locus-tag	class	description
LCC91_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCC91_00025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LCC91_00030	COG0321	lipoyl(octanoyl) transferase activity
LCC91_00035	COG2921	Belongs to the UPF0250 family
LCC91_00045	COG0356	it plays a direct role in the translocation of protons across the membrane
LCC91_00055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCC91_00060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCC91_00065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCC91_00070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCC91_00075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCC91_00085	COG0429	hydrolase of the alpha beta-hydrolase fold
LCC91_00095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LCC91_00100	COG3245	cytochrome
LCC91_00135	COG1337	RAMP superfamily
LCC91_00155	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCC91_00160	COG1518	maintenance of DNA repeat elements
LCC91_00165	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCC91_00275	COG0798	PFAM Bile acid sodium symporter
LCC91_00305	COG0625	glutathione transferase activity
LCC91_00320	COG4783	chaperone-mediated protein folding
LCC91_00325	COG0315	cyclic pyranopterin monophosphate synthase activity
LCC91_00330	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCC91_00350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCC91_00355	COG0792	nuclease activity
LCC91_00360	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LCC91_00370	COG2084	Dehydrogenase
LCC91_00385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LCC91_00390	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LCC91_00390	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LCC91_00390	COG0506	proline dehydrogenase activity
LCC91_00400	COG2423	ornithine cyclodeaminase activity
LCC91_00405	COG1522	sequence-specific DNA binding
LCC91_00415	COG0251	oxidation-reduction process
LCC91_00420	COG2423	ornithine cyclodeaminase activity
LCC91_00425	COG4251	negative regulation of phosphorylation
LCC91_00430	COG0277	FAD linked oxidase domain protein
LCC91_00435	COG0071	Belongs to the small heat shock protein (HSP20) family
LCC91_00440	COG0583	DNA-binding transcription factor activity
LCC91_00450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCC91_00455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCC91_00460	COG1522	sequence-specific DNA binding
LCC91_00485	COG0803	Belongs to the bacterial solute-binding protein 9 family
LCC91_00490	COG0709	Synthesizes selenophosphate from selenide and ATP
LCC91_00495	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LCC91_00505	COG0730	response to heat
LCC91_00525	COG0175	sulfate reduction
LCC91_00540	COG0584	glycerophosphoryl diester phosphodiesterase
LCC91_00545	COG3842	ATPase activity
LCC91_00550	COG0395	ABC-type sugar transport system, permease component
LCC91_00555	COG1175	transmembrane transport
LCC91_00560	COG1653	transport
LCC91_00585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LCC91_00585	COG2813	Specifically methylates the guanine in position
LCC91_00590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LCC91_00595	COG0724	RNA recognition motif
LCC91_00605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LCC91_00620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCC91_00625	COG0835	chemotaxis
LCC91_00630	COG0840	transmembrane signaling receptor activity
LCC91_00635	COG0840	transmembrane signaling receptor activity
LCC91_00650	COG2814	Major facilitator Superfamily
LCC91_00660	COG0189	ligase activity
LCC91_00675	COG3437	response regulator, receiver
LCC91_00680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCC91_00680	COG2205	protein histidine kinase activity
LCC91_00685	COG2814	Major facilitator Superfamily
LCC91_00690	COG0284	orotidine-5'-phosphate decarboxylase activity
LCC91_00705	COG0631	protein serine/threonine phosphatase activity
LCC91_00710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LCC91_00715	COG0045	succinate-CoA ligase (ADP-forming) activity
LCC91_00720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LCC91_00740	COG0318	PFAM AMP-dependent synthetase and ligase
LCC91_00755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LCC91_00760	COG0752	glycyl-tRNA synthetase alpha subunit
LCC91_00765	COG0751	glycine-tRNA ligase activity
LCC91_00770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LCC91_00790	COG0789	Transcriptional regulator
LCC91_00795	COG1960	acyl-CoA dehydrogenase activity
LCC91_00800	COG0288	reversible hydration of carbon dioxide
LCC91_00805	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LCC91_00810	COG0183	Belongs to the thiolase family
LCC91_00815	COG1960	acyl-CoA dehydrogenase activity
LCC91_00820	COG2161	toxin-antitoxin pair type II binding
LCC91_00825	COG2026	Addiction module toxin, RelE StbE family
LCC91_00830	COG0569	domain protein
LCC91_00870	COG3665	Urea carboxylase-associated protein
LCC91_00875	COG0439	Biotin carboxylase
LCC91_00890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LCC91_00895	COG1024	Enoyl-CoA hydratase
LCC91_00905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCC91_00925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LCC91_00930	COG3383	formate dehydrogenase (NAD+) activity
LCC91_00950	COG0589	response to stress
LCC91_00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCC91_00970	COG2391	methyltransferase activity
LCC91_00980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LCC91_00985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LCC91_00990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCC91_00995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCC91_01005	COG0494	nUDIX hydrolase
LCC91_01010	COG0442	prolyl-tRNA aminoacylation
LCC91_01025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LCC91_01030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LCC91_01040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCC91_01045	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LCC91_01070	COG2226	methyltransferase
LCC91_01085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LCC91_01100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LCC91_01120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LCC91_01125	COG1360	Flagellar Motor Protein
LCC91_01130	COG0745	RESPONSE REGULATOR receiver
LCC91_01135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LCC91_01180	COG1815	bacterial-type flagellum-dependent cell motility
LCC91_01185	COG1558	bacterial-type flagellum-dependent cell motility
LCC91_01190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LCC91_01205	COG4786	Flagellar basal body rod
LCC91_01215	COG1706	bacterial-type flagellum-dependent cell motility
LCC91_01220	COG1705	Flagellar rod assembly protein muramidase FlgJ
LCC91_01220	COG3951	Flagellar rod assembly protein muramidase FlgJ
LCC91_01225	COG1256	bacterial-type flagellum assembly
LCC91_01245	COG1960	acyl-CoA dehydrogenase activity
LCC91_01250	COG1960	acyl-CoA dehydrogenase activity
LCC91_01260	COG0459	protein refolding
LCC91_01265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCC91_01285	COG1024	Enoyl-CoA hydratase
LCC91_01295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LCC91_01300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LCC91_01310	COG0012	GTP binding
LCC91_01315	COG3002	Belongs to the UPF0753 family
LCC91_01320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LCC91_01325	COG0583	DNA-binding transcription factor activity
LCC91_01330	COG1410	methionine synthase
LCC91_01330	COG0646	methionine synthase
LCC91_01355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCC91_01370	COG0004	ammonium transporteR
LCC91_01380	COG0768	penicillin binding
LCC91_01395	COG1077	Cell shape determining protein MreB Mrl
LCC91_01400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCC91_01405	COG0154	amidase activity
LCC91_01420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCC91_01430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCC91_01450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LCC91_01465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LCC91_01475	COG0346	lactoylglutathione lyase activity
LCC91_01480	COG0513	Belongs to the DEAD box helicase family
LCC91_01485	COG0488	(ABC) transporter
LCC91_01495	COG0745	RESPONSE REGULATOR receiver
LCC91_01505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCC91_01515	COG0138	bifunctional purine biosynthesis protein purh
LCC91_01525	COG0424	maF-like protein
LCC91_01535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LCC91_01535	COG0616	signal peptide processing
LCC91_01540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LCC91_01550	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LCC91_01555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCC91_01570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCC91_01590	COG0228	four-way junction DNA binding
LCC91_01595	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCC91_01600	COG0336	Belongs to the RNA methyltransferase TrmD family
LCC91_01605	COG0335	large ribosomal subunit rRNA binding
LCC91_01620	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCC91_01635	COG0612	Peptidase, M16
LCC91_01640	COG0612	Peptidase, M16
LCC91_01645	COG0742	ribosomal rna small subunit methyltransferase
LCC91_01650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCC91_01655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LCC91_01660	COG0193	aminoacyl-tRNA hydrolase activity
LCC91_01665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LCC91_01670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCC91_01680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCC91_01685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LCC91_01695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LCC91_01715	COG0497	DNA recombination
LCC91_01720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCC91_01725	COG1420	regulation of RNA biosynthetic process
LCC91_01745	COG1121	(ABC) transporter
LCC91_01750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCC91_01755	COG0402	S-adenosylhomocysteine deaminase activity
LCC91_01765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCC91_01770	COG0577	efflux transmembrane transporter activity
LCC91_01770	COG1136	(ABC) transporter
LCC91_01775	COG1136	(ABC) transporter
LCC91_01775	COG0577	efflux transmembrane transporter activity
LCC91_01825	COG1199	ATP-dependent helicase activity
LCC91_01830	COG3622	Belongs to the hyi family
LCC91_01845	COG3845	ABC transporter
LCC91_01850	COG4603	Belongs to the binding-protein-dependent transport system permease family
LCC91_01855	COG1079	Belongs to the binding-protein-dependent transport system permease family
LCC91_01870	COG0717	Belongs to the dCTP deaminase family
LCC91_01920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LCC91_01925	COG1476	TRANSCRIPTIONal
LCC91_01940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LCC91_01945	COG0277	FAD linked oxidase domain protein
LCC91_01955	COG1295	ribonuclease BN
LCC91_01960	COG0004	ammonium transporteR
LCC91_01985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LCC91_02000	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LCC91_02010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LCC91_02015	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LCC91_02020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCC91_02030	COG1968	undecaprenyl-diphosphatase activity
LCC91_02045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCC91_02050	COG1074	ATP-dependent DNA helicase activity
LCC91_02055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LCC91_02065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCC91_02070	COG1758	RNA polymerase activity
LCC91_02075	COG0194	GDP metabolic process
LCC91_02080	COG1561	YicC-like family, N-terminal region
LCC91_02095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LCC91_02100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCC91_02105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCC91_02110	COG0517	IMP dehydrogenase activity
LCC91_02110	COG0617	tRNA 3'-terminal CCA addition
LCC91_02110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCC91_02125	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LCC91_02140	COG0215	cysteine-tRNA ligase activity
LCC91_02150	COG0825	malonyl-CoA metabolic process
LCC91_02155	COG0037	tRNA processing
LCC91_02175	COG0252	asparaginase activity
LCC91_02180	COG0563	adenylate kinase activity
LCC91_02185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LCC91_02190	COG2835	tetraacyldisaccharide 4'-kinase activity
LCC91_02195	COG1663	tetraacyldisaccharide 4'-kinase activity
LCC91_02200	COG0848	biopolymer transport protein
LCC91_02205	COG0811	peptide transport
LCC91_02210	COG1570	exodeoxyribonuclease VII activity
LCC91_02215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LCC91_02235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LCC91_02240	COG0542	response to heat
LCC91_02250	COG2925	Exonuclease
LCC91_02260	COG0433	COG0433 Predicted ATPase
LCC91_02265	COG0217	transcriptional regulatory protein
LCC91_02270	COG0151	Belongs to the GarS family
LCC91_02275	COG0408	coproporphyrinogen oxidase activity
LCC91_02280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCC91_02285	COG0799	negative regulation of ribosome biogenesis
LCC91_02290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCC91_02295	COG0424	maF-like protein
LCC91_02305	COG1132	(ABC) transporter
LCC91_02310	COG0823	Involved in the tonB-independent uptake of proteins
LCC91_02325	COG2391	methyltransferase activity
LCC91_02330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LCC91_02345	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LCC91_02355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LCC91_02370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCC91_02375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LCC91_02385	COG0268	Binds directly to 16S ribosomal RNA
LCC91_02395	COG0513	Belongs to the DEAD box helicase family
LCC91_02400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LCC91_02405	COG1253	flavin adenine dinucleotide binding
LCC91_02415	COG1850	ribulose-bisphosphate carboxylase activity
LCC91_02445	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LCC91_02450	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LCC91_02465	COG1192	Involved in chromosome partitioning
LCC91_02485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LCC91_02510	COG0210	DNA helicase
LCC91_02515	COG3046	protein related to deoxyribodipyrimidine photolyase
LCC91_02520	COG0415	Belongs to the DNA photolyase family
LCC91_02530	COG0415	Belongs to the DNA photolyase family
LCC91_02565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCC91_02595	COG0697	spore germination
LCC91_02600	COG0583	DNA-binding transcription factor activity
LCC91_02605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCC91_02610	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LCC91_02615	COG3954	Phosphoribulokinase
LCC91_02620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LCC91_02625	COG0546	phosphoglycolate phosphatase activity
LCC91_02630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LCC91_02635	COG0126	phosphoglycerate kinase activity
LCC91_02640	COG0191	fructose-bisphosphate aldolase activity
LCC91_02645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCC91_02650	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LCC91_02660	COG0776	regulation of translation
LCC91_02670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LCC91_02675	COG0287	Prephenate dehydrogenase
LCC91_02685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LCC91_02700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LCC91_02725	COG2119	membrane
LCC91_02735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCC91_02745	COG1116	anion transmembrane transporter activity
LCC91_02760	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LCC91_02765	COG2414	aldehyde ferredoxin oxidoreductase
LCC91_02790	COG2974	May be involved in recombination
LCC91_02815	COG1177	transmembrane transport
LCC91_02820	COG1176	ABC-type spermidine putrescine transport system, permease component I
LCC91_02830	COG3842	ATPase activity
LCC91_02835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LCC91_02840	COG1960	acyl-CoA dehydrogenase activity
LCC91_02845	COG0583	DNA-binding transcription factor activity
LCC91_02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCC91_02865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LCC91_02870	COG0484	heat shock protein binding
LCC91_02875	COG0443	Heat shock 70 kDa protein
LCC91_02880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCC91_02885	COG0179	Fumarylacetoacetate (FAA) hydrolase
LCC91_02895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LCC91_02925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LCC91_02940	COG3852	Histidine kinase
LCC91_02965	COG3300	MHYT domain
LCC91_02965	COG5001	Diguanylate cyclase
LCC91_02995	COG0457	Tetratricopeptide repeat
LCC91_03000	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LCC91_03010	COG1215	transferase activity, transferring glycosyl groups
LCC91_03030	COG1215	transferase activity, transferring glycosyl groups
LCC91_03040	COG1840	ABC-type Fe3 transport system, periplasmic component
LCC91_03045	COG1752	Esterase of the alpha-beta hydrolase superfamily
LCC91_03055	COG0123	including yeast histone deacetylase and acetoin utilization protein
LCC91_03075	COG0003	Pfam Anion-transporting ATPase
LCC91_03085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCC91_03090	COG2111	Na H antiporter
LCC91_03090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LCC91_03095	COG2111	Na H antiporter
LCC91_03100	COG1006	Multisubunit Na H antiporter MnhC subunit
LCC91_03105	COG0651	ATP synthesis coupled electron transport
LCC91_03115	COG2212	antiporter activity
LCC91_03120	COG1320	monovalent cation:proton antiporter activity
LCC91_03125	COG2111	Na H antiporter
LCC91_03125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LCC91_03130	COG1006	Multisubunit Na H antiporter MnhC subunit
LCC91_03135	COG0651	ATP synthesis coupled electron transport
LCC91_03145	COG2212	antiporter activity
LCC91_03150	COG1320	monovalent cation:proton antiporter activity
LCC91_03155	COG1611	Belongs to the LOG family
LCC91_03160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCC91_03180	COG0322	excinuclease ABC activity
LCC91_03190	COG0697	spore germination
LCC91_03195	COG0473	3-isopropylmalate dehydrogenase activity
LCC91_03210	COG0250	Participates in transcription elongation, termination and antitermination
LCC91_03220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCC91_03245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LCC91_03270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCC91_03275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LCC91_03290	COG0367	asparagine synthase
LCC91_03295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCC91_03295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCC91_03305	COG3039	Transposase
LCC91_03320	COG0534	Mate efflux family protein
LCC91_03335	COG0367	asparagine synthase
LCC91_03375	COG0438	transferase activity, transferring glycosyl groups
LCC91_03390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCC91_03395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCC91_03430	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCC91_03450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LCC91_03460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCC91_03495	COG3128	pkhd-type hydroxylase
LCC91_03500	COG4774	siderophore transport
LCC91_03510	COG3634	alkyl hydroperoxide reductase activity
LCC91_03515	COG1629	transport
LCC91_03515	COG4771	TonB-dependent receptor
LCC91_03520	COG3720	iron ion transport
LCC91_03525	COG4558	Periplasmic binding protein
LCC91_03530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCC91_03535	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LCC91_03540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LCC91_03545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCC91_03580	COG0642	Histidine kinase
LCC91_03585	COG2194	sulfuric ester hydrolase activity
LCC91_03590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LCC91_03595	COG3161	chorismate lyase activity
LCC91_03620	COG5001	Diguanylate cyclase
LCC91_03620	COG3300	MHYT domain
LCC91_03625	COG2308	Evidence 4 Homologs of previously reported genes of
LCC91_03645	COG2358	TRAP transporter, solute receptor (TAXI family
LCC91_03660	COG0714	Associated with various cellular activities
LCC91_03665	COG0123	including yeast histone deacetylase and acetoin utilization protein
LCC91_03670	COG1024	Enoyl-CoA hydratase
LCC91_03675	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LCC91_03675	COG3264	Mechanosensitive ion channel
LCC91_03690	COG1960	acyl-CoA dehydrogenase activity
LCC91_03700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LCC91_03715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCC91_03725	COG1196	nuclear chromosome segregation
LCC91_03740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCC91_03745	COG2814	Major facilitator Superfamily
LCC91_03750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LCC91_03755	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCC91_03760	COG0802	atpase or kinase
LCC91_03765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LCC91_03785	COG1432	Conserved Protein
LCC91_03795	COG0328	RNA-DNA hybrid ribonuclease activity
LCC91_03800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCC91_03805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LCC91_03820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LCC91_03825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LCC91_03830	COG3737	Protein of unknown function (DUF498/DUF598)
LCC91_03835	COG0436	Aminotransferase
LCC91_03845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LCC91_03860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LCC91_03865	COG0314	molybdopterin synthase activity
LCC91_03870	COG0542	response to heat
LCC91_03880	COG0463	Glycosyl transferase, family 2
LCC91_03890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCC91_03900	COG2917	probably involved in intracellular septation
LCC91_03905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCC91_03910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LCC91_03930	COG2801	Transposase and inactivated derivatives
LCC91_03960	COG2072	flavoprotein involved in K transport
LCC91_03995	COG0318	PFAM AMP-dependent synthetase and ligase
LCC91_04015	COG0411	ABC transporter
LCC91_04030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCC91_04035	COG0360	Binds together with S18 to 16S ribosomal RNA
LCC91_04040	COG2965	DNA replication, synthesis of RNA primer
LCC91_04045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LCC91_04050	COG0359	binds to the 23S rRNA
LCC91_04060	COG0564	pseudouridine synthase activity
LCC91_04065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCC91_04075	COG0105	UTP biosynthetic process
LCC91_04080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LCC91_04100	COG0124	histidyl-tRNA synthetase
LCC91_04105	COG2976	Protein conserved in bacteria
LCC91_04110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LCC91_04115	COG1160	GTP binding
LCC91_04120	COG1923	regulation of RNA biosynthetic process
LCC91_04125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCC91_04130	COG0330	HflC and HflK could
LCC91_04135	COG0330	HflC and HflK could
LCC91_04140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LCC91_04145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LCC91_04160	COG0010	Belongs to the arginase family
LCC91_04165	COG1228	amidohydrolase
LCC91_04170	COG2986	histidine ammonia-lyase
LCC91_04175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LCC91_04180	COG3314	Sporulation integral membrane protein YlbJ
LCC91_04195	COG4181	ATPase activity
LCC91_04200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCC91_04215	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
LCC91_04220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCC91_04235	COG0557	exoribonuclease II activity
LCC91_04240	COG0762	integral membrane protein
LCC91_04245	COG0303	'Molybdopterin
LCC91_04250	COG0746	molybdenum cofactor guanylyltransferase activity
LCC91_04255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LCC91_04265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LCC91_04280	COG0347	Belongs to the P(II) protein family
LCC91_04295	COG0028	Belongs to the TPP enzyme family
LCC91_04300	COG0440	acetolactate synthase activity
LCC91_04305	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LCC91_04310	COG1183	phosphatidylcholine synthase activity
LCC91_04315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCC91_04325	COG1414	Transcriptional regulator
LCC91_04330	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LCC91_04335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LCC91_04340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCC91_04345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCC91_04405	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LCC91_04410	COG0560	Phosphoserine phosphatase
LCC91_04415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCC91_04420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCC91_04425	COG0596	Alpha beta hydrolase
LCC91_04445	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LCC91_04445	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LCC91_04465	COG1028	Short-chain dehydrogenase reductase Sdr
LCC91_04475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCC91_04510	COG2186	Transcriptional regulator
LCC91_04525	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LCC91_04530	COG0830	nickel cation binding
LCC91_04535	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LCC91_04540	COG0804	urea catabolic process
LCC91_04545	COG0832	Belongs to the urease beta subunit family
LCC91_04555	COG0831	urea catabolic process
LCC91_04560	COG2198	Histidine kinase
LCC91_04560	COG0784	Response regulator, receiver
LCC91_04560	COG2205	protein histidine kinase activity
LCC91_04595	COG0829	nickel cation binding
LCC91_04600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCC91_04605	COG1116	anion transmembrane transporter activity
LCC91_04625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LCC91_04675	COG2197	response regulator
LCC91_04700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LCC91_04705	COG1140	nitrate reductase beta subunit
LCC91_04710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LCC91_04715	COG2181	nitrate reductase activity
LCC91_04725	COG0069	glutamate synthase activity
LCC91_04745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LCC91_04750	COG0163	prenyltransferase activity
LCC91_04760	COG3154	lipid carrier protein
LCC91_04765	COG0826	peptidase U32
LCC91_04770	COG0826	peptidase U32
LCC91_04775	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LCC91_04780	COG1959	2 iron, 2 sulfur cluster binding
LCC91_04820	COG2022	thiamine diphosphate biosynthetic process
LCC91_04835	COG0352	thiamine-phosphate diphosphorylase activity
LCC91_04835	COG0351	phosphomethylpyrimidine kinase
LCC91_04840	COG0492	ferredoxin-NADP+ reductase activity
LCC91_04845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LCC91_04860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCC91_04860	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LCC91_04865	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LCC91_04875	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LCC91_04880	COG0579	oxidoreductase
LCC91_04890	COG0167	dihydroorotate dehydrogenase activity
LCC91_04895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCC91_04905	COG1534	Rna-binding protein
LCC91_04910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LCC91_04915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCC91_04925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCC91_04955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCC91_04960	COG0581	inorganic phosphate transmembrane transporter activity
LCC91_04965	COG0573	inorganic phosphate transmembrane transporter activity
LCC91_04970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LCC91_04995	COG0254	rRNA binding
LCC91_05000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LCC91_05015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCC91_05020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCC91_05025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCC91_05035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCC91_05045	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LCC91_05050	COG0024	Methionine aminopeptidase
LCC91_05075	COG0779	Required for maturation of 30S ribosomal subunits
LCC91_05080	COG0195	Participates in both transcription termination and antitermination
LCC91_05085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCC91_05090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCC91_05095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LCC91_05100	COG1217	gtp-binding protein TYPA
LCC91_05110	COG1024	Enoyl-CoA hydratase
LCC91_05115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LCC91_05120	COG2867	negative regulation of translational initiation
LCC91_05125	COG2914	Belongs to the UPF0125 (RnfH) family
LCC91_05145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LCC91_05145	COG0519	Catalyzes the synthesis of GMP from XMP
LCC91_05170	COG1619	proteins homologs of microcin C7 resistance protein MccF
LCC91_05175	COG0189	ligase activity
LCC91_05175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCC91_05180	COG0189	ligase activity
LCC91_05180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCC91_05185	COG1132	(ABC) transporter
LCC91_05205	COG4160	amino acid transport
LCC91_05210	COG4215	(ABC) transporter
LCC91_05235	COG0084	hydrolase, TatD family'
LCC91_05250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCC91_05260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCC91_05275	COG2153	protein acetylation
LCC91_05280	COG0826	peptidase U32
LCC91_05290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCC91_05290	COG0047	phosphoribosylformylglycinamidine synthase activity
LCC91_05320	COG0791	NLP P60 protein
LCC91_05325	COG2841	Protein conserved in bacteria
LCC91_05385	COG0582	viral genome integration into host DNA
LCC91_05395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LCC91_05400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCC91_05405	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCC91_05410	COG0567	Dehydrogenase, E1 component
LCC91_05425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCC91_05445	COG0633	Ferredoxin
LCC91_05450	COG0443	Heat shock 70 kDa protein
LCC91_05455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LCC91_05465	COG0822	iron-sulfur transferase activity
LCC91_05470	COG1104	cysteine desulfurase activity
LCC91_05475	COG1959	2 iron, 2 sulfur cluster binding
LCC91_05480	COG3851	Histidine kinase
LCC91_05485	COG2197	response regulator
LCC91_05490	COG0556	nucleotide-excision repair
LCC91_05505	COG2878	Part of a membrane complex involved in electron transport
LCC91_05515	COG4770	biotin carboxylase activity
LCC91_05520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LCC91_05530	COG1703	isobutyryl-CoA mutase activity
LCC91_05535	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LCC91_05535	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LCC91_05540	COG1802	Transcriptional regulator
LCC91_05550	COG1028	Short-chain dehydrogenase reductase Sdr
LCC91_05555	COG0183	Belongs to the thiolase family
LCC91_05560	COG3243	poly(R)-hydroxyalkanoic acid synthase
LCC91_05600	COG1196	nuclear chromosome segregation
LCC91_05605	COG0436	Aminotransferase
LCC91_05610	COG2171	N-acyltransferase activity
LCC91_05620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCC91_05640	COG2890	protein-(glutamine-N5) methyltransferase activity
LCC91_05645	COG0488	(ABC) transporter
LCC91_05650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCC91_05650	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LCC91_05660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCC91_05670	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCC91_05675	COG1024	Enoyl-CoA hydratase
LCC91_05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCC91_05710	COG4172	Belongs to the ABC transporter superfamily
LCC91_05715	COG4239	(ABC) transporter, permease
LCC91_05720	COG4174	ABC transporter (Permease)
LCC91_05740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCC91_05745	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCC91_05750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LCC91_05760	COG4566	intracellular signal transduction
LCC91_05765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LCC91_05775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCC91_05780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LCC91_05785	COG0505	Belongs to the CarA family
LCC91_05790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCC91_05795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCC91_05800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LCC91_05805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LCC91_05810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LCC91_05815	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LCC91_05830	COG0750	zinc metalloprotease
LCC91_05835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LCC91_05840	COG0575	Belongs to the CDS family
LCC91_05845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCC91_05850	COG0233	cytoplasmic translational termination
LCC91_05855	COG0528	UMP kinase activity
LCC91_05860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCC91_05865	COG0052	Belongs to the universal ribosomal protein uS2 family
LCC91_05870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LCC91_05870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LCC91_05875	COG1525	nuclease
LCC91_05880	COG1414	Transcriptional regulator
LCC91_05895	COG1012	belongs to the aldehyde dehydrogenase family
LCC91_05895	COG2030	dehydratase
LCC91_05900	COG0657	acetylesterase activity
LCC91_05920	COG1639	'signal transduction protein
LCC91_05925	COG2183	response to ionizing radiation
LCC91_05940	COG1960	acyl-CoA dehydrogenase activity
LCC91_05945	COG2130	NADP-dependent
LCC91_05955	COG1028	Short-chain dehydrogenase reductase Sdr
LCC91_05960	COG1960	acyl-CoA dehydrogenase activity
LCC91_05965	COG0183	Belongs to the thiolase family
LCC91_05970	COG1024	Enoyl-CoA hydratase
LCC91_05970	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCC91_05985	COG2176	DNA-directed DNA polymerase activity
LCC91_05985	COG5002	protein histidine kinase activity
LCC91_05990	COG0745	RESPONSE REGULATOR receiver
LCC91_05995	COG5002	protein histidine kinase activity
LCC91_06010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LCC91_06020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCC91_06035	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LCC91_06040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LCC91_06045	COG1492	cobalamin metabolic process
LCC91_06050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCC91_06055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LCC91_06080	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LCC91_06090	COG2875	Belongs to the precorrin methyltransferase family
LCC91_06100	COG2099	Precorrin-6x reductase
LCC91_06130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LCC91_06135	COG1120	ATPase activity
LCC91_06140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCC91_06145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCC91_06165	COG1797	cobyrinic acid a,c-diamide synthase activity
LCC91_06195	COG0730	response to heat
LCC91_06200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LCC91_06225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LCC91_06240	COG0583	DNA-binding transcription factor activity
LCC91_06245	COG0436	Aminotransferase
LCC91_06250	COG1643	Atp-dependent helicase
LCC91_06255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LCC91_06255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LCC91_06265	COG2850	peptidyl-arginine hydroxylation
LCC91_06275	COG0756	dUTP diphosphatase activity
LCC91_06280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LCC91_06280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LCC91_06290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LCC91_06295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LCC91_06300	COG0142	geranyltranstransferase activity
LCC91_06305	COG1722	exodeoxyribonuclease VII activity
LCC91_06350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LCC91_06370	COG0210	DNA helicase
LCC91_06385	COG0516	GMP reductase activity
LCC91_06395	COG0306	phosphate transporter
LCC91_06400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LCC91_06405	COG0501	Belongs to the peptidase M48B family
LCC91_06410	COG1162	GTPase activity
LCC91_06425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCC91_06445	COG1007	ATP synthesis coupled electron transport
LCC91_06460	COG0713	ATP synthesis coupled electron transport
LCC91_06470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCC91_06475	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LCC91_06480	COG1034	ATP synthesis coupled electron transport
LCC91_06490	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LCC91_06495	COG0649	NAD binding
LCC91_06500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCC91_06505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCC91_06510	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCC91_06525	COG0149	triose-phosphate isomerase activity
LCC91_06530	COG0604	alcohol dehydrogenase
LCC91_06535	COG1185	polyribonucleotide nucleotidyltransferase activity
LCC91_06540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LCC91_06545	COG0683	leucine binding
LCC91_06550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LCC91_06585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCC91_06615	COG0285	dihydrofolate synthase activity
LCC91_06620	COG1393	Belongs to the ArsC family
LCC91_06625	COG3123	guanosine phosphorylase activity
LCC91_06630	COG0137	argininosuccinate synthase activity
LCC91_06645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LCC91_06650	COG1666	GTP binding
LCC91_06660	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LCC91_06665	COG0667	Aldo Keto reductase
LCC91_06670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCC91_06690	COG0308	aminopeptidase N
LCC91_06695	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LCC91_06750	COG1872	DUF167
LCC91_06755	COG1309	transcriptional regulator
LCC91_06770	COG2026	Addiction module toxin, RelE StbE family
LCC91_06780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCC91_06785	COG0504	CTP synthase activity
LCC91_06790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LCC91_06800	COG0148	phosphopyruvate hydratase activity
LCC91_06805	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LCC91_06810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LCC91_06820	COG2833	Protein of unknown function (DUF455)
LCC91_06825	COG4974	Belongs to the 'phage' integrase family
LCC91_06830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCC91_06835	COG1388	LysM domain
LCC91_06835	COG0741	lytic transglycosylase activity
LCC91_06860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LCC91_06865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCC91_06870	COG0740	serine-type endopeptidase activity
LCC91_06875	COG0544	peptidyl-prolyl cis-trans isomerase activity
LCC91_06910	COG1562	ergosterol biosynthetic process
LCC91_06920	COG0625	glutathione transferase activity
LCC91_06925	COG1011	Hydrolase
LCC91_06930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LCC91_06935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCC91_06955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LCC91_06960	COG0509	glycine decarboxylation via glycine cleavage system
LCC91_06965	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LCC91_06965	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LCC91_06975	COG2860	membrane
LCC91_06980	COG3384	dioxygenase
LCC91_06985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCC91_06990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LCC91_07010	COG1230	cation diffusion facilitator family transporter
LCC91_07025	COG0701	Predicted permease
LCC91_07040	COG0312	modulator of DNA gyrase
LCC91_07045	COG3028	Belongs to the UPF0307 family
LCC91_07050	COG0521	Mo-molybdopterin cofactor biosynthetic process
LCC91_07055	COG1045	serine acetyltransferase
LCC91_07065	COG0483	inositol monophosphate 1-phosphatase activity
LCC91_07070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCC91_07075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LCC91_07110	COG0776	regulation of translation
LCC91_07115	COG0072	phenylalanine-tRNA ligase activity
LCC91_07115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCC91_07120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCC91_07125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCC91_07130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LCC91_07135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCC91_07140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCC91_07145	COG0778	Nitroreductase
LCC91_07150	COG2224	Isocitrate lyase
LCC91_07160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LCC91_07170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LCC91_07175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LCC91_07180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LCC91_07185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LCC91_07190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LCC91_07200	COG0588	phosphoglycerate mutase activity
LCC91_07205	COG0793	Belongs to the peptidase S41A family
LCC91_07210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCC91_07220	COG0302	gtp cyclohydrolase
LCC91_07230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCC91_07245	COG1487	ribonuclease activity
LCC91_07250	COG0494	nUDIX hydrolase
LCC91_07275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LCC91_07295	COG1677	Flagellar hook-basal body complex protein FliE
LCC91_07300	COG1766	The M ring may be actively involved in energy transduction
LCC91_07305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCC91_07310	COG1317	bacterial-type flagellum organization
LCC91_07340	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCC91_07350	COG1338	Plays a role in the flagellum-specific transport system
LCC91_07355	COG1987	bacterial-type flagellum assembly
LCC91_07380	COG0745	RESPONSE REGULATOR receiver
LCC91_07385	COG2198	Histidine kinase
LCC91_07385	COG0643	Histidine kinase
LCC91_07395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LCC91_07400	COG2201	protein-glutamate methylesterase activity
LCC91_07435	COG2050	protein possibly involved in aromatic compounds catabolism
LCC91_07440	COG1024	Enoyl-CoA hydratase
LCC91_07445	COG0183	Belongs to the thiolase family
LCC91_07450	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCC91_07450	COG1024	Enoyl-CoA hydratase
LCC91_07460	COG1960	acyl-CoA dehydrogenase activity
LCC91_07470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LCC91_07485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCC91_07490	COG0708	Exodeoxyribonuclease III
LCC91_07510	COG0174	glutamine synthetase
LCC91_07515	COG1546	Belongs to the CinA family
LCC91_07515	COG1058	Belongs to the CinA family
LCC91_07540	COG2959	enzyme of heme biosynthesis
LCC91_07550	COG0181	hydroxymethylbilane synthase activity
LCC91_07560	COG0165	Argininosuccinate lyase
LCC91_07565	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LCC91_07575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCC91_07705	COG5005	Phage virion morphogenesis
LCC91_07855	COG1061	Type III restriction enzyme res subunit
LCC91_07865	COG0756	dUTP diphosphatase activity
LCC91_07930	COG1178	ABC-type Fe3 transport system permease component
LCC91_07935	COG3842	ATPase activity
LCC91_07955	COG1999	signal sequence binding
LCC91_07990	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LCC91_07995	COG0237	dephospho-CoA kinase activity
LCC91_08000	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LCC91_08005	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LCC91_08015	COG0494	nUDIX hydrolase
LCC91_08025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LCC91_08030	COG0653	protein targeting
LCC91_08050	COG2133	pyrroloquinoline quinone binding
LCC91_08075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCC91_08100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LCC91_08125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCC91_08130	COG1280	lysine exporter protein (LysE YggA)
LCC91_08135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LCC91_08145	COG0492	ferredoxin-NADP+ reductase activity
LCC91_08150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LCC91_08155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LCC91_08175	COG0587	DNA-directed DNA polymerase activity
LCC91_08180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCC91_08185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCC91_08225	COG0737	Belongs to the 5'-nucleotidase family
LCC91_08245	COG4654	Cytochrome c, class I
LCC91_08250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LCC91_08255	COG0640	Transcriptional regulator
LCC91_08260	COG1136	(ABC) transporter
LCC91_08280	COG0564	pseudouridine synthase activity
LCC91_08295	COG1752	Esterase of the alpha-beta hydrolase superfamily
LCC91_08300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LCC91_08310	COG4566	intracellular signal transduction
LCC91_08335	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LCC91_08335	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LCC91_08345	COG3022	response to hydroperoxide
LCC91_08380	COG1518	maintenance of DNA repeat elements
LCC91_08415	COG0247	lactate metabolic process
LCC91_08420	COG1592	Rubrerythrin
LCC91_08425	COG0525	valine-tRNA ligase activity
LCC91_08430	COG0425	Belongs to the sulfur carrier protein TusA family
LCC91_08455	COG1999	signal sequence binding
LCC91_08460	COG0109	protoheme IX farnesyltransferase activity
LCC91_08465	COG1612	heme a metabolic process
LCC91_08485	COG1845	cytochrome c oxidase, subunit III
LCC91_08495	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LCC91_08505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LCC91_08520	COG2226	methyltransferase
LCC91_08525	COG1040	competence protein
LCC91_08530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LCC91_08545	COG0741	lytic transglycosylase activity
LCC91_08550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LCC91_08555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCC91_08560	COG3275	phosphorelay sensor kinase activity
LCC91_08620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LCC91_08625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCC91_08630	COG0824	Thioesterase
LCC91_08650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCC91_08670	COG1741	Belongs to the pirin family
LCC91_08675	COG0583	DNA-binding transcription factor activity
LCC91_08680	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LCC91_08685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCC91_08690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LCC91_08695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCC91_08695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCC91_08700	COG0564	pseudouridine synthase activity
LCC91_08720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCC91_08725	COG2070	2-Nitropropane dioxygenase
LCC91_08750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCC91_08835	COG0438	transferase activity, transferring glycosyl groups
LCC91_08860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LCC91_08870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCC91_08890	COG4636	protein conserved in cyanobacteria
LCC91_08895	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LCC91_08900	COG1047	Peptidyl-prolyl cis-trans
LCC91_08905	COG2003	Belongs to the UPF0758 family
LCC91_08920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LCC91_08925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LCC91_08945	COG0437	4 iron, 4 sulfur cluster binding
LCC91_08950	COG0243	molybdopterin cofactor binding
LCC91_08950	COG3383	formate dehydrogenase (NAD+) activity
LCC91_08965	COG3852	Histidine kinase
LCC91_08990	COG0489	protein tyrosine kinase activity
LCC91_08995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCC91_08995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCC91_09000	COG0659	secondary active sulfate transmembrane transporter activity
LCC91_09015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LCC91_09030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCC91_09035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCC91_09070	COG3278	Belongs to the heme-copper respiratory oxidase family
LCC91_09085	COG0589	response to stress
LCC91_09090	COG0318	PFAM AMP-dependent synthetase and ligase
LCC91_09095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCC91_09105	COG0129	dihydroxy-acid dehydratase activity
LCC91_09115	COG4654	Cytochrome c, class I
LCC91_09120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCC91_09140	COG3549	Plasmid maintenance system killer
LCC91_09155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCC91_09155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCC91_09160	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LCC91_09165	COG1238	metal cluster binding
LCC91_09175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCC91_09180	COG1960	acyl-CoA dehydrogenase activity
LCC91_09185	COG1960	acyl-CoA dehydrogenase activity
LCC91_09210	COG0196	riboflavin kinase activity
LCC91_09215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCC91_09220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCC91_09225	COG0840	transmembrane signaling receptor activity
LCC91_09255	COG1028	Short-chain dehydrogenase reductase Sdr
LCC91_09285	COG0084	hydrolase, TatD family'
LCC91_09290	COG3181	Tripartite tricarboxylate transporter family receptor
LCC91_09305	COG0604	alcohol dehydrogenase
LCC91_09310	COG0318	PFAM AMP-dependent synthetase and ligase
LCC91_09315	COG2814	Major facilitator Superfamily
LCC91_09345	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LCC91_09355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LCC91_09430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCC91_09430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCC91_09445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LCC91_09450	COG1744	ABC transporter substrate-binding protein PnrA-like
LCC91_09455	COG1609	Transcriptional regulator
LCC91_09460	COG3845	ABC transporter
LCC91_09465	COG4603	Belongs to the binding-protein-dependent transport system permease family
LCC91_09470	COG1079	Belongs to the binding-protein-dependent transport system permease family
LCC91_09475	COG0295	cytidine deaminase activity
LCC91_09480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LCC91_09485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCC91_09495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCC91_09505	COG2264	protein methyltransferase activity
LCC91_09510	COG0439	Biotin carboxylase
LCC91_09515	COG0511	ligase activity, forming carbon-carbon bonds
LCC91_09530	COG0745	RESPONSE REGULATOR receiver
LCC91_09535	COG0745	RESPONSE REGULATOR receiver
LCC91_09575	COG0540	Belongs to the ATCase OTCase family
LCC91_09580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCC91_09585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCC91_09590	COG1678	Uncharacterized ACR, COG1678
LCC91_09595	COG0415	Belongs to the DNA photolyase family
LCC91_09615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LCC91_09620	COG4242	Belongs to the peptidase S51 family
LCC91_09625	COG0826	peptidase U32
LCC91_09630	COG1049	propionate catabolic process, 2-methylcitrate cycle
LCC91_09640	COG0039	L-malate dehydrogenase activity
LCC91_09645	COG2188	Transcriptional regulator
LCC91_09660	COG1053	succinate dehydrogenase
LCC91_09665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LCC91_09670	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LCC91_09675	COG0372	Belongs to the citrate synthase family
LCC91_09680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCC91_09690	COG0066	3-isopropylmalate dehydratase activity
LCC91_09695	COG0473	3-isopropylmalate dehydrogenase activity
LCC91_09715	COG0101	tRNA pseudouridine synthase activity
LCC91_09720	COG0135	phosphoribosylanthranilate isomerase activity
LCC91_09725	COG0133	tryptophan synthase activity
LCC91_09730	COG0159	tryptophan synthase activity
LCC91_09735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LCC91_09765	COG0736	holo-[acyl-carrier-protein] synthase activity
LCC91_09770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LCC91_09775	COG1381	Involved in DNA repair and RecF pathway recombination
LCC91_09780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCC91_09785	COG0571	ribonuclease III activity
LCC91_09800	COG0481	GTPase activity
LCC91_09805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCC91_09830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCC91_09835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCC91_09840	COG1028	Short-chain dehydrogenase reductase Sdr
LCC91_09850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCC91_09855	COG0416	fatty acid biosynthetic process
LCC91_09860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LCC91_09865	COG1399	metal-binding, possibly nucleic acid-binding protein
LCC91_09870	COG0259	pyridoxamine-phosphate oxidase activity
LCC91_09875	COG2161	toxin-antitoxin pair type II binding
LCC91_09880	COG4115	mRNA cleavage
LCC91_09890	COG0617	tRNA 3'-terminal CCA addition
LCC91_09905	COG0628	permease
LCC91_09910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LCC91_09920	COG0728	peptidoglycan biosynthetic process
LCC91_09925	COG0613	PHP domain protein
LCC91_09930	COG0009	L-threonylcarbamoyladenylate synthase
LCC91_09935	COG1994	Peptidase M50
LCC91_09940	COG0180	Tryptophanyl-tRNA synthetase
LCC91_09995	COG0582	viral genome integration into host DNA
LCC91_10005	COG2969	positive regulation of protein catabolic process
LCC91_10010	COG0625	glutathione transferase activity
LCC91_10015	COG2857	Cytochrome c1
LCC91_10020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LCC91_10025	COG0723	plastoquinol--plastocyanin reductase activity
LCC91_10030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LCC91_10035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCC91_10045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCC91_10050	COG0805	protein transport
LCC91_10055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LCC91_10060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LCC91_10065	COG0537	adenosine 5'-monophosphoramidase activity
LCC91_10075	COG0140	phosphoribosyl-ATP diphosphatase activity
LCC91_10080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LCC91_10085	COG0107	imidazoleglycerol-phosphate synthase activity
LCC91_10090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LCC91_10100	COG0131	Imidazoleglycerol-phosphate dehydratase
LCC91_10105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCC91_10115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LCC91_10120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCC91_10125	COG0271	Belongs to the BolA IbaG family
LCC91_10130	COG0842	Transport permease protein
LCC91_10135	COG1131	(ABC) transporter
LCC91_10150	COG2853	Lipoprotein
LCC91_10155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LCC91_10160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LCC91_10165	COG1127	ABC transporter
LCC91_10175	COG0069	glutamate synthase activity
LCC91_10175	COG0067	glutamate synthase
LCC91_10175	COG0070	glutamate synthase
LCC91_10185	COG2271	Major facilitator Superfamily
LCC91_10190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LCC91_10195	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LCC91_10200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LCC91_10240	COG1965	Belongs to the frataxin family
LCC91_10255	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LCC91_10260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LCC91_10265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LCC91_10270	COG1333	cytochrome c biogenesis protein
LCC91_10280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LCC91_10295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCC91_10310	COG0739	heme binding
LCC91_10310	COG1196	nuclear chromosome segregation
LCC91_10310	COG0741	lytic transglycosylase activity
LCC91_10320	COG0463	Glycosyl transferase, family 2
LCC91_10330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LCC91_10330	COG2755	lipolytic protein G-D-S-L family
LCC91_10360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCC91_10375	COG1450	Type ii and iii secretion system protein
LCC91_10405	COG2165	general secretion pathway protein
LCC91_10415	COG2165	general secretion pathway protein
LCC91_10425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCC91_10480	COG0243	molybdopterin cofactor binding
LCC91_10485	COG1473	amidohydrolase
LCC91_10490	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LCC91_10505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LCC91_10505	COG1703	isobutyryl-CoA mutase activity
LCC91_10505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LCC91_10520	COG0739	heme binding
LCC91_10520	COG0741	lytic transglycosylase activity
LCC91_10520	COG1196	nuclear chromosome segregation
LCC91_10530	COG1937	Protein conserved in bacteria
LCC91_10535	COG0617	tRNA 3'-terminal CCA addition
LCC91_10565	COG0037	tRNA processing
LCC91_10575	COG0784	Response regulator, receiver
LCC91_10575	COG0835	chemotaxis
LCC91_10585	COG2255	four-way junction helicase activity
LCC91_10590	COG0632	four-way junction helicase activity
LCC91_10595	COG1702	phosphate starvation-inducible protein PhoH
LCC91_10600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LCC91_10605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCC91_10610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCC91_10620	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LCC91_10625	COG0316	Belongs to the HesB IscA family
LCC91_10630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LCC91_10635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCC91_10640	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LCC91_10645	COG0840	transmembrane signaling receptor activity
LCC91_10655	COG5464	transposase or invertase
LCC91_10660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LCC91_10670	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LCC91_10675	COG0142	geranyltranstransferase activity
LCC91_10685	COG4302	ethanolamine ammonia-lyase activity
LCC91_10695	COG0531	amino acid
LCC91_10720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCC91_10730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LCC91_10740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LCC91_10745	COG0312	modulator of DNA gyrase
LCC91_10750	COG0772	Belongs to the SEDS family
LCC91_10755	COG3150	esterase
LCC91_10765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LCC91_10770	COG0557	exoribonuclease II activity
LCC91_10780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCC91_10785	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LCC91_10795	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LCC91_10800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCC91_10815	COG1181	Belongs to the D-alanine--D-alanine ligase family
LCC91_10820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LCC91_10825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCC91_10830	COG0772	Belongs to the SEDS family
LCC91_10835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCC91_10840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCC91_10845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCC91_10850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCC91_10865	COG0275	rRNA processing
LCC91_10870	COG2001	Belongs to the MraZ family
LCC91_10875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LCC91_10880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LCC91_10895	COG0523	cobalamin synthesis protein
LCC91_10900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LCC91_10910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LCC91_10920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LCC91_10950	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LCC91_10955	COG0501	Belongs to the peptidase M48B family
LCC91_10970	COG0642	Histidine kinase
LCC91_10990	COG0418	dihydroorotase activity
LCC91_10995	COG1126	abc transporter atp-binding protein
LCC91_11000	COG0765	amino acid transport
LCC91_11005	COG0765	amino acid transport
LCC91_11010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCC91_11020	COG5265	(ABC) transporter
LCC91_11040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCC91_11045	COG1028	Short-chain dehydrogenase reductase Sdr
LCC91_11050	COG1522	sequence-specific DNA binding
LCC91_11075	COG3186	Phenylalanine-4-hydroxylase
LCC91_11095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LCC91_11100	COG3047	cAMP biosynthetic process
LCC91_11110	COG1686	Belongs to the peptidase S11 family
LCC91_11130	COG1981	membrane
LCC91_11135	COG0277	FAD linked oxidase domain protein
LCC91_11140	COG0247	lactate metabolic process
LCC91_11150	COG3181	Tripartite tricarboxylate transporter family receptor
LCC91_11160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCC91_11215	COG2198	Histidine kinase
LCC91_11215	COG0643	Histidine kinase
LCC91_11220	COG0840	transmembrane signaling receptor activity
LCC91_11245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LCC91_11250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCC91_11295	COG0482	sulfurtransferase activity
LCC91_11305	COG2346	COG2346, Truncated hemoglobins
LCC91_11310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LCC91_11330	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LCC91_11335	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LCC91_11350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LCC91_11365	COG2814	Major facilitator Superfamily
LCC91_11370	COG0840	transmembrane signaling receptor activity
LCC91_11375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCC91_11395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LCC91_11400	COG1546	Belongs to the CinA family
LCC91_11400	COG1058	Belongs to the CinA family
LCC91_11405	COG3318	Belongs to the UPF0149 family
LCC91_11405	COG3012	SEC-C Motif Domain Protein
LCC91_11410	COG1067	ATP-dependent peptidase activity
LCC91_11440	COG0006	proline dipeptidase activity
LCC91_11445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LCC91_11455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LCC91_11480	COG0840	transmembrane signaling receptor activity
LCC91_11490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCC91_11495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCC91_11515	COG2233	PERMEase
LCC91_11550	COG4453	Protein conserved in bacteria
LCC91_11580	COG4942	peptidase
LCC91_11590	COG3077	Addiction module antitoxin, RelB DinJ family
LCC91_11600	COG0456	acetyltransferase
LCC91_11605	COG1573	uracil-dna glycosylase
LCC91_11610	COG4608	Belongs to the ABC transporter superfamily
LCC91_11615	COG0444	Belongs to the ABC transporter superfamily
LCC91_11620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCC91_11625	COG0601	transmembrane transport
LCC91_11630	COG4166	transmembrane transport
LCC91_11640	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LCC91_11655	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LCC91_11660	COG0386	Belongs to the glutathione peroxidase family
LCC91_11665	COG0791	NLP P60 protein
LCC91_11670	COG1466	dna polymerase III delta subunit
LCC91_11695	COG0495	leucyl-tRNA aminoacylation
LCC91_11710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LCC91_11715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LCC91_11720	COG0735	belongs to the Fur family
LCC91_11725	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LCC91_11735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LCC91_11750	COG3220	belongs to the UPF0276 family
LCC91_11770	COG1595	DNA-templated transcription, initiation
LCC91_11785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LCC91_11785	COG2199	diguanylate cyclase activity
LCC91_11795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LCC91_11805	COG0598	Magnesium transport protein CorA
LCC91_11810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCC91_11815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCC91_11820	COG0318	PFAM AMP-dependent synthetase and ligase
LCC91_11850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LCC91_11865	COG1011	Hydrolase
LCC91_11870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCC91_11880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LCC91_11885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCC91_11890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCC91_11940	COG3706	GGDEF domain
LCC91_11955	COG1704	LemA family
LCC91_11960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LCC91_11965	COG1984	allophanate hydrolase subunit 2
LCC91_11970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LCC91_12000	COG1271	oxidase subunit
LCC91_12005	COG1294	oxidase, subunit
LCC91_12015	COG1136	(ABC) transporter
LCC91_12020	COG4591	ABC-type transport system involved in lipoprotein release permease component
LCC91_12030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LCC91_12060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCC91_12065	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LCC91_12075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LCC91_12080	COG2205	protein histidine kinase activity
LCC91_12100	COG3118	belongs to the thioredoxin family
LCC91_12105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCC91_12110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCC91_12115	COG0009	L-threonylcarbamoyladenylate synthase
LCC91_12125	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LCC91_12135	COG0850	regulation of cytokinetic process
LCC91_12140	COG2217	Heavy metal translocating P-type atpase
LCC91_12145	COG2217	Heavy metal translocating P-type atpase
LCC91_12155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LCC91_12170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCC91_12180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LCC91_12185	COG0174	glutamine synthetase
LCC91_12200	COG3842	ATPase activity
LCC91_12205	COG1176	ABC-type spermidine putrescine transport system, permease component I
LCC91_12210	COG1177	transmembrane transport
LCC91_12220	COG1012	belongs to the aldehyde dehydrogenase family
LCC91_12225	COG1902	pentaerythritol trinitrate reductase activity
LCC91_12240	COG0840	transmembrane signaling receptor activity
LCC91_12280	COG0445	tRNA wobble uridine modification
LCC91_12285	COG0357	Ribosomal RNA small subunit methyltransferase G
LCC91_12295	COG1192	Involved in chromosome partitioning
LCC91_12300	COG1475	DNA binding
LCC91_12315	COG0277	FAD linked oxidase domain protein
LCC91_12320	COG2096	Adenosyltransferase
LCC91_12335	COG3327	negative regulation of DNA-templated transcription, initiation
LCC91_12340	COG2050	protein possibly involved in aromatic compounds catabolism
LCC91_12350	COG3396	Phenylacetate-CoA oxygenase
LCC91_12355	COG3460	Phenylacetate-CoA oxygenase
LCC91_12360	COG3396	Phenylacetate-CoA oxygenase
LCC91_12365	COG2151	metal-sulfur cluster biosynthetic enzyme
LCC91_12370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LCC91_12395	COG1012	belongs to the aldehyde dehydrogenase family
LCC91_12395	COG2030	dehydratase
LCC91_12410	COG0183	Belongs to the thiolase family
LCC91_12420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LCC91_12425	COG1137	ATPase activity
LCC91_12435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LCC91_12445	COG0018	arginyl-trna synthetase
LCC91_12450	COG0010	Belongs to the arginase family
LCC91_12480	COG3842	ATPase activity
LCC91_12485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LCC91_12500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LCC91_12505	COG4691	Plasmid stability protein
LCC91_12515	COG0583	DNA-binding transcription factor activity
LCC91_12520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LCC91_12550	COG0514	ATP-dependent DNA helicase (RecQ)
LCC91_12570	COG0783	Belongs to the Dps family
LCC91_12575	COG1858	cytochrome C peroxidase
LCC91_12620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCC91_12625	COG0343	queuine tRNA-ribosyltransferase activity
LCC91_12640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCC91_12655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCC91_12665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LCC91_12675	COG1115	amino acid carrier protein
LCC91_12680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LCC91_12685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCC91_12690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCC91_12695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCC91_12700	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCC91_12705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LCC91_12710	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LCC91_12715	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LCC91_12720	COG1841	ribosomal large subunit assembly
LCC91_12725	COG0200	Binds to the 23S rRNA
LCC91_12730	COG0201	protein transport
LCC91_12740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LCC91_12745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LCC91_12750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCC91_12755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCC91_12760	COG0202	RNA polymerase activity
LCC91_12765	COG0203	ribosomal protein L17
LCC91_12775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LCC91_12780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCC91_12785	COG1653	transport
LCC91_12790	COG1175	transmembrane transport
LCC91_12795	COG0395	ABC-type sugar transport system, permease component
LCC91_12805	COG0673	inositol 2-dehydrogenase activity
LCC91_12810	COG0837	glucose binding
LCC91_12815	COG1737	Transcriptional regulator
LCC91_12820	COG0166	Belongs to the GPI family
LCC91_12825	COG0800	Aldolase
LCC91_12840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCC91_12845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCC91_12880	COG2095	MarC family integral membrane protein
LCC91_12890	COG0697	spore germination
LCC91_12895	COG1862	Preprotein translocase
LCC91_12900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCC91_12905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCC91_12910	COG0758	DNA mediated transformation
LCC91_12920	COG0242	peptide deformylase activity
LCC91_12925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCC91_12940	COG0784	Response regulator, receiver
LCC91_12940	COG2198	Histidine kinase
LCC91_12940	COG2205	protein histidine kinase activity
LCC91_12950	COG0210	DNA helicase
LCC91_12960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCC91_12965	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LCC91_12975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCC91_12995	COG0488	(ABC) transporter
LCC91_13100	COG3158	transport of potassium into the cell
LCC91_13140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCC91_13145	COG0326	Molecular chaperone. Has ATPase activity
LCC91_13150	COG1764	response to oxidative stress
LCC91_13155	COG1846	Transcriptional regulator
LCC91_13190	COG0842	Transport permease protein
LCC91_13195	COG1131	(ABC) transporter
LCC91_13215	COG0688	phosphatidylethanolamine metabolic process
LCC91_13220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCC91_13245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCC91_13250	COG0134	indole-3-glycerol-phosphate synthase activity
LCC91_13295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LCC91_13300	COG0081	regulation of translation
LCC91_13305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LCC91_13310	COG0222	ribosome binding
LCC91_13315	COG0085	RNA polymerase activity
LCC91_13320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCC91_13325	COG1704	LemA family
LCC91_13330	COG0501	Belongs to the peptidase M48B family
LCC91_13335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCC91_13345	COG5000	phosphorelay sensor kinase activity
LCC91_13350	COG2204	response regulator
LCC91_13455	COG5002	protein histidine kinase activity
LCC91_13495	COG2217	Heavy metal translocating P-type atpase
LCC91_13525	COG0708	Exodeoxyribonuclease III
LCC91_13530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCC91_13535	COG0049	tRNA binding
LCC91_13540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCC91_13550	COG0051	transcription antitermination factor activity, RNA binding
LCC91_13555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCC91_13560	COG0088	Forms part of the polypeptide exit tunnel
LCC91_13565	COG0089	rRNA binding
LCC91_13570	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCC91_13575	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LCC91_13580	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCC91_13585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LCC91_13590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LCC91_13595	COG0255	Belongs to the universal ribosomal protein uL29 family
LCC91_13600	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCC91_13605	COG0678	peroxiredoxin activity
LCC91_13635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCC91_13645	COG5002	protein histidine kinase activity
LCC91_13645	COG2205	protein histidine kinase activity
LCC91_13645	COG0784	Response regulator, receiver
LCC91_13650	COG2203	Gaf domain
LCC91_13650	COG3706	GGDEF domain
LCC91_13650	COG4251	negative regulation of phosphorylation
LCC91_13650	COG5001	Diguanylate cyclase
LCC91_13670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCC91_13675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCC91_13680	COG3744	PilT protein domain protein
LCC91_13710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LCC91_13725	COG1793	dna ligase
LCC91_13725	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LCC91_13730	COG1793	dna ligase
LCC91_13735	COG1201	RNA secondary structure unwinding
LCC91_13750	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LCC91_13750	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LCC91_13755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCC91_13755	COG0551	DNA topoisomerase type I activity
LCC91_13760	COG0625	glutathione transferase activity
LCC91_13765	COG0642	Histidine kinase
LCC91_13780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCC91_13785	COG2137	regulation of response to DNA damage stimulus
LCC91_13790	COG0840	transmembrane signaling receptor activity
LCC91_13795	COG0436	Aminotransferase
LCC91_13800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCC91_13805	COG0706	membrane insertase activity
LCC91_13810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LCC91_13820	COG0230	Belongs to the bacterial ribosomal protein bL34 family