locus-tag	class	description
KS242_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KS242_00010	COG0592	DNA-directed DNA polymerase activity
KS242_00015	COG2501	S4 domain
KS242_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KS242_00030	COG0187	DNA topoisomerase II activity
KS242_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KS242_00040	COG3437	response regulator, receiver
KS242_00050	COG0516	GMP reductase activity
KS242_00050	COG0517	IMP dehydrogenase activity
KS242_00055	COG2358	TRAP transporter, solute receptor (TAXI family
KS242_00070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KS242_00080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KS242_00090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KS242_00095	COG1428	Deoxynucleoside kinase
KS242_00100	COG1428	Deoxynucleoside kinase
KS242_00110	COG4974	Belongs to the 'phage' integrase family
KS242_00120	COG0827	DNA restriction-modification system
KS242_00205	COG0697	spore germination
KS242_00220	COG1012	belongs to the aldehyde dehydrogenase family
KS242_00225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS242_00230	COG0693	protein deglycase activity
KS242_00240	COG1388	LysM domain
KS242_00240	COG3858	chitin binding
KS242_00245	COG1335	isochorismatase
KS242_00250	COG0590	tRNA wobble adenosine to inosine editing
KS242_00260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KS242_00265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KS242_00270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KS242_00335	COG1982	Orn Lys Arg decarboxylase major
KS242_00340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KS242_00345	COG3870	Protein conserved in bacteria
KS242_00350	COG1728	Protein conserved in bacteria
KS242_00355	COG0470	DNA polymerase III
KS242_00360	COG1774	PSP1 C-terminal conserved region
KS242_00365	COG4467	Involved in initiation control of chromosome replication
KS242_00375	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KS242_00380	COG2827	Endonuclease containing a URI domain
KS242_00385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KS242_00390	COG2002	toxin-antitoxin pair type II binding
KS242_00400	COG0084	hydrolase, TatD family'
KS242_00410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KS242_00420	COG4466	Protein conserved in bacteria
KS242_00430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KS242_00435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KS242_00445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KS242_00455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KS242_00460	COG1595	DNA-templated transcription, initiation
KS242_00480	COG1131	(ABC) transporter
KS242_00485	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS242_00490	COG0193	aminoacyl-tRNA hydrolase activity
KS242_00500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KS242_00505	COG2002	toxin-antitoxin pair type II binding
KS242_00510	COG1917	Cupin 2, conserved barrel domain protein
KS242_00510	COG4977	sequence-specific DNA binding
KS242_00520	COG2244	polysaccharide biosynthetic process
KS242_00525	COG3956	TIGRFAM MazG family protein
KS242_00530	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KS242_00550	COG1098	S1 RNA binding domain
KS242_00565	COG0406	alpha-ribazole phosphatase activity
KS242_00580	COG2814	Major facilitator Superfamily
KS242_00590	COG2208	phosphoserine phosphatase activity
KS242_00595	COG2304	oxidoreductase activity
KS242_00600	COG0515	serine threonine protein kinase
KS242_00605	COG0037	tRNA processing
KS242_00610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KS242_00615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KS242_00620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KS242_00625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS242_00630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KS242_00635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KS242_00640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KS242_00645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KS242_00650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KS242_00730	COG1285	pathogenesis
KS242_00740	COG3880	PFAM UvrB UvrC protein
KS242_00745	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KS242_00750	COG0542	response to heat
KS242_00755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KS242_00760	COG4956	integral membrane protein (PIN domain superfamily)
KS242_00765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KS242_00770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KS242_00775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KS242_00780	COG1045	serine acetyltransferase
KS242_00785	COG0215	cysteine-tRNA ligase activity
KS242_00795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KS242_00800	COG3688	RNA-binding protein containing a PIN domain
KS242_00810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KS242_00815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KS242_00820	COG0250	Participates in transcription elongation, termination and antitermination
KS242_00825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KS242_00830	COG0081	regulation of translation
KS242_00835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KS242_00840	COG0222	ribosome binding
KS242_00845	COG2813	Specifically methylates the guanine in position
KS242_00850	COG0085	RNA polymerase activity
KS242_00855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KS242_00860	COG1358	cellular component organization or biogenesis
KS242_00865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KS242_00870	COG0049	tRNA binding
KS242_00875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KS242_00880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KS242_00890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KS242_00895	COG0088	Forms part of the polypeptide exit tunnel
KS242_00900	COG0089	rRNA binding
KS242_00905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KS242_00910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KS242_00915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KS242_00920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KS242_00925	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KS242_00930	COG0255	Belongs to the universal ribosomal protein uL29 family
KS242_00935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KS242_00940	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KS242_00945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KS242_00950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KS242_00955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KS242_00960	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KS242_00965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KS242_00970	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KS242_00975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KS242_00980	COG1841	ribosomal large subunit assembly
KS242_00985	COG0200	Binds to the 23S rRNA
KS242_00990	COG0201	protein transport
KS242_00995	COG0563	adenylate kinase activity
KS242_01005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KS242_01010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KS242_01015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KS242_01025	COG0202	RNA polymerase activity
KS242_01030	COG0203	ribosomal protein L17
KS242_01035	COG1122	ATPase activity
KS242_01040	COG1122	ATPase activity
KS242_01045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KS242_01050	COG0101	tRNA pseudouridine synthase activity
KS242_01055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KS242_01060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KS242_01075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS242_01080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS242_01080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS242_01080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_01090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KS242_01105	COG0584	glycerophosphoryl diester phosphodiesterase
KS242_01135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS242_01155	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS242_01160	COG0489	protein tyrosine kinase activity
KS242_01170	COG0726	polysaccharide deacetylase
KS242_01215	COG0582	viral genome integration into host DNA
KS242_01270	COG0446	pyridine nucleotide-disulphide oxidoreductase
KS242_01275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KS242_01280	COG0640	Transcriptional regulator
KS242_01295	COG0217	transcriptional regulatory protein
KS242_01300	COG4412	M6 family metalloprotease domain protein
KS242_01300	COG1404	Belongs to the peptidase S8 family
KS242_01305	COG1012	belongs to the aldehyde dehydrogenase family
KS242_01365	COG0477	Major facilitator Superfamily
KS242_01380	COG1595	DNA-templated transcription, initiation
KS242_01385	COG5662	AntiSigma factor
KS242_01390	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KS242_01395	COG4856	YbbR-like protein
KS242_01400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KS242_01405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KS242_01445	COG1136	(ABC) transporter
KS242_01450	COG0577	efflux transmembrane transporter activity
KS242_01470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KS242_01485	COG4585	Histidine kinase
KS242_01490	COG2197	response regulator
KS242_01495	COG1131	(ABC) transporter
KS242_01520	COG3507	Belongs to the glycosyl hydrolase 43 family
KS242_01525	COG1082	Xylose isomerase domain protein TIM barrel
KS242_01600	COG2203	Gaf domain
KS242_01600	COG3706	GGDEF domain
KS242_01600	COG5001	Diguanylate cyclase
KS242_01600	COG4251	negative regulation of phosphorylation
KS242_01610	COG2814	Major facilitator Superfamily
KS242_01615	COG0640	Transcriptional regulator
KS242_01620	COG2814	Major facilitator Superfamily
KS242_01640	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_01650	COG0352	thiamine-phosphate diphosphorylase activity
KS242_01660	COG2104	thiamine diphosphate biosynthetic process
KS242_01665	COG2022	thiamine diphosphate biosynthetic process
KS242_01670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KS242_01685	COG0456	acetyltransferase
KS242_01690	COG0589	response to stress
KS242_01705	COG1131	(ABC) transporter
KS242_01720	COG0656	L-ascorbic acid biosynthetic process
KS242_01725	COG0656	L-ascorbic acid biosynthetic process
KS242_01745	COG0789	Transcriptional regulator
KS242_01760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KS242_01775	COG2112	serine threonine protein kinase
KS242_01790	COG1253	flavin adenine dinucleotide binding
KS242_01795	COG0662	Cupin 2, conserved barrel domain protein
KS242_01795	COG2207	Transcriptional regulator
KS242_01800	COG0673	inositol 2-dehydrogenase activity
KS242_01830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KS242_01855	COG1252	NADH dehydrogenase
KS242_01860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KS242_01875	COG1309	transcriptional regulator
KS242_01880	COG0477	Major facilitator Superfamily
KS242_01885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS242_01905	COG3226	Transcriptional regulator
KS242_01910	COG1012	belongs to the aldehyde dehydrogenase family
KS242_01915	COG0281	malic enzyme
KS242_01925	COG4221	oxidoreductase activity
KS242_01935	COG1012	belongs to the aldehyde dehydrogenase family
KS242_01940	COG0702	epimerase
KS242_01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS242_01955	COG0778	Nitroreductase
KS242_01975	COG5577	PFAM Coat F domain
KS242_01980	COG1063	alcohol dehydrogenase
KS242_01995	COG4894	glucomannan catabolic process
KS242_02000	COG0702	epimerase
KS242_02005	COG1289	transmembrane transporter activity
KS242_02010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KS242_02015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KS242_02020	COG1346	cytolysis
KS242_02025	COG1380	Effector of murein hydrolase LrgA
KS242_02030	COG0583	DNA-binding transcription factor activity
KS242_02040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS242_02045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KS242_02050	COG1522	sequence-specific DNA binding
KS242_02055	COG0436	Aminotransferase
KS242_02065	COG1902	pentaerythritol trinitrate reductase activity
KS242_02075	COG3711	transcriptional antiterminator
KS242_02080	COG2190	(PTS) system
KS242_02080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS242_02080	COG1263	PTS System
KS242_02095	COG1725	Transcriptional regulator
KS242_02100	COG1131	(ABC) transporter
KS242_02120	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_02125	COG0596	Alpha beta hydrolase
KS242_02140	COG0840	transmembrane signaling receptor activity
KS242_02145	COG0840	transmembrane signaling receptor activity
KS242_02150	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_02160	COG1876	peptidase activity
KS242_02165	COG1418	mRNA catabolic process
KS242_02175	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_02190	COG1970	mechanosensitive ion channel activity
KS242_02200	COG2211	Major facilitator Superfamily
KS242_02210	COG1227	inorganic diphosphatase activity
KS242_02215	COG0656	L-ascorbic acid biosynthetic process
KS242_02220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KS242_02225	COG1442	glycosyl transferase family 8
KS242_02230	COG1827	regulation of RNA biosynthetic process
KS242_02235	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_02240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KS242_02250	COG3279	Response regulator of the LytR AlgR family
KS242_02265	COG2814	Major facilitator Superfamily
KS242_02270	COG0561	phosphatase activity
KS242_02275	COG1132	(ABC) transporter
KS242_02290	COG0679	Auxin Efflux Carrier
KS242_02295	COG0281	malic enzyme
KS242_02310	COG1733	regulation of RNA biosynthetic process
KS242_02315	COG0590	tRNA wobble adenosine to inosine editing
KS242_02325	COG0492	ferredoxin-NADP+ reductase activity
KS242_02330	COG0561	phosphatase activity
KS242_02335	COG0463	Glycosyl transferase, family 2
KS242_02345	COG4485	Bacterial membrane protein, YfhO
KS242_02350	COG0741	lytic transglycosylase activity
KS242_02355	COG1737	Transcriptional regulator
KS242_02360	COG1072	(Pantothenic acid kinase))
KS242_02365	COG1263	PTS System
KS242_02365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS242_02370	COG0366	Alpha amylase catalytic
KS242_02375	COG2188	Transcriptional regulator
KS242_02380	COG1247	-acetyltransferase
KS242_02395	COG2814	Major facilitator Superfamily
KS242_02420	COG3871	stress protein (general stress protein 26)
KS242_02425	COG1834	amidinotransferase
KS242_02430	COG1979	alcohol dehydrogenase
KS242_02435	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_02450	COG1725	Transcriptional regulator
KS242_02455	COG1131	(ABC) transporter
KS242_02460	COG1131	(ABC) transporter
KS242_02465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS242_02470	COG1764	response to oxidative stress
KS242_02495	COG1131	(ABC) transporter
KS242_02500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS242_02525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KS242_02535	COG0716	FMN binding
KS242_02540	COG0432	Pfam Uncharacterised protein family UPF0047
KS242_02545	COG2200	EAL domain
KS242_02550	COG0840	transmembrane signaling receptor activity
KS242_02560	COG1533	DNA photolyase activity
KS242_02565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KS242_02575	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KS242_02585	COG0352	thiamine-phosphate diphosphorylase activity
KS242_02590	COG3012	SEC-C Motif Domain Protein
KS242_02625	COG0463	Glycosyl transferase, family 2
KS242_02625	COG0457	Tetratricopeptide repeat
KS242_02635	COG2814	Major facilitator Superfamily
KS242_02640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KS242_02645	COG0371	Dehydrogenase
KS242_02650	COG0436	Aminotransferase
KS242_02655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS242_02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KS242_02670	COG1181	Belongs to the D-alanine--D-alanine ligase family
KS242_02675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KS242_02680	COG0720	synthase
KS242_02685	COG0602	queuosine metabolic process
KS242_02690	COG0137	argininosuccinate synthase activity
KS242_02695	COG0165	Argininosuccinate lyase
KS242_02700	COG0505	Belongs to the CarA family
KS242_02705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KS242_02710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KS242_02730	COG0307	riboflavin synthase, alpha
KS242_02735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS242_02735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS242_02770	COG0300	oxidoreductase activity
KS242_02780	COG0386	Belongs to the glutathione peroxidase family
KS242_02790	COG1054	Belongs to the UPF0176 family
KS242_02805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KS242_02815	COG2084	Dehydrogenase
KS242_02820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS242_02830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS242_02840	COG0463	Glycosyl transferase, family 2
KS242_02845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS242_02850	COG0745	RESPONSE REGULATOR receiver
KS242_02855	COG5002	protein histidine kinase activity
KS242_02860	COG1217	gtp-binding protein TYPA
KS242_02875	COG0577	efflux transmembrane transporter activity
KS242_02880	COG1136	(ABC) transporter
KS242_02890	COG0018	arginyl-trna synthetase
KS242_02895	COG2843	Capsule synthesis protein
KS242_02900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS242_02905	COG1914	H( )-stimulated, divalent metal cation uptake system
KS242_02910	COG1597	lipid kinase activity
KS242_02915	COG0488	(ABC) transporter
KS242_02920	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_02935	COG0596	Alpha beta hydrolase
KS242_02940	COG0513	Belongs to the DEAD box helicase family
KS242_02945	COG3402	PFAM membrane-flanked domain
KS242_02950	COG3428	Bacterial PH domain
KS242_02960	COG0705	Rhomboid family
KS242_02965	COG0736	holo-[acyl-carrier-protein] synthase activity
KS242_02970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KS242_02970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KS242_02975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KS242_02980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KS242_02985	COG0864	Transcriptional regulator
KS242_02990	COG2337	Toxic component of a toxin-antitoxin (TA) module
KS242_02995	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_03000	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_03005	COG2172	sigma factor antagonist activity
KS242_03010	COG2208	phosphoserine phosphatase activity
KS242_03015	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_03020	COG2172	sigma factor antagonist activity
KS242_03025	COG1191	sigma factor activity
KS242_03030	COG2208	phosphoserine phosphatase activity
KS242_03035	COG2183	response to ionizing radiation
KS242_03045	COG3091	SprT-like family
KS242_03135	COG0802	atpase or kinase
KS242_03140	COG1214	PFAM Peptidase M22, glycoprotease
KS242_03145	COG0456	acetyltransferase
KS242_03150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KS242_03155	COG0488	(ABC) transporter
KS242_03160	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KS242_03165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS242_03170	COG0390	transport system, permease component
KS242_03185	COG2814	Major facilitator Superfamily
KS242_03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS242_03210	COG1811	Na channel or pump
KS242_03215	COG1620	l-lactate permease
KS242_03220	COG0039	L-malate dehydrogenase activity
KS242_03225	COG2368	4-hydroxyphenylacetate
KS242_03230	COG1683	Conserved Protein
KS242_03240	COG1476	TRANSCRIPTIONal
KS242_03250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KS242_03255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS242_03255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS242_03260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KS242_03260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KS242_03270	COG0457	Tetratricopeptide repeat
KS242_03280	COG0833	amino acid
KS242_03290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KS242_03295	COG1522	sequence-specific DNA binding
KS242_03310	COG1115	amino acid carrier protein
KS242_03330	COG3409	Peptidoglycan-binding domain 1 protein
KS242_03370	COG1266	CAAX protease self-immunity
KS242_03385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KS242_03390	COG0459	protein refolding
KS242_03400	COG2268	Band 7 protein
KS242_03405	COG0840	transmembrane signaling receptor activity
KS242_03430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KS242_03435	COG2807	transmembrane transport
KS242_03440	COG0840	transmembrane signaling receptor activity
KS242_03440	COG5278	phosphoserine phosphatase activity
KS242_03445	COG2746	aminoglycoside 3-N-acetyltransferase activity
KS242_03480	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_03485	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KS242_03490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS242_03520	COG0456	acetyltransferase
KS242_03530	COG0693	protein deglycase activity
KS242_03545	COG1069	ribulokinase activity
KS242_03565	COG1609	Transcriptional regulator
KS242_03570	COG1653	transport
KS242_03580	COG1175	transmembrane transport
KS242_03585	COG0395	ABC-type sugar transport system, permease component
KS242_03590	COG5578	integral membrane protein
KS242_03595	COG3534	alpha-L-arabinofuranosidase
KS242_03605	COG0647	UMP catabolic process
KS242_03610	COG3940	Belongs to the glycosyl hydrolase 43 family
KS242_03620	COG2814	Major facilitator Superfamily
KS242_03630	COG1737	Transcriptional regulator
KS242_03635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS242_03655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS242_03665	COG2323	membrane
KS242_03680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KS242_03685	COG1733	regulation of RNA biosynthetic process
KS242_03690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS242_03695	COG0431	NADPH-dependent FMN reductase
KS242_03725	COG1113	amino acid transport
KS242_03730	COG1113	amino acid transport
KS242_03735	COG0693	protein deglycase activity
KS242_03740	COG2910	NAD(P)H-binding
KS242_03750	COG1959	2 iron, 2 sulfur cluster binding
KS242_03760	COG5002	protein histidine kinase activity
KS242_03765	COG0745	RESPONSE REGULATOR receiver
KS242_03780	COG1696	Membrane protein involved in D-alanine export
KS242_03785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS242_03790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KS242_03800	COG2153	protein acetylation
KS242_03805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KS242_03810	COG4989	oxidoreductase activity
KS242_03820	COG2814	Major facilitator Superfamily
KS242_03825	COG3402	PFAM membrane-flanked domain
KS242_03855	COG0840	transmembrane signaling receptor activity
KS242_03865	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS242_03870	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS242_03885	COG0490	domain, Protein
KS242_03890	COG0475	glutathione-regulated potassium exporter activity
KS242_03895	COG0714	Associated with various cellular activities
KS242_03900	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KS242_03905	COG1305	Transglutaminase-like
KS242_03910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KS242_03910	COG0519	Catalyzes the synthesis of GMP from XMP
KS242_03915	COG4129	membrane
KS242_03920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KS242_03925	COG2252	PERMEase
KS242_03935	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KS242_03945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KS242_03950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KS242_03955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KS242_03960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KS242_03965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KS242_03975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KS242_03980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KS242_03985	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KS242_03990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KS242_03995	COG0138	bifunctional purine biosynthesis protein purh
KS242_04000	COG0151	Belongs to the GarS family
KS242_04010	COG4496	protein, YerC YecD
KS242_04015	COG0673	inositol 2-dehydrogenase activity
KS242_04020	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KS242_04025	COG0210	DNA helicase
KS242_04030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KS242_04035	COG4851	CamS sex pheromone cAM373 precursor
KS242_04045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KS242_04050	COG0154	amidase activity
KS242_04055	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KS242_04075	COG1597	lipid kinase activity
KS242_04080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KS242_04120	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KS242_04125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KS242_04135	COG1396	sequence-specific DNA binding
KS242_04145	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KS242_04150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KS242_04155	COG0277	FAD linked oxidase domain protein
KS242_04170	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KS242_04190	COG2188	Transcriptional regulator
KS242_04200	COG2723	6-phospho-beta-galactosidase activity
KS242_04220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KS242_04225	COG0456	acetyltransferase
KS242_04250	COG2226	methyltransferase
KS242_04260	COG0456	acetyltransferase
KS242_04285	COG0840	transmembrane signaling receptor activity
KS242_04290	COG1012	belongs to the aldehyde dehydrogenase family
KS242_04295	COG0662	Cupin 2, conserved barrel domain protein
KS242_04300	COG3401	FG-GAP repeat protein
KS242_04305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS242_04315	COG3706	GGDEF domain
KS242_04320	COG0583	DNA-binding transcription factor activity
KS242_04355	COG0471	metal ion transport
KS242_04370	COG0598	Magnesium transport protein CorA
KS242_04380	COG3394	polysaccharide catabolic process
KS242_04405	COG1077	Cell shape determining protein MreB Mrl
KS242_04410	COG2340	Cysteine-rich secretory protein family
KS242_04435	COG1295	ribonuclease BN
KS242_04440	COG2217	Heavy metal translocating P-type atpase
KS242_04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS242_04450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS242_04455	COG0765	amino acid transport
KS242_04460	COG0477	Major facilitator Superfamily
KS242_04485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KS242_04490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS242_04495	COG0542	response to heat
KS242_04505	COG1131	(ABC) transporter
KS242_04510	COG2188	Transcriptional regulator
KS242_04520	COG1442	glycosyl transferase family 8
KS242_04525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS242_04545	COG1115	amino acid carrier protein
KS242_04575	COG1335	isochorismatase
KS242_04580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KS242_04585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KS242_04595	COG2801	Transposase and inactivated derivatives
KS242_04610	COG0577	efflux transmembrane transporter activity
KS242_04610	COG1136	(ABC) transporter
KS242_04665	COG1132	(ABC) transporter
KS242_04680	COG1368	sulfuric ester hydrolase activity
KS242_04695	COG1063	alcohol dehydrogenase
KS242_04700	COG0628	permease
KS242_04705	COG1090	epimerase
KS242_04710	COG2137	regulation of response to DNA damage stimulus
KS242_04730	COG1988	membrane-bound metal-dependent
KS242_04735	COG1194	a g-specific adenine glycosylase
KS242_04745	COG3557	Belongs to the UPF0374 family
KS242_04750	COG1132	(ABC) transporter
KS242_04755	COG4129	membrane
KS242_04770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KS242_04785	COG2096	Adenosyltransferase
KS242_04790	COG0735	belongs to the Fur family
KS242_04885	COG1966	Carbon starvation protein
KS242_04890	COG0604	alcohol dehydrogenase
KS242_04910	COG0745	RESPONSE REGULATOR receiver
KS242_04915	COG2205	protein histidine kinase activity
KS242_04920	COG1136	(ABC) transporter
KS242_04925	COG0577	efflux transmembrane transporter activity
KS242_05000	COG0840	transmembrane signaling receptor activity
KS242_05005	COG0346	lactoylglutathione lyase activity
KS242_05010	COG0667	Aldo Keto reductase
KS242_05015	COG1794	racemase activity, acting on amino acids and derivatives
KS242_05030	COG0737	Belongs to the 5'-nucleotidase family
KS242_05045	COG2376	Dihydroxyacetone kinase
KS242_05050	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_05060	COG2070	2-Nitropropane dioxygenase
KS242_05065	COG1051	belongs to the nudix hydrolase family
KS242_05075	COG4608	Belongs to the ABC transporter superfamily
KS242_05080	COG0444	Belongs to the ABC transporter superfamily
KS242_05085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS242_05095	COG0747	negative chemotaxis
KS242_05100	COG1473	amidohydrolase
KS242_05105	COG0626	cystathionine gamma-synthase activity
KS242_05110	COG0626	cystathionine gamma-synthase activity
KS242_05115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KS242_05120	COG0095	Lipoate-protein ligase
KS242_05130	COG0697	spore germination
KS242_05135	COG0662	Cupin 2, conserved barrel domain protein
KS242_05135	COG2207	Transcriptional regulator
KS242_05145	COG4221	oxidoreductase activity
KS242_05160	COG1012	belongs to the aldehyde dehydrogenase family
KS242_05165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS242_05180	COG2409	Drug exporters of the RND superfamily
KS242_05185	COG1764	response to oxidative stress
KS242_05190	COG1846	Transcriptional regulator
KS242_05195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS242_05220	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_05225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS242_05230	COG0604	alcohol dehydrogenase
KS242_05240	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_05265	COG1271	oxidase subunit
KS242_05270	COG1294	oxidase, subunit
KS242_05275	COG4988	ABC transporter
KS242_05280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KS242_05290	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_05295	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_05310	COG0398	Pfam SNARE associated Golgi protein
KS242_05325	COG0778	Nitroreductase
KS242_05350	COG2766	serine protein kinase
KS242_05355	COG0730	response to heat
KS242_05360	COG0583	DNA-binding transcription factor activity
KS242_05365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KS242_05370	COG0567	Dehydrogenase, E1 component
KS242_05375	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS242_05380	COG0697	spore germination
KS242_05385	COG0531	amino acid
KS242_05395	COG2718	Belongs to the UPF0229 family
KS242_05400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KS242_05405	COG0288	reversible hydration of carbon dioxide
KS242_05410	COG1132	(ABC) transporter
KS242_05415	COG1132	(ABC) transporter
KS242_05420	COG1191	sigma factor activity
KS242_05430	COG3153	acetyltransferase
KS242_05430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KS242_05455	COG1854	S-ribosylhomocysteine lyase activity
KS242_05460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS242_05465	COG0626	cystathionine gamma-synthase activity
KS242_05475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS242_05480	COG2719	SpoVR family
KS242_05505	COG0500	methyltransferase
KS242_05515	COG4990	cell redox homeostasis
KS242_05520	COG3663	DNA glycosylase
KS242_05525	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_05540	COG1131	(ABC) transporter
KS242_05545	COG3223	Belongs to the PsiE family
KS242_05550	COG0024	Methionine aminopeptidase
KS242_05555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS242_05565	COG2814	Major facilitator Superfamily
KS242_05570	COG5582	Belongs to the UPF0302 family
KS242_05575	COG1876	peptidase activity
KS242_05580	COG0114	fumarate hydratase activity
KS242_05590	COG2508	Transcriptional regulator
KS242_05595	COG4399	Belongs to the UPF0754 family
KS242_05600	COG3679	Belongs to the UPF0342 family
KS242_05605	COG0420	3'-5' exonuclease activity
KS242_05615	COG1510	regulation of RNA biosynthetic process
KS242_05620	COG3481	metal-dependent phosphohydrolase, HD sub domain
KS242_05635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KS242_05670	COG4980	gas vesicle protein
KS242_05675	COG0537	adenosine 5'-monophosphoramidase activity
KS242_05680	COG1131	(ABC) transporter
KS242_05685	COG4473	ABC transporter
KS242_05695	COG1473	amidohydrolase
KS242_05705	COG0671	phosphoesterase, PA-phosphatase related
KS242_05710	COG2329	Antibiotic biosynthesis monooxygenase
KS242_05715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS242_05720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KS242_05725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KS242_05730	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KS242_05740	COG1234	tRNA 3'-trailer cleavage
KS242_05745	COG0095	Lipoate-protein ligase
KS242_05750	COG0501	Belongs to the peptidase M48B family
KS242_05765	COG0398	Pfam SNARE associated Golgi protein
KS242_05775	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KS242_05780	COG1074	ATP-dependent DNA helicase activity
KS242_05790	COG2388	GCN5-related N-acetyl-transferase
KS242_05800	COG2311	Membrane
KS242_05810	COG0367	asparagine synthase
KS242_05815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS242_05835	COG0745	RESPONSE REGULATOR receiver
KS242_05840	COG5002	protein histidine kinase activity
KS242_05855	COG0561	phosphatase activity
KS242_05860	COG1073	alpha beta
KS242_05865	COG2151	metal-sulfur cluster biosynthetic enzyme
KS242_05890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS242_05900	COG0180	Tryptophanyl-tRNA synthetase
KS242_05910	COG4166	transmembrane transport
KS242_05915	COG0601	transmembrane transport
KS242_05920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS242_05925	COG0444	Belongs to the ABC transporter superfamily
KS242_05930	COG4608	Belongs to the ABC transporter superfamily
KS242_05940	COG0456	acetyltransferase
KS242_05945	COG1393	Belongs to the ArsC family
KS242_05950	COG4862	establishment of competence for transformation
KS242_05960	COG1164	Oligoendopeptidase f
KS242_05970	COG0596	Alpha beta hydrolase
KS242_05975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KS242_05980	COG2346	COG2346, Truncated hemoglobins
KS242_05985	COG4116	CYTH
KS242_05990	COG2357	RelA SpoT domain protein
KS242_05995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KS242_06000	COG0564	pseudouridine synthase activity
KS242_06005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KS242_06010	COG0772	Belongs to the SEDS family
KS242_06015	COG2239	Acts as a magnesium transporter
KS242_06020	COG0475	glutathione-regulated potassium exporter activity
KS242_06020	COG0569	domain protein
KS242_06045	COG2323	membrane
KS242_06050	COG2153	protein acetylation
KS242_06055	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KS242_06060	COG2382	esterase
KS242_06065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KS242_06070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KS242_06070	COG1321	iron dependent repressor
KS242_06075	COG1121	(ABC) transporter
KS242_06090	COG0346	lactoylglutathione lyase activity
KS242_06120	COG2814	Major facilitator Superfamily
KS242_06125	COG1309	transcriptional regulator
KS242_06135	COG0582	viral genome integration into host DNA
KS242_06180	COG0740	serine-type endopeptidase activity
KS242_06225	COG5280	Phage tail tape measure protein TP901
KS242_06225	COG3953	SLT domain
KS242_06275	COG1876	peptidase activity
KS242_06310	COG3620	sequence-specific DNA binding
KS242_06365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KS242_06380	COG0305	Participates in initiation and elongation during chromosome replication
KS242_06425	COG0582	viral genome integration into host DNA
KS242_06430	COG2856	Zn peptidase
KS242_06500	COG1278	Cold shock
KS242_06530	COG0667	Aldo Keto reductase
KS242_06560	COG3557	Belongs to the UPF0374 family
KS242_06565	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_06575	COG4753	response regulator
KS242_06575	COG2207	Transcriptional regulator
KS242_06580	COG2972	Histidine kinase
KS242_06600	COG3250	beta-galactosidase activity
KS242_06645	COG0791	NLP P60 protein
KS242_06645	COG3883	PFAM NLP P60 protein
KS242_06665	COG1278	Cold shock
KS242_06675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KS242_06685	COG1177	transmembrane transport
KS242_06690	COG3842	ATPase activity
KS242_06710	COG3773	Cell wall hydrolase
KS242_06720	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_06725	COG1846	Transcriptional regulator
KS242_06730	COG0778	Nitroreductase
KS242_06740	COG5577	PFAM Coat F domain
KS242_06765	COG2076	Multidrug Resistance protein
KS242_06770	COG2076	Multidrug Resistance protein
KS242_06920	COG2135	peptidase activity
KS242_06925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KS242_06930	COG1122	ATPase activity
KS242_06935	COG4721	ABC-type cobalt transport system, permease component
KS242_06945	COG0025	NhaP-type Na H and K H
KS242_06965	COG1090	epimerase
KS242_06980	COG2814	Major facilitator Superfamily
KS242_06990	COG1597	lipid kinase activity
KS242_06995	COG1316	TRANSCRIPTIONal
KS242_07010	COG0515	serine threonine protein kinase
KS242_07025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KS242_07030	COG0066	3-isopropylmalate dehydratase activity
KS242_07035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KS242_07040	COG0473	3-isopropylmalate dehydrogenase activity
KS242_07045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KS242_07050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KS242_07055	COG0440	acetolactate synthase activity
KS242_07060	COG0028	Belongs to the TPP enzyme family
KS242_07065	COG0129	dihydroxy-acid dehydratase activity
KS242_07085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KS242_07090	COG1131	(ABC) transporter
KS242_07095	COG3104	oligopeptide transport
KS242_07100	COG3859	Proton-coupled thiamine transporter YuaJ
KS242_07130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KS242_07145	COG0436	Aminotransferase
KS242_07165	COG1408	metallophosphoesterase
KS242_07170	COG1272	protein, Hemolysin III
KS242_07175	COG0517	IMP dehydrogenase activity
KS242_07180	COG2171	N-acyltransferase activity
KS242_07185	COG1473	amidohydrolase
KS242_07190	COG0668	transmembrane transport
KS242_07195	COG0450	alkyl hydroperoxide reductase
KS242_07205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KS242_07210	COG1132	(ABC) transporter
KS242_07215	COG1132	(ABC) transporter
KS242_07220	COG1271	oxidase subunit
KS242_07225	COG1294	oxidase, subunit
KS242_07230	COG0569	domain protein
KS242_07235	COG0028	Belongs to the TPP enzyme family
KS242_07240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KS242_07245	COG5503	Protein of unknown function (DUF1447)
KS242_07250	COG0561	phosphatase activity
KS242_07255	COG0242	peptide deformylase activity
KS242_07270	COG0022	dehydrogenase e1 component
KS242_07275	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS242_07295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KS242_07300	COG0726	polysaccharide deacetylase
KS242_07305	COG1982	Orn Lys Arg decarboxylase major
KS242_07310	COG4476	Belongs to the UPF0223 family
KS242_07315	COG4493	Belongs to the UPF0637 family
KS242_07325	COG0483	inositol monophosphate 1-phosphatase activity
KS242_07340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KS242_07345	COG4838	Belongs to the UPF0358 family
KS242_07350	COG0772	Belongs to the SEDS family
KS242_07355	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KS242_07380	COG2340	Cysteine-rich secretory protein family
KS242_07395	COG3679	Belongs to the UPF0342 family
KS242_07400	COG4471	UPF0298 protein
KS242_07405	COG0742	ribosomal rna small subunit methyltransferase
KS242_07410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KS242_07415	COG3314	Sporulation integral membrane protein YlbJ
KS242_07420	COG3480	Lon protease (S16) C-terminal proteolytic domain
KS242_07425	COG1323	Belongs to the UPF0348 family
KS242_07430	COG1399	metal-binding, possibly nucleic acid-binding protein
KS242_07435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KS242_07465	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KS242_07470	COG2001	Belongs to the MraZ family
KS242_07475	COG0275	rRNA processing
KS242_07480	COG4839	cell division protein FtsL
KS242_07485	COG0768	penicillin binding
KS242_07490	COG0768	penicillin binding
KS242_07500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KS242_07505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KS242_07510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KS242_07515	COG0772	Belongs to the SEDS family
KS242_07520	COG0431	NADPH-dependent FMN reductase
KS242_07525	COG2814	Major facilitator Superfamily
KS242_07540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KS242_07545	COG0849	cell division
KS242_07550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KS242_07560	COG1191	sigma factor activity
KS242_07565	COG1191	sigma factor activity
KS242_07570	COG1873	PFAM PRC-barrel domain
KS242_07575	COG1496	oxidoreductase activity
KS242_07580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KS242_07585	COG1799	cell septum assembly
KS242_07590	COG0762	integral membrane protein
KS242_07595	COG2302	S4 RNA-binding domain
KS242_07600	COG3599	regulation of cell shape
KS242_07605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KS242_07610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KS242_07615	COG0564	pseudouridine synthase activity
KS242_07620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KS242_07630	COG0540	Belongs to the ATCase OTCase family
KS242_07635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KS242_07640	COG0505	Belongs to the CarA family
KS242_07645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KS242_07650	COG0543	2 iron, 2 sulfur cluster binding
KS242_07660	COG0284	orotidine-5'-phosphate decarboxylase activity
KS242_07680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KS242_07690	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KS242_07695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KS242_07715	COG1561	YicC-like family, N-terminal region
KS242_07720	COG2052	Domain of unknown function (DUF370)
KS242_07725	COG0194	GDP metabolic process
KS242_07730	COG1758	RNA polymerase activity
KS242_07735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KS242_07740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KS242_07745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KS242_07750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KS242_07750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KS242_07755	COG0631	protein serine/threonine phosphatase activity
KS242_07760	COG2815	serine threonine protein kinase
KS242_07760	COG0515	serine threonine protein kinase
KS242_07765	COG1162	GTPase activity
KS242_07770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KS242_07775	COG1564	THIamine pyrophosphokinase
KS242_07785	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KS242_07790	COG1302	Protein conserved in bacteria
KS242_07795	COG1461	Dihydroxyacetone kinase
KS242_07800	COG1760	l-serine dehydratase
KS242_07805	COG1760	l-serine dehydratase
KS242_07810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KS242_07820	COG0416	fatty acid biosynthetic process
KS242_07825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KS242_07830	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_07835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS242_07840	COG0571	ribonuclease III activity
KS242_07845	COG4840	Belongs to the UPF0435 family
KS242_07850	COG1196	nuclear chromosome segregation
KS242_07855	COG0552	protein localization to endoplasmic reticulum
KS242_07860	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KS242_07865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KS242_07870	COG0228	four-way junction DNA binding
KS242_07875	COG1837	Belongs to the UPF0109 family
KS242_07885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KS242_07890	COG0336	Belongs to the RNA methyltransferase TrmD family
KS242_07895	COG0335	large ribosomal subunit rRNA binding
KS242_07905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KS242_07910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KS242_07920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KS242_07925	COG0045	succinate-CoA ligase (ADP-forming) activity
KS242_07930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KS242_07935	COG0758	DNA mediated transformation
KS242_07940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KS242_07945	COG4974	Belongs to the 'phage' integrase family
KS242_07950	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KS242_07955	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KS242_07960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KS242_07965	COG1815	bacterial-type flagellum-dependent cell motility
KS242_07970	COG1558	bacterial-type flagellum-dependent cell motility
KS242_07975	COG1677	Flagellar hook-basal body complex protein FliE
KS242_07980	COG1766	The M ring may be actively involved in energy transduction
KS242_07985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS242_07990	COG1317	bacterial-type flagellum organization
KS242_07995	COG1157	protein secretion by the type III secretion system
KS242_08000	COG2882	bacterial-type flagellum organization
KS242_08015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KS242_08020	COG4786	Flagellar basal body rod
KS242_08025	COG1582	Flagellar protein (FlbD)
KS242_08035	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS242_08040	COG1776	CheC inhibitor of MCP methylation
KS242_08040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS242_08045	COG2201	protein-glutamate methylesterase activity
KS242_08050	COG3190	flagellar
KS242_08055	COG1338	Plays a role in the flagellum-specific transport system
KS242_08060	COG1987	bacterial-type flagellum assembly
KS242_08065	COG1684	flagellar biosynthetic protein fliR
KS242_08070	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KS242_08080	COG1419	protein localization to endoplasmic reticulum
KS242_08085	COG0455	bacterial-type flagellum organization
KS242_08090	COG2201	protein-glutamate methylesterase activity
KS242_08095	COG2198	Histidine kinase
KS242_08095	COG0643	Histidine kinase
KS242_08100	COG0835	chemotaxis
KS242_08105	COG1776	CheC inhibitor of MCP methylation
KS242_08110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KS242_08115	COG1191	sigma factor activity
KS242_08125	COG0052	Belongs to the universal ribosomal protein uS2 family
KS242_08130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KS242_08140	COG0233	cytoplasmic translational termination
KS242_08145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KS242_08150	COG4589	Belongs to the CDS family
KS242_08160	COG0750	zinc metalloprotease
KS242_08165	COG0442	prolyl-tRNA aminoacylation
KS242_08170	COG2176	DNA-directed DNA polymerase activity
KS242_08175	COG0779	Required for maturation of 30S ribosomal subunits
KS242_08180	COG0195	Participates in both transcription termination and antitermination
KS242_08185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KS242_08195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KS242_08205	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KS242_08210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KS242_08215	COG0196	riboflavin kinase activity
KS242_08220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KS242_08225	COG1185	polyribonucleotide nucleotidyltransferase activity
KS242_08230	COG0726	polysaccharide deacetylase
KS242_08235	COG0612	Peptidase, M16
KS242_08240	COG1873	PFAM PRC-barrel domain
KS242_08245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KS242_08250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KS242_08255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KS242_08260	COG0527	aspartate kinase activity
KS242_08270	COG0740	serine-type endopeptidase activity
KS242_08280	COG1674	ftsk spoiiie
KS242_08285	COG1744	ABC transporter substrate-binding protein PnrA-like
KS242_08290	COG3845	ABC transporter
KS242_08295	COG4603	Belongs to the binding-protein-dependent transport system permease family
KS242_08300	COG1079	Belongs to the binding-protein-dependent transport system permease family
KS242_08305	COG0612	Peptidase, M16
KS242_08310	COG0612	Peptidase, M16
KS242_08315	COG0300	oxidoreductase activity
KS242_08330	COG1426	Protein conserved in bacteria
KS242_08335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KS242_08340	COG1546	Belongs to the CinA family
KS242_08340	COG1058	Belongs to the CinA family
KS242_08345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KS242_08350	COG1418	mRNA catabolic process
KS242_08355	COG1692	metallophosphoesterase
KS242_08360	COG2359	stage V sporulation protein S
KS242_08365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KS242_08370	COG4550	Control of competence regulator ComK, YlbF/YmcA
KS242_08380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KS242_08385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KS242_08390	COG0739	heme binding
KS242_08395	COG0783	Belongs to the Dps family
KS242_08400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KS242_08405	COG1923	regulation of RNA biosynthetic process
KS242_08410	COG0464	growth
KS242_08415	COG0697	spore germination
KS242_08420	COG0531	amino acid
KS242_08430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KS242_08435	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KS242_08440	COG0789	Transcriptional regulator
KS242_08445	COG0174	glutamine synthetase
KS242_08450	COG1876	peptidase activity
KS242_08470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KS242_08475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KS242_08480	COG4224	UPF0291 protein
KS242_08495	COG3763	UPF0154 protein
KS242_08535	COG0785	Cytochrome C biogenesis protein
KS242_08540	COG2111	Na H antiporter
KS242_08545	COG2201	protein-glutamate methylesterase activity
KS242_08550	COG4846	Membrane protein involved in cytochrome C biogenesis
KS242_08555	COG4191	Histidine kinase
KS242_08565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KS242_08575	COG0464	growth
KS242_08580	COG0824	Thioesterase
KS242_08590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KS242_08595	COG1469	GTP cyclohydrolase I activity
KS242_08600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KS242_08605	COG0517	IMP dehydrogenase activity
KS242_08605	COG1125	glycine betaine transport
KS242_08610	COG1174	glycine betaine transport
KS242_08615	COG1832	CoA-binding protein
KS242_08620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KS242_08625	COG0187	DNA topoisomerase II activity
KS242_08630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KS242_08640	COG0745	RESPONSE REGULATOR receiver
KS242_08645	COG3850	Histidine kinase
KS242_08645	COG5002	protein histidine kinase activity
KS242_08675	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KS242_08680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS242_08680	COG0723	plastoquinol--plastocyanin reductase activity
KS242_08715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS242_08725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KS242_08730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KS242_08735	COG0131	Imidazoleglycerol-phosphate dehydratase
KS242_08740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KS242_08745	COG0107	imidazoleglycerol-phosphate synthase activity
KS242_08775	COG0753	catalase activity
KS242_08800	COG1902	pentaerythritol trinitrate reductase activity
KS242_08815	COG1902	pentaerythritol trinitrate reductase activity
KS242_08825	COG0673	inositol 2-dehydrogenase activity
KS242_08830	COG0673	inositol 2-dehydrogenase activity
KS242_08840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS242_08845	COG0583	DNA-binding transcription factor activity
KS242_08850	COG0431	NADPH-dependent FMN reductase
KS242_08855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS242_08860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KS242_08865	COG0454	-acetyltransferase
KS242_08870	COG0765	amino acid transport
KS242_08880	COG0765	amino acid transport
KS242_08885	COG1126	abc transporter atp-binding protein
KS242_08890	COG2207	Transcriptional regulator
KS242_08895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS242_08900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KS242_08905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS242_08910	COG0583	DNA-binding transcription factor activity
KS242_08915	COG0067	glutamate synthase
KS242_08915	COG0069	glutamate synthase activity
KS242_08915	COG0070	glutamate synthase
KS242_08920	COG0493	'glutamate synthase
KS242_08925	COG0840	transmembrane signaling receptor activity
KS242_08935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS242_08945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KS242_08950	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_08955	COG1657	PFAM Prenyltransferase squalene oxidase
KS242_08960	COG1063	alcohol dehydrogenase
KS242_08965	COG0708	Exodeoxyribonuclease III
KS242_08970	COG2027	D-alanyl-D-alanine carboxypeptidase
KS242_09000	COG0346	lactoylglutathione lyase activity
KS242_09005	COG0516	GMP reductase activity
KS242_09005	COG0517	IMP dehydrogenase activity
KS242_09025	COG1472	Belongs to the glycosyl hydrolase 3 family
KS242_09030	COG1114	Component of the transport system for branched-chain amino acids
KS242_09040	COG2404	hydrolase activity, acting on ester bonds
KS242_09045	COG2244	polysaccharide biosynthetic process
KS242_09060	COG1473	amidohydrolase
KS242_09065	COG0488	(ABC) transporter
KS242_09075	COG3321	synthase
KS242_09075	COG4221	oxidoreductase activity
KS242_09075	COG0604	alcohol dehydrogenase
KS242_09075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS242_09090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS242_09090	COG0723	plastoquinol--plastocyanin reductase activity
KS242_09095	COG1254	Belongs to the acylphosphatase family
KS242_09100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS242_09100	COG0723	plastoquinol--plastocyanin reductase activity
KS242_09125	COG3180	Ammonia monooxygenase
KS242_09130	COG0861	Integral membrane protein TerC family
KS242_09135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KS242_09135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KS242_09150	COG0419	ATPase involved in DNA repair
KS242_09155	COG0420	3'-5' exonuclease activity
KS242_09160	COG3403	YqcI/YcgG family
KS242_09180	COG1368	sulfuric ester hydrolase activity
KS242_09190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KS242_09210	COG1418	mRNA catabolic process
KS242_09215	COG1801	Protein of unknown function DUF72
KS242_09225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KS242_09230	COG0328	RNA-DNA hybrid ribonuclease activity
KS242_09245	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KS242_09250	COG0116	Belongs to the methyltransferase superfamily
KS242_09265	COG4474	Belongs to the UPF0398 family
KS242_09275	COG1304	FMN binding
KS242_09285	COG0463	Glycosyl transferase, family 2
KS242_09300	COG1562	ergosterol biosynthetic process
KS242_09315	COG0295	cytidine deaminase activity
KS242_09340	COG3331	DNA recombination
KS242_09345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS242_09345	COG4499	WXG100 protein secretion system (Wss), protein YukC
KS242_09350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KS242_09355	COG3935	DnaD domain protein
KS242_09360	COG0017	Asparaginyl-tRNA synthetase
KS242_09375	COG1199	ATP-dependent helicase activity
KS242_09375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KS242_09380	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KS242_09385	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KS242_09390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KS242_09400	COG0617	tRNA 3'-terminal CCA addition
KS242_09405	COG0438	transferase activity, transferring glycosyl groups
KS242_09410	COG1803	Methylglyoxal synthase
KS242_09415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KS242_09420	COG1694	Mazg nucleotide pyrophosphohydrolase
KS242_09425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS242_09430	COG0693	protein deglycase activity
KS242_09440	COG2738	Putative neutral zinc metallopeptidase
KS242_09450	COG4347	Protein of unknown function (DUF1405)
KS242_09455	COG5582	Belongs to the UPF0302 family
KS242_09460	COG0457	Tetratricopeptide repeat
KS242_09465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KS242_09470	COG0287	Prephenate dehydrogenase
KS242_09475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KS242_09480	COG4401	Chorismate mutase type I
KS242_09485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KS242_09490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KS242_09495	COG0789	Transcriptional regulator
KS242_09505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KS242_09510	COG0105	UTP biosynthetic process
KS242_09515	COG0142	geranyltranstransferase activity
KS242_09520	COG2226	methyltransferase
KS242_09525	COG0142	geranyltranstransferase activity
KS242_09530	COG0776	regulation of translation
KS242_09535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KS242_09545	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KS242_09550	COG1160	GTP binding
KS242_09560	COG0539	negative regulation of cytoplasmic translation
KS242_09570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KS242_09580	COG2959	enzyme of heme biosynthesis
KS242_09585	COG3773	Cell wall hydrolase
KS242_09585	COG3409	Peptidoglycan-binding domain 1 protein
KS242_09590	COG2339	peptidase activity
KS242_09600	COG0492	ferredoxin-NADP+ reductase activity
KS242_09605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS242_09610	COG4862	establishment of competence for transformation
KS242_09620	COG0514	ATP-dependent DNA helicase (RecQ)
KS242_09630	COG1141	Ferredoxin
KS242_09645	COG5002	protein histidine kinase activity
KS242_09650	COG0745	RESPONSE REGULATOR receiver
KS242_09655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KS242_09660	COG1333	cytochrome c biogenesis protein
KS242_09665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS242_09670	COG1187	pseudouridine synthase activity
KS242_09675	COG0700	Nucleoside recognition
KS242_09680	COG2715	membrane protein required for spore maturation
KS242_09685	COG1686	Belongs to the peptidase S11 family
KS242_09690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KS242_09695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KS242_09700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KS242_09715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KS242_09720	COG0019	diaminopimelate decarboxylase activity
KS242_09725	COG0697	spore germination
KS242_09740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS242_09760	COG1191	sigma factor activity
KS242_09765	COG2172	sigma factor antagonist activity
KS242_09775	COG1686	Belongs to the peptidase S11 family
KS242_09790	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KS242_09795	COG4974	Belongs to the 'phage' integrase family
KS242_09805	COG0735	belongs to the Fur family
KS242_09810	COG1300	Membrane
KS242_09815	COG0494	nUDIX hydrolase
KS242_09820	COG0667	Aldo Keto reductase
KS242_09830	COG0300	oxidoreductase activity
KS242_09835	COG4187	Peptidase family M20/M25/M40
KS242_09840	COG0584	glycerophosphoryl diester phosphodiesterase
KS242_09845	COG1902	pentaerythritol trinitrate reductase activity
KS242_09850	COG1234	tRNA 3'-trailer cleavage
KS242_09865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS242_09870	COG2195	Cleaves the N-terminal amino acid of tripeptides
KS242_09880	COG1376	ErfK ybiS ycfS ynhG family protein
KS242_09885	COG4129	membrane
KS242_09895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS242_09900	COG0022	dehydrogenase e1 component
KS242_09905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS242_09910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS242_09925	COG0280	phosphate acetyltransferase
KS242_09930	COG3290	protein histidine kinase activity
KS242_09930	COG3829	transcription factor binding
KS242_09940	COG2176	DNA-directed DNA polymerase activity
KS242_09945	COG0527	aspartate kinase activity
KS242_09955	COG1879	ABC-type sugar transport system periplasmic component
KS242_09960	COG1172	Belongs to the binding-protein-dependent transport system permease family
KS242_09965	COG1172	Belongs to the binding-protein-dependent transport system permease family
KS242_09970	COG1129	ABC transporter
KS242_09975	COG2207	Transcriptional regulator
KS242_09975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS242_09980	COG2972	Histidine kinase
KS242_09990	COG1349	DNA-binding transcription factor activity
KS242_09995	COG4806	L-rhamnose isomerase
KS242_10000	COG3254	rhamnose metabolic process
KS242_10005	COG1070	Carbohydrate kinase
KS242_10010	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_10010	COG3347	Dehydrogenase
KS242_10015	COG2814	Major facilitator Superfamily
KS242_10030	COG0745	RESPONSE REGULATOR receiver
KS242_10035	COG0750	zinc metalloprotease
KS242_10040	COG0497	DNA recombination
KS242_10050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KS242_10060	COG0142	geranyltranstransferase activity
KS242_10065	COG1722	exodeoxyribonuclease VII activity
KS242_10070	COG1570	exodeoxyribonuclease VII activity
KS242_10075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KS242_10080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KS242_10085	COG1302	Protein conserved in bacteria
KS242_10090	COG0439	Biotin carboxylase
KS242_10095	COG0511	ligase activity, forming carbon-carbon bonds
KS242_10100	COG1132	(ABC) transporter
KS242_10105	COG1132	(ABC) transporter
KS242_10145	COG3854	ATPases associated with a variety of cellular activities
KS242_10150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KS242_10155	COG0006	proline dipeptidase activity
KS242_10160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KS242_10170	COG3872	metal-dependent enzyme
KS242_10180	COG1752	Esterase of the alpha-beta hydrolase superfamily
KS242_10185	COG1321	iron dependent repressor
KS242_10190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KS242_10195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KS242_10200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KS242_10205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KS242_10210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KS242_10225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KS242_10230	COG1459	type II secretion system
KS242_10235	COG4537	Required for transformation and DNA binding
KS242_10265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS242_10270	COG1368	sulfuric ester hydrolase activity
KS242_10275	COG1940	carbohydrate kinase activity
KS242_10285	COG1363	Peptidase, m42
KS242_10295	COG0457	Tetratricopeptide repeat
KS242_10295	COG0705	Rhomboid family
KS242_10305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KS242_10325	COG0704	Plays a role in the regulation of phosphate uptake
KS242_10330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS242_10335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS242_10340	COG0581	inorganic phosphate transmembrane transporter activity
KS242_10345	COG0573	inorganic phosphate transmembrane transporter activity
KS242_10350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KS242_10355	COG0768	penicillin binding
KS242_10360	COG0477	Major facilitator Superfamily
KS242_10365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KS242_10400	COG1283	sodium-dependent phosphate transmembrane transporter activity
KS242_10410	COG1388	LysM domain
KS242_10415	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KS242_10420	COG4709	membrane
KS242_10430	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KS242_10435	COG0513	Belongs to the DEAD box helicase family
KS242_10440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KS242_10445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KS242_10450	COG2384	SAM-dependent methyltransferase
KS242_10455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KS242_10460	COG0358	DNA primase activity
KS242_10465	COG1671	Belongs to the UPF0178 family
KS242_10475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KS242_10480	COG0517	IMP dehydrogenase activity
KS242_10485	COG0751	glycine-tRNA ligase activity
KS242_10490	COG0752	glycyl-tRNA synthetase alpha subunit
KS242_10495	COG1381	Involved in DNA repair and RecF pathway recombination
KS242_10505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KS242_10515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KS242_10520	COG1480	7TM receptor with intracellular HD hydrolase
KS242_10525	COG1702	phosphate starvation-inducible protein PhoH
KS242_10545	COG4864	UPF0365 protein
KS242_10550	COG1030	water channel activity
KS242_10555	COG1610	YqeY-like protein
KS242_10560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KS242_10565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KS242_10570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KS242_10575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KS242_10580	COG2264	protein methyltransferase activity
KS242_10585	COG0484	heat shock protein binding
KS242_10595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KS242_10600	COG1420	regulation of RNA biosynthetic process
KS242_10605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KS242_10610	COG0481	GTPase activity
KS242_10620	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS242_10625	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KS242_10630	COG0268	Binds directly to 16S ribosomal RNA
KS242_10635	COG1466	dna polymerase III delta subunit
KS242_10640	COG0658	competence protein
KS242_10640	COG2333	competence protein COMEC
KS242_10645	COG2131	deaminase
KS242_10650	COG1596	polysaccharide export
KS242_10650	COG1555	photosystem II stabilization
KS242_10655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KS242_10660	COG2226	methyltransferase
KS242_10665	COG0799	negative regulation of ribosome biogenesis
KS242_10670	COG1713	HD superfamily hydrolase involved in NAD metabolism
KS242_10675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KS242_10680	COG1534	Rna-binding protein
KS242_10685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KS242_10690	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KS242_10695	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KS242_10705	COG2111	Na H antiporter
KS242_10705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KS242_10710	COG1006	Multisubunit Na H antiporter MnhC subunit
KS242_10715	COG0651	ATP synthesis coupled electron transport
KS242_10720	COG1863	multisubunit Na H antiporter MnhE subunit
KS242_10725	COG2212	antiporter activity
KS242_10730	COG1320	monovalent cation:proton antiporter activity
KS242_10745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KS242_10760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KS242_10770	COG4122	O-methyltransferase activity
KS242_10775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KS242_10780	COG3906	Belongs to the UPF0473 family
KS242_10785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KS242_10790	COG4472	Bacterial protein of unknown function (DUF965)
KS242_10800	COG0628	permease
KS242_10810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KS242_10820	COG0482	sulfurtransferase activity
KS242_10825	COG1104	cysteine desulfurase activity
KS242_10830	COG1959	2 iron, 2 sulfur cluster binding
KS242_10835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KS242_10850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KS242_10855	COG0124	histidyl-tRNA synthetase
KS242_10865	COG1490	D-aminoacyl-tRNA deacylase activity
KS242_10870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KS242_10875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KS242_10880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KS242_10880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KS242_10885	COG5416	Lipopolysaccharide assembly protein A domain
KS242_10890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KS242_10890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KS242_10900	COG2244	polysaccharide biosynthetic process
KS242_10905	COG2323	membrane
KS242_10915	COG1862	Preprotein translocase
KS242_10920	COG0343	queuine tRNA-ribosyltransferase activity
KS242_10925	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KS242_10935	COG2255	four-way junction helicase activity
KS242_10940	COG0632	four-way junction helicase activity
KS242_10955	COG1388	LysM domain
KS242_10960	COG0077	Prephenate dehydratase
KS242_10965	COG4492	Belongs to the UPF0735 family
KS242_10970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KS242_10975	COG3290	protein histidine kinase activity
KS242_10980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KS242_10985	COG2868	ribosomal protein
KS242_10990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KS242_10995	COG1530	ribonuclease E activity
KS242_11000	COG1994	Peptidase M50
KS242_11005	COG0739	heme binding
KS242_11015	COG2860	membrane
KS242_11020	COG2894	cell division
KS242_11025	COG0850	regulation of cytokinetic process
KS242_11035	COG1792	Involved in formation and maintenance of cell shape
KS242_11040	COG1077	Cell shape determining protein MreB Mrl
KS242_11045	COG2003	Belongs to the UPF0758 family
KS242_11070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KS242_11080	COG1459	type II secretion system
KS242_11090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KS242_11115	COG2199	diguanylate cyclase activity
KS242_11115	COG2203	Gaf domain
KS242_11120	COG0285	dihydrofolate synthase activity
KS242_11130	COG0189	ligase activity
KS242_11135	COG1119	ATPase activity
KS242_11145	COG1113	amino acid transport
KS242_11160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS242_11165	COG0525	valine-tRNA ligase activity
KS242_11180	COG1388	LysM domain
KS242_11190	COG0113	porphobilinogen synthase activity
KS242_11200	COG0181	hydroxymethylbilane synthase activity
KS242_11205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KS242_11220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KS242_11225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KS242_11230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KS242_11235	COG0544	peptidyl-prolyl cis-trans isomerase activity
KS242_11260	COG3773	Cell wall hydrolase
KS242_11270	COG2207	Transcriptional regulator
KS242_11270	COG4753	response regulator
KS242_11275	COG2972	Histidine kinase
KS242_11280	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_11285	COG0673	inositol 2-dehydrogenase activity
KS242_11290	COG5578	integral membrane protein
KS242_11295	COG0395	ABC-type sugar transport system, permease component
KS242_11300	COG1175	transmembrane transport
KS242_11305	COG1653	transport
KS242_11330	COG2322	membrane
KS242_11335	COG0622	Phosphoesterase
KS242_11340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KS242_11345	COG5401	PFAM Sporulation and spore germination
KS242_11350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KS242_11355	COG1846	Transcriptional regulator
KS242_11360	COG3263	regulation of cellular component size
KS242_11380	COG1971	Probably functions as a manganese efflux pump
KS242_11400	COG2197	response regulator
KS242_11430	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_11440	COG1012	belongs to the aldehyde dehydrogenase family
KS242_11445	COG1525	nuclease
KS242_11450	COG2318	DinB family
KS242_11475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS242_11490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KS242_11495	COG1053	succinate dehydrogenase
KS242_11500	COG2009	succinate dehydrogenase
KS242_11505	COG1719	4-vinyl reductase, 4VR
KS242_11515	COG0322	excinuclease ABC activity
KS242_11520	COG3118	belongs to the thioredoxin family
KS242_11525	COG3766	membrane
KS242_11530	COG1193	negative regulation of DNA recombination
KS242_11535	COG1796	DNA polymerase
KS242_11535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS242_11540	COG1286	toxin biosynthetic process
KS242_11545	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KS242_11550	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KS242_11555	COG1403	HNH endonuclease
KS242_11575	COG0072	phenylalanine-tRNA ligase activity
KS242_11575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS242_11580	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KS242_11585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KS242_11595	COG0741	lytic transglycosylase activity
KS242_11600	COG1363	Peptidase, m42
KS242_11615	COG0398	Pfam SNARE associated Golgi protein
KS242_11625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KS242_11630	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KS242_11635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KS242_11645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KS242_11655	COG1484	DNA-dependent DNA replication
KS242_11660	COG3611	Membrane attachment protein
KS242_11665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KS242_11670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS242_11675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KS242_11680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KS242_11695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KS242_11700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS242_11700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS242_11705	COG5002	protein histidine kinase activity
KS242_11710	COG0745	RESPONSE REGULATOR receiver
KS242_11715	COG0039	L-malate dehydrogenase activity
KS242_11720	COG0538	isocitrate dehydrogenase activity
KS242_11725	COG0372	Belongs to the citrate synthase family
KS242_11735	COG0628	permease
KS242_11740	COG3030	protein affecting phage T7 exclusion by the F plasmid
KS242_11750	COG0205	6-phosphofructokinase activity
KS242_11755	COG0825	malonyl-CoA metabolic process
KS242_11760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KS242_11765	COG0281	malic enzyme
KS242_11770	COG0587	DNA-directed DNA polymerase activity
KS242_11785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KS242_11790	COG4109	DRTGG domain
KS242_11795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KS242_11800	COG0006	proline dipeptidase activity
KS242_11815	COG0827	DNA restriction-modification system
KS242_11820	COG3493	citrate carrier protein
KS242_11830	COG4565	transcriptional regulatory protein
KS242_11835	COG3290	protein histidine kinase activity
KS242_11840	COG3874	Sporulation protein YtfJ
KS242_11855	COG0301	tRNA thio-modification
KS242_11860	COG1104	cysteine desulfurase activity
KS242_11865	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KS242_11870	COG1309	transcriptional regulator
KS242_11875	COG1956	GAF domain-containing protein
KS242_11880	COG2203	Gaf domain
KS242_11880	COG2199	diguanylate cyclase activity
KS242_11885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KS242_11890	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_11895	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_11900	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KS242_11910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KS242_11925	COG1605	Chorismate mutase
KS242_11925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KS242_11940	COG3118	belongs to the thioredoxin family
KS242_11945	COG4980	gas vesicle protein
KS242_11955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KS242_11960	COG1674	ftsk spoiiie
KS242_11965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS242_11970	COG4848	Belongs to the UPF0354 family
KS242_11975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS242_11980	COG0840	transmembrane signaling receptor activity
KS242_11990	COG3069	C4-dicarboxylate transmembrane transporter activity
KS242_11995	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KS242_12000	COG1363	Peptidase, m42
KS242_12010	COG1486	melibiose metabolic process
KS242_12015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KS242_12025	COG0510	thiamine kinase activity
KS242_12045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS242_12050	COG1349	DNA-binding transcription factor activity
KS242_12055	COG1187	pseudouridine synthase activity
KS242_12060	COG2244	polysaccharide biosynthetic process
KS242_12065	COG2081	HI0933 family
KS242_12095	COG0495	leucyl-tRNA aminoacylation
KS242_12100	COG0840	transmembrane signaling receptor activity
KS242_12105	COG1744	ABC transporter substrate-binding protein PnrA-like
KS242_12110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KS242_12120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KS242_12130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KS242_12135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KS242_12140	COG0494	nUDIX hydrolase
KS242_12165	COG4948	Mandelate Racemase Muconate Lactonizing
KS242_12170	COG0318	PFAM AMP-dependent synthetase and ligase
KS242_12175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KS242_12180	COG0596	Alpha beta hydrolase
KS242_12185	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KS242_12190	COG1169	isochorismate synthase
KS242_12195	COG1575	Belongs to the MenA family. Type 1 subfamily
KS242_12200	COG2050	protein possibly involved in aromatic compounds catabolism
KS242_12205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS242_12210	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KS242_12225	COG3173	Aminoglycoside phosphotransferase
KS242_12230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KS242_12240	COG2155	Conserved Protein
KS242_12245	COG1098	S1 RNA binding domain
KS242_12255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KS242_12265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_12270	COG0813	purine-nucleoside phosphorylase activity
KS242_12275	COG1268	BioY protein
KS242_12280	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KS242_12290	COG1252	NADH dehydrogenase
KS242_12295	COG0492	ferredoxin-NADP+ reductase activity
KS242_12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS242_12310	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KS242_12315	COG0316	Belongs to the HesB IscA family
KS242_12320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KS242_12330	COG4837	Protein of unknown function (DUF1462)
KS242_12335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KS242_12345	COG0083	homoserine kinase activity
KS242_12350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KS242_12355	COG0460	homoserine dehydrogenase
KS242_12360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS242_12365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KS242_12370	COG5577	PFAM Coat F domain
KS242_12375	COG0647	UMP catabolic process
KS242_12380	COG2445	Protein of unknown function DUF86
KS242_12385	COG4470	Protein conserved in bacteria
KS242_12390	COG0739	heme binding
KS242_12405	COG3377	Domain of unknown function (DUF1805)
KS242_12410	COG0737	Belongs to the 5'-nucleotidase family
KS242_12415	COG0730	response to heat
KS242_12425	COG3739	integral membrane protein
KS242_12430	COG3655	Transcriptional regulator
KS242_12440	COG0719	Fe-S assembly protein
KS242_12445	COG0822	iron-sulfur transferase activity
KS242_12450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KS242_12455	COG0719	Fe-S assembly protein
KS242_12460	COG0396	ATPase activity
KS242_12465	COG1464	Belongs to the NlpA lipoprotein family
KS242_12470	COG2011	ABC-type metal ion transport system permease component
KS242_12475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KS242_12485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS242_12490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KS242_12495	COG0509	glycine decarboxylation via glycine cleavage system
KS242_12500	COG1393	Belongs to the ArsC family
KS242_12510	COG5577	PFAM Coat F domain
KS242_12515	COG1846	Transcriptional regulator
KS242_12525	COG1121	(ABC) transporter
KS242_12530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KS242_12535	COG0735	belongs to the Fur family
KS242_12540	COG1942	4-Oxalocrotonate Tautomerase
KS242_12560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS242_12565	COG1960	acyl-CoA dehydrogenase activity
KS242_12580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KS242_12585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KS242_12595	COG2814	Major facilitator Superfamily
KS242_12600	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS242_12605	COG0840	transmembrane signaling receptor activity
KS242_12610	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KS242_12615	COG4607	ABC-type enterochelin transport system periplasmic component
KS242_12620	COG4604	ABC transporter, ATP-binding protein
KS242_12625	COG4605	iron ion homeostasis
KS242_12630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS242_12635	COG3403	YqcI/YcgG family
KS242_12645	COG5577	PFAM Coat F domain
KS242_12665	COG1968	undecaprenyl-diphosphatase activity
KS242_12670	COG0586	Pfam SNARE associated Golgi protein
KS242_12675	COG1413	lyase activity
KS242_12685	COG0753	catalase activity
KS242_12705	COG1215	transferase activity, transferring glycosyl groups
KS242_12710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KS242_12720	COG0024	Methionine aminopeptidase
KS242_12730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KS242_12740	COG0557	exoribonuclease II activity
KS242_12745	COG1647	Serine aminopeptidase, S33
KS242_12750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KS242_12755	COG1349	DNA-binding transcription factor activity
KS242_12760	COG1105	Belongs to the carbohydrate kinase PfkB family
KS242_12765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS242_12765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS242_12765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_12770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_12790	COG0300	oxidoreductase activity
KS242_12795	COG0148	phosphopyruvate hydratase activity
KS242_12800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KS242_12805	COG0149	triose-phosphate isomerase activity
KS242_12810	COG0126	phosphoglycerate kinase activity
KS242_12815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KS242_12825	COG0534	Mate efflux family protein
KS242_12835	COG3546	catalase activity
KS242_12840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS242_12850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KS242_12865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KS242_12870	COG0004	ammonium transporteR
KS242_12875	COG0347	Belongs to the P(II) protein family
KS242_12900	COG3546	catalase activity
KS242_12905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KS242_12910	COG0028	Belongs to the TPP enzyme family
KS242_12915	COG1012	belongs to the aldehyde dehydrogenase family
KS242_12930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KS242_12930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KS242_12935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KS242_12935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KS242_12940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KS242_12945	COG0673	inositol 2-dehydrogenase activity
KS242_12995	COG3546	catalase activity
KS242_13000	COG0740	serine-type endopeptidase activity
KS242_13005	COG1714	RDD family
KS242_13010	COG0616	signal peptide processing
KS242_13015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_13020	COG1481	regulation of sporulation
KS242_13025	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KS242_13030	COG1660	Displays ATPase and GTPase activities
KS242_13035	COG1051	belongs to the nudix hydrolase family
KS242_13040	COG0492	ferredoxin-NADP+ reductase activity
KS242_13050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KS242_13055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KS242_13060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KS242_13065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KS242_13070	COG0110	maltose O-acetyltransferase activity
KS242_13075	COG0546	phosphoglycolate phosphatase activity
KS242_13080	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KS242_13085	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KS242_13090	COG1950	PFAM Membrane protein of
KS242_13095	COG3595	metallopeptidase activity
KS242_13105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS242_13115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KS242_13120	COG0556	nucleotide-excision repair
KS242_13125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KS242_13130	COG2190	(PTS) system
KS242_13140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS242_13145	COG0793	Belongs to the peptidase S41A family
KS242_13145	COG3409	Peptidoglycan-binding domain 1 protein
KS242_13150	COG0739	heme binding
KS242_13155	COG2177	Part of the ABC transporter FtsEX involved in
KS242_13160	COG2884	Cell division ATP-binding protein ftsE
KS242_13175	COG0653	protein targeting
KS242_13180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KS242_13190	COG1516	flagellar protein fliS
KS242_13195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KS242_13200	COG1334	flagellar protein FlaG
KS242_13205	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_13210	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_13220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KS242_13225	COG0110	maltose O-acetyltransferase activity
KS242_13230	COG2089	acid synthase
KS242_13235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KS242_13245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS242_13260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KS242_13265	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KS242_13270	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KS242_13280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KS242_13285	COG1256	bacterial-type flagellum assembly
KS242_13285	COG4786	Flagellar basal body rod
KS242_13295	COG2747	anti-sigma28 factor FlgM
KS242_13305	COG1040	competence protein
KS242_13310	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KS242_13315	COG1307	EDD domain protein, DegV family
KS242_13320	COG2197	response regulator
KS242_13325	COG4585	Histidine kinase
KS242_13330	COG1739	Uncharacterized protein family UPF0029
KS242_13335	COG0363	glucosamine-6-phosphate deaminase activity
KS242_13340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KS242_13355	COG3764	Sortase (surface protein transpeptidase)
KS242_13360	COG2186	Transcriptional regulator
KS242_13365	COG1301	dicarboxylic acid transport
KS242_13380	COG1263	PTS System
KS242_13380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS242_13385	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KS242_13390	COG1737	Transcriptional regulator
KS242_13435	COG1082	Xylose isomerase domain protein TIM barrel
KS242_13440	COG0673	inositol 2-dehydrogenase activity
KS242_13450	COG1175	transmembrane transport
KS242_13470	COG2217	Heavy metal translocating P-type atpase
KS242_13475	COG1937	Protein conserved in bacteria
KS242_13480	COG0745	RESPONSE REGULATOR receiver
KS242_13485	COG0642	Histidine kinase
KS242_13505	COG0205	6-phosphofructokinase activity
KS242_13510	COG0604	alcohol dehydrogenase
KS242_13520	COG2059	Chromate
KS242_13525	COG2059	Chromate
KS242_13535	COG0561	phosphatase activity
KS242_13540	COG1011	Hydrolase
KS242_13545	COG2755	lipolytic protein G-D-S-L family
KS242_13555	COG2267	carboxylic ester hydrolase activity
KS242_13570	COG1033	growth of symbiont in host cell
KS242_13570	COG2409	Drug exporters of the RND superfamily
KS242_13575	COG1846	Transcriptional regulator
KS242_13580	COG1472	Belongs to the glycosyl hydrolase 3 family
KS242_13590	COG1695	Transcriptional regulator
KS242_13600	COG3479	Phenolic acid decarboxylase
KS242_13615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_13615	COG3711	transcriptional antiterminator
KS242_13620	COG1447	Phosphotransferase system cellobiose-specific component IIA
KS242_13625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS242_13630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS242_13635	COG1309	transcriptional regulator
KS242_13640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KS242_13650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS242_13670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KS242_13675	COG1737	Transcriptional regulator
KS242_13680	COG2508	Transcriptional regulator
KS242_13685	COG0840	transmembrane signaling receptor activity
KS242_13690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KS242_13695	COG0523	cobalamin synthesis protein
KS242_13700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KS242_13705	COG0523	cobalamin synthesis protein
KS242_13710	COG0523	cobalamin synthesis protein
KS242_13715	COG1012	belongs to the aldehyde dehydrogenase family
KS242_13730	COG1215	transferase activity, transferring glycosyl groups
KS242_13755	COG0346	lactoylglutathione lyase activity
KS242_13765	COG2723	6-phospho-beta-galactosidase activity
KS242_13775	COG2207	Transcriptional regulator
KS242_13780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KS242_13790	COG1280	lysine exporter protein (LysE YggA)
KS242_13795	COG1113	amino acid transport
KS242_13800	COG1283	sodium-dependent phosphate transmembrane transporter activity
KS242_13805	COG1316	TRANSCRIPTIONal
KS242_13845	COG1216	Glycosyl transferase, family 2
KS242_13845	COG1442	glycosyl transferase family 8
KS242_13870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KS242_13875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KS242_13880	COG4464	protein tyrosine phosphatase activity
KS242_13885	COG0489	protein tyrosine kinase activity
KS242_13890	COG3944	biosynthesis protein
KS242_13900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KS242_13905	COG0791	NLP P60 protein
KS242_13905	COG1388	LysM domain
KS242_13920	COG2172	sigma factor antagonist activity
KS242_13935	COG0534	Mate efflux family protein
KS242_13950	COG3386	PFAM SMP-30 Gluconolaconase
KS242_13955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS242_13960	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KS242_13965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KS242_13975	COG1940	carbohydrate kinase activity
KS242_13990	COG2851	Citrate transporter
KS242_14020	COG0745	RESPONSE REGULATOR receiver
KS242_14020	COG2972	Histidine kinase
KS242_14040	COG1316	TRANSCRIPTIONal
KS242_14045	COG1682	transport, permease protein
KS242_14050	COG1134	teichoic acid transport
KS242_14065	COG4193	domain, Protein
KS242_14095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KS242_14100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS242_14105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KS242_14125	COG0728	peptidoglycan biosynthetic process
KS242_14155	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_14160	COG2002	toxin-antitoxin pair type II binding
KS242_14165	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS242_14165	COG2247	cell wall binding repeat
KS242_14170	COG0438	transferase activity, transferring glycosyl groups
KS242_14200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KS242_14215	COG4786	Flagellar basal body rod
KS242_14220	COG4786	Flagellar basal body rod
KS242_14225	COG1077	Cell shape determining protein MreB Mrl
KS242_14230	COG1609	Transcriptional regulator
KS242_14240	COG0739	heme binding
KS242_14245	COG2385	sporulation resulting in formation of a cellular spore
KS242_14250	COG0791	NLP P60 protein
KS242_14255	COG4948	Mandelate Racemase Muconate Lactonizing
KS242_14260	COG1619	proteins homologs of microcin C7 resistance protein MccF
KS242_14265	COG4166	transmembrane transport
KS242_14270	COG0444	Belongs to the ABC transporter superfamily
KS242_14275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS242_14280	COG0601	transmembrane transport
KS242_14285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KS242_14295	COG4836	Membrane
KS242_14300	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KS242_14305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KS242_14310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KS242_14315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KS242_14320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KS242_14325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KS242_14330	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KS242_14335	COG0356	it plays a direct role in the translocation of protons across the membrane
KS242_14345	COG1404	Belongs to the peptidase S8 family
KS242_14350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KS242_14355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KS242_14360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KS242_14365	COG4475	Protein of unknown function (DUF436)
KS242_14370	COG0698	ribose 5-phosphate isomerase
KS242_14375	COG0840	transmembrane signaling receptor activity
KS242_14380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KS242_14385	COG0009	L-threonylcarbamoyladenylate synthase
KS242_14400	COG2890	protein-(glutamine-N5) methyltransferase activity
KS242_14405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KS242_14410	COG1435	thymidine kinase activity
KS242_14415	COG0254	rRNA binding
KS242_14420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KS242_14430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KS242_14435	COG0191	fructose-bisphosphate aldolase activity
KS242_14440	COG2204	response regulator
KS242_14450	COG3343	RNA polymerase activity
KS242_14460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS242_14465	COG0018	arginyl-trna synthetase
KS242_14475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KS242_14480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS242_14495	COG3465	dGTPase activity
KS242_14500	COG1078	dGTPase activity
KS242_14505	COG0095	Lipoate-protein ligase
KS242_14510	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_14510	COG2202	Pas domain
KS242_14515	COG0280	phosphate acetyltransferase
KS242_14520	COG3253	May function as heme-dependent peroxidase
KS242_14530	COG2363	Small membrane protein
KS242_14550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KS242_14560	COG3594	Acyltransferase
KS242_14565	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KS242_14570	COG3285	dna ligase
KS242_14570	COG1793	dna ligase
KS242_14590	COG1764	response to oxidative stress
KS242_14595	COG0861	Integral membrane protein TerC family
KS242_14600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KS242_14605	COG0628	permease
KS242_14610	COG2814	Major facilitator Superfamily
KS242_14615	COG1605	Chorismate mutase
KS242_14615	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KS242_14630	COG1253	flavin adenine dinucleotide binding
KS242_14635	COG0514	ATP-dependent DNA helicase (RecQ)
KS242_14645	COG0488	(ABC) transporter
KS242_14650	COG0351	phosphomethylpyrimidine kinase
KS242_14670	COG1607	acyl-coa hydrolase
KS242_14675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS242_14680	COG2962	Rard protein
KS242_14695	COG2755	lipolytic protein G-D-S-L family
KS242_14705	COG2197	response regulator
KS242_14710	COG4585	Histidine kinase
KS242_14755	COG1309	transcriptional regulator
KS242_14760	COG2124	cytochrome p450
KS242_14775	COG0488	(ABC) transporter
KS242_14780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KS242_14785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS242_14795	COG2801	Transposase and inactivated derivatives
KS242_14805	COG1668	transmembrane transport
KS242_14810	COG4152	abc transporter atp-binding protein
KS242_14815	COG2211	Major facilitator Superfamily
KS242_14820	COG0159	tryptophan synthase activity
KS242_14840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KS242_14850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KS242_14860	COG1388	LysM domain
KS242_14860	COG3584	3D domain protein
KS242_14865	COG0737	Belongs to the 5'-nucleotidase family
KS242_14880	COG3639	organic phosphonate transmembrane transporter activity
KS242_14890	COG0778	Nitroreductase
KS242_14895	COG1120	ATPase activity
KS242_14900	COG1396	sequence-specific DNA binding
KS242_14905	COG0252	asparaginase activity
KS242_14910	COG1027	Aspartate ammonia-lyase
KS242_14915	COG1757	Na H antiporter
KS242_14920	COG1525	nuclease
KS242_14920	COG0737	Belongs to the 5'-nucleotidase family
KS242_14920	COG4085	toxin activity
KS242_14930	COG2056	Na+-H+ antiporter family
KS242_14935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KS242_14940	COG0346	lactoylglutathione lyase activity
KS242_14980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS242_14985	COG2084	Dehydrogenase
KS242_14990	COG0471	metal ion transport
KS242_14995	COG3973	AAA domain
KS242_15000	COG2814	Major facilitator Superfamily
KS242_15005	COG0251	oxidation-reduction process
KS242_15015	COG4876	unkown
KS242_15020	COG2130	NADP-dependent
KS242_15035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KS242_15040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS242_15045	COG0788	formyltetrahydrofolate deformylase activity
KS242_15050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KS242_15055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KS242_15060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KS242_15065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KS242_15075	COG2188	Transcriptional regulator
KS242_15085	COG0179	Fumarylacetoacetate (FAA) hydrolase
KS242_15095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS242_15105	COG1360	Flagellar Motor Protein
KS242_15110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KS242_15120	COG3711	transcriptional antiterminator
KS242_15125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS242_15130	COG0246	Mannitol dehydrogenase
KS242_15140	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_15145	COG2318	DinB family
KS242_15150	COG3842	ATPase activity
KS242_15165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KS242_15170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KS242_15185	COG0765	amino acid transport
KS242_15195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS242_15200	COG4841	protein insertion into membrane
KS242_15205	COG1392	Phosphate transport regulator
KS242_15210	COG0306	phosphate transporter
KS242_15215	COG2011	ABC-type metal ion transport system permease component
KS242_15220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KS242_15225	COG1464	Belongs to the NlpA lipoprotein family
KS242_15230	COG0789	Transcriptional regulator
KS242_15240	COG0584	glycerophosphoryl diester phosphodiesterase
KS242_15250	COG3842	ATPase activity
KS242_15255	COG1175	transmembrane transport
KS242_15260	COG0395	ABC-type sugar transport system, permease component
KS242_15265	COG1653	transport
KS242_15280	COG0385	Bile acid
KS242_15300	COG1174	glycine betaine transport
KS242_15310	COG1742	UPF0060 membrane protein
KS242_15330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS242_15335	COG1522	sequence-specific DNA binding
KS242_15340	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KS242_15345	COG3766	membrane
KS242_15355	COG1842	Phage shock protein A
KS242_15370	COG1404	Belongs to the peptidase S8 family
KS242_15375	COG1404	Belongs to the peptidase S8 family
KS242_15380	COG0659	secondary active sulfate transmembrane transporter activity
KS242_15385	COG0640	Transcriptional regulator
KS242_15415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS242_15420	COG2195	Cleaves the N-terminal amino acid of tripeptides
KS242_15425	COG1846	Transcriptional regulator
KS242_15430	COG0400	carboxylic ester hydrolase activity
KS242_15445	COG1012	belongs to the aldehyde dehydrogenase family
KS242_15450	COG1073	alpha beta
KS242_15465	COG0667	Aldo Keto reductase
KS242_15475	COG1126	abc transporter atp-binding protein
KS242_15480	COG0765	amino acid transport
KS242_15485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS242_15495	COG0477	Major facilitator Superfamily
KS242_15505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KS242_15530	COG2304	oxidoreductase activity
KS242_15545	COG3300	MHYT domain
KS242_15545	COG5001	Diguanylate cyclase
KS242_15555	COG0463	Glycosyl transferase, family 2
KS242_15560	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS242_15570	COG2514	catechol 2,3-dioxygenase activity
KS242_15575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KS242_15585	COG0561	phosphatase activity
KS242_15595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KS242_15595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KS242_15625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS242_15630	COG0438	transferase activity, transferring glycosyl groups
KS242_15645	COG1086	Polysaccharide biosynthesis protein
KS242_15655	COG0438	transferase activity, transferring glycosyl groups
KS242_15660	COG0463	Glycosyl transferase, family 2
KS242_15660	COG1216	Glycosyl transferase, family 2
KS242_15690	COG1176	ABC-type spermidine putrescine transport system, permease component I
KS242_15695	COG1177	transmembrane transport
KS242_15700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KS242_15705	COG2723	6-phospho-beta-galactosidase activity
KS242_15710	COG1263	PTS System
KS242_15710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS242_15710	COG2190	(PTS) system
KS242_15720	COG0657	acetylesterase activity
KS242_15735	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_15740	COG2040	homocysteine
KS242_15745	COG0833	amino acid
KS242_15750	COG1874	Beta-galactosidase
KS242_15755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KS242_15765	COG2017	converts alpha-aldose to the beta-anomer
KS242_15790	COG0110	maltose O-acetyltransferase activity
KS242_15810	COG0457	Tetratricopeptide repeat
KS242_15830	COG1114	Component of the transport system for branched-chain amino acids
KS242_15835	COG1279	arginine transmembrane transporter activity
KS242_15850	COG1556	Lactate utilization protein
KS242_15855	COG1139	Iron-sulfur cluster binding protein
KS242_15865	COG2186	Transcriptional regulator
KS242_15870	COG1620	l-lactate permease
KS242_15880	COG1511	domain protein
KS242_15885	COG0583	DNA-binding transcription factor activity
KS242_15890	COG1959	2 iron, 2 sulfur cluster binding
KS242_15895	COG0492	ferredoxin-NADP+ reductase activity
KS242_15900	COG0823	Involved in the tonB-independent uptake of proteins
KS242_15900	COG1506	peptidase
KS242_15900	COG4946	Tricorn protease homolog
KS242_15920	COG1473	amidohydrolase
KS242_15925	COG1288	antiporter activity
KS242_15930	COG5039	Polysaccharide pyruvyl transferase
KS242_15940	COG2323	membrane
KS242_15945	COG1757	Na H antiporter
KS242_15950	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KS242_15955	COG1917	Cupin 2, conserved barrel domain protein
KS242_15970	COG0697	spore germination
KS242_15980	COG3858	chitin binding
KS242_15990	COG1785	Belongs to the alkaline phosphatase family
KS242_15995	COG0450	alkyl hydroperoxide reductase
KS242_16000	COG3634	alkyl hydroperoxide reductase activity
KS242_16005	COG1984	allophanate hydrolase subunit 2
KS242_16010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KS242_16015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KS242_16020	COG1914	H( )-stimulated, divalent metal cation uptake system
KS242_16025	COG3588	fructose-bisphosphate aldolase
KS242_16030	COG0670	Belongs to the BI1 family
KS242_16060	COG5444	nuclease activity
KS242_16085	COG1131	(ABC) transporter
KS242_16090	COG2205	protein histidine kinase activity
KS242_16095	COG0745	RESPONSE REGULATOR receiver
KS242_16100	COG0402	S-adenosylhomocysteine deaminase activity
KS242_16105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KS242_16130	COG1929	Belongs to the glycerate kinase type-1 family
KS242_16135	COG2610	gluconate transmembrane transporter activity
KS242_16140	COG3835	regulator
KS242_16150	COG1113	amino acid transport
KS242_16160	COG5504	Zn-dependent protease
KS242_16165	COG2226	methyltransferase
KS242_16225	COG0385	Bile acid
KS242_16270	COG1074	ATP-dependent DNA helicase activity
KS242_16280	COG0494	nUDIX hydrolase
KS242_16295	COG4166	transmembrane transport
KS242_16300	COG4608	Belongs to the ABC transporter superfamily
KS242_16305	COG0444	Belongs to the ABC transporter superfamily
KS242_16310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS242_16315	COG0601	transmembrane transport
KS242_16320	COG2362	D-Aminopeptidase
KS242_16335	COG1228	amidohydrolase
KS242_16340	COG0823	Involved in the tonB-independent uptake of proteins
KS242_16340	COG1506	peptidase
KS242_16340	COG4946	Tricorn protease homolog
KS242_16345	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KS242_16375	COG3250	beta-galactosidase activity
KS242_16380	COG0673	inositol 2-dehydrogenase activity
KS242_16385	COG3716	PTS system mannose fructose sorbose family IID component
KS242_16390	COG3715	PTS system
KS242_16405	COG0659	secondary active sulfate transmembrane transporter activity
KS242_16410	COG1414	Transcriptional regulator
KS242_16420	COG3142	Participates in the control of copper homeostasis
KS242_16425	COG5002	protein histidine kinase activity
KS242_16440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KS242_16445	COG1215	transferase activity, transferring glycosyl groups
KS242_16455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KS242_16460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KS242_16465	COG1266	CAAX protease self-immunity
KS242_16475	COG0733	neurotransmitter:sodium symporter activity
KS242_16490	COG0655	NAD(P)H dehydrogenase (quinone) activity
KS242_16495	COG0346	lactoylglutathione lyase activity
KS242_16505	COG2832	Protein of unknown function (DUF454)
KS242_16525	COG2030	dehydratase
KS242_16550	COG0366	Alpha amylase catalytic
KS242_16555	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_16575	COG0473	3-isopropylmalate dehydrogenase activity
KS242_16585	COG0492	ferredoxin-NADP+ reductase activity
KS242_16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS242_16595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS242_16600	COG2076	Multidrug Resistance protein
KS242_16605	COG2076	Multidrug Resistance protein
KS242_16615	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KS242_16620	COG1012	belongs to the aldehyde dehydrogenase family
KS242_16625	COG1510	regulation of RNA biosynthetic process
KS242_16630	COG2113	Glycine betaine
KS242_16635	COG3711	transcriptional antiterminator
KS242_16640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS242_16645	COG0716	FMN binding
KS242_16650	COG1051	belongs to the nudix hydrolase family
KS242_16670	COG2205	protein histidine kinase activity
KS242_16675	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KS242_16710	COG1414	Transcriptional regulator
KS242_16715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS242_16725	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_16730	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KS242_16735	COG3275	phosphorelay sensor kinase activity
KS242_16740	COG3279	Response regulator of the LytR AlgR family
KS242_16745	COG2223	nitrite transmembrane transporter activity
KS242_16750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS242_16770	COG1660	Displays ATPase and GTPase activities
KS242_16780	COG2207	Transcriptional regulator
KS242_16800	COG4335	DNA alkylation repair
KS242_16805	COG1280	lysine exporter protein (LysE YggA)
KS242_16835	COG3420	alginic acid biosynthetic process
KS242_16840	COG3011	Protein conserved in bacteria
KS242_16845	COG1316	TRANSCRIPTIONal
KS242_16850	COG3619	membrane
KS242_16855	COG3339	Conserved Protein
KS242_16860	COG1028	Short-chain dehydrogenase reductase Sdr
KS242_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS242_16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS242_16900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KS242_16905	COG4608	Belongs to the ABC transporter superfamily
KS242_16910	COG0444	Belongs to the ABC transporter superfamily
KS242_16925	COG0747	negative chemotaxis
KS242_16930	COG0577	efflux transmembrane transporter activity
KS242_16935	COG1136	(ABC) transporter
KS242_16940	COG0642	Histidine kinase
KS242_16945	COG0745	RESPONSE REGULATOR receiver
KS242_16965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS242_17010	COG0517	IMP dehydrogenase activity
KS242_17010	COG1125	glycine betaine transport
KS242_17020	COG1732	Glycine betaine
KS242_17025	COG1174	glycine betaine transport
KS242_17070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KS242_17075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KS242_17095	COG0772	Belongs to the SEDS family
KS242_17100	COG0534	Mate efflux family protein
KS242_17105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS242_17115	COG1486	melibiose metabolic process
KS242_17120	COG1609	Transcriptional regulator
KS242_17155	COG5002	protein histidine kinase activity
KS242_17160	COG0745	RESPONSE REGULATOR receiver
KS242_17165	COG0577	efflux transmembrane transporter activity
KS242_17170	COG1136	(ABC) transporter
KS242_17175	COG1113	amino acid transport
KS242_17185	COG0154	amidase activity
KS242_17190	COG0833	amino acid
KS242_17200	COG0768	penicillin binding
KS242_17205	COG1482	cell wall glycoprotein biosynthetic process
KS242_17210	COG2202	Pas domain
KS242_17210	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_17215	COG1309	transcriptional regulator
KS242_17220	COG1511	domain protein
KS242_17225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS242_17230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KS242_17235	COG4853	Protein conserved in bacteria
KS242_17240	COG4863	YycH protein
KS242_17245	COG5002	protein histidine kinase activity
KS242_17250	COG0745	RESPONSE REGULATOR receiver
KS242_17255	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KS242_17260	COG0305	Participates in initiation and elongation during chromosome replication
KS242_17265	COG0359	binds to the 23S rRNA
KS242_17270	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KS242_17275	COG4241	membrane
KS242_17280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS242_17285	COG0531	amino acid
KS242_17290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KS242_17300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KS242_17305	COG2814	Major facilitator Superfamily
KS242_17310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KS242_17315	COG0629	single-stranded DNA binding
KS242_17320	COG0360	Binds together with S18 to 16S ribosomal RNA
KS242_17325	COG0012	GTP binding
KS242_17330	COG4481	Protein conserved in bacteria
KS242_17335	COG0668	transmembrane transport
KS242_17340	COG3949	Membrane
KS242_17350	COG1475	DNA binding
KS242_17355	COG1192	Involved in chromosome partitioning
KS242_17360	COG1475	DNA binding
KS242_17365	COG0357	Ribosomal RNA small subunit methyltransferase G
KS242_17370	COG0445	tRNA wobble uridine modification
KS242_17375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KS242_17380	COG1847	R3H domain protein
KS242_17385	COG0706	membrane insertase activity
KS242_17390	COG0594	ribonuclease P activity
KS242_17395	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KS242_17460	COG1366	Belongs to the anti-sigma-factor antagonist family
KS242_17470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS242_17475	COG0662	Cupin 2, conserved barrel domain protein
KS242_17510	COG2323	membrane
KS242_17515	COG2323	membrane
KS242_17530	COG1086	Polysaccharide biosynthesis protein
KS242_17535	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KS242_17540	COG1216	Glycosyl transferase, family 2
KS242_17540	COG0463	Glycosyl transferase, family 2
KS242_17625	COG0739	heme binding
KS242_17695	COG4712	double-strand break repair protein
KS242_17700	COG0592	DNA-directed DNA polymerase activity
KS242_17795	COG0539	negative regulation of cytoplasmic translation
KS242_17805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KS242_17860	COG3764	Sortase (surface protein transpeptidase)
KS242_17925	COG0629	single-stranded DNA binding
KS242_17945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids