locus-tag	class	description
OSSY52_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OSSY52_00020	COG1063	alcohol dehydrogenase
OSSY52_00030	COG0156	8-amino-7-oxononanoate synthase activity
OSSY52_00040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OSSY52_00070	COG1309	transcriptional regulator
OSSY52_00100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OSSY52_00110	COG0242	peptide deformylase activity
OSSY52_00120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OSSY52_00140	COG0489	protein tyrosine kinase activity
OSSY52_00160	COG2813	Specifically methylates the guanine in position
OSSY52_00180	COG1122	ATPase activity
OSSY52_00210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OSSY52_00220	COG2086	electron transfer activity
OSSY52_00230	COG1960	acyl-CoA dehydrogenase activity
OSSY52_00270	COG3328	transposase activity
OSSY52_00290	COG3328	transposase activity
OSSY52_00300	COG3328	transposase activity
OSSY52_00320	COG3328	transposase activity
OSSY52_00360	COG0641	radical SAM
OSSY52_00440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OSSY52_00500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OSSY52_00550	COG0084	hydrolase, TatD family'
OSSY52_00560	COG0561	phosphatase activity
OSSY52_00590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OSSY52_00630	COG1131	(ABC) transporter
OSSY52_00670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OSSY52_00680	COG0191	fructose-bisphosphate aldolase activity
OSSY52_00690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OSSY52_00710	COG0534	Mate efflux family protein
OSSY52_00720	COG4716	Myosin-crossreactive antigen
OSSY52_00740	COG0697	spore germination
OSSY52_00780	COG1278	Cold shock
OSSY52_00790	COG1278	Cold shock
OSSY52_00810	COG1706	bacterial-type flagellum-dependent cell motility
OSSY52_00840	COG4786	Flagellar basal body rod
OSSY52_00850	COG4786	Flagellar basal body rod
OSSY52_00860	COG1077	Cell shape determining protein MreB Mrl
OSSY52_00870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OSSY52_00890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OSSY52_00890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OSSY52_00900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OSSY52_00920	COG0628	permease
OSSY52_00950	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OSSY52_00990	COG1131	(ABC) transporter
OSSY52_01000	COG3437	response regulator, receiver
OSSY52_01030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OSSY52_01060	COG1802	Transcriptional regulator
OSSY52_01070	COG1013	pyruvate-flavodoxin oxidoreductase activity
OSSY52_01080	COG0674	pyruvate-flavodoxin oxidoreductase activity
OSSY52_01090	COG1144	Oxidoreductase
OSSY52_01170	COG1518	maintenance of DNA repeat elements
OSSY52_01180	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OSSY52_01190	COG0017	Asparaginyl-tRNA synthetase
OSSY52_01200	COG0174	glutamine synthetase
OSSY52_01210	COG0138	bifunctional purine biosynthesis protein purh
OSSY52_01220	COG5002	protein histidine kinase activity
OSSY52_01220	COG5001	Diguanylate cyclase
OSSY52_01220	COG3447	MASE1 domain protein
OSSY52_01240	COG1309	transcriptional regulator
OSSY52_01260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OSSY52_01270	COG4608	Belongs to the ABC transporter superfamily
OSSY52_01280	COG0444	Belongs to the ABC transporter superfamily
OSSY52_01290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OSSY52_01300	COG0601	transmembrane transport
OSSY52_01310	COG0747	negative chemotaxis
OSSY52_01330	COG0564	pseudouridine synthase activity
OSSY52_01360	COG0436	Aminotransferase
OSSY52_01440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OSSY52_01450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSSY52_01460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OSSY52_01480	COG0402	S-adenosylhomocysteine deaminase activity
OSSY52_01490	COG0167	dihydroorotate dehydrogenase activity
OSSY52_01530	COG0733	neurotransmitter:sodium symporter activity
OSSY52_01540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OSSY52_01550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OSSY52_01560	COG1862	Preprotein translocase
OSSY52_01590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OSSY52_01590	COG0574	Belongs to the PEP-utilizing enzyme family
OSSY52_01600	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OSSY52_01620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OSSY52_01620	COG0674	pyruvate-flavodoxin oxidoreductase activity
OSSY52_01630	COG2199	diguanylate cyclase activity
OSSY52_01630	COG2203	Gaf domain
OSSY52_01640	COG2359	stage V sporulation protein S
OSSY52_01660	COG3872	metal-dependent enzyme
OSSY52_01670	COG3279	Response regulator of the LytR AlgR family
OSSY52_01680	COG3275	phosphorelay sensor kinase activity
OSSY52_01700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OSSY52_01720	COG0758	DNA mediated transformation
OSSY52_01720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OSSY52_01750	COG1847	R3H domain protein
OSSY52_01760	COG0706	membrane insertase activity
OSSY52_01770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OSSY52_01780	COG0594	ribonuclease P activity
OSSY52_01790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OSSY52_01810	COG0737	Belongs to the 5'-nucleotidase family
OSSY52_01830	COG0840	transmembrane signaling receptor activity
OSSY52_01850	COG0840	transmembrane signaling receptor activity
OSSY52_01890	COG0674	pyruvate-flavodoxin oxidoreductase activity
OSSY52_01920	COG3426	butyrate kinase activity
OSSY52_01930	COG0280	phosphate acetyltransferase
OSSY52_01940	COG3426	butyrate kinase activity
OSSY52_01950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSSY52_01960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OSSY52_01970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OSSY52_02070	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSSY52_02090	COG1132	(ABC) transporter
OSSY52_02140	COG3842	ATPase activity
OSSY52_02170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OSSY52_02180	COG0535	radical SAM domain protein
OSSY52_02240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OSSY52_02250	COG2205	protein histidine kinase activity
OSSY52_02310	COG1758	RNA polymerase activity
OSSY52_02320	COG0194	GDP metabolic process
OSSY52_02330	COG2052	Domain of unknown function (DUF370)
OSSY52_02340	COG1561	YicC-like family, N-terminal region
OSSY52_02350	COG1104	cysteine desulfurase activity
OSSY52_02360	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OSSY52_02370	COG0509	glycine decarboxylation via glycine cleavage system
OSSY52_02390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSSY52_02390	COG0072	phenylalanine-tRNA ligase activity
OSSY52_02400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OSSY52_02440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OSSY52_02450	COG0488	(ABC) transporter
OSSY52_02470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSSY52_02500	COG1136	(ABC) transporter
OSSY52_02510	COG5002	protein histidine kinase activity
OSSY52_02520	COG0745	RESPONSE REGULATOR receiver
OSSY52_02540	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSSY52_02550	COG0542	response to heat
OSSY52_02560	COG3864	Putative metallopeptidase domain
OSSY52_02580	COG1136	(ABC) transporter
OSSY52_02600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OSSY52_02610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OSSY52_02620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OSSY52_02630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OSSY52_02640	COG2203	Gaf domain
OSSY52_02640	COG2199	diguanylate cyclase activity
OSSY52_02650	COG0653	protein targeting
OSSY52_02670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OSSY52_02690	COG1376	ErfK ybiS ycfS ynhG family protein
OSSY52_02700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OSSY52_02710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OSSY52_02730	COG1137	ATPase activity
OSSY52_02760	COG1543	Belongs to the glycosyl hydrolase 57 family
OSSY52_02770	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OSSY52_02780	COG1144	Oxidoreductase
OSSY52_02790	COG0674	pyruvate-flavodoxin oxidoreductase activity
OSSY52_02800	COG1013	pyruvate-flavodoxin oxidoreductase activity
OSSY52_02810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSSY52_02820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OSSY52_02830	COG3328	transposase activity
OSSY52_02840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OSSY52_02850	COG2205	protein histidine kinase activity
OSSY52_02870	COG0432	Pfam Uncharacterised protein family UPF0047
OSSY52_02890	COG2894	cell division
OSSY52_02920	COG1131	(ABC) transporter
OSSY52_02940	COG3706	GGDEF domain
OSSY52_02950	COG1404	Belongs to the peptidase S8 family
OSSY52_03070	COG0343	queuine tRNA-ribosyltransferase activity
OSSY52_03160	COG0438	transferase activity, transferring glycosyl groups
OSSY52_03220	COG0438	transferase activity, transferring glycosyl groups
OSSY52_03240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OSSY52_03260	COG0776	regulation of translation
OSSY52_03300	COG0840	transmembrane signaling receptor activity
OSSY52_03330	COG1307	EDD domain protein, DegV family
OSSY52_03340	COG3341	Caulimovirus viroplasmin
OSSY52_03340	COG0328	RNA-DNA hybrid ribonuclease activity
OSSY52_03360	COG0534	Mate efflux family protein
OSSY52_03370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSSY52_03380	COG1272	protein, Hemolysin III
OSSY52_03390	COG0071	Belongs to the small heat shock protein (HSP20) family
OSSY52_03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSSY52_03420	COG0281	malic enzyme
OSSY52_03430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OSSY52_03430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OSSY52_03500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OSSY52_03510	COG1215	transferase activity, transferring glycosyl groups
OSSY52_03530	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OSSY52_03540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSSY52_03560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OSSY52_03580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSSY52_03590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSSY52_03600	COG1216	Glycosyl transferase, family 2
OSSY52_03600	COG0463	Glycosyl transferase, family 2
OSSY52_03620	COG0463	Glycosyl transferase, family 2
OSSY52_03720	COG1215	transferase activity, transferring glycosyl groups
OSSY52_03750	COG1088	dTDP-glucose 4,6-dehydratase activity
OSSY52_03860	COG3404	Formiminotransferase-cyclodeaminase
OSSY52_03890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OSSY52_03920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OSSY52_03940	COG5012	cobalamin binding
OSSY52_03980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OSSY52_03990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSSY52_04010	COG0779	Required for maturation of 30S ribosomal subunits
OSSY52_04020	COG0195	Participates in both transcription termination and antitermination
OSSY52_04050	COG0708	Exodeoxyribonuclease III
OSSY52_04060	COG1966	Carbon starvation protein
OSSY52_04080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OSSY52_04090	COG3842	ATPase activity
OSSY52_04100	COG0546	phosphoglycolate phosphatase activity
OSSY52_04110	COG0513	Belongs to the DEAD box helicase family
OSSY52_04150	COG1410	methionine synthase
OSSY52_04150	COG0646	methionine synthase
OSSY52_04200	COG0527	aspartate kinase activity
OSSY52_04210	COG2310	stress, protein
OSSY52_04220	COG2310	stress, protein
OSSY52_04230	COG0530	calcium, potassium:sodium antiporter activity
OSSY52_04240	COG2310	stress, protein
OSSY52_04260	COG3853	Toxic anion resistance protein (TelA)
OSSY52_04280	COG0784	Response regulator, receiver
OSSY52_04280	COG3437	response regulator, receiver
OSSY52_04290	COG0006	proline dipeptidase activity
OSSY52_04300	COG1074	ATP-dependent DNA helicase activity
OSSY52_04320	COG1406	Chemotaxis phosphatase CheX
OSSY52_04330	COG0549	Belongs to the carbamate kinase family
OSSY52_04340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OSSY52_04350	COG2235	arginine
OSSY52_04360	COG2379	hydroxypyruvate reductase
OSSY52_04410	COG0395	ABC-type sugar transport system, permease component
OSSY52_04420	COG1175	transmembrane transport
OSSY52_04440	COG0438	transferase activity, transferring glycosyl groups
OSSY52_04500	COG0745	RESPONSE REGULATOR receiver
OSSY52_04510	COG3850	Histidine kinase
OSSY52_04510	COG5002	protein histidine kinase activity
OSSY52_04520	COG1363	Peptidase, m42
OSSY52_04590	COG1028	Short-chain dehydrogenase reductase Sdr
OSSY52_04600	COG1406	Chemotaxis phosphatase CheX
OSSY52_04610	COG2226	methyltransferase
OSSY52_04620	COG0306	phosphate transporter
OSSY52_04630	COG1392	Phosphate transport regulator
OSSY52_04640	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OSSY52_04670	COG3681	Belongs to the UPF0597 family
OSSY52_04730	COG0792	nuclease activity
OSSY52_04740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OSSY52_04800	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
OSSY52_04820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OSSY52_04830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OSSY52_04840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OSSY52_04850	COG3437	response regulator, receiver
OSSY52_04860	COG0840	transmembrane signaling receptor activity
OSSY52_04880	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSSY52_04880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OSSY52_04900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSSY52_04910	COG1012	belongs to the aldehyde dehydrogenase family
OSSY52_04920	COG1132	(ABC) transporter
OSSY52_04930	COG1132	(ABC) transporter
OSSY52_05000	COG0215	cysteine-tRNA ligase activity
OSSY52_05010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OSSY52_05050	COG4536	flavin adenine dinucleotide binding
OSSY52_05060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSSY52_05070	COG0484	heat shock protein binding
OSSY52_05080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OSSY52_05090	COG1420	regulation of RNA biosynthetic process
OSSY52_05100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OSSY52_05110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OSSY52_05120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OSSY52_05130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OSSY52_05140	COG0772	Belongs to the SEDS family
OSSY52_05150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OSSY52_05160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OSSY52_05170	COG3328	transposase activity
OSSY52_05260	COG1355	regulation of microtubule-based process
OSSY52_05280	COG1461	Dihydroxyacetone kinase
OSSY52_05290	COG0752	glycyl-tRNA synthetase alpha subunit
OSSY52_05330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OSSY52_05340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OSSY52_05350	COG0840	transmembrane signaling receptor activity
OSSY52_05350	COG5278	phosphoserine phosphatase activity
OSSY52_05360	COG1051	belongs to the nudix hydrolase family
OSSY52_05390	COG1484	DNA-dependent DNA replication
OSSY52_05400	COG3328	transposase activity
OSSY52_05410	COG3328	transposase activity
OSSY52_05500	COG1811	Na channel or pump
OSSY52_05510	COG2195	Cleaves the N-terminal amino acid of tripeptides
OSSY52_05530	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSSY52_05550	COG3328	transposase activity
OSSY52_05580	COG1285	pathogenesis
OSSY52_05590	COG0183	Belongs to the thiolase family
OSSY52_05600	COG1028	Short-chain dehydrogenase reductase Sdr
OSSY52_05610	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OSSY52_05620	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OSSY52_05630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OSSY52_05650	COG2030	dehydratase
OSSY52_05670	COG0604	alcohol dehydrogenase
OSSY52_05680	COG3246	L-lysine catabolic process to acetate
OSSY52_05690	COG1607	acyl-coa hydrolase
OSSY52_05710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OSSY52_05730	COG0393	Putative heavy-metal-binding
OSSY52_05750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OSSY52_05760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OSSY52_05770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OSSY52_05780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OSSY52_05800	COG1660	Displays ATPase and GTPase activities
OSSY52_05810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OSSY52_05850	COG2359	stage V sporulation protein S
OSSY52_05880	COG4786	Flagellar basal body rod
OSSY52_05880	COG1256	bacterial-type flagellum assembly
OSSY52_05880	COG4786	Flagellar basal body rod
OSSY52_05880	COG1256	bacterial-type flagellum assembly
OSSY52_05890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSSY52_05910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OSSY52_05930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSSY52_05940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OSSY52_05950	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OSSY52_05960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OSSY52_05970	COG2137	regulation of response to DNA damage stimulus
OSSY52_05980	COG1193	negative regulation of DNA recombination
OSSY52_05980	COG1418	mRNA catabolic process
OSSY52_06030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OSSY52_06040	COG1160	GTP binding
OSSY52_06050	COG0539	negative regulation of cytoplasmic translation
OSSY52_06060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OSSY52_06070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OSSY52_06080	COG1366	Belongs to the anti-sigma-factor antagonist family
OSSY52_06090	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OSSY52_06110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OSSY52_06130	COG3850	Histidine kinase
OSSY52_06130	COG2205	protein histidine kinase activity
OSSY52_06130	COG3437	response regulator, receiver
OSSY52_06130	COG4999	Histidine kinase
OSSY52_06140	COG0193	aminoacyl-tRNA hydrolase activity
OSSY52_06150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OSSY52_06160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OSSY52_06170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OSSY52_06180	COG0632	four-way junction helicase activity
OSSY52_06190	COG0285	dihydrofolate synthase activity
OSSY52_06200	COG0525	valine-tRNA ligase activity
OSSY52_06230	COG3850	Histidine kinase
OSSY52_06230	COG3437	response regulator, receiver
OSSY52_06230	COG2205	protein histidine kinase activity
OSSY52_06230	COG4999	Histidine kinase
OSSY52_06250	COG1757	Na H antiporter
OSSY52_06280	COG4555	ABC transporter
OSSY52_06300	COG2045	Belongs to the ComB family
OSSY52_06340	COG3279	Response regulator of the LytR AlgR family
OSSY52_06350	COG3833	ABC-type maltose transport systems, permease component
OSSY52_06360	COG1175	transmembrane transport
OSSY52_06370	COG2182	Extracellular solute-binding protein
OSSY52_06380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OSSY52_06390	COG1215	transferase activity, transferring glycosyl groups
OSSY52_06400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OSSY52_06410	COG0728	peptidoglycan biosynthetic process
OSSY52_06430	COG3328	transposase activity
OSSY52_06440	COG3328	transposase activity
OSSY52_06450	COG3328	transposase activity
OSSY52_06460	COG3328	transposase activity
OSSY52_06500	COG0662	Cupin 2, conserved barrel domain protein
OSSY52_06500	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OSSY52_06510	COG1482	cell wall glycoprotein biosynthetic process
OSSY52_06520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OSSY52_06550	COG0822	iron-sulfur transferase activity
OSSY52_06560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OSSY52_06570	COG0719	Fe-S assembly protein
OSSY52_06580	COG0719	Fe-S assembly protein
OSSY52_06590	COG0396	ATPase activity
OSSY52_06620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OSSY52_06630	COG1307	EDD domain protein, DegV family
OSSY52_06640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OSSY52_06650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OSSY52_06670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OSSY52_06730	COG0542	response to heat
OSSY52_06770	COG0569	domain protein
OSSY52_06770	COG2985	domain, Protein
OSSY52_06790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OSSY52_06790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OSSY52_06800	COG1435	thymidine kinase activity
OSSY52_06840	COG4443	Transcriptional Coactivator p15 (PC4)
OSSY52_06870	COG1516	flagellar protein fliS
OSSY52_06900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OSSY52_06910	COG1086	Polysaccharide biosynthesis protein
OSSY52_06920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OSSY52_06940	COG0124	histidyl-tRNA synthetase
OSSY52_06950	COG1185	polyribonucleotide nucleotidyltransferase activity
OSSY52_06960	COG0254	rRNA binding
OSSY52_06990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OSSY52_07000	COG1584	GPR1 FUN34 yaaH family protein
OSSY52_07020	COG0477	Major facilitator Superfamily
OSSY52_07030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OSSY52_07040	COG0166	Belongs to the GPI family
OSSY52_07050	COG0237	dephospho-CoA kinase activity
OSSY52_07080	COG0322	excinuclease ABC activity
OSSY52_07100	COG2264	protein methyltransferase activity
OSSY52_07130	COG3337	CRISPR-associated protein (Cas_Cmr5)
OSSY52_07190	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OSSY52_07200	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OSSY52_07270	COG1937	Protein conserved in bacteria
OSSY52_07280	COG0793	Belongs to the peptidase S41A family
OSSY52_07340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OSSY52_07360	COG0640	Transcriptional regulator
OSSY52_07410	COG2081	HI0933 family
OSSY52_07420	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
OSSY52_07430	COG2195	Cleaves the N-terminal amino acid of tripeptides
OSSY52_07450	COG1358	cellular component organization or biogenesis
OSSY52_07490	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OSSY52_07490	COG0540	Belongs to the ATCase OTCase family
OSSY52_07510	COG2080	2 iron, 2 sulfur cluster binding
OSSY52_07520	COG2080	2 iron, 2 sulfur cluster binding
OSSY52_07520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OSSY52_07530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OSSY52_07550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OSSY52_07590	COG1979	alcohol dehydrogenase
OSSY52_07630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OSSY52_07650	COG0028	Belongs to the TPP enzyme family
OSSY52_07690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSSY52_07700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSSY52_07710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSSY52_07720	COG0457	Tetratricopeptide repeat
OSSY52_07720	COG0463	Glycosyl transferase, family 2
OSSY52_07730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OSSY52_07800	COG0101	tRNA pseudouridine synthase activity
OSSY52_07830	COG2226	methyltransferase
OSSY52_07850	COG1530	ribonuclease E activity
OSSY52_07860	COG3706	GGDEF domain
OSSY52_07880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OSSY52_07890	COG0233	cytoplasmic translational termination
OSSY52_07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OSSY52_07910	COG0575	Belongs to the CDS family
OSSY52_07930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OSSY52_07940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSSY52_07950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OSSY52_07970	COG1085	galactose-1-phosphate uridylyltransferase
OSSY52_07980	COG0297	glycogen (starch) synthase activity
OSSY52_08020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OSSY52_08030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OSSY52_08060	COG3328	transposase activity
OSSY52_08100	COG1131	(ABC) transporter
OSSY52_08150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OSSY52_08160	COG0228	four-way junction DNA binding
OSSY52_08170	COG1837	Belongs to the UPF0109 family
OSSY52_08180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OSSY52_08190	COG0336	Belongs to the RNA methyltransferase TrmD family
OSSY52_08200	COG4752	Belongs to the RNA methyltransferase TrmD family
OSSY52_08210	COG0335	large ribosomal subunit rRNA binding
OSSY52_08220	COG0681	Belongs to the peptidase S26 family
OSSY52_08230	COG0357	Ribosomal RNA small subunit methyltransferase G
OSSY52_08240	COG0095	Lipoate-protein ligase
OSSY52_08250	COG0019	diaminopimelate decarboxylase activity
OSSY52_08270	COG0840	transmembrane signaling receptor activity
OSSY52_08270	COG3290	protein histidine kinase activity
OSSY52_08280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSSY52_08290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSSY52_08310	COG3852	Histidine kinase
OSSY52_08320	COG2204	response regulator
OSSY52_08330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OSSY52_08350	COG0776	regulation of translation
OSSY52_08360	COG0835	chemotaxis
OSSY52_08410	COG1940	carbohydrate kinase activity
OSSY52_08420	COG0840	transmembrane signaling receptor activity
OSSY52_08500	COG0534	Mate efflux family protein
OSSY52_08510	COG1846	Transcriptional regulator
OSSY52_08540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OSSY52_08550	COG0459	protein refolding
OSSY52_08560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OSSY52_08570	COG0840	transmembrane signaling receptor activity
OSSY52_08590	COG0280	phosphate acetyltransferase
OSSY52_08650	COG0737	Belongs to the 5'-nucleotidase family
OSSY52_08740	COG1653	transport
OSSY52_08750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSSY52_08760	COG0438	transferase activity, transferring glycosyl groups
OSSY52_08870	COG1136	(ABC) transporter
OSSY52_08890	COG1141	Ferredoxin
OSSY52_08900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSSY52_08910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OSSY52_08970	COG0579	oxidoreductase
OSSY52_08980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OSSY52_09010	COG2094	Belongs to the DNA glycosylase MPG family
OSSY52_09020	COG0606	chelatase, subunit chli
OSSY52_09060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSSY52_09070	COG3620	sequence-specific DNA binding
OSSY52_09070	COG0617	tRNA 3'-terminal CCA addition
OSSY52_09070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OSSY52_09090	COG0366	Alpha amylase catalytic
OSSY52_09130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSSY52_09140	COG0504	CTP synthase activity
OSSY52_09190	COG1595	DNA-templated transcription, initiation
OSSY52_09210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OSSY52_09320	COG5002	protein histidine kinase activity
OSSY52_09320	COG3447	MASE1 domain protein
OSSY52_09320	COG5001	Diguanylate cyclase
OSSY52_09350	COG0785	Cytochrome C biogenesis protein
OSSY52_09400	COG0484	heat shock protein binding
OSSY52_09420	COG1164	Oligoendopeptidase f
OSSY52_09430	COG2252	PERMEase
OSSY52_09440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OSSY52_09590	COG1805	sodium ion transport
OSSY52_09600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OSSY52_09620	COG1492	cobalamin metabolic process
OSSY52_09650	COG1121	(ABC) transporter
OSSY52_09660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OSSY52_09670	COG4869	propanediol catabolic process
OSSY52_09680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OSSY52_09690	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OSSY52_09710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OSSY52_09720	COG1418	mRNA catabolic process
OSSY52_09730	COG4106	trans-aconitate 2-methyltransferase activity
OSSY52_09760	COG0495	leucyl-tRNA aminoacylation
OSSY52_09770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OSSY52_09800	COG2431	L-lysine efflux transmembrane transporter activity
OSSY52_09840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OSSY52_09860	COG1027	Aspartate ammonia-lyase
OSSY52_09870	COG0840	transmembrane signaling receptor activity
OSSY52_09880	COG1609	Transcriptional regulator
OSSY52_09890	COG1129	ABC transporter
OSSY52_09940	COG0745	RESPONSE REGULATOR receiver
OSSY52_09950	COG2770	Histidine kinase
OSSY52_09950	COG2205	protein histidine kinase activity
OSSY52_09960	COG1473	amidohydrolase
OSSY52_09970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OSSY52_09990	COG2171	N-acyltransferase activity
OSSY52_10000	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OSSY52_10010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OSSY52_10030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OSSY52_10050	COG1937	Protein conserved in bacteria
OSSY52_10060	COG2217	Heavy metal translocating P-type atpase
OSSY52_10080	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OSSY52_10090	COG3706	GGDEF domain
OSSY52_10110	COG0587	DNA-directed DNA polymerase activity
OSSY52_10120	COG0564	pseudouridine synthase activity
OSSY52_10140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OSSY52_10160	COG0217	transcriptional regulatory protein
OSSY52_10170	COG2208	phosphoserine phosphatase activity
OSSY52_10180	COG2201	protein-glutamate methylesterase activity
OSSY52_10200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSSY52_10230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OSSY52_10250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OSSY52_10260	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OSSY52_10270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OSSY52_10280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OSSY52_10290	COG0358	DNA primase activity
OSSY52_10300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OSSY52_10320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OSSY52_10330	COG0049	tRNA binding
OSSY52_10340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OSSY52_10350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OSSY52_10360	COG0051	transcription antitermination factor activity, RNA binding
OSSY52_10370	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OSSY52_10380	COG0088	Forms part of the polypeptide exit tunnel
OSSY52_10390	COG0089	rRNA binding
OSSY52_10400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OSSY52_10410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OSSY52_10420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OSSY52_10430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OSSY52_10440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OSSY52_10450	COG0255	Belongs to the universal ribosomal protein uL29 family
OSSY52_10460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OSSY52_10470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OSSY52_10480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OSSY52_10490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OSSY52_10500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OSSY52_10510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OSSY52_10520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OSSY52_10530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OSSY52_10540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OSSY52_10550	COG1841	ribosomal large subunit assembly
OSSY52_10560	COG0200	Binds to the 23S rRNA
OSSY52_10570	COG0201	protein transport
OSSY52_10580	COG0563	adenylate kinase activity
OSSY52_10600	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OSSY52_10610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OSSY52_10620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OSSY52_10630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OSSY52_10640	COG0202	RNA polymerase activity
OSSY52_10650	COG0203	ribosomal protein L17
OSSY52_10660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OSSY52_10670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OSSY52_10690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OSSY52_10700	COG1242	4 iron, 4 sulfur cluster binding
OSSY52_10720	COG0402	S-adenosylhomocysteine deaminase activity
OSSY52_10730	COG0235	Class ii aldolase
OSSY52_10790	COG3328	transposase activity
OSSY52_10810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSSY52_10820	COG0052	Belongs to the universal ribosomal protein uS2 family
OSSY52_10830	COG0799	negative regulation of ribosome biogenesis
OSSY52_10840	COG0416	fatty acid biosynthetic process
OSSY52_10850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OSSY52_10890	COG0006	proline dipeptidase activity
OSSY52_10910	COG1307	EDD domain protein, DegV family
OSSY52_10950	COG1863	multisubunit Na H antiporter MnhE subunit
OSSY52_10960	COG2212	antiporter activity
OSSY52_10990	COG2111	Na H antiporter
OSSY52_11000	COG1006	Multisubunit Na H antiporter MnhC subunit
OSSY52_11010	COG0651	ATP synthesis coupled electron transport
OSSY52_11030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OSSY52_11040	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OSSY52_11050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OSSY52_11060	COG0649	NAD binding
OSSY52_11100	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OSSY52_11170	COG0534	Mate efflux family protein
OSSY52_11180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OSSY52_11230	COG0588	phosphoglycerate mutase activity
OSSY52_11240	COG0196	riboflavin kinase activity
OSSY52_11250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OSSY52_11260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OSSY52_11280	COG5002	protein histidine kinase activity
OSSY52_11300	COG2239	Acts as a magnesium transporter
OSSY52_11310	COG2270	Major facilitator Superfamily
OSSY52_11330	COG1677	Flagellar hook-basal body complex protein FliE
OSSY52_11400	COG1744	ABC transporter substrate-binding protein PnrA-like
OSSY52_11410	COG3845	ABC transporter
OSSY52_11420	COG4603	Belongs to the binding-protein-dependent transport system permease family
OSSY52_11430	COG1079	Belongs to the binding-protein-dependent transport system permease family
OSSY52_11440	COG0667	Aldo Keto reductase
OSSY52_11450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OSSY52_11460	COG3956	TIGRFAM MazG family protein
OSSY52_11490	COG2890	protein-(glutamine-N5) methyltransferase activity
OSSY52_11500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OSSY52_11510	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OSSY52_11520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OSSY52_11530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OSSY52_11550	COG0512	Glutamine amidotransferase of anthranilate synthase
OSSY52_11550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OSSY52_11560	COG0134	indole-3-glycerol-phosphate synthase activity
OSSY52_11570	COG0133	tryptophan synthase activity
OSSY52_11580	COG0159	tryptophan synthase activity
OSSY52_11590	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSSY52_11630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSSY52_11650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OSSY52_11660	COG4112	unkown
OSSY52_11670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OSSY52_11680	COG1181	Belongs to the D-alanine--D-alanine ligase family
OSSY52_11690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OSSY52_11700	COG3481	metal-dependent phosphohydrolase, HD sub domain
OSSY52_11710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OSSY52_11730	COG0312	modulator of DNA gyrase
OSSY52_11740	COG0312	modulator of DNA gyrase
OSSY52_11800	COG3328	transposase activity
OSSY52_11820	COG3328	transposase activity
OSSY52_11840	COG3328	transposase activity
OSSY52_11880	COG1132	(ABC) transporter
OSSY52_11890	COG1132	(ABC) transporter
OSSY52_11910	COG5001	Diguanylate cyclase
OSSY52_11910	COG3300	MHYT domain
OSSY52_11970	COG1968	undecaprenyl-diphosphatase activity
OSSY52_11980	COG0671	phosphoesterase, PA-phosphatase related
OSSY52_12000	COG0534	Mate efflux family protein
OSSY52_12030	COG0366	Alpha amylase catalytic
OSSY52_12040	COG0488	(ABC) transporter
OSSY52_12050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSSY52_12060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSSY52_12070	COG1120	ATPase activity
OSSY52_12100	COG0180	Tryptophanyl-tRNA synthetase
OSSY52_12130	COG1187	pseudouridine synthase activity
OSSY52_12150	COG2252	PERMEase
OSSY52_12170	COG1058	Belongs to the CinA family
OSSY52_12170	COG1546	Belongs to the CinA family
OSSY52_12250	COG1528	Iron-storage protein
OSSY52_12280	COG2738	Putative neutral zinc metallopeptidase
OSSY52_12290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OSSY52_12290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OSSY52_12300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OSSY52_12320	COG1162	GTPase activity
OSSY52_12330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OSSY52_12340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OSSY52_12350	COG0004	ammonium transporteR
OSSY52_12370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OSSY52_12420	COG1196	nuclear chromosome segregation
OSSY52_12430	COG1573	uracil-dna glycosylase
OSSY52_12460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OSSY52_12480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OSSY52_12490	COG2255	four-way junction helicase activity
OSSY52_12500	COG0017	Asparaginyl-tRNA synthetase
OSSY52_12520	COG0037	tRNA processing
OSSY52_12530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OSSY52_12550	COG0745	RESPONSE REGULATOR receiver
OSSY52_12560	COG5002	protein histidine kinase activity
OSSY52_12570	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OSSY52_12590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OSSY52_12610	COG0697	spore germination
OSSY52_12630	COG2176	DNA-directed DNA polymerase activity
OSSY52_12640	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OSSY52_12650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OSSY52_12710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OSSY52_12770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OSSY52_12780	COG0629	single-stranded DNA binding
OSSY52_12790	COG0360	Binds together with S18 to 16S ribosomal RNA
OSSY52_12800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OSSY52_12830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OSSY52_12850	COG0511	ligase activity, forming carbon-carbon bonds
OSSY52_12880	COG0346	lactoylglutathione lyase activity
OSSY52_12900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OSSY52_12900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OSSY52_12910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OSSY52_12910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OSSY52_12990	COG0411	ABC transporter
OSSY52_13010	COG0559	Belongs to the binding-protein-dependent transport system permease family
OSSY52_13030	COG0157	Belongs to the NadC ModD family
OSSY52_13040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OSSY52_13050	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
OSSY52_13060	COG1592	Rubrerythrin
OSSY52_13070	COG0443	Heat shock 70 kDa protein
OSSY52_13100	COG0445	tRNA wobble uridine modification
OSSY52_13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSSY52_13300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OSSY52_13300	COG0731	radical SAM domain protein
OSSY52_13340	COG1067	ATP-dependent peptidase activity
OSSY52_13350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OSSY52_13360	COG4191	Histidine kinase
OSSY52_13360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSSY52_13370	COG3437	response regulator, receiver
OSSY52_13370	COG0784	Response regulator, receiver
OSSY52_13380	COG3437	response regulator, receiver
OSSY52_13380	COG0784	Response regulator, receiver
OSSY52_13420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OSSY52_13430	COG0154	amidase activity
OSSY52_13440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OSSY52_13500	COG4989	oxidoreductase activity
OSSY52_13510	COG1671	Belongs to the UPF0178 family
OSSY52_13530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OSSY52_13540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OSSY52_13550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OSSY52_13560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OSSY52_13570	COG0047	phosphoribosylformylglycinamidine synthase activity
OSSY52_13600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OSSY52_13620	COG0277	FAD linked oxidase domain protein
OSSY52_13630	COG1070	Carbohydrate kinase
OSSY52_13670	COG2188	Transcriptional regulator
OSSY52_13710	COG3852	Histidine kinase
OSSY52_13760	COG3328	transposase activity
OSSY52_13770	COG3328	transposase activity
OSSY52_13820	COG0151	Belongs to the GarS family
OSSY52_13870	COG0426	domain, Protein
OSSY52_13890	COG2033	superoxide reductase activity
OSSY52_13900	COG1592	Rubrerythrin
OSSY52_13910	COG0300	oxidoreductase activity
OSSY52_13920	COG1653	transport
OSSY52_13930	COG1175	transmembrane transport
OSSY52_13950	COG0419	ATPase involved in DNA repair
OSSY52_13960	COG0420	3'-5' exonuclease activity
OSSY52_13970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OSSY52_13980	COG0402	S-adenosylhomocysteine deaminase activity
OSSY52_14030	COG0826	peptidase U32
OSSY52_14070	COG0719	Fe-S assembly protein
OSSY52_14080	COG1122	ATPase activity
OSSY52_14090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OSSY52_14100	COG0772	Belongs to the SEDS family
OSSY52_14140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OSSY52_14140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OSSY52_14150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OSSY52_14160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OSSY52_14180	COG1766	The M ring may be actively involved in energy transduction
OSSY52_14190	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSSY52_14210	COG1157	protein secretion by the type III secretion system
OSSY52_14230	COG0395	ABC-type sugar transport system, permease component
OSSY52_14250	COG2136	Putative SAM-dependent methyltransferase
OSSY52_14250	COG2521	methyltransferase
OSSY52_14260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OSSY52_14270	COG1923	regulation of RNA biosynthetic process
OSSY52_14290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OSSY52_14310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OSSY52_14320	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OSSY52_14340	COG1827	regulation of RNA biosynthetic process
OSSY52_14350	COG2271	Major facilitator Superfamily
OSSY52_14360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OSSY52_14370	COG2198	Histidine kinase
OSSY52_14370	COG0643	Histidine kinase
OSSY52_14380	COG2201	protein-glutamate methylesterase activity
OSSY52_14400	COG1338	Plays a role in the flagellum-specific transport system
OSSY52_14410	COG1987	bacterial-type flagellum assembly
OSSY52_14420	COG1684	flagellar biosynthetic protein fliR
OSSY52_14430	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OSSY52_14440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OSSY52_14450	COG1419	protein localization to endoplasmic reticulum
OSSY52_14490	COG1776	CheC inhibitor of MCP methylation
OSSY52_14500	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OSSY52_14510	COG1191	sigma factor activity
OSSY52_14550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OSSY52_14560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OSSY52_14600	COG2204	response regulator
OSSY52_14610	COG1739	Uncharacterized protein family UPF0029
OSSY52_14620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OSSY52_14650	COG0300	oxidoreductase activity
OSSY52_14670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSSY52_14680	COG1496	oxidoreductase activity
OSSY52_14690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSSY52_14700	COG2183	response to ionizing radiation
OSSY52_14710	COG0519	Catalyzes the synthesis of GMP from XMP
OSSY52_14710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OSSY52_14760	COG0402	S-adenosylhomocysteine deaminase activity
OSSY52_14790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSSY52_14830	COG1268	BioY protein
OSSY52_14850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OSSY52_14870	COG0613	PHP domain protein
OSSY52_14880	COG0584	glycerophosphoryl diester phosphodiesterase
OSSY52_14910	COG0305	Participates in initiation and elongation during chromosome replication
OSSY52_14920	COG0557	exoribonuclease II activity
OSSY52_14930	COG0359	binds to the 23S rRNA
OSSY52_14940	COG1234	tRNA 3'-trailer cleavage
OSSY52_15000	COG0517	IMP dehydrogenase activity
OSSY52_15000	COG0516	GMP reductase activity
OSSY52_15010	COG1323	Belongs to the UPF0348 family
OSSY52_15020	COG0012	GTP binding
OSSY52_15050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OSSY52_15060	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OSSY52_15070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OSSY52_15090	COG0205	6-phosphofructokinase activity
OSSY52_15100	COG0469	pyruvate kinase activity
OSSY52_15110	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OSSY52_15150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OSSY52_15170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OSSY52_15180	COG1490	D-aminoacyl-tRNA deacylase activity
OSSY52_15210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OSSY52_15250	COG2199	diguanylate cyclase activity
OSSY52_15250	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OSSY52_15270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OSSY52_15280	COG0750	zinc metalloprotease
OSSY52_15290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OSSY52_15310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OSSY52_15320	COG1774	PSP1 C-terminal conserved region
OSSY52_15340	COG0571	ribonuclease III activity
OSSY52_15370	COG3829	transcription factor binding
OSSY52_15370	COG3290	protein histidine kinase activity
OSSY52_15410	COG0174	glutamine synthetase
OSSY52_15420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OSSY52_15430	COG2342	PFAM TM1410 hypothetical-related protein
OSSY52_15440	COG0009	L-threonylcarbamoyladenylate synthase
OSSY52_15450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OSSY52_15460	COG1032	radical SAM domain protein
OSSY52_15500	COG3842	ATPase activity
OSSY52_15520	COG0205	6-phosphofructokinase activity
OSSY52_15530	COG2027	D-alanyl-D-alanine carboxypeptidase
OSSY52_15540	COG0116	Belongs to the methyltransferase superfamily
OSSY52_15560	COG3437	response regulator, receiver
OSSY52_15580	COG2022	thiamine diphosphate biosynthetic process
OSSY52_15590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OSSY52_15600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OSSY52_15610	COG1992	Thiamine-phosphate synthase
OSSY52_15610	COG0351	phosphomethylpyrimidine kinase
OSSY52_15690	COG1918	ferrous iron import across plasma membrane
OSSY52_15690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OSSY52_15770	COG0582	viral genome integration into host DNA
OSSY52_15790	COG2313	pseudouridylate synthase activity
OSSY52_15800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSSY52_15810	COG0583	DNA-binding transcription factor activity
OSSY52_15820	COG4716	Myosin-crossreactive antigen
OSSY52_15870	COG0626	cystathionine gamma-synthase activity
OSSY52_15880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OSSY52_15900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OSSY52_15960	COG0425	Belongs to the sulfur carrier protein TusA family
OSSY52_15970	COG2391	methyltransferase activity
OSSY52_16020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OSSY52_16030	COG0509	glycine decarboxylation via glycine cleavage system
OSSY52_16040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OSSY52_16040	COG0167	dihydroorotate dehydrogenase activity
OSSY52_16060	COG0640	Transcriptional regulator
OSSY52_16110	COG1131	(ABC) transporter
OSSY52_16150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OSSY52_16170	COG3328	transposase activity
OSSY52_16220	COG0493	'glutamate synthase
OSSY52_16220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OSSY52_16230	COG1362	aminopeptidase activity
OSSY52_16240	COG1363	Peptidase, m42
OSSY52_16250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OSSY52_16260	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OSSY52_16330	COG0406	alpha-ribazole phosphatase activity
OSSY52_16350	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OSSY52_16370	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
OSSY52_16400	COG0747	negative chemotaxis
OSSY52_16410	COG0601	transmembrane transport
OSSY52_16420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OSSY52_16440	COG0444	Belongs to the ABC transporter superfamily
OSSY52_16450	COG4608	Belongs to the ABC transporter superfamily
OSSY52_16480	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OSSY52_16490	COG0649	NAD binding
OSSY52_16500	COG0651	ATP synthesis coupled electron transport
OSSY52_16520	COG0650	Formate hydrogenlyase subunit 4
OSSY52_16530	COG0651	ATP synthesis coupled electron transport
OSSY52_16550	COG1011	Hydrolase
OSSY52_16560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OSSY52_16570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OSSY52_16570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OSSY52_16580	COG0307	riboflavin synthase, alpha
OSSY52_16590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OSSY52_16590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OSSY52_16600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OSSY52_16610	COG1993	acr, cog1993
OSSY52_16630	COG2207	Transcriptional regulator
OSSY52_16630	COG3708	Transcriptional regulator
OSSY52_16650	COG3328	transposase activity
OSSY52_16670	COG0312	modulator of DNA gyrase
OSSY52_16690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSSY52_16700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OSSY52_16710	COG1028	Short-chain dehydrogenase reductase Sdr
OSSY52_16720	COG0427	acetyl-CoA hydrolase
OSSY52_16730	COG0183	Belongs to the thiolase family
OSSY52_16780	COG2267	carboxylic ester hydrolase activity
OSSY52_16790	COG1309	transcriptional regulator
OSSY52_16830	COG0668	transmembrane transport
OSSY52_16880	COG1132	(ABC) transporter
OSSY52_16910	COG1846	Transcriptional regulator
OSSY52_16920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OSSY52_16990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OSSY52_17040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OSSY52_17050	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OSSY52_17060	COG0747	negative chemotaxis
OSSY52_17080	COG2197	response regulator
OSSY52_17090	COG4585	Histidine kinase
OSSY52_17100	COG0326	Molecular chaperone. Has ATPase activity
OSSY52_17120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OSSY52_17140	COG1408	metallophosphoesterase
OSSY52_17180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OSSY52_17200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OSSY52_17200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OSSY52_17210	COG0251	oxidation-reduction process
OSSY52_17230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OSSY52_17260	COG1254	Belongs to the acylphosphatase family
OSSY52_17290	COG0573	inorganic phosphate transmembrane transporter activity
OSSY52_17290	COG0581	inorganic phosphate transmembrane transporter activity
OSSY52_17310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OSSY52_17320	COG0704	Plays a role in the regulation of phosphate uptake
OSSY52_17330	COG0745	RESPONSE REGULATOR receiver
OSSY52_17340	COG5002	protein histidine kinase activity
OSSY52_17370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OSSY52_17380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OSSY52_17390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OSSY52_17400	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OSSY52_17410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OSSY52_17430	COG2203	Gaf domain
OSSY52_17430	COG2199	diguanylate cyclase activity
OSSY52_17440	COG0306	phosphate transporter
OSSY52_17460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OSSY52_17480	COG0012	GTP binding
OSSY52_17490	COG0802	atpase or kinase
OSSY52_17530	COG1797	cobyrinic acid a,c-diamide synthase activity
OSSY52_17550	COG1120	ATPase activity
OSSY52_17560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSSY52_17670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OSSY52_17680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OSSY52_17720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OSSY52_17720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OSSY52_17760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OSSY52_17770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OSSY52_17780	COG2081	HI0933 family
OSSY52_17860	COG1136	(ABC) transporter
OSSY52_17870	COG0105	UTP biosynthetic process
OSSY52_17880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OSSY52_17890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OSSY52_17900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OSSY52_17940	COG4656	Part of a membrane complex involved in electron transport
OSSY52_17950	COG4658	electron transport chain
OSSY52_17970	COG4660	Part of a membrane complex involved in electron transport
OSSY52_17980	COG4657	Part of a membrane complex involved in electron transport
OSSY52_18000	COG3706	GGDEF domain
OSSY52_18010	COG1073	alpha beta
OSSY52_18020	COG0747	negative chemotaxis
OSSY52_18030	COG0601	transmembrane transport
OSSY52_18050	COG0444	Belongs to the ABC transporter superfamily
OSSY52_18060	COG4608	Belongs to the ABC transporter superfamily
OSSY52_18070	COG2723	6-phospho-beta-galactosidase activity
OSSY52_18130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OSSY52_18150	COG2188	Transcriptional regulator
OSSY52_18190	COG0395	ABC-type sugar transport system, permease component
OSSY52_18200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OSSY52_18200	COG3291	Pkd domain containing protein
OSSY52_18210	COG2235	arginine
OSSY52_18220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OSSY52_18230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSSY52_18240	COG1288	antiporter activity
OSSY52_18270	COG2176	DNA-directed DNA polymerase activity
OSSY52_18290	COG0617	tRNA 3'-terminal CCA addition
OSSY52_18290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OSSY52_18290	COG0517	IMP dehydrogenase activity
OSSY52_18310	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
OSSY52_18350	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OSSY52_18360	COG1555	photosystem II stabilization
OSSY52_18360	COG1596	polysaccharide export
OSSY52_18380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OSSY52_18400	COG0698	ribose 5-phosphate isomerase
OSSY52_18420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OSSY52_18430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OSSY52_18440	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSSY52_18440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSSY52_18450	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
OSSY52_18490	COG0584	glycerophosphoryl diester phosphodiesterase
OSSY52_18510	COG1979	alcohol dehydrogenase
OSSY52_18530	COG0793	Belongs to the peptidase S41A family
OSSY52_18580	COG0512	Glutamine amidotransferase of anthranilate synthase
OSSY52_18600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OSSY52_18610	COG0302	gtp cyclohydrolase
OSSY52_18620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OSSY52_18630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OSSY52_18640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OSSY52_18780	COG4245	von Willebrand factor, type A
OSSY52_18830	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OSSY52_19020	COG0085	RNA polymerase activity
OSSY52_19190	COG1454	alcohol dehydrogenase
OSSY52_19210	COG3234	Protein of unknown function (DUF1175)
OSSY52_19220	COG0018	arginyl-trna synthetase
OSSY52_19230	COG4214	carbohydrate transport
OSSY52_19250	COG4213	ABC transporter substrate-binding protein
OSSY52_19260	COG4191	Histidine kinase
OSSY52_19270	COG2204	response regulator
OSSY52_19300	COG3328	transposase activity
OSSY52_19330	COG1131	(ABC) transporter
OSSY52_19380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OSSY52_19390	COG3328	transposase activity
OSSY52_19470	COG1131	(ABC) transporter
OSSY52_19480	COG0535	radical SAM domain protein
OSSY52_19490	COG0535	radical SAM domain protein
OSSY52_19550	COG1506	peptidase
OSSY52_19550	COG4946	Tricorn protease homolog
OSSY52_19550	COG0823	Involved in the tonB-independent uptake of proteins
OSSY52_19580	COG0745	RESPONSE REGULATOR receiver
OSSY52_19590	COG5002	protein histidine kinase activity
OSSY52_19620	COG0148	phosphopyruvate hydratase activity
OSSY52_19630	COG0528	UMP kinase activity
OSSY52_19640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OSSY52_19650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OSSY52_19660	COG0482	sulfurtransferase activity
OSSY52_19670	COG1959	2 iron, 2 sulfur cluster binding
OSSY52_19680	COG3584	3D domain protein
OSSY52_19700	COG0552	protein localization to endoplasmic reticulum
OSSY52_19760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OSSY52_19770	COG0544	peptidyl-prolyl cis-trans isomerase activity
OSSY52_19800	COG0149	triose-phosphate isomerase activity
OSSY52_19800	COG0126	phosphoglycerate kinase activity
OSSY52_19820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OSSY52_19860	COG0497	DNA recombination
OSSY52_19880	COG3706	GGDEF domain
OSSY52_19890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSSY52_19920	COG1610	YqeY-like protein
OSSY52_19930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OSSY52_19940	COG0736	holo-[acyl-carrier-protein] synthase activity
OSSY52_19960	COG1193	negative regulation of DNA recombination
OSSY52_19980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OSSY52_19990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OSSY52_20010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OSSY52_20020	COG0740	serine-type endopeptidase activity
OSSY52_20040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OSSY52_20050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OSSY52_20060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OSSY52_20070	COG1012	belongs to the aldehyde dehydrogenase family
OSSY52_20100	COG0768	penicillin binding
OSSY52_20130	COG1077	Cell shape determining protein MreB Mrl
OSSY52_20140	COG1396	sequence-specific DNA binding
OSSY52_20140	COG1917	Cupin 2, conserved barrel domain protein
OSSY52_20150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OSSY52_20160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OSSY52_20190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OSSY52_20190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OSSY52_20200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSSY52_20210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OSSY52_20230	COG0438	transferase activity, transferring glycosyl groups
OSSY52_20270	COG1702	phosphate starvation-inducible protein PhoH
OSSY52_20280	COG1480	7TM receptor with intracellular HD hydrolase
OSSY52_20290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OSSY52_20320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OSSY52_20350	COG1045	serine acetyltransferase
OSSY52_20400	COG2827	Endonuclease containing a URI domain
OSSY52_20420	COG2205	protein histidine kinase activity
OSSY52_20420	COG0784	Response regulator, receiver
OSSY52_20430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OSSY52_20440	COG0275	rRNA processing
OSSY52_20460	COG0768	penicillin binding
OSSY52_20490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OSSY52_20500	COG3586	endonuclease activity
OSSY52_20540	COG5002	protein histidine kinase activity
OSSY52_20550	COG1032	radical SAM domain protein
OSSY52_20590	COG0442	prolyl-tRNA aminoacylation
OSSY52_20600	COG1132	(ABC) transporter
OSSY52_20610	COG1132	(ABC) transporter
OSSY52_20640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OSSY52_20690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OSSY52_20700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OSSY52_20730	COG0187	DNA topoisomerase II activity
OSSY52_20750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OSSY52_20760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSSY52_20770	COG0517	IMP dehydrogenase activity
OSSY52_20770	COG0516	GMP reductase activity
OSSY52_20780	COG1105	Belongs to the carbohydrate kinase PfkB family
OSSY52_20800	COG1309	transcriptional regulator
OSSY52_20820	COG0301	tRNA thio-modification
OSSY52_20870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OSSY52_20940	COG1307	EDD domain protein, DegV family
OSSY52_20950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OSSY52_20960	COG0742	ribosomal rna small subunit methyltransferase
OSSY52_20970	COG0640	Transcriptional regulator
OSSY52_20980	COG2217	Heavy metal translocating P-type atpase
OSSY52_20990	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSSY52_21000	COG0739	heme binding
OSSY52_21010	COG2201	protein-glutamate methylesterase activity
OSSY52_21020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OSSY52_21040	COG1013	pyruvate-flavodoxin oxidoreductase activity
OSSY52_21050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OSSY52_21080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSSY52_21090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OSSY52_21160	COG2373	Large extracellular alpha-helical protein
OSSY52_21170	COG0514	ATP-dependent DNA helicase (RecQ)
OSSY52_21190	COG1051	belongs to the nudix hydrolase family
OSSY52_21200	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OSSY52_21250	COG2986	histidine ammonia-lyase
OSSY52_21270	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OSSY52_21350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OSSY52_21370	COG0835	chemotaxis
OSSY52_21410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OSSY52_21410	COG2199	diguanylate cyclase activity
OSSY52_21450	COG0330	HflC and HflK could
OSSY52_21460	COG0330	HflC and HflK could
OSSY52_21470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OSSY52_21470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OSSY52_21480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OSSY52_21490	COG0444	Belongs to the ABC transporter superfamily
OSSY52_21500	COG4608	Belongs to the ABC transporter superfamily
OSSY52_21520	COG0601	transmembrane transport
OSSY52_21530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OSSY52_21540	COG0840	transmembrane signaling receptor activity
OSSY52_21550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OSSY52_21560	COG0543	2 iron, 2 sulfur cluster binding
OSSY52_21570	COG0167	dihydroorotate dehydrogenase activity
OSSY52_21580	COG0284	orotidine-5'-phosphate decarboxylase activity
OSSY52_21590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OSSY52_21600	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OSSY52_21640	COG1362	aminopeptidase activity
OSSY52_21680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OSSY52_21690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OSSY52_21700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OSSY52_21710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OSSY52_21730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OSSY52_21740	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OSSY52_21750	COG0356	it plays a direct role in the translocation of protons across the membrane
OSSY52_21810	COG2078	PFAM AMMECR1 domain protein
OSSY52_21830	COG1477	protein flavinylation
OSSY52_21860	COG0424	maF-like protein
OSSY52_21870	COG2003	Belongs to the UPF0758 family
OSSY52_21890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OSSY52_21900	COG4143	(ABC) transporter
OSSY52_22000	COG1528	Iron-storage protein
OSSY52_22010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OSSY52_22020	COG0450	alkyl hydroperoxide reductase
OSSY52_22050	COG1132	(ABC) transporter
OSSY52_22070	COG1007	ATP synthesis coupled electron transport
OSSY52_22150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OSSY52_22170	COG2199	diguanylate cyclase activity
OSSY52_22170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OSSY52_22180	COG3437	response regulator, receiver
OSSY52_22190	COG0612	Peptidase, M16
OSSY52_22200	COG1185	polyribonucleotide nucleotidyltransferase activity
OSSY52_22210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OSSY52_22260	COG3706	GGDEF domain
OSSY52_22290	COG1307	EDD domain protein, DegV family
OSSY52_22300	COG1924	4 iron, 4 sulfur cluster binding
OSSY52_22310	COG2226	methyltransferase
OSSY52_22320	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OSSY52_22340	COG0436	Aminotransferase
OSSY52_22360	COG2723	6-phospho-beta-galactosidase activity
OSSY52_22370	COG4085	toxin activity
OSSY52_22370	COG1525	nuclease
OSSY52_22370	COG0737	Belongs to the 5'-nucleotidase family
OSSY52_22390	COG1760	l-serine dehydratase
OSSY52_22400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OSSY52_22400	COG1215	transferase activity, transferring glycosyl groups
OSSY52_22410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OSSY52_22430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OSSY52_22440	COG0562	UDP-galactopyranose mutase
OSSY52_22450	COG1215	transferase activity, transferring glycosyl groups
OSSY52_22470	COG0438	transferase activity, transferring glycosyl groups
OSSY52_22480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OSSY52_22520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OSSY52_22550	COG1523	belongs to the glycosyl hydrolase 13 family
OSSY52_22560	COG0481	GTPase activity
OSSY52_22590	COG0556	nucleotide-excision repair
OSSY52_22600	COG1011	Hydrolase
OSSY52_22610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OSSY52_22620	COG0085	RNA polymerase activity
OSSY52_22630	COG0222	ribosome binding
OSSY52_22640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OSSY52_22650	COG0081	regulation of translation
OSSY52_22660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OSSY52_22670	COG0250	Participates in transcription elongation, termination and antitermination
OSSY52_22680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OSSY52_22690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OSSY52_22710	COG0542	response to heat
OSSY52_22720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OSSY52_22730	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OSSY52_22740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OSSY52_22760	COG1187	pseudouridine synthase activity
OSSY52_22770	COG1846	Transcriptional regulator
OSSY52_22800	COG1752	Esterase of the alpha-beta hydrolase superfamily
OSSY52_22830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OSSY52_22840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OSSY52_22880	COG1749	Flagellar hook protein flgE
OSSY52_22930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSSY52_22940	COG1776	CheC inhibitor of MCP methylation
OSSY52_22940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSSY52_22970	COG1132	(ABC) transporter
OSSY52_22980	COG1132	(ABC) transporter