locus-tag	class	description
KHQ81_00080	COG0629	single-stranded DNA binding
KHQ81_00130	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KHQ81_00150	COG0596	Alpha beta hydrolase
KHQ81_00170	COG1193	negative regulation of DNA recombination
KHQ81_00185	COG1131	(ABC) transporter
KHQ81_00195	COG0789	Transcriptional regulator
KHQ81_00200	COG0833	amino acid
KHQ81_00205	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ81_00215	COG1288	antiporter activity
KHQ81_00245	COG1309	transcriptional regulator
KHQ81_00260	COG4565	transcriptional regulatory protein
KHQ81_00265	COG3290	protein histidine kinase activity
KHQ81_00270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHQ81_00295	COG1357	PFAM Pentapeptide repeats (8 copies)
KHQ81_00330	COG1136	(ABC) transporter
KHQ81_00385	COG2894	cell division
KHQ81_00405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHQ81_00420	COG2801	Transposase and inactivated derivatives
KHQ81_00445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHQ81_00460	COG0360	Binds together with S18 to 16S ribosomal RNA
KHQ81_00470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHQ81_00480	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KHQ81_00485	COG0359	binds to the 23S rRNA
KHQ81_00490	COG0305	Participates in initiation and elongation during chromosome replication
KHQ81_00525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHQ81_00550	COG2801	Transposase and inactivated derivatives
KHQ81_00555	COG2890	protein-(glutamine-N5) methyltransferase activity
KHQ81_00630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHQ81_00635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHQ81_00640	COG0148	phosphopyruvate hydratase activity
KHQ81_00645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHQ81_00685	COG0194	GDP metabolic process
KHQ81_00760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KHQ81_00780	COG0571	ribonuclease III activity
KHQ81_00785	COG0601	transmembrane transport
KHQ81_00790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ81_00795	COG0444	Belongs to the ABC transporter superfamily
KHQ81_00800	COG4608	Belongs to the ABC transporter superfamily
KHQ81_00805	COG4166	transmembrane transport
KHQ81_00830	COG0577	efflux transmembrane transporter activity
KHQ81_00830	COG1136	(ABC) transporter
KHQ81_00855	COG1132	(ABC) transporter
KHQ81_00860	COG1132	(ABC) transporter
KHQ81_00865	COG2801	Transposase and inactivated derivatives
KHQ81_00905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHQ81_00955	COG2746	aminoglycoside 3-N-acetyltransferase activity
KHQ81_00960	COG1388	LysM domain
KHQ81_00960	COG3942	CHAP domain
KHQ81_00975	COG0640	Transcriptional regulator
KHQ81_00980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHQ81_00985	COG0798	PFAM Bile acid sodium symporter
KHQ81_00995	COG1671	Belongs to the UPF0178 family
KHQ81_01015	COG0527	aspartate kinase activity
KHQ81_01020	COG0460	homoserine dehydrogenase
KHQ81_01025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHQ81_01030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHQ81_01040	COG4492	Belongs to the UPF0735 family
KHQ81_01045	COG3620	sequence-specific DNA binding
KHQ81_01055	COG3344	reverse transcriptase
KHQ81_01075	COG3711	transcriptional antiterminator
KHQ81_01080	COG1263	PTS System
KHQ81_01080	COG2190	(PTS) system
KHQ81_01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHQ81_01095	COG4214	carbohydrate transport
KHQ81_01110	COG0577	efflux transmembrane transporter activity
KHQ81_01110	COG1136	(ABC) transporter
KHQ81_01115	COG1136	(ABC) transporter
KHQ81_01115	COG0577	efflux transmembrane transporter activity
KHQ81_01145	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KHQ81_01180	COG0395	ABC-type sugar transport system, permease component
KHQ81_01200	COG1175	transmembrane transport
KHQ81_01205	COG0395	ABC-type sugar transport system, permease component
KHQ81_01280	COG0488	(ABC) transporter
KHQ81_01295	COG0281	malic enzyme
KHQ81_01300	COG2390	Transcriptional regulator
KHQ81_01320	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KHQ81_01330	COG1979	alcohol dehydrogenase
KHQ81_01335	COG0697	spore germination
KHQ81_01350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHQ81_01355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHQ81_01360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHQ81_01380	COG3069	C4-dicarboxylate transmembrane transporter activity
KHQ81_01415	COG0395	ABC-type sugar transport system, permease component
KHQ81_01435	COG0395	ABC-type sugar transport system, permease component
KHQ81_01450	COG1609	Transcriptional regulator
KHQ81_01455	COG3459	Glycosyltransferase 36 associated
KHQ81_01465	COG1501	Belongs to the glycosyl hydrolase 31 family
KHQ81_01515	COG0488	(ABC) transporter
KHQ81_01530	COG2801	Transposase and inactivated derivatives
KHQ81_01560	COG0514	ATP-dependent DNA helicase (RecQ)
KHQ81_01605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHQ81_01610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHQ81_01615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHQ81_01620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KHQ81_01625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHQ81_01635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHQ81_01640	COG0138	bifunctional purine biosynthesis protein purh
KHQ81_01645	COG0151	Belongs to the GarS family
KHQ81_01650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHQ81_01700	COG0003	Pfam Anion-transporting ATPase
KHQ81_01715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KHQ81_01715	COG0519	Catalyzes the synthesis of GMP from XMP
KHQ81_01720	COG0516	GMP reductase activity
KHQ81_01720	COG0517	IMP dehydrogenase activity
KHQ81_01725	COG0366	Alpha amylase catalytic
KHQ81_01730	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ81_01740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHQ81_01750	COG1116	anion transmembrane transporter activity
KHQ81_01760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHQ81_01765	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KHQ81_01775	COG0492	ferredoxin-NADP+ reductase activity
KHQ81_01785	COG0705	Rhomboid family
KHQ81_01785	COG0457	Tetratricopeptide repeat
KHQ81_01805	COG1846	Transcriptional regulator
KHQ81_01820	COG0501	Belongs to the peptidase M48B family
KHQ81_01825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHQ81_01835	COG1136	(ABC) transporter
KHQ81_01850	COG4585	Histidine kinase
KHQ81_01865	COG2801	Transposase and inactivated derivatives
KHQ81_01870	COG2707	UPF0756 membrane protein
KHQ81_01880	COG2309	aminopeptidase activity
KHQ81_01890	COG0071	Belongs to the small heat shock protein (HSP20) family
KHQ81_01910	COG0038	chloride channel
KHQ81_01915	COG2226	methyltransferase
KHQ81_01965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHQ81_01970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHQ81_02000	COG0395	ABC-type sugar transport system, permease component
KHQ81_02020	COG1175	transmembrane transport
KHQ81_02025	COG0395	ABC-type sugar transport system, permease component
KHQ81_02035	COG3876	Protein conserved in bacteria
KHQ81_02040	COG1472	Belongs to the glycosyl hydrolase 3 family
KHQ81_02045	COG2971	BadF BadG BcrA BcrD
KHQ81_02050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KHQ81_02060	COG1737	Transcriptional regulator
KHQ81_02065	COG1649	PFAM Uncharacterised BCR, COG1649
KHQ81_02070	COG2086	electron transfer activity
KHQ81_02080	COG0277	FAD linked oxidase domain protein
KHQ81_02095	COG1929	Belongs to the glycerate kinase type-1 family
KHQ81_02105	COG1194	a g-specific adenine glycosylase
KHQ81_02115	COG0493	'glutamate synthase
KHQ81_02115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KHQ81_02125	COG1472	Belongs to the glycosyl hydrolase 3 family
KHQ81_02135	COG0366	Alpha amylase catalytic
KHQ81_02155	COG1132	(ABC) transporter
KHQ81_02160	COG1132	(ABC) transporter
KHQ81_02165	COG1132	(ABC) transporter
KHQ81_02170	COG1132	(ABC) transporter
KHQ81_02180	COG2826	transposase and inactivated derivatives, IS30 family
KHQ81_02255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KHQ81_02260	COG3858	chitin binding
KHQ81_02260	COG1388	LysM domain
KHQ81_02265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ81_02275	COG1309	transcriptional regulator
KHQ81_02280	COG0183	Belongs to the thiolase family
KHQ81_02285	COG1028	Short-chain dehydrogenase reductase Sdr
KHQ81_02295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHQ81_02325	COG0427	acetyl-CoA hydrolase
KHQ81_02330	COG2267	carboxylic ester hydrolase activity
KHQ81_02335	COG0183	Belongs to the thiolase family
KHQ81_02340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHQ81_02345	COG0406	alpha-ribazole phosphatase activity
KHQ81_02350	COG3842	ATPase activity
KHQ81_02355	COG1175	transmembrane transport
KHQ81_02360	COG3833	ABC-type maltose transport systems, permease component
KHQ81_02385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ81_02390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ81_02400	COG1408	metallophosphoesterase
KHQ81_02410	COG1376	ErfK ybiS ycfS ynhG family protein
KHQ81_02420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHQ81_02425	COG0577	efflux transmembrane transporter activity
KHQ81_02425	COG1136	(ABC) transporter
KHQ81_02430	COG1136	(ABC) transporter
KHQ81_02430	COG0577	efflux transmembrane transporter activity
KHQ81_02440	COG1307	EDD domain protein, DegV family
KHQ81_02450	COG0561	phosphatase activity
KHQ81_02455	COG1307	EDD domain protein, DegV family
KHQ81_02470	COG2996	Protein conserved in bacteria
KHQ81_02485	COG1131	(ABC) transporter
KHQ81_02505	COG2385	sporulation resulting in formation of a cellular spore
KHQ81_02525	COG4120	Belongs to the binding-protein-dependent transport system permease family
KHQ81_02530	COG3842	ATPase activity
KHQ81_02550	COG1924	4 iron, 4 sulfur cluster binding
KHQ81_02575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHQ81_02645	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KHQ81_02720	COG1131	(ABC) transporter
KHQ81_02725	COG1131	(ABC) transporter
KHQ81_02740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHQ81_02745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHQ81_02780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHQ81_02840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KHQ81_02845	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KHQ81_02855	COG0494	nUDIX hydrolase
KHQ81_02865	COG2268	Band 7 protein
KHQ81_02920	COG2801	Transposase and inactivated derivatives
KHQ81_02945	COG0824	Thioesterase
KHQ81_02970	COG0564	pseudouridine synthase activity
KHQ81_02975	COG0668	transmembrane transport
KHQ81_02980	COG2304	oxidoreductase activity
KHQ81_02990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHQ81_03000	COG0735	belongs to the Fur family
KHQ81_03005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHQ81_03010	COG1121	(ABC) transporter
KHQ81_03015	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHQ81_03025	COG0557	exoribonuclease II activity
KHQ81_03040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ81_03045	COG0640	Transcriptional regulator
KHQ81_03050	COG2217	Heavy metal translocating P-type atpase
KHQ81_03060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KHQ81_03065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHQ81_03075	COG2137	regulation of response to DNA damage stimulus
KHQ81_03085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHQ81_03095	COG0058	SHG alpha-glucan phosphorylase activity
KHQ81_03100	COG1523	belongs to the glycosyl hydrolase 13 family
KHQ81_03120	COG1937	Protein conserved in bacteria
KHQ81_03125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHQ81_03130	COG3481	metal-dependent phosphohydrolase, HD sub domain
KHQ81_03135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHQ81_03155	COG1116	anion transmembrane transporter activity
KHQ81_03170	COG2878	Part of a membrane complex involved in electron transport
KHQ81_03215	COG0601	transmembrane transport
KHQ81_03220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ81_03225	COG0444	Belongs to the ABC transporter superfamily
KHQ81_03230	COG4608	Belongs to the ABC transporter superfamily
KHQ81_03240	COG0396	ATPase activity
KHQ81_03245	COG0719	Fe-S assembly protein
KHQ81_03250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHQ81_03255	COG0822	iron-sulfur transferase activity
KHQ81_03260	COG0719	Fe-S assembly protein
KHQ81_03270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHQ81_03275	COG0517	IMP dehydrogenase activity
KHQ81_03280	COG3377	Domain of unknown function (DUF1805)
KHQ81_03295	COG0647	UMP catabolic process
KHQ81_03320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHQ81_03330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHQ81_03335	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KHQ81_03340	COG0492	ferredoxin-NADP+ reductase activity
KHQ81_03345	COG1098	S1 RNA binding domain
KHQ81_03350	COG0166	Belongs to the GPI family
KHQ81_03355	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHQ81_03360	COG0426	domain, Protein
KHQ81_03370	COG0802	atpase or kinase
KHQ81_03375	COG1214	PFAM Peptidase M22, glycoprotease
KHQ81_03380	COG0456	acetyltransferase
KHQ81_03385	COG1523	belongs to the glycosyl hydrolase 13 family
KHQ81_03400	COG3409	Peptidoglycan-binding domain 1 protein
KHQ81_03400	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHQ81_03415	COG0601	transmembrane transport
KHQ81_03420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ81_03425	COG0444	Belongs to the ABC transporter superfamily
KHQ81_03430	COG4608	Belongs to the ABC transporter superfamily
KHQ81_03440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHQ81_03445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KHQ81_03450	COG2080	2 iron, 2 sulfur cluster binding
KHQ81_03455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHQ81_03460	COG0493	'glutamate synthase
KHQ81_03460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KHQ81_03465	COG0402	S-adenosylhomocysteine deaminase activity
KHQ81_03470	COG1309	transcriptional regulator
KHQ81_03480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHQ81_03500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHQ81_03505	COG0402	S-adenosylhomocysteine deaminase activity
KHQ81_03510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHQ81_03535	COG0640	Transcriptional regulator
KHQ81_03560	COG2078	PFAM AMMECR1 domain protein
KHQ81_03560	COG3885	ferrous iron binding
KHQ81_03575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHQ81_03590	COG0488	(ABC) transporter
KHQ81_03600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHQ81_03605	COG0459	protein refolding
KHQ81_03635	COG0668	transmembrane transport
KHQ81_03640	COG0210	DNA helicase
KHQ81_03645	COG3859	Proton-coupled thiamine transporter YuaJ
KHQ81_03655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHQ81_03665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHQ81_03670	COG1242	4 iron, 4 sulfur cluster binding
KHQ81_03680	COG0495	leucyl-tRNA aminoacylation
KHQ81_03685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHQ81_03695	COG0194	GDP metabolic process
KHQ81_03700	COG1758	RNA polymerase activity
KHQ81_03705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHQ81_03715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ81_03725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ81_03735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHQ81_03740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHQ81_03740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHQ81_03755	COG3344	reverse transcriptase
KHQ81_03775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHQ81_03780	COG1162	GTPase activity
KHQ81_03785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHQ81_03790	COG1564	THIamine pyrophosphokinase
KHQ81_03810	COG1302	Protein conserved in bacteria
KHQ81_03815	COG1461	Dihydroxyacetone kinase
KHQ81_03820	COG1307	EDD domain protein, DegV family
KHQ81_03830	COG0511	ligase activity, forming carbon-carbon bonds
KHQ81_03835	COG0439	Biotin carboxylase
KHQ81_03840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHQ81_03855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHQ81_03865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHQ81_03870	COG1028	Short-chain dehydrogenase reductase Sdr
KHQ81_03875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHQ81_03880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHQ81_03885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KHQ81_03885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KHQ81_03890	COG1268	BioY protein
KHQ81_03900	COG1940	carbohydrate kinase activity
KHQ81_03915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHQ81_03925	COG0416	fatty acid biosynthetic process
KHQ81_03935	COG1196	nuclear chromosome segregation
KHQ81_03940	COG0552	protein localization to endoplasmic reticulum
KHQ81_03945	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHQ81_03950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHQ81_03960	COG0393	Putative heavy-metal-binding
KHQ81_03970	COG1132	(ABC) transporter
KHQ81_03975	COG1132	(ABC) transporter
KHQ81_04040	COG2801	Transposase and inactivated derivatives
KHQ81_04050	COG0742	ribosomal rna small subunit methyltransferase
KHQ81_04055	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHQ81_04080	COG0366	Alpha amylase catalytic
KHQ81_04085	COG1266	CAAX protease self-immunity
KHQ81_04090	COG0784	Response regulator, receiver
KHQ81_04090	COG2198	Histidine kinase
KHQ81_04090	COG5002	protein histidine kinase activity
KHQ81_04095	COG2203	Gaf domain
KHQ81_04095	COG3706	GGDEF domain
KHQ81_04095	COG4251	negative regulation of phosphorylation
KHQ81_04095	COG5001	Diguanylate cyclase
KHQ81_04100	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ81_04105	COG1285	pathogenesis
KHQ81_04110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KHQ81_04125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHQ81_04145	COG4974	Belongs to the 'phage' integrase family
KHQ81_04150	COG0756	dUTP diphosphatase activity
KHQ81_04160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHQ81_04165	COG0528	UMP kinase activity
KHQ81_04170	COG0233	cytoplasmic translational termination
KHQ81_04190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHQ81_04195	COG4589	Belongs to the CDS family
KHQ81_04200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KHQ81_04205	COG0750	zinc metalloprotease
KHQ81_04210	COG0442	prolyl-tRNA aminoacylation
KHQ81_04245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHQ81_04250	COG0561	phosphatase activity
KHQ81_04260	COG0406	alpha-ribazole phosphatase activity
KHQ81_04320	COG4471	UPF0298 protein
KHQ81_04325	COG0228	four-way junction DNA binding
KHQ81_04330	COG1837	Belongs to the UPF0109 family
KHQ81_04335	COG0628	permease
KHQ81_04340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHQ81_04350	COG0335	large ribosomal subunit rRNA binding
KHQ81_04360	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHQ81_04375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHQ81_04380	COG0758	DNA mediated transformation
KHQ81_04385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHQ81_04415	COG1363	Peptidase, m42
KHQ81_04440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHQ81_04445	COG0072	phenylalanine-tRNA ligase activity
KHQ81_04445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ81_04465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ81_04470	COG0779	Required for maturation of 30S ribosomal subunits
KHQ81_04475	COG0195	Participates in both transcription termination and antitermination
KHQ81_04480	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHQ81_04495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHQ81_04510	COG0322	excinuclease ABC activity
KHQ81_04515	COG2197	response regulator
KHQ81_04525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KHQ81_04595	COG1305	Transglutaminase-like
KHQ81_04650	COG3620	sequence-specific DNA binding
KHQ81_04690	COG0708	Exodeoxyribonuclease III
KHQ81_04695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHQ81_04695	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ81_04720	COG1012	belongs to the aldehyde dehydrogenase family
KHQ81_04740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHQ81_04740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHQ81_04745	COG2267	carboxylic ester hydrolase activity
KHQ81_04760	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHQ81_04765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHQ81_04770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHQ81_04780	COG0564	pseudouridine synthase activity
KHQ81_04790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHQ81_04795	COG0489	protein tyrosine kinase activity
KHQ81_04800	COG1323	Belongs to the UPF0348 family
KHQ81_04805	COG1399	metal-binding, possibly nucleic acid-binding protein
KHQ81_04815	COG3706	GGDEF domain
KHQ81_04820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHQ81_04825	COG0813	purine-nucleoside phosphorylase activity
KHQ81_04835	COG0612	Peptidase, M16
KHQ81_04840	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHQ81_04845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHQ81_04875	COG2431	L-lysine efflux transmembrane transporter activity
KHQ81_04880	COG1331	Highly conserved protein containing a thioredoxin domain
KHQ81_04930	COG2226	methyltransferase
KHQ81_05000	COG2801	Transposase and inactivated derivatives
KHQ81_05025	COG2205	protein histidine kinase activity
KHQ81_05030	COG0745	RESPONSE REGULATOR receiver
KHQ81_05045	COG1960	acyl-CoA dehydrogenase activity
KHQ81_05050	COG2086	electron transfer activity
KHQ81_05055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KHQ81_05080	COG2081	HI0933 family
KHQ81_05090	COG2226	methyltransferase
KHQ81_05095	COG2832	Protein of unknown function (DUF454)
KHQ81_05100	COG0716	FMN binding
KHQ81_05115	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHQ81_05140	COG0517	IMP dehydrogenase activity
KHQ81_05145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KHQ81_05150	COG0574	Belongs to the PEP-utilizing enzyme family
KHQ81_05150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHQ81_05160	COG3033	Beta-eliminating lyase
KHQ81_05175	COG1607	acyl-coa hydrolase
KHQ81_05180	COG3246	L-lysine catabolic process to acetate
KHQ81_05185	COG0604	alcohol dehydrogenase
KHQ81_05200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHQ81_05205	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHQ81_05210	COG5012	cobalamin binding
KHQ81_05215	COG1024	Enoyl-CoA hydratase
KHQ81_05220	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHQ81_05225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHQ81_05245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHQ81_05250	COG0549	Belongs to the carbamate kinase family
KHQ81_05255	COG3804	dihydrodipicolinate reductase
KHQ81_05265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHQ81_05275	COG5012	cobalamin binding
KHQ81_05285	COG3457	Alanine racemase
KHQ81_05300	COG0312	modulator of DNA gyrase
KHQ81_05305	COG0312	modulator of DNA gyrase
KHQ81_05350	COG2032	superoxide dismutase activity
KHQ81_05355	COG0673	inositol 2-dehydrogenase activity
KHQ81_05360	COG2378	regulation of single-species biofilm formation
KHQ81_05365	COG0551	DNA topoisomerase type I activity
KHQ81_05365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHQ81_05390	COG1217	gtp-binding protein TYPA
KHQ81_05410	COG1695	Transcriptional regulator
KHQ81_05435	COG4656	Part of a membrane complex involved in electron transport
KHQ81_05445	COG4658	electron transport chain
KHQ81_05450	COG4659	FMN binding
KHQ81_05455	COG4660	Part of a membrane complex involved in electron transport
KHQ81_05460	COG4657	Part of a membrane complex involved in electron transport
KHQ81_05510	COG3480	Lon protease (S16) C-terminal proteolytic domain
KHQ81_05515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHQ81_05520	COG0564	pseudouridine synthase activity
KHQ81_05540	COG1702	phosphate starvation-inducible protein PhoH
KHQ81_05545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHQ81_05550	COG0295	cytidine deaminase activity
KHQ81_05570	COG0423	glycine-tRNA ligase activity
KHQ81_05575	COG0358	DNA primase activity
KHQ81_05580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHQ81_05585	COG2384	SAM-dependent methyltransferase
KHQ81_05590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHQ81_05595	COG0513	Belongs to the DEAD box helicase family
KHQ81_05600	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHQ81_05640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHQ81_05645	COG1459	type II secretion system
KHQ81_05655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHQ81_05675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHQ81_05680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHQ81_05685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ81_05690	COG1940	carbohydrate kinase activity
KHQ81_05695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHQ81_05700	COG2801	Transposase and inactivated derivatives
KHQ81_05705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHQ81_05715	COG4537	Required for transformation and DNA binding
KHQ81_05740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHQ81_05755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHQ81_05760	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHQ81_05770	COG1302	Protein conserved in bacteria
KHQ81_05775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHQ81_05780	COG1570	exodeoxyribonuclease VII activity
KHQ81_05785	COG1722	exodeoxyribonuclease VII activity
KHQ81_05795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHQ81_05800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KHQ81_05805	COG0497	DNA recombination
KHQ81_05810	COG0750	zinc metalloprotease
KHQ81_05815	COG0745	RESPONSE REGULATOR receiver
KHQ81_05825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ81_05830	COG0300	oxidoreductase activity
KHQ81_05840	COG0735	belongs to the Fur family
KHQ81_05845	COG4974	Belongs to the 'phage' integrase family
KHQ81_05860	COG0534	Mate efflux family protein
KHQ81_05865	COG0783	Belongs to the Dps family
KHQ81_05875	COG1177	transmembrane transport
KHQ81_05880	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHQ81_05885	COG3842	ATPase activity
KHQ81_05895	COG2226	methyltransferase
KHQ81_05940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHQ81_05945	COG0187	DNA topoisomerase II activity
KHQ81_05950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KHQ81_06000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHQ81_06015	COG2826	transposase and inactivated derivatives, IS30 family
KHQ81_06020	COG2801	Transposase and inactivated derivatives
KHQ81_06045	COG3196	Protein conserved in bacteria
KHQ81_06095	COG0577	efflux transmembrane transporter activity
KHQ81_06095	COG1136	(ABC) transporter
KHQ81_06100	COG1136	(ABC) transporter
KHQ81_06255	COG0582	viral genome integration into host DNA
KHQ81_06360	COG2003	Belongs to the UPF0758 family
KHQ81_06470	COG0789	Transcriptional regulator
KHQ81_06505	COG0588	phosphoglycerate mutase activity
KHQ81_06510	COG1012	belongs to the aldehyde dehydrogenase family
KHQ81_06510	COG1454	alcohol dehydrogenase
KHQ81_06530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHQ81_06555	COG3541	Predicted nucleotidyltransferase
KHQ81_06595	COG1122	ATPase activity
KHQ81_06635	COG0531	amino acid
KHQ81_06650	COG3547	Transposase (IS116 IS110 IS902 family)
KHQ81_06655	COG3850	Histidine kinase
KHQ81_06655	COG5002	protein histidine kinase activity
KHQ81_06660	COG0745	RESPONSE REGULATOR receiver
KHQ81_06680	COG3763	UPF0154 protein
KHQ81_06685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHQ81_06695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHQ81_06700	COG0464	growth
KHQ81_06705	COG0481	GTPase activity
KHQ81_06715	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KHQ81_06720	COG0268	Binds directly to 16S ribosomal RNA
KHQ81_06725	COG1466	dna polymerase III delta subunit
KHQ81_06750	COG2226	methyltransferase
KHQ81_06755	COG0799	negative regulation of ribosome biogenesis
KHQ81_06765	COG1534	Rna-binding protein
KHQ81_06770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHQ81_06775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHQ81_06780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KHQ81_06800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHQ81_06805	COG0572	uridine kinase
KHQ81_06810	COG0826	peptidase U32
KHQ81_06815	COG0826	peptidase U32
KHQ81_06880	COG4122	O-methyltransferase activity
KHQ81_06890	COG1686	Belongs to the peptidase S11 family
KHQ81_06895	COG1846	Transcriptional regulator
KHQ81_06900	COG2814	Major facilitator Superfamily
KHQ81_06905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHQ81_06910	COG3906	Belongs to the UPF0473 family
KHQ81_06920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHQ81_06925	COG0628	permease
KHQ81_06935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHQ81_06940	COG0482	sulfurtransferase activity
KHQ81_06945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHQ81_06990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHQ81_06990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHQ81_06995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHQ81_07000	COG0157	Belongs to the NadC ModD family
KHQ81_07010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHQ81_07015	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHQ81_07020	COG4603	Belongs to the binding-protein-dependent transport system permease family
KHQ81_07025	COG3845	ABC transporter
KHQ81_07030	COG1744	ABC transporter substrate-binding protein PnrA-like
KHQ81_07040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHQ81_07045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHQ81_07050	COG0527	aspartate kinase activity
KHQ81_07055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHQ81_07060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHQ81_07100	COG0196	riboflavin kinase activity
KHQ81_07105	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHQ81_07120	COG1193	negative regulation of DNA recombination
KHQ81_07130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHQ81_07135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHQ81_07140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHQ81_07145	COG0484	heat shock protein binding
KHQ81_07150	COG0443	Heat shock 70 kDa protein
KHQ81_07155	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHQ81_07160	COG1420	regulation of RNA biosynthetic process
KHQ81_07175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHQ81_07200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHQ81_07215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHQ81_07220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHQ81_07225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHQ81_07240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHQ81_07245	COG1122	ATPase activity
KHQ81_07250	COG0390	transport system, permease component
KHQ81_07255	COG0534	Mate efflux family protein
KHQ81_07260	COG1592	Rubrerythrin
KHQ81_07285	COG0301	tRNA thio-modification
KHQ81_07290	COG1104	cysteine desulfurase activity
KHQ81_07300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHQ81_07305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHQ81_07325	COG4869	propanediol catabolic process
KHQ81_07335	COG1605	Chorismate mutase
KHQ81_07335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KHQ81_07345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KHQ81_07350	COG1674	ftsk spoiiie
KHQ81_07355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHQ81_07360	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KHQ81_07365	COG1363	Peptidase, m42
KHQ81_07375	COG0739	heme binding
KHQ81_07380	COG0039	L-malate dehydrogenase activity
KHQ81_07405	COG2801	Transposase and inactivated derivatives
KHQ81_07425	COG0133	tryptophan synthase activity
KHQ81_07460	COG1215	transferase activity, transferring glycosyl groups
KHQ81_07470	COG1086	Polysaccharide biosynthesis protein
KHQ81_07495	COG0330	HflC and HflK could
KHQ81_07510	COG1126	abc transporter atp-binding protein
KHQ81_07515	COG0488	(ABC) transporter
KHQ81_07520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ81_07555	COG0789	Transcriptional regulator
KHQ81_07555	COG4978	Transcriptional regulator
KHQ81_07560	COG1309	transcriptional regulator
KHQ81_07565	COG0534	Mate efflux family protein
KHQ81_07580	COG0367	asparagine synthase
KHQ81_07585	COG1114	Component of the transport system for branched-chain amino acids
KHQ81_07595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHQ81_07600	COG2207	Transcriptional regulator
KHQ81_07600	COG3708	Transcriptional regulator
KHQ81_07650	COG3344	reverse transcriptase
KHQ81_07660	COG1012	belongs to the aldehyde dehydrogenase family
KHQ81_07665	COG1454	alcohol dehydrogenase
KHQ81_07670	COG1309	transcriptional regulator
KHQ81_07680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHQ81_07730	COG1799	cell septum assembly
KHQ81_07735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHQ81_07740	COG1873	PFAM PRC-barrel domain
KHQ81_07745	COG1191	sigma factor activity
KHQ81_07750	COG1191	sigma factor activity
KHQ81_07760	COG2339	peptidase activity
KHQ81_07785	COG2359	stage V sporulation protein S
KHQ81_07790	COG1692	metallophosphoesterase
KHQ81_07805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHQ81_07815	COG3331	DNA recombination
KHQ81_07820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHQ81_07820	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHQ81_07850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHQ81_07865	COG0488	(ABC) transporter
KHQ81_07875	COG1664	Polymer-forming cytoskeletal
KHQ81_07880	COG0789	Transcriptional regulator
KHQ81_07890	COG1234	tRNA 3'-trailer cleavage
KHQ81_07895	COG1132	(ABC) transporter
KHQ81_07910	COG1113	amino acid transport
KHQ81_07940	COG2197	response regulator
KHQ81_07945	COG4585	Histidine kinase
KHQ81_07950	COG2801	Transposase and inactivated derivatives
KHQ81_07965	COG1131	(ABC) transporter
KHQ81_07970	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHQ81_07985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ81_07995	COG1757	Na H antiporter
KHQ81_08010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHQ81_08020	COG0156	8-amino-7-oxononanoate synthase activity
KHQ81_08025	COG1063	alcohol dehydrogenase
KHQ81_08035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHQ81_08040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHQ81_08045	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHQ81_08050	COG0509	glycine decarboxylation via glycine cleavage system
KHQ81_08055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHQ81_08075	COG1307	EDD domain protein, DegV family
KHQ81_08090	COG0170	dolichyl monophosphate biosynthetic process
KHQ81_08100	COG1473	amidohydrolase
KHQ81_08115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHQ81_08120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KHQ81_08130	COG0628	permease
KHQ81_08150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHQ81_08155	COG0124	histidyl-tRNA synthetase
KHQ81_08175	COG2226	methyltransferase
KHQ81_08210	COG3708	Transcriptional regulator
KHQ81_08210	COG2207	Transcriptional regulator
KHQ81_08215	COG2226	methyltransferase
KHQ81_08230	COG1525	nuclease
KHQ81_08230	COG0737	Belongs to the 5'-nucleotidase family
KHQ81_08230	COG4085	toxin activity
KHQ81_08235	COG1228	amidohydrolase
KHQ81_08240	COG0662	Cupin 2, conserved barrel domain protein
KHQ81_08305	COG1490	D-aminoacyl-tRNA deacylase activity
KHQ81_08310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHQ81_08315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHQ81_08320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHQ81_08320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KHQ81_08325	COG2244	polysaccharide biosynthetic process
KHQ81_08330	COG2323	membrane
KHQ81_08410	COG4974	Belongs to the 'phage' integrase family
KHQ81_08490	COG1862	Preprotein translocase
KHQ81_08495	COG0343	queuine tRNA-ribosyltransferase activity
KHQ81_08500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHQ81_08510	COG0632	four-way junction helicase activity
KHQ81_08520	COG2116	formate transmembrane transporter activity
KHQ81_08540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHQ81_08550	COG2868	ribosomal protein
KHQ81_08555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHQ81_08560	COG1994	Peptidase M50
KHQ81_08565	COG0739	heme binding
KHQ81_08575	COG1494	fructose-1,6-bisphosphatase
KHQ81_08585	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHQ81_08585	COG3409	Peptidoglycan-binding domain 1 protein
KHQ81_08605	COG2207	Transcriptional regulator
KHQ81_08630	COG2801	Transposase and inactivated derivatives
KHQ81_08700	COG2003	Belongs to the UPF0758 family
KHQ81_08710	COG2003	Belongs to the UPF0758 family
KHQ81_08720	COG0285	dihydrofolate synthase activity
KHQ81_08725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHQ81_08735	COG0617	tRNA 3'-terminal CCA addition
KHQ81_08740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KHQ81_08745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KHQ81_08750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHQ81_08755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHQ81_08770	COG0776	regulation of translation
KHQ81_08775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHQ81_08785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHQ81_08790	COG1160	GTP binding
KHQ81_08795	COG0539	negative regulation of cytoplasmic translation
KHQ81_08815	COG1187	pseudouridine synthase activity
KHQ81_08820	COG0700	Nucleoside recognition
KHQ81_08825	COG2715	membrane protein required for spore maturation
KHQ81_08830	COG1686	Belongs to the peptidase S11 family
KHQ81_08840	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHQ81_08845	COG0697	spore germination
KHQ81_08855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHQ81_08870	COG2172	sigma factor antagonist activity
KHQ81_08895	COG4555	ABC transporter
KHQ81_08930	COG3142	Participates in the control of copper homeostasis
KHQ81_08970	COG3620	sequence-specific DNA binding
KHQ81_08980	COG2207	Transcriptional regulator
KHQ81_08980	COG3708	Transcriptional regulator
KHQ81_08990	COG4221	oxidoreductase activity
KHQ81_09000	COG2207	Transcriptional regulator
KHQ81_09000	COG3708	Transcriptional regulator
KHQ81_09010	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ81_09015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHQ81_09075	COG3209	COG3209 Rhs family protein
KHQ81_09080	COG1686	Belongs to the peptidase S11 family
KHQ81_09090	COG1686	Belongs to the peptidase S11 family
KHQ81_09110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHQ81_09110	COG0723	plastoquinol--plastocyanin reductase activity
KHQ81_09115	COG1045	serine acetyltransferase
KHQ81_09120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHQ81_09135	COG0671	phosphoesterase, PA-phosphatase related
KHQ81_09155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ81_09160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHQ81_09170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KHQ81_09175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHQ81_09180	COG0772	Belongs to the SEDS family
KHQ81_09185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHQ81_09190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHQ81_09200	COG0768	penicillin binding
KHQ81_09205	COG1597	lipid kinase activity
KHQ81_09230	COG0275	rRNA processing
KHQ81_09235	COG2244	polysaccharide biosynthetic process
KHQ81_09240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHQ81_09250	COG2176	DNA-directed DNA polymerase activity
KHQ81_09265	COG3344	reverse transcriptase
KHQ81_09270	COG0569	domain protein
KHQ81_09290	COG1132	(ABC) transporter
KHQ81_09295	COG1132	(ABC) transporter
KHQ81_09305	COG4608	Belongs to the ABC transporter superfamily
KHQ81_09310	COG0444	Belongs to the ABC transporter superfamily
KHQ81_09315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ81_09320	COG0601	transmembrane transport
KHQ81_09325	COG4166	transmembrane transport
KHQ81_09350	COG1028	Short-chain dehydrogenase reductase Sdr
KHQ81_09355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHQ81_09360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHQ81_09370	COG5001	Diguanylate cyclase
KHQ81_09370	COG3300	MHYT domain
KHQ81_09405	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KHQ81_09445	COG2070	2-Nitropropane dioxygenase
KHQ81_09455	COG0463	Glycosyl transferase, family 2
KHQ81_09460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHQ81_09495	COG0463	Glycosyl transferase, family 2
KHQ81_09505	COG1216	Glycosyl transferase, family 2
KHQ81_09505	COG0438	transferase activity, transferring glycosyl groups
KHQ81_09510	COG1134	teichoic acid transport
KHQ81_09515	COG1682	transport, permease protein
KHQ81_09525	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHQ81_09550	COG0463	Glycosyl transferase, family 2
KHQ81_09575	COG1132	(ABC) transporter
KHQ81_09650	COG1086	Polysaccharide biosynthesis protein
KHQ81_09665	COG0438	transferase activity, transferring glycosyl groups
KHQ81_09675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHQ81_09685	COG0438	transferase activity, transferring glycosyl groups
KHQ81_09690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHQ81_09720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHQ81_09725	COG1215	transferase activity, transferring glycosyl groups
KHQ81_09745	COG1077	Cell shape determining protein MreB Mrl
KHQ81_09755	COG1077	Cell shape determining protein MreB Mrl
KHQ81_09760	COG1077	Cell shape determining protein MreB Mrl
KHQ81_09765	COG1077	Cell shape determining protein MreB Mrl
KHQ81_09790	COG0489	protein tyrosine kinase activity
KHQ81_09795	COG0489	protein tyrosine kinase activity
KHQ81_09805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHQ81_09825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHQ81_09830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KHQ81_09835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHQ81_09840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHQ81_09850	COG1484	DNA-dependent DNA replication
KHQ81_09865	COG0237	dephospho-CoA kinase activity
KHQ81_09870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHQ81_09880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHQ81_09880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHQ81_09885	COG1876	peptidase activity
KHQ81_09895	COG0450	alkyl hydroperoxide reductase
KHQ81_09900	COG2171	N-acyltransferase activity
KHQ81_09915	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHQ81_09930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHQ81_09950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHQ81_09960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHQ81_09965	COG0189	ligase activity
KHQ81_09970	COG2084	Dehydrogenase
KHQ81_09980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHQ81_10015	COG0366	Alpha amylase catalytic
KHQ81_10020	COG3833	ABC-type maltose transport systems, permease component
KHQ81_10025	COG1175	transmembrane transport
KHQ81_10030	COG2182	Extracellular solute-binding protein
KHQ81_10045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHQ81_10050	COG1253	flavin adenine dinucleotide binding
KHQ81_10060	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KHQ81_10075	COG3842	ATPase activity
KHQ81_10090	COG2357	RelA SpoT domain protein
KHQ81_10095	COG4116	CYTH
KHQ81_10100	COG1393	Belongs to the ArsC family
KHQ81_10105	COG0180	Tryptophanyl-tRNA synthetase
KHQ81_10115	COG4608	Belongs to the ABC transporter superfamily
KHQ81_10120	COG0444	Belongs to the ABC transporter superfamily
KHQ81_10125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ81_10130	COG0601	transmembrane transport
KHQ81_10135	COG4166	transmembrane transport
KHQ81_10140	COG0534	Mate efflux family protein
KHQ81_10155	COG0561	phosphatase activity
KHQ81_10180	COG0205	6-phosphofructokinase activity
KHQ81_10185	COG0587	DNA-directed DNA polymerase activity
KHQ81_10190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHQ81_10200	COG3874	Sporulation protein YtfJ
KHQ81_10210	COG0367	asparagine synthase
KHQ81_10215	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KHQ81_10400	COG2183	response to ionizing radiation
KHQ81_10405	COG0436	Aminotransferase
KHQ81_10410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KHQ81_10415	COG2155	Conserved Protein
KHQ81_10420	COG0736	holo-[acyl-carrier-protein] synthase activity
KHQ81_10435	COG0280	phosphate acetyltransferase
KHQ81_10455	COG3051	citrate lyase alpha subunit
KHQ81_10465	COG3052	prosthetic group binding
KHQ81_10495	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KHQ81_10500	COG3681	Belongs to the UPF0597 family
KHQ81_10520	COG3404	Formiminotransferase-cyclodeaminase
KHQ81_10525	COG1228	amidohydrolase
KHQ81_10535	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHQ81_10540	COG2986	histidine ammonia-lyase
KHQ81_10560	COG0251	oxidation-reduction process
KHQ81_10575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KHQ81_10580	COG1660	Displays ATPase and GTPase activities
KHQ81_10590	COG0546	phosphoglycolate phosphatase activity
KHQ81_10595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHQ81_10600	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHQ81_10615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHQ81_10635	COG1649	PFAM Uncharacterised BCR, COG1649
KHQ81_10645	COG1131	(ABC) transporter
KHQ81_10655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHQ81_10670	COG2801	Transposase and inactivated derivatives
KHQ81_10675	COG0297	glycogen (starch) synthase activity
KHQ81_10685	COG0006	proline dipeptidase activity
KHQ81_10690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHQ81_10695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHQ81_10705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ81_10720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHQ81_10735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHQ81_10745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHQ81_10765	COG3557	Belongs to the UPF0374 family
KHQ81_10770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHQ81_10775	COG1393	Belongs to the ArsC family
KHQ81_10780	COG0037	tRNA processing
KHQ81_10805	COG0363	glucosamine-6-phosphate deaminase activity
KHQ81_10810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHQ81_10815	COG2188	Transcriptional regulator
KHQ81_10820	COG2323	membrane
KHQ81_10865	COG0270	DNA (cytosine-5-)-methyltransferase activity
KHQ81_10925	COG2801	Transposase and inactivated derivatives
KHQ81_10975	COG2801	Transposase and inactivated derivatives
KHQ81_10980	COG1131	(ABC) transporter
KHQ81_11010	COG2801	Transposase and inactivated derivatives
KHQ81_11040	COG0488	(ABC) transporter
KHQ81_11050	COG2081	HI0933 family
KHQ81_11070	COG0156	8-amino-7-oxononanoate synthase activity
KHQ81_11075	COG0300	oxidoreductase activity
KHQ81_11115	COG1363	Peptidase, m42
KHQ81_11120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHQ81_11125	COG1368	sulfuric ester hydrolase activity
KHQ81_11135	COG0463	Glycosyl transferase, family 2
KHQ81_11150	COG0667	Aldo Keto reductase
KHQ81_11165	COG1136	(ABC) transporter
KHQ81_11170	COG2205	protein histidine kinase activity
KHQ81_11175	COG0745	RESPONSE REGULATOR receiver
KHQ81_11180	COG0012	GTP binding
KHQ81_11185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHQ81_11190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ81_11195	COG0084	hydrolase, TatD family'
KHQ81_11200	COG1272	protein, Hemolysin III
KHQ81_11220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHQ81_11225	COG2378	regulation of single-species biofilm formation
KHQ81_11230	COG2267	carboxylic ester hydrolase activity
KHQ81_11235	COG1132	(ABC) transporter
KHQ81_11245	COG0393	Putative heavy-metal-binding
KHQ81_11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHQ81_11265	COG1126	abc transporter atp-binding protein
KHQ81_11270	COG0765	amino acid transport
KHQ81_11295	COG2356	endonuclease I
KHQ81_11320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KHQ81_11325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHQ81_11335	COG0494	nUDIX hydrolase
KHQ81_11350	COG2814	Major facilitator Superfamily
KHQ81_11425	COG1247	-acetyltransferase
KHQ81_11455	COG1131	(ABC) transporter
KHQ81_11490	COG1131	(ABC) transporter
KHQ81_11495	COG0312	modulator of DNA gyrase
KHQ81_11500	COG0312	modulator of DNA gyrase
KHQ81_11510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHQ81_11535	COG2135	peptidase activity
KHQ81_11555	COG2801	Transposase and inactivated derivatives
KHQ81_11580	COG0519	Catalyzes the synthesis of GMP from XMP
KHQ81_11585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHQ81_11595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHQ81_11620	COG3634	alkyl hydroperoxide reductase activity
KHQ81_11635	COG1136	(ABC) transporter
KHQ81_11635	COG0577	efflux transmembrane transporter activity
KHQ81_11670	COG1136	(ABC) transporter
KHQ81_11675	COG0577	efflux transmembrane transporter activity
KHQ81_11680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHQ81_11685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHQ81_11715	COG3344	reverse transcriptase
KHQ81_11770	COG1131	(ABC) transporter
KHQ81_11775	COG1725	Transcriptional regulator
KHQ81_11790	COG0789	Transcriptional regulator
KHQ81_11805	COG3620	sequence-specific DNA binding
KHQ81_11845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KHQ81_11855	COG3447	MASE1 domain protein
KHQ81_11855	COG5002	protein histidine kinase activity
KHQ81_11855	COG5001	Diguanylate cyclase
KHQ81_11865	COG0709	Synthesizes selenophosphate from selenide and ATP
KHQ81_11870	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KHQ81_11885	COG1720	tRNA m6t6A37 methyltransferase activity
KHQ81_11900	COG0513	Belongs to the DEAD box helicase family
KHQ81_11910	COG3437	response regulator, receiver
KHQ81_11915	COG0095	Lipoate-protein ligase
KHQ81_11930	COG1846	Transcriptional regulator
KHQ81_11950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHQ81_11970	COG0167	dihydroorotate dehydrogenase activity
KHQ81_11975	COG0543	2 iron, 2 sulfur cluster binding
KHQ81_11980	COG0284	orotidine-5'-phosphate decarboxylase activity
KHQ81_12025	COG1944	ATP diphosphatase activity
KHQ81_12030	COG1278	Cold shock
KHQ81_12040	COG2132	Multicopper oxidase
KHQ81_12050	COG2801	Transposase and inactivated derivatives
KHQ81_12055	COG1695	Transcriptional regulator
KHQ81_12075	COG1120	ATPase activity
KHQ81_12080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHQ81_12085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHQ81_12145	COG2801	Transposase and inactivated derivatives
KHQ81_12165	COG5002	protein histidine kinase activity
KHQ81_12170	COG0745	RESPONSE REGULATOR receiver
KHQ81_12180	COG1136	(ABC) transporter
KHQ81_12190	COG1937	Protein conserved in bacteria
KHQ81_12195	COG3344	reverse transcriptase
KHQ81_12220	COG2378	regulation of single-species biofilm formation
KHQ81_12225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHQ81_12245	COG1609	Transcriptional regulator
KHQ81_12250	COG3833	ABC-type maltose transport systems, permease component
KHQ81_12255	COG1175	transmembrane transport
KHQ81_12275	COG0366	Alpha amylase catalytic
KHQ81_12285	COG1523	belongs to the glycosyl hydrolase 13 family
KHQ81_12290	COG0058	SHG alpha-glucan phosphorylase activity
KHQ81_12295	COG0366	Alpha amylase catalytic
KHQ81_12300	COG0366	Alpha amylase catalytic
KHQ81_12315	COG2732	(Barnase) inhibitor
KHQ81_12330	COG2186	Transcriptional regulator
KHQ81_12345	COG1073	alpha beta
KHQ81_12350	COG0456	acetyltransferase
KHQ81_12360	COG1151	hydroxylamine reductase activity
KHQ81_12370	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KHQ81_12375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KHQ81_12400	COG0577	efflux transmembrane transporter activity
KHQ81_12405	COG1136	(ABC) transporter
KHQ81_12410	COG2205	protein histidine kinase activity
KHQ81_12415	COG0745	RESPONSE REGULATOR receiver
KHQ81_12450	COG1309	transcriptional regulator
KHQ81_12455	COG2801	Transposase and inactivated derivatives
KHQ81_12485	COG0436	Aminotransferase
KHQ81_12580	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KHQ81_12585	COG1309	transcriptional regulator
KHQ81_12610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHQ81_12630	COG1396	sequence-specific DNA binding
KHQ81_12675	COG2015	COG2015, Alkyl sulfatase and related hydrolases
KHQ81_12690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KHQ81_12700	COG1840	ABC-type Fe3 transport system, periplasmic component
KHQ81_12705	COG2323	membrane
KHQ81_12710	COG1760	l-serine dehydratase
KHQ81_12725	COG0556	nucleotide-excision repair
KHQ81_12730	COG0793	Belongs to the peptidase S41A family
KHQ81_12730	COG3409	Peptidoglycan-binding domain 1 protein
KHQ81_12735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHQ81_12740	COG0653	protein targeting
KHQ81_12750	COG0419	ATPase involved in DNA repair
KHQ81_12755	COG0420	3'-5' exonuclease activity
KHQ81_12760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHQ81_12770	COG1040	competence protein
KHQ81_12775	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHQ81_13040	COG3645	SOS response
KHQ81_13040	COG3646	Phage regulatory protein
KHQ81_13055	COG1396	sequence-specific DNA binding
KHQ81_13075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHQ81_13110	COG1739	Uncharacterized protein family UPF0029
KHQ81_13115	COG1609	Transcriptional regulator
KHQ81_13145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHQ81_13150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHQ81_13160	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHQ81_13170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHQ81_13195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHQ81_13200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHQ81_13205	COG0698	ribose 5-phosphate isomerase
KHQ81_13230	COG0740	serine-type endopeptidase activity
KHQ81_13260	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHQ81_13265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHQ81_13275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHQ81_13300	COG0596	Alpha beta hydrolase
KHQ81_13360	COG1132	(ABC) transporter
KHQ81_13365	COG1132	(ABC) transporter
KHQ81_13400	COG2314	TM2 domain
KHQ81_13465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHQ81_13470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHQ81_13475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHQ81_13515	COG0704	Plays a role in the regulation of phosphate uptake
KHQ81_13520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHQ81_13530	COG0573	inorganic phosphate transmembrane transporter activity
KHQ81_13535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHQ81_13540	COG1283	sodium-dependent phosphate transmembrane transporter activity
KHQ81_13550	COG5002	protein histidine kinase activity
KHQ81_13555	COG0745	RESPONSE REGULATOR receiver
KHQ81_13575	COG1435	thymidine kinase activity
KHQ81_13585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHQ81_13600	COG0281	malic enzyme
KHQ81_13605	COG1027	Aspartate ammonia-lyase
KHQ81_13635	COG1252	NADH dehydrogenase
KHQ81_13645	COG2252	PERMEase
KHQ81_13650	COG1218	3'(2'),5'-bisphosphate nucleotidase
KHQ81_13655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHQ81_13670	COG1649	PFAM Uncharacterised BCR, COG1649
KHQ81_13685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHQ81_13690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHQ81_13695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHQ81_13715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHQ81_13720	COG0445	tRNA wobble uridine modification
KHQ81_13735	COG0504	CTP synthase activity
KHQ81_13745	COG0018	arginyl-trna synthetase
KHQ81_13755	COG1132	(ABC) transporter
KHQ81_13760	COG4481	Protein conserved in bacteria
KHQ81_13765	COG1475	DNA binding
KHQ81_13770	COG1192	Involved in chromosome partitioning
KHQ81_13785	COG0357	Ribosomal RNA small subunit methyltransferase G
KHQ81_13790	COG0445	tRNA wobble uridine modification
KHQ81_13795	COG0017	Asparaginyl-tRNA synthetase
KHQ81_13805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHQ81_13815	COG0706	membrane insertase activity
KHQ81_13820	COG0594	ribonuclease P activity
KHQ81_13825	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KHQ81_13830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHQ81_13845	COG2501	S4 domain
KHQ81_13850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHQ81_13855	COG0187	DNA topoisomerase II activity
KHQ81_13865	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KHQ81_13870	COG2826	transposase and inactivated derivatives, IS30 family
KHQ81_13880	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHQ81_13885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHQ81_13890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHQ81_13895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHQ81_13910	COG0284	orotidine-5'-phosphate decarboxylase activity
KHQ81_13940	COG0667	Aldo Keto reductase
KHQ81_13945	COG1187	pseudouridine synthase activity
KHQ81_13955	COG0312	modulator of DNA gyrase
KHQ81_13990	COG1309	transcriptional regulator
KHQ81_14000	COG3546	catalase activity
KHQ81_14020	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHQ81_14025	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KHQ81_14050	COG0745	RESPONSE REGULATOR receiver
KHQ81_14055	COG5002	protein histidine kinase activity
KHQ81_14065	COG0826	peptidase U32
KHQ81_14070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHQ81_14080	COG0163	prenyltransferase activity
KHQ81_14085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KHQ81_14090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KHQ81_14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHQ81_14110	COG1131	(ABC) transporter
KHQ81_14120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHQ81_14125	COG3344	reverse transcriptase
KHQ81_14130	COG0537	adenosine 5'-monophosphoramidase activity
KHQ81_14140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHQ81_14150	COG3773	Cell wall hydrolase
KHQ81_14155	COG1078	dGTPase activity
KHQ81_14180	COG0116	Belongs to the methyltransferase superfamily
KHQ81_14200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHQ81_14215	COG2088	sporulation resulting in formation of a cellular spore
KHQ81_14230	COG0193	aminoacyl-tRNA hydrolase activity
KHQ81_14235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHQ81_14240	COG2002	toxin-antitoxin pair type II binding
KHQ81_14245	COG0561	phosphatase activity
KHQ81_14250	COG2244	polysaccharide biosynthetic process
KHQ81_14255	COG0530	calcium, potassium:sodium antiporter activity
KHQ81_14275	COG0826	peptidase U32
KHQ81_14285	COG1695	Transcriptional regulator
KHQ81_14335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHQ81_14365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHQ81_14365	COG0037	tRNA processing
KHQ81_14370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHQ81_14375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHQ81_14380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHQ81_14415	COG2801	Transposase and inactivated derivatives
KHQ81_14460	COG2270	Major facilitator Superfamily
KHQ81_14470	COG0622	Phosphoesterase
KHQ81_14475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHQ81_14485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHQ81_14495	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHQ81_14500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHQ81_14505	COG1494	fructose-1,6-bisphosphatase
KHQ81_14515	COG0564	pseudouridine synthase activity
KHQ81_14520	COG0116	Belongs to the methyltransferase superfamily
KHQ81_14520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHQ81_14530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHQ81_14535	COG0542	response to heat
KHQ81_14540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHQ81_14545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHQ81_14555	COG0215	cysteine-tRNA ligase activity
KHQ81_14560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHQ81_14565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ81_14570	COG1191	sigma factor activity
KHQ81_14575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ81_14585	COG0250	Participates in transcription elongation, termination and antitermination
KHQ81_14595	COG0081	regulation of translation
KHQ81_14605	COG0222	ribosome binding
KHQ81_14610	COG2813	Specifically methylates the guanine in position
KHQ81_14615	COG0085	RNA polymerase activity
KHQ81_14620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHQ81_14625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHQ81_14630	COG0049	tRNA binding
KHQ81_14635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHQ81_14640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHQ81_14645	COG1193	negative regulation of DNA recombination
KHQ81_14650	COG0051	transcription antitermination factor activity, RNA binding
KHQ81_14655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHQ81_14660	COG0088	Forms part of the polypeptide exit tunnel
KHQ81_14665	COG0089	rRNA binding
KHQ81_14670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHQ81_14675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHQ81_14680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHQ81_14685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHQ81_14690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHQ81_14695	COG0255	Belongs to the universal ribosomal protein uL29 family
KHQ81_14700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHQ81_14720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHQ81_14725	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHQ81_14730	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHQ81_14735	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHQ81_14745	COG1841	ribosomal large subunit assembly
KHQ81_14750	COG0200	Binds to the 23S rRNA
KHQ81_14755	COG0201	protein transport
KHQ81_14760	COG0563	adenylate kinase activity
KHQ81_14765	COG0024	Methionine aminopeptidase
KHQ81_14770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHQ81_14775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHQ81_14780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHQ81_14785	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHQ81_14790	COG0202	RNA polymerase activity
KHQ81_14815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHQ81_14820	COG0101	tRNA pseudouridine synthase activity
KHQ81_14845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ81_14855	COG0039	L-malate dehydrogenase activity
KHQ81_14860	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KHQ81_14865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHQ81_14870	COG0470	DNA polymerase III
KHQ81_14875	COG1774	PSP1 C-terminal conserved region
KHQ81_14880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KHQ81_14910	COG0149	triose-phosphate isomerase activity
KHQ81_14920	COG4974	Belongs to the 'phage' integrase family
KHQ81_14955	COG2801	Transposase and inactivated derivatives
KHQ81_15010	COG2801	Transposase and inactivated derivatives
KHQ81_15025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHQ81_15030	COG0009	L-threonylcarbamoyladenylate synthase
KHQ81_15050	COG1982	Orn Lys Arg decarboxylase major
KHQ81_15055	COG0010	Belongs to the arginase family
KHQ81_15080	COG1285	pathogenesis
KHQ81_15085	COG2153	protein acetylation
KHQ81_15090	COG4555	ABC transporter
KHQ81_15095	COG1668	transmembrane transport
KHQ81_15100	COG1610	YqeY-like protein
KHQ81_15110	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHQ81_15115	COG1115	amino acid carrier protein
KHQ81_15120	COG1546	Belongs to the CinA family
KHQ81_15120	COG1058	Belongs to the CinA family
KHQ81_15130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHQ81_15140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHQ81_15180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHQ81_15180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHQ81_15225	COG1131	(ABC) transporter
KHQ81_15515	COG4962	Type ii secretion system protein e