locus-tag	class	description
KHQ89_00010	COG1780	Probably involved in ribonucleotide reductase function
KHQ89_00015	COG5002	protein histidine kinase activity
KHQ89_00025	COG0704	Plays a role in the regulation of phosphate uptake
KHQ89_00035	COG0581	inorganic phosphate transmembrane transporter activity
KHQ89_00055	COG0598	Magnesium transport protein CorA
KHQ89_00070	COG2226	methyltransferase
KHQ89_00075	COG4496	protein, YerC YecD
KHQ89_00080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHQ89_00085	COG0765	amino acid transport
KHQ89_00105	COG1136	(ABC) transporter
KHQ89_00110	COG1012	belongs to the aldehyde dehydrogenase family
KHQ89_00115	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KHQ89_00120	COG5001	Diguanylate cyclase
KHQ89_00120	COG3300	MHYT domain
KHQ89_00135	COG0745	RESPONSE REGULATOR receiver
KHQ89_00165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHQ89_00170	COG2217	Heavy metal translocating P-type atpase
KHQ89_00195	COG2217	Heavy metal translocating P-type atpase
KHQ89_00200	COG0640	Transcriptional regulator
KHQ89_00210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ89_00215	COG0656	L-ascorbic acid biosynthetic process
KHQ89_00265	COG0513	Belongs to the DEAD box helicase family
KHQ89_00290	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KHQ89_00300	COG1805	sodium ion transport
KHQ89_00320	COG2304	oxidoreductase activity
KHQ89_00325	COG0745	RESPONSE REGULATOR receiver
KHQ89_00330	COG2205	protein histidine kinase activity
KHQ89_00330	COG2770	Histidine kinase
KHQ89_00365	COG1597	lipid kinase activity
KHQ89_00415	COG1982	Orn Lys Arg decarboxylase major
KHQ89_00420	COG0668	transmembrane transport
KHQ89_00425	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KHQ89_00430	COG0367	asparagine synthase
KHQ89_00435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHQ89_00440	COG2203	Gaf domain
KHQ89_00440	COG2199	diguanylate cyclase activity
KHQ89_00450	COG2252	PERMEase
KHQ89_00465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHQ89_00465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHQ89_00465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHQ89_00485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ89_00495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHQ89_00505	COG2890	protein-(glutamine-N5) methyltransferase activity
KHQ89_00510	COG1774	PSP1 C-terminal conserved region
KHQ89_00515	COG0470	DNA polymerase III
KHQ89_00520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHQ89_00525	COG0101	tRNA pseudouridine synthase activity
KHQ89_00530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHQ89_00550	COG0492	ferredoxin-NADP+ reductase activity
KHQ89_00575	COG2356	endonuclease I
KHQ89_00580	COG0203	ribosomal protein L17
KHQ89_00585	COG0202	RNA polymerase activity
KHQ89_00590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHQ89_00595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHQ89_00600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHQ89_00605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHQ89_00610	COG0024	Methionine aminopeptidase
KHQ89_00620	COG0201	protein transport
KHQ89_00625	COG0200	Binds to the 23S rRNA
KHQ89_00630	COG1841	ribosomal large subunit assembly
KHQ89_00635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHQ89_00645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHQ89_00650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHQ89_00660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHQ89_00665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHQ89_00670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHQ89_00675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHQ89_00680	COG0255	Belongs to the universal ribosomal protein uL29 family
KHQ89_00685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHQ89_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHQ89_00700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHQ89_00705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHQ89_00710	COG0089	rRNA binding
KHQ89_00715	COG0088	Forms part of the polypeptide exit tunnel
KHQ89_00720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHQ89_00725	COG0051	transcription antitermination factor activity, RNA binding
KHQ89_00750	COG1307	EDD domain protein, DegV family
KHQ89_00850	COG1475	DNA binding
KHQ89_00855	COG1192	Involved in chromosome partitioning
KHQ89_00860	COG0357	Ribosomal RNA small subunit methyltransferase G
KHQ89_00865	COG0445	tRNA wobble uridine modification
KHQ89_00885	COG0590	tRNA wobble adenosine to inosine editing
KHQ89_00890	COG1435	thymidine kinase activity
KHQ89_00895	COG0254	rRNA binding
KHQ89_00915	COG2878	Part of a membrane complex involved in electron transport
KHQ89_00925	COG4657	Part of a membrane complex involved in electron transport
KHQ89_00930	COG4660	Part of a membrane complex involved in electron transport
KHQ89_00955	COG4656	Part of a membrane complex involved in electron transport
KHQ89_00960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHQ89_00965	COG0217	transcriptional regulatory protein
KHQ89_00975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHQ89_00980	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KHQ89_00985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHQ89_00995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHQ89_01015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHQ89_01020	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHQ89_01025	COG2801	Transposase and inactivated derivatives
KHQ89_01030	COG2801	Transposase and inactivated derivatives
KHQ89_01040	COG2211	Major facilitator Superfamily
KHQ89_01045	COG1472	Belongs to the glycosyl hydrolase 3 family
KHQ89_01055	COG3345	alpha-galactosidase
KHQ89_01060	COG0366	Alpha amylase catalytic
KHQ89_01070	COG0037	tRNA processing
KHQ89_01075	COG0037	tRNA processing
KHQ89_01075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHQ89_01085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHQ89_01135	COG3343	RNA polymerase activity
KHQ89_01145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHQ89_01150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHQ89_01155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHQ89_01160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHQ89_01165	COG1285	pathogenesis
KHQ89_01170	COG0037	tRNA processing
KHQ89_01175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ89_01180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ89_01185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KHQ89_01185	COG0519	Catalyzes the synthesis of GMP from XMP
KHQ89_01195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHQ89_01200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHQ89_01205	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHQ89_01210	COG1609	Transcriptional regulator
KHQ89_01240	COG0395	ABC-type sugar transport system, permease component
KHQ89_01295	COG0594	ribonuclease P activity
KHQ89_01300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KHQ89_01310	COG0592	DNA-directed DNA polymerase activity
KHQ89_01320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHQ89_01330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHQ89_01335	COG0628	permease
KHQ89_01340	COG4894	glucomannan catabolic process
KHQ89_01360	COG1368	sulfuric ester hydrolase activity
KHQ89_01370	COG1968	undecaprenyl-diphosphatase activity
KHQ89_01390	COG0745	RESPONSE REGULATOR receiver
KHQ89_01395	COG2205	protein histidine kinase activity
KHQ89_01395	COG2770	Histidine kinase
KHQ89_01405	COG0537	adenosine 5'-monophosphoramidase activity
KHQ89_01410	COG4869	propanediol catabolic process
KHQ89_01415	COG1078	dGTPase activity
KHQ89_01420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHQ89_01425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHQ89_01430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHQ89_01435	COG2088	sporulation resulting in formation of a cellular spore
KHQ89_01440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHQ89_01445	COG0193	aminoacyl-tRNA hydrolase activity
KHQ89_01450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHQ89_01465	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHQ89_01485	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHQ89_01485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHQ89_01495	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHQ89_01505	COG1307	EDD domain protein, DegV family
KHQ89_01510	COG0539	negative regulation of cytoplasmic translation
KHQ89_01520	COG0802	atpase or kinase
KHQ89_01525	COG1214	PFAM Peptidase M22, glycoprotease
KHQ89_01535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHQ89_01560	COG2135	peptidase activity
KHQ89_01565	COG1464	Belongs to the NlpA lipoprotein family
KHQ89_01575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHQ89_01590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ89_01610	COG0534	Mate efflux family protein
KHQ89_01615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHQ89_01650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHQ89_01655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHQ89_01665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHQ89_01670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHQ89_01675	COG0546	phosphoglycolate phosphatase activity
KHQ89_01680	COG0492	ferredoxin-NADP+ reductase activity
KHQ89_01690	COG0736	holo-[acyl-carrier-protein] synthase activity
KHQ89_01720	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KHQ89_01725	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KHQ89_01750	COG0415	Belongs to the DNA photolyase family
KHQ89_01765	COG3177	Filamentation induced by cAMP protein fic
KHQ89_01785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHQ89_01790	COG4221	oxidoreductase activity
KHQ89_01795	COG1393	Belongs to the ArsC family
KHQ89_01855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHQ89_01865	COG0514	ATP-dependent DNA helicase (RecQ)
KHQ89_01870	COG0514	ATP-dependent DNA helicase (RecQ)
KHQ89_01875	COG0583	DNA-binding transcription factor activity
KHQ89_01920	COG0534	Mate efflux family protein
KHQ89_01960	COG1309	transcriptional regulator
KHQ89_01970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHQ89_01985	COG1063	alcohol dehydrogenase
KHQ89_01990	COG4399	Belongs to the UPF0754 family
KHQ89_02030	COG2081	HI0933 family
KHQ89_02040	COG2188	Transcriptional regulator
KHQ89_02055	COG0395	ABC-type sugar transport system, permease component
KHQ89_02060	COG1653	transport
KHQ89_02065	COG1175	transmembrane transport
KHQ89_02100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ89_02115	COG1253	flavin adenine dinucleotide binding
KHQ89_02120	COG4753	response regulator
KHQ89_02120	COG2207	Transcriptional regulator
KHQ89_02135	COG2972	Histidine kinase
KHQ89_02145	COG1879	ABC-type sugar transport system periplasmic component
KHQ89_02150	COG1879	ABC-type sugar transport system periplasmic component
KHQ89_02160	COG4211	Belongs to the binding-protein-dependent transport system permease family
KHQ89_02195	COG0395	ABC-type sugar transport system, permease component
KHQ89_02225	COG1175	transmembrane transport
KHQ89_02230	COG0395	ABC-type sugar transport system, permease component
KHQ89_02270	COG0366	Alpha amylase catalytic
KHQ89_02285	COG3459	Glycosyltransferase 36 associated
KHQ89_02290	COG1131	(ABC) transporter
KHQ89_02300	COG1609	Transcriptional regulator
KHQ89_02315	COG3507	Belongs to the glycosyl hydrolase 43 family
KHQ89_02325	COG1175	transmembrane transport
KHQ89_02330	COG0395	ABC-type sugar transport system, permease component
KHQ89_02345	COG0737	Belongs to the 5'-nucleotidase family
KHQ89_02360	COG0745	RESPONSE REGULATOR receiver
KHQ89_02365	COG5002	protein histidine kinase activity
KHQ89_02370	COG0577	efflux transmembrane transporter activity
KHQ89_02370	COG1136	(ABC) transporter
KHQ89_02380	COG2199	diguanylate cyclase activity
KHQ89_02395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ89_02415	COG0039	L-malate dehydrogenase activity
KHQ89_02420	COG0501	Belongs to the peptidase M48B family
KHQ89_02445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHQ89_02450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KHQ89_02465	COG3271	cysteine-type peptidase activity
KHQ89_02465	COG2274	protein secretion by the type I secretion system
KHQ89_02470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHQ89_02500	COG0215	cysteine-tRNA ligase activity
KHQ89_02505	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHQ89_02510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHQ89_02525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ89_02540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHQ89_02550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHQ89_02555	COG0081	regulation of translation
KHQ89_02565	COG0222	ribosome binding
KHQ89_02570	COG2813	Specifically methylates the guanine in position
KHQ89_02585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHQ89_02600	COG0300	oxidoreductase activity
KHQ89_02610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHQ89_02615	COG0049	tRNA binding
KHQ89_02620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHQ89_02625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHQ89_02630	COG0084	hydrolase, TatD family'
KHQ89_02635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ89_02640	COG1546	Belongs to the CinA family
KHQ89_02640	COG1058	Belongs to the CinA family
KHQ89_02645	COG0360	Binds together with S18 to 16S ribosomal RNA
KHQ89_02655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHQ89_02660	COG0359	binds to the 23S rRNA
KHQ89_02660	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KHQ89_02665	COG0305	Participates in initiation and elongation during chromosome replication
KHQ89_02670	COG0305	Participates in initiation and elongation during chromosome replication
KHQ89_02680	COG0783	Belongs to the Dps family
KHQ89_02685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHQ89_02695	COG0009	L-threonylcarbamoyladenylate synthase
KHQ89_02715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHQ89_02745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHQ89_02750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHQ89_02755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHQ89_02760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHQ89_02765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHQ89_02770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHQ89_02785	COG1739	Uncharacterized protein family UPF0029
KHQ89_02810	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KHQ89_02815	COG0579	oxidoreductase
KHQ89_02820	COG0492	ferredoxin-NADP+ reductase activity
KHQ89_02830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHQ89_02855	COG0617	tRNA 3'-terminal CCA addition
KHQ89_02860	COG3481	metal-dependent phosphohydrolase, HD sub domain
KHQ89_02885	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHQ89_02890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHQ89_02900	COG1307	EDD domain protein, DegV family
KHQ89_02910	COG1695	Transcriptional regulator
KHQ89_02930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KHQ89_02940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHQ89_02945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHQ89_03005	COG1609	Transcriptional regulator
KHQ89_03020	COG3833	ABC-type maltose transport systems, permease component
KHQ89_03035	COG0640	Transcriptional regulator
KHQ89_03040	COG2217	Heavy metal translocating P-type atpase
KHQ89_03050	COG0416	fatty acid biosynthetic process
KHQ89_03065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHQ89_03070	COG0673	inositol 2-dehydrogenase activity
KHQ89_03085	COG1132	(ABC) transporter
KHQ89_03090	COG1132	(ABC) transporter
KHQ89_03100	COG0716	FMN binding
KHQ89_03105	COG0587	DNA-directed DNA polymerase activity
KHQ89_03125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHQ89_03145	COG0205	6-phosphofructokinase activity
KHQ89_03150	COG0205	6-phosphofructokinase activity
KHQ89_03155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHQ89_03155	COG0574	Belongs to the PEP-utilizing enzyme family
KHQ89_03165	COG0556	nucleotide-excision repair
KHQ89_03200	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHQ89_03220	COG1132	(ABC) transporter
KHQ89_03225	COG1132	(ABC) transporter
KHQ89_03240	COG2239	Acts as a magnesium transporter
KHQ89_03245	COG2239	Acts as a magnesium transporter
KHQ89_03255	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KHQ89_03260	COG1760	l-serine dehydratase
KHQ89_03265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ89_03270	COG1278	Cold shock
KHQ89_03280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHQ89_03290	COG1045	serine acetyltransferase
KHQ89_03305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHQ89_03310	COG4605	iron ion homeostasis
KHQ89_03315	COG4604	ABC transporter, ATP-binding protein
KHQ89_03320	COG4607	ABC-type enterochelin transport system periplasmic component
KHQ89_03340	COG1702	phosphate starvation-inducible protein PhoH
KHQ89_03345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHQ89_03350	COG0295	cytidine deaminase activity
KHQ89_03355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHQ89_03365	COG0423	glycine-tRNA ligase activity
KHQ89_03370	COG0358	DNA primase activity
KHQ89_03375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHQ89_03400	COG0561	phosphatase activity
KHQ89_03415	COG1674	ftsk spoiiie
KHQ89_03420	COG0681	Belongs to the peptidase S26 family
KHQ89_03425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHQ89_03430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHQ89_03435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHQ89_03440	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHQ89_03445	COG0552	protein localization to endoplasmic reticulum
KHQ89_03455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHQ89_03465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHQ89_03470	COG0237	dephospho-CoA kinase activity
KHQ89_03480	COG1484	DNA-dependent DNA replication
KHQ89_03490	COG4152	abc transporter atp-binding protein
KHQ89_03500	COG1131	(ABC) transporter
KHQ89_03520	COG0489	protein tyrosine kinase activity
KHQ89_03525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHQ89_03530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHQ89_03540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHQ89_03545	COG3547	Transposase (IS116 IS110 IS902 family)
KHQ89_03555	COG2267	carboxylic ester hydrolase activity
KHQ89_03560	COG2084	Dehydrogenase
KHQ89_03605	COG0708	Exodeoxyribonuclease III
KHQ89_03610	COG2801	Transposase and inactivated derivatives
KHQ89_03620	COG0154	amidase activity
KHQ89_03635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHQ89_03650	COG0148	phosphopyruvate hydratase activity
KHQ89_03655	COG3588	fructose-bisphosphate aldolase
KHQ89_03670	COG0439	Biotin carboxylase
KHQ89_03675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHQ89_03685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHQ89_03695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHQ89_03700	COG1028	Short-chain dehydrogenase reductase Sdr
KHQ89_03715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KHQ89_03715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KHQ89_03720	COG0557	exoribonuclease II activity
KHQ89_03725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHQ89_03750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHQ89_03755	COG3906	Belongs to the UPF0473 family
KHQ89_03775	COG4122	O-methyltransferase activity
KHQ89_03785	COG0826	peptidase U32
KHQ89_03805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHQ89_03810	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KHQ89_03825	COG0799	negative regulation of ribosome biogenesis
KHQ89_03830	COG2264	protein methyltransferase activity
KHQ89_03855	COG1466	dna polymerase III delta subunit
KHQ89_03865	COG0268	Binds directly to 16S ribosomal RNA
KHQ89_03875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHQ89_03885	COG1136	(ABC) transporter
KHQ89_03895	COG4372	Transposase
KHQ89_03895	COG1418	mRNA catabolic process
KHQ89_03900	COG1692	metallophosphoesterase
KHQ89_03920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHQ89_03925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHQ89_03930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHQ89_03935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHQ89_03940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHQ89_03945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHQ89_03960	COG1187	pseudouridine synthase activity
KHQ89_03965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHQ89_03975	COG1160	GTP binding
KHQ89_03980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHQ89_03985	COG0776	regulation of translation
KHQ89_03995	COG1266	CAAX protease self-immunity
KHQ89_04000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHQ89_04035	COG1902	pentaerythritol trinitrate reductase activity
KHQ89_04040	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHQ89_04120	COG4176	ABC-type proline glycine betaine transport system permease component
KHQ89_04125	COG0517	IMP dehydrogenase activity
KHQ89_04125	COG4175	Glycine betaine
KHQ89_04135	COG1694	Mazg nucleotide pyrophosphohydrolase
KHQ89_04140	COG0133	tryptophan synthase activity
KHQ89_04170	COG1609	Transcriptional regulator
KHQ89_04185	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHQ89_04240	COG1695	Transcriptional regulator
KHQ89_04250	COG0494	nUDIX hydrolase
KHQ89_04265	COG0488	(ABC) transporter
KHQ89_04275	COG2217	Heavy metal translocating P-type atpase
KHQ89_04305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ89_04315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHQ89_04320	COG0588	phosphoglycerate mutase activity
KHQ89_04325	COG0588	phosphoglycerate mutase activity
KHQ89_04330	COG1420	regulation of RNA biosynthetic process
KHQ89_04335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHQ89_04340	COG0443	Heat shock 70 kDa protein
KHQ89_04350	COG0095	Lipoate-protein ligase
KHQ89_04365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHQ89_04370	COG0275	rRNA processing
KHQ89_04375	COG1803	Methylglyoxal synthase
KHQ89_04385	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHQ89_04395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHQ89_04395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHQ89_04400	COG0482	sulfurtransferase activity
KHQ89_04405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHQ89_04410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHQ89_04420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHQ89_04425	COG0297	glycogen (starch) synthase activity
KHQ89_04440	COG0686	Belongs to the AlaDH PNT family
KHQ89_04465	COG0077	Prephenate dehydratase
KHQ89_04465	COG1605	Chorismate mutase
KHQ89_04480	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHQ89_04485	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ89_04525	COG1132	(ABC) transporter
KHQ89_04550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ89_04600	COG0564	pseudouridine synthase activity
KHQ89_04635	COG0275	rRNA processing
KHQ89_04645	COG3590	peptidase
KHQ89_04650	COG3590	peptidase
KHQ89_04685	COG0546	phosphoglycolate phosphatase activity
KHQ89_04690	COG1136	(ABC) transporter
KHQ89_04690	COG0577	efflux transmembrane transporter activity
KHQ89_04695	COG1136	(ABC) transporter
KHQ89_04695	COG0577	efflux transmembrane transporter activity
KHQ89_04700	COG0778	Nitroreductase
KHQ89_04710	COG1194	a g-specific adenine glycosylase
KHQ89_04720	COG0789	Transcriptional regulator
KHQ89_04730	COG0343	queuine tRNA-ribosyltransferase activity
KHQ89_04735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHQ89_04740	COG0012	GTP binding
KHQ89_04745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHQ89_04750	COG1799	cell septum assembly
KHQ89_04760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KHQ89_04780	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHQ89_04785	COG0813	purine-nucleoside phosphorylase activity
KHQ89_04800	COG0612	Peptidase, M16
KHQ89_04805	COG0629	single-stranded DNA binding
KHQ89_04810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHQ89_04815	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHQ89_04820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHQ89_04830	COG0406	alpha-ribazole phosphatase activity
KHQ89_04835	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHQ89_04880	COG0582	viral genome integration into host DNA
KHQ89_04890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHQ89_04895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHQ89_04900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHQ89_04905	COG1490	D-aminoacyl-tRNA deacylase activity
KHQ89_04910	COG0519	Catalyzes the synthesis of GMP from XMP
KHQ89_04915	COG0124	histidyl-tRNA synthetase
KHQ89_04920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHQ89_04925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHQ89_04935	COG3480	Lon protease (S16) C-terminal proteolytic domain
KHQ89_04950	COG0564	pseudouridine synthase activity
KHQ89_04955	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHQ89_04960	COG1193	negative regulation of DNA recombination
KHQ89_04965	COG3118	belongs to the thioredoxin family
KHQ89_04970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHQ89_04975	COG0196	riboflavin kinase activity
KHQ89_04980	COG3870	Protein conserved in bacteria
KHQ89_04985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHQ89_05000	COG1185	polyribonucleotide nucleotidyltransferase activity
KHQ89_05010	COG2267	carboxylic ester hydrolase activity
KHQ89_05025	COG1253	flavin adenine dinucleotide binding
KHQ89_05030	COG4536	flavin adenine dinucleotide binding
KHQ89_05055	COG0481	GTPase activity
KHQ89_05060	COG3547	Transposase (IS116 IS110 IS902 family)
KHQ89_05065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHQ89_05070	COG4974	Belongs to the 'phage' integrase family
KHQ89_05075	COG4974	Belongs to the 'phage' integrase family
KHQ89_05100	COG0252	asparaginase activity
KHQ89_05115	COG0427	acetyl-CoA hydrolase
KHQ89_05140	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHQ89_05150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHQ89_05155	COG0596	Alpha beta hydrolase
KHQ89_05165	COG0183	Belongs to the thiolase family
KHQ89_05175	COG2086	electron transfer activity
KHQ89_05185	COG2030	dehydratase
KHQ89_05190	COG1309	transcriptional regulator
KHQ89_05200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHQ89_05210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHQ89_05215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHQ89_05220	COG0187	DNA topoisomerase II activity
KHQ89_05230	COG3763	UPF0154 protein
KHQ89_05240	COG0742	ribosomal rna small subunit methyltransferase
KHQ89_05245	COG1363	Peptidase, m42
KHQ89_05270	COG0052	Belongs to the universal ribosomal protein uS2 family
KHQ89_05280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KHQ89_05285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHQ89_05295	COG1121	(ABC) transporter
KHQ89_05310	COG0006	proline dipeptidase activity
KHQ89_05315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHQ89_05320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHQ89_05330	COG0656	L-ascorbic acid biosynthetic process
KHQ89_05335	COG1363	Peptidase, m42
KHQ89_05360	COG2255	four-way junction helicase activity
KHQ89_05365	COG0632	four-way junction helicase activity
KHQ89_05375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHQ89_05380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHQ89_05390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHQ89_05400	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHQ89_05405	COG4603	Belongs to the binding-protein-dependent transport system permease family
KHQ89_05410	COG3845	ABC transporter
KHQ89_05415	COG1744	ABC transporter substrate-binding protein PnrA-like
KHQ89_05435	COG0285	dihydrofolate synthase activity
KHQ89_05445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHQ89_05455	COG1307	EDD domain protein, DegV family
KHQ89_05460	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KHQ89_05465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHQ89_05470	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHQ89_05475	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHQ89_05500	COG0489	protein tyrosine kinase activity
KHQ89_05510	COG3706	GGDEF domain
KHQ89_05510	COG5001	Diguanylate cyclase
KHQ89_05510	COG4251	negative regulation of phosphorylation
KHQ89_05510	COG2203	Gaf domain
KHQ89_05515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHQ89_05560	COG0395	ABC-type sugar transport system, permease component
KHQ89_05565	COG1175	transmembrane transport
KHQ89_05610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHQ89_05620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHQ89_05625	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KHQ89_05630	COG2089	acid synthase
KHQ89_05645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHQ89_05670	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHQ89_05735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHQ89_05765	COG4974	Belongs to the 'phage' integrase family
KHQ89_05770	COG4974	Belongs to the 'phage' integrase family
KHQ89_05825	COG2801	Transposase and inactivated derivatives
KHQ89_05845	COG0004	ammonium transporteR
KHQ89_05850	COG1482	cell wall glycoprotein biosynthetic process
KHQ89_05860	COG3547	Transposase (IS116 IS110 IS902 family)
KHQ89_05880	COG5505	Protein of unknown function (DUF819)
KHQ89_05895	COG0170	dolichyl monophosphate biosynthetic process
KHQ89_05925	COG1609	Transcriptional regulator
KHQ89_05945	COG0395	ABC-type sugar transport system, permease component
KHQ89_05950	COG1175	transmembrane transport
KHQ89_05970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ89_05975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHQ89_05980	COG3835	regulator
KHQ89_05990	COG3842	ATPase activity
KHQ89_06010	COG0438	transferase activity, transferring glycosyl groups
KHQ89_06015	COG0366	Alpha amylase catalytic
KHQ89_06020	COG1929	Belongs to the glycerate kinase type-1 family
KHQ89_06025	COG5002	protein histidine kinase activity
KHQ89_06035	COG1136	(ABC) transporter
KHQ89_06040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHQ89_06045	COG1272	protein, Hemolysin III
KHQ89_06060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHQ89_06065	COG3022	response to hydroperoxide
KHQ89_06070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHQ89_06105	COG0018	arginyl-trna synthetase
KHQ89_06115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHQ89_06125	COG0297	glycogen (starch) synthase activity
KHQ89_06140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHQ89_06165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ89_06175	COG0497	DNA recombination
KHQ89_06185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHQ89_06190	COG1722	exodeoxyribonuclease VII activity
KHQ89_06195	COG1570	exodeoxyribonuclease VII activity
KHQ89_06200	COG1570	exodeoxyribonuclease VII activity
KHQ89_06205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHQ89_06210	COG2199	diguanylate cyclase activity
KHQ89_06210	COG2203	Gaf domain
KHQ89_06240	COG1177	transmembrane transport
KHQ89_06250	COG3839	Belongs to the ABC transporter superfamily
KHQ89_06340	COG5001	Diguanylate cyclase
KHQ89_06340	COG4251	negative regulation of phosphorylation
KHQ89_06340	COG3706	GGDEF domain
KHQ89_06340	COG2203	Gaf domain
KHQ89_06345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHQ89_06355	COG0534	Mate efflux family protein
KHQ89_06385	COG0492	ferredoxin-NADP+ reductase activity
KHQ89_06395	COG3279	Response regulator of the LytR AlgR family
KHQ89_06405	COG0569	domain protein
KHQ89_06425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHQ89_06440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHQ89_06445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KHQ89_06470	COG0194	GDP metabolic process
KHQ89_06475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHQ89_06480	COG0765	amino acid transport
KHQ89_06485	COG1126	abc transporter atp-binding protein
KHQ89_06490	COG0110	maltose O-acetyltransferase activity
KHQ89_06495	COG4895	conserved protein (DUF2196)
KHQ89_06510	COG1307	EDD domain protein, DegV family
KHQ89_06515	COG1461	Dihydroxyacetone kinase
KHQ89_06540	COG0488	(ABC) transporter
KHQ89_06565	COG2801	Transposase and inactivated derivatives
KHQ89_06570	COG0431	NADPH-dependent FMN reductase
KHQ89_06575	COG2514	catechol 2,3-dioxygenase activity
KHQ89_06580	COG1733	regulation of RNA biosynthetic process
KHQ89_06625	COG3177	Filamentation induced by cAMP protein fic
KHQ89_06690	COG3328	transposase activity
KHQ89_06705	COG0640	Transcriptional regulator
KHQ89_06740	COG0386	Belongs to the glutathione peroxidase family
KHQ89_06745	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KHQ89_06805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ89_06810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHQ89_06815	COG0653	protein targeting
KHQ89_06830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHQ89_06845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHQ89_06850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHQ89_06855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHQ89_06860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHQ89_06875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHQ89_06880	COG2251	uridine kinase activity
KHQ89_06880	COG0195	Participates in both transcription termination and antitermination
KHQ89_06885	COG0779	Required for maturation of 30S ribosomal subunits
KHQ89_06900	COG1121	(ABC) transporter
KHQ89_06905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHQ89_06915	COG0656	L-ascorbic acid biosynthetic process
KHQ89_06930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHQ89_06940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHQ89_06950	COG0322	excinuclease ABC activity
KHQ89_06955	COG1758	RNA polymerase activity
KHQ89_06960	COG0194	GDP metabolic process
KHQ89_06965	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KHQ89_06970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHQ89_06995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KHQ89_07000	COG1394	ATPase activity, coupled to movement of substances
KHQ89_07030	COG1269	ATP hydrolysis coupled proton transport
KHQ89_07050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHQ89_07065	COG2996	Protein conserved in bacteria
KHQ89_07075	COG1278	Cold shock
KHQ89_07080	COG1132	(ABC) transporter
KHQ89_07085	COG1132	(ABC) transporter
KHQ89_07130	COG0494	nUDIX hydrolase
KHQ89_07135	COG0798	PFAM Bile acid sodium symporter
KHQ89_07190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHQ89_07260	COG1461	Dihydroxyacetone kinase
KHQ89_07265	COG1461	Dihydroxyacetone kinase
KHQ89_07270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KHQ89_07275	COG0737	Belongs to the 5'-nucleotidase family
KHQ89_07285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHQ89_07290	COG1162	GTPase activity
KHQ89_07295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHQ89_07300	COG0072	phenylalanine-tRNA ligase activity
KHQ89_07300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ89_07305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ89_07305	COG0072	phenylalanine-tRNA ligase activity
KHQ89_07320	COG2176	DNA-directed DNA polymerase activity
KHQ89_07325	COG2176	DNA-directed DNA polymerase activity
KHQ89_07335	COG1242	4 iron, 4 sulfur cluster binding
KHQ89_07340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHQ89_07380	COG0366	Alpha amylase catalytic
KHQ89_07395	COG1609	Transcriptional regulator
KHQ89_07405	COG1523	belongs to the glycosyl hydrolase 13 family
KHQ89_07410	COG0366	Alpha amylase catalytic
KHQ89_07435	COG3833	ABC-type maltose transport systems, permease component
KHQ89_07440	COG1175	transmembrane transport
KHQ89_07465	COG1523	belongs to the glycosyl hydrolase 13 family
KHQ89_07510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHQ89_07525	COG1473	amidohydrolase
KHQ89_07530	COG2171	N-acyltransferase activity
KHQ89_07535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KHQ89_07540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHQ89_07545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHQ89_07550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHQ89_07560	COG0019	diaminopimelate decarboxylase activity
KHQ89_07565	COG0546	phosphoglycolate phosphatase activity
KHQ89_07605	COG1506	peptidase
KHQ89_07605	COG0823	Involved in the tonB-independent uptake of proteins
KHQ89_07605	COG4946	Tricorn protease homolog
KHQ89_07630	COG0765	amino acid transport
KHQ89_07635	COG1126	abc transporter atp-binding protein
KHQ89_07680	COG1396	sequence-specific DNA binding
KHQ89_07730	COG1131	(ABC) transporter
KHQ89_07755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHQ89_07780	COG2217	Heavy metal translocating P-type atpase
KHQ89_07785	COG0640	Transcriptional regulator
KHQ89_07795	COG0640	Transcriptional regulator
KHQ89_07820	COG2801	Transposase and inactivated derivatives
KHQ89_07870	COG2217	Heavy metal translocating P-type atpase
KHQ89_07905	COG0750	zinc metalloprotease
KHQ89_07920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHQ89_07925	COG0233	cytoplasmic translational termination
KHQ89_07930	COG0528	UMP kinase activity
KHQ89_07935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHQ89_07940	COG0052	Belongs to the universal ribosomal protein uS2 family
KHQ89_07950	COG0756	dUTP diphosphatase activity
KHQ89_07955	COG4974	Belongs to the 'phage' integrase family
KHQ89_07960	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHQ89_07970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHQ89_08005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHQ89_08020	COG1393	Belongs to the ArsC family
KHQ89_08025	COG1164	Oligoendopeptidase f
KHQ89_08035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHQ89_08050	COG1609	Transcriptional regulator
KHQ89_08060	COG0336	Belongs to the RNA methyltransferase TrmD family
KHQ89_08065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHQ89_08070	COG1837	Belongs to the UPF0109 family
KHQ89_08075	COG0228	four-way junction DNA binding
KHQ89_08090	COG1187	pseudouridine synthase activity
KHQ89_08095	COG0242	peptide deformylase activity
KHQ89_08105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ89_08110	COG0301	tRNA thio-modification
KHQ89_08115	COG1956	GAF domain-containing protein
KHQ89_08120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHQ89_08130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHQ89_08140	COG0126	phosphoglycerate kinase activity
KHQ89_08150	COG3842	ATPase activity
KHQ89_08155	COG2508	Transcriptional regulator
KHQ89_08175	COG0822	iron-sulfur transferase activity
KHQ89_08180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHQ89_08185	COG0719	Fe-S assembly protein
KHQ89_08190	COG0396	ATPase activity
KHQ89_08220	COG0444	Belongs to the ABC transporter superfamily
KHQ89_08225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ89_08230	COG0601	transmembrane transport
KHQ89_08245	COG4166	transmembrane transport
KHQ89_08255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHQ89_08270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHQ89_08340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHQ89_08345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides