locus-tag	class	description
DSM104635_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DSM104635_00004	COG3850	Histidine kinase
DSM104635_00004	COG4999	Histidine kinase
DSM104635_00004	COG3437	response regulator, receiver
DSM104635_00004	COG2205	protein histidine kinase activity
DSM104635_00037	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DSM104635_00041	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DSM104635_00043	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSM104635_00051	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DSM104635_00054	COG1509	lysine 2,3-aminomutase activity
DSM104635_00057	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DSM104635_00058	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DSM104635_00065	COG4139	cobalamin transport
DSM104635_00066	COG1120	ATPase activity
DSM104635_00067	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104635_00090	COG0668	transmembrane transport
DSM104635_00092	COG0667	Aldo Keto reductase
DSM104635_00094	COG0833	amino acid
DSM104635_00096	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSM104635_00097	COG1522	sequence-specific DNA binding
DSM104635_00098	COG0686	Belongs to the AlaDH PNT family
DSM104635_00105	COG3811	Belongs to the UPF0386 family
DSM104635_00106	COG4638	Rieske (2fe-2S)
DSM104635_00108	COG2827	Endonuclease containing a URI domain
DSM104635_00110	COG0589	response to stress
DSM104635_00112	COG0542	response to heat
DSM104635_00114	COG0671	phosphoesterase, PA-phosphatase related
DSM104635_00115	COG1741	Belongs to the pirin family
DSM104635_00116	COG2226	methyltransferase
DSM104635_00117	COG1741	Belongs to the pirin family
DSM104635_00119	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSM104635_00120	COG0612	Peptidase, M16
DSM104635_00126	COG1024	Enoyl-CoA hydratase
DSM104635_00146	COG1024	Enoyl-CoA hydratase
DSM104635_00148	COG1024	Enoyl-CoA hydratase
DSM104635_00158	COG1021	2,3-dihydroxybenzoate-AMP ligase
DSM104635_00180	COG3307	-O-antigen
DSM104635_00182	COG1596	polysaccharide export
DSM104635_00184	COG3206	protein involved in exopolysaccharide biosynthesis
DSM104635_00184	COG0489	protein tyrosine kinase activity
DSM104635_00190	COG1596	polysaccharide export
DSM104635_00195	COG0367	asparagine synthase
DSM104635_00200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSM104635_00202	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104635_00205	COG2192	nodulation
DSM104635_00206	COG0463	Glycosyl transferase, family 2
DSM104635_00207	COG0297	glycogen (starch) synthase activity
DSM104635_00210	COG0297	glycogen (starch) synthase activity
DSM104635_00213	COG2244	polysaccharide biosynthetic process
DSM104635_00215	COG0367	asparagine synthase
DSM104635_00226	COG2201	protein-glutamate methylesterase activity
DSM104635_00228	COG1858	cytochrome C peroxidase
DSM104635_00230	COG4771	TonB-dependent receptor
DSM104635_00237	COG0582	viral genome integration into host DNA
DSM104635_00239	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSM104635_00240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DSM104635_00243	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DSM104635_00245	COG2962	Rard protein
DSM104635_00246	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DSM104635_00249	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DSM104635_00250	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104635_00253	COG3011	Protein conserved in bacteria
DSM104635_00255	COG2030	dehydratase
DSM104635_00261	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DSM104635_00267	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSM104635_00267	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSM104635_00270	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSM104635_00273	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104635_00282	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DSM104635_00283	COG0583	DNA-binding transcription factor activity
DSM104635_00284	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104635_00289	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104635_00290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSM104635_00293	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DSM104635_00294	COG1137	ATPase activity
DSM104635_00299	COG2133	pyrroloquinoline quinone binding
DSM104635_00303	COG1446	asparaginase
DSM104635_00305	COG0346	lactoylglutathione lyase activity
DSM104635_00307	COG0625	glutathione transferase activity
DSM104635_00311	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104635_00318	COG0481	GTPase activity
DSM104635_00326	COG5507	3-demethylubiquinone-9 3-methyltransferase
DSM104635_00327	COG4771	TonB-dependent receptor
DSM104635_00329	COG0339	signal peptide processing
DSM104635_00341	COG4771	TonB-dependent receptor
DSM104635_00348	COG0673	inositol 2-dehydrogenase activity
DSM104635_00349	COG0673	inositol 2-dehydrogenase activity
DSM104635_00351	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM104635_00352	COG3962	Belongs to the TPP enzyme family
DSM104635_00354	COG3718	enzyme involved in inositol metabolism
DSM104635_00355	COG2271	Major facilitator Superfamily
DSM104635_00356	COG0483	inositol monophosphate 1-phosphatase activity
DSM104635_00359	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DSM104635_00362	COG4774	siderophore transport
DSM104635_00363	COG2130	NADP-dependent
DSM104635_00364	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00369	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DSM104635_00374	COG1538	Outer membrane efflux protein
DSM104635_00377	COG1309	transcriptional regulator
DSM104635_00379	COG1309	transcriptional regulator
DSM104635_00381	COG4774	siderophore transport
DSM104635_00385	COG0009	L-threonylcarbamoyladenylate synthase
DSM104635_00388	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSM104635_00391	COG0457	Tetratricopeptide repeat
DSM104635_00391	COG0859	PFAM glycosyl transferase family 9
DSM104635_00392	COG3507	Belongs to the glycosyl hydrolase 43 family
DSM104635_00394	COG0859	PFAM glycosyl transferase family 9
DSM104635_00394	COG0457	Tetratricopeptide repeat
DSM104635_00403	COG0667	Aldo Keto reductase
DSM104635_00405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSM104635_00406	COG2204	response regulator
DSM104635_00407	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSM104635_00409	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSM104635_00410	COG1766	The M ring may be actively involved in energy transduction
DSM104635_00412	COG1749	Flagellar hook protein flgE
DSM104635_00413	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DSM104635_00417	COG0482	sulfurtransferase activity
DSM104635_00419	COG0183	Belongs to the thiolase family
DSM104635_00421	COG2895	sulfate adenylyltransferase (ATP) activity
DSM104635_00421	COG0529	Catalyzes the synthesis of activated sulfate
DSM104635_00422	COG0175	sulfate reduction
DSM104635_00429	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM104635_00430	COG0473	3-isopropylmalate dehydrogenase activity
DSM104635_00431	COG0066	3-isopropylmalate dehydratase activity
DSM104635_00432	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104635_00433	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104635_00436	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSM104635_00437	COG0129	dihydroxy-acid dehydratase activity
DSM104635_00438	COG0583	DNA-binding transcription factor activity
DSM104635_00439	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DSM104635_00442	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DSM104635_00444	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSM104635_00444	COG0140	phosphoribosyl-ATP diphosphatase activity
DSM104635_00445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM104635_00452	COG1864	DNA RNA non-specific endonuclease
DSM104635_00452	COG3591	Belongs to the peptidase S1B family
DSM104635_00464	COG2816	NAD+ diphosphatase activity
DSM104635_00465	COG0667	Aldo Keto reductase
DSM104635_00466	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00471	COG2124	cytochrome p450
DSM104635_00475	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00476	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DSM104635_00477	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104635_00478	COG0183	Belongs to the thiolase family
DSM104635_00479	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM104635_00479	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM104635_00481	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104635_00482	COG1024	Enoyl-CoA hydratase
DSM104635_00483	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00484	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DSM104635_00485	COG0045	succinate-CoA ligase (ADP-forming) activity
DSM104635_00486	COG2814	Major facilitator Superfamily
DSM104635_00488	COG1063	alcohol dehydrogenase
DSM104635_00489	COG0583	DNA-binding transcription factor activity
DSM104635_00490	COG2814	Major facilitator Superfamily
DSM104635_00491	COG0431	NADPH-dependent FMN reductase
DSM104635_00496	COG1024	Enoyl-CoA hydratase
DSM104635_00500	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00501	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00503	COG1024	Enoyl-CoA hydratase
DSM104635_00505	COG3618	amidohydrolase
DSM104635_00508	COG1012	belongs to the aldehyde dehydrogenase family
DSM104635_00509	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DSM104635_00510	COG2124	cytochrome p450
DSM104635_00511	COG5507	3-demethylubiquinone-9 3-methyltransferase
DSM104635_00513	COG0667	Aldo Keto reductase
DSM104635_00514	COG4221	oxidoreductase activity
DSM104635_00516	COG2267	carboxylic ester hydrolase activity
DSM104635_00519	COG2197	response regulator
DSM104635_00520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104635_00527	COG2814	Major facilitator Superfamily
DSM104635_00532	COG1335	isochorismatase
DSM104635_00533	COG0667	Aldo Keto reductase
DSM104635_00535	COG0656	L-ascorbic acid biosynthetic process
DSM104635_00537	COG0583	DNA-binding transcription factor activity
DSM104635_00538	COG1917	Cupin 2, conserved barrel domain protein
DSM104635_00538	COG4977	sequence-specific DNA binding
DSM104635_00539	COG1741	Belongs to the pirin family
DSM104635_00540	COG0655	NAD(P)H dehydrogenase (quinone) activity
DSM104635_00543	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DSM104635_00548	COG1476	TRANSCRIPTIONal
DSM104635_00554	COG2204	response regulator
DSM104635_00555	COG4191	Histidine kinase
DSM104635_00556	COG1301	dicarboxylic acid transport
DSM104635_00559	COG4771	TonB-dependent receptor
DSM104635_00560	COG2124	cytochrome p450
DSM104635_00562	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104635_00563	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00563	COG3321	synthase
DSM104635_00563	COG0604	alcohol dehydrogenase
DSM104635_00567	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104635_00569	COG2207	Transcriptional regulator
DSM104635_00570	COG2816	NAD+ diphosphatase activity
DSM104635_00571	COG1024	Enoyl-CoA hydratase
DSM104635_00572	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00573	COG1309	transcriptional regulator
DSM104635_00576	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104635_00577	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104635_00579	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DSM104635_00580	COG0022	dehydrogenase e1 component
DSM104635_00581	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104635_00582	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DSM104635_00587	COG1024	Enoyl-CoA hydratase
DSM104635_00588	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00589	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00598	COG4771	TonB-dependent receptor
DSM104635_00599	COG0066	3-isopropylmalate dehydratase activity
DSM104635_00600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104635_00601	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104635_00602	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104635_00603	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104635_00608	COG0431	NADPH-dependent FMN reductase
DSM104635_00609	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00612	COG1902	pentaerythritol trinitrate reductase activity
DSM104635_00615	COG4771	TonB-dependent receptor
DSM104635_00616	COG0633	Ferredoxin
DSM104635_00620	COG1846	Transcriptional regulator
DSM104635_00622	COG4771	TonB-dependent receptor
DSM104635_00623	COG0657	acetylesterase activity
DSM104635_00627	COG2814	Major facilitator Superfamily
DSM104635_00628	COG0129	dihydroxy-acid dehydratase activity
DSM104635_00630	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSM104635_00632	COG2186	Transcriptional regulator
DSM104635_00633	COG2084	Dehydrogenase
DSM104635_00635	COG4771	TonB-dependent receptor
DSM104635_00638	COG1522	sequence-specific DNA binding
DSM104635_00651	COG3437	response regulator, receiver
DSM104635_00651	COG4999	Histidine kinase
DSM104635_00651	COG3850	Histidine kinase
DSM104635_00651	COG2205	protein histidine kinase activity
DSM104635_00652	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSM104635_00653	COG2151	metal-sulfur cluster biosynthetic enzyme
DSM104635_00654	COG3396	Phenylacetate-CoA oxygenase
DSM104635_00655	COG3460	Phenylacetate-CoA oxygenase
DSM104635_00657	COG3396	Phenylacetate-CoA oxygenase
DSM104635_00658	COG2050	protein possibly involved in aromatic compounds catabolism
DSM104635_00659	COG1024	Enoyl-CoA hydratase
DSM104635_00660	COG2030	dehydratase
DSM104635_00660	COG1012	belongs to the aldehyde dehydrogenase family
DSM104635_00661	COG1448	Aminotransferase
DSM104635_00662	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104635_00663	COG0022	dehydrogenase e1 component
DSM104635_00665	COG4251	negative regulation of phosphorylation
DSM104635_00665	COG5001	Diguanylate cyclase
DSM104635_00665	COG3706	GGDEF domain
DSM104635_00665	COG2203	Gaf domain
DSM104635_00668	COG0784	Response regulator, receiver
DSM104635_00675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DSM104635_00676	COG5487	UPF0391 membrane protein
DSM104635_00679	COG1024	Enoyl-CoA hydratase
DSM104635_00682	COG2197	response regulator
DSM104635_00685	COG0602	queuosine metabolic process
DSM104635_00687	COG2197	response regulator
DSM104635_00688	COG1741	Belongs to the pirin family
DSM104635_00692	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00693	COG2814	Major facilitator Superfamily
DSM104635_00699	COG0714	Associated with various cellular activities
DSM104635_00703	COG0494	nUDIX hydrolase
DSM104635_00704	COG1917	Cupin 2, conserved barrel domain protein
DSM104635_00704	COG4977	sequence-specific DNA binding
DSM104635_00705	COG0346	lactoylglutathione lyase activity
DSM104635_00710	COG0617	tRNA 3'-terminal CCA addition
DSM104635_00713	COG0408	coproporphyrinogen oxidase activity
DSM104635_00714	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DSM104635_00716	COG2857	Cytochrome c1
DSM104635_00716	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSM104635_00717	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSM104635_00717	COG2857	Cytochrome c1
DSM104635_00722	COG0740	serine-type endopeptidase activity
DSM104635_00723	COG1297	OPT oligopeptide transporter protein
DSM104635_00725	COG0352	thiamine-phosphate diphosphorylase activity
DSM104635_00727	COG3588	fructose-bisphosphate aldolase
DSM104635_00737	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSM104635_00741	COG0217	transcriptional regulatory protein
DSM104635_00747	COG2824	Alkylphosphonate utilization operon protein PhnA
DSM104635_00748	COG1968	undecaprenyl-diphosphatase activity
DSM104635_00752	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSM104635_00753	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSM104635_00761	COG0438	transferase activity, transferring glycosyl groups
DSM104635_00763	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DSM104635_00766	COG3485	protocatechuate 3,4-dioxygenase
DSM104635_00767	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DSM104635_00768	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DSM104635_00769	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DSM104635_00770	COG0072	phenylalanine-tRNA ligase activity
DSM104635_00770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104635_00778	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104635_00779	COG0825	malonyl-CoA metabolic process
DSM104635_00785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104635_00786	COG2076	Multidrug Resistance protein
DSM104635_00790	COG4974	Belongs to the 'phage' integrase family
DSM104635_00795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DSM104635_00796	COG1253	flavin adenine dinucleotide binding
DSM104635_00803	COG0405	Gamma-glutamyltransferase
DSM104635_00804	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSM104635_00805	COG0745	RESPONSE REGULATOR receiver
DSM104635_00807	COG0475	glutathione-regulated potassium exporter activity
DSM104635_00807	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSM104635_00809	COG0596	Alpha beta hydrolase
DSM104635_00810	COG0783	Belongs to the Dps family
DSM104635_00811	COG0076	glutamate decarboxylase activity
DSM104635_00814	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104635_00815	COG2373	Large extracellular alpha-helical protein
DSM104635_00817	COG4953	penicillin-binding protein 1C
DSM104635_00831	COG2205	protein histidine kinase activity
DSM104635_00833	COG1404	Belongs to the peptidase S8 family
DSM104635_00838	COG4172	Belongs to the ABC transporter superfamily
DSM104635_00840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSM104635_00844	COG0545	Peptidyl-prolyl cis-trans isomerase
DSM104635_00852	COG0739	heme binding
DSM104635_00858	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DSM104635_00861	COG0438	transferase activity, transferring glycosyl groups
DSM104635_00866	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DSM104635_00867	COG1960	acyl-CoA dehydrogenase activity
DSM104635_00868	COG2244	polysaccharide biosynthetic process
DSM104635_00869	COG1215	transferase activity, transferring glycosyl groups
DSM104635_00870	COG3206	protein involved in exopolysaccharide biosynthesis
DSM104635_00870	COG0489	protein tyrosine kinase activity
DSM104635_00871	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSM104635_00872	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104635_00873	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DSM104635_00877	COG4310	Domain of unknown function (DUF2172)
DSM104635_00887	COG3206	protein involved in exopolysaccharide biosynthesis
DSM104635_00887	COG0489	protein tyrosine kinase activity
DSM104635_00888	COG1596	polysaccharide export
DSM104635_00899	COG1073	alpha beta
DSM104635_00901	COG3590	peptidase
DSM104635_00903	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104635_00908	COG0745	RESPONSE REGULATOR receiver
DSM104635_00916	COG2267	carboxylic ester hydrolase activity
DSM104635_00917	COG0183	Belongs to the thiolase family
DSM104635_00924	COG4106	trans-aconitate 2-methyltransferase activity
DSM104635_00925	COG4152	abc transporter atp-binding protein
DSM104635_00931	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DSM104635_00933	COG5001	Diguanylate cyclase
DSM104635_00933	COG3447	MASE1 domain protein
DSM104635_00933	COG5002	protein histidine kinase activity
DSM104635_00941	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104635_00945	COG3321	synthase
DSM104635_00945	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_00945	COG0604	alcohol dehydrogenase
DSM104635_00952	COG4651	solute:proton antiporter activity
DSM104635_00952	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSM104635_00955	COG2204	response regulator
DSM104635_00960	COG3750	Belongs to the UPF0335 family
DSM104635_00962	COG0457	Tetratricopeptide repeat
DSM104635_00963	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DSM104635_00965	COG2814	Major facilitator Superfamily
DSM104635_00966	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSM104635_00968	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DSM104635_00968	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104635_00971	COG0483	inositol monophosphate 1-phosphatase activity
DSM104635_00974	COG0412	Dienelactone hydrolase
DSM104635_00977	COG2814	Major facilitator Superfamily
DSM104635_00978	COG0012	GTP binding
DSM104635_00982	COG0193	aminoacyl-tRNA hydrolase activity
DSM104635_00985	COG3158	transport of potassium into the cell
DSM104635_00986	COG2205	protein histidine kinase activity
DSM104635_00997	COG2813	Specifically methylates the guanine in position
DSM104635_01005	COG2175	clavaminate synthase activity
DSM104635_01010	COG0463	Glycosyl transferase, family 2
DSM104635_01011	COG0745	RESPONSE REGULATOR receiver
DSM104635_01012	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM104635_01020	COG2201	protein-glutamate methylesterase activity
DSM104635_01024	COG1201	RNA secondary structure unwinding
DSM104635_01026	COG0513	Belongs to the DEAD box helicase family
DSM104635_01027	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DSM104635_01031	COG0730	response to heat
DSM104635_01035	COG0789	Transcriptional regulator
DSM104635_01036	COG1960	acyl-CoA dehydrogenase activity
DSM104635_01037	COG2852	Protein conserved in bacteria
DSM104635_01039	COG0183	Belongs to the thiolase family
DSM104635_01041	COG1024	Enoyl-CoA hydratase
DSM104635_01041	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104635_01044	COG1902	pentaerythritol trinitrate reductase activity
DSM104635_01047	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DSM104635_01052	COG0513	Belongs to the DEAD box helicase family
DSM104635_01063	COG3047	cAMP biosynthetic process
DSM104635_01063	COG2885	chlorophyll binding
DSM104635_01075	COG0183	Belongs to the thiolase family
DSM104635_01080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DSM104635_01084	COG1024	Enoyl-CoA hydratase
DSM104635_01085	COG1272	protein, Hemolysin III
DSM104635_01089	COG0735	belongs to the Fur family
DSM104635_01091	COG2827	Endonuclease containing a URI domain
DSM104635_01092	COG2304	oxidoreductase activity
DSM104635_01098	COG2986	histidine ammonia-lyase
DSM104635_01099	COG0124	histidyl-tRNA synthetase
DSM104635_01100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DSM104635_01105	COG0459	protein refolding
DSM104635_01106	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSM104635_01108	COG1309	transcriptional regulator
DSM104635_01109	COG0386	Belongs to the glutathione peroxidase family
DSM104635_01110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSM104635_01113	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DSM104635_01115	COG0612	Peptidase, M16
DSM104635_01116	COG0612	Peptidase, M16
DSM104635_01120	COG1690	Belongs to the RtcB family
DSM104635_01123	COG1611	Belongs to the LOG family
DSM104635_01124	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSM104635_01126	COG0346	lactoylglutathione lyase activity
DSM104635_01127	COG0494	nUDIX hydrolase
DSM104635_01128	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSM104635_01129	COG0352	thiamine-phosphate diphosphorylase activity
DSM104635_01129	COG0351	phosphomethylpyrimidine kinase
DSM104635_01131	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DSM104635_01133	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104635_01136	COG3621	Patatin-like phospholipase
DSM104635_01137	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSM104635_01142	COG2982	Protein involved in outer membrane biogenesis
DSM104635_01146	COG0564	pseudouridine synthase activity
DSM104635_01151	COG3739	integral membrane protein
DSM104635_01152	COG2852	Protein conserved in bacteria
DSM104635_01160	COG0215	cysteine-tRNA ligase activity
DSM104635_01161	COG0302	gtp cyclohydrolase
DSM104635_01170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSM104635_01171	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSM104635_01172	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSM104635_01173	COG1017	nitric oxide dioxygenase activity
DSM104635_01173	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSM104635_01180	COG0154	amidase activity
DSM104635_01181	COG2226	methyltransferase
DSM104635_01182	COG2226	methyltransferase
DSM104635_01184	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DSM104635_01190	COG2197	response regulator
DSM104635_01196	COG1322	Protein conserved in bacteria
DSM104635_01200	COG2816	NAD+ diphosphatase activity
DSM104635_01208	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSM104635_01212	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSM104635_01212	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSM104635_01213	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DSM104635_01214	COG0604	alcohol dehydrogenase
DSM104635_01218	COG1794	racemase activity, acting on amino acids and derivatives
DSM104635_01219	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104635_01225	COG0006	proline dipeptidase activity
DSM104635_01231	COG2259	Doxx family
DSM104635_01232	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSM104635_01235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DSM104635_01237	COG0784	Response regulator, receiver
DSM104635_01237	COG2205	protein histidine kinase activity
DSM104635_01244	COG0242	peptide deformylase activity
DSM104635_01245	COG1295	ribonuclease BN
DSM104635_01246	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM104635_01248	COG0101	tRNA pseudouridine synthase activity
DSM104635_01250	COG2311	Membrane
DSM104635_01252	COG2171	N-acyltransferase activity
DSM104635_01256	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSM104635_01259	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DSM104635_01261	COG4191	Histidine kinase
DSM104635_01263	COG0405	Gamma-glutamyltransferase
DSM104635_01264	COG3191	aminopeptidase activity
DSM104635_01275	COG0742	ribosomal rna small subunit methyltransferase
DSM104635_01276	COG0861	Integral membrane protein TerC family
DSM104635_01277	COG1187	pseudouridine synthase activity
DSM104635_01279	COG0590	tRNA wobble adenosine to inosine editing
DSM104635_01280	COG2030	dehydratase
DSM104635_01281	COG0196	riboflavin kinase activity
DSM104635_01282	COG0745	RESPONSE REGULATOR receiver
DSM104635_01283	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01286	COG0572	uridine kinase
DSM104635_01288	COG3300	MHYT domain
DSM104635_01288	COG5001	Diguanylate cyclase
DSM104635_01291	COG3655	Transcriptional regulator
DSM104635_01297	COG0598	Magnesium transport protein CorA
DSM104635_01298	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DSM104635_01300	COG0151	Belongs to the GarS family
DSM104635_01301	COG0308	aminopeptidase N
DSM104635_01303	COG1570	exodeoxyribonuclease VII activity
DSM104635_01310	COG1663	tetraacyldisaccharide 4'-kinase activity
DSM104635_01311	COG1519	Transferase
DSM104635_01315	COG1132	(ABC) transporter
DSM104635_01318	COG0312	modulator of DNA gyrase
DSM104635_01322	COG2264	protein methyltransferase activity
DSM104635_01325	COG0640	Transcriptional regulator
DSM104635_01329	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSM104635_01331	COG5265	(ABC) transporter
DSM104635_01333	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSM104635_01340	COG0312	modulator of DNA gyrase
DSM104635_01343	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSM104635_01344	COG0109	protoheme IX farnesyltransferase activity
DSM104635_01346	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DSM104635_01349	COG3346	SURF1 family
DSM104635_01350	COG0612	Peptidase, M16
DSM104635_01351	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM104635_01354	COG0330	HflC and HflK could
DSM104635_01358	COG0328	RNA-DNA hybrid ribonuclease activity
DSM104635_01360	COG0572	uridine kinase
DSM104635_01361	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSM104635_01363	COG0018	arginyl-trna synthetase
DSM104635_01365	COG2862	Uncharacterized protein family, UPF0114
DSM104635_01372	COG0494	nUDIX hydrolase
DSM104635_01375	COG0277	FAD linked oxidase domain protein
DSM104635_01377	COG2353	YceI-like domain
DSM104635_01379	COG1960	acyl-CoA dehydrogenase activity
DSM104635_01381	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104635_01388	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01394	COG1793	dna ligase
DSM104635_01396	COG1131	(ABC) transporter
DSM104635_01397	COG0842	Transport permease protein
DSM104635_01405	COG1722	exodeoxyribonuclease VII activity
DSM104635_01406	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104635_01415	COG1024	Enoyl-CoA hydratase
DSM104635_01423	COG3609	addiction module antidote protein, CC2985 family
DSM104635_01426	COG3483	tryptophan 2,3-dioxygenase activity
DSM104635_01428	COG0778	Nitroreductase
DSM104635_01430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104635_01431	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSM104635_01437	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DSM104635_01440	COG0537	adenosine 5'-monophosphoramidase activity
DSM104635_01447	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DSM104635_01449	COG1546	Belongs to the CinA family
DSM104635_01449	COG1058	Belongs to the CinA family
DSM104635_01451	COG0456	acetyltransferase
DSM104635_01453	COG1063	alcohol dehydrogenase
DSM104635_01455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104635_01459	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01463	COG0494	nUDIX hydrolase
DSM104635_01464	COG1045	serine acetyltransferase
DSM104635_01466	COG1462	curli production assembly transport component CsgG
DSM104635_01470	COG0517	IMP dehydrogenase activity
DSM104635_01477	COG0438	transferase activity, transferring glycosyl groups
DSM104635_01481	COG3275	phosphorelay sensor kinase activity
DSM104635_01482	COG3279	Response regulator of the LytR AlgR family
DSM104635_01483	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01484	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSM104635_01485	COG0730	response to heat
DSM104635_01489	COG1960	acyl-CoA dehydrogenase activity
DSM104635_01494	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM104635_01498	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01504	COG1960	acyl-CoA dehydrogenase activity
DSM104635_01508	COG1573	uracil-dna glycosylase
DSM104635_01513	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM104635_01516	COG0546	phosphoglycolate phosphatase activity
DSM104635_01517	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSM104635_01518	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DSM104635_01525	COG0616	signal peptide processing
DSM104635_01528	COG0047	phosphoribosylformylglycinamidine synthase activity
DSM104635_01529	COG2124	cytochrome p450
DSM104635_01532	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSM104635_01536	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSM104635_01537	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DSM104635_01542	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DSM104635_01544	COG2271	Major facilitator Superfamily
DSM104635_01545	COG2003	Belongs to the UPF0758 family
DSM104635_01546	COG0024	Methionine aminopeptidase
DSM104635_01550	COG0784	Response regulator, receiver
DSM104635_01551	COG1940	carbohydrate kinase activity
DSM104635_01552	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSM104635_01557	COG0557	exoribonuclease II activity
DSM104635_01558	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSM104635_01558	COG1754	DNA topoisomerase type I activity
DSM104635_01560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSM104635_01560	COG0758	DNA mediated transformation
DSM104635_01561	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DSM104635_01566	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DSM104635_01568	COG0540	Belongs to the ATCase OTCase family
DSM104635_01572	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSM104635_01575	COG0154	amidase activity
DSM104635_01584	COG3108	Peptidase M15
DSM104635_01588	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DSM104635_01590	COG2885	chlorophyll binding
DSM104635_01595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSM104635_01599	COG0625	glutathione transferase activity
DSM104635_01604	COG2308	Evidence 4 Homologs of previously reported genes of
DSM104635_01605	COG0848	biopolymer transport protein
DSM104635_01613	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSM104635_01615	COG2723	6-phospho-beta-galactosidase activity
DSM104635_01617	COG1609	Transcriptional regulator
DSM104635_01621	COG1175	transmembrane transport
DSM104635_01622	COG0395	ABC-type sugar transport system, permease component
DSM104635_01626	COG3119	arylsulfatase activity
DSM104635_01629	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSM104635_01634	COG0714	Associated with various cellular activities
DSM104635_01639	COG0492	ferredoxin-NADP+ reductase activity
DSM104635_01641	COG0625	glutathione transferase activity
DSM104635_01642	COG0730	response to heat
DSM104635_01643	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSM104635_01645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DSM104635_01647	COG5328	Belongs to the UPF0262 family
DSM104635_01649	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSM104635_01650	COG0300	oxidoreductase activity
DSM104635_01651	COG0424	maF-like protein
DSM104635_01652	COG1530	ribonuclease E activity
DSM104635_01653	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DSM104635_01660	COG0778	Nitroreductase
DSM104635_01662	COG0316	Belongs to the HesB IscA family
DSM104635_01663	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DSM104635_01665	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104635_01666	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DSM104635_01667	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DSM104635_01668	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSM104635_01669	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSM104635_01670	COG0805	protein transport
DSM104635_01671	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSM104635_01683	COG0439	Biotin carboxylase
DSM104635_01684	COG0511	ligase activity, forming carbon-carbon bonds
DSM104635_01685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DSM104635_01688	COG2022	thiamine diphosphate biosynthetic process
DSM104635_01690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DSM104635_01692	COG0534	Mate efflux family protein
DSM104635_01694	COG2130	NADP-dependent
DSM104635_01695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104635_01698	COG2070	2-Nitropropane dioxygenase
DSM104635_01701	COG5265	(ABC) transporter
DSM104635_01723	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104635_01725	COG0525	valine-tRNA ligase activity
DSM104635_01728	COG2272	Belongs to the type-B carboxylesterase lipase family
DSM104635_01734	COG4783	chaperone-mediated protein folding
DSM104635_01744	COG0784	Response regulator, receiver
DSM104635_01744	COG2205	protein histidine kinase activity
DSM104635_01744	COG2198	Histidine kinase
DSM104635_01746	COG0113	porphobilinogen synthase activity
DSM104635_01749	COG0300	oxidoreductase activity
DSM104635_01750	COG3250	beta-galactosidase activity
DSM104635_01751	COG4952	isomerase
DSM104635_01752	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01752	COG3347	Dehydrogenase
DSM104635_01754	COG1304	FMN binding
DSM104635_01757	COG3940	Belongs to the glycosyl hydrolase 43 family
DSM104635_01759	COG0277	FAD linked oxidase domain protein
DSM104635_01763	COG1304	FMN binding
DSM104635_01764	COG0583	DNA-binding transcription factor activity
DSM104635_01766	COG2814	Major facilitator Superfamily
DSM104635_01773	COG1802	Transcriptional regulator
DSM104635_01774	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104635_01778	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_01779	COG3345	alpha-galactosidase
DSM104635_01783	COG2771	luxR family
DSM104635_01786	COG4962	Type ii secretion system protein e
DSM104635_01787	COG3838	Conjugal transfer protein Trbc
DSM104635_01789	COG3451	type IV secretory pathway VirB4
DSM104635_01794	COG2948	multi-organism process
DSM104635_01796	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
DSM104635_01797	COG1431	PFAM Stem cell self-renewal protein Piwi
DSM104635_01801	COG0758	DNA mediated transformation
DSM104635_01806	COG4974	Belongs to the 'phage' integrase family
DSM104635_01808	COG0189	ligase activity
DSM104635_01808	COG2918	glutathione biosynthetic process
DSM104635_01812	COG2022	thiamine diphosphate biosynthetic process
DSM104635_01812	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104635_01819	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSM104635_01820	COG0235	Class ii aldolase
DSM104635_01822	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104635_01823	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSM104635_01824	COG3474	cytochrome
DSM104635_01825	COG1404	Belongs to the peptidase S8 family
DSM104635_01826	COG1595	DNA-templated transcription, initiation
DSM104635_01832	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104635_01833	COG0456	acetyltransferase
DSM104635_01835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM104635_01838	COG3360	Dodecin
DSM104635_01839	COG4206	TonB-dependent receptor
DSM104635_01841	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSM104635_01844	COG0051	transcription antitermination factor activity, RNA binding
DSM104635_01845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DSM104635_01847	COG0089	rRNA binding
DSM104635_01848	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSM104635_01849	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSM104635_01850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DSM104635_01851	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DSM104635_01853	COG0255	Belongs to the universal ribosomal protein uL29 family
DSM104635_01854	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSM104635_01855	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DSM104635_01856	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DSM104635_01857	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSM104635_01858	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DSM104635_01859	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DSM104635_01860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSM104635_01861	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DSM104635_01862	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSM104635_01863	COG1841	ribosomal large subunit assembly
DSM104635_01864	COG0200	Binds to the 23S rRNA
DSM104635_01865	COG0201	protein transport
DSM104635_01866	COG0563	adenylate kinase activity
DSM104635_01868	COG1733	regulation of RNA biosynthetic process
DSM104635_01870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSM104635_01872	COG0203	ribosomal protein L17
DSM104635_01876	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104635_01878	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSM104635_01879	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSM104635_01883	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DSM104635_01888	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104635_01890	COG0456	acetyltransferase
DSM104635_01894	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DSM104635_01898	COG1192	Involved in chromosome partitioning
DSM104635_01900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DSM104635_01902	COG0189	ligase activity
DSM104635_01903	COG0302	gtp cyclohydrolase
DSM104635_01904	COG0471	metal ion transport
DSM104635_01909	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DSM104635_01912	COG1040	competence protein
DSM104635_01914	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSM104635_01917	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104635_01918	COG0527	aspartate kinase activity
DSM104635_01921	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DSM104635_01923	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DSM104635_01924	COG2890	protein-(glutamine-N5) methyltransferase activity
DSM104635_01926	COG2945	thiolester hydrolase activity
DSM104635_01927	COG1959	2 iron, 2 sulfur cluster binding
DSM104635_01928	COG1104	cysteine desulfurase activity
DSM104635_01929	COG0719	Fe-S assembly protein
DSM104635_01931	COG0396	ATPase activity
DSM104635_01932	COG0719	Fe-S assembly protein
DSM104635_01933	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DSM104635_01935	COG0316	Belongs to the HesB IscA family
DSM104635_01937	COG1024	Enoyl-CoA hydratase
DSM104635_01939	COG1012	belongs to the aldehyde dehydrogenase family
DSM104635_01941	COG0513	Belongs to the DEAD box helicase family
DSM104635_01942	COG0187	DNA topoisomerase II activity
DSM104635_01945	COG2378	regulation of single-species biofilm formation
DSM104635_01946	COG0174	glutamine synthetase
DSM104635_01947	COG0347	Belongs to the P(II) protein family
DSM104635_01948	COG0406	alpha-ribazole phosphatase activity
DSM104635_01949	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSM104635_01949	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSM104635_01952	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSM104635_01954	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSM104635_01961	COG2897	thiosulfate sulfurtransferase activity
DSM104635_01962	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSM104635_01963	COG0463	Glycosyl transferase, family 2
DSM104635_01964	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DSM104635_01966	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DSM104635_01968	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104635_01971	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DSM104635_01973	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DSM104635_01974	COG1686	Belongs to the peptidase S11 family
DSM104635_01975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSM104635_01977	COG0084	hydrolase, TatD family'
DSM104635_01980	COG3956	TIGRFAM MazG family protein
DSM104635_01984	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM104635_01985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSM104635_01986	COG1923	regulation of RNA biosynthetic process
DSM104635_01988	COG2204	response regulator
DSM104635_01989	COG5000	phosphorelay sensor kinase activity
DSM104635_01990	COG2204	response regulator
DSM104635_01991	COG3852	Histidine kinase
DSM104635_01992	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSM104635_01995	COG1546	Belongs to the CinA family
DSM104635_01995	COG1058	Belongs to the CinA family
DSM104635_01998	COG0204	Acyl-transferase
DSM104635_01998	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104635_02001	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104635_02002	COG2095	MarC family integral membrane protein
DSM104635_02006	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104635_02011	COG0022	dehydrogenase e1 component
DSM104635_02011	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104635_02014	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DSM104635_02016	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DSM104635_02018	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSM104635_02020	COG0659	secondary active sulfate transmembrane transporter activity
DSM104635_02023	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DSM104635_02024	COG0517	IMP dehydrogenase activity
DSM104635_02032	COG0149	triose-phosphate isomerase activity
DSM104635_02034	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DSM104635_02037	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DSM104635_02038	COG0134	indole-3-glycerol-phosphate synthase activity
DSM104635_02039	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSM104635_02041	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104635_02042	COG0372	Belongs to the citrate synthase family
DSM104635_02043	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104635_02044	COG3494	Protein of unknown function (DUF1009)
DSM104635_02047	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104635_02050	COG0750	zinc metalloprotease
DSM104635_02051	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DSM104635_02052	COG0575	Belongs to the CDS family
DSM104635_02053	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSM104635_02054	COG0233	cytoplasmic translational termination
DSM104635_02055	COG0528	UMP kinase activity
DSM104635_02059	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DSM104635_02062	COG1136	(ABC) transporter
DSM104635_02063	COG4591	ABC-type transport system involved in lipoprotein release permease component
DSM104635_02066	COG0346	lactoylglutathione lyase activity
DSM104635_02068	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DSM104635_02070	COG1007	ATP synthesis coupled electron transport
DSM104635_02075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104635_02077	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSM104635_02080	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DSM104635_02082	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DSM104635_02086	COG0649	NAD binding
DSM104635_02089	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104635_02090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104635_02094	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DSM104635_02096	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104635_02102	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSM104635_02110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSM104635_02110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DSM104635_02111	COG1494	fructose-1,6-bisphosphatase
DSM104635_02112	COG0436	Aminotransferase
DSM104635_02114	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSM104635_02118	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSM104635_02119	COG1612	heme a metabolic process
DSM104635_02122	COG1877	trehalose-phosphatase activity
DSM104635_02123	COG3387	PFAM Glycoside hydrolase 15-related
DSM104635_02124	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DSM104635_02127	COG0776	regulation of translation
DSM104635_02128	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSM104635_02129	COG0416	fatty acid biosynthetic process
DSM104635_02133	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSM104635_02135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DSM104635_02137	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DSM104635_02138	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM104635_02138	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM104635_02140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104635_02140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104635_02141	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSM104635_02142	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM104635_02143	COG4957	zinc ion binding
DSM104635_02145	COG0156	8-amino-7-oxononanoate synthase activity
DSM104635_02146	COG0113	porphobilinogen synthase activity
DSM104635_02151	COG2084	Dehydrogenase
DSM104635_02153	COG1360	Flagellar Motor Protein
DSM104635_02156	COG3590	peptidase
DSM104635_02160	COG0501	Belongs to the peptidase M48B family
DSM104635_02161	COG1704	LemA family
DSM104635_02162	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DSM104635_02163	COG1381	Involved in DNA repair and RecF pathway recombination
DSM104635_02165	COG0571	ribonuclease III activity
DSM104635_02166	COG0681	Belongs to the peptidase S26 family
DSM104635_02167	COG0736	holo-[acyl-carrier-protein] synthase activity
DSM104635_02168	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DSM104635_02169	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSM104635_02172	COG1758	RNA polymerase activity
DSM104635_02173	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DSM104635_02174	COG1573	uracil-dna glycosylase
DSM104635_02175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DSM104635_02176	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104635_02179	COG1643	Atp-dependent helicase
DSM104635_02181	COG0343	queuine tRNA-ribosyltransferase activity
DSM104635_02182	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DSM104635_02186	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DSM104635_02187	COG2032	superoxide dismutase activity
DSM104635_02189	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104635_02190	COG0629	single-stranded DNA binding
DSM104635_02191	COG3384	dioxygenase
DSM104635_02193	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSM104635_02198	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DSM104635_02199	COG1505	serine-type exopeptidase activity
DSM104635_02202	COG2205	protein histidine kinase activity
DSM104635_02202	COG2202	Pas domain
DSM104635_02203	COG0579	oxidoreductase
DSM104635_02204	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSM104635_02205	COG0228	four-way junction DNA binding
DSM104635_02206	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DSM104635_02208	COG0336	Belongs to the RNA methyltransferase TrmD family
DSM104635_02211	COG0335	large ribosomal subunit rRNA binding
DSM104635_02213	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM104635_02214	COG0552	protein localization to endoplasmic reticulum
DSM104635_02218	COG2917	probably involved in intracellular septation
DSM104635_02220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104635_02222	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSM104635_02223	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSM104635_02224	COG4133	protoheme IX ABC transporter activity
DSM104635_02227	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DSM104635_02234	COG0670	Belongs to the BI1 family
DSM104635_02235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSM104635_02239	COG1999	signal sequence binding
DSM104635_02244	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DSM104635_02247	COG3876	Protein conserved in bacteria
DSM104635_02249	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSM104635_02252	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104635_02257	COG1309	transcriptional regulator
DSM104635_02261	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSM104635_02262	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM104635_02264	COG1530	ribonuclease E activity
DSM104635_02265	COG4783	chaperone-mediated protein folding
DSM104635_02269	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSM104635_02270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSM104635_02273	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104635_02279	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSM104635_02283	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSM104635_02286	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DSM104635_02289	COG0248	Ppx GppA phosphatase
DSM104635_02290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DSM104635_02293	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSM104635_02294	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSM104635_02300	COG0105	UTP biosynthetic process
DSM104635_02306	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSM104635_02310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104635_02311	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DSM104635_02312	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSM104635_02313	COG2353	YceI-like domain
DSM104635_02314	COG0194	GDP metabolic process
DSM104635_02315	COG1561	YicC-like family, N-terminal region
DSM104635_02317	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSM104635_02318	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSM104635_02319	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSM104635_02323	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DSM104635_02329	COG0360	Binds together with S18 to 16S ribosomal RNA
DSM104635_02330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DSM104635_02331	COG0359	binds to the 23S rRNA
DSM104635_02334	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DSM104635_02336	COG1127	ABC transporter
DSM104635_02338	COG0386	Belongs to the glutathione peroxidase family
DSM104635_02342	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSM104635_02343	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_02345	COG2081	HI0933 family
DSM104635_02347	COG1160	GTP binding
DSM104635_02350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSM104635_02352	COG1595	DNA-templated transcription, initiation
DSM104635_02354	COG0640	Transcriptional regulator
DSM104635_02362	COG1393	Belongs to the ArsC family
DSM104635_02371	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSM104635_02371	COG0519	Catalyzes the synthesis of GMP from XMP
DSM104635_02373	COG2818	Glycosylase
DSM104635_02375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DSM104635_02379	COG3657	addiction module killer protein
DSM104635_02380	COG3724	N-succinylarginine dihydrolase activity
DSM104635_02381	COG1012	belongs to the aldehyde dehydrogenase family
DSM104635_02387	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DSM104635_02399	COG0514	ATP-dependent DNA helicase (RecQ)
DSM104635_02402	COG3743	rRNA binding
DSM104635_02402	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSM104635_02403	COG2885	chlorophyll binding
DSM104635_02405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM104635_02406	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DSM104635_02406	COG0116	Belongs to the methyltransferase superfamily
DSM104635_02407	COG1024	Enoyl-CoA hydratase
DSM104635_02408	COG0587	DNA-directed DNA polymerase activity
DSM104635_02411	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM104635_02415	COG1960	acyl-CoA dehydrogenase activity
DSM104635_02418	COG0308	aminopeptidase N
DSM104635_02419	COG2202	Pas domain
DSM104635_02419	COG2205	protein histidine kinase activity
DSM104635_02423	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DSM104635_02424	COG0642	Histidine kinase
DSM104635_02424	COG3850	Histidine kinase
DSM104635_02426	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104635_02427	COG3088	subunit of a heme lyase
DSM104635_02428	COG1138	Cytochrome C-type biogenesis protein
DSM104635_02429	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DSM104635_02438	COG4695	Portal protein
DSM104635_02440	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSM104635_02441	COG0488	(ABC) transporter
DSM104635_02444	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DSM104635_02447	COG2205	protein histidine kinase activity
DSM104635_02449	COG2166	iron-sulfur cluster assembly
DSM104635_02455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104635_02468	COG0848	biopolymer transport protein
DSM104635_02469	COG0848	biopolymer transport protein
DSM104635_02471	COG0271	Belongs to the BolA IbaG family
DSM104635_02472	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DSM104635_02473	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104635_02475	COG2326	polyphosphate kinase activity
DSM104635_02483	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM104635_02485	COG3437	response regulator, receiver
DSM104635_02485	COG2205	protein histidine kinase activity
DSM104635_02485	COG3850	Histidine kinase
DSM104635_02485	COG4999	Histidine kinase
DSM104635_02486	COG0346	lactoylglutathione lyase activity
DSM104635_02490	COG0538	isocitrate dehydrogenase activity
DSM104635_02493	COG1024	Enoyl-CoA hydratase
DSM104635_02495	COG0456	acetyltransferase
DSM104635_02496	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSM104635_02497	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSM104635_02500	COG0667	Aldo Keto reductase
DSM104635_02504	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSM104635_02505	COG1684	flagellar biosynthetic protein fliR
DSM104635_02506	COG1987	bacterial-type flagellum assembly
DSM104635_02508	COG1338	Plays a role in the flagellum-specific transport system
DSM104635_02509	COG3190	flagellar
DSM104635_02511	COG1558	bacterial-type flagellum-dependent cell motility
DSM104635_02512	COG1677	Flagellar hook-basal body complex protein FliE
DSM104635_02514	COG5487	UPF0391 membrane protein
DSM104635_02522	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DSM104635_02526	COG2239	Acts as a magnesium transporter
DSM104635_02527	COG1937	Protein conserved in bacteria
DSM104635_02534	COG0321	lipoyl(octanoyl) transferase activity
DSM104635_02538	COG1671	Belongs to the UPF0178 family
DSM104635_02541	COG1234	tRNA 3'-trailer cleavage
DSM104635_02542	COG4770	biotin carboxylase activity
DSM104635_02545	COG1192	Involved in chromosome partitioning
DSM104635_02548	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSM104635_02555	COG4166	transmembrane transport
DSM104635_02556	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104635_02557	COG0601	transmembrane transport
DSM104635_02561	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104635_02564	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104635_02565	COG0259	pyridoxamine-phosphate oxidase activity
DSM104635_02566	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSM104635_02568	COG0154	amidase activity
DSM104635_02569	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DSM104635_02573	COG1024	Enoyl-CoA hydratase
DSM104635_02575	COG2983	Belongs to the UPF0260 family
DSM104635_02576	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSM104635_02579	COG0154	amidase activity
DSM104635_02583	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DSM104635_02584	COG0418	dihydroorotase activity
DSM104635_02589	COG0438	transferase activity, transferring glycosyl groups
DSM104635_02598	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DSM104635_02606	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSM104635_02608	COG3813	Protein conserved in bacteria
DSM104635_02611	COG4221	oxidoreductase activity
DSM104635_02613	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSM104635_02613	COG0574	Belongs to the PEP-utilizing enzyme family
DSM104635_02614	COG0751	glycine-tRNA ligase activity
DSM104635_02616	COG0752	glycyl-tRNA synthetase alpha subunit
DSM104635_02617	COG2267	carboxylic ester hydrolase activity
DSM104635_02621	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSM104635_02629	COG1194	a g-specific adenine glycosylase
DSM104635_02636	COG0356	it plays a direct role in the translocation of protons across the membrane
DSM104635_02637	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM104635_02638	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSM104635_02639	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSM104635_02643	COG1216	Glycosyl transferase, family 2
DSM104635_02643	COG0463	Glycosyl transferase, family 2
DSM104635_02646	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSM104635_02648	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSM104635_02650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSM104635_02653	COG0142	geranyltranstransferase activity
DSM104635_02654	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104635_02655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DSM104635_02659	COG1573	uracil-dna glycosylase
DSM104635_02660	COG0741	lytic transglycosylase activity
DSM104635_02666	COG4786	Flagellar basal body rod
DSM104635_02667	COG4786	Flagellar basal body rod
DSM104635_02669	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DSM104635_02676	COG1706	bacterial-type flagellum-dependent cell motility
DSM104635_02677	COG3951	Flagellar rod assembly protein muramidase FlgJ
DSM104635_02682	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSM104635_02683	COG5442	Flagellar protein FlaF
DSM104635_02686	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104635_02688	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104635_02693	COG0494	nUDIX hydrolase
DSM104635_02694	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_02704	COG3300	MHYT domain
DSM104635_02704	COG5001	Diguanylate cyclase
DSM104635_02706	COG5001	Diguanylate cyclase
DSM104635_02706	COG3300	MHYT domain
DSM104635_02707	COG0784	Response regulator, receiver
DSM104635_02715	COG1127	ABC transporter
DSM104635_02716	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSM104635_02719	COG0772	Belongs to the SEDS family
DSM104635_02720	COG0768	penicillin binding
DSM104635_02729	COG2208	phosphoserine phosphatase activity
DSM104635_02729	COG2770	Histidine kinase
DSM104635_02730	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM104635_02731	COG2205	protein histidine kinase activity
DSM104635_02731	COG0784	Response regulator, receiver
DSM104635_02735	COG3239	Fatty acid desaturase
DSM104635_02737	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DSM104635_02739	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSM104635_02746	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSM104635_02747	COG0560	Phosphoserine phosphatase
DSM104635_02751	COG0330	HflC and HflK could
DSM104635_02752	COG0330	HflC and HflK could
DSM104635_02753	COG0489	protein tyrosine kinase activity
DSM104635_02758	COG0469	pyruvate kinase activity
DSM104635_02760	COG3386	PFAM SMP-30 Gluconolaconase
DSM104635_02762	COG4589	Belongs to the CDS family
DSM104635_02769	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DSM104635_02771	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DSM104635_02777	COG0114	fumarate hydratase activity
DSM104635_02780	COG3152	Membrane
DSM104635_02782	COG0640	Transcriptional regulator
DSM104635_02787	COG2264	protein methyltransferase activity
DSM104635_02789	COG0006	proline dipeptidase activity
DSM104635_02789	COG0006	proline dipeptidase activity
DSM104635_02794	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSM104635_02795	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DSM104635_02802	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104635_02811	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSM104635_02814	COG0626	cystathionine gamma-synthase activity
DSM104635_02816	COG0025	NhaP-type Na H and K H
DSM104635_02817	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSM104635_02823	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM104635_02827	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM104635_02829	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DSM104635_02830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104635_02832	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSM104635_02835	COG0275	rRNA processing
DSM104635_02839	COG3023	N-Acetylmuramoyl-L-alanine amidase
DSM104635_02841	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DSM104635_02842	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DSM104635_02859	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DSM104635_02866	COG4964	Belongs to the GSP D family
DSM104635_02873	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSM104635_02879	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DSM104635_02881	COG0657	acetylesterase activity
DSM104635_02882	COG1605	Chorismate mutase
DSM104635_02882	COG0077	Prephenate dehydratase
DSM104635_02883	COG1595	DNA-templated transcription, initiation
DSM104635_02888	COG2086	electron transfer activity
DSM104635_02889	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSM104635_02890	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104635_02893	COG3128	pkhd-type hydroxylase
DSM104635_02896	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104635_02897	COG0165	Argininosuccinate lyase
DSM104635_02899	COG0019	diaminopimelate decarboxylase activity
DSM104635_02902	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DSM104635_02909	COG0287	Prephenate dehydrogenase
DSM104635_02911	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104635_02916	COG1595	DNA-templated transcription, initiation
DSM104635_02921	COG2226	methyltransferase
DSM104635_02922	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104635_02927	COG1410	methionine synthase
DSM104635_02927	COG0646	methionine synthase
DSM104635_02928	COG0646	methionine synthase
DSM104635_02928	COG1410	methionine synthase
DSM104635_02929	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSM104635_02931	COG2853	Lipoprotein
DSM104635_02933	COG0167	dihydroorotate dehydrogenase activity
DSM104635_02937	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DSM104635_02945	COG1252	NADH dehydrogenase
DSM104635_02946	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DSM104635_02947	COG0083	homoserine kinase activity
DSM104635_02948	COG0460	homoserine dehydrogenase
DSM104635_02948	COG0527	aspartate kinase activity
DSM104635_02949	COG0626	cystathionine gamma-synthase activity
DSM104635_02953	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DSM104635_02955	COG1136	(ABC) transporter
DSM104635_02955	COG0577	efflux transmembrane transporter activity
DSM104635_02956	COG1136	(ABC) transporter
DSM104635_02963	COG0717	Belongs to the dCTP deaminase family
DSM104635_02965	COG2967	ApaG domain
DSM104635_02968	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSM104635_02969	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSM104635_02971	COG2852	Protein conserved in bacteria
DSM104635_02972	COG0842	Transport permease protein
DSM104635_02983	COG1733	regulation of RNA biosynthetic process
DSM104635_02991	COG2814	Major facilitator Superfamily
DSM104635_02994	COG4771	TonB-dependent receptor
DSM104635_02994	COG4771	TonB-dependent receptor
DSM104635_02996	COG2814	Major facilitator Superfamily
DSM104635_02998	COG1024	Enoyl-CoA hydratase
DSM104635_03003	COG1218	3'(2'),5'-bisphosphate nucleotidase
DSM104635_03004	COG0175	sulfate reduction
DSM104635_03006	COG0457	Tetratricopeptide repeat
DSM104635_03008	COG0596	Alpha beta hydrolase
DSM104635_03010	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03012	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03016	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03017	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03019	COG4774	siderophore transport
DSM104635_03020	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DSM104635_03025	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03026	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03027	COG2223	nitrite transmembrane transporter activity
DSM104635_03033	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03035	COG0183	Belongs to the thiolase family
DSM104635_03038	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104635_03039	COG1024	Enoyl-CoA hydratase
DSM104635_03040	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03041	COG1024	Enoyl-CoA hydratase
DSM104635_03043	COG2169	Transcriptional regulator
DSM104635_03048	COG2186	Transcriptional regulator
DSM104635_03053	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104635_03055	COG1024	Enoyl-CoA hydratase
DSM104635_03056	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03057	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03058	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03059	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104635_03059	COG1024	Enoyl-CoA hydratase
DSM104635_03060	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03061	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03062	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03064	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03065	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03066	COG1024	Enoyl-CoA hydratase
DSM104635_03067	COG0183	Belongs to the thiolase family
DSM104635_03069	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03074	COG2188	Transcriptional regulator
DSM104635_03078	COG2124	cytochrome p450
DSM104635_03079	COG0667	Aldo Keto reductase
DSM104635_03082	COG1022	Amp-dependent synthetase and ligase
DSM104635_03082	COG3320	Male sterility
DSM104635_03084	COG1959	2 iron, 2 sulfur cluster binding
DSM104635_03088	COG0730	response to heat
DSM104635_03089	COG1648	precorrin-2 dehydrogenase activity
DSM104635_03090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSM104635_03090	COG1648	precorrin-2 dehydrogenase activity
DSM104635_03093	COG0175	sulfate reduction
DSM104635_03096	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DSM104635_03098	COG3250	beta-galactosidase activity
DSM104635_03102	COG0129	dihydroxy-acid dehydratase activity
DSM104635_03104	COG3734	2-keto-3-deoxy-galactonokinase
DSM104635_03105	COG0800	Aldolase
DSM104635_03106	COG2186	Transcriptional regulator
DSM104635_03110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSM104635_03116	COG1956	GAF domain-containing protein
DSM104635_03118	COG0505	Belongs to the CarA family
DSM104635_03119	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104635_03126	COG0358	DNA primase activity
DSM104635_03127	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DSM104635_03137	COG1309	transcriptional regulator
DSM104635_03147	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSM104635_03148	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSM104635_03150	COG0784	Response regulator, receiver
DSM104635_03151	COG0492	ferredoxin-NADP+ reductase activity
DSM104635_03152	COG1196	nuclear chromosome segregation
DSM104635_03152	COG3264	Mechanosensitive ion channel
DSM104635_03153	COG0583	DNA-binding transcription factor activity
DSM104635_03155	COG2321	neutral zinc metallopeptidase
DSM104635_03164	COG3268	Saccharopine dehydrogenase
DSM104635_03167	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSM104635_03168	COG0085	RNA polymerase activity
DSM104635_03169	COG0222	ribosome binding
DSM104635_03170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSM104635_03178	COG1064	alcohol dehydrogenase
DSM104635_03179	COG0081	regulation of translation
DSM104635_03180	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSM104635_03182	COG3920	Histidine kinase
DSM104635_03183	COG0745	RESPONSE REGULATOR receiver
DSM104635_03184	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DSM104635_03184	COG0392	lysyltransferase activity
DSM104635_03189	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSM104635_03196	COG0640	Transcriptional regulator
DSM104635_03199	COG0625	glutathione transferase activity
DSM104635_03201	COG0625	glutathione transferase activity
DSM104635_03203	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSM104635_03204	COG0049	tRNA binding
DSM104635_03205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DSM104635_03209	COG0556	nucleotide-excision repair
DSM104635_03219	COG4941	Belongs to the sigma-70 factor family
DSM104635_03220	COG3795	YCII-related domain
DSM104635_03222	COG1187	pseudouridine synthase activity
DSM104635_03224	COG0450	alkyl hydroperoxide reductase
DSM104635_03225	COG3453	Protein conserved in bacteria
DSM104635_03225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104635_03228	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DSM104635_03232	COG1278	Cold shock
DSM104635_03235	COG0322	excinuclease ABC activity
DSM104635_03236	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DSM104635_03240	COG0037	tRNA processing
DSM104635_03242	COG2885	chlorophyll binding
DSM104635_03243	COG0823	Involved in the tonB-independent uptake of proteins
DSM104635_03247	COG0824	Thioesterase
DSM104635_03249	COG0640	Transcriptional regulator
DSM104635_03258	COG0667	Aldo Keto reductase
DSM104635_03263	COG2255	four-way junction helicase activity
DSM104635_03265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSM104635_03269	COG0632	four-way junction helicase activity
DSM104635_03273	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DSM104635_03278	COG0653	protein targeting
DSM104635_03279	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104635_03280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DSM104635_03293	COG1278	Cold shock
DSM104635_03298	COG0494	nUDIX hydrolase
DSM104635_03303	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104635_03310	COG0438	transferase activity, transferring glycosyl groups
DSM104635_03312	COG0573	inorganic phosphate transmembrane transporter activity
DSM104635_03313	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSM104635_03315	COG0019	diaminopimelate decarboxylase activity
DSM104635_03321	COG0534	Mate efflux family protein
DSM104635_03322	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DSM104635_03323	COG1899	peptidyl-lysine modification to peptidyl-hypusine
DSM104635_03332	COG2226	methyltransferase
DSM104635_03333	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DSM104635_03337	COG3795	YCII-related domain
DSM104635_03338	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104635_03342	COG0071	Belongs to the small heat shock protein (HSP20) family
DSM104635_03345	COG1278	Cold shock
DSM104635_03347	COG0517	IMP dehydrogenase activity
DSM104635_03347	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSM104635_03353	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104635_03356	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104635_03356	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104635_03357	COG0588	phosphoglycerate mutase activity
DSM104635_03360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DSM104635_03362	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSM104635_03363	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104635_03364	COG0166	Belongs to the GPI family
DSM104635_03369	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM104635_03370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSM104635_03371	COG0673	inositol 2-dehydrogenase activity
DSM104635_03393	COG4122	O-methyltransferase activity
DSM104635_03407	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSM104635_03407	COG0546	phosphoglycolate phosphatase activity
DSM104635_03408	COG0277	FAD linked oxidase domain protein
DSM104635_03414	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104635_03420	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DSM104635_03421	COG1091	dTDP-4-dehydrorhamnose reductase activity
DSM104635_03422	COG1088	dTDP-glucose 4,6-dehydratase activity
DSM104635_03423	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DSM104635_03428	COG2942	2-epimerase
DSM104635_03430	COG1404	Belongs to the peptidase S8 family
DSM104635_03432	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DSM104635_03434	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSM104635_03435	COG0363	glucosamine-6-phosphate deaminase activity
DSM104635_03439	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104635_03452	COG4964	Belongs to the GSP D family
DSM104635_03472	COG2124	cytochrome p450
DSM104635_03479	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104635_03482	COG0436	Aminotransferase
DSM104635_03484	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104635_03486	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSM104635_03488	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DSM104635_03492	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSM104635_03496	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSM104635_03497	COG0784	Response regulator, receiver
DSM104635_03497	COG2205	protein histidine kinase activity
DSM104635_03500	COG2072	flavoprotein involved in K transport
DSM104635_03501	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DSM104635_03502	COG0539	negative regulation of cytoplasmic translation
DSM104635_03505	COG1970	mechanosensitive ion channel activity
DSM104635_03506	COG0135	phosphoribosylanthranilate isomerase activity
DSM104635_03507	COG0133	tryptophan synthase activity
DSM104635_03509	COG0159	tryptophan synthase activity
DSM104635_03510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DSM104635_03511	COG0285	dihydrofolate synthase activity
DSM104635_03514	COG2887	Belongs to the helicase family. UvrD subfamily
DSM104635_03515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DSM104635_03516	COG3178	'Phosphotransferase
DSM104635_03518	COG0633	Ferredoxin
DSM104635_03521	COG2205	protein histidine kinase activity
DSM104635_03522	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DSM104635_03523	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DSM104635_03529	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104635_03531	COG2205	protein histidine kinase activity
DSM104635_03532	COG0745	RESPONSE REGULATOR receiver
DSM104635_03538	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104635_03538	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104635_03542	COG1131	(ABC) transporter
DSM104635_03544	COG0667	Aldo Keto reductase
DSM104635_03546	COG1942	4-Oxalocrotonate Tautomerase
DSM104635_03555	COG0776	regulation of translation
DSM104635_03564	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03564	COG0604	alcohol dehydrogenase
DSM104635_03564	COG3321	synthase
DSM104635_03572	COG0697	spore germination
DSM104635_03574	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSM104635_03585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DSM104635_03588	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM104635_03588	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSM104635_03589	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSM104635_03593	COG0138	bifunctional purine biosynthesis protein purh
DSM104635_03595	COG0386	Belongs to the glutathione peroxidase family
DSM104635_03597	COG2902	Dehydrogenase
DSM104635_03598	COG0628	permease
DSM104635_03599	COG0433	COG0433 Predicted ATPase
DSM104635_03601	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DSM104635_03604	COG2353	YceI-like domain
DSM104635_03612	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DSM104635_03615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DSM104635_03625	COG1131	(ABC) transporter
DSM104635_03626	COG0842	Transport permease protein
DSM104635_03627	COG1086	Polysaccharide biosynthesis protein
DSM104635_03634	COG1960	acyl-CoA dehydrogenase activity
DSM104635_03641	COG0697	spore germination
DSM104635_03642	COG2050	protein possibly involved in aromatic compounds catabolism
DSM104635_03648	COG1217	gtp-binding protein TYPA
DSM104635_03650	COG1396	sequence-specific DNA binding
DSM104635_03656	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DSM104635_03658	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DSM104635_03659	COG1609	Transcriptional regulator
DSM104635_03661	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03663	COG0800	Aldolase
DSM104635_03664	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104635_03666	COG0174	glutamine synthetase
DSM104635_03667	COG1802	Transcriptional regulator
DSM104635_03669	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSM104635_03670	COG3842	ATPase activity
DSM104635_03671	COG1177	transmembrane transport
DSM104635_03672	COG1176	ABC-type spermidine putrescine transport system, permease component I
DSM104635_03675	COG0174	glutamine synthetase
DSM104635_03676	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSM104635_03678	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSM104635_03684	COG0488	(ABC) transporter
DSM104635_03687	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
DSM104635_03688	COG2948	multi-organism process
DSM104635_03691	COG3451	type IV secretory pathway VirB4
DSM104635_03698	COG1872	DUF167
DSM104635_03699	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSM104635_03701	COG0531	amino acid
DSM104635_03702	COG2154	pterin-4-alpha-carbinolamine dehydratase
DSM104635_03705	COG1294	oxidase, subunit
DSM104635_03706	COG1271	oxidase subunit
DSM104635_03707	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03710	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03713	COG0284	orotidine-5'-phosphate decarboxylase activity
DSM104635_03716	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSM104635_03726	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104635_03733	COG5425	PFAM Usg family protein
DSM104635_03735	COG1272	protein, Hemolysin III
DSM104635_03737	COG4249	Peptidase C14 caspase catalytic subunit p20
DSM104635_03740	COG0137	argininosuccinate synthase activity
DSM104635_03745	COG0729	surface antigen
DSM104635_03747	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSM104635_03750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DSM104635_03751	COG0799	negative regulation of ribosome biogenesis
DSM104635_03752	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DSM104635_03754	COG0793	Belongs to the peptidase S41A family
DSM104635_03756	COG0494	nUDIX hydrolase
DSM104635_03759	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSM104635_03762	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DSM104635_03764	COG1764	response to oxidative stress
DSM104635_03765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSM104635_03766	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DSM104635_03767	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM104635_03770	COG0861	Integral membrane protein TerC family
DSM104635_03772	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104635_03776	COG4974	Belongs to the 'phage' integrase family
DSM104635_03785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104635_03791	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104635_03795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DSM104635_03803	COG0045	succinate-CoA ligase (ADP-forming) activity
DSM104635_03804	COG2059	Chromate
DSM104635_03812	COG0039	L-malate dehydrogenase activity
DSM104635_03815	COG4122	O-methyltransferase activity
DSM104635_03816	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DSM104635_03817	COG1396	sequence-specific DNA binding
DSM104635_03818	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DSM104635_03819	COG1253	flavin adenine dinucleotide binding
DSM104635_03821	COG1702	phosphate starvation-inducible protein PhoH
DSM104635_03822	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM104635_03825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DSM104635_03827	COG0180	Tryptophanyl-tRNA synthetase
DSM104635_03829	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DSM104635_03831	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSM104635_03832	COG0280	phosphate acetyltransferase
DSM104635_03832	COG0281	malic enzyme
DSM104635_03833	COG2223	nitrite transmembrane transporter activity
DSM104635_03835	COG0606	chelatase, subunit chli
DSM104635_03845	COG0792	nuclease activity
DSM104635_03846	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSM104635_03848	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSM104635_03849	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DSM104635_03851	COG3655	Transcriptional regulator
DSM104635_03854	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DSM104635_03855	COG1420	regulation of RNA biosynthetic process
DSM104635_03856	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSM104635_03858	COG0667	Aldo Keto reductase
DSM104635_03859	COG0412	Dienelactone hydrolase
DSM104635_03862	COG0443	Heat shock 70 kDa protein
DSM104635_03863	COG0484	heat shock protein binding
DSM104635_03866	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DSM104635_03868	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSM104635_03871	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM104635_03872	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DSM104635_03873	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DSM104635_03874	COG3300	MHYT domain
DSM104635_03874	COG5001	Diguanylate cyclase
DSM104635_03877	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DSM104635_03878	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DSM104635_03879	COG0237	dephospho-CoA kinase activity
DSM104635_03880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSM104635_03881	COG0424	maF-like protein
DSM104635_03882	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DSM104635_03883	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DSM104635_03884	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DSM104635_03885	COG1981	membrane
DSM104635_03886	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSM104635_03890	COG0584	glycerophosphoryl diester phosphodiesterase
DSM104635_03893	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSM104635_03894	COG0445	tRNA wobble uridine modification
DSM104635_03899	COG0436	Aminotransferase
DSM104635_03902	COG1301	dicarboxylic acid transport
DSM104635_03908	COG0495	leucyl-tRNA aminoacylation
DSM104635_03913	COG0745	RESPONSE REGULATOR receiver
DSM104635_03915	COG1024	Enoyl-CoA hydratase
DSM104635_03916	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DSM104635_03925	COG1674	ftsk spoiiie
DSM104635_03926	COG0004	ammonium transporteR
DSM104635_03927	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104635_03928	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSM104635_03934	COG4774	siderophore transport
DSM104635_03936	COG2835	tetraacyldisaccharide 4'-kinase activity
DSM104635_03937	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSM104635_03942	COG0681	Belongs to the peptidase S26 family
DSM104635_03945	COG1946	Acyl-CoA thioesterase
DSM104635_03948	COG2766	serine protein kinase
DSM104635_03949	COG2718	Belongs to the UPF0229 family
DSM104635_03950	COG2719	SpoVR family
DSM104635_03952	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSM104635_03956	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DSM104635_03958	COG0779	Required for maturation of 30S ribosomal subunits
DSM104635_03961	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSM104635_03961	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSM104635_03963	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DSM104635_03964	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSM104635_03965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSM104635_03966	COG1185	polyribonucleotide nucleotidyltransferase activity
DSM104635_03971	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DSM104635_03975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSM104635_03980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DSM104635_03980	COG2885	chlorophyll binding
DSM104635_03983	COG0366	Alpha amylase catalytic
DSM104635_03984	COG3237	CsbD-like
DSM104635_03988	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSM104635_03991	COG0756	dUTP diphosphatase activity
DSM104635_03993	COG0640	Transcriptional regulator
DSM104635_03995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSM104635_03996	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSM104635_03997	COG2226	methyltransferase
DSM104635_04001	COG1024	Enoyl-CoA hydratase
DSM104635_04002	COG0268	Binds directly to 16S ribosomal RNA