locus-tag class description TepRe1_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) TepRe1_0003 ENOG4105WQ3 Rna-binding protein TepRe1_0004 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) TepRe1_0007 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) TepRe1_0008 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) TepRe1_0009 ENOG4105CXN decarboxylase TepRe1_0010 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) TepRe1_0011 ENOG4105X0R protein from nitrogen regulatory protein P-II TepRe1_0012 ENOG4105XVJ Protein of unknown function (DUF327) TepRe1_0014 ENOG4105MA4 psp1 domain protein TepRe1_0016 ENOG4108JUB Transcriptional regulator TepRe1_0017 ENOG4105MWK D-amino acid dehydrogenase, small subunit TepRe1_0018 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) TepRe1_0020 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) TepRe1_0033 ENOG4105II7 pyrroline-5-carboxylate reductase TepRe1_0034 ENOG4105KRN Transcriptional regulator, abrb family TepRe1_0037 ENOG4108IMY Transcriptional regulator TepRe1_0038 ENOG4105DC7 peptidase M24 TepRe1_0040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component TepRe1_0041 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component TepRe1_0043 ENOG4108JQ7 (ABC) transporter TepRe1_0044 ENOG4105C6N Formate acetyltransferase TepRe1_0045 ENOG4105F1A Pyruvate formate-lyase TepRe1_0046 ENOG4105C26 Dehydrogenase TepRe1_0049 ENOG4105C6Z Gluconate TepRe1_0052 ENOG4105CK1 PTS System TepRe1_0053 ENOG4105CS2 ec 3.2.1.21 TepRe1_0054 ENOG4105VCP PTS System TepRe1_0058 ENOG4105CFC Transporter TepRe1_0060 ENOG4105CH2 amidohydrolase TepRe1_0067 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein TepRe1_0070 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) TepRe1_0073 ENOG4105F8V Hydrolase, tatD family TepRe1_0075 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) TepRe1_0076 ENOG4108XRC Protein of unknown function (DUF458) TepRe1_0078 ENOG4105XFA sporulation peptidase YabG TepRe1_0079 ENOG4105JFG SpoIID LytB domain protein TepRe1_0080 ENOG4105W42 Veg protein TepRe1_0082 ENOG4105K4I Scp-like extracellular TepRe1_0085 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) TepRe1_0086 ENOG4105DRR Transcriptional regulator, GntR family TepRe1_0087 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) TepRe1_0088 ENOG4105DFT pur operon repressor TepRe1_0089 ENOG4105K4W Could be involved in septation (By similarity) TepRe1_0090 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) TepRe1_0091 ENOG4105C5T Phosphoribosyl pyrophosphate synthase TepRe1_0092 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) TepRe1_0093 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) TepRe1_0097 ENOG4105CBX hi0933 family TepRe1_0098 ENOG4108IMY Transcriptional regulator TepRe1_0100 ENOG4105K63 Thioredoxin TepRe1_0101 ENOG4105DSE periplasmic solute binding protein TepRe1_0102 ENOG4105FDK ABC transporter TepRe1_0104 ENOG4105N80 Ferric uptake regulator, Fur family TepRe1_0111 ENOG4105ZHF CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity) TepRe1_0112 ENOG4107YT1 Glutamate mutase subunit sigma TepRe1_0114 ENOG4105DJI Methylaspartate mutase, E subunit TepRe1_0115 ENOG4105DV9 Methylaspartate ammonia-lyase TepRe1_0118 ENOG4105PTM secreted protein TepRe1_0134 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit TepRe1_0135 ENOG410835K Tripartite ATP-Independent Periplasmic transporter DctQ TepRe1_0136 ENOG4105CG6 trap dicarboxylate transporter dctm subunit TepRe1_0143 ENOG4108JUB Transcriptional regulator TepRe1_0144 ENOG4105DFM M18 family aminopeptidase TepRe1_0147 ENOG4108SAX Membrane TepRe1_0148 ENOG4108JEB The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) TepRe1_0149 ENOG4105NBU tryptophan transport protein TepRe1_0154 ENOG4107SDT Homocitrate synthase TepRe1_0155 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_0156 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) TepRe1_0157 ENOG4105DBK s4 domain protein TepRe1_0159 ENOG4105G6Z alkaline phosphatase TepRe1_0161 ENOG4105KME endoribonuclease L-psp TepRe1_0162 ENOG4105C7B Threonine dehydratase TepRe1_0163 ENOG410667J hydrolase TepRe1_0164 ENOG4105UQX Mate efflux family protein TepRe1_0167 ENOG4108JA2 transcriptioN-repair coupling factor TepRe1_0169 ENOG4108M14 stage v sporulation protein t TepRe1_0170 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase TepRe1_0171 ENOG4105CKP Polysaccharide Biosynthesis Protein TepRe1_0172 ENOG4105DXN mazG family TepRe1_0179 ENOG41060GV RNA binding s1 domain protein TepRe1_0181 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) TepRe1_0183 ENOG4105XPM ribosomal protein TepRe1_0184 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) TepRe1_0185 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) TepRe1_0186 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) TepRe1_0187 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) TepRe1_0188 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) TepRe1_0189 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) TepRe1_0190 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) TepRe1_0191 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) TepRe1_0192 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity TepRe1_0193 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) TepRe1_0194 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) TepRe1_0195 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) TepRe1_0197 ENOG41082SA 50s ribosomal protein l29 TepRe1_0198 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal TepRe1_0199 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) TepRe1_0200 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) TepRe1_0201 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits TepRe1_0202 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) TepRe1_0203 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) TepRe1_0204 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) TepRe1_0205 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) TepRe1_0206 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) TepRe1_0207 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) TepRe1_0208 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) TepRe1_0209 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) TepRe1_0210 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) TepRe1_0212 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) TepRe1_0213 ENOG41067V7 50S ribosomal protein L36 TepRe1_0214 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits TepRe1_0215 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) TepRe1_0216 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) TepRe1_0217 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) TepRe1_0218 ENOG4108ZT0 50S ribosomal protein l17 TepRe1_0219 ENOG4108JJB ABC transporter TepRe1_0220 ENOG4108JJB ABC transporter TepRe1_0221 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) TepRe1_0222 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) TepRe1_0223 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) TepRe1_0224 ENOG4108UJD 30S ribosomal protein S9 TepRe1_0225 ENOG4107QW8 radical SAM domain protein TepRe1_0226 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) TepRe1_0227 ENOG4105UQX Mate efflux family protein TepRe1_0230 ENOG4107T2D Phosphoribosylaminoimidazolesuccinocarboxamide synthase TepRe1_0231 ENOG4105C3M thioredoxin reductase TepRe1_0232 ENOG4105DBV ornithine carbamoyltransferase TepRe1_0234 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) TepRe1_0235 ENOG4105CRK lysyL-tRNA synthetase TepRe1_0236 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes TepRe1_0241 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) TepRe1_0247 ENOG4107U53 septum site-determining protein minD TepRe1_0247 ENOG4107U53 septum site-determining protein minD TepRe1_0248 ENOG4105VYW UPF0251 protein TepRe1_0254 ENOG4105D17 glycoside hydrolase, family 3 domain protein TepRe1_0256 ENOG4105CE1 Ferrous iron transport protein b TepRe1_0260 ENOG41080HT Transcriptional regulator, arsr family TepRe1_0262 ENOG4108SHJ s-layer protein TepRe1_0269 ENOG4105D2N Aldolase TepRe1_0270 ENOG4105CPQ Dehydrogenase TepRe1_0271 ENOG4105F3R pts system mannose fructose sorbose family iid TepRe1_0272 ENOG4105ETZ PTS System TepRe1_0273 ENOG4108IQ3 PTS system TepRe1_0280 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) TepRe1_0281 ENOG4108Z5V transcriptional regulator, merr family TepRe1_0282 ENOG4108UM1 dedA family TepRe1_0287 ENOG4105RYY domain protein TepRe1_0291 ENOG4108Q52 Methyltransferase cognate corrinoid protein TepRe1_0294 ENOG4108Q52 Methyltransferase cognate corrinoid protein TepRe1_0300 ENOG4108Q52 Methyltransferase cognate corrinoid protein TepRe1_0304 ENOG410908R Methenyltetrahydrofolate cyclohydrolase TepRe1_0305 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) TepRe1_0309 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) TepRe1_0310 ENOG4108Q52 Methyltransferase cognate corrinoid protein TepRe1_0311 ENOG4105FDP GntR family transcriptional regulator TepRe1_0312 ENOG4107GBW cellulosome anchoring protein cohesin TepRe1_0315 ENOG4105BZU Histidine kinase TepRe1_0317 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) TepRe1_0319 ENOG4105HKU nucleoside recognition domain-containing protein TepRe1_0320 ENOG4105HKU nucleoside recognition domain-containing protein TepRe1_0323 ENOG4105C8B TIGR00159 family TepRe1_0325 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) TepRe1_0326 ENOG4105C1A potassium transporter peripheral membrane TepRe1_0327 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) TepRe1_0329 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) TepRe1_0331 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein TepRe1_0333 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component TepRe1_0334 ENOG4108JQ6 ABC transporter TepRe1_0337 ENOG4105CNW domain protein TepRe1_0338 ENOG4105C59 p-type ATPase TepRe1_0339 ENOG4108UIN ybak prolyl-trna synthetase associated region TepRe1_0343 ENOG4105DGA Diaminopimelate dehydrogenase TepRe1_0344 ENOG4105UQX Mate efflux family protein TepRe1_0345 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) TepRe1_0346 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) TepRe1_0347 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor TepRe1_0348 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor TepRe1_0351 ENOG4105PW4 Sugar fermentation stimulation protein homolog TepRe1_0355 ENOG4107SJS nitrite reductase, (NAD(P)H) TepRe1_0356 ENOG4105VCQ rubredoxin TepRe1_0357 ENOG4105KY8 Rubrerythrin TepRe1_0358 ENOG4105CPF Cell wall formation (By similarity) TepRe1_0363 ENOG4108ZJI phenylacetic acid degradation protein TepRe1_0364 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) TepRe1_0369 ENOG4105VRS hydrolase family 18 TepRe1_0371 ENOG4105CDJ oxidoreductase FAD NAD(P)-binding domain protein TepRe1_0372 ENOG4105BZ8 glutamate synthase TepRe1_0375 ENOG4105CIZ coA-substrate-specific enzyme activase TepRe1_0376 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) TepRe1_0377 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit TepRe1_0383 ENOG4105CJN penicillin-binding protein TepRe1_0385 ENOG4108IV0 ABC, transporter TepRe1_0386 ENOG4105C0Z ABC transporter TepRe1_0387 ENOG4105CF8 branched-chain amino acid ABC transporter, permease TepRe1_0388 ENOG4105C32 Amino acid ABC transporter (Permease) TepRe1_0391 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) TepRe1_0392 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) TepRe1_0396 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) TepRe1_0400 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_0401 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_0406 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin TepRe1_0409 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) TepRe1_0417 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC TepRe1_0418 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) TepRe1_0419 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family TepRe1_0420 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family TepRe1_0421 ENOG4105F4R Transcriptional regulator mode TepRe1_0423 ENOG4105EHG Permease protein TepRe1_0424 ENOG4105E0A ABC, transporter TepRe1_0425 ENOG4105S10 periplasmic binding protein TepRe1_0426 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) TepRe1_0427 ENOG4105VFE sira family TepRe1_0428 ENOG4105C3J Cysteine desulfurase TepRe1_0434 ENOG4107W7X Aldolase TepRe1_0435 ENOG4105C5I Dehydrogenase TepRe1_0438 ENOG4105C28 cystathionine TepRe1_0439 ENOG4105CMG Carbohydrate kinase TepRe1_0441 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component TepRe1_0443 ENOG4105C3U ABC transporter TepRe1_0444 ENOG4108JQ7 (ABC) transporter TepRe1_0445 ENOG4107QSE Dipeptidase TepRe1_0446 ENOG4105CEM UPF0597 protein TepRe1_0448 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) TepRe1_0449 ENOG4108JJB ABC transporter TepRe1_0450 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) TepRe1_0451 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein TepRe1_0452 ENOG41081F0 Precorrin-8x methylmutase TepRe1_0455 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase TepRe1_0457 ENOG4105CIA precorrin-4 C(11)-methyltransferase TepRe1_0458 ENOG4108P62 biosynthesis protein (CbiG) TepRe1_0459 ENOG4105E4R Precorrin-3B C17-methyltransferase TepRe1_0461 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) TepRe1_0462 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) TepRe1_0464 ENOG4105D52 delta-aminolevulinic acid dehydratase TepRe1_0465 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) TepRe1_0466 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase TepRe1_0467 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) TepRe1_0468 ENOG4105CE4 GlcNAc 6-P deacetylase TepRe1_0469 ENOG4106N3A copper homeostasis protein cutc TepRe1_0470 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) TepRe1_0472 ENOG4105EQD regulatoR TepRe1_0473 ENOG4105C2F Histidine kinase TepRe1_0474 ENOG4105C2J ABC transporter TepRe1_0475 ENOG4105C2J ABC transporter TepRe1_0476 ENOG4105CNN ABC, transporter TepRe1_0481 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) TepRe1_0482 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) TepRe1_0483 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) TepRe1_0485 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) TepRe1_0486 ENOG4108ESY Metal dependent phosphohydrolase TepRe1_0488 ENOG4108ME1 Peptidase M55 D-aminopeptidase TepRe1_0489 ENOG4105CD3 dihydroorotase TepRe1_0490 ENOG4105K8N protein family UPF0079, ATPase TepRe1_0491 ENOG41072GX Peptidase M22 Glycoprotease TepRe1_0492 ENOG410801F ribosomal-protein-alanine acetyltransferase TepRe1_0493 ENOG4108S4C acetyltransferase TepRe1_0494 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) TepRe1_0495 ENOG4105C5H ABC transporter TepRe1_0498 ENOG4105C6K Malic enzyme TepRe1_0501 ENOG4108SHJ s-layer protein TepRe1_0502 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator TepRe1_0503 ENOG4105KT7 mgtC SapB transporter TepRe1_0504 ENOG4105D00 flagellar biosynthetic protein flhB TepRe1_0506 ENOG4105C7N Xanthine uracil vitamin C permease TepRe1_0509 ENOG4107WUB V-type ATPase 116 kDa subunit TepRe1_0510 ENOG410839E ATP synthase, F0 subunit c TepRe1_0513 ENOG4108JIQ Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) TepRe1_0514 ENOG4108JIP Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity) TepRe1_0515 ENOG4106C6A Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) TepRe1_0532 ENOG4105C79 DNA protecting protein DprA TepRe1_0542 ENOG4105E5G Alpha beta hydrolase fold TepRe1_0546 ENOG4105EE0 oxidoreductase TepRe1_0547 ENOG4108XIB electron transport protein ysaA TepRe1_0548 ENOG4105CJG carbon-monoxide dehydrogenase catalytic subunit TepRe1_0549 ENOG41080XS Cobyrinic acid ac-diamide synthase TepRe1_0550 ENOG4105CKU formyltetrahydrofolate synthetase TepRe1_0552 ENOG410908R Methenyltetrahydrofolate cyclohydrolase TepRe1_0553 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) TepRe1_0555 ENOG4105SYT Methylenetetrahydrofolate reductase TepRe1_0558 ENOG4106HYN CO dehydrogenase acetyl-CoA synthase delta subunit TepRe1_0559 ENOG4105EYX Acetyl-CoA decarbonylase synthase complex subunit gamma TepRe1_0560 ENOG4107VP5 methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase TepRe1_0561 ENOG4105E8X CO dehydrogenase acetyl-CoA synthase complex beta subunit TepRe1_0562 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) TepRe1_0567 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) TepRe1_0568 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator TepRe1_0569 ENOG41062EX TepRe1_0570 ENOG410641M TepRe1_0571 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) TepRe1_0572 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A TepRe1_0575 ENOG4108JUA Transcriptional regulator TepRe1_0576 ENOG4108NVR Methyl-accepting chemotaxis TepRe1_0577 ENOG4105CMT Dihydroxyacetone kinase TepRe1_0579 ENOG4105VDH Dihydroxyacetone kinase TepRe1_0581 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme TepRe1_0583 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) TepRe1_0585 ENOG4108UVJ appr-1-p processing domain protein TepRe1_0586 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase TepRe1_0587 ENOG4105CJT Mannose-1-phosphate guanylyltransferase TepRe1_0588 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR TepRe1_0593 ENOG4105C3G gtp-binding protein TepRe1_0596 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) TepRe1_0598 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase TepRe1_0599 ENOG4108U5N UPF0316 protein TepRe1_0601 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) TepRe1_0602 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) TepRe1_0604 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation TepRe1_0605 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) TepRe1_0606 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) TepRe1_0607 ENOG4108IUQ atp-dependent protease TepRe1_0608 ENOG4105VRS hydrolase family 18 TepRe1_0610 ENOG4107QSE Dipeptidase TepRe1_0611 ENOG4105KGF protein, YerC YecD TepRe1_0615 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family TepRe1_0617 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) TepRe1_0618 ENOG4105DT3 PTS system, galactitol-specific IIc component TepRe1_0619 ENOG4105CPQ Dehydrogenase TepRe1_0620 ENOG4105CPQ Dehydrogenase TepRe1_0636 ENOG4107RHR regulatoR TepRe1_0638 ENOG410787A Pts system, glucitol sorbitol-specific TepRe1_0639 ENOG4105DZY Pts system, glucitol sorbitol-specific TepRe1_0642 ENOG4107RUY (E1 component), alpha subunit TepRe1_0643 ENOG4105CPP Dehydrogenase, E1 component TepRe1_0646 ENOG4108IJ0 Aspartate ammonia-lyase TepRe1_0647 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) TepRe1_0648 ENOG4105ETE Transcriptional regulator (LacI family TepRe1_0649 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator TepRe1_0650 ENOG4105C2J ABC transporter TepRe1_0651 ENOG4105CNN ABC, transporter TepRe1_0653 ENOG4107W9I Creatinine amidohydrolase TepRe1_0654 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) TepRe1_0655 ENOG4107S8A protein TIM barrel TepRe1_0660 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) TepRe1_0661 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) TepRe1_0663 ENOG4105ECC imidazole-glycerol-phosphate dehydratase TepRe1_0664 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase TepRe1_0665 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) TepRe1_0666 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase TepRe1_0668 ENOG4108UH6 UPF0754 membrane protein TepRe1_0668 ENOG4108UH6 UPF0754 membrane protein TepRe1_0669 ENOG4105C22 threonyL-tRNA synthetase TepRe1_0670 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) TepRe1_0671 ENOG4105VJV 50s ribosomal protein L35 TepRe1_0672 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) TepRe1_0673 ENOG4105CZN Potassium uptake protein TepRe1_0675 ENOG4108RWN rrna methyltransferase TepRe1_0677 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) TepRe1_0678 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) TepRe1_0679 ENOG410687F Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) TepRe1_0680 ENOG4105DCG PHP domain protein TepRe1_0681 ENOG4105C98 muts2 protein TepRe1_0684 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) TepRe1_0689 ENOG4105EQI Metal Dependent Phosphohydrolase TepRe1_0690 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) TepRe1_0691 ENOG41086CI Bifunctional phosphoglucose phosphomannose isomerase TepRe1_0692 ENOG4105DCG PHP domain protein TepRe1_0693 ENOG4105F0I Aminotransferase TepRe1_0695 ENOG4105D4A Cell wall formation (By similarity) TepRe1_0700 ENOG4105CJW magnesium transporter TepRe1_0701 ENOG4105CJW magnesium transporter TepRe1_0702 ENOG41084CE UPF0342 protein TepRe1_0703 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) TepRe1_0704 ENOG4105CHW UPF0052 protein TepRe1_0705 ENOG4105CIE May be required for sporulation (By similarity) TepRe1_0706 ENOG4105KRI phosphocarrier protein (HPr TepRe1_0708 ENOG4105C0B DNA polymerase III (alpha subunit) TepRe1_0710 ENOG4105CTQ phosphohexokinase TepRe1_0712 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 TepRe1_0714 ENOG4105EPR degv family TepRe1_0717 ENOG4105ETE Transcriptional regulator (LacI family TepRe1_0718 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) TepRe1_0720 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) TepRe1_0722 ENOG4105C2J ABC transporter TepRe1_0723 ENOG4105CNN ABC, transporter TepRe1_0725 ENOG4107QP6 Xylose isomerase domain protein TIM barrel TepRe1_0726 ENOG4105E2R ROK family TepRe1_0727 ENOG4105DZS Phenylacetate-CoA ligase TepRe1_0733 ENOG4108Z3G 3H domain protein TepRe1_0737 ENOG4105E1K spore germination protein TepRe1_0738 ENOG4105DF9 Lipoate-protein, ligase TepRe1_0739 ENOG4105KST dependent repressor TepRe1_0741 ENOG4105CE1 Ferrous iron transport protein b TepRe1_0742 ENOG4105DKQ ROK family TepRe1_0743 ENOG4105DKQ ROK family TepRe1_0744 ENOG4105D2N Aldolase TepRe1_0745 ENOG41086CI Bifunctional phosphoglucose phosphomannose isomerase TepRe1_0747 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator TepRe1_0748 ENOG4105C2J ABC transporter TepRe1_0749 ENOG4108HWV )-transporter TepRe1_0751 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) TepRe1_0769 ENOG4105F3H Histidine kinase TepRe1_0770 ENOG4105C6T cysteine synthase TepRe1_0772 ENOG4105C84 Histidine ammonia-lyase TepRe1_0773 ENOG4105CK7 Sodium proline symporter TepRe1_0774 ENOG4105CGP Urocanate hydratase TepRe1_0775 ENOG4105CCS Glutamate formiminotransferase TepRe1_0776 ENOG4105CI2 imidazolone-5-propionate hydrolase TepRe1_0777 ENOG410908R Methenyltetrahydrofolate cyclohydrolase TepRe1_0781 ENOG4105DIB Oligopeptide-binding protein TepRe1_0782 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component TepRe1_0783 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component TepRe1_0784 ENOG4105C3U ABC transporter TepRe1_0785 ENOG4108JQ7 (ABC) transporter TepRe1_0791 ENOG4107EF8 Glycosyl transferase (Group 1 TepRe1_0805 ENOG4108V0P LemA family TepRe1_0807 ENOG4105C22 threonyL-tRNA synthetase TepRe1_0808 ENOG4105VEQ Cold shock protein TepRe1_0818 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving TepRe1_0820 ENOG4105DUN Mediates zinc uptake. May also transport other divalent cations (By similarity) TepRe1_0821 ENOG41081UC Inherit from COG: Competence protein TepRe1_0825 ENOG4105E1Q flagellar hook-associated protein TepRe1_0826 ENOG4105DTJ flagellar hook-associated protein TepRe1_0828 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) TepRe1_0829 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) TepRe1_0849 ENOG4105C3G gtp-binding protein TepRe1_0857 ENOG4107RT6 flagellar hook-associated TepRe1_0858 ENOG4105MQ3 flagellar protein FliS TepRe1_0862 ENOG4105C28 cystathionine TepRe1_0863 ENOG4105DFD Na H antiporter TepRe1_0864 ENOG4107RVV histidinol phosphate phosphatase, hisj family TepRe1_0866 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer TepRe1_0867 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) TepRe1_0869 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) TepRe1_0874 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) TepRe1_0892 ENOG41086D8 Transcriptional regulator TepRe1_0901 ENOG4105CK6 Two component transcriptional regulator (Winged helix family TepRe1_0903 ENOG4105DA5 (ABC) transporter TepRe1_0907 ENOG4105C5H ABC transporter TepRe1_0915 ENOG4105DY9 regulatoR TepRe1_0922 ENOG4105D5G Transposase TepRe1_0962 ENOG4105DPZ Two component transcriptional regulator (Winged helix family TepRe1_0967 ENOG4105C8Y Acetylornithine aminotransferase TepRe1_0968 ENOG4105UQX Mate efflux family protein TepRe1_0969 ENOG41069ER domain protein TepRe1_0970 ENOG4105DZ1 carboxypeptidase TepRe1_0972 ENOG4108QY0 Membrane TepRe1_0974 ENOG4105Y5S NADH ubiquinone oxidoreductase, 24 kD TepRe1_0977 ENOG4108I5C dEAD DEAH box helicase TepRe1_0978 ENOG4107X2U Inherit from COG: Exonuclease-like protein TepRe1_0980 ENOG4105CVA phosphate TepRe1_0981 ENOG4105C8U phosphate abc transporter TepRe1_0982 ENOG4105E2Z phosphate ABC transporter (Permease TepRe1_0983 ENOG4105DPZ Two component transcriptional regulator (Winged helix family TepRe1_0984 ENOG4105BZU Histidine kinase TepRe1_0985 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) TepRe1_0986 ENOG4108UTW Plays a role in the regulation of phosphate uptake TepRe1_0987 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) TepRe1_0988 ENOG4105VI0 Pts system, glucitol sorbitol-specific TepRe1_0991 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) TepRe1_0995 ENOG4105CJ1 ABC, transporter TepRe1_0997 ENOG4105DFD Na H antiporter TepRe1_0999 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) TepRe1_1000 ENOG4105EHG Permease protein TepRe1_1001 ENOG4108YZT Adenosylcobinamide kinase TepRe1_1002 ENOG4105JZC GHMP kinase TepRe1_1003 ENOG4105CIH Imidazole acetol-phosphate transaminase TepRe1_1004 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) TepRe1_1005 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) TepRe1_1006 ENOG4105CVJ phosphoglycerate mutase TepRe1_1007 ENOG41083MR nifu domain-containing protein TepRe1_1011 ENOG4105JVQ RNA Polymerase TepRe1_1012 ENOG4108P49 AntiSigma factor TepRe1_1015 ENOG4105CCN Peptidase M56 TepRe1_1016 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) TepRe1_1017 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase TepRe1_1018 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) TepRe1_1021 ENOG4108IMY Transcriptional regulator TepRe1_1031 ENOG4105CDU Replicative dna helicase TepRe1_1035 ENOG4105KC4 UPF0296 protein TepRe1_1036 ENOG4108UUM single-stranded DNA-binding protein TepRe1_1046 ENOG4105IG6 Phage terminase, large subunit TepRe1_1068 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) TepRe1_1069 ENOG4105CY0 Metallo-Beta-Lactamase TepRe1_1070 ENOG41066FP Small acid-soluble spore protein I TepRe1_1071 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase TepRe1_1072 ENOG4105CHM Aminotransferase TepRe1_1073 ENOG4105VR9 phosphoribosylformylglycinamidine synthase TepRe1_1074 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I TepRe1_1075 ENOG4107QIK phosphoribosylformylglycinamidine synthase TepRe1_1077 ENOG4105CXB phosphoribosylaminoimidazole synthetase TepRe1_1078 ENOG4108V3E phosphoribosylglycinamide formyltransferase TepRe1_1079 ENOG4105DC1 bifunctional purine biosynthesis protein purh TepRe1_1080 ENOG4107QNG Phosphoribosylglycinamide synthetase TepRe1_1081 ENOG4108RAC Rubrerythrin TepRe1_1082 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) TepRe1_1084 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) TepRe1_1085 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 TepRe1_1086 ENOG4105TQK DNA polymerase iii, delta' subunit TepRe1_1087 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) TepRe1_1089 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) TepRe1_1092 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) TepRe1_1093 ENOG4105CSA Coproporphyrinogen iii oxidase TepRe1_1094 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) TepRe1_1095 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) TepRe1_1096 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ TepRe1_1097 ENOG4105CFG Acts as a chaperone (By similarity) TepRe1_1098 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) TepRe1_1099 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) TepRe1_1100 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) TepRe1_1101 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) TepRe1_1102 ENOG4107YU2 histidine triad (hIT) protein TepRe1_1103 ENOG4105VCC 30S ribosomal protein S21 TepRe1_1104 ENOG4105KTH gatB Yqey TepRe1_1105 ENOG4105F7J membrane-bound serine protease TepRe1_1106 ENOG4105DI5 UPF0365 protein TepRe1_1108 ENOG41068P3 sporulation protein YqfC TepRe1_1110 ENOG4105C9A Phoh family TepRe1_1111 ENOG4105CTJ Metal Dependent Phosphohydrolase TepRe1_1112 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) TepRe1_1114 ENOG4108R5T secreted protein TepRe1_1115 ENOG4108SAY Involved in DNA repair and RecF pathway recombination (By similarity) TepRe1_1117 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) TepRe1_1118 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) TepRe1_1119 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein TepRe1_1120 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) TepRe1_1121 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1123 ENOG4105EGD dinuclear metal center protein, YbgI family TepRe1_1125 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) TepRe1_1126 ENOG410828M hemerythrin-like, metal-binding protein TepRe1_1131 ENOG4108V6E Cell division protein mraZ TepRe1_1132 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) TepRe1_1133 ENOG41068JM cell division protein, FtsL TepRe1_1134 ENOG4105CJN penicillin-binding protein TepRe1_1135 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) TepRe1_1136 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) TepRe1_1137 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) TepRe1_1138 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) TepRe1_1139 ENOG4105CNI cell division protein FtsW TepRe1_1140 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) TepRe1_1141 ENOG4105DFU Cell wall formation (By similarity) TepRe1_1142 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) TepRe1_1145 ENOG4105K67 small basic protein TepRe1_1146 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) TepRe1_1147 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) TepRe1_1148 ENOG4105FFI sigma-e processing peptidase spoiiga TepRe1_1149 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1150 ENOG4105E65 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1152 ENOG4105WR5 sporulation protein, YlmC YmxH family TepRe1_1153 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) TepRe1_1154 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) TepRe1_1159 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) TepRe1_1160 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase TepRe1_1161 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) TepRe1_1162 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 TepRe1_1163 ENOG4105D1H recombination factor protein RarA TepRe1_1164 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) TepRe1_1165 ENOG4105KXX peptidase s58 dmpa TepRe1_1168 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein TepRe1_1169 ENOG4107RA1 nh(3)-dependent nad( ) synthetase TepRe1_1170 ENOG4105CDY transcriptional regulatory protein TepRe1_1172 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) TepRe1_1173 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) TepRe1_1174 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) TepRe1_1175 ENOG4105JFG SpoIID LytB domain protein TepRe1_1176 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) TepRe1_1178 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) TepRe1_1179 ENOG4105VIE preprotein translocase, subunit YajC TepRe1_1182 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) TepRe1_1183 ENOG4107SBW Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) TepRe1_1185 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) TepRe1_1186 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) TepRe1_1187 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) TepRe1_1188 ENOG4105EA8 2-Nitropropane dioxygenase TepRe1_1189 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase TepRe1_1190 ENOG4105CHR reductase TepRe1_1191 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) TepRe1_1192 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) TepRe1_1193 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) TepRe1_1194 ENOG4105MCT stage V sporulation protein S TepRe1_1195 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) TepRe1_1196 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) TepRe1_1197 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) TepRe1_1199 ENOG4105K5M 30s ribosomal protein S16 TepRe1_1201 ENOG4107Z8R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) TepRe1_1202 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) TepRe1_1203 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) TepRe1_1205 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) TepRe1_1206 ENOG4105VFF UPF0102 protein TepRe1_1207 ENOG4105C0P Mg chelatase subunit ChlI TepRe1_1208 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase TepRe1_1209 ENOG4105C79 DNA protecting protein DprA TepRe1_1210 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) TepRe1_1211 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) TepRe1_1212 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) TepRe1_1213 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) TepRe1_1214 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) TepRe1_1215 ENOG4105EUM DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity) TepRe1_1216 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) TepRe1_1217 ENOG4108ZC9 flagellar basal-body rod protein flgc TepRe1_1218 ENOG4105VQ0 flagellar hook-basal body complex protein fliE TepRe1_1219 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) TepRe1_1220 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) TepRe1_1226 ENOG410822I Flagellar hook capping protein TepRe1_1228 ENOG4105BZE flagellar hook protein, FlgE TepRe1_1230 ENOG4105E14 MotA TolQ exbB proton channel TepRe1_1231 ENOG4106VK6 Flagellar motor protein TepRe1_1233 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) TepRe1_1234 ENOG4105DD5 Flagellar motor switch protein TepRe1_1235 ENOG4107YTP response regulator receiver protein TepRe1_1237 ENOG4105CN7 Flagellar biosynthetic protein FliP TepRe1_1238 ENOG4105VS8 Flagellar biosynthetic protein fliq TepRe1_1239 ENOG4105D19 Role in flagellar biosynthesis (By similarity) TepRe1_1240 ENOG4105D00 flagellar biosynthetic protein flhB TepRe1_1241 ENOG4105D7B Flagellar biosynthesis protein flha TepRe1_1242 ENOG4105FZW flagellar biosynthesis regulator FlhF TepRe1_1245 ENOG4105CBS Chea signal transduction histidine kinase TepRe1_1246 ENOG4108V3W Chemotaxis protein, CheW TepRe1_1247 ENOG4107PHP CheC --inhibitor of MCP methylation TepRe1_1248 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) TepRe1_1249 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1253 ENOG4105C02 permease TepRe1_1254 ENOG4105CE9 30S ribosomal protein S2 TepRe1_1255 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) TepRe1_1256 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) TepRe1_1257 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) TepRe1_1259 ENOG4105KNE Phosphatidate cytidylyltransferase TepRe1_1260 ENOG4108REF Sporulation integral membrane protein ytvi TepRe1_1261 ENOG4105DZP Membrane-associated zinc metalloprotease TepRe1_1262 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) TepRe1_1263 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) TepRe1_1265 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) TepRe1_1266 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) TepRe1_1267 ENOG4105CHV Transcription elongation factor NusA TepRe1_1268 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination TepRe1_1269 ENOG4105VHM ribosomal protein TepRe1_1270 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) TepRe1_1272 ENOG4105SFS phosphoesterase RecJ domain protein TepRe1_1273 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) TepRe1_1274 ENOG4105DTN riboflavin biosynthesis protein ribF TepRe1_1275 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) TepRe1_1276 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) TepRe1_1277 ENOG4108ZJ4 polysaccharide deacetylase TepRe1_1278 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) TepRe1_1279 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) TepRe1_1281 ENOG4105CN5 Metallo-Beta-Lactamase TepRe1_1282 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit TepRe1_1284 ENOG4105CNU cell division protein FtsK TepRe1_1286 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) TepRe1_1288 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) TepRe1_1289 ENOG4105CEV competence damage-inducible protein TepRe1_1290 ENOG4105M7V 2'-5' rna ligase TepRe1_1291 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) TepRe1_1293 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) TepRe1_1297 ENOG4105D48 metallophosphoesterase TepRe1_1298 ENOG4105MCT stage V sporulation protein S TepRe1_1299 ENOG4105DB7 PHP domain protein TepRe1_1301 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein TepRe1_1302 ENOG4105DQU oxidoreductase, subunit beta TepRe1_1304 ENOG4105D82 Glutamate dehydrogenase TepRe1_1306 ENOG4105D5P Methylmalonyl-coA mutase TepRe1_1307 ENOG4105DJT lAO AO transport system ATPase TepRe1_1308 ENOG4108ZVT methylmalonyl-coA epimerase TepRe1_1309 ENOG4108HNZ carboxyl transferase TepRe1_1311 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein TepRe1_1312 ENOG4105D9Q decarboxylase (Beta subunit) TepRe1_1313 ENOG4107QSA Oxaloacetate decarboxylase TepRe1_1315 ENOG41073R8 VanW family TepRe1_1318 ENOG4108UN4 phage SPO1 DNA polymerase-related protein TepRe1_1319 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) TepRe1_1320 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) TepRe1_1321 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) TepRe1_1322 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) TepRe1_1323 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) TepRe1_1324 ENOG4106F1P AAA ATPase, central domain protein TepRe1_1325 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control TepRe1_1328 ENOG4105CXI aluminum resistance protein TepRe1_1329 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) TepRe1_1332 ENOG4105YAC TepRe1_1333 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) TepRe1_1336 ENOG4105CN9 Peptidase m42 family protein TepRe1_1337 ENOG4105CN9 Peptidase m42 family protein TepRe1_1338 ENOG4105CN9 Peptidase m42 family protein TepRe1_1339 ENOG4105BZU Histidine kinase TepRe1_1340 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) TepRe1_1341 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) TepRe1_1342 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) TepRe1_1345 ENOG4105CBX hi0933 family TepRe1_1347 ENOG4105E0A ABC, transporter TepRe1_1349 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) TepRe1_1351 ENOG4105FE9 pseudouridine synthase TepRe1_1354 ENOG4107CHF 5,6-aminomutase beta subunit TepRe1_1357 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) TepRe1_1358 ENOG4105C1Y Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity) TepRe1_1361 ENOG4105KBJ sporulation protein ytfj TepRe1_1364 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) TepRe1_1365 ENOG4105C31 Tryptophanyl-tRNA synthetase TepRe1_1366 ENOG4108Z4T Peptidase M50 TepRe1_1367 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) TepRe1_1368 ENOG4105CIZ coA-substrate-specific enzyme activase TepRe1_1373 ENOG4105CZ3 stage V sporulation protein ad TepRe1_1374 ENOG41090VF Stage v sporulation protein ac TepRe1_1375 ENOG41084UG Pfam:DUF1458 TepRe1_1377 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1378 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) TepRe1_1379 ENOG41082AN stage II sporulation protein TepRe1_1380 ENOG4105DZ1 carboxypeptidase TepRe1_1381 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) TepRe1_1382 ENOG4105MZ9 stage II sporulation protein m TepRe1_1385 ENOG4107QQR Sporulation TepRe1_1386 ENOG4105S1Z Stage IV sporulation protein B TepRe1_1387 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) TepRe1_1388 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) TepRe1_1389 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) TepRe1_1391 ENOG4105DX0 Hemolysin A TepRe1_1395 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) TepRe1_1396 ENOG4105M7K Involved in the transcription termination process (By similarity) TepRe1_1399 ENOG4105VBF alkaline shock protein TepRe1_1404 ENOG4105KQ4 Stage iii sporulation protein ad TepRe1_1405 ENOG4108CQH stage III sporulation protein AC TepRe1_1407 ENOG4105CD2 stage iii sporulation protein aa TepRe1_1409 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) TepRe1_1410 ENOG4105DC7 peptidase M24 TepRe1_1419 ENOG4107QHF type ii secretion system protein e TepRe1_1420 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase TepRe1_1421 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1422 ENOG4105CJN penicillin-binding protein TepRe1_1423 ENOG4105HHA aminodeoxychorismate lyase TepRe1_1426 ENOG4105I3K Ferric uptake regulator, Fur family TepRe1_1428 ENOG41085AS UPF0473 protein TepRe1_1429 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) TepRe1_1430 ENOG4107SET aldo keto reductase TepRe1_1431 ENOG4105VBH UPF0297 protein TepRe1_1432 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) TepRe1_1434 ENOG4105CUZ uba thif-type nad fad binding protein TepRe1_1435 ENOG4105C9M aspartyl-trna synthetase TepRe1_1436 ENOG4105C0H protease TepRe1_1438 ENOG4105C5X domain protein TepRe1_1439 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) TepRe1_1440 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) TepRe1_1441 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) TepRe1_1442 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) TepRe1_1445 ENOG41084P0 50S ribosomal protein L32 TepRe1_1448 ENOG4108IJ2 phosphate acetyltransferase TepRe1_1450 ENOG41063PX domain protein TepRe1_1451 ENOG4105H20 Sporulation integral membrane protein YlbJ TepRe1_1453 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) TepRe1_1454 ENOG4106H78 methyltransferase TepRe1_1457 ENOG4105DP4 dak2 domain fusion protein ylov TepRe1_1458 ENOG4108ZAA Alkaline-shock protein TepRe1_1461 ENOG4105DJV ribulose-phosphate 3-epimerase TepRe1_1462 ENOG4105D9P serine threonine protein kinase TepRe1_1463 ENOG4108ZF3 Phosphatase TepRe1_1464 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs TepRe1_1465 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B TepRe1_1467 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) TepRe1_1468 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) TepRe1_1469 ENOG4105C25 Primosomal protein n' TepRe1_1470 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase TepRe1_1471 ENOG41084KE Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) TepRe1_1472 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) TepRe1_1474 ENOG4105DSJ YicC domain protein TepRe1_1475 ENOG4105F23 Fibronectin-binding protein TepRe1_1476 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) TepRe1_1477 ENOG4105C34 Pseudouridine synthase TepRe1_1478 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) TepRe1_1479 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters TepRe1_1483 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) TepRe1_1484 ENOG4105DFA alanine racemase domain protein TepRe1_1486 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) TepRe1_1487 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) TepRe1_1489 ENOG41090I5 UPF0735 ACT domain-containing protein TepRe1_1491 ENOG4105CSM endonuclease III TepRe1_1492 ENOG4105CN1 protease TepRe1_1495 ENOG4105C19 ABC transporter TepRe1_1497 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) TepRe1_1500 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) TepRe1_1501 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) TepRe1_1503 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein TepRe1_1505 ENOG4105DIW FeS assembly protein SUFB TepRe1_1506 ENOG4108IUZ ABC transporter TepRe1_1508 ENOG4105C8T Leucyl-tRNA synthetase TepRe1_1510 ENOG4108KGH TRANSCRIPTIONal TepRe1_1511 ENOG4108WF2 Metal Dependent Phosphohydrolase TepRe1_1512 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) TepRe1_1513 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control TepRe1_1515 ENOG4105K46 50S ribosomal protein l27 TepRe1_1516 ENOG4105X36 (ribosomal) protein TepRe1_1519 ENOG4105MSI germination protein ypeb TepRe1_1525 ENOG4105C03 ribonuclease TepRe1_1531 ENOG4105CNI cell division protein FtsW TepRe1_1532 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) TepRe1_1533 ENOG41083CN Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) TepRe1_1534 ENOG4107QMS site-determining protein TepRe1_1535 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) TepRe1_1536 ENOG4105CJN penicillin-binding protein TepRe1_1538 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) TepRe1_1539 ENOG4105DFF Rod shape-determining protein mreb TepRe1_1540 ENOG4105W5Q DNA repair protein (RadC TepRe1_1541 ENOG4108Z03 MAF-like protein TepRe1_1545 ENOG4105EMN RNA polymerase sigma factor TepRe1_1551 ENOG4105CPQ Dehydrogenase TepRe1_1553 ENOG4105C6Z Gluconate TepRe1_1557 ENOG4107S2N Type III effector Hrp-dependent TepRe1_1558 ENOG4108JUB Transcriptional regulator TepRe1_1561 ENOG4105C8Q Methyl-accepting chemotaxis TepRe1_1563 ENOG4108JIC nucleoside recognition domain protein TepRe1_1564 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) TepRe1_1566 ENOG4105DCF alanine dehydrogenase TepRe1_1568 ENOG4105BZU Histidine kinase TepRe1_1569 ENOG4105CK6 Two component transcriptional regulator (Winged helix family TepRe1_1573 ENOG4105EAM Na Pi-cotransporter TepRe1_1574 ENOG4105EAM Na Pi-cotransporter TepRe1_1577 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator TepRe1_1578 ENOG4105C7J ABC transporter, permease TepRe1_1580 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) TepRe1_1582 ENOG4105CTX dehydratase TepRe1_1583 ENOG4107QZW Altronate oxidoreductase TepRe1_1584 ENOG4105DH8 myo-inositol catabolism TepRe1_1586 ENOG4105CG6 trap dicarboxylate transporter dctm subunit TepRe1_1588 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit TepRe1_1592 ENOG4105MWK D-amino acid dehydrogenase, small subunit TepRe1_1593 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein TepRe1_1598 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) TepRe1_1601 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) TepRe1_1607 ENOG4105DEF Extracellular solute-binding protein, family 5 TepRe1_1609 ENOG4108VMM UPF0756 membrane protein TepRe1_1610 ENOG4105E4C Lytic transglycosylase catalytic TepRe1_1611 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) TepRe1_1614 ENOG4105EMN RNA polymerase sigma factor TepRe1_1615 ENOG4108IV0 ABC, transporter TepRe1_1616 ENOG4105C0Z ABC transporter TepRe1_1617 ENOG4105CF8 branched-chain amino acid ABC transporter, permease TepRe1_1618 ENOG4105C32 Amino acid ABC transporter (Permease) TepRe1_1619 ENOG4105CP9 extracellular ligand-binding receptor TepRe1_1620 ENOG4105DUN Mediates zinc uptake. May also transport other divalent cations (By similarity) TepRe1_1621 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) TepRe1_1622 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) TepRe1_1624 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase TepRe1_1625 ENOG4105DK0 Indole-3-glycerol phosphate synthase TepRe1_1627 ENOG4105DDQ anthranilate synthase TepRe1_1628 ENOG4105CRQ synthase (Component I) TepRe1_1631 ENOG4105CS2 ec 3.2.1.21 TepRe1_1632 ENOG4105CAH Chromate TepRe1_1633 ENOG4105CAH Chromate TepRe1_1634 ENOG4105E2R ROK family TepRe1_1635 ENOG4105C4X radical SAM domain protein TepRe1_1637 ENOG4105CK1 PTS System TepRe1_1639 ENOG4105VCP PTS System TepRe1_1642 ENOG4105CK1 PTS System TepRe1_1644 ENOG4105VCP PTS System TepRe1_1645 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family TepRe1_1646 ENOG4105C8Q Methyl-accepting chemotaxis TepRe1_1647 ENOG4105F0V Cell wall hydrolase TepRe1_1648 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) TepRe1_1649 ENOG41076HS cation diffusion facilitator family transporter TepRe1_1651 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) TepRe1_1652 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) TepRe1_1655 ENOG4105C0H protease TepRe1_1656 ENOG4105CN1 protease TepRe1_1657 ENOG4105E4C Lytic transglycosylase catalytic TepRe1_1658 ENOG4105CRP Part of the ABC transporter FtsEX involved in TepRe1_1659 ENOG4105CAK Cell division ATP-binding protein ftsE TepRe1_1660 ENOG4105C8J )-transporter TepRe1_1661 ENOG4105CKB glycosidase TepRe1_1669 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) TepRe1_1670 ENOG4108HHA Transketolase TepRe1_1674 ENOG4105CPK Glycosyl transferase (Group 1 TepRe1_1677 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) TepRe1_1680 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase TepRe1_1681 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) TepRe1_1682 ENOG4105D2N Aldolase TepRe1_1684 ENOG4105S7A ErfK ybiS ycfS ynhG family protein TepRe1_1685 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) TepRe1_1686 ENOG4105C8M UPF0272 protein TepRe1_1687 ENOG4105DTC 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase TepRe1_1689 ENOG4105C7H Helicase, RecD TraA family TepRe1_1691 ENOG4105BZU Histidine kinase TepRe1_1693 ENOG4105C87 Aminotransferase class I and II TepRe1_1694 ENOG4108IQ3 PTS system TepRe1_1695 ENOG4105F3R pts system mannose fructose sorbose family iid TepRe1_1696 ENOG4105C5R Aminotransferase TepRe1_1698 ENOG4108IQ3 PTS system TepRe1_1699 ENOG4108EQA pts system TepRe1_1700 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family TepRe1_1703 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP TepRe1_1706 ENOG4107NFR Fructose-1,6-bisphosphatase TepRe1_1717 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) TepRe1_1718 ENOG4107RBB ABC transporter, permease TepRe1_1719 ENOG4105C19 ABC transporter TepRe1_1722 ENOG4105DVE abc transporter atp-binding protein TepRe1_1723 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family TepRe1_1724 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate TepRe1_1728 ENOG4105ETZ PTS System TepRe1_1731 ENOG4106KNT transcriptional regulator TepRe1_1732 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) TepRe1_1733 ENOG4105W8H transhydrogenase (subunit alpha TepRe1_1734 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) TepRe1_1736 ENOG4108JUB Transcriptional regulator TepRe1_1737 ENOG4105CI1 PTS System TepRe1_1739 ENOG4105CI1 PTS System TepRe1_1740 ENOG4108WYP Transcriptional regulator TepRe1_1741 ENOG4105DH8 myo-inositol catabolism TepRe1_1743 ENOG4105CPQ Dehydrogenase TepRe1_1745 ENOG4108IV0 ABC, transporter TepRe1_1746 ENOG4105C0Z ABC transporter TepRe1_1747 ENOG4105CF8 branched-chain amino acid ABC transporter, permease TepRe1_1748 ENOG4105C32 Amino acid ABC transporter (Permease) TepRe1_1749 ENOG4105CP9 extracellular ligand-binding receptor TepRe1_1751 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) TepRe1_1753 ENOG4105CMG Carbohydrate kinase TepRe1_1754 ENOG4108JQ1 Dehydrogenase TepRe1_1755 ENOG4105DEI Mannitol dehydrogenase TepRe1_1758 ENOG4105CJR Integral membrane protein (MviN TepRe1_1764 ENOG4108KMV Glycosyl transferase (Group 1 TepRe1_1770 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase TepRe1_1771 ENOG4105KJV Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) TepRe1_1774 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) TepRe1_1776 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) TepRe1_1777 ENOG4105D3Q Sugar transferase TepRe1_1786 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit TepRe1_1787 ENOG4108Z5K methylglyoxal synthase TepRe1_1789 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) TepRe1_1790 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) TepRe1_1791 ENOG4105ENT Efflux transporter rnd family, mfp subunit TepRe1_1792 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) TepRe1_1795 ENOG4107BJW polysaccharide deacetylase TepRe1_1801 ENOG4108RVA ribokinase TepRe1_1802 ENOG4105C2X Arabinose 5-phosphate isomerase TepRe1_1803 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) TepRe1_1804 ENOG4105C6K Malic enzyme TepRe1_1806 ENOG4105ERH Fumarylacetoacetate hydrolase TepRe1_1807 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) TepRe1_1808 ENOG4105DG4 malate L-lactate dehydrogenase TepRe1_1809 ENOG4108IV0 ABC, transporter TepRe1_1810 ENOG4105C0Z ABC transporter TepRe1_1811 ENOG4105CF8 branched-chain amino acid ABC transporter, permease TepRe1_1812 ENOG4105C32 Amino acid ABC transporter (Permease) TepRe1_1814 ENOG4105ETE Transcriptional regulator (LacI family TepRe1_1816 ENOG4105CK6 Two component transcriptional regulator (Winged helix family TepRe1_1819 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) TepRe1_1821 ENOG4108IYU L-aspartate oxidase TepRe1_1824 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) TepRe1_1825 ENOG4105E39 Enoyl-CoA hydratase TepRe1_1826 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) TepRe1_1827 ENOG4108Z7G MaoC domain protein dehydratase TepRe1_1828 ENOG4107Y0V Not clear, may be involved in an isomerization step TepRe1_1829 ENOG4105CG6 trap dicarboxylate transporter dctm subunit TepRe1_1830 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter TepRe1_1831 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit TepRe1_1832 ENOG4105E2X shikimate dehydrogenase TepRe1_1835 ENOG4108RTU Aldolase TepRe1_1836 ENOG410688J Ferredoxin TepRe1_1837 ENOG4108HWV )-transporter TepRe1_1838 ENOG4105C2J ABC transporter TepRe1_1839 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator TepRe1_1840 ENOG4105DFW ABC transporter TepRe1_1841 ENOG4108VAC response regulator TepRe1_1842 ENOG4108HRK Histidine kinase TepRe1_1846 ENOG4105C8Q Methyl-accepting chemotaxis TepRe1_1848 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) TepRe1_1849 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) TepRe1_1850 ENOG4108R6K riboflavin synthase, subunit alpha TepRe1_1851 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) TepRe1_1852 ENOG4105VI0 Pts system, glucitol sorbitol-specific TepRe1_1854 ENOG4105DZY Pts system, glucitol sorbitol-specific TepRe1_1855 ENOG410787A Pts system, glucitol sorbitol-specific TepRe1_1857 ENOG4107QN1 sodium solute TepRe1_1861 ENOG4107RCH Diaminopropionate ammonia-lyase TepRe1_1862 ENOG4108JUB Transcriptional regulator TepRe1_1863 ENOG4105CK1 PTS System TepRe1_1865 ENOG4105VCP PTS System TepRe1_1867 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family TepRe1_1875 ENOG4105DFD Na H antiporter TepRe1_1876 ENOG4105C0F tryptophanase EC 4.1.99.1 TepRe1_1880 ENOG4105WEF catalase TepRe1_1881 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit TepRe1_1883 ENOG4105DZB Electron transport complex TepRe1_1884 ENOG41080WF Electron transport complex, RnfABCDGE type, G subunit TepRe1_1885 ENOG4105D6A Electron transport complex TepRe1_1886 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) TepRe1_1887 ENOG4105TMB Formate nitrite transporter TepRe1_1888 ENOG4107QHI -hydrogenase TepRe1_1889 ENOG4107QIZ NADH dehydrogenase TepRe1_1891 ENOG4105BZU Histidine kinase TepRe1_1892 ENOG410902H NADH dehydrogenase (Ubiquinone), 24 kDa subunit TepRe1_1896 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase TepRe1_1897 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) TepRe1_1900 ENOG4108JQ7 (ABC) transporter TepRe1_1901 ENOG4105C3U ABC transporter TepRe1_1902 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component TepRe1_1903 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component TepRe1_1904 ENOG4105DEF Extracellular solute-binding protein, family 5 TepRe1_1905 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) TepRe1_1906 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) TepRe1_1907 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) TepRe1_1911 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family TepRe1_1912 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate TepRe1_1914 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase TepRe1_1921 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) TepRe1_1923 ENOG4105C28 cystathionine TepRe1_1926 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) TepRe1_1927 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) TepRe1_1928 ENOG4105CUT histidyl-tRNA synthetase TepRe1_1932 ENOG4107R8N Glycosyl transferase, family 2 TepRe1_1935 ENOG4105CM2 brancheD-chain amino acid aminotransferase TepRe1_1936 ENOG4105C7K acetolactate synthase TepRe1_1937 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) TepRe1_1938 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_1939 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_1940 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) TepRe1_1941 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase TepRe1_1943 ENOG4105C7K acetolactate synthase TepRe1_1948 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) TepRe1_1949 ENOG4105CH2 amidohydrolase TepRe1_1950 ENOG4107XCH Cyclase family TepRe1_1951 ENOG4105C01 Dihydroxy-acid dehydratase TepRe1_1952 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase TepRe1_1953 ENOG4105JXH GntR family transcriptional regulator TepRe1_1954 ENOG4108IUS Transketolase TepRe1_1955 ENOG4108HHA Transketolase TepRe1_1959 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit TepRe1_1964 ENOG4105C2F Histidine kinase TepRe1_1965 ENOG4105CDA abc transporter atp-binding protein TepRe1_1966 ENOG4105E5Q amino acid AbC transporter TepRe1_1967 ENOG4105CT1 (ABC) transporter TepRe1_1968 ENOG4105EAY pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for TepRe1_1970 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation TepRe1_1971 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination TepRe1_1972 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) TepRe1_1974 ENOG4105CP7 Triose-phosphate isomerase TepRe1_1975 ENOG4105BZA Phosphoglycerate kinase TepRe1_1978 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) TepRe1_1982 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) TepRe1_1984 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) TepRe1_1985 ENOG4108Z0R Transferase TepRe1_1988 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) TepRe1_1989 ENOG4105EPR degv family TepRe1_1991 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) TepRe1_1993 ENOG4105KG3 cytidine deaminase TepRe1_1994 ENOG4105FDP GntR family transcriptional regulator TepRe1_1997 ENOG4105UIB (ABC) transporter TepRe1_1998 ENOG4108JQ9 ABC transporter TepRe1_1999 ENOG4105DIH basic membrane TepRe1_2001 ENOG4105DGA Diaminopimelate dehydrogenase TepRe1_2004 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism TepRe1_2006 ENOG4105DY9 regulatoR TepRe1_2010 ENOG4108UIC UPF0340 protein TepRe1_2011 ENOG4105C0D helicase TepRe1_2012 ENOG4107XWB Zinc finger, swim domain protein TepRe1_2013 ENOG4106N3A copper homeostasis protein cutc TepRe1_2014 ENOG4108SU4 UPF0309 protein TepRe1_2017 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC TepRe1_2019 ENOG4106ETB IIa component TepRe1_2020 ENOG4105QUH Domain of unknown function (DUF2088) TepRe1_2023 ENOG4105C87 Aminotransferase class I and II TepRe1_2024 ENOG4108Z0Z intracellular protease Pfpi family TepRe1_2027 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) TepRe1_2028 ENOG4108626 Racemase TepRe1_2029 ENOG4106PKC pyridoxal phosphate binding TepRe1_2030 ENOG41080QX K07048 phosphotriesterase-related protein TepRe1_2031 ENOG4106M0N transport system permease protein TepRe1_2032 ENOG4105MUZ Protein of unknown function DUF2620 TepRe1_2034 ENOG4108M21 TepRe1_2035 ENOG4105J7I hydrolase TepRe1_2037 ENOG4108IGT Dipeptidase TepRe1_2038 ENOG4108UT2 hemolysin iii TepRe1_2041 ENOG4105CIH Imidazole acetol-phosphate transaminase TepRe1_2042 ENOG4105DFD Na H antiporter TepRe1_2043 ENOG41062D9 Histidine kinase TepRe1_2044 ENOG4105XJC Two component transcriptional regulator (Winged helix family TepRe1_2048 ENOG4105KTW ethanolamine utilization protein TepRe1_2049 ENOG4105M3W utilization protein TepRe1_2051 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) TepRe1_2053 ENOG4108FN7 Aldo keto reductase TepRe1_2054 ENOG4105CNN ABC, transporter TepRe1_2055 ENOG4105C2J ABC transporter TepRe1_2056 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator TepRe1_2059 ENOG4105CJ3 phosphate transporter TepRe1_2060 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) TepRe1_2064 ENOG41067VP Protein of unknown function (DUF1049) TepRe1_2065 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) TepRe1_2066 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj TepRe1_2067 ENOG4105CGA flagellar basal-body rod protein FlgG TepRe1_2069 ENOG4105DFF Rod shape-determining protein mreb TepRe1_2070 ENOG4105MT0 Sporulation transcriptional regulator spoiiid TepRe1_2071 ENOG4108K5P (LipO)protein TepRe1_2073 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) TepRe1_2076 ENOG4105M56 Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) TepRe1_2078 ENOG4108JIQ Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) TepRe1_2079 ENOG4105KXQ Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) TepRe1_2081 ENOG4105QD4 Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) TepRe1_2087 ENOG4105WJF TepRe1_2088 ENOG4108JCD RNA Polymerase TepRe1_2089 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase TepRe1_2090 ENOG4105ESV Glycosyl transferase, family 4 TepRe1_2092 ENOG4108HHA Transketolase TepRe1_2095 ENOG4105XN3 extracellular solute-binding protein family 1 TepRe1_2096 ENOG4107EJG GntR family transcriptional regulator TepRe1_2102 ENOG4108UK2 deaminase TepRe1_2105 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) TepRe1_2107 ENOG4107YBY Hydrolase TepRe1_2109 ENOG4105CK5 oxidoreductase TepRe1_2110 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) TepRe1_2111 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) TepRe1_2112 ENOG4108YZG isomerase TepRe1_2114 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) TepRe1_2116 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) TepRe1_2117 ENOG4105CBJ Metal-dependent enzyme TepRe1_2118 ENOG41082DI 50s ribosomal protein l31 TepRe1_2122 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) TepRe1_2123 ENOG4105CPI Metal Dependent Phosphohydrolase TepRe1_2124 ENOG4105NBF ammecr1 domain protein TepRe1_2130 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) TepRe1_2131 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) TepRe1_2135 ENOG4108UGV hypoxanthine phosphoribosyltransferase TepRe1_2138 ENOG4105C8Q Methyl-accepting chemotaxis TepRe1_2140 ENOG4105C6Z Gluconate TepRe1_2141 ENOG4105BZW Glycerate kinase TepRe1_2142 ENOG4105CMG Carbohydrate kinase TepRe1_2143 ENOG4105C6Z Gluconate TepRe1_2144 ENOG4105D2N Aldolase TepRe1_2145 ENOG4108JQ1 Dehydrogenase TepRe1_2146 ENOG4106KNT transcriptional regulator TepRe1_2147 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) TepRe1_2148 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit TepRe1_2149 ENOG4105CHR reductase TepRe1_2150 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) TepRe1_2155 ENOG4106J7S Glycosyl transferase, family 2 TepRe1_2156 ENOG4107Y70 Heat shock protein TepRe1_2157 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) TepRe1_2158 ENOG4108VZM 50s ribosomal protein L10 TepRe1_2160 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) TepRe1_2161 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) TepRe1_2162 ENOG410683Z Preprotein translocase SecE subunit TepRe1_2163 ENOG4105WDJ 50S ribosomal protein L33 TepRe1_2166 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) TepRe1_2167 ENOG4105QIV RNA polymerase TepRe1_2168 ENOG4105M0M Tetracycline resistance protein TepRe1_2169 ENOG4105C2N RNA methyltransferase TrmH family group 3 TepRe1_2171 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) TepRe1_2172 ENOG4105C8N cysteinyl-tRNA synthetase TepRe1_2173 ENOG4105D7W serine acetyltransferase TepRe1_2174 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) TepRe1_2175 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) TepRe1_2176 ENOG4105CTP PilT protein domain protein TepRe1_2177 ENOG4108VJ1 Transcriptional regulator (CarD family TepRe1_2179 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) TepRe1_2180 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit TepRe1_2181 ENOG41066A3 ATP guanido phosphotransferase TepRe1_2182 ENOG4108Z0C Uvrb UvrC protein TepRe1_2185 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) TepRe1_2186 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) TepRe1_2188 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family TepRe1_2189 ENOG4105VZJ PTS System TepRe1_2190 ENOG4105CK1 PTS System TepRe1_2193 ENOG4105F8D glycoside hydrolase family 4 TepRe1_2194 ENOG4107104 thymidine kinase TepRe1_2199 ENOG4105D78 K07001 NTE family protein TepRe1_2200 ENOG4105DDK oxidoreductase, beta subunit TepRe1_2201 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) TepRe1_2202 ENOG4105WGB oxidoreductase, delta subunit TepRe1_2203 ENOG4105EJ5 oxidoreductase gamma subunit TepRe1_2210 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate TepRe1_2212 ENOG4105CMG Carbohydrate kinase TepRe1_2213 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) TepRe1_2218 ENOG4108YZG isomerase TepRe1_2219 ENOG4105N2W Transcriptional regulator TepRe1_2220 ENOG4108UTZ Dihydroxyacetone kinase TepRe1_2221 ENOG4105CMT Dihydroxyacetone kinase TepRe1_2222 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) TepRe1_2225 ENOG4105CVR type I restriction-modification system TepRe1_2226 ENOG4105F27 Major Facilitator TepRe1_2235 ENOG4108WS4 fmn reductase TepRe1_2239 ENOG4105CJ1 ABC, transporter TepRe1_2240 ENOG41082YX Transcriptional regulator, arsr family TepRe1_2243 ENOG4105BZU Histidine kinase TepRe1_2245 ENOG4105VCP PTS System TepRe1_2247 ENOG4107QSE Dipeptidase TepRe1_2249 ENOG4105CK1 PTS System TepRe1_2252 ENOG4105ETD TRANSCRIPTIONal TepRe1_2253 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase TepRe1_2254 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) TepRe1_2255 ENOG4105EEI dihydropteroate synthase TepRe1_2256 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase TepRe1_2258 ENOG4105CS2 ec 3.2.1.21 TepRe1_2259 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase TepRe1_2260 ENOG4105CK1 PTS System TepRe1_2265 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase TepRe1_2272 ENOG4105QUH Domain of unknown function (DUF2088) TepRe1_2273 ENOG4105CHY citrate lyase, alpha TepRe1_2275 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) TepRe1_2276 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_2277 ENOG4107QM5 aconitate hydratase TepRe1_2280 ENOG4105C7F AcnD-accessory protein PrpF TepRe1_2282 ENOG4108KB2 LysR family Transcriptional regulator TepRe1_2284 ENOG4105DUA (citrate (pro-3S)-lyase ligase TepRe1_2290 ENOG4108UXE Protein tyrosine phosphatase TepRe1_2293 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_2294 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) TepRe1_2295 ENOG4105C6Z Gluconate TepRe1_2334 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) TepRe1_2335 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) TepRe1_2336 ENOG4105C6E dna polymerase iii TepRe1_2337 ENOG4108Z6B deaminase TepRe1_2338 ENOG4108Z7F N-acetyltransferase TepRe1_2339 ENOG4108ZJ4 polysaccharide deacetylase TepRe1_2340 ENOG4105W7A Protein of unknown function (DUF503) TepRe1_2341 ENOG4105E5Q amino acid AbC transporter TepRe1_2343 ENOG4105E5Q amino acid AbC transporter TepRe1_2344 ENOG4105CIF Ornithine Cyclodeaminase TepRe1_2345 ENOG4106TNF Periplasmic binding protein TepRe1_2347 ENOG4105C8J )-transporter TepRe1_2348 ENOG4105C0F tryptophanase EC 4.1.99.1 TepRe1_2349 ENOG4108JUB Transcriptional regulator TepRe1_2354 ENOG4105C6F GntR Family Transcriptional Regulator TepRe1_2356 ENOG4105BZJ Electron transfer flavoprotein TepRe1_2357 ENOG4105C10 Electron transfer flavoprotein TepRe1_2358 ENOG4105CQB FAD linked oxidase domain protein TepRe1_2362 ENOG4105JVQ RNA Polymerase TepRe1_2364 ENOG4108HQS Glycine betaine TepRe1_2367 ENOG4108ZJ4 polysaccharide deacetylase TepRe1_2368 ENOG4107QHQ amino acid TepRe1_2369 ENOG4105C87 Aminotransferase class I and II TepRe1_2371 ENOG4107VRI Transcriptional regulator TepRe1_2377 ENOG4105NA0 Transcriptional regulator TepRe1_2400 ENOG4105DNE Transposase TepRe1_2402 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) TepRe1_2403 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase TepRe1_2404 ENOG4105XSJ toxin secretion phage lysis holin TepRe1_2422 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) TepRe1_2424 ENOG4105CAR Terminase, large subunit TepRe1_2432 ENOG4105VXN addiction module toxin, RelE StbE family TepRe1_2439 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) TepRe1_2443 ENOG4105C2M dna polymerase I TepRe1_2454 ENOG4105ZU5 s-layer protein TepRe1_2456 ENOG4108TV1 Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity) TepRe1_2457 ENOG4108NVR Methyl-accepting chemotaxis TepRe1_2458 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) TepRe1_2459 ENOG4107WCI zn-dependent hydrolase of the beta-lactamase fold-like protein TepRe1_2460 ENOG4105C75 arginyL-tRNA synthetase TepRe1_2462 ENOG4107XPQ Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) TepRe1_2463 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) TepRe1_2464 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) TepRe1_2465 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) TepRe1_2467 ENOG4105CD3 dihydroorotase TepRe1_2468 ENOG4105CXT aspartate transcarbamylase TepRe1_2469 ENOG4105CQC Prephenate dehydratase TepRe1_2470 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase TepRe1_2472 ENOG4105D49 3-dehydroquinate synthase TepRe1_2473 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase TepRe1_2474 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase TepRe1_2476 ENOG4105E2X shikimate dehydrogenase TepRe1_2477 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) TepRe1_2478 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) TepRe1_2479 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) TepRe1_2480 ENOG4105F0V Cell wall hydrolase TepRe1_2481 ENOG4105XEW small acid-soluble spore protein TepRe1_2482 ENOG4105CXN decarboxylase TepRe1_2483 ENOG4108ZXQ stage ii sporulation protein r TepRe1_2486 ENOG4105VUC UPF0237 protein TepRe1_2492 ENOG4105CAH Chromate TepRe1_2493 ENOG4105CAH Chromate TepRe1_2495 ENOG4105CSV Glutaminase TepRe1_2499 ENOG4107QJQ Mate efflux family protein TepRe1_2500 ENOG4108MCI Transcriptional regulator, ARAC family TepRe1_2503 ENOG4105C9U ATP-dependent DNA helicase RecQ TepRe1_2504 ENOG4107QHI -hydrogenase TepRe1_2505 ENOG4107QIZ NADH dehydrogenase TepRe1_2506 ENOG410902H NADH dehydrogenase (Ubiquinone), 24 kDa subunit TepRe1_2513 ENOG4105CIG ABC transporter TepRe1_2516 ENOG4107R8N Glycosyl transferase, family 2 TepRe1_2520 ENOG4105C01 Dihydroxy-acid dehydratase TepRe1_2522 ENOG4106A3R peptidase TepRe1_2525 ENOG4107YTP response regulator receiver protein TepRe1_2527 ENOG4105WH1 Two component transcriptional regulator luxr family TepRe1_2528 ENOG4107R88 Chemotaxis protein (CheV) TepRe1_2531 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family TepRe1_2532 ENOG4105DRR Transcriptional regulator, GntR family TepRe1_2533 ENOG4105C8Q Methyl-accepting chemotaxis TepRe1_2534 ENOG4105BZU Histidine kinase TepRe1_2535 ENOG4105CPI Metal Dependent Phosphohydrolase TepRe1_2536 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family TepRe1_2537 ENOG4108EQA pts system TepRe1_2538 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB TepRe1_2539 ENOG4105ETZ PTS System TepRe1_2540 ENOG4105F3R pts system mannose fructose sorbose family iid TepRe1_2541 ENOG4105CPQ Dehydrogenase TepRe1_2544 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase TepRe1_2545 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) TepRe1_2546 ENOG4105C8Q Methyl-accepting chemotaxis TepRe1_2548 ENOG4105CEM UPF0597 protein TepRe1_2549 ENOG4108JUB Transcriptional regulator TepRe1_2551 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) TepRe1_2552 ENOG4105EPR degv family TepRe1_2555 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) TepRe1_2558 ENOG4107S52 alpha-2-macroglobulin domain protein TepRe1_2561 ENOG4107XJU UPF0178 protein TepRe1_2564 ENOG4105DIN metallophosphoesterase TepRe1_2565 ENOG4105CGK Exodeoxyribonuclease III TepRe1_2568 ENOG4105VFE sira family TepRe1_2569 ENOG41066VF YeeE YedE family protein TepRe1_2574 ENOG4105DM4 PTS System TepRe1_2575 ENOG4105DM4 PTS System TepRe1_2576 ENOG4105DE4 1-phosphofructokinase TepRe1_2577 ENOG4105E98 transcriptional regulator DeoR family TepRe1_2578 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) TepRe1_2581 ENOG4105IJJ transcriptional regulator, crp fnr family TepRe1_2588 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) TepRe1_2596 ENOG4105C3R Methionine synthase TepRe1_2598 ENOG4105E5Q amino acid AbC transporter TepRe1_2599 ENOG4106TNF Periplasmic binding protein TepRe1_2600 ENOG4105C0H protease TepRe1_2605 ENOG4105BZU Histidine kinase TepRe1_2606 ENOG4105CK6 Two component transcriptional regulator (Winged helix family TepRe1_2609 ENOG41061JJ Peptidase family M23 TepRe1_2611 ENOG4105DZ0 fad dependent oxidoreductase TepRe1_2613 ENOG4105CDU Replicative dna helicase TepRe1_2614 ENOG4105K9Q Binds to the 23S rRNA (By similarity) TepRe1_2615 ENOG4105BZR domain protein TepRe1_2616 ENOG4108XMW Membrane TepRe1_2617 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) TepRe1_2618 ENOG4108UUM single-stranded DNA-binding protein TepRe1_2619 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) TepRe1_2620 ENOG4105VDK protein, conserved in bacteria TepRe1_2621 ENOG4105D8X mechanosensitive ion channel TepRe1_2624 ENOG4108K88 Membrane TepRe1_2625 ENOG4108ZDA Sporulation protein YyaC TepRe1_2627 ENOG4108K5P (LipO)protein TepRe1_2630 ENOG41090HT Inherit from COG: transposase TepRe1_2631 ENOG4105FA0 parb-like partition protein TepRe1_2632 ENOG4107QJE Chromosome Partitioning Protein TepRe1_2634 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) TepRe1_2635 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) TepRe1_2636 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) TepRe1_2637 ENOG4108Z7S Single-stranded nucleic acid binding R3H domain-containing protein TepRe1_2638 ENOG4107R4E Membrane TepRe1_2639 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) TepRe1_2640 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) TepRe1_2641 ENOG4105VG0 50S ribosomal protein l34