locus-tag	class	description
KHQ88_00010	COG0191	fructose-bisphosphate aldolase activity
KHQ88_00020	COG2610	gluconate transmembrane transporter activity
KHQ88_00025	COG1349	DNA-binding transcription factor activity
KHQ88_00030	COG3395	kinase activity
KHQ88_00035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KHQ88_00040	COG1098	S1 RNA binding domain
KHQ88_00055	COG0802	atpase or kinase
KHQ88_00060	COG1214	PFAM Peptidase M22, glycoprotease
KHQ88_00070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHQ88_00075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHQ88_00085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHQ88_00090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHQ88_00105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHQ88_00115	COG0736	holo-[acyl-carrier-protein] synthase activity
KHQ88_00125	COG2183	response to ionizing radiation
KHQ88_00170	COG0701	Predicted permease
KHQ88_00185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHQ88_00190	COG0187	DNA topoisomerase II activity
KHQ88_00205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHQ88_00210	COG4221	oxidoreductase activity
KHQ88_00220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHQ88_00230	COG1607	acyl-coa hydrolase
KHQ88_00235	COG3246	L-lysine catabolic process to acetate
KHQ88_00240	COG0604	alcohol dehydrogenase
KHQ88_00245	COG1509	lysine 2,3-aminomutase activity
KHQ88_00255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHQ88_00260	COG5012	cobalamin binding
KHQ88_00265	COG2096	Adenosyltransferase
KHQ88_00270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHQ88_00290	COG3052	prosthetic group binding
KHQ88_00300	COG3051	citrate lyase alpha subunit
KHQ88_00320	COG0534	Mate efflux family protein
KHQ88_00350	COG1269	ATP hydrolysis coupled proton transport
KHQ88_00380	COG1394	ATPase activity, coupled to movement of substances
KHQ88_00390	COG2153	protein acetylation
KHQ88_00415	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ88_00430	COG1307	EDD domain protein, DegV family
KHQ88_00460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KHQ88_00465	COG2356	endonuclease I
KHQ88_00470	COG1744	ABC transporter substrate-binding protein PnrA-like
KHQ88_00475	COG3845	ABC transporter
KHQ88_00480	COG4603	Belongs to the binding-protein-dependent transport system permease family
KHQ88_00485	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHQ88_00490	COG0827	DNA restriction-modification system
KHQ88_00495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHQ88_00515	COG0587	DNA-directed DNA polymerase activity
KHQ88_00525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHQ88_00550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ88_00560	COG0475	glutathione-regulated potassium exporter activity
KHQ88_00580	COG1461	Dihydroxyacetone kinase
KHQ88_00600	COG3033	Beta-eliminating lyase
KHQ88_00650	COG2033	superoxide reductase activity
KHQ88_00660	COG1968	undecaprenyl-diphosphatase activity
KHQ88_00670	COG0489	protein tyrosine kinase activity
KHQ88_00680	COG0745	RESPONSE REGULATOR receiver
KHQ88_00685	COG3850	Histidine kinase
KHQ88_00685	COG5002	protein histidine kinase activity
KHQ88_00695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ88_00715	COG0534	Mate efflux family protein
KHQ88_00720	COG1073	alpha beta
KHQ88_00740	COG0366	Alpha amylase catalytic
KHQ88_00745	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHQ88_00750	COG4974	Belongs to the 'phage' integrase family
KHQ88_00755	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHQ88_00805	COG2361	Protein of unknown function DUF86
KHQ88_00810	COG0656	L-ascorbic acid biosynthetic process
KHQ88_00840	COG3590	peptidase
KHQ88_00845	COG1957	nucleoside hydrolase
KHQ88_00865	COG1704	LemA family
KHQ88_00880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHQ88_00885	COG1126	abc transporter atp-binding protein
KHQ88_00900	COG3620	sequence-specific DNA binding
KHQ88_00905	COG0009	L-threonylcarbamoyladenylate synthase
KHQ88_00910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ88_00920	COG0488	(ABC) transporter
KHQ88_00940	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KHQ88_00950	COG1805	sodium ion transport
KHQ88_00955	COG0693	protein deglycase activity
KHQ88_01025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHQ88_01050	COG0628	permease
KHQ88_01070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHQ88_01080	COG0705	Rhomboid family
KHQ88_01080	COG0457	Tetratricopeptide repeat
KHQ88_01090	COG1929	Belongs to the glycerate kinase type-1 family
KHQ88_01115	COG2211	Major facilitator Superfamily
KHQ88_01120	COG1472	Belongs to the glycosyl hydrolase 3 family
KHQ88_01135	COG1362	aminopeptidase activity
KHQ88_01240	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHQ88_01285	COG0513	Belongs to the DEAD box helicase family
KHQ88_01300	COG2199	diguanylate cyclase activity
KHQ88_01300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KHQ88_01315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHQ88_01330	COG1278	Cold shock
KHQ88_01340	COG1803	Methylglyoxal synthase
KHQ88_01345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHQ88_01360	COG0436	Aminotransferase
KHQ88_01370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ88_01380	COG2217	Heavy metal translocating P-type atpase
KHQ88_01395	COG1309	transcriptional regulator
KHQ88_01410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KHQ88_01415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHQ88_01420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KHQ88_01425	COG1902	pentaerythritol trinitrate reductase activity
KHQ88_01430	COG0384	phenazine biosynthesis protein PhzF
KHQ88_01435	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ88_01450	COG1309	transcriptional regulator
KHQ88_01465	COG4946	Tricorn protease homolog
KHQ88_01465	COG1506	peptidase
KHQ88_01465	COG0823	Involved in the tonB-independent uptake of proteins
KHQ88_01480	COG1131	(ABC) transporter
KHQ88_01490	COG1217	gtp-binding protein TYPA
KHQ88_01500	COG1396	sequence-specific DNA binding
KHQ88_01520	COG2030	dehydratase
KHQ88_01525	COG1960	acyl-CoA dehydrogenase activity
KHQ88_01530	COG2086	electron transfer activity
KHQ88_01535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KHQ88_01540	COG2081	HI0933 family
KHQ88_01545	COG0583	DNA-binding transcription factor activity
KHQ88_01550	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHQ88_01560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KHQ88_01595	COG1760	l-serine dehydratase
KHQ88_01645	COG0504	CTP synthase activity
KHQ88_01665	COG1136	(ABC) transporter
KHQ88_01700	COG1937	Protein conserved in bacteria
KHQ88_01720	COG0432	Pfam Uncharacterised protein family UPF0047
KHQ88_01740	COG4487	mechanosensitive ion channel activity
KHQ88_01740	COG4487	mechanosensitive ion channel activity
KHQ88_01755	COG1194	a g-specific adenine glycosylase
KHQ88_01775	COG0346	lactoylglutathione lyase activity
KHQ88_01785	COG0400	carboxylic ester hydrolase activity
KHQ88_01795	COG1131	(ABC) transporter
KHQ88_01810	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHQ88_01835	COG2356	endonuclease I
KHQ88_01850	COG2309	aminopeptidase activity
KHQ88_01855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KHQ88_01860	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHQ88_01875	COG2746	aminoglycoside 3-N-acetyltransferase activity
KHQ88_01880	COG0405	Gamma-glutamyltransferase
KHQ88_01890	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHQ88_01910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHQ88_01915	COG0194	GDP metabolic process
KHQ88_01925	COG3118	belongs to the thioredoxin family
KHQ88_01930	COG0492	ferredoxin-NADP+ reductase activity
KHQ88_01945	COG1982	Orn Lys Arg decarboxylase major
KHQ88_01960	COG4656	Part of a membrane complex involved in electron transport
KHQ88_01985	COG4657	Part of a membrane complex involved in electron transport
KHQ88_02000	COG2986	histidine ammonia-lyase
KHQ88_02005	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHQ88_02015	COG1228	amidohydrolase
KHQ88_02020	COG3404	Formiminotransferase-cyclodeaminase
KHQ88_02025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHQ88_02030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHQ88_02040	COG0577	efflux transmembrane transporter activity
KHQ88_02040	COG1136	(ABC) transporter
KHQ88_02045	COG0156	8-amino-7-oxononanoate synthase activity
KHQ88_02050	COG0300	oxidoreductase activity
KHQ88_02100	COG5001	Diguanylate cyclase
KHQ88_02100	COG3300	MHYT domain
KHQ88_02105	COG0386	Belongs to the glutathione peroxidase family
KHQ88_02110	COG2814	Major facilitator Superfamily
KHQ88_02115	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KHQ88_02125	COG3457	Alanine racemase
KHQ88_02135	COG5012	cobalamin binding
KHQ88_02145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHQ88_02155	COG3804	dihydrodipicolinate reductase
KHQ88_02165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHQ88_02175	COG0116	Belongs to the methyltransferase superfamily
KHQ88_02190	COG1342	Belongs to the UPF0251 family
KHQ88_02200	COG0450	alkyl hydroperoxide reductase
KHQ88_02210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHQ88_02215	COG0336	Belongs to the RNA methyltransferase TrmD family
KHQ88_02220	COG0335	large ribosomal subunit rRNA binding
KHQ88_02235	COG1253	flavin adenine dinucleotide binding
KHQ88_02240	COG2217	Heavy metal translocating P-type atpase
KHQ88_02245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHQ88_02250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KHQ88_02255	COG1363	Peptidase, m42
KHQ88_02265	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHQ88_02275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHQ88_02280	COG0237	dephospho-CoA kinase activity
KHQ88_02285	COG3611	Membrane attachment protein
KHQ88_02290	COG1484	DNA-dependent DNA replication
KHQ88_02295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHQ88_02300	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KHQ88_02305	COG0194	GDP metabolic process
KHQ88_02315	COG2176	DNA-directed DNA polymerase activity
KHQ88_02325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHQ88_02330	COG0072	phenylalanine-tRNA ligase activity
KHQ88_02330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ88_02335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHQ88_02345	COG1592	Rubrerythrin
KHQ88_02350	COG1162	GTPase activity
KHQ88_02355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHQ88_02365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ88_02370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ88_02375	COG0251	oxidation-reduction process
KHQ88_02380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KHQ88_02385	COG1461	Dihydroxyacetone kinase
KHQ88_02390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHQ88_02395	COG0416	fatty acid biosynthetic process
KHQ88_02410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHQ88_02420	COG0489	protein tyrosine kinase activity
KHQ88_02435	COG0275	rRNA processing
KHQ88_02450	COG0668	transmembrane transport
KHQ88_02455	COG1136	(ABC) transporter
KHQ88_02460	COG4591	ABC-type transport system involved in lipoprotein release permease component
KHQ88_02470	COG0017	Asparaginyl-tRNA synthetase
KHQ88_02475	COG0564	pseudouridine synthase activity
KHQ88_02480	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHQ88_02485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHQ88_02505	COG1307	EDD domain protein, DegV family
KHQ88_02510	COG1132	(ABC) transporter
KHQ88_02515	COG1132	(ABC) transporter
KHQ88_02525	COG1132	(ABC) transporter
KHQ88_02530	COG1132	(ABC) transporter
KHQ88_02535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHQ88_02545	COG1473	amidohydrolase
KHQ88_02575	COG0180	Tryptophanyl-tRNA synthetase
KHQ88_02585	COG1393	Belongs to the ArsC family
KHQ88_02600	COG0006	proline dipeptidase activity
KHQ88_02605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHQ88_02610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHQ88_02615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHQ88_02620	COG3906	Belongs to the UPF0473 family
KHQ88_02625	COG4122	O-methyltransferase activity
KHQ88_02635	COG0826	peptidase U32
KHQ88_02640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHQ88_02655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KHQ88_02660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHQ88_02670	COG0799	negative regulation of ribosome biogenesis
KHQ88_02675	COG2226	methyltransferase
KHQ88_02680	COG1555	photosystem II stabilization
KHQ88_02680	COG1596	polysaccharide export
KHQ88_02690	COG1466	dna polymerase III delta subunit
KHQ88_02695	COG0268	Binds directly to 16S ribosomal RNA
KHQ88_02705	COG0469	pyruvate kinase activity
KHQ88_02745	COG0745	RESPONSE REGULATOR receiver
KHQ88_02750	COG5002	protein histidine kinase activity
KHQ88_02755	COG5646	InterPro IPR014922
KHQ88_02790	COG0488	(ABC) transporter
KHQ88_02795	COG0018	arginyl-trna synthetase
KHQ88_02800	COG1132	(ABC) transporter
KHQ88_02805	COG1132	(ABC) transporter
KHQ88_02825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHQ88_02850	COG0601	transmembrane transport
KHQ88_02855	COG1012	belongs to the aldehyde dehydrogenase family
KHQ88_02880	COG1230	cation diffusion facilitator family transporter
KHQ88_02895	COG0318	PFAM AMP-dependent synthetase and ligase
KHQ88_02900	COG1309	transcriptional regulator
KHQ88_02925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHQ88_02950	COG0402	S-adenosylhomocysteine deaminase activity
KHQ88_02955	COG0167	dihydroorotate dehydrogenase activity
KHQ88_02960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHQ88_02975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHQ88_02985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHQ88_02990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHQ88_02995	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHQ88_03005	COG0590	tRNA wobble adenosine to inosine editing
KHQ88_03025	COG0509	glycine decarboxylation via glycine cleavage system
KHQ88_03030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHQ88_03035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHQ88_03045	COG2199	diguanylate cyclase activity
KHQ88_03050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHQ88_03055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHQ88_03060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHQ88_03075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHQ88_03085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ88_03090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHQ88_03120	COG0667	Aldo Keto reductase
KHQ88_03125	COG1940	carbohydrate kinase activity
KHQ88_03130	COG2115	Belongs to the xylose isomerase family
KHQ88_03135	COG1070	Carbohydrate kinase
KHQ88_03140	COG1129	ABC transporter
KHQ88_03145	COG4214	carbohydrate transport
KHQ88_03160	COG0673	inositol 2-dehydrogenase activity
KHQ88_03165	COG1420	regulation of RNA biosynthetic process
KHQ88_03170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHQ88_03175	COG0443	Heat shock 70 kDa protein
KHQ88_03185	COG1695	Transcriptional regulator
KHQ88_03205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHQ88_03210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHQ88_03220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHQ88_03225	COG1702	phosphate starvation-inducible protein PhoH
KHQ88_03230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHQ88_03235	COG0295	cytidine deaminase activity
KHQ88_03240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHQ88_03245	COG1381	Involved in DNA repair and RecF pathway recombination
KHQ88_03260	COG0423	glycine-tRNA ligase activity
KHQ88_03265	COG0358	DNA primase activity
KHQ88_03270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHQ88_03280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHQ88_03285	COG1307	EDD domain protein, DegV family
KHQ88_03300	COG3763	UPF0154 protein
KHQ88_03305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KHQ88_03310	COG0187	DNA topoisomerase II activity
KHQ88_03315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHQ88_03330	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KHQ88_03330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHQ88_03335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHQ88_03340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHQ88_03345	COG1490	D-aminoacyl-tRNA deacylase activity
KHQ88_03350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHQ88_03355	COG0124	histidyl-tRNA synthetase
KHQ88_03360	COG0628	permease
KHQ88_03370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KHQ88_03395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHQ88_03400	COG0564	pseudouridine synthase activity
KHQ88_03405	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHQ88_03410	COG1193	negative regulation of DNA recombination
KHQ88_03415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHQ88_03420	COG0196	riboflavin kinase activity
KHQ88_03430	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHQ88_03435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHQ88_03445	COG1051	belongs to the nudix hydrolase family
KHQ88_03455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHQ88_03460	COG1185	polyribonucleotide nucleotidyltransferase activity
KHQ88_03470	COG0481	GTPase activity
KHQ88_03475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHQ88_03480	COG4974	Belongs to the 'phage' integrase family
KHQ88_03485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHQ88_03500	COG2255	four-way junction helicase activity
KHQ88_03505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHQ88_03510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHQ88_03515	COG4869	propanediol catabolic process
KHQ88_03525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHQ88_03530	COG2239	Acts as a magnesium transporter
KHQ88_03535	COG2239	Acts as a magnesium transporter
KHQ88_03545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KHQ88_03550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHQ88_03555	COG1799	cell septum assembly
KHQ88_03565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHQ88_03570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHQ88_03585	COG0612	Peptidase, M16
KHQ88_03595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KHQ88_03610	COG0525	valine-tRNA ligase activity
KHQ88_03620	COG2003	Belongs to the UPF0758 family
KHQ88_03645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHQ88_03660	COG0629	single-stranded DNA binding
KHQ88_03665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHQ88_03670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHQ88_03680	COG2059	Chromate
KHQ88_03705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ88_03720	COG0737	Belongs to the 5'-nucleotidase family
KHQ88_03730	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHQ88_03755	COG0174	glutamine synthetase
KHQ88_03765	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHQ88_03770	COG0426	domain, Protein
KHQ88_03775	COG1215	transferase activity, transferring glycosyl groups
KHQ88_03780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHQ88_03795	COG0632	four-way junction helicase activity
KHQ88_03800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHQ88_03815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHQ88_03845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHQ88_03850	COG0742	ribosomal rna small subunit methyltransferase
KHQ88_03855	COG0574	Belongs to the PEP-utilizing enzyme family
KHQ88_03855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHQ88_03865	COG4555	ABC transporter
KHQ88_03875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHQ88_03885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHQ88_03920	COG1668	transmembrane transport
KHQ88_03925	COG4555	ABC transporter
KHQ88_03930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHQ88_03935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KHQ88_03945	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHQ88_03950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHQ88_03965	COG1129	ABC transporter
KHQ88_03990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHQ88_03990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHQ88_03995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHQ88_04000	COG1363	Peptidase, m42
KHQ88_04005	COG0564	pseudouridine synthase activity
KHQ88_04010	COG3557	Belongs to the UPF0374 family
KHQ88_04020	COG0513	Belongs to the DEAD box helicase family
KHQ88_04025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHQ88_04035	COG0497	DNA recombination
KHQ88_04040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHQ88_04045	COG1722	exodeoxyribonuclease VII activity
KHQ88_04050	COG1570	exodeoxyribonuclease VII activity
KHQ88_04055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHQ88_04070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHQ88_04075	COG0569	domain protein
KHQ88_04090	COG0745	RESPONSE REGULATOR receiver
KHQ88_04095	COG0704	Plays a role in the regulation of phosphate uptake
KHQ88_04100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHQ88_04105	COG0581	inorganic phosphate transmembrane transporter activity
KHQ88_04110	COG0573	inorganic phosphate transmembrane transporter activity
KHQ88_04115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHQ88_04120	COG0776	regulation of translation
KHQ88_04125	COG1160	GTP binding
KHQ88_04135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHQ88_04140	COG1187	pseudouridine synthase activity
KHQ88_04145	COG4536	flavin adenine dinucleotide binding
KHQ88_04150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHQ88_04160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHQ88_04180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHQ88_04185	COG1692	metallophosphoesterase
KHQ88_04200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHQ88_04205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHQ88_04215	COG2996	Protein conserved in bacteria
KHQ88_04250	COG1074	ATP-dependent DNA helicase activity
KHQ88_04260	COG1368	sulfuric ester hydrolase activity
KHQ88_04265	COG0071	Belongs to the small heat shock protein (HSP20) family
KHQ88_04275	COG1045	serine acetyltransferase
KHQ88_04285	COG1104	cysteine desulfurase activity
KHQ88_04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHQ88_04300	COG0542	response to heat
KHQ88_04305	COG3300	MHYT domain
KHQ88_04305	COG5001	Diguanylate cyclase
KHQ88_04310	COG5001	Diguanylate cyclase
KHQ88_04310	COG4251	negative regulation of phosphorylation
KHQ88_04310	COG3706	GGDEF domain
KHQ88_04310	COG2203	Gaf domain
KHQ88_04315	COG1970	mechanosensitive ion channel activity
KHQ88_04345	COG1595	DNA-templated transcription, initiation
KHQ88_04365	COG5646	InterPro IPR014922
KHQ88_04445	COG4886	Leucine-rich repeat (LRR) protein
KHQ88_04445	COG4932	domain protein
KHQ88_04450	COG2070	2-Nitropropane dioxygenase
KHQ88_04455	COG1525	nuclease
KHQ88_04470	COG0330	HflC and HflK could
KHQ88_04475	COG0513	Belongs to the DEAD box helicase family
KHQ88_04500	COG2089	acid synthase
KHQ88_04505	COG3980	spore coat polysaccharide biosynthesis protein
KHQ88_04510	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KHQ88_04515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHQ88_04520	COG1086	Polysaccharide biosynthesis protein
KHQ88_04565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHQ88_04570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHQ88_04585	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHQ88_04610	COG1609	Transcriptional regulator
KHQ88_04625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHQ88_04640	COG0572	uridine kinase
KHQ88_04645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHQ88_04650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHQ88_04655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHQ88_04660	COG1120	ATPase activity
KHQ88_04670	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KHQ88_04675	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ88_04690	COG0511	ligase activity, forming carbon-carbon bonds
KHQ88_04695	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KHQ88_04710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHQ88_04720	COG1509	lysine 2,3-aminomutase activity
KHQ88_04730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHQ88_04735	COG1121	(ABC) transporter
KHQ88_04740	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHQ88_04760	COG0765	amino acid transport
KHQ88_04765	COG1126	abc transporter atp-binding protein
KHQ88_04775	COG2202	Pas domain
KHQ88_04775	COG2200	EAL domain
KHQ88_04775	COG2199	diguanylate cyclase activity
KHQ88_04780	COG3426	butyrate kinase activity
KHQ88_04785	COG0280	phosphate acetyltransferase
KHQ88_04815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHQ88_04820	COG2356	endonuclease I
KHQ88_04845	COG1765	OsmC-like protein
KHQ88_04850	COG1012	belongs to the aldehyde dehydrogenase family
KHQ88_04880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHQ88_04890	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHQ88_04895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHQ88_04900	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHQ88_04905	COG0534	Mate efflux family protein
KHQ88_04920	COG0205	6-phosphofructokinase activity
KHQ88_04930	COG0156	8-amino-7-oxononanoate synthase activity
KHQ88_04935	COG1063	alcohol dehydrogenase
KHQ88_04950	COG4152	abc transporter atp-binding protein
KHQ88_04970	COG1368	sulfuric ester hydrolase activity
KHQ88_04975	COG0154	amidase activity
KHQ88_04985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHQ88_04985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHQ88_04990	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KHQ88_05010	COG4608	Belongs to the ABC transporter superfamily
KHQ88_05015	COG0444	Belongs to the ABC transporter superfamily
KHQ88_05015	COG0444	Belongs to the ABC transporter superfamily
KHQ88_05020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ88_05025	COG0601	transmembrane transport
KHQ88_05050	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KHQ88_05095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHQ88_05110	COG1272	protein, Hemolysin III
KHQ88_05120	COG0698	ribose 5-phosphate isomerase
KHQ88_05125	COG1126	abc transporter atp-binding protein
KHQ88_05130	COG0765	amino acid transport
KHQ88_05140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHQ88_05165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHQ88_05165	COG0426	domain, Protein
KHQ88_05190	COG0708	Exodeoxyribonuclease III
KHQ88_05195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ88_05205	COG1131	(ABC) transporter
KHQ88_05215	COG0306	phosphate transporter
KHQ88_05245	COG2801	Transposase and inactivated derivatives
KHQ88_05265	COG2217	Heavy metal translocating P-type atpase
KHQ88_05270	COG0745	RESPONSE REGULATOR receiver
KHQ88_05295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHQ88_05300	COG0557	exoribonuclease II activity
KHQ88_05310	COG0148	phosphopyruvate hydratase activity
KHQ88_05320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHQ88_05345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHQ88_05350	COG0778	Nitroreductase
KHQ88_05365	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHQ88_05370	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KHQ88_05375	COG0058	SHG alpha-glucan phosphorylase activity
KHQ88_05380	COG0297	glycogen (starch) synthase activity
KHQ88_05400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHQ88_05405	COG0653	protein targeting
KHQ88_05410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHQ88_05420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHQ88_05425	COG0495	leucyl-tRNA aminoacylation
KHQ88_05435	COG1242	4 iron, 4 sulfur cluster binding
KHQ88_05440	COG0697	spore germination
KHQ88_05445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHQ88_05455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHQ88_05465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHQ88_05470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHQ88_05475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHQ88_05480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHQ88_05495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHQ88_05500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHQ88_05510	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHQ88_05515	COG0195	Participates in both transcription termination and antitermination
KHQ88_05520	COG0779	Required for maturation of 30S ribosomal subunits
KHQ88_05530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ88_05540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHQ88_05545	COG0301	tRNA thio-modification
KHQ88_05550	COG1956	GAF domain-containing protein
KHQ88_05555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHQ88_05560	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ88_05570	COG0126	phosphoglycerate kinase activity
KHQ88_05580	COG3870	Protein conserved in bacteria
KHQ88_05600	COG0822	iron-sulfur transferase activity
KHQ88_05605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHQ88_05610	COG0719	Fe-S assembly protein
KHQ88_05615	COG0396	ATPase activity
KHQ88_05620	COG1285	pathogenesis
KHQ88_05625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHQ88_05640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHQ88_05685	COG2267	carboxylic ester hydrolase activity
KHQ88_05690	COG0596	Alpha beta hydrolase
KHQ88_05695	COG0427	acetyl-CoA hydrolase
KHQ88_05730	COG1028	Short-chain dehydrogenase reductase Sdr
KHQ88_05735	COG0183	Belongs to the thiolase family
KHQ88_05740	COG1309	transcriptional regulator
KHQ88_05745	COG5001	Diguanylate cyclase
KHQ88_05745	COG4251	negative regulation of phosphorylation
KHQ88_05745	COG3706	GGDEF domain
KHQ88_05745	COG2203	Gaf domain
KHQ88_05750	COG5001	Diguanylate cyclase
KHQ88_05750	COG1716	ATPase activity
KHQ88_05770	COG3481	metal-dependent phosphohydrolase, HD sub domain
KHQ88_05775	COG1523	belongs to the glycosyl hydrolase 13 family
KHQ88_05785	COG1739	Uncharacterized protein family UPF0029
KHQ88_05830	COG2199	diguanylate cyclase activity
KHQ88_05845	COG1837	Belongs to the UPF0109 family
KHQ88_05850	COG0228	four-way junction DNA binding
KHQ88_05870	COG3579	cysteine-type endopeptidase activity
KHQ88_05880	COG0493	'glutamate synthase
KHQ88_05910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KHQ88_05915	COG3706	GGDEF domain
KHQ88_05930	COG0671	phosphoesterase, PA-phosphatase related
KHQ88_05935	COG2252	PERMEase
KHQ88_05980	COG1132	(ABC) transporter
KHQ88_06045	COG2514	catechol 2,3-dioxygenase activity
KHQ88_06055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHQ88_06060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHQ88_06065	COG3681	Belongs to the UPF0597 family
KHQ88_06070	COG0501	Belongs to the peptidase M48B family
KHQ88_06110	COG0651	ATP synthesis coupled electron transport
KHQ88_06115	COG0651	ATP synthesis coupled electron transport
KHQ88_06120	COG0651	ATP synthesis coupled electron transport
KHQ88_06130	COG2111	Na H antiporter
KHQ88_06145	COG1320	monovalent cation:proton antiporter activity
KHQ88_06150	COG2212	antiporter activity
KHQ88_06160	COG1454	alcohol dehydrogenase
KHQ88_06185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHQ88_06190	COG1459	type II secretion system
KHQ88_06195	COG2165	general secretion pathway protein
KHQ88_06210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHQ88_06225	COG0753	catalase activity
KHQ88_06230	COG2832	Protein of unknown function (DUF454)
KHQ88_06250	COG3022	response to hydroperoxide
KHQ88_06255	COG1368	sulfuric ester hydrolase activity
KHQ88_06260	COG1373	ATPase (AAA superfamily
KHQ88_06310	COG0641	radical SAM
KHQ88_06355	COG0750	zinc metalloprotease
KHQ88_06360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KHQ88_06365	COG4589	Belongs to the CDS family
KHQ88_06375	COG0233	cytoplasmic translational termination
KHQ88_06385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHQ88_06395	COG0756	dUTP diphosphatase activity
KHQ88_06400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHQ88_06405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHQ88_06410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHQ88_06415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHQ88_06420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHQ88_06425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHQ88_06435	COG0356	it plays a direct role in the translocation of protons across the membrane
KHQ88_06450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHQ88_06460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHQ88_06465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHQ88_06470	COG0681	Belongs to the peptidase S26 family
KHQ88_06475	COG1674	ftsk spoiiie
KHQ88_06485	COG0561	phosphatase activity
KHQ88_06490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHQ88_06495	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHQ88_06500	COG0552	protein localization to endoplasmic reticulum
KHQ88_06505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHQ88_06515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHQ88_06520	COG0305	Participates in initiation and elongation during chromosome replication
KHQ88_06525	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KHQ88_06525	COG0359	binds to the 23S rRNA
KHQ88_06530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHQ88_06535	COG0629	single-stranded DNA binding
KHQ88_06540	COG0360	Binds together with S18 to 16S ribosomal RNA
KHQ88_06555	COG1058	Belongs to the CinA family
KHQ88_06555	COG1546	Belongs to the CinA family
KHQ88_06560	COG0012	GTP binding
KHQ88_06565	COG0084	hydrolase, TatD family'
KHQ88_06570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHQ88_06580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHQ88_06585	COG0049	tRNA binding
KHQ88_06590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHQ88_06605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KHQ88_06610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KHQ88_06645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHQ88_06650	COG0085	RNA polymerase activity
KHQ88_06655	COG2813	Specifically methylates the guanine in position
KHQ88_06660	COG0222	ribosome binding
KHQ88_06670	COG0081	regulation of translation
KHQ88_06675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHQ88_06680	COG1136	(ABC) transporter
KHQ88_06685	COG0577	efflux transmembrane transporter activity
KHQ88_06685	COG1136	(ABC) transporter
KHQ88_06690	COG0250	Participates in transcription elongation, termination and antitermination
KHQ88_06700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ88_06710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ88_06720	COG0215	cysteine-tRNA ligase activity
KHQ88_06725	COG1278	Cold shock
KHQ88_06735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHQ88_06745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KHQ88_06765	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHQ88_06770	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KHQ88_06775	COG1774	PSP1 C-terminal conserved region
KHQ88_06780	COG0470	DNA polymerase III
KHQ88_06785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHQ88_06790	COG1121	(ABC) transporter
KHQ88_06795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHQ88_06800	COG0101	tRNA pseudouridine synthase activity
KHQ88_06805	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHQ88_06810	COG1122	ATPase activity
KHQ88_06815	COG1122	ATPase activity
KHQ88_06825	COG0203	ribosomal protein L17
KHQ88_06830	COG0202	RNA polymerase activity
KHQ88_06835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHQ88_06845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHQ88_06850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHQ88_06855	COG0024	Methionine aminopeptidase
KHQ88_06865	COG0201	protein transport
KHQ88_06885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHQ88_06890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHQ88_06895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHQ88_06900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHQ88_06905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHQ88_06910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHQ88_06915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHQ88_06925	COG0255	Belongs to the universal ribosomal protein uL29 family
KHQ88_06935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHQ88_06945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHQ88_06950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHQ88_06955	COG0089	rRNA binding
KHQ88_06960	COG0088	Forms part of the polypeptide exit tunnel
KHQ88_06965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHQ88_06970	COG0051	transcription antitermination factor activity, RNA binding
KHQ88_06975	COG1199	ATP-dependent helicase activity
KHQ88_06975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KHQ88_06990	COG1979	alcohol dehydrogenase
KHQ88_06995	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ88_07020	COG0656	L-ascorbic acid biosynthetic process
KHQ88_07025	COG1671	Belongs to the UPF0178 family
KHQ88_07050	COG2801	Transposase and inactivated derivatives
KHQ88_07135	COG1475	DNA binding
KHQ88_07155	COG0357	Ribosomal RNA small subunit methyltransferase G
KHQ88_07165	COG0561	phosphatase activity
KHQ88_07180	COG1435	thymidine kinase activity
KHQ88_07185	COG0254	rRNA binding
KHQ88_07190	COG0281	malic enzyme
KHQ88_07195	COG0424	maF-like protein
KHQ88_07200	COG0037	tRNA processing
KHQ88_07200	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHQ88_07205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHQ88_07210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHQ88_07220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHQ88_07245	COG0191	fructose-bisphosphate aldolase activity
KHQ88_07250	COG0312	modulator of DNA gyrase
KHQ88_07255	COG0312	modulator of DNA gyrase
KHQ88_07260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KHQ88_07275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ88_07285	COG2356	endonuclease I
KHQ88_07305	COG0395	ABC-type sugar transport system, permease component
KHQ88_07310	COG1175	transmembrane transport
KHQ88_07315	COG3842	ATPase activity
KHQ88_07325	COG1525	nuclease
KHQ88_07335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHQ88_07340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHQ88_07345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHQ88_07360	COG0037	tRNA processing
KHQ88_07395	COG0017	Asparaginyl-tRNA synthetase
KHQ88_07410	COG2088	sporulation resulting in formation of a cellular spore
KHQ88_07415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHQ88_07425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ88_07430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHQ88_07440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHQ88_07445	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHQ88_07450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHQ88_07460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KHQ88_07475	COG0488	(ABC) transporter
KHQ88_07480	COG0592	DNA-directed DNA polymerase activity
KHQ88_07485	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHQ88_07495	COG0594	ribonuclease P activity
KHQ88_07500	COG0706	membrane insertase activity
KHQ88_07510	COG0193	aminoacyl-tRNA hydrolase activity
KHQ88_07515	COG0537	adenosine 5'-monophosphoramidase activity
KHQ88_07525	COG1597	lipid kinase activity
KHQ88_07530	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHQ88_07535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHQ88_07540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHQ88_07545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHQ88_07550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHQ88_07570	COG0463	Glycosyl transferase, family 2
KHQ88_07580	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHQ88_07600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHQ88_07610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHQ88_07615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)