	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
F9Y86_08815	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F9Y86_08820	ENOG4107T8J	thymidine kinase
F9Y86_08840	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
F9Y86_08845	ENOG4105CHV	Transcription elongation factor NusA
F9Y86_08850	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
F9Y86_08875	ENOG4108JQ1	Dehydrogenase
F9Y86_08880	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
F9Y86_08925	ENOG4105D05	Receptor
F9Y86_08945	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F9Y86_08950	ENOG4105CDV	Ompa motb domain protein
F9Y86_08955	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F9Y86_08965	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F9Y86_09010	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F9Y86_09025	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F9Y86_09035	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F9Y86_09045	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F9Y86_09080	ENOG4105CNA	YD repeat protein
F9Y86_09090	ENOG4105CNA	YD repeat protein
F9Y86_09145	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
F9Y86_09150	ENOG4105C7S	Dehydrogenase
F9Y86_09165	ENOG4105NIV	Esterase
F9Y86_09195	ENOG4108Z4V	iron-sulfur cluster assembly
F9Y86_09220	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
F9Y86_09225	ENOG4109066	lysm domain bon superfamily protein
F9Y86_09235	ENOG4105DSJ	YicC domain protein
F9Y86_09240	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
F9Y86_09245	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
F9Y86_09250	ENOG4108K5P	(LipO)protein
F9Y86_09260	ENOG4108RPX	mosc domain containing protein
F9Y86_09275	ENOG4105CN1	protease
F9Y86_09290	ENOG4108VVK	transcriptional Regulator, AsnC
F9Y86_09295	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F9Y86_09300	ENOG4105KT5	UmuD protein
F9Y86_09305	ENOG4108Y6J	UPF0403 protein
F9Y86_09310	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
F9Y86_09315	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
F9Y86_09320	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F9Y86_09340	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
F9Y86_09360	ENOG4105MD1	YeeE YedE family protein
F9Y86_09365	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F9Y86_09370	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F9Y86_09375	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F9Y86_09380	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F9Y86_09385	ENOG4105WXV	50S ribosomal protein L32
F9Y86_09395	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F9Y86_09400	ENOG4108R6K	riboflavin synthase, subunit alpha
F9Y86_09445	ENOG4108JGH	Tetr family transcriptional regulator
F9Y86_09475	ENOG4105EXW	epimerase dehydratase
F9Y86_09490	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
F9Y86_09495	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
F9Y86_09505	ENOG4107RJ9	Cell division protein FtsX
F9Y86_09510	ENOG4108ZVT	methylmalonyl-coA epimerase
F9Y86_09535	ENOG4105ENE	Histidine kinase
F9Y86_09545	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F9Y86_09550	ENOG4105D60	lipoprotein releasing system transmembrane protein
F9Y86_09555	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F9Y86_09575	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
F9Y86_09585	ENOG4105HDK	L-asparaginase
F9Y86_09620	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9Y86_09625	ENOG4105C5S	asparaginyl-tRNA synthetase
F9Y86_09635	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
F9Y86_09640	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
F9Y86_09645	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F9Y86_09650	ENOG4105CE9	30S ribosomal protein S2
F9Y86_09655	ENOG4108UJD	30S ribosomal protein S9
F9Y86_09660	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F9Y86_09665	ENOG4107RNH	Outer membrane receptor FepA
F9Y86_09675	ENOG4105CJ2	(LipO)protein
F9Y86_09680	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F9Y86_09695	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F9Y86_09705	ENOG4108K0D	peptidase, M48
F9Y86_09735	ENOG4105EWK	phytoene
F9Y86_09780	ENOG4105CGD	Nad-dependent epimerase dehydratase
F9Y86_09795	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
F9Y86_09800	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F9Y86_09820	ENOG4105EUJ	GTP cyclohydrolase i
F9Y86_09830	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
F9Y86_09840	ENOG4108V06	Glutathione peroxidase
F9Y86_09865	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F9Y86_09975	ENOG4108NEV	two component transcriptional regulator, LytTR family
F9Y86_10000	ENOG4105M08	Membrane
F9Y86_10010	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F9Y86_10015	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
F9Y86_10040	ENOG4105CNM	Receptor
F9Y86_10060	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F9Y86_10070	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F9Y86_10205	ENOG4105DY9	regulatoR
F9Y86_10230	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9Y86_10235	ENOG41083X6	30S ribosomal protein S21
F9Y86_10245	ENOG4105CH2	amidohydrolase
F9Y86_10250	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F9Y86_10255	ENOG4106M28	alanine racemase domain protein
F9Y86_10265	ENOG4105CIF	Ornithine Cyclodeaminase
F9Y86_10270	ENOG4105CTU	Proline racemase
F9Y86_10275	ENOG4105DC7	peptidase M24
F9Y86_10280	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F9Y86_10285	ENOG4105CTU	Proline racemase
F9Y86_10295	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F9Y86_10300	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
F9Y86_10310	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
F9Y86_10325	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9Y86_10330	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
F9Y86_10340	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
F9Y86_10350	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
F9Y86_10355	ENOG4105EV9	Alpha Beta Hydrolase
F9Y86_10380	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
F9Y86_10390	ENOG41086DT	Membrane protein of unknown function
F9Y86_10395	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F9Y86_10405	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F9Y86_10415	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
F9Y86_10420	ENOG4107RW9	nh(3)-dependent nad( ) synthetase
F9Y86_10440	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
F9Y86_10445	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F9Y86_10450	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F9Y86_10455	ENOG4105D2N	Aldolase
F9Y86_10465	ENOG4108RWN	rrna methyltransferase
F9Y86_10480	ENOG4105ZMH	deoxynucleoside kinase
F9Y86_10490	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F9Y86_10500	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
F9Y86_10505	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F9Y86_10510	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
F9Y86_10520	ENOG4105CHM	Aminotransferase
F9Y86_10545	ENOG4105K63	Thioredoxin
F9Y86_10550	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F9Y86_10570	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F9Y86_10585	ENOG4105EMU	Dehydrogenase
F9Y86_10600	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F9Y86_10615	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F9Y86_10620	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
F9Y86_10625	ENOG4108S4H	thioesterase Superfamily protein
F9Y86_10630	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
F9Y86_10640	ENOG4105CEP	NADH dehydrogenase
F9Y86_10655	ENOG4105M08	Membrane
F9Y86_10660	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
F9Y86_10665	ENOG4105CPN	adenine deaminase
F9Y86_10670	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
F9Y86_10675	ENOG4105CSA	Coproporphyrinogen iii oxidase
F9Y86_10705	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
F9Y86_10710	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F9Y86_10715	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
F9Y86_10735	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F9Y86_10740	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F9Y86_10760	ENOG4108JUA	Transcriptional regulator
F9Y86_10765	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F9Y86_10780	ENOG4105E6M	Sulphatase-modifying factor protein
F9Y86_10810	ENOG4105C5H	ABC transporter
F9Y86_10830	ENOG4105K4H	Nlp p60 protein
F9Y86_10845	ENOG4108HRK	Histidine kinase
F9Y86_10850	ENOG4105DY9	regulatoR
F9Y86_10855	ENOG4108Z0R	Transferase
F9Y86_10885	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9Y86_10900	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
F9Y86_10925	ENOG4105C37	(CBS) domain
F9Y86_10940	ENOG4107QN2	dihydrolipoyl dehydrogenase
F9Y86_10975	ENOG4105DGW	oligopeptidase A
F9Y86_10980	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F9Y86_10985	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F9Y86_10995	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F9Y86_11010	ENOG4105BZU	Histidine kinase
F9Y86_11035	ENOG4105DZ0	fad dependent oxidoreductase
F9Y86_11040	ENOG4105CRW	Short chain fatty acid transporter
F9Y86_11045	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
F9Y86_11115	ENOG4105CCT	upf0313 protein
F9Y86_11125	ENOG41075SV	phosphoribosyltransferase
F9Y86_11145	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
F9Y86_11155	ENOG4108UVJ	appr-1-p processing domain protein
F9Y86_11165	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F9Y86_11175	ENOG4108AEY	RNA polymerase sigma factor
F9Y86_11185	ENOG4105EFZ	amidohydrolase
F9Y86_11210	ENOG4105CAK	Cell division ATP-binding protein ftsE
F9Y86_11230	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F9Y86_11240	ENOG4105CAQ	asparagine synthetase
F9Y86_11250	ENOG4105CRQ	synthase (Component I)
F9Y86_11255	ENOG4105DDQ	anthranilate synthase
F9Y86_11260	ENOG4107RI6	Anthranilate phosphoribosyltransferase
F9Y86_11270	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F9Y86_11275	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
F9Y86_11280	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F9Y86_11285	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F9Y86_11290	ENOG4107RE3	peptidase, S41
F9Y86_11300	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9Y86_11325	ENOG4105D5P	Methylmalonyl-coA mutase
F9Y86_11335	ENOG4105CGP	Urocanate hydratase
F9Y86_11355	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
F9Y86_11360	ENOG4105DY9	regulatoR
F9Y86_11365	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_11375	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_11385	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
F9Y86_11390	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F9Y86_11400	ENOG4105CP7	Triose-phosphate isomerase
F9Y86_11405	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F9Y86_11410	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
F9Y86_11455	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
F9Y86_11475	ENOG4105D7N	magnesium and cobalt transport protein CorA
F9Y86_11485	ENOG4108IJF	Heavy metal efflux pump, CzcA
F9Y86_11495	ENOG4105C59	p-type ATPase
F9Y86_11505	ENOG4105CZ9	Domain of unknown function (DU1801)
F9Y86_11510	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
F9Y86_11545	ENOG4107R5B	glutamine synthetase
F9Y86_11575	ENOG4105P8Q	Curli production assembly transport component CsgG
F9Y86_11585	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F9Y86_11595	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F9Y86_11600	ENOG41083X6	30S ribosomal protein S21
F9Y86_11605	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F9Y86_11625	ENOG4105CHR	reductase
F9Y86_11635	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
F9Y86_11645	ENOG4108RCM	Nitroreductase
F9Y86_11650	ENOG4105KVH	Transcriptional regulator
F9Y86_11655	ENOG4105NF4	modulator of drug activity
F9Y86_11680	ENOG4105CZH	peptidase
F9Y86_11755	ENOG4105W5Q	DNA repair protein (RadC
F9Y86_11805	ENOG4105VRT	cytoplasmic protein
F9Y86_11815	ENOG4105CT7	inner membrane cred family protein
F9Y86_11845	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
F9Y86_11855	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
F9Y86_11880	ENOG4107S85	alpha-2-macroglobulin domain protein
F9Y86_11885	ENOG4105DFU	Cell wall formation (By similarity)
F9Y86_11915	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F9Y86_11920	ENOG4105C1A	potassium transporter peripheral membrane
F9Y86_11925	ENOG4105W5Q	DNA repair protein (RadC
F9Y86_11955	ENOG4105HMI	Membrane
F9Y86_11960	ENOG4105DUM	transcriptional regulator, lysR family
F9Y86_11965	ENOG4105D1H	recombination factor protein RarA
F9Y86_11975	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F9Y86_11985	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_11995	ENOG4105C27	TonB-dependent Receptor Plug
F9Y86_12000	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
F9Y86_12005	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F9Y86_12010	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F9Y86_12015	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F9Y86_12020	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F9Y86_12025	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F9Y86_12030	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F9Y86_12035	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F9Y86_12040	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F9Y86_12045	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F9Y86_12050	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
F9Y86_12055	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F9Y86_12060	ENOG4105WNB	50s ribosomal protein l29
F9Y86_12065	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
F9Y86_12070	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
F9Y86_12075	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F9Y86_12080	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F9Y86_12085	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F9Y86_12090	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F9Y86_12095	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
F9Y86_12100	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
F9Y86_12105	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
F9Y86_12110	ENOG41084HK	50S ribosomal protein L30
F9Y86_12115	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F9Y86_12125	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
F9Y86_12130	ENOG410864M	50S ribosomal protein L36
F9Y86_12135	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F9Y86_12140	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
F9Y86_12145	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F9Y86_12150	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F9Y86_12155	ENOG4108ZT0	50S ribosomal protein l17
F9Y86_12160	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
F9Y86_12165	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
F9Y86_12190	ENOG41066UZ	arginase EC 3.5.3.1
F9Y86_12195	ENOG4105WHD	thiamine biosynthesis protein ThiS
F9Y86_12205	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F9Y86_12210	ENOG4105DWF	phosphomethylpyrimidine kinase
F9Y86_12215	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F9Y86_12220	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F9Y86_12225	ENOG4105D41	biosynthesis protein thiH
F9Y86_12240	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F9Y86_12250	ENOG4105EMN	RNA polymerase sigma factor
F9Y86_12265	ENOG4105C8N	cysteinyl-tRNA synthetase
F9Y86_12270	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F9Y86_12275	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
F9Y86_12285	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F9Y86_12320	ENOG41075H3	AraC family transcriptional regulator
F9Y86_12325	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9Y86_12340	ENOG4107SN7	NLP P60 protein
F9Y86_12345	ENOG4105CHU	acetyl-coa acetyltransferase
F9Y86_12380	ENOG4107RT3	EamA-like transporter family
F9Y86_12385	ENOG4105ID8	Transcriptional regulator, ARAC family
F9Y86_12390	ENOG4108XI2	Domain of unknown function (DUF1963)
F9Y86_12405	ENOG4105C5H	ABC transporter
F9Y86_12410	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F9Y86_12420	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F9Y86_12430	ENOG4108JQ1	Dehydrogenase
F9Y86_12450	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
F9Y86_12460	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
F9Y86_12475	ENOG41087YS	Phage shock protein A
F9Y86_12490	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F9Y86_12515	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
F9Y86_12520	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
F9Y86_12545	ENOG4108JJA	ABC, transporter
F9Y86_12555	ENOG4105DUX	Transporter
F9Y86_12570	ENOG4105KNE	Phosphatidate cytidylyltransferase
F9Y86_12580	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F9Y86_12585	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
F9Y86_12600	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
F9Y86_12605	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F9Y86_12610	ENOG4105CFG	Acts as a chaperone (By similarity)
F9Y86_12630	ENOG4108NEV	two component transcriptional regulator, LytTR family
F9Y86_12635	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
F9Y86_12675	ENOG4105D6A	Electron transport complex
F9Y86_12705	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
F9Y86_12720	ENOG4105ENX	hydrolase
F9Y86_12755	ENOG4105F27	Major Facilitator
F9Y86_12770	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F9Y86_12785	ENOG4105CNU	cell division protein FtsK
F9Y86_12795	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
F9Y86_12800	ENOG4107QI1	Mate efflux family protein
F9Y86_12830	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
F9Y86_12850	ENOG4105CQB	FAD linked oxidase domain protein
F9Y86_12860	ENOG4105E32	cytoplasmic protein
F9Y86_12870	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F9Y86_12895	ENOG4105CJ1	ABC, transporter
F9Y86_12915	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F9Y86_12925	ENOG4105VIE	preprotein translocase, subunit YajC
F9Y86_12935	ENOG4107R6T	Involved in the transcription termination process (By similarity)
F9Y86_12940	ENOG4107RDP	Dehydrogenase
F9Y86_12945	ENOG4105BZ1	(ABC) transporter
F9Y86_12955	ENOG4105E4F	Isochorismate synthase
F9Y86_12965	ENOG4105KA0	thioesterase Superfamily protein
F9Y86_12975	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
F9Y86_13005	ENOG4105CUB	amino acid
F9Y86_13010	ENOG4105DSQ	Nitric oxide reductase
F9Y86_13015	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
F9Y86_13020	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
F9Y86_13045	ENOG4105FJR	Lmbe family
F9Y86_13105	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F9Y86_13120	ENOG4105E7U	AraC family transcriptional regulator
F9Y86_13145	ENOG4105F0I	Aminotransferase
F9Y86_13150	ENOG4108UJU	UPF0301 protein
F9Y86_13155	ENOG4105DY9	regulatoR
F9Y86_13160	ENOG4108HRK	Histidine kinase
F9Y86_13210	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F9Y86_13225	ENOG4105DU6	RNA polymerase
F9Y86_13230	ENOG4105CSM	endonuclease III
F9Y86_13235	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9Y86_13255	ENOG4105CD3	dihydroorotase
F9Y86_13270	ENOG41074B2	UPF0747 protein
F9Y86_13275	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
F9Y86_13295	ENOG4105C98	muts2 protein
F9Y86_13300	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
F9Y86_13315	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F9Y86_13325	ENOG4108WBT	adenosyltransferase
F9Y86_13335	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F9Y86_13345	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
F9Y86_13355	ENOG4105HHA	aminodeoxychorismate lyase
F9Y86_13365	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
F9Y86_13370	ENOG4105C0H	protease
F9Y86_13390	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F9Y86_13420	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F9Y86_13425	ENOG41090A1	ferritin
F9Y86_13450	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F9Y86_13460	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
F9Y86_13470	ENOG4107XZA	Glycosyl transferase family 2
F9Y86_13475	ENOG4107RAN	Peptidase, M16
F9Y86_13480	ENOG41086IN	PA14
F9Y86_13515	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
F9Y86_13525	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F9Y86_13535	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
F9Y86_13545	ENOG4105DG6	mannose-6-phosphate isomerase
F9Y86_13555	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F9Y86_13560	ENOG4105U0R	haloacid dehalogenase-like hydrolase
F9Y86_13590	ENOG4105JVQ	RNA Polymerase
F9Y86_13600	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F9Y86_13605	ENOG4105D1Q	UPF0246 protein
F9Y86_13610	ENOG4108UB4	uncharacterized protein ygjQ
F9Y86_13615	ENOG4105EJQ	L-serine dehydratase
F9Y86_13630	ENOG4105CK7	Sodium proline symporter
F9Y86_13635	ENOG4105CTQ	phosphohexokinase
F9Y86_13640	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F9Y86_13645	ENOG4108Z5K	methylglyoxal synthase
F9Y86_13655	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
F9Y86_13660	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F9Y86_13670	ENOG4105DF6	Fe-S oxidoreductase
F9Y86_13675	ENOG4105DF6	Fe-S oxidoreductase
F9Y86_13685	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
F9Y86_13695	ENOG4107W2A	UPF0173 metal-dependent hydrolase
F9Y86_13705	ENOG4105DTQ	mandelate racemase muconate lactonizing
F9Y86_13710	ENOG4107FCW	Abortive infection protein
F9Y86_13720	ENOG4105CP2	von willebrand factor, type a
F9Y86_13725	ENOG4105CDY	transcriptional regulatory protein
F9Y86_13735	ENOG4107QX3	carboxylase
F9Y86_13745	ENOG4107QP3	malate synthase g
F9Y86_13750	ENOG4107RET	Isocitrate lyase
F9Y86_13795	ENOG41067TZ	transcriptional regulator, MarR family
F9Y86_13805	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F9Y86_13815	ENOG4105C5H	ABC transporter
F9Y86_13830	ENOG4107QN2	dihydrolipoyl dehydrogenase
F9Y86_13835	ENOG4105C75	arginyL-tRNA synthetase
F9Y86_13885	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F9Y86_13895	ENOG4105EA8	2-Nitropropane dioxygenase
F9Y86_13905	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F9Y86_13910	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F9Y86_13915	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F9Y86_13920	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F9Y86_13935	ENOG4108HRK	Histidine kinase
F9Y86_13940	ENOG4108VAC	response regulator
F9Y86_13950	ENOG4105CHR	reductase
F9Y86_13955	ENOG4105VSH	4-oxalocrotonate tautomerase
F9Y86_14010	ENOG41088SP	formiminoglutamate hydrolase
F9Y86_14015	ENOG4105CI2	imidazolone-5-propionate hydrolase
F9Y86_14020	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
F9Y86_14030	ENOG4105DF5	DNA topoisomerase IV, subunit A
F9Y86_14035	ENOG4105D64	Mechanosensitive ion channel
F9Y86_14050	ENOG4105CK2	sodium dicarboxylate symporter
F9Y86_14055	ENOG4105KHC	sulfurtransferase
F9Y86_14075	ENOG4105C4R	Atp-dependent dna helicase
F9Y86_14085	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F9Y86_14095	ENOG4105DUM	transcriptional regulator, lysR family
F9Y86_14100	ENOG4105EMU	Dehydrogenase
F9Y86_14105	ENOG4105C9Q	fumarate hydratase class II
F9Y86_14115	ENOG4105K70	DNA-binding protein
F9Y86_14120	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F9Y86_14125	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9Y86_14145	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F9Y86_14150	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F9Y86_14160	ENOG4105KVH	Transcriptional regulator
F9Y86_14165	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
F9Y86_14170	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F9Y86_14180	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F9Y86_14190	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F9Y86_14220	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F9Y86_14225	ENOG4105UYK	outer membrane protein a
F9Y86_14235	ENOG4105C8Y	Acetylornithine aminotransferase
F9Y86_14240	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F9Y86_14245	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F9Y86_14250	ENOG4105VG0	50S ribosomal protein l34
F9Y86_14255	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F9Y86_14260	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
F9Y86_14265	ENOG4108S4H	thioesterase Superfamily protein
F9Y86_14285	ENOG4108S3W	Anti-feci sigma factor, fecr
F9Y86_14290	ENOG4105EMN	RNA polymerase sigma factor
F9Y86_14300	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F9Y86_14305	ENOG4105CPF	Cell wall formation (By similarity)
F9Y86_14315	ENOG4105C34	Pseudouridine synthase
F9Y86_14320	ENOG4107RY6	amino acid
F9Y86_14350	ENOG4105CH7	arginosuccinase
F9Y86_14360	ENOG4107T6X	nag kinase
F9Y86_14365	ENOG4107REN	Carbamoyltransferase
F9Y86_14370	ENOG4105C8Y	Acetylornithine aminotransferase
F9Y86_14375	ENOG4105II7	pyrroline-5-carboxylate reductase
F9Y86_14380	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
F9Y86_14385	ENOG4105CDH	Citrulline--aspartate ligase
F9Y86_14395	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F9Y86_14400	ENOG4105C01	Dihydroxy-acid dehydratase
F9Y86_14405	ENOG4105C7K	acetolactate synthase
F9Y86_14415	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F9Y86_14420	ENOG4105C7B	Threonine dehydratase
F9Y86_14460	ENOG4105DY9	regulatoR
F9Y86_14505	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F9Y86_14510	ENOG4105EIP	mannose-6-phosphate isomerase
F9Y86_14545	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
F9Y86_14565	ENOG4105CDV	Ompa motb domain protein
F9Y86_14585	ENOG4105DN3	alpha-2-macroglobulin domain protein
F9Y86_14590	ENOG4108JQB	penicillin-binding protein 1C
F9Y86_14595	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
F9Y86_14600	ENOG4105C6E	dna polymerase iii
F9Y86_14605	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F9Y86_14625	ENOG4105EE5	Membrane protein terC
F9Y86_14635	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F9Y86_14640	ENOG4107QTF	adenylosuccinate lyase
F9Y86_14665	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F9Y86_14670	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F9Y86_14680	ENOG4107QIJ	Aconitate hydratase 2
F9Y86_14685	ENOG4108I0Z	Aconitate hydratase
F9Y86_14710	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F9Y86_14715	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
F9Y86_14720	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9Y86_14740	ENOG4105D6J	arsenicaL-resistance protein
F9Y86_14760	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
F9Y86_14765	ENOG4105C9A	Phoh family
F9Y86_14775	ENOG4107QWK	SAICAR synthetase
F9Y86_14785	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
F9Y86_14790	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F9Y86_14840	ENOG4105EYK	Phosphatidylglycerophosphatase B
F9Y86_14845	ENOG4105NQG	DoxX
F9Y86_14860	ENOG4105FTV	AraC Family Transcriptional Regulator
F9Y86_14870	ENOG410836F	Transposase
F9Y86_14885	ENOG4108RWN	rrna methyltransferase
F9Y86_14895	ENOG4105CD3	dihydroorotase
F9Y86_14975	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
F9Y86_14980	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
F9Y86_14985	ENOG4108YZT	Adenosylcobinamide kinase
F9Y86_14995	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F9Y86_15005	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
F9Y86_15010	ENOG4105C19	ABC transporter
F9Y86_15015	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F9Y86_15020	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F9Y86_15030	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F9Y86_15035	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9Y86_15050	ENOG4105C25	Primosomal protein n'
F9Y86_15075	ENOG410904N	short-chain dehydrogenase reductase
F9Y86_15080	ENOG4105DXN	mazG family
F9Y86_15090	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F9Y86_15095	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F9Y86_15105	ENOG4105C39	capsular polysaccharide phosphotransferase
F9Y86_15110	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F9Y86_15115	ENOG41061MV	Arylsulfatase
F9Y86_15120	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F9Y86_15125	ENOG4105BZ1	(ABC) transporter
F9Y86_15135	ENOG4105CKK	Glycosyl transferase, family 2
F9Y86_15150	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F9Y86_15165	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F9Y86_15180	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F9Y86_15195	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F9Y86_15200	ENOG4105C2X	Arabinose 5-phosphate isomerase
F9Y86_15205	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9Y86_15225	ENOG4105DCF	alanine dehydrogenase
F9Y86_15230	ENOG4105K8N	protein family UPF0079, ATPase
F9Y86_15235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9Y86_15240	ENOG4105DCI	Phosphohydrolase
F9Y86_15245	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9Y86_15255	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9Y86_15260	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)