locus-tag	class	description
BK011_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BK011_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BK011_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BK011_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BK011_00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BK011_00035	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BK011_00045	ENOG4105D01	(LipO)protein
BK011_00050	ENOG4105E0M	Sulfatase
BK011_00060	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BK011_00075	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BK011_00085	ENOG4105F3H	Histidine kinase
BK011_00090	ENOG4105K59	histidine triad (HIT) protein
BK011_00095	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
BK011_00105	ENOG4105DCI	Phosphohydrolase
BK011_00110	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
BK011_00115	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BK011_00120	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BK011_00125	ENOG4105K4W	Could be involved in septation (By similarity)
BK011_00135	ENOG4105UQX	Mate efflux family protein
BK011_00140	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BK011_00145	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BK011_00150	ENOG4108JA2	transcriptioN-repair coupling factor
BK011_00160	ENOG4105CGF	Aromatic amino acid aminotransferase
BK011_00165	ENOG4105C8B	TIGR00159 family
BK011_00175	ENOG4107XQK	5-formyltetrahydrofolate cyclo-ligase
BK011_00180	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BK011_00190	ENOG41083MR	nifu domain-containing protein
BK011_00195	ENOG4105EPR	degv family
BK011_00205	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BK011_00210	ENOG4107QYV	phosphohexose isomerase
BK011_00215	ENOG4105K8N	protein family UPF0079, ATPase
BK011_00220	ENOG41072GX	Peptidase M22 Glycoprotease
BK011_00225	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
BK011_00230	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BK011_00270	ENOG4105C4R	Atp-dependent dna helicase
BK011_00280	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BK011_00285	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BK011_00295	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BK011_00310	ENOG4105C3M	thioredoxin reductase
BK011_00315	ENOG4105CIE	May be required for sporulation (By similarity)
BK011_00320	ENOG41085IX	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BK011_00335	ENOG4105C5H	ABC transporter
BK011_00380	ENOG4105VXP	Protein of unknown function DUF86
BK011_00425	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BK011_00430	ENOG4105FQP	Beta-lactamase
BK011_00445	ENOG4105CPC	Aldo Keto reductase
BK011_00455	ENOG4105EMD	TRANSCRIPTIONal
BK011_00465	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
BK011_00470	ENOG4108HHA	Transketolase
BK011_00475	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BK011_00485	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BK011_00510	ENOG4105C9K	Endothelin-converting enzyme 1
BK011_00515	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BK011_00525	ENOG4105C72	UPF0176 protein
BK011_00535	ENOG410836F	Transposase
BK011_00555	ENOG4108Z0Z	intracellular protease Pfpi family
BK011_00605	ENOG4107Y80	Major Facilitator superfamily
BK011_00615	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BK011_00620	ENOG4105YA8	Transcriptional regulator
BK011_00630	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
BK011_00635	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
BK011_00640	ENOG4105FRY	Dehydrogenase
BK011_00655	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
BK011_00660	ENOG4107CHF	5,6-aminomutase beta subunit
BK011_00665	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BK011_00670	ENOG4105UQX	Mate efflux family protein
BK011_00680	ENOG4105CI2	imidazolone-5-propionate hydrolase
BK011_00685	ENOG4105CCS	Glutamate formiminotransferase
BK011_00690	ENOG4105CGP	Urocanate hydratase
BK011_00695	ENOG4105C84	Histidine ammonia-lyase
BK011_00705	ENOG4107GFK	fumarate
BK011_00710	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
BK011_00715	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
BK011_00720	ENOG4105CHY	citrate lyase, alpha
BK011_00725	ENOG4105CI0	Citrate lyase
BK011_00730	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
BK011_00750	ENOG4107YT1	Glutamate mutase subunit sigma
BK011_00760	ENOG41082I2	s4 domain protein
BK011_00765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BK011_00770	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BK011_00775	ENOG4107XRM	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BK011_00780	ENOG4108Z03	MAF-like protein
BK011_00785	ENOG4105CG3	alpha amylase, catalytic region
BK011_00790	ENOG4105DME	alpha-galactosidase
BK011_00800	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BK011_00810	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BK011_00815	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BK011_00820	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BK011_00825	ENOG4105C6N	Formate acetyltransferase
BK011_00830	ENOG4105F1A	Pyruvate formate-lyase
BK011_00835	ENOG4105CKU	formyltetrahydrofolate synthetase
BK011_00840	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BK011_00845	ENOG4105F0N	pyrophosphate phospho-hydrolase
BK011_00850	ENOG4105CDY	transcriptional regulatory protein
BK011_00855	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BK011_00860	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
BK011_00865	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BK011_00880	ENOG4105DZB	Electron transport complex
BK011_00885	ENOG4105DGN	Electron transport complex
BK011_00895	ENOG4108R3D	Electron transport complex
BK011_00915	ENOG41082EV	50s ribosomal protein l31
BK011_00920	ENOG4107104	thymidine kinase
BK011_00925	ENOG4108Z6B	deaminase
BK011_00945	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BK011_00950	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BK011_00955	ENOG4107QJE	Chromosome Partitioning Protein
BK011_00960	ENOG4105FA0	parb-like partition protein
BK011_01055	ENOG410607W	Transposase
BK011_01060	ENOG4105EPR	degv family
BK011_01070	ENOG4105DKQ	ROK family
BK011_01080	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BK011_01085	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BK011_01090	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BK011_01095	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BK011_01100	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BK011_01105	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BK011_01110	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BK011_01120	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BK011_01125	ENOG41082SA	50s ribosomal protein l29
BK011_01130	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BK011_01135	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BK011_01140	ENOG41080DU	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BK011_01145	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BK011_01150	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BK011_01155	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BK011_01160	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BK011_01165	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BK011_01170	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BK011_01175	ENOG41087RB	50S ribosomal protein L30
BK011_01180	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BK011_01185	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BK011_01190	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BK011_01195	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BK011_01200	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BK011_01210	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BK011_01215	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BK011_01220	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BK011_01225	ENOG4108ZT0	50S ribosomal protein l17
BK011_01230	ENOG4108K8S	endonuclease I
BK011_01235	ENOG4105CPC	Aldo Keto reductase
BK011_01265	ENOG4105CBX	hi0933 family
BK011_01270	ENOG4105C3M	thioredoxin reductase
BK011_01275	ENOG4105K63	Thioredoxin
BK011_01280	ENOG4108JJB	ABC transporter
BK011_01285	ENOG4108JJB	ABC transporter
BK011_01290	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BK011_01295	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BK011_01300	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BK011_01305	ENOG4105FA2	dna polymerase iii
BK011_01310	ENOG4105MA4	psp1 domain protein
BK011_01315	ENOG41060K3	Methyltransferase
BK011_01325	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BK011_01335	ENOG4107AYK	membrAne
BK011_01340	ENOG4105DM4	PTS System
BK011_01345	ENOG4105DM4	PTS System
BK011_01350	ENOG4105DM4	PTS System
BK011_01360	ENOG410607W	Transposase
BK011_01365	ENOG4105C7N	Xanthine uracil vitamin C permease
BK011_01370	ENOG4107QHQ	amino acid
BK011_01380	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BK011_01385	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BK011_01405	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BK011_01420	ENOG4105C8N	cysteinyl-tRNA synthetase
BK011_01425	ENOG4108496	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BK011_01430	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BK011_01435	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BK011_01450	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BK011_01465	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BK011_01470	ENOG4107ZXU	DSBA oxidoreductase
BK011_01480	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BK011_01485	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BK011_01490	ENOG4107URM	50S ribosomal protein l10
BK011_01495	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BK011_01500	ENOG4107Y49	methyltransferase
BK011_01505	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BK011_01510	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BK011_01515	ENOG410836F	Transposase
BK011_01520	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BK011_01525	ENOG4105E1F	short-chain dehydrogenase reductase
BK011_01550	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BK011_01555	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BK011_01560	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BK011_01565	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BK011_01575	ENOG410607W	Transposase
BK011_01585	ENOG4105F8V	Hydrolase, tatD family
BK011_01590	ENOG4105C0H	protease
BK011_01595	ENOG4105CEV	competence damage-inducible protein
BK011_01600	ENOG41085KQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
BK011_01605	ENOG4108UUM	single-stranded DNA-binding protein
BK011_01610	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BK011_01630	ENOG4105BZR	domain protein
BK011_01635	ENOG4105CDU	Replicative dna helicase
BK011_01670	ENOG410607W	Transposase
BK011_01710	ENOG4105C59	p-type ATPase
BK011_01715	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BK011_01745	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BK011_01770	ENOG410836F	Transposase
BK011_01805	ENOG4108RMU	ferritin dps family protein
BK011_01810	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BK011_01815	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BK011_01820	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BK011_01825	ENOG4105CI3	gtp-binding protein typa
BK011_01830	ENOG4108YZG	isomerase
BK011_01835	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BK011_01855	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BK011_01870	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BK011_01875	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BK011_01880	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BK011_01885	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BK011_01895	ENOG4105F9F	transposase
BK011_01900	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BK011_01905	ENOG4105K46	50S ribosomal protein l27
BK011_01915	ENOG4107Y7S	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BK011_01930	ENOG4105W5Q	DNA repair protein (RadC
BK011_01935	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BK011_01940	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BK011_01945	ENOG4108Z9I	-acetyltransferase
BK011_01950	ENOG4105CMR	udp-glucose 4-epimerase
BK011_01955	ENOG4105EPR	degv family
BK011_01960	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BK011_01965	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BK011_01970	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BK011_02010	ENOG4105VMP	Transcriptional regulator
BK011_02020	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BK011_02035	ENOG4107YJ4	chain length determinant protein
BK011_02045	ENOG4105DPN	Oligoendopeptidase f
BK011_02050	ENOG4105C5F	glutamine synthetase
BK011_02065	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BK011_02070	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BK011_02075	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BK011_02080	ENOG4108IJ7	Glycine betaine
BK011_02125	ENOG4105ECY	inositol monophosphatase
BK011_02155	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
BK011_02165	ENOG4105EHG	Permease protein
BK011_02170	ENOG4105E0A	ABC, transporter
BK011_02185	ENOG4105WH1	Two component transcriptional regulator luxr family
BK011_02190	ENOG4108ZGX	Histidine kinase
BK011_02205	ENOG4105CJ1	ABC, transporter
BK011_02210	ENOG4105EQR	Transposase IS116 IS110 IS902
BK011_02215	ENOG4105E1F	short-chain dehydrogenase reductase
BK011_02220	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BK011_02245	ENOG4105DRS	transport system, permease
BK011_02250	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BK011_02260	ENOG4105CG3	alpha amylase, catalytic region
BK011_02265	ENOG4105ETE	Transcriptional regulator (LacI family
BK011_02285	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
BK011_02295	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BK011_02300	ENOG4105SKE	transcriptional Regulator LysR family
BK011_02315	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BK011_02320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BK011_02325	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BK011_02330	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BK011_02335	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BK011_02340	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BK011_02345	ENOG4107QQG	Dehydrogenase
BK011_02350	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BK011_02360	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BK011_02375	ENOG4107RXY	Glycosyl transferase
BK011_02395	ENOG4108UW5	maltose o-acetyltransferase
BK011_02410	ENOG4105D3Q	Sugar transferase
BK011_02415	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BK011_02425	ENOG4105DQ6	Transposase
BK011_02495	ENOG4108IJ9	(ABC) transporter
BK011_02500	ENOG4105EG2	ABC transporter, permease
BK011_02505	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BK011_02515	ENOG4105IRK	Glycosyl transferase (Group 1
BK011_02520	ENOG4107QW3	Sucrose phosphorylase
BK011_02530	ENOG4105DG6	mannose-6-phosphate isomerase
BK011_02555	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BK011_02565	ENOG4105DRS	transport system, permease
BK011_02580	ENOG4105FDP	GntR family transcriptional regulator
BK011_02590	ENOG4107QSA	Oxaloacetate decarboxylase
BK011_02605	ENOG4105D9Q	decarboxylase (Beta subunit)
BK011_02610	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BK011_02635	ENOG4108YYD	acetyltransferase
BK011_02655	ENOG410836F	Transposase
BK011_02660	ENOG4105VZ8	Transcriptional regulator
BK011_02740	ENOG4105DA5	(ABC) transporter
BK011_02785	ENOG4105FDP	GntR family transcriptional regulator
BK011_02800	ENOG4107YJ4	chain length determinant protein
BK011_02805	ENOG4105HTX	biosynthesis protein
BK011_02845	ENOG4105CJZ	response regulator
BK011_02850	ENOG4105BZW	Glycerate kinase
BK011_02855	ENOG4105DIH	basic membrane
BK011_02860	ENOG4108JQ9	ABC transporter
BK011_02865	ENOG4105UIB	(ABC) transporter
BK011_02885	ENOG4108UW5	maltose o-acetyltransferase
BK011_02900	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BK011_02905	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BK011_02910	ENOG4108UT2	hemolysin iii
BK011_02915	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BK011_02920	ENOG4105DAP	Nicotinate phosphoribosyltransferase
BK011_02925	ENOG4105D1Q	UPF0246 protein
BK011_02930	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BK011_02960	ENOG4105RKW	reductase (By
BK011_02975	ENOG4105C75	arginyL-tRNA synthetase
BK011_02985	ENOG4105C83	adenylosuccinate lyase
BK011_02990	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BK011_02995	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BK011_03000	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BK011_03010	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BK011_03015	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BK011_03020	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BK011_03025	ENOG4105DX0	Hemolysin A
BK011_03030	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BK011_03035	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BK011_03040	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BK011_03185	ENOG4105BZU	Histidine kinase
BK011_03190	ENOG4105BZU	Histidine kinase
BK011_03195	ENOG4105BZU	Histidine kinase
BK011_03200	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
BK011_03210	ENOG4107SVH	Potassium channel protein
BK011_03240	ENOG410836F	Transposase
BK011_03250	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BK011_03260	ENOG4105BZU	Histidine kinase
BK011_03265	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BK011_03270	ENOG4105CPQ	Dehydrogenase
BK011_03275	ENOG4108YZ4	nudix hydrolase
BK011_03285	ENOG4105C26	Dehydrogenase
BK011_03300	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BK011_03315	ENOG4105BZ8	glutamate synthase
BK011_03320	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
BK011_03330	ENOG410607W	Transposase
BK011_03345	ENOG4105KVH	Transcriptional regulator
BK011_03350	ENOG4105UQX	Mate efflux family protein
BK011_03365	ENOG4108U5N	UPF0316 protein
BK011_03385	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
BK011_03390	ENOG4105C1A	potassium transporter peripheral membrane
BK011_03420	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BK011_03425	ENOG4105CHR	reductase
BK011_03435	ENOG4105EA8	2-Nitropropane dioxygenase
BK011_03440	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BK011_03450	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BK011_03455	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BK011_03460	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BK011_03465	ENOG4105C5I	Dehydrogenase
BK011_03480	ENOG4107XCH	Cyclase family
BK011_03485	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BK011_03500	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BK011_03530	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BK011_03540	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BK011_03545	ENOG4107QJZ	Glycosyl transferase, family 2
BK011_03550	ENOG4105BZU	Histidine kinase
BK011_03560	ENOG4107Y7Q	pfkb domain protein
BK011_03595	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BK011_03610	ENOG4105DPN	Oligoendopeptidase f
BK011_03615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BK011_03625	ENOG4105C5H	ABC transporter
BK011_03645	ENOG4105C59	p-type ATPase
BK011_03655	ENOG410646M	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BK011_03715	ENOG4105K56	Transcriptional regulator
BK011_03720	ENOG4108V06	Glutathione peroxidase
BK011_03750	ENOG4105C1J	atp-dependent rna helicase
BK011_03760	ENOG4105EFZ	amidohydrolase
BK011_03765	ENOG410902V	Modulates RecA activity (By similarity)
BK011_03780	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BK011_03785	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BK011_03800	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BK011_03820	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BK011_03825	ENOG4105C25	Primosomal protein n'
BK011_03835	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BK011_03845	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BK011_03850	ENOG4105CHV	Transcription elongation factor NusA
BK011_03855	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BK011_03865	ENOG4105FDK	ABC transporter
BK011_03895	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BK011_03905	ENOG4105CN5	Metallo-Beta-Lactamase
BK011_03915	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BK011_03920	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BK011_03925	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BK011_03930	ENOG4105F23	Fibronectin-binding protein
BK011_03950	ENOG4108IUW	ABC transporter
BK011_03965	ENOG4105MS2	ribosomal subunit Interface protein
BK011_03975	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BK011_03980	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BK011_03985	ENOG41067QW	Transcriptional regulator
BK011_03990	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BK011_03995	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
BK011_04000	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
BK011_04035	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
BK011_04045	ENOG4105QNR	S1 RNA binding domain protein
BK011_04060	ENOG4105E5Q	amino acid AbC transporter
BK011_04065	ENOG4108HW3	(ABC) transporter
BK011_04070	ENOG4105VEQ	Cold shock protein
BK011_04075	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BK011_04080	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BK011_04085	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BK011_04090	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BK011_04095	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BK011_04110	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BK011_04115	ENOG4105D48	metallophosphoesterase
BK011_04120	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BK011_04130	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BK011_04135	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BK011_04155	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BK011_04160	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BK011_04170	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BK011_04175	ENOG4105TQK	DNA polymerase iii, delta' subunit
BK011_04190	ENOG4108D32	Methyltransferase
BK011_04205	ENOG4105CE1	Ferrous iron transport protein b
BK011_04210	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
BK011_04215	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BK011_04225	ENOG4105CFP	Peptidase U32
BK011_04235	ENOG4108VQJ	O-methyltransferase
BK011_04240	ENOG4105VPH	UPF0473 protein
BK011_04245	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BK011_04250	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BK011_04260	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
BK011_04265	ENOG4105D78	K07001 NTE family protein
BK011_04270	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BK011_04275	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BK011_04290	ENOG4108SAX	Membrane
BK011_04300	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BK011_04305	ENOG4105E4P	ATPase (AAA
BK011_04315	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BK011_04320	ENOG4105E5G	Alpha beta hydrolase fold
BK011_04330	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BK011_04335	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BK011_04340	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BK011_04345	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BK011_04350	ENOG4105D1F	ATP-binding protein
BK011_04360	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BK011_04385	ENOG4108IUX	(ABC) transporter
BK011_04390	ENOG4105C22	threonyL-tRNA synthetase
BK011_04410	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BK011_04415	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BK011_04430	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
BK011_04435	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BK011_04440	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BK011_04445	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BK011_04455	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BK011_04460	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BK011_04490	ENOG4106A3R	peptidase
BK011_04495	ENOG4105X0D	Fimbrial protein
BK011_04500	ENOG4105D7Q	type ii secretion system
BK011_04505	ENOG4107QHF	type ii secretion system protein e
BK011_04530	ENOG4108KP7	hydrolase
BK011_04540	ENOG410607W	Transposase
BK011_04565	ENOG4108C33	Resolvase
BK011_04585	ENOG410607W	Transposase
BK011_04610	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BK011_04615	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BK011_04620	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BK011_04630	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BK011_04635	ENOG4105KG3	cytidine deaminase
BK011_04640	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BK011_04645	ENOG4105C9A	Phoh family
BK011_04660	ENOG4105XZU	Preprotein translocase, subunit SecG
BK011_04665	ENOG4105D7W	serine acetyltransferase
BK011_04670	ENOG4105C6T	cysteine synthase
BK011_04685	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BK011_04690	ENOG4105EJQ	L-serine dehydratase
BK011_04695	ENOG4105CTD	carboxy-peptidase
BK011_04705	ENOG4105CJW	magnesium transporter
BK011_04710	ENOG4105CJW	magnesium transporter
BK011_04715	ENOG4105KST	dependent repressor
BK011_04725	ENOG4105D9R	oxidoreductase
BK011_04735	ENOG4105BZ1	(ABC) transporter
BK011_04740	ENOG4105BZ1	(ABC) transporter
BK011_04760	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BK011_04775	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BK011_04780	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BK011_04790	ENOG410607W	Transposase
BK011_04800	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BK011_04810	ENOG4105CTQ	phosphohexokinase
BK011_04825	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BK011_04855	ENOG4105C0B	DNA polymerase III (alpha subunit)
BK011_04860	ENOG4108Z29	Flavodoxin
BK011_04870	ENOG4105BZ1	(ABC) transporter
BK011_04875	ENOG4105BZ1	(ABC) transporter
BK011_04885	ENOG4105CSM	endonuclease III
BK011_04895	ENOG4107SU0	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BK011_04900	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BK011_04905	ENOG4105CB5	ATP-dependent DNA helicase recG
BK011_04910	ENOG4105C59	p-type ATPase
BK011_04920	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BK011_04925	ENOG4105E2X	shikimate dehydrogenase
BK011_04930	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
BK011_04935	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BK011_04940	ENOG4105D49	3-dehydroquinate synthase
BK011_04950	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
BK011_04965	ENOG4105EPR	degv family
BK011_04970	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BK011_04995	ENOG4105HC0	Na H antiporter
BK011_05000	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BK011_05005	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BK011_05010	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BK011_05015	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BK011_05020	ENOG4105Q2H	domain protein
BK011_05030	ENOG4105EQI	Metal Dependent Phosphohydrolase
BK011_05045	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BK011_05050	ENOG4105F9F	transposase
BK011_05060	ENOG410852I	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BK011_05065	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BK011_05085	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BK011_05110	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BK011_05120	ENOG4107RAQ	aminopeptidase
BK011_05135	ENOG4108IUX	(ABC) transporter
BK011_05150	ENOG41086CC	50s ribosomal protein L35
BK011_05155	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BK011_05165	ENOG4105CN9	Peptidase m42 family protein
BK011_05170	ENOG4106H78	methyltransferase
BK011_05180	ENOG4105VXM	UPF0154 protein
BK011_05185	ENOG4107Y8I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BK011_05190	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BK011_05195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BK011_05200	ENOG4105C22	threonyL-tRNA synthetase
BK011_05210	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BK011_05225	ENOG4108Z7G	MaoC domain protein dehydratase
BK011_05230	ENOG4105C1G	acyl-Coa dehydrogenase
BK011_05235	ENOG4105BZJ	Electron transfer flavoprotein
BK011_05250	ENOG4105CHR	reductase
BK011_05270	ENOG4105C0Z	ABC transporter
BK011_05275	ENOG4108IV0	ABC, transporter
BK011_05285	ENOG4105CYC	Transferase
BK011_05295	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BK011_05300	ENOG4107RB3	L-asparaginase
BK011_05310	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BK011_05315	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BK011_05320	ENOG4105CSA	Coproporphyrinogen iii oxidase
BK011_05325	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BK011_05335	ENOG4108JU6	CBS domain protein
BK011_05340	ENOG4105C37	(CBS) domain
BK011_05365	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BK011_05380	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BK011_05395	ENOG4108EKI	Dehydrogenase
BK011_05405	ENOG4105BZU	Histidine kinase
BK011_05430	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BK011_05435	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BK011_05440	ENOG4105DTN	riboflavin biosynthesis protein ribF
BK011_05445	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BK011_05465	ENOG4105K63	Thioredoxin
BK011_05470	ENOG4105C98	muts2 protein
BK011_05475	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BK011_05480	ENOG4105C34	Pseudouridine synthase
BK011_05485	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BK011_05505	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BK011_05510	ENOG4105C9M	aspartyl-trna synthetase
BK011_05515	ENOG4107R36	histidyl-tRNA synthetase
BK011_05520	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BK011_05530	ENOG4105DBI	uridine monophosphokinase
BK011_05535	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BK011_05540	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BK011_05545	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BK011_05550	ENOG4105D1H	recombination factor protein RarA
BK011_05560	ENOG4105DBV	ornithine carbamoyltransferase
BK011_05565	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BK011_05570	ENOG4106M28	alanine racemase domain protein
BK011_05580	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
BK011_05585	ENOG4105KIJ	D-ornithine aminomutase S component
BK011_05600	ENOG4108KR4	dihydrodipicolinate reductase
BK011_05605	ENOG4108WBT	adenosyltransferase
BK011_05610	ENOG4105CN5	Metallo-Beta-Lactamase
BK011_05655	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BK011_05660	ENOG4105E9Q	Acyl-transferase
BK011_05665	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BK011_05670	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BK011_05675	ENOG4107QSE	Dipeptidase
BK011_05700	ENOG4108UUM	single-stranded DNA-binding protein
BK011_05720	ENOG4107TH2	purine nucleoside phosphorylase
BK011_05725	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BK011_05740	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BK011_05745	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BK011_05750	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BK011_05755	ENOG4105DFA	alanine racemase domain protein
BK011_05760	ENOG4105C3G	gtp-binding protein
BK011_05765	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BK011_05770	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BK011_05780	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BK011_05785	ENOG4105CEN	a g-specific adenine glycosylase
BK011_05795	ENOG4108TVJ	Nitroreductase
BK011_05805	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BK011_05810	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BK011_05855	ENOG4105FE9	pseudouridine synthase
BK011_05880	ENOG41090MY	MarR family Transcriptional regulator
BK011_05885	ENOG4105FBA	Phospholipase Carboxylesterase
BK011_05905	ENOG4105K7K	Transcriptional regulator
BK011_05915	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BK011_05920	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BK011_05925	ENOG4108YBP	pseudouridine synthase
BK011_05945	ENOG4105D82	Glutamate dehydrogenase
BK011_05950	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BK011_05970	ENOG4105SX7	Transporter
BK011_05995	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BK011_06000	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BK011_06015	ENOG4105BZ1	(ABC) transporter
BK011_06025	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
BK011_06045	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BK011_06095	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
BK011_06100	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
BK011_06115	ENOG4105FBA	Phospholipase Carboxylesterase
BK011_06145	ENOG4108RAV	Conserved protein
BK011_06170	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BK011_06175	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BK011_06185	ENOG4105C7H	Helicase, RecD TraA family
BK011_06190	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BK011_06200	ENOG4108521	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BK011_06210	ENOG4108Z5K	methylglyoxal synthase
BK011_06215	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BK011_06220	ENOG41086GB	50S ribosomal protein L32
BK011_06235	ENOG4105DF9	Lipoate-protein, ligase
BK011_06245	ENOG4105DP4	dak2 domain fusion protein ylov
BK011_06250	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BK011_06255	ENOG4105CFG	Acts as a chaperone (By similarity)
BK011_06260	ENOG41082SB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BK011_06265	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BK011_06270	ENOG4105C5X	domain protein
BK011_06275	ENOG41084ED	50S ribosomal protein L33
BK011_06280	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BK011_06295	ENOG4105C59	p-type ATPase
BK011_06305	ENOG4105C5H	ABC transporter
BK011_06360	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BK011_06365	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BK011_06380	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BK011_06410	ENOG4105ETE	Transcriptional regulator (LacI family
BK011_06460	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BK011_06465	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BK011_06470	ENOG410607W	Transposase
BK011_06480	ENOG4107QI6	Cysteine desulfurase
BK011_06510	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BK011_06535	ENOG4108KN0	Choline kinase
BK011_06545	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BK011_06550	ENOG4108TYN	CAAX amino terminal protease family protein
BK011_06560	ENOG4105K70	DNA-binding protein
BK011_06565	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BK011_06570	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BK011_06575	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BK011_06580	ENOG4105CAT	Cytidine monophosphate kinase
BK011_06585	ENOG4105FE9	pseudouridine synthase
BK011_06590	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BK011_06595	ENOG4105BZ1	(ABC) transporter
BK011_06610	ENOG4108K8S	endonuclease I
BK011_06925	ENOG4105RHY	Pfam:UPF0157
BK011_06955	ENOG4105RHY	Pfam:UPF0157
BK011_06990	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BK011_07020	ENOG4105C0H	protease
BK011_07080	ENOG4107V8I	Glycosyl transferases group 1
BK011_07095	ENOG4105EPR	degv family
BK011_07110	ENOG4105CIG	ABC transporter
BK011_07115	ENOG4105CIG	ABC transporter
BK011_07200	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BK011_07255	ENOG4105DQ6	Transposase
BK011_07270	ENOG4105DP4	dak2 domain fusion protein ylov
BK011_07275	ENOG410858W	50S ribosomal protein l28
BK011_07285	ENOG4105DJV	ribulose-phosphate 3-epimerase
BK011_07290	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BK011_07295	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BK011_07305	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BK011_07310	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BK011_07320	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BK011_07330	ENOG4105N5T	Radical SAM Protein
BK011_07340	ENOG4105WJF	
BK011_07355	ENOG4105C8T	Leucyl-tRNA synthetase
BK011_07360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BK011_07370	ENOG4105EAD	ABC transporter
BK011_07380	ENOG4108IUJ	4-alpha-glucanotransferase
BK011_07385	ENOG4105CG3	alpha amylase, catalytic region
BK011_07395	ENOG4105ETE	Transcriptional regulator (LacI family
BK011_07405	ENOG4108IUM	Glycogen debranching enzyme
BK011_07410	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BK011_07420	ENOG4105EG2	ABC transporter, permease
BK011_07430	ENOG4107FKK	extracellular solute-binding protein family 1
BK011_07440	ENOG4108IUM	Glycogen debranching enzyme
BK011_07450	ENOG4105D7N	magnesium and cobalt transport protein CorA
BK011_07470	ENOG4107QIZ	NADH dehydrogenase
BK011_07505	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
BK011_07515	ENOG4105CG3	alpha amylase, catalytic region
BK011_07530	ENOG4105CAH	Chromate
BK011_07540	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BK011_07555	ENOG4105CJQ	hydrolase, family 31
BK011_07580	ENOG4107RDP	Dehydrogenase
BK011_07595	ENOG4105E0X	reductase
BK011_07600	ENOG4105BZU	Histidine kinase
BK011_07605	ENOG4108W5N	phosphatidylglycerophosphatase a
BK011_07620	ENOG4105F9F	transposase
BK011_07625	ENOG4105PDP	Short chain dehydrogenase
BK011_07630	ENOG4105CEU	Arginine dihydrolase
BK011_07640	ENOG4108UQV	Membrane
BK011_07645	ENOG4105CPC	Aldo Keto reductase
BK011_07675	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BK011_07685	ENOG4105D6J	arsenicaL-resistance protein
BK011_07695	ENOG410836F	Transposase
BK011_07705	ENOG4107S21	permease
BK011_07715	ENOG4105BZU	Histidine kinase
BK011_07740	ENOG41067QW	Transcriptional regulator
BK011_07830	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BK011_07880	ENOG4105CPC	Aldo Keto reductase
BK011_07890	ENOG4105KJF	protein tyrosine phosphatase
BK011_07910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BK011_07920	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BK011_07930	ENOG4105BZU	Histidine kinase
BK011_07940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BK011_07965	ENOG4105CFP	Peptidase U32
BK011_08000	ENOG41067QW	Transcriptional regulator
BK011_08085	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BK011_08090	ENOG4105DBI	uridine monophosphokinase
BK011_08100	ENOG4105C59	p-type ATPase
BK011_08105	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BK011_08140	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BK011_08145	ENOG4105KNE	Phosphatidate cytidylyltransferase
BK011_08150	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BK011_08155	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BK011_08160	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BK011_08165	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BK011_08170	ENOG4105CE9	30S ribosomal protein S2
BK011_08175	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BK011_08185	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BK011_08190	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BK011_08200	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BK011_08255	ENOG4105MIX	Adenylate cyclase
BK011_08265	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
BK011_08270	ENOG4105DPN	Oligoendopeptidase f
BK011_08275	ENOG4105C31	Tryptophanyl-tRNA synthetase
BK011_08285	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BK011_08295	ENOG4105ETE	Transcriptional regulator (LacI family
BK011_08300	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BK011_08305	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BK011_08310	ENOG41080SB	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BK011_08315	ENOG4105VB6	UPF0109 protein
BK011_08320	ENOG4105K5M	30s ribosomal protein S16
BK011_08335	ENOG4105I08	Pseudouridine synthase
BK011_08340	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BK011_08350	ENOG4108RWN	rrna methyltransferase
BK011_08365	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BK011_08370	ENOG4105CP7	Triose-phosphate isomerase
BK011_08385	ENOG4105BZA	Phosphoglycerate kinase
BK011_08420	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BK011_08425	ENOG410836F	Transposase
BK011_08435	ENOG4105JRK	feS assembly protein SufD
BK011_08440	ENOG4105C3K	feS assembly ATPase SufC
BK011_08465	ENOG4108JQ7	(ABC) transporter
BK011_08465	ENOG4108JQ7	(ABC) transporter
BK011_08475	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BK011_08485	ENOG4107QSI	ABC, transporter
BK011_08495	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BK011_08500	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BK011_08540	ENOG4105BZU	Histidine kinase
BK011_08550	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BK011_08555	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BK011_08560	ENOG4105E2Z	phosphate ABC transporter (Permease
BK011_08565	ENOG4105C8U	phosphate abc transporter
BK011_08595	ENOG4108K0B	C-di-gmp phosphodiesterase
BK011_08605	ENOG4105CJ1	ABC, transporter
BK011_08645	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BK011_08655	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
BK011_08660	ENOG4105EPR	degv family
BK011_08665	ENOG4105F22	Major Facilitator Superfamily
BK011_08675	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BK011_08680	ENOG4108JQ1	Dehydrogenase
BK011_08715	ENOG4105DB4	
BK011_08745	ENOG4105CGK	Exodeoxyribonuclease III
BK011_08775	ENOG4105C1J	atp-dependent rna helicase
BK011_08815	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BK011_08820	ENOG4105FQP	Beta-lactamase
BK011_08845	ENOG4105CIG	ABC transporter
BK011_08865	ENOG41062D9	Histidine kinase
BK011_08870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BK011_08895	ENOG41067QW	Transcriptional regulator
BK011_08915	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
BK011_08930	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BK011_08960	ENOG410646M	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BK011_08965	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BK011_08985	ENOG4105M6F	mutator MutT protein
BK011_08990	ENOG4105CFI	type iii restriction protein res subunit
BK011_09025	ENOG4108DQE	riboflavin reductase
BK011_09035	ENOG4105E3Q	saccharopine dehydrogenase
BK011_09045	ENOG4105CFH	Aspartokinase
BK011_09050	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BK011_09070	ENOG4105BZU	Histidine kinase
BK011_09090	ENOG4108IUW	ABC transporter
BK011_09105	ENOG4105EQR	Transposase IS116 IS110 IS902
BK011_09120	ENOG4105EXU	Membrane
BK011_09130	ENOG4105DVE	abc transporter atp-binding protein
BK011_09140	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BK011_09150	ENOG4107Y70	Heat shock protein
BK011_09160	ENOG4107URF	beta-phospho-glucomutase
BK011_09165	ENOG4107QW3	Sucrose phosphorylase
BK011_09185	ENOG4105ETE	Transcriptional regulator (LacI family
BK011_09195	ENOG4105EQR	Transposase IS116 IS110 IS902
BK011_09215	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BK011_09220	ENOG4108RS6	transposase
BK011_09230	ENOG4108X79	transcriptional regulator
BK011_09235	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BK011_09240	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BK011_09245	ENOG4107SG5	Dehydrogenase
BK011_09255	ENOG4108YZG	isomerase
BK011_09260	ENOG4108IUS	Transketolase
BK011_09280	ENOG4105DRS	transport system, permease
BK011_09290	ENOG4105CJQ	hydrolase, family 31
BK011_09305	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
BK011_09320	ENOG4107QX8	SPFH domain, Band 7 family protein
BK011_09330	ENOG410607W	Transposase
BK011_09355	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
BK011_09360	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BK011_09370	ENOG4105I1K	ABC transporter
BK011_09385	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BK011_09410	ENOG4105CBG	Sulfatase
BK011_09425	ENOG4105CG3	alpha amylase, catalytic region
BK011_09460	ENOG4105C4X	radical SAM domain protein
BK011_09465	ENOG4108K4B	hydrolase
BK011_09475	ENOG4105CP2	von willebrand factor, type a
BK011_09480	ENOG4105DQ6	Transposase
BK011_09535	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
BK011_09540	ENOG4108IJ6	ABC transporter
BK011_09550	ENOG410667J	hydrolase
BK011_09555	ENOG4108UH6	UPF0754 membrane protein
BK011_09575	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
BK011_09580	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BK011_09585	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BK011_09590	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BK011_09595	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BK011_09600	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BK011_09605	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BK011_09610	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BK011_09615	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BK011_09620	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
BK011_09640	ENOG4105EG2	ABC transporter, permease
BK011_09650	ENOG4105ETE	Transcriptional regulator (LacI family
BK011_09680	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BK011_09685	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BK011_09695	ENOG4108JQ7	(ABC) transporter
BK011_09700	ENOG4107QSI	ABC, transporter
BK011_09720	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BK011_09760	ENOG4106AKJ	
BK011_09770	ENOG4105CBD	Diacylglycerol kinase
BK011_09785	ENOG410607W	Transposase
BK011_09795	ENOG4105CHU	acetyl-coa acetyltransferase
BK011_09800	ENOG4105CRW	Short chain fatty acid transporter
BK011_09810	ENOG4107QP7	CoA-transferase subunit A
BK011_09815	ENOG4105MKU	Transcriptional regulator
BK011_09830	ENOG4105DQ6	Transposase
BK011_09840	ENOG4107QN2	dihydrolipoyl dehydrogenase
BK011_09845	ENOG4105C7S	Dehydrogenase
BK011_09850	ENOG4105CPP	Dehydrogenase, E1 component
BK011_09855	ENOG4107RUY	(E1 component), alpha subunit
BK011_09860	ENOG4105E4P	ATPase (AAA
BK011_09865	ENOG4105EQR	Transposase IS116 IS110 IS902
BK011_09870	ENOG4105CYW	agmatinase
BK011_09875	ENOG4105CXN	decarboxylase
BK011_09880	ENOG4105D8X	mechanosensitive ion channel
BK011_09885	ENOG41086D8	Transcriptional regulator
BK011_09905	ENOG4105BZU	Histidine kinase
BK011_09935	ENOG4105D5T	phosphonate abc transporter
BK011_09945	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
BK011_09950	ENOG4107RE7	phosphate butyryltransferase
BK011_09955	ENOG4105CKM	Branched-chain carboxylic acid kinase
BK011_09960	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
BK011_09965	ENOG4105C0F	tryptophanase EC 4.1.99.1
BK011_09985	ENOG4105C6T	cysteine synthase
BK011_10005	ENOG4105EAD	ABC transporter
BK011_10015	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
BK011_10020	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BK011_10025	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BK011_10035	ENOG4105D6A	Electron transport complex
BK011_10045	ENOG4105C26	Dehydrogenase
BK011_10050	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BK011_10075	ENOG4105C19	ABC transporter
BK011_10095	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BK011_10115	ENOG4105KME	endoribonuclease L-psp
BK011_10140	ENOG4105KGF	protein, YerC YecD
BK011_10145	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BK011_10170	ENOG4108M7F	enoyl-CoA hydratase isomerase
BK011_10175	ENOG4105BZU	Histidine kinase
BK011_10180	ENOG4105BZU	Histidine kinase
BK011_10200	ENOG4105RD7	BadF BadG BcrA BcrD
BK011_10205	ENOG4105D17	glycoside hydrolase, family 3 domain protein
BK011_10210	ENOG4105EHZ	conserved protein UCP016719
BK011_10220	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
BK011_10245	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BK011_10270	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
BK011_10275	ENOG4107QK9	Beta-lactamase
BK011_10280	ENOG4105F32	YngK protein
BK011_10285	ENOG4105F32	YngK protein
BK011_10290	ENOG4105F8D	glycoside hydrolase family 4
BK011_10305	ENOG4105CQB	FAD linked oxidase domain protein
BK011_10315	ENOG4105BZJ	Electron transfer flavoprotein
BK011_10340	ENOG4105CBX	hi0933 family
BK011_10370	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BK011_10375	ENOG4106CC8	Bacterial inner membrane protein
BK011_10395	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BK011_10400	ENOG4105C6E	dna polymerase iii
BK011_10405	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BK011_10410	ENOG4105KT7	mgtC SapB transporter
BK011_10415	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BK011_10420	ENOG4105SFS	phosphoesterase RecJ domain protein
BK011_10425	ENOG4105SFS	phosphoesterase RecJ domain protein
BK011_10460	ENOG4108IJ9	(ABC) transporter
BK011_10465	ENOG4105C5S	asparaginyl-tRNA synthetase
BK011_10470	ENOG4105CGY	Dna recombination protein
BK011_10485	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BK011_10490	ENOG4108585	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)