locus-tag	class	description
FHG85_00025	COG0756	dUTP diphosphatase activity
FHG85_00040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FHG85_00050	COG2255	four-way junction helicase activity
FHG85_00055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FHG85_00065	COG0006	proline dipeptidase activity
FHG85_00080	COG1131	(ABC) transporter
FHG85_00100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FHG85_00105	COG0318	PFAM AMP-dependent synthetase and ligase
FHG85_00155	COG0616	signal peptide processing
FHG85_00160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FHG85_00165	COG3040	lipid binding
FHG85_00170	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FHG85_00175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FHG85_00180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FHG85_00185	COG1993	acr, cog1993
FHG85_00190	COG0544	peptidyl-prolyl cis-trans isomerase activity
FHG85_00195	COG0740	serine-type endopeptidase activity
FHG85_00210	COG1940	carbohydrate kinase activity
FHG85_00215	COG1760	l-serine dehydratase
FHG85_00220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHG85_00235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHG85_00245	COG0297	glycogen (starch) synthase activity
FHG85_00255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FHG85_00265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FHG85_00270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FHG85_00280	COG1121	(ABC) transporter
FHG85_00285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHG85_00300	COG1595	DNA-templated transcription, initiation
FHG85_00320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHG85_00330	COG0358	DNA primase activity
FHG85_00340	COG1716	ATPase activity
FHG85_00340	COG1131	(ABC) transporter
FHG85_00340	COG0842	Transport permease protein
FHG85_00350	COG2204	response regulator
FHG85_00365	COG0009	L-threonylcarbamoyladenylate synthase
FHG85_00370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHG85_00375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FHG85_00385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FHG85_00405	COG2252	PERMEase
FHG85_00460	COG0367	asparagine synthase
FHG85_00470	COG0297	glycogen (starch) synthase activity
FHG85_00480	COG0688	phosphatidylethanolamine metabolic process
FHG85_00495	COG0124	histidyl-tRNA synthetase
FHG85_00500	COG2986	histidine ammonia-lyase
FHG85_00510	COG2003	Belongs to the UPF0758 family
FHG85_00515	COG1086	Polysaccharide biosynthesis protein
FHG85_00520	COG3787	Belongs to the UPF0306 family
FHG85_00525	COG3757	hydrolase, family 25
FHG85_00530	COG3852	Histidine kinase
FHG85_00535	COG0569	domain protein
FHG85_00540	COG2333	competence protein COMEC
FHG85_00540	COG0658	competence protein
FHG85_00550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHG85_00595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_00625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FHG85_00640	COG0268	Binds directly to 16S ribosomal RNA
FHG85_00650	COG0784	Response regulator, receiver
FHG85_00650	COG2205	protein histidine kinase activity
FHG85_00655	COG3876	Protein conserved in bacteria
FHG85_00660	COG0328	RNA-DNA hybrid ribonuclease activity
FHG85_00660	COG3341	Caulimovirus viroplasmin
FHG85_00670	COG1663	tetraacyldisaccharide 4'-kinase activity
FHG85_00675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FHG85_00680	COG1040	competence protein
FHG85_00700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FHG85_00700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FHG85_00705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FHG85_00715	COG4172	Belongs to the ABC transporter superfamily
FHG85_00720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FHG85_00740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FHG85_00760	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FHG85_00760	COG0662	Cupin 2, conserved barrel domain protein
FHG85_00765	COG0306	phosphate transporter
FHG85_00770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FHG85_00785	COG1027	Aspartate ammonia-lyase
FHG85_00820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHG85_00835	COG1774	PSP1 C-terminal conserved region
FHG85_00840	COG0470	DNA polymerase III
FHG85_00845	COG0126	phosphoglycerate kinase activity
FHG85_00850	COG1342	Belongs to the UPF0251 family
FHG85_00865	COG0730	response to heat
FHG85_00870	COG1473	amidohydrolase
FHG85_00880	COG2920	part of a sulfur-relay system
FHG85_00885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FHG85_00895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHG85_00900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FHG85_00905	COG0557	exoribonuclease II activity
FHG85_00935	COG2274	protein secretion by the type I secretion system
FHG85_00970	COG0180	Tryptophanyl-tRNA synthetase
FHG85_00990	COG0017	Asparaginyl-tRNA synthetase
FHG85_00995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FHG85_01005	COG0163	prenyltransferase activity
FHG85_01020	COG0321	lipoyl(octanoyl) transferase activity
FHG85_01025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FHG85_01025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FHG85_01030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHG85_01035	COG0484	heat shock protein binding
FHG85_01040	COG0489	protein tyrosine kinase activity
FHG85_01045	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FHG85_01050	COG0719	Fe-S assembly protein
FHG85_01060	COG0396	ATPase activity
FHG85_01065	COG0719	Fe-S assembly protein
FHG85_01075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHG85_01095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_01105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FHG85_01115	COG0606	chelatase, subunit chli
FHG85_01120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHG85_01130	COG0495	leucyl-tRNA aminoacylation
FHG85_01140	COG0628	permease
FHG85_01155	COG1668	transmembrane transport
FHG85_01160	COG4152	abc transporter atp-binding protein
FHG85_01180	COG0802	atpase or kinase
FHG85_01185	COG0686	Belongs to the AlaDH PNT family
FHG85_01195	COG4942	peptidase
FHG85_01200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FHG85_01210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FHG85_01230	COG2315	Protein conserved in bacteria
FHG85_01235	COG0792	nuclease activity
FHG85_01245	COG1619	proteins homologs of microcin C7 resistance protein MccF
FHG85_01255	COG5002	protein histidine kinase activity
FHG85_01265	COG1473	amidohydrolase
FHG85_01270	COG0697	spore germination
FHG85_01280	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_01285	COG0047	phosphoribosylformylglycinamidine synthase activity
FHG85_01295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHG85_01305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHG85_01335	COG1716	ATPase activity
FHG85_01335	COG1131	(ABC) transporter
FHG85_01335	COG0842	Transport permease protein
FHG85_01350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FHG85_01360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHG85_01365	COG2094	Belongs to the DNA glycosylase MPG family
FHG85_01380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FHG85_01400	COG0726	polysaccharide deacetylase
FHG85_01435	COG0233	cytoplasmic translational termination
FHG85_01440	COG0528	UMP kinase activity
FHG85_01455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FHG85_01460	COG1349	DNA-binding transcription factor activity
FHG85_01465	COG0688	phosphatidylethanolamine metabolic process
FHG85_01470	COG4589	Belongs to the CDS family
FHG85_01480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FHG85_01520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FHG85_01525	COG1053	succinate dehydrogenase
FHG85_01535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHG85_01540	COG1160	GTP binding
FHG85_01555	COG0572	uridine kinase
FHG85_01560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FHG85_01575	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FHG85_01580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FHG85_01595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FHG85_01610	COG0596	Alpha beta hydrolase
FHG85_01620	COG0572	uridine kinase
FHG85_01625	COG1482	cell wall glycoprotein biosynthetic process
FHG85_01660	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FHG85_01670	COG0784	Response regulator, receiver
FHG85_01670	COG2205	protein histidine kinase activity
FHG85_01675	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FHG85_01685	COG0460	homoserine dehydrogenase
FHG85_01690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FHG85_01705	COG0154	amidase activity
FHG85_01710	COG0612	Peptidase, M16
FHG85_01715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHG85_01760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHG85_01765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FHG85_01775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHG85_01785	COG1137	ATPase activity
FHG85_01800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FHG85_01805	COG0228	four-way junction DNA binding
FHG85_01820	COG3279	Response regulator of the LytR AlgR family
FHG85_01825	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FHG85_01830	COG0242	peptide deformylase activity
FHG85_01840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FHG85_01845	COG0052	Belongs to the universal ribosomal protein uS2 family
FHG85_01850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FHG85_01900	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FHG85_01905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FHG85_01910	COG0632	four-way junction helicase activity
FHG85_01920	COG0509	glycine decarboxylation via glycine cleavage system
FHG85_01925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FHG85_01930	COG0739	heme binding
FHG85_01935	COG0084	hydrolase, TatD family'
FHG85_01940	COG0252	asparaginase activity
FHG85_01950	COG0811	peptide transport
FHG85_01970	COG1785	Belongs to the alkaline phosphatase family
FHG85_02010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FHG85_02010	COG0116	Belongs to the methyltransferase superfamily
FHG85_02015	COG0826	peptidase U32
FHG85_02020	COG0561	phosphatase activity
FHG85_02030	COG0590	tRNA wobble adenosine to inosine editing
FHG85_02035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FHG85_02045	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_02045	COG4946	Tricorn protease homolog
FHG85_02045	COG1506	peptidase
FHG85_02050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHG85_02055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FHG85_02075	COG4535	Mg2 and Co2 transporter CorC
FHG85_02080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHG85_02095	COG2885	chlorophyll binding
FHG85_02100	COG2095	MarC family integral membrane protein
FHG85_02120	COG3958	Transketolase
FHG85_02125	COG3959	Transketolase, thiamine diphosphate binding domain
FHG85_02140	COG0217	transcriptional regulatory protein
FHG85_02145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHG85_02160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FHG85_02165	COG0527	aspartate kinase activity
FHG85_02170	COG0745	RESPONSE REGULATOR receiver
FHG85_02175	COG5002	protein histidine kinase activity
FHG85_02185	COG2885	chlorophyll binding
FHG85_02215	COG0463	Glycosyl transferase, family 2
FHG85_02245	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FHG85_02255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHG85_02260	COG1045	serine acetyltransferase
FHG85_02265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHG85_02270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FHG85_02275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FHG85_02285	COG4585	Histidine kinase
FHG85_02290	COG2197	response regulator
FHG85_02325	COG2205	protein histidine kinase activity
FHG85_02325	COG0784	Response regulator, receiver
FHG85_02335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FHG85_02365	COG1309	transcriptional regulator
FHG85_02405	COG1595	DNA-templated transcription, initiation
FHG85_02420	COG0612	Peptidase, M16
FHG85_02425	COG0604	alcohol dehydrogenase
FHG85_02435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHG85_02460	COG1519	Transferase
FHG85_02465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_02470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FHG85_02470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FHG85_02475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_02480	COG1078	dGTPase activity
FHG85_02570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_02580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHG85_02610	COG0254	rRNA binding
FHG85_02620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FHG85_02625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FHG85_02635	COG1051	belongs to the nudix hydrolase family
FHG85_02640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FHG85_02665	COG1136	(ABC) transporter
FHG85_02665	COG0577	efflux transmembrane transporter activity
FHG85_02690	COG2001	Belongs to the MraZ family
FHG85_02695	COG0275	rRNA processing
FHG85_02705	COG0768	penicillin binding
FHG85_02715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHG85_02720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FHG85_02725	COG0772	Belongs to the SEDS family
FHG85_02730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FHG85_02735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FHG85_02765	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FHG85_02790	COG1295	ribonuclease BN
FHG85_02795	COG0778	Nitroreductase
FHG85_02795	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FHG85_02800	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FHG85_02835	COG1902	pentaerythritol trinitrate reductase activity
FHG85_02835	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHG85_02840	COG0166	Belongs to the GPI family
FHG85_02845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHG85_02850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHG85_02875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHG85_02885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FHG85_02885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FHG85_02895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FHG85_02900	COG0598	Magnesium transport protein CorA
FHG85_02930	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHG85_02930	COG1388	LysM domain
FHG85_02935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FHG85_02950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHG85_02960	COG1335	isochorismatase
FHG85_02990	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FHG85_03010	COG0488	(ABC) transporter
FHG85_03030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FHG85_03035	COG0196	riboflavin kinase activity
FHG85_03050	COG0438	transferase activity, transferring glycosyl groups
FHG85_03065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FHG85_03075	COG0138	bifunctional purine biosynthesis protein purh
FHG85_03095	COG0768	penicillin binding
FHG85_03100	COG0772	Belongs to the SEDS family
FHG85_03110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_03120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FHG85_03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHG85_03135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FHG85_03145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_03235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHG85_03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_03255	COG1136	(ABC) transporter
FHG85_03260	COG1136	(ABC) transporter
FHG85_03260	COG0577	efflux transmembrane transporter activity
FHG85_03270	COG3279	Response regulator of the LytR AlgR family
FHG85_03295	COG0492	ferredoxin-NADP+ reductase activity
FHG85_03300	COG1233	COG1233 Phytoene dehydrogenase and related
FHG85_03310	COG3104	oligopeptide transport
FHG85_03315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FHG85_03315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FHG85_03350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FHG85_03365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FHG85_03375	COG0305	Participates in initiation and elongation during chromosome replication
FHG85_03390	COG0724	RNA recognition motif
FHG85_03395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FHG85_03405	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHG85_03405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHG85_03410	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_03435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FHG85_03450	COG0494	nUDIX hydrolase
FHG85_03455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHG85_03460	COG1678	Uncharacterized ACR, COG1678
FHG85_03465	COG1757	Na H antiporter
FHG85_03470	COG0022	dehydrogenase e1 component
FHG85_03485	COG1477	protein flavinylation
FHG85_03505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FHG85_03510	COG0129	dihydroxy-acid dehydratase activity
FHG85_03515	COG0028	Belongs to the TPP enzyme family
FHG85_03520	COG0440	acetolactate synthase activity
FHG85_03525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FHG85_03530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FHG85_03535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FHG85_03540	COG0066	3-isopropylmalate dehydratase activity
FHG85_03550	COG0473	3-isopropylmalate dehydrogenase activity
FHG85_03560	COG0302	gtp cyclohydrolase
FHG85_03575	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FHG85_03590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHG85_03605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHG85_03615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FHG85_03620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FHG85_03625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FHG85_03630	COG0204	Acyl-transferase
FHG85_03660	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHG85_03665	COG3239	Fatty acid desaturase
FHG85_03700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FHG85_03720	COG0848	biopolymer transport protein
FHG85_03725	COG0811	peptide transport
FHG85_03735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FHG85_03740	COG2205	protein histidine kinase activity
FHG85_03740	COG2198	Histidine kinase
FHG85_03740	COG0784	Response regulator, receiver
FHG85_03740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHG85_03745	COG3022	response to hydroperoxide
FHG85_03755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHG85_03765	COG0038	chloride channel
FHG85_03770	COG0612	Peptidase, M16
FHG85_03785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHG85_03790	COG0735	belongs to the Fur family
FHG85_03795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FHG85_03820	COG0318	PFAM AMP-dependent synthetase and ligase
FHG85_03830	COG1136	(ABC) transporter
FHG85_03835	COG2096	Adenosyltransferase
FHG85_03850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHG85_03860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHG85_03865	COG0516	GMP reductase activity
FHG85_03865	COG0517	IMP dehydrogenase activity
FHG85_03880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_03905	COG0668	transmembrane transport
FHG85_03910	COG0590	tRNA wobble adenosine to inosine editing
FHG85_03920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHG85_03925	COG0488	(ABC) transporter
FHG85_03945	COG2878	Part of a membrane complex involved in electron transport
FHG85_03945	COG1245	4Fe-4S binding domain
FHG85_03950	COG4656	Part of a membrane complex involved in electron transport
FHG85_03955	COG4658	electron transport chain
FHG85_03960	COG4659	FMN binding
FHG85_03965	COG4660	Part of a membrane complex involved in electron transport
FHG85_03970	COG4657	Part of a membrane complex involved in electron transport
FHG85_03975	COG3291	Pkd domain containing protein
FHG85_03980	COG2186	Transcriptional regulator
FHG85_03985	COG4771	TonB-dependent receptor
FHG85_03990	COG0702	epimerase
FHG85_04020	COG2271	Major facilitator Superfamily
FHG85_04025	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_04035	COG0800	Aldolase
FHG85_04040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHG85_04045	COG0739	heme binding
FHG85_04060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FHG85_04085	COG1704	LemA family
FHG85_04100	COG1518	maintenance of DNA repeat elements
FHG85_04105	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FHG85_04115	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FHG85_04135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FHG85_04155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FHG85_04160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHG85_04170	COG0390	transport system, permease component
FHG85_04175	COG0488	(ABC) transporter
FHG85_04180	COG3457	Alanine racemase
FHG85_04220	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FHG85_04230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FHG85_04240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHG85_04260	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FHG85_04265	COG1805	sodium ion transport
FHG85_04270	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FHG85_04280	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FHG85_04285	COG2871	sodium ion transport
FHG85_04305	COG4221	oxidoreductase activity
FHG85_04310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHG85_04315	COG2226	methyltransferase
FHG85_04325	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FHG85_04330	COG1876	peptidase activity
FHG85_04340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHG85_04350	COG1830	Aldolase
FHG85_04355	COG0733	neurotransmitter:sodium symporter activity
FHG85_04360	COG1115	amino acid carrier protein
FHG85_04370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FHG85_04375	COG4974	Belongs to the 'phage' integrase family
FHG85_04405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FHG85_04425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FHG85_04430	COG0081	regulation of translation
FHG85_04435	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FHG85_04440	COG0222	ribosome binding
FHG85_04445	COG0085	RNA polymerase activity
FHG85_04475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FHG85_04475	COG0493	'glutamate synthase
FHG85_04510	COG1082	Xylose isomerase domain protein TIM barrel
FHG85_04515	COG1966	Carbon starvation protein
FHG85_04525	COG0602	queuosine metabolic process
FHG85_04530	COG2985	domain, Protein
FHG85_04535	COG0339	signal peptide processing
FHG85_04540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHG85_04570	COG0492	ferredoxin-NADP+ reductase activity
FHG85_04575	COG0156	8-amino-7-oxononanoate synthase activity
FHG85_04600	COG0497	DNA recombination
FHG85_04605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FHG85_04610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHG85_04625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FHG85_04650	COG0187	DNA topoisomerase II activity
FHG85_04665	COG1741	Belongs to the pirin family
FHG85_04670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FHG85_04675	COG2217	Heavy metal translocating P-type atpase
FHG85_04680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHG85_04690	COG2205	protein histidine kinase activity
FHG85_04700	COG1971	Probably functions as a manganese efflux pump
FHG85_04705	COG2885	chlorophyll binding
FHG85_04725	COG0746	molybdenum cofactor guanylyltransferase activity
FHG85_04730	COG0009	L-threonylcarbamoyladenylate synthase
FHG85_04735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FHG85_04740	COG3279	Response regulator of the LytR AlgR family
FHG85_04745	COG0745	RESPONSE REGULATOR receiver
FHG85_04750	COG0556	nucleotide-excision repair
FHG85_04755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHG85_04775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHG85_04785	COG1288	antiporter activity
FHG85_04805	COG0025	NhaP-type Na H and K H
FHG85_04815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FHG85_04825	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_04830	COG0205	6-phosphofructokinase activity
FHG85_04845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FHG85_04860	COG0542	response to heat
FHG85_04865	COG1074	ATP-dependent DNA helicase activity
FHG85_04870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_04875	COG1242	4 iron, 4 sulfur cluster binding
FHG85_04890	COG0840	transmembrane signaling receptor activity
FHG85_04895	COG3033	Beta-eliminating lyase
FHG85_04910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FHG85_04920	COG2204	response regulator
FHG85_04930	COG0527	aspartate kinase activity
FHG85_04935	COG0019	diaminopimelate decarboxylase activity
FHG85_04940	COG0318	PFAM AMP-dependent synthetase and ligase
FHG85_04945	COG1216	Glycosyl transferase, family 2
FHG85_04955	COG0483	inositol monophosphate 1-phosphatase activity
FHG85_04965	COG0602	queuosine metabolic process
FHG85_04970	COG0737	Belongs to the 5'-nucleotidase family
FHG85_04975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHG85_05010	COG0840	transmembrane signaling receptor activity
FHG85_05015	COG0534	Mate efflux family protein
FHG85_05025	COG1368	sulfuric ester hydrolase activity
FHG85_05045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FHG85_05055	COG1320	monovalent cation:proton antiporter activity
FHG85_05065	COG1863	multisubunit Na H antiporter MnhE subunit
FHG85_05070	COG0651	ATP synthesis coupled electron transport
FHG85_05075	COG1006	Multisubunit Na H antiporter MnhC subunit
FHG85_05080	COG2111	Na H antiporter
FHG85_05085	COG2111	Na H antiporter
FHG85_05085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FHG85_05090	COG4251	negative regulation of phosphorylation
FHG85_05100	COG1765	OsmC-like protein
FHG85_05115	COG3118	belongs to the thioredoxin family
FHG85_05130	COG1446	asparaginase
FHG85_05175	COG1120	ATPase activity
FHG85_05180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FHG85_05235	COG1151	hydroxylamine reductase activity
FHG85_05250	COG3005	denitrification pathway
FHG85_05255	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FHG85_05265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FHG85_05280	COG0336	Belongs to the RNA methyltransferase TrmD family
FHG85_05290	COG1331	Highly conserved protein containing a thioredoxin domain
FHG85_05300	COG0071	Belongs to the small heat shock protein (HSP20) family
FHG85_05310	COG0504	CTP synthase activity
FHG85_05315	COG0706	membrane insertase activity
FHG85_05320	COG1228	amidohydrolase
FHG85_05345	COG0442	prolyl-tRNA aminoacylation
FHG85_05370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHG85_05375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHG85_05380	COG0037	tRNA processing
FHG85_05385	COG0488	(ABC) transporter
FHG85_05410	COG1714	RDD family
FHG85_05415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FHG85_05420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FHG85_05425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FHG85_05440	COG3591	Belongs to the peptidase S1B family
FHG85_05455	COG3279	Response regulator of the LytR AlgR family
FHG85_05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHG85_05465	COG2205	protein histidine kinase activity
FHG85_05465	COG0784	Response regulator, receiver
FHG85_05465	COG2198	Histidine kinase
FHG85_05500	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHG85_05505	COG1218	3'(2'),5'-bisphosphate nucleotidase
FHG85_05515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FHG85_05525	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHG85_05535	COG0251	oxidation-reduction process
FHG85_05540	COG0359	binds to the 23S rRNA
FHG85_05545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FHG85_05550	COG0360	Binds together with S18 to 16S ribosomal RNA
FHG85_05560	COG0813	purine-nucleoside phosphorylase activity
FHG85_05575	COG0612	Peptidase, M16
FHG85_05580	COG2843	Capsule synthesis protein
FHG85_05585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FHG85_05595	COG1254	Belongs to the acylphosphatase family
FHG85_05605	COG0724	RNA recognition motif
FHG85_05610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHG85_05615	COG0549	Belongs to the carbamate kinase family
FHG85_05625	COG1674	ftsk spoiiie
FHG85_05635	COG0529	Catalyzes the synthesis of activated sulfate
FHG85_05640	COG0175	sulfate reduction
FHG85_05655	COG0791	NLP P60 protein
FHG85_05700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FHG85_05710	COG4974	Belongs to the 'phage' integrase family
FHG85_05720	COG0793	Belongs to the peptidase S41A family
FHG85_05720	COG4946	Tricorn protease homolog
FHG85_05730	COG0339	signal peptide processing
FHG85_05735	COG1509	lysine 2,3-aminomutase activity
FHG85_05745	COG0321	lipoyl(octanoyl) transferase activity
FHG85_05745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FHG85_05755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHG85_05770	COG0544	peptidyl-prolyl cis-trans isomerase activity
FHG85_05775	COG0545	Peptidyl-prolyl cis-trans isomerase
FHG85_05780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHG85_05785	COG0105	UTP biosynthetic process
FHG85_05795	COG0742	ribosomal rna small subunit methyltransferase
FHG85_05840	COG0511	ligase activity, forming carbon-carbon bonds
FHG85_05840	COG5016	pyruvate
FHG85_05855	COG0574	Belongs to the PEP-utilizing enzyme family
FHG85_05855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FHG85_05860	COG1506	peptidase
FHG85_05860	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_05875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FHG85_05880	COG1472	Belongs to the glycosyl hydrolase 3 family
FHG85_05885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FHG85_05905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHG85_05920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHG85_05925	COG0840	transmembrane signaling receptor activity
FHG85_05935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FHG85_05945	COG1979	alcohol dehydrogenase
FHG85_05965	COG0437	4 iron, 4 sulfur cluster binding
FHG85_05975	COG0626	cystathionine gamma-synthase activity
FHG85_05985	COG0735	belongs to the Fur family
FHG85_05995	COG0450	alkyl hydroperoxide reductase
FHG85_06005	COG0010	Belongs to the arginase family
FHG85_06030	COG0339	signal peptide processing
FHG85_06050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_06055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHG85_06085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FHG85_06090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FHG85_06100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHG85_06110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FHG85_06120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FHG85_06125	COG0167	dihydroorotate dehydrogenase activity
FHG85_06135	COG1809	phosphosulfolactate synthase activity
FHG85_06155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FHG85_06170	COG1629	transport
FHG85_06170	COG4206	TonB-dependent receptor
FHG85_06175	COG1609	Transcriptional regulator
FHG85_06190	COG3279	Response regulator of the LytR AlgR family
FHG85_06195	COG2972	Histidine kinase
FHG85_06240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHG85_06250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHG85_06275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FHG85_06305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHG85_06310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHG85_06330	COG0402	S-adenosylhomocysteine deaminase activity
FHG85_06335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FHG85_06340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHG85_06360	COG0493	'glutamate synthase
FHG85_06360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FHG85_06455	COG1131	(ABC) transporter
FHG85_06460	COG1131	(ABC) transporter
FHG85_06465	COG0842	Transport permease protein
FHG85_06470	COG0842	Transport permease protein
FHG85_06485	COG0243	molybdopterin cofactor binding
FHG85_06490	COG0437	4 iron, 4 sulfur cluster binding
FHG85_06515	COG0277	FAD linked oxidase domain protein
FHG85_06515	COG0247	lactate metabolic process
FHG85_06520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHG85_06525	COG0280	phosphate acetyltransferase
FHG85_06535	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_06545	COG1278	Cold shock
FHG85_06560	COG1301	dicarboxylic acid transport
FHG85_06570	COG1716	ATPase activity
FHG85_06570	COG1131	(ABC) transporter
FHG85_06570	COG0842	Transport permease protein
FHG85_06595	COG0784	Response regulator, receiver
FHG85_06605	COG2202	Pas domain
FHG85_06605	COG2205	protein histidine kinase activity
FHG85_06610	COG0784	Response regulator, receiver
FHG85_06610	COG0835	chemotaxis
FHG85_06620	COG2201	protein-glutamate methylesterase activity
FHG85_06625	COG2201	protein-glutamate methylesterase activity
FHG85_06630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHG85_06640	COG0840	transmembrane signaling receptor activity
FHG85_06645	COG0835	chemotaxis
FHG85_06650	COG2198	Histidine kinase
FHG85_06650	COG0643	Histidine kinase
FHG85_06655	COG2201	protein-glutamate methylesterase activity
FHG85_06665	COG2197	response regulator
FHG85_06675	COG4251	negative regulation of phosphorylation
FHG85_06680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FHG85_06690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHG85_06695	COG1554	hydrolase, family 65, central catalytic
FHG85_06700	COG0191	fructose-bisphosphate aldolase activity
FHG85_06705	COG0366	Alpha amylase catalytic
FHG85_06720	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_06725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHG85_06740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FHG85_06745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FHG85_06760	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_06775	COG1546	Belongs to the CinA family
FHG85_06775	COG1058	Belongs to the CinA family
FHG85_06780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FHG85_06785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FHG85_06795	COG0552	protein localization to endoplasmic reticulum
FHG85_06800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHG85_06805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FHG85_06810	COG0542	response to heat
FHG85_06815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHG85_06840	COG0709	Synthesizes selenophosphate from selenide and ATP
FHG85_06855	COG0425	Belongs to the sulfur carrier protein TusA family
FHG85_06860	COG0167	dihydroorotate dehydrogenase activity
FHG85_06880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHG85_06885	COG1032	radical SAM domain protein
FHG85_06890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHG85_06910	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FHG85_06925	COG0626	cystathionine gamma-synthase activity
FHG85_06930	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FHG85_06935	COG2234	aminopeptidase activity
FHG85_06940	COG0386	Belongs to the glutathione peroxidase family
FHG85_06985	COG0714	Associated with various cellular activities
FHG85_06990	COG0101	tRNA pseudouridine synthase activity
FHG85_07065	COG0501	Belongs to the peptidase M48B family
FHG85_07075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FHG85_07080	COG0281	malic enzyme
FHG85_07085	COG2135	peptidase activity
FHG85_07090	COG1489	DNA binding
FHG85_07110	COG0133	tryptophan synthase activity
FHG85_07140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FHG85_07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FHG85_07150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FHG85_07155	COG0131	Imidazoleglycerol-phosphate dehydratase
FHG85_07160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FHG85_07165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FHG85_07170	COG0107	imidazoleglycerol-phosphate synthase activity
FHG85_07175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FHG85_07175	COG0140	phosphoribosyl-ATP diphosphatase activity
FHG85_07185	COG1278	Cold shock
FHG85_07190	COG1408	metallophosphoesterase
FHG85_07235	COG4251	negative regulation of phosphorylation
FHG85_07240	COG0784	Response regulator, receiver
FHG85_07245	COG0784	Response regulator, receiver
FHG85_07245	COG2205	protein histidine kinase activity
FHG85_07245	COG2198	Histidine kinase
FHG85_07250	COG1115	amino acid carrier protein
FHG85_07260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FHG85_07270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FHG85_07275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHG85_07285	COG0653	protein targeting
FHG85_07290	COG0018	arginyl-trna synthetase
FHG85_07300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHG85_07305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FHG85_07325	COG2201	protein-glutamate methylesterase activity
FHG85_07330	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FHG85_07335	COG2205	protein histidine kinase activity
FHG85_07335	COG0784	Response regulator, receiver
FHG85_07345	COG0835	chemotaxis
FHG85_07350	COG2198	Histidine kinase
FHG85_07350	COG0643	Histidine kinase
FHG85_07355	COG0745	RESPONSE REGULATOR receiver
FHG85_07375	COG0784	Response regulator, receiver
FHG85_07385	COG2204	response regulator
FHG85_07410	COG0217	transcriptional regulatory protein
FHG85_07435	COG1335	isochorismatase
FHG85_07450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHG85_07455	COG4771	TonB-dependent receptor
FHG85_07465	COG0484	heat shock protein binding
FHG85_07470	COG0237	dephospho-CoA kinase activity
FHG85_07480	COG1862	Preprotein translocase
FHG85_07490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHG85_07500	COG1918	ferrous iron import across plasma membrane
FHG85_07500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FHG85_07515	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FHG85_07520	COG0352	thiamine-phosphate diphosphorylase activity
FHG85_07525	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FHG85_07560	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FHG85_07565	COG0194	GDP metabolic process
FHG85_07570	COG1561	YicC-like family, N-terminal region
FHG85_07590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FHG85_07600	COG0335	large ribosomal subunit rRNA binding
FHG85_07610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FHG85_07615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FHG85_07625	COG0778	Nitroreductase
FHG85_07635	COG0405	Gamma-glutamyltransferase
FHG85_07660	COG0567	Dehydrogenase, E1 component
FHG85_07710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FHG85_07715	COG3279	Response regulator of the LytR AlgR family
FHG85_07745	COG1132	(ABC) transporter
FHG85_07750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHG85_07760	COG1030	water channel activity
FHG85_07765	COG1247	-acetyltransferase
FHG85_07775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FHG85_07780	COG0436	Aminotransferase
FHG85_07790	COG0561	phosphatase activity
FHG85_07805	COG0179	Fumarylacetoacetate (FAA) hydrolase
FHG85_07825	COG0592	DNA-directed DNA polymerase activity
FHG85_07845	COG2385	sporulation resulting in formation of a cellular spore
FHG85_07850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_07860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FHG85_07875	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_07875	COG1506	peptidase
FHG85_07890	COG1716	ATPase activity
FHG85_07890	COG1131	(ABC) transporter
FHG85_07890	COG0842	Transport permease protein
FHG85_07905	COG0116	Belongs to the methyltransferase superfamily
FHG85_07910	COG0513	Belongs to the DEAD box helicase family
FHG85_07915	COG0793	Belongs to the peptidase S41A family
FHG85_07915	COG3409	Peptidoglycan-binding domain 1 protein
FHG85_07920	COG0519	Catalyzes the synthesis of GMP from XMP
FHG85_07920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FHG85_07925	COG1234	tRNA 3'-trailer cleavage
FHG85_07935	COG0539	negative regulation of cytoplasmic translation
FHG85_07945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FHG85_07955	COG1091	dTDP-4-dehydrorhamnose reductase activity
FHG85_07960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHG85_07970	COG0006	proline dipeptidase activity
FHG85_07975	COG5002	protein histidine kinase activity
FHG85_07975	COG0784	Response regulator, receiver
FHG85_07995	COG0432	Pfam Uncharacterised protein family UPF0047
FHG85_08005	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FHG85_08005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHG85_08005	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHG85_08005	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_08020	COG2234	aminopeptidase activity
FHG85_08040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FHG85_08060	COG0438	transferase activity, transferring glycosyl groups
FHG85_08060	COG0297	glycogen (starch) synthase activity
FHG85_08080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHG85_08090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHG85_08105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FHG85_08110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHG85_08150	COG3250	beta-galactosidase activity
FHG85_08160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FHG85_08165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FHG85_08180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FHG85_08185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FHG85_08205	COG1418	mRNA catabolic process
FHG85_08220	COG0739	heme binding
FHG85_08245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FHG85_08270	COG0716	FMN binding
FHG85_08275	COG0501	Belongs to the peptidase M48B family
FHG85_08280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHG85_08290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHG85_08305	COG0196	riboflavin kinase activity
FHG85_08310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FHG85_08315	COG2205	protein histidine kinase activity
FHG85_08320	COG0745	RESPONSE REGULATOR receiver
FHG85_08325	COG4191	Histidine kinase
FHG85_08380	COG0482	sulfurtransferase activity
FHG85_08430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FHG85_08440	COG1811	Na channel or pump
FHG85_08450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHG85_08490	COG3383	formate dehydrogenase (NAD+) activity
FHG85_08505	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FHG85_08510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FHG85_08515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FHG85_08520	COG2226	methyltransferase
FHG85_08535	COG3279	Response regulator of the LytR AlgR family
FHG85_08540	COG3275	phosphorelay sensor kinase activity
FHG85_08575	COG0842	Transport permease protein
FHG85_08575	COG1716	ATPase activity
FHG85_08575	COG1131	(ABC) transporter
FHG85_08585	COG0745	RESPONSE REGULATOR receiver
FHG85_08590	COG4206	TonB-dependent receptor
FHG85_08590	COG1629	transport
FHG85_08595	COG4412	M6 family metalloprotease domain protein
FHG85_08595	COG1404	Belongs to the peptidase S8 family
FHG85_08615	COG0167	dihydroorotate dehydrogenase activity
FHG85_08625	COG3118	belongs to the thioredoxin family
FHG85_08630	COG1611	Belongs to the LOG family
FHG85_08660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FHG85_08670	COG1131	(ABC) transporter
FHG85_08675	COG0514	ATP-dependent DNA helicase (RecQ)
FHG85_08680	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FHG85_08680	COG0517	IMP dehydrogenase activity
FHG85_08685	COG0805	protein transport
FHG85_08695	COG1715	Restriction endonuclease
FHG85_08715	COG3328	transposase activity
FHG85_08720	COG4221	oxidoreductase activity
FHG85_08735	COG2137	regulation of response to DNA damage stimulus
FHG85_08740	COG2890	protein-(glutamine-N5) methyltransferase activity
FHG85_08745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHG85_08745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHG85_08750	COG0793	Belongs to the peptidase S41A family
FHG85_08760	COG0671	phosphoesterase, PA-phosphatase related
FHG85_08765	COG1803	Methylglyoxal synthase
FHG85_08780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHG85_08815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHG85_08820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHG85_08840	COG1739	Uncharacterized protein family UPF0029
FHG85_08845	COG0540	Belongs to the ATCase OTCase family
FHG85_08850	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FHG85_08870	COG1166	arginine decarboxylase activity
FHG85_08880	COG1496	oxidoreductase activity
FHG85_08885	COG3279	Response regulator of the LytR AlgR family
FHG85_08895	COG2972	Histidine kinase
FHG85_08905	COG4206	TonB-dependent receptor
FHG85_08905	COG1629	transport
FHG85_08920	COG1595	DNA-templated transcription, initiation
FHG85_08925	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FHG85_08930	COG4770	biotin carboxylase activity
FHG85_08940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FHG85_08945	COG0346	lactoylglutathione lyase activity
FHG85_08960	COG1480	7TM receptor with intracellular HD hydrolase
FHG85_08965	COG0617	tRNA 3'-terminal CCA addition
FHG85_08965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHG85_08965	COG0517	IMP dehydrogenase activity
FHG85_08975	COG0315	cyclic pyranopterin monophosphate synthase activity
FHG85_08975	COG0521	Mo-molybdopterin cofactor biosynthetic process
FHG85_08980	COG0315	cyclic pyranopterin monophosphate synthase activity
FHG85_08985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FHG85_08990	COG0303	'Molybdopterin
FHG85_09005	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHG85_09020	COG1629	transport
FHG85_09045	COG1629	transport
FHG85_09055	COG4771	TonB-dependent receptor
FHG85_09060	COG1595	DNA-templated transcription, initiation
FHG85_09075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FHG85_09090	COG2264	protein methyltransferase activity
FHG85_09095	COG0149	triose-phosphate isomerase activity
FHG85_09100	COG0601	transmembrane transport
FHG85_09105	COG3956	TIGRFAM MazG family protein
FHG85_09115	COG1702	phosphate starvation-inducible protein PhoH
FHG85_09120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FHG85_09135	COG1388	LysM domain
FHG85_09135	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHG85_09140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHG85_09145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FHG85_09150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHG85_09155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FHG85_09160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FHG85_09165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FHG85_09170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FHG85_09175	COG0681	Belongs to the peptidase S26 family
FHG85_09185	COG1012	belongs to the aldehyde dehydrogenase family
FHG85_09190	COG2183	response to ionizing radiation
FHG85_09195	COG0840	transmembrane signaling receptor activity
FHG85_09200	COG1193	negative regulation of DNA recombination
FHG85_09215	COG2884	Cell division ATP-binding protein ftsE
FHG85_09240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FHG85_09255	COG3850	Histidine kinase
FHG85_09255	COG4999	Histidine kinase
FHG85_09255	COG2205	protein histidine kinase activity
FHG85_09255	COG3437	response regulator, receiver
FHG85_09260	COG4717	serine-type aminopeptidase activity
FHG85_09265	COG0424	maF-like protein
FHG85_09275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FHG85_09290	COG2086	electron transfer activity
FHG85_09295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FHG85_09300	COG2181	nitrate reductase activity
FHG85_09300	COG0247	lactate metabolic process
FHG85_09305	COG2181	nitrate reductase activity
FHG85_09305	COG0247	lactate metabolic process
FHG85_09310	COG1960	acyl-CoA dehydrogenase activity
FHG85_09320	COG2205	protein histidine kinase activity
FHG85_09320	COG0784	Response regulator, receiver
FHG85_09340	COG2169	Transcriptional regulator
FHG85_09370	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FHG85_09375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FHG85_09385	COG1629	transport
FHG85_09385	COG4206	TonB-dependent receptor
FHG85_09395	COG1592	Rubrerythrin
FHG85_09405	COG0514	ATP-dependent DNA helicase (RecQ)
FHG85_09415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHG85_09435	COG1022	Amp-dependent synthetase and ligase
FHG85_09455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHG85_09460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FHG85_09500	COG2502	aspartate--ammonia ligase
FHG85_09520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHG85_09530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHG85_09545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FHG85_09560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHG85_09565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FHG85_09570	COG2045	Belongs to the ComB family
FHG85_09575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FHG85_09585	COG1366	Belongs to the anti-sigma-factor antagonist family
FHG85_09600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHG85_09635	COG0613	PHP domain protein
FHG85_09665	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FHG85_09670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FHG85_09680	COG3842	ATPase activity
FHG85_09685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FHG85_09690	COG0725	ABC transporter, periplasmic molybdate-binding protein
FHG85_09700	COG3123	guanosine phosphorylase activity
FHG85_09705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHG85_09755	COG1136	(ABC) transporter
FHG85_09755	COG0577	efflux transmembrane transporter activity
FHG85_09760	COG1136	(ABC) transporter
FHG85_09820	COG0525	valine-tRNA ligase activity
FHG85_09825	COG0288	reversible hydration of carbon dioxide
FHG85_09835	COG0439	Biotin carboxylase
FHG85_09860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FHG85_09870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHG85_09880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHG85_09920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FHG85_09920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FHG85_09925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FHG85_09930	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHG85_09935	COG0564	pseudouridine synthase activity
FHG85_09940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FHG85_09945	COG0443	Heat shock 70 kDa protein
FHG85_09955	COG1404	Belongs to the peptidase S8 family
FHG85_09960	COG1570	exodeoxyribonuclease VII activity
FHG85_09965	COG5002	protein histidine kinase activity
FHG85_09970	COG2202	Pas domain
FHG85_09970	COG2205	protein histidine kinase activity
FHG85_09975	COG1722	exodeoxyribonuclease VII activity
FHG85_10010	COG0747	negative chemotaxis
FHG85_10030	COG3850	Histidine kinase
FHG85_10030	COG5002	protein histidine kinase activity
FHG85_10050	COG0463	Glycosyl transferase, family 2
FHG85_10050	COG1216	Glycosyl transferase, family 2
FHG85_10055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHG85_10060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FHG85_10065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHG85_10070	COG0159	tryptophan synthase activity
FHG85_10075	COG0133	tryptophan synthase activity
FHG85_10080	COG0135	phosphoribosylanthranilate isomerase activity
FHG85_10085	COG0134	indole-3-glycerol-phosphate synthase activity
FHG85_10090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FHG85_10100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHG85_10110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHG85_10115	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHG85_10120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FHG85_10125	COG0710	3-dehydroquinate dehydratase activity
FHG85_10130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FHG85_10135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FHG85_10140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FHG85_10150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FHG85_10150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHG85_10150	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_10150	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHG85_10155	COG3275	phosphorelay sensor kinase activity
FHG85_10170	COG1943	Transposase
FHG85_10195	COG1196	nuclear chromosome segregation
FHG85_10200	COG2852	Protein conserved in bacteria
FHG85_10230	COG1506	peptidase
FHG85_10230	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_10235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHG85_10245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FHG85_10265	COG4864	UPF0365 protein
FHG85_10310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FHG85_10315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FHG85_10320	COG0284	orotidine-5'-phosphate decarboxylase activity
FHG85_10325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FHG85_10330	COG2234	aminopeptidase activity
FHG85_10350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FHG85_10360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FHG85_10365	COG1185	polyribonucleotide nucleotidyltransferase activity
FHG85_10370	COG1505	serine-type exopeptidase activity
FHG85_10375	COG1428	Deoxynucleoside kinase
FHG85_10390	COG0045	succinate-CoA ligase (ADP-forming) activity
FHG85_10405	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FHG85_10405	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FHG85_10410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHG85_10415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FHG85_10425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHG85_10435	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FHG85_10455	COG0463	Glycosyl transferase, family 2
FHG85_10470	COG1629	transport
FHG85_10475	COG0702	epimerase
FHG85_10505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FHG85_10515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHG85_10545	COG1355	regulation of microtubule-based process
FHG85_10590	COG2205	protein histidine kinase activity
FHG85_10595	COG0745	RESPONSE REGULATOR receiver
FHG85_10605	COG0459	protein refolding
FHG85_10610	COG1610	YqeY-like protein
FHG85_10620	COG1272	protein, Hemolysin III
FHG85_10655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FHG85_10680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHG85_10680	COG2207	Transcriptional regulator
FHG85_10705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FHG85_10725	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FHG85_10730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHG85_10735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FHG85_10740	COG0193	aminoacyl-tRNA hydrolase activity
FHG85_10745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FHG85_10760	COG3142	Participates in the control of copper homeostasis
FHG85_10770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FHG85_10775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FHG85_10780	COG4770	biotin carboxylase activity
FHG85_10785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FHG85_10795	COG0343	queuine tRNA-ribosyltransferase activity
FHG85_10800	COG0101	tRNA pseudouridine synthase activity
FHG85_10815	COG0463	Glycosyl transferase, family 2
FHG85_10820	COG0778	Nitroreductase
FHG85_10825	COG1418	mRNA catabolic process
FHG85_10890	COG0481	GTPase activity
FHG85_10905	COG1160	GTP binding
FHG85_10910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHG85_10915	COG1187	pseudouridine synthase activity
FHG85_10920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FHG85_10930	COG1136	(ABC) transporter
FHG85_10960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHG85_10965	COG0798	PFAM Bile acid sodium symporter
FHG85_10980	COG2205	protein histidine kinase activity
FHG85_10980	COG0784	Response regulator, receiver
FHG85_10985	COG0259	pyridoxamine-phosphate oxidase activity
FHG85_11005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FHG85_11010	COG4191	Histidine kinase
FHG85_11045	COG1309	transcriptional regulator
FHG85_11055	COG0513	Belongs to the DEAD box helicase family
FHG85_11065	COG1595	DNA-templated transcription, initiation
FHG85_11070	COG0357	Ribosomal RNA small subunit methyltransferase G
FHG85_11075	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FHG85_11080	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FHG85_11085	COG0515	serine threonine protein kinase
FHG85_11085	COG2815	serine threonine protein kinase
FHG85_11095	COG0564	pseudouridine synthase activity
FHG85_11115	COG1752	Esterase of the alpha-beta hydrolase superfamily
FHG85_11120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHG85_11135	COG0776	regulation of translation
FHG85_11140	COG1530	ribonuclease E activity
FHG85_11145	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FHG85_11150	COG3537	Alpha-1,2-mannosidase
FHG85_11165	COG1940	carbohydrate kinase activity
FHG85_11175	COG1609	Transcriptional regulator
FHG85_11205	COG0252	asparaginase activity
FHG85_11210	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHG85_11220	COG1283	sodium-dependent phosphate transmembrane transporter activity
FHG85_11225	COG4232	protein-disulfide reductase activity
FHG85_11230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FHG85_11235	COG1012	belongs to the aldehyde dehydrogenase family
FHG85_11245	COG2832	Protein of unknown function (DUF454)
FHG85_11250	COG1181	Belongs to the D-alanine--D-alanine ligase family
FHG85_11265	COG1473	amidohydrolase
FHG85_11270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHG85_11275	COG3292	Two component regulator propeller
FHG85_11275	COG2205	protein histidine kinase activity
FHG85_11275	COG0745	RESPONSE REGULATOR receiver
FHG85_11280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FHG85_11285	COG0148	phosphopyruvate hydratase activity
FHG85_11290	COG0203	ribosomal protein L17
FHG85_11295	COG0202	RNA polymerase activity
FHG85_11300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FHG85_11305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FHG85_11310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FHG85_11315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FHG85_11320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FHG85_11335	COG0200	Binds to the 23S rRNA
FHG85_11340	COG1841	ribosomal large subunit assembly
FHG85_11345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FHG85_11350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FHG85_11355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FHG85_11360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FHG85_11365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHG85_11370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FHG85_11375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FHG85_11380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FHG85_11385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FHG85_11390	COG0255	Belongs to the universal ribosomal protein uL29 family
FHG85_11395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FHG85_11400	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FHG85_11405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FHG85_11410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FHG85_11415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FHG85_11420	COG0089	rRNA binding
FHG85_11425	COG0088	Forms part of the polypeptide exit tunnel
FHG85_11430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FHG85_11435	COG0051	transcription antitermination factor activity, RNA binding
FHG85_11440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHG85_11445	COG0049	tRNA binding
FHG85_11450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FHG85_11455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHG85_11460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FHG85_11465	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
FHG85_11515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHG85_11515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHG85_11520	COG0195	Participates in both transcription termination and antitermination
FHG85_11525	COG0779	Required for maturation of 30S ribosomal subunits
FHG85_11530	COG0438	transferase activity, transferring glycosyl groups
FHG85_11535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHG85_11540	COG3591	Belongs to the peptidase S1B family
FHG85_11570	COG5002	protein histidine kinase activity
FHG85_11570	COG2205	protein histidine kinase activity
FHG85_11570	COG0784	Response regulator, receiver
FHG85_11590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHG85_11600	COG4953	penicillin-binding protein 1C
FHG85_11605	COG2373	Large extracellular alpha-helical protein
FHG85_11615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHG85_11615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHG85_11655	COG2171	N-acyltransferase activity
FHG85_11660	COG3959	Transketolase, thiamine diphosphate binding domain
FHG85_11670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHG85_11695	COG2166	iron-sulfur cluster assembly
FHG85_11700	COG2151	metal-sulfur cluster biosynthetic enzyme
FHG85_11720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FHG85_11725	COG0436	Aminotransferase
FHG85_11745	COG2204	response regulator
FHG85_11775	COG2205	protein histidine kinase activity
FHG85_11795	COG1695	Transcriptional regulator
FHG85_11810	COG1696	Membrane protein involved in D-alanine export
FHG85_11825	COG1393	Belongs to the ArsC family
FHG85_11835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FHG85_11835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FHG85_11840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHG85_11845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FHG85_11850	COG1968	undecaprenyl-diphosphatase activity
FHG85_11860	COG2177	Part of the ABC transporter FtsEX involved in
FHG85_11870	COG0423	glycine-tRNA ligase activity
FHG85_11885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FHG85_11890	COG4948	Mandelate Racemase Muconate Lactonizing
FHG85_11895	COG3250	beta-galactosidase activity
FHG85_11910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_11915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FHG85_11915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FHG85_11920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FHG85_11930	COG1475	DNA binding
FHG85_11935	COG1192	Involved in chromosome partitioning
FHG85_11940	COG1597	lipid kinase activity
FHG85_11950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FHG85_11955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FHG85_11960	COG2211	Major facilitator Superfamily
FHG85_11990	COG0175	sulfate reduction
FHG85_12005	COG0840	transmembrane signaling receptor activity
FHG85_12020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHG85_12025	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FHG85_12025	COG3264	Mechanosensitive ion channel
FHG85_12045	COG1011	Hydrolase
FHG85_12065	COG1271	oxidase subunit
FHG85_12070	COG1294	oxidase, subunit
FHG85_12075	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FHG85_12080	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHG85_12085	COG1183	phosphatidylcholine synthase activity
FHG85_12090	COG0671	phosphoesterase, PA-phosphatase related
FHG85_12095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHG85_12100	COG0563	adenylate kinase activity
FHG85_12110	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FHG85_12135	COG4989	oxidoreductase activity
FHG85_12160	COG0402	S-adenosylhomocysteine deaminase activity
FHG85_12165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHG85_12165	COG0731	radical SAM domain protein
FHG85_12195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHG85_12200	COG0416	fatty acid biosynthetic process
FHG85_12205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FHG85_12215	COG1217	gtp-binding protein TYPA
FHG85_12235	COG1428	Deoxynucleoside kinase
FHG85_12245	COG0156	8-amino-7-oxononanoate synthase activity
FHG85_12255	COG1214	PFAM Peptidase M22, glycoprotease
FHG85_12340	COG3179	chitinase
FHG85_12350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHG85_12385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHG85_12405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FHG85_12425	COG1629	transport
FHG85_12435	COG0698	ribose 5-phosphate isomerase
FHG85_12440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHG85_12460	COG2205	protein histidine kinase activity
FHG85_12460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHG85_12470	COG1381	Involved in DNA repair and RecF pathway recombination
FHG85_12480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FHG85_12500	COG3829	transcription factor binding
FHG85_12500	COG3290	protein histidine kinase activity
FHG85_12510	COG2204	response regulator
FHG85_12545	COG1595	DNA-templated transcription, initiation
FHG85_12550	COG0151	Belongs to the GarS family
FHG85_12560	COG2176	DNA-directed DNA polymerase activity
FHG85_12570	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FHG85_12580	COG0720	synthase
FHG85_12590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHG85_12620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHG85_12625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHG85_12640	COG0793	Belongs to the peptidase S41A family
FHG85_12645	COG2131	deaminase
FHG85_12655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FHG85_12695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHG85_12705	COG0012	GTP binding
FHG85_12710	COG2198	Histidine kinase
FHG85_12710	COG0784	Response regulator, receiver
FHG85_12710	COG2205	protein histidine kinase activity
FHG85_12715	COG0009	L-threonylcarbamoyladenylate synthase
FHG85_12725	COG0463	Glycosyl transferase, family 2
FHG85_12730	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FHG85_12735	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FHG85_12750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FHG85_12755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHG85_12760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FHG85_12765	COG0571	ribonuclease III activity
FHG85_12775	COG0840	transmembrane signaling receptor activity
FHG85_12805	COG1730	sister chromatid segregation
FHG85_12825	COG0006	proline dipeptidase activity
FHG85_12840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FHG85_12860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FHG85_12865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FHG85_12905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHG85_12910	COG2356	endonuclease I
FHG85_12915	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHG85_12925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FHG85_12930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FHG85_12940	COG2431	L-lysine efflux transmembrane transporter activity
FHG85_12945	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FHG85_12955	COG1522	sequence-specific DNA binding
FHG85_12975	COG1490	D-aminoacyl-tRNA deacylase activity
FHG85_13000	COG0739	heme binding
FHG85_13005	COG0826	peptidase U32
FHG85_13015	COG0859	PFAM glycosyl transferase family 9
FHG85_13020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHG85_13025	COG1162	GTPase activity
FHG85_13035	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FHG85_13055	COG1283	sodium-dependent phosphate transmembrane transporter activity
FHG85_13060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FHG85_13065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FHG85_13070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHG85_13075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FHG85_13080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHG85_13085	COG0356	it plays a direct role in the translocation of protons across the membrane
FHG85_13130	COG5002	protein histidine kinase activity
FHG85_13135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FHG85_13140	COG0594	ribonuclease P activity
FHG85_13155	COG0322	excinuclease ABC activity
FHG85_13160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FHG85_13165	COG0445	tRNA wobble uridine modification
FHG85_13170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA