locus-tag	class	description
FTW19_00005	COG0358	DNA primase activity
FTW19_00010	COG0438	transferase activity, transferring glycosyl groups
FTW19_00025	COG1278	Cold shock
FTW19_00040	COG1104	cysteine desulfurase activity
FTW19_00060	COG0316	Belongs to the HesB IscA family
FTW19_00085	COG0633	Ferredoxin
FTW19_00095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FTW19_00105	COG3706	GGDEF domain
FTW19_00105	COG0745	RESPONSE REGULATOR receiver
FTW19_00160	COG2326	polyphosphate kinase activity
FTW19_00180	COG1136	(ABC) transporter
FTW19_00180	COG0577	efflux transmembrane transporter activity
FTW19_00230	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FTW19_00285	COG4249	Peptidase C14 caspase catalytic subunit p20
FTW19_00290	COG3706	GGDEF domain
FTW19_00290	COG0745	RESPONSE REGULATOR receiver
FTW19_00345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FTW19_00350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FTW19_00365	COG0667	Aldo Keto reductase
FTW19_00390	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FTW19_00395	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FTW19_00405	COG2234	aminopeptidase activity
FTW19_00410	COG0124	histidyl-tRNA synthetase
FTW19_00420	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_00430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FTW19_00435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FTW19_00440	COG3494	Protein of unknown function (DUF1009)
FTW19_00445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FTW19_00455	COG3584	3D domain protein
FTW19_00455	COG1388	LysM domain
FTW19_00460	COG0481	GTPase activity
FTW19_00475	COG3275	phosphorelay sensor kinase activity
FTW19_00480	COG3279	Response regulator of the LytR AlgR family
FTW19_00490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FTW19_00525	COG3415	Transposase
FTW19_00525	COG2801	Transposase and inactivated derivatives
FTW19_00530	COG0443	Heat shock 70 kDa protein
FTW19_00535	COG2318	DinB family
FTW19_00545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FTW19_00550	COG1063	alcohol dehydrogenase
FTW19_00555	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_00565	COG2271	Major facilitator Superfamily
FTW19_00570	COG2217	Heavy metal translocating P-type atpase
FTW19_00580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FTW19_00590	COG0557	exoribonuclease II activity
FTW19_00595	COG1231	oxidoreductase activity
FTW19_00605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FTW19_00610	COG0254	rRNA binding
FTW19_00640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FTW19_00650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FTW19_00670	COG1620	l-lactate permease
FTW19_00680	COG3537	Alpha-1,2-mannosidase
FTW19_00690	COG0460	homoserine dehydrogenase
FTW19_00695	COG0590	tRNA wobble adenosine to inosine editing
FTW19_00700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FTW19_00710	COG2351	hydroxyisourate hydrolase activity
FTW19_00720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FTW19_00760	COG0477	Major facilitator Superfamily
FTW19_00765	COG1335	isochorismatase
FTW19_00795	COG0513	Belongs to the DEAD box helicase family
FTW19_00800	COG1228	amidohydrolase
FTW19_00805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTW19_00810	COG1187	pseudouridine synthase activity
FTW19_00815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FTW19_00820	COG0626	cystathionine gamma-synthase activity
FTW19_00825	COG0626	cystathionine gamma-synthase activity
FTW19_00830	COG0402	S-adenosylhomocysteine deaminase activity
FTW19_00840	COG0583	DNA-binding transcription factor activity
FTW19_00850	COG0175	sulfate reduction
FTW19_00865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FTW19_00870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FTW19_00895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FTW19_00920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FTW19_00925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FTW19_00935	COG2318	DinB family
FTW19_00955	COG0504	CTP synthase activity
FTW19_00985	COG0788	formyltetrahydrofolate deformylase activity
FTW19_00990	COG3850	Histidine kinase
FTW19_01055	COG3537	Alpha-1,2-mannosidase
FTW19_01065	COG4941	Belongs to the sigma-70 factor family
FTW19_01070	COG3795	YCII-related domain
FTW19_01100	COG2814	Major facilitator Superfamily
FTW19_01120	COG1802	Transcriptional regulator
FTW19_01145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FTW19_01150	COG4191	Histidine kinase
FTW19_01155	COG3850	Histidine kinase
FTW19_01155	COG3437	response regulator, receiver
FTW19_01155	COG4999	Histidine kinase
FTW19_01155	COG2205	protein histidine kinase activity
FTW19_01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FTW19_01180	COG2267	carboxylic ester hydrolase activity
FTW19_01200	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FTW19_01205	COG1914	H( )-stimulated, divalent metal cation uptake system
FTW19_01225	COG0306	phosphate transporter
FTW19_01230	COG3795	YCII-related domain
FTW19_01235	COG4941	Belongs to the sigma-70 factor family
FTW19_01245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FTW19_01270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FTW19_01295	COG1082	Xylose isomerase domain protein TIM barrel
FTW19_01340	COG0312	modulator of DNA gyrase
FTW19_01345	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_01350	COG0312	modulator of DNA gyrase
FTW19_01380	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FTW19_01385	COG3706	GGDEF domain
FTW19_01390	COG2255	four-way junction helicase activity
FTW19_01400	COG2346	COG2346, Truncated hemoglobins
FTW19_01405	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_01435	COG0583	DNA-binding transcription factor activity
FTW19_01445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_01450	COG1538	Outer membrane efflux protein
FTW19_01465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FTW19_01470	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FTW19_01475	COG2080	2 iron, 2 sulfur cluster binding
FTW19_01490	COG1555	photosystem II stabilization
FTW19_01495	COG0135	phosphoribosylanthranilate isomerase activity
FTW19_01500	COG0134	indole-3-glycerol-phosphate synthase activity
FTW19_01535	COG2223	nitrite transmembrane transporter activity
FTW19_01540	COG5265	(ABC) transporter
FTW19_01545	COG3119	arylsulfatase activity
FTW19_01630	COG0058	SHG alpha-glucan phosphorylase activity
FTW19_01650	COG1595	DNA-templated transcription, initiation
FTW19_01670	COG0287	Prephenate dehydrogenase
FTW19_01675	COG2975	iron-sulfur cluster assembly
FTW19_01695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FTW19_01725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FTW19_01730	COG0077	Prephenate dehydratase
FTW19_01730	COG1605	Chorismate mutase
FTW19_01735	COG0159	tryptophan synthase activity
FTW19_01740	COG0133	tryptophan synthase activity
FTW19_01750	COG2814	Major facilitator Superfamily
FTW19_01760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FTW19_01770	COG2353	YceI-like domain
FTW19_01775	COG1741	Belongs to the pirin family
FTW19_01780	COG1846	Transcriptional regulator
FTW19_01785	COG3706	GGDEF domain
FTW19_01785	COG0745	RESPONSE REGULATOR receiver
FTW19_01790	COG3132	Protein of unknown function, DUF480
FTW19_01795	COG0583	DNA-binding transcription factor activity
FTW19_01810	COG0501	Belongs to the peptidase M48B family
FTW19_01825	COG0281	malic enzyme
FTW19_01830	COG2081	HI0933 family
FTW19_01860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FTW19_01860	COG2755	lipolytic protein G-D-S-L family
FTW19_01870	COG1136	(ABC) transporter
FTW19_01870	COG0577	efflux transmembrane transporter activity
FTW19_01880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_01895	COG1845	cytochrome c oxidase, subunit III
FTW19_01900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FTW19_01905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FTW19_01940	COG0437	4 iron, 4 sulfur cluster binding
FTW19_01955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FTW19_01975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FTW19_01980	COG1309	transcriptional regulator
FTW19_01985	COG1017	nitric oxide dioxygenase activity
FTW19_01985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FTW19_01990	COG1959	2 iron, 2 sulfur cluster binding
FTW19_02015	COG2897	thiosulfate sulfurtransferase activity
FTW19_02025	COG0501	Belongs to the peptidase M48B family
FTW19_02055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FTW19_02065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FTW19_02075	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FTW19_02095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FTW19_02100	COG0537	adenosine 5'-monophosphoramidase activity
FTW19_02120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FTW19_02125	COG0583	DNA-binding transcription factor activity
FTW19_02140	COG1136	(ABC) transporter
FTW19_02140	COG0577	efflux transmembrane transporter activity
FTW19_02145	COG2080	2 iron, 2 sulfur cluster binding
FTW19_02150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FTW19_02155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FTW19_02160	COG2203	Gaf domain
FTW19_02160	COG3706	GGDEF domain
FTW19_02160	COG5001	Diguanylate cyclase
FTW19_02160	COG4251	negative regulation of phosphorylation
FTW19_02165	COG2172	sigma factor antagonist activity
FTW19_02170	COG2172	sigma factor antagonist activity
FTW19_02175	COG1366	Belongs to the anti-sigma-factor antagonist family
FTW19_02180	COG1366	Belongs to the anti-sigma-factor antagonist family
FTW19_02195	COG1408	metallophosphoesterase
FTW19_02210	COG0577	efflux transmembrane transporter activity
FTW19_02210	COG1136	(ABC) transporter
FTW19_02230	COG1312	Catalyzes the dehydration of D-mannonate
FTW19_02235	COG0673	inositol 2-dehydrogenase activity
FTW19_02250	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FTW19_02280	COG1725	Transcriptional regulator
FTW19_02300	COG1136	(ABC) transporter
FTW19_02300	COG0577	efflux transmembrane transporter activity
FTW19_02315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FTW19_02335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FTW19_02340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FTW19_02355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FTW19_02360	COG0706	membrane insertase activity
FTW19_02380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FTW19_02415	COG0632	four-way junction helicase activity
FTW19_02430	COG0577	efflux transmembrane transporter activity
FTW19_02440	COG2205	protein histidine kinase activity
FTW19_02445	COG0745	RESPONSE REGULATOR receiver
FTW19_02460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FTW19_02525	COG0776	regulation of translation
FTW19_02550	COG4221	oxidoreductase activity
FTW19_02555	COG2860	membrane
FTW19_02575	COG1192	Involved in chromosome partitioning
FTW19_02580	COG0357	Ribosomal RNA small subunit methyltransferase G
FTW19_02585	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FTW19_02590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FTW19_02595	COG0343	queuine tRNA-ribosyltransferase activity
FTW19_02605	COG1862	Preprotein translocase
FTW19_02610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FTW19_02615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FTW19_02670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FTW19_02680	COG0386	Belongs to the glutathione peroxidase family
FTW19_02685	COG0592	DNA-directed DNA polymerase activity
FTW19_02695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FTW19_02705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FTW19_02730	COG0305	Participates in initiation and elongation during chromosome replication
FTW19_02740	COG0445	tRNA wobble uridine modification
FTW19_02755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FTW19_02760	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FTW19_02780	COG1733	regulation of RNA biosynthetic process
FTW19_02785	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FTW19_02790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FTW19_02815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FTW19_02835	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FTW19_02840	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FTW19_02855	COG0799	negative regulation of ribosome biogenesis
FTW19_02860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FTW19_02875	COG3590	peptidase
FTW19_02900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FTW19_02915	COG3655	Transcriptional regulator
FTW19_02940	COG3275	phosphorelay sensor kinase activity
FTW19_02945	COG3279	Response regulator of the LytR AlgR family
FTW19_02960	COG0515	serine threonine protein kinase
FTW19_02985	COG3415	Transposase
FTW19_02985	COG2801	Transposase and inactivated derivatives
FTW19_02995	COG0745	RESPONSE REGULATOR receiver
FTW19_03115	COG0577	efflux transmembrane transporter activity
FTW19_03115	COG1136	(ABC) transporter
FTW19_03145	COG2197	response regulator
FTW19_03155	COG3781	membrane
FTW19_03170	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
FTW19_03200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FTW19_03215	COG1136	(ABC) transporter
FTW19_03215	COG0577	efflux transmembrane transporter activity
FTW19_03225	COG1268	BioY protein
FTW19_03245	COG2249	NAD(P)H dehydrogenase (quinone) activity
FTW19_03250	COG4303	Ethanolamine ammonia lyase large subunit
FTW19_03255	COG4302	ethanolamine ammonia-lyase activity
FTW19_03260	COG0113	porphobilinogen synthase activity
FTW19_03275	COG1193	negative regulation of DNA recombination
FTW19_03295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FTW19_03300	COG0321	lipoyl(octanoyl) transferase activity
FTW19_03305	COG0508	dehydrogenase complex catalyzes the overall conversion of
FTW19_03325	COG0756	dUTP diphosphatase activity
FTW19_03335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FTW19_03340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FTW19_03355	COG0151	Belongs to the GarS family
FTW19_03360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FTW19_03365	COG0750	zinc metalloprotease
FTW19_03370	COG0742	ribosomal rna small subunit methyltransferase
FTW19_03375	COG0424	maF-like protein
FTW19_03385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FTW19_03395	COG0521	Mo-molybdopterin cofactor biosynthetic process
FTW19_03405	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FTW19_03415	COG0243	molybdopterin cofactor binding
FTW19_03435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FTW19_03440	COG0416	fatty acid biosynthetic process
FTW19_03460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FTW19_03465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FTW19_03480	COG0673	inositol 2-dehydrogenase activity
FTW19_03500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FTW19_03505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FTW19_03555	COG2272	Belongs to the type-B carboxylesterase lipase family
FTW19_03595	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FTW19_03615	COG3706	GGDEF domain
FTW19_03620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FTW19_03650	COG1994	Peptidase M50
FTW19_03655	COG0180	Tryptophanyl-tRNA synthetase
FTW19_03665	COG0488	(ABC) transporter
FTW19_03690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FTW19_03695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FTW19_03700	COG0509	glycine decarboxylation via glycine cleavage system
FTW19_03705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FTW19_03725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FTW19_03735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FTW19_03765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FTW19_03770	COG0784	Response regulator, receiver
FTW19_03770	COG2205	protein histidine kinase activity
FTW19_03770	COG5002	protein histidine kinase activity
FTW19_03775	COG3706	GGDEF domain
FTW19_03795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FTW19_03800	COG0564	pseudouridine synthase activity
FTW19_03810	COG0038	chloride channel
FTW19_03815	COG3383	formate dehydrogenase (NAD+) activity
FTW19_03835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FTW19_03840	COG0215	cysteine-tRNA ligase activity
FTW19_03845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FTW19_03875	COG3511	phospholipase C
FTW19_03900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FTW19_03925	COG0406	alpha-ribazole phosphatase activity
FTW19_03935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FTW19_04050	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_04070	COG3275	phosphorelay sensor kinase activity
FTW19_04075	COG3279	Response regulator of the LytR AlgR family
FTW19_04150	COG3108	Peptidase M15
FTW19_04155	COG2226	methyltransferase
FTW19_04170	COG0792	nuclease activity
FTW19_04175	COG0697	spore germination
FTW19_04180	COG3250	beta-galactosidase activity
FTW19_04255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FTW19_04290	COG0438	transferase activity, transferring glycosyl groups
FTW19_04305	COG2837	iron assimilation
FTW19_04330	COG3145	DNA-N1-methyladenine dioxygenase activity
FTW19_04340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FTW19_04380	COG0464	growth
FTW19_04420	COG0154	amidase activity
FTW19_04425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FTW19_04450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FTW19_04465	COG0322	excinuclease ABC activity
FTW19_04475	COG0081	regulation of translation
FTW19_04480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FTW19_04485	COG0222	ribosome binding
FTW19_04490	COG0085	RNA polymerase activity
FTW19_04495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FTW19_04515	COG0346	lactoylglutathione lyase activity
FTW19_04560	COG2910	NAD(P)H-binding
FTW19_04580	COG1181	Belongs to the D-alanine--D-alanine ligase family
FTW19_04595	COG0017	Asparaginyl-tRNA synthetase
FTW19_04615	COG0583	DNA-binding transcription factor activity
FTW19_04625	COG0596	Alpha beta hydrolase
FTW19_04630	COG0405	Gamma-glutamyltransferase
FTW19_04635	COG2814	Major facilitator Superfamily
FTW19_04660	COG0531	amino acid
FTW19_04685	COG0535	radical SAM domain protein
FTW19_04695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FTW19_04735	COG1309	transcriptional regulator
FTW19_04740	COG2814	Major facilitator Superfamily
FTW19_04745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FTW19_04755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FTW19_04760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FTW19_04775	COG0519	Catalyzes the synthesis of GMP from XMP
FTW19_04780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FTW19_04785	COG2027	D-alanyl-D-alanine carboxypeptidase
FTW19_04795	COG1595	DNA-templated transcription, initiation
FTW19_04800	COG2234	aminopeptidase activity
FTW19_04805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FTW19_04810	COG0546	phosphoglycolate phosphatase activity
FTW19_04810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FTW19_04820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FTW19_04835	COG0352	thiamine-phosphate diphosphorylase activity
FTW19_04845	COG0406	alpha-ribazole phosphatase activity
FTW19_04845	COG0328	RNA-DNA hybrid ribonuclease activity
FTW19_04855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FTW19_04865	COG0754	glutathionylspermidine amidase activity
FTW19_04875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FTW19_04895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FTW19_04915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FTW19_04925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FTW19_04930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FTW19_04935	COG3011	Protein conserved in bacteria
FTW19_04940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FTW19_04955	COG0726	polysaccharide deacetylase
FTW19_04960	COG1428	Deoxynucleoside kinase
FTW19_04970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FTW19_04980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FTW19_04985	COG0237	dephospho-CoA kinase activity
FTW19_04990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FTW19_05000	COG0577	efflux transmembrane transporter activity
FTW19_05010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FTW19_05020	COG1538	Outer membrane efflux protein
FTW19_05030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_05040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FTW19_05060	COG2197	response regulator
FTW19_05065	COG4585	Histidine kinase
FTW19_05070	COG2271	Major facilitator Superfamily
FTW19_05075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FTW19_05095	COG0251	oxidation-reduction process
FTW19_05120	COG0277	FAD linked oxidase domain protein
FTW19_05125	COG2706	6-phosphogluconolactonase activity
FTW19_05135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FTW19_05140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FTW19_05145	COG0437	4 iron, 4 sulfur cluster binding
FTW19_05150	COG0243	molybdopterin cofactor binding
FTW19_05155	COG2223	nitrite transmembrane transporter activity
FTW19_05170	COG4585	Histidine kinase
FTW19_05195	COG1472	Belongs to the glycosyl hydrolase 3 family
FTW19_05205	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_05210	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_05230	COG0366	Alpha amylase catalytic
FTW19_05240	COG2723	6-phospho-beta-galactosidase activity
FTW19_05250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FTW19_05255	COG0673	inositol 2-dehydrogenase activity
FTW19_05260	COG1940	carbohydrate kinase activity
FTW19_05320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FTW19_05345	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FTW19_05360	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FTW19_05365	COG0193	aminoacyl-tRNA hydrolase activity
FTW19_05370	COG0360	Binds together with S18 to 16S ribosomal RNA
FTW19_05375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FTW19_05380	COG0359	binds to the 23S rRNA
FTW19_05415	COG0525	valine-tRNA ligase activity
FTW19_05435	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FTW19_05460	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FTW19_05475	COG1764	response to oxidative stress
FTW19_05500	COG4946	Tricorn protease homolog
FTW19_05500	COG1506	peptidase
FTW19_05500	COG0823	Involved in the tonB-independent uptake of proteins
FTW19_05510	COG0681	Belongs to the peptidase S26 family
FTW19_05515	COG0571	ribonuclease III activity
FTW19_05555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_05565	COG1993	acr, cog1993
FTW19_05570	COG1309	transcriptional regulator
FTW19_05595	COG0183	Belongs to the thiolase family
FTW19_05605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FTW19_05610	COG1960	acyl-CoA dehydrogenase activity
FTW19_05615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FTW19_05625	COG1024	Enoyl-CoA hydratase
FTW19_05630	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FTW19_05635	COG3186	Phenylalanine-4-hydroxylase
FTW19_05640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FTW19_05665	COG4585	Histidine kinase
FTW19_05710	COG0531	amino acid
FTW19_05725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FTW19_05770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FTW19_05795	COG0179	Fumarylacetoacetate (FAA) hydrolase
FTW19_05815	COG3119	arylsulfatase activity
FTW19_05860	COG4191	Histidine kinase
FTW19_05865	COG5001	Diguanylate cyclase
FTW19_05865	COG3300	MHYT domain
FTW19_05875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FTW19_05890	COG3275	phosphorelay sensor kinase activity
FTW19_05905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FTW19_05910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FTW19_05915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FTW19_05925	COG1289	transmembrane transporter activity
FTW19_05930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FTW19_05935	COG1201	RNA secondary structure unwinding
FTW19_05980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FTW19_05985	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FTW19_05995	COG3345	alpha-galactosidase
FTW19_06020	COG1309	transcriptional regulator
FTW19_06025	COG4221	oxidoreductase activity
FTW19_06050	COG1519	Transferase
FTW19_06070	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FTW19_06090	COG1160	GTP binding
FTW19_06100	COG1199	ATP-dependent helicase activity
FTW19_06105	COG2755	lipolytic protein G-D-S-L family
FTW19_06115	COG0720	synthase
FTW19_06120	COG0602	queuosine metabolic process
FTW19_06130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FTW19_06145	COG0315	cyclic pyranopterin monophosphate synthase activity
FTW19_06165	COG4191	Histidine kinase
FTW19_06170	COG2204	response regulator
FTW19_06180	COG1674	ftsk spoiiie
FTW19_06185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FTW19_06190	COG2171	N-acyltransferase activity
FTW19_06195	COG0657	acetylesterase activity
FTW19_06195	COG2755	lipolytic protein G-D-S-L family
FTW19_06205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FTW19_06215	COG2309	aminopeptidase activity
FTW19_06220	COG4206	TonB-dependent receptor
FTW19_06225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FTW19_06230	COG0527	aspartate kinase activity
FTW19_06270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FTW19_06280	COG0860	N-Acetylmuramoyl-L-alanine amidase
FTW19_06300	COG0626	cystathionine gamma-synthase activity
FTW19_06315	COG0745	RESPONSE REGULATOR receiver
FTW19_06345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FTW19_06350	COG2226	methyltransferase
FTW19_06355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FTW19_06360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FTW19_06375	COG0805	protein transport
FTW19_06380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FTW19_06385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FTW19_06400	COG0735	belongs to the Fur family
FTW19_06405	COG0450	alkyl hydroperoxide reductase
FTW19_06410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FTW19_06415	COG2234	aminopeptidase activity
FTW19_06435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FTW19_06440	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FTW19_06450	COG0535	radical SAM domain protein
FTW19_06465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FTW19_06480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FTW19_06485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FTW19_06490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FTW19_06495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FTW19_06500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FTW19_06535	COG3706	GGDEF domain
FTW19_06540	COG3852	Histidine kinase
FTW19_06545	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FTW19_06575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FTW19_06580	COG0248	Ppx GppA phosphatase
FTW19_06590	COG3415	Transposase
FTW19_06590	COG2801	Transposase and inactivated derivatives
FTW19_06645	COG0482	sulfurtransferase activity
FTW19_06665	COG0372	Belongs to the citrate synthase family
FTW19_06670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FTW19_06685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FTW19_06685	COG1796	DNA polymerase
FTW19_06690	COG1278	Cold shock
FTW19_06700	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FTW19_06730	COG1297	OPT oligopeptide transporter protein
FTW19_06740	COG1040	competence protein
FTW19_06770	COG1136	(ABC) transporter
FTW19_06770	COG0577	efflux transmembrane transporter activity
FTW19_06780	COG3622	Belongs to the hyi family
FTW19_06810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FTW19_06815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FTW19_06840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FTW19_06845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FTW19_06850	COG0052	Belongs to the universal ribosomal protein uS2 family
FTW19_06855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FTW19_06860	COG1690	Belongs to the RtcB family
FTW19_06875	COG0444	Belongs to the ABC transporter superfamily
FTW19_06880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FTW19_06895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FTW19_06900	COG0531	amino acid
FTW19_06920	COG1902	pentaerythritol trinitrate reductase activity
FTW19_06925	COG0393	Putative heavy-metal-binding
FTW19_06930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FTW19_06940	COG0045	succinate-CoA ligase (ADP-forming) activity
FTW19_06945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FTW19_06955	COG0154	amidase activity
FTW19_06965	COG1435	thymidine kinase activity
FTW19_06970	COG2032	superoxide dismutase activity
FTW19_06980	COG1595	DNA-templated transcription, initiation
FTW19_07000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FTW19_07005	COG3663	DNA glycosylase
FTW19_07020	COG0386	Belongs to the glutathione peroxidase family
FTW19_07040	COG2183	response to ionizing radiation
FTW19_07045	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_07055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FTW19_07065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FTW19_07070	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FTW19_07075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FTW19_07080	COG0363	glucosamine-6-phosphate deaminase activity
FTW19_07085	COG0837	glucose binding
FTW19_07090	COG2827	Endonuclease containing a URI domain
FTW19_07115	COG2226	methyltransferase
FTW19_07120	COG0640	Transcriptional regulator
FTW19_07125	COG4702	Belongs to the UPF0303 family
FTW19_07135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FTW19_07160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FTW19_07170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FTW19_07175	COG0277	FAD linked oxidase domain protein
FTW19_07180	COG2204	response regulator
FTW19_07185	COG5000	phosphorelay sensor kinase activity
FTW19_07190	COG3585	molybdate ion transport
FTW19_07200	COG0686	Belongs to the AlaDH PNT family
FTW19_07210	COG1792	Involved in formation and maintenance of cell shape
FTW19_07220	COG0768	penicillin binding
FTW19_07225	COG0772	Belongs to the SEDS family
FTW19_07230	COG1530	ribonuclease E activity
FTW19_07230	COG1530	ribonuclease E activity
FTW19_07245	COG0006	proline dipeptidase activity
FTW19_07255	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FTW19_07275	COG1064	alcohol dehydrogenase
FTW19_07280	COG2207	Transcriptional regulator
FTW19_07285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FTW19_07290	COG1254	Belongs to the acylphosphatase family
FTW19_07300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FTW19_07310	COG1335	isochorismatase
FTW19_07330	COG0824	Thioesterase
FTW19_07350	COG2860	membrane
FTW19_07370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FTW19_07375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FTW19_07380	COG0628	permease
FTW19_07385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FTW19_07395	COG1027	Aspartate ammonia-lyase
FTW19_07415	COG0492	ferredoxin-NADP+ reductase activity
FTW19_07420	COG3852	Histidine kinase
FTW19_07435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_07450	COG4221	oxidoreductase activity
FTW19_07455	COG2885	chlorophyll binding
FTW19_07460	COG2197	response regulator
FTW19_07495	COG2855	membrane
FTW19_07500	COG1063	alcohol dehydrogenase
FTW19_07505	COG0156	8-amino-7-oxononanoate synthase activity
FTW19_07510	COG2353	YceI-like domain
FTW19_07515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTW19_07525	COG0492	ferredoxin-NADP+ reductase activity
FTW19_07540	COG1012	belongs to the aldehyde dehydrogenase family
FTW19_07545	COG0726	polysaccharide deacetylase
FTW19_07555	COG2010	Cytochrome c
FTW19_07555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FTW19_07560	COG2080	2 iron, 2 sulfur cluster binding
FTW19_07565	COG0456	acetyltransferase
FTW19_07565	COG1846	Transcriptional regulator
FTW19_07620	COG4796	Type ii and iii secretion system protein
FTW19_07645	COG1501	Belongs to the glycosyl hydrolase 31 family
FTW19_07675	COG2226	methyltransferase
FTW19_07675	COG1073	alpha beta
FTW19_07685	COG0463	Glycosyl transferase, family 2
FTW19_07710	COG4964	Belongs to the GSP D family
FTW19_07775	COG2204	response regulator
FTW19_07855	COG2132	Multicopper oxidase
FTW19_07875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FTW19_07880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FTW19_07885	COG2188	Transcriptional regulator
FTW19_07890	COG1131	(ABC) transporter
FTW19_07915	COG1024	Enoyl-CoA hydratase
FTW19_07920	COG1024	Enoyl-CoA hydratase
FTW19_07925	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FTW19_07935	COG2079	MmgE PrpD family protein
FTW19_07960	COG1597	lipid kinase activity
FTW19_07980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FTW19_08000	COG1012	belongs to the aldehyde dehydrogenase family
FTW19_08010	COG1090	epimerase
FTW19_08020	COG1309	transcriptional regulator
FTW19_08025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FTW19_08035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FTW19_08075	COG2010	Cytochrome c
FTW19_08090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FTW19_08115	COG2271	Major facilitator Superfamily
FTW19_08140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FTW19_08145	COG1696	Membrane protein involved in D-alanine export
FTW19_08160	COG1278	Cold shock
FTW19_08175	COG2205	protein histidine kinase activity
FTW19_08175	COG4191	Histidine kinase
FTW19_08175	COG0745	RESPONSE REGULATOR receiver
FTW19_08230	COG1136	(ABC) transporter
FTW19_08230	COG0577	efflux transmembrane transporter activity
FTW19_08315	COG3209	COG3209 Rhs family protein
FTW19_08325	COG3209	COG3209 Rhs family protein
FTW19_08340	COG0582	viral genome integration into host DNA
FTW19_08355	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FTW19_08365	COG0138	bifunctional purine biosynthesis protein purh
FTW19_08385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FTW19_08435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FTW19_08440	COG0440	acetolactate synthase activity
FTW19_08450	COG0028	Belongs to the TPP enzyme family
FTW19_08455	COG0129	dihydroxy-acid dehydratase activity
FTW19_08460	COG0066	3-isopropylmalate dehydratase activity
FTW19_08465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FTW19_08470	COG0473	3-isopropylmalate dehydrogenase activity
FTW19_08475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FTW19_08480	COG0583	DNA-binding transcription factor activity
FTW19_08530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FTW19_08540	COG5002	protein histidine kinase activity
FTW19_08555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FTW19_08560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FTW19_08565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FTW19_08570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FTW19_08605	COG1278	Cold shock
FTW19_08620	COG0640	Transcriptional regulator
FTW19_08630	COG2204	response regulator
FTW19_08635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FTW19_08645	COG0667	Aldo Keto reductase
FTW19_08665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FTW19_08675	COG1968	undecaprenyl-diphosphatase activity
FTW19_08690	COG1136	(ABC) transporter
FTW19_08690	COG0577	efflux transmembrane transporter activity
FTW19_08695	COG2010	Cytochrome c
FTW19_08695	COG4993	Dehydrogenase
FTW19_08710	COG1785	Belongs to the alkaline phosphatase family
FTW19_08715	COG0477	Major facilitator Superfamily
FTW19_08720	COG1476	TRANSCRIPTIONal
FTW19_08740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FTW19_08745	COG4152	abc transporter atp-binding protein
FTW19_08755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FTW19_08755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FTW19_08760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FTW19_08770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FTW19_08775	COG1570	exodeoxyribonuclease VII activity
FTW19_08830	COG4774	siderophore transport
FTW19_08835	COG3128	pkhd-type hydroxylase
FTW19_08840	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FTW19_08850	COG2001	Belongs to the MraZ family
FTW19_08855	COG0275	rRNA processing
FTW19_08870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FTW19_08875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FTW19_08880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FTW19_08885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FTW19_08890	COG0772	Belongs to the SEDS family
FTW19_08895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FTW19_08980	COG0640	Transcriptional regulator
FTW19_09030	COG0438	transferase activity, transferring glycosyl groups
FTW19_09035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTW19_09075	COG1733	regulation of RNA biosynthetic process
FTW19_09120	COG0673	inositol 2-dehydrogenase activity
FTW19_09125	COG1940	carbohydrate kinase activity
FTW19_09130	COG1070	Carbohydrate kinase
FTW19_09160	COG2801	Transposase and inactivated derivatives
FTW19_09185	COG1136	(ABC) transporter
FTW19_09185	COG0577	efflux transmembrane transporter activity
FTW19_09205	COG0793	Belongs to the peptidase S41A family
FTW19_09210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FTW19_09225	COG3481	metal-dependent phosphohydrolase, HD sub domain
FTW19_09230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FTW19_09235	COG0242	peptide deformylase activity
FTW19_09240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FTW19_09250	COG0456	acetyltransferase
FTW19_09260	COG0688	phosphatidylethanolamine metabolic process
FTW19_09265	COG1183	phosphatidylcholine synthase activity
FTW19_09345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FTW19_09385	COG0306	phosphate transporter
FTW19_09390	COG1392	Phosphate transport regulator
FTW19_09400	COG0473	3-isopropylmalate dehydrogenase activity
FTW19_09405	COG1615	UPF0182 protein
FTW19_09410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FTW19_09450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FTW19_09460	COG0247	lactate metabolic process
FTW19_09460	COG2181	nitrate reductase activity
FTW19_09465	COG1309	transcriptional regulator
FTW19_09470	COG1024	Enoyl-CoA hydratase
FTW19_09470	COG1250	3-hydroxyacyl-CoA dehydrogenase
FTW19_09475	COG0183	Belongs to the thiolase family
FTW19_09480	COG1960	acyl-CoA dehydrogenase activity
FTW19_09485	COG3177	Filamentation induced by cAMP protein fic
FTW19_09505	COG0419	ATPase involved in DNA repair
FTW19_09515	COG0823	Involved in the tonB-independent uptake of proteins
FTW19_09555	COG1172	Belongs to the binding-protein-dependent transport system permease family
FTW19_09560	COG1129	ABC transporter
FTW19_09565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FTW19_09570	COG3958	Transketolase
FTW19_09575	COG3959	Transketolase, thiamine diphosphate binding domain
FTW19_09595	COG0588	phosphoglycerate mutase activity
FTW19_09605	COG1070	Carbohydrate kinase
FTW19_09610	COG2814	Major facilitator Superfamily
FTW19_09615	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FTW19_09620	COG0667	Aldo Keto reductase
FTW19_09625	COG1063	alcohol dehydrogenase
FTW19_09685	COG1501	Belongs to the glycosyl hydrolase 31 family
FTW19_09715	COG0457	Tetratricopeptide repeat
FTW19_09745	COG1802	Transcriptional regulator
FTW19_09750	COG3664	PFAM glycoside hydrolase family 39
FTW19_09755	COG2271	Major facilitator Superfamily
FTW19_09760	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_09790	COG5001	Diguanylate cyclase
FTW19_09790	COG3300	MHYT domain
FTW19_09800	COG4771	TonB-dependent receptor
FTW19_09805	COG4191	Histidine kinase
FTW19_09820	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_09825	COG0738	Major facilitator superfamily
FTW19_09830	COG3618	amidohydrolase
FTW19_09835	COG1869	D-ribose catabolic process
FTW19_09840	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_09845	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_09855	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FTW19_09870	COG3345	alpha-galactosidase
FTW19_09885	COG1609	Transcriptional regulator
FTW19_09895	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_09920	COG3345	alpha-galactosidase
FTW19_09940	COG4251	negative regulation of phosphorylation
FTW19_09975	COG0531	amino acid
FTW19_09980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FTW19_09985	COG1486	melibiose metabolic process
FTW19_10000	COG1609	Transcriptional regulator
FTW19_10005	COG0583	DNA-binding transcription factor activity
FTW19_10010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FTW19_10015	COG2271	Major facilitator Superfamily
FTW19_10020	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_10030	COG2721	sulfolactate sulfo-lyase activity
FTW19_10035	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FTW19_10060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FTW19_10090	COG2201	protein-glutamate methylesterase activity
FTW19_10095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FTW19_10100	COG0643	Histidine kinase
FTW19_10100	COG2198	Histidine kinase
FTW19_10105	COG0835	chemotaxis
FTW19_10135	COG2211	Major facilitator Superfamily
FTW19_10140	COG0673	inositol 2-dehydrogenase activity
FTW19_10150	COG1940	carbohydrate kinase activity
FTW19_10165	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FTW19_10170	COG1085	galactose-1-phosphate uridylyltransferase
FTW19_10175	COG2272	Belongs to the type-B carboxylesterase lipase family
FTW19_10190	COG4677	pectinesterase activity
FTW19_10280	COG0631	protein serine/threonine phosphatase activity
FTW19_10385	COG1215	transferase activity, transferring glycosyl groups
FTW19_10395	COG1216	Glycosyl transferase, family 2
FTW19_10415	COG0438	transferase activity, transferring glycosyl groups
FTW19_10430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTW19_10445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FTW19_10450	COG0367	asparagine synthase
FTW19_10460	COG0438	transferase activity, transferring glycosyl groups
FTW19_10460	COG0297	glycogen (starch) synthase activity
FTW19_10465	COG2244	polysaccharide biosynthetic process
FTW19_10510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FTW19_10520	COG1136	(ABC) transporter
FTW19_10520	COG0577	efflux transmembrane transporter activity
FTW19_10560	COG0583	DNA-binding transcription factor activity
FTW19_10570	COG3279	Response regulator of the LytR AlgR family
FTW19_10575	COG3275	phosphorelay sensor kinase activity
FTW19_10580	COG1228	amidohydrolase
FTW19_10595	COG1228	amidohydrolase
FTW19_10615	COG0641	radical SAM
FTW19_10630	COG1132	(ABC) transporter
FTW19_10645	COG0583	DNA-binding transcription factor activity
FTW19_10650	COG3275	phosphorelay sensor kinase activity
FTW19_10655	COG3279	Response regulator of the LytR AlgR family
FTW19_10670	COG2801	Transposase and inactivated derivatives
FTW19_10690	COG1053	succinate dehydrogenase
FTW19_10700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_10705	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_10710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_10710	COG0649	NAD binding
FTW19_10715	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FTW19_10730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FTW19_10735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_10745	COG0713	ATP synthesis coupled electron transport
FTW19_10750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FTW19_10760	COG1007	ATP synthesis coupled electron transport
FTW19_10765	COG0517	IMP dehydrogenase activity
FTW19_10770	COG0840	transmembrane signaling receptor activity
FTW19_10795	COG2201	protein-glutamate methylesterase activity
FTW19_10800	COG5001	Diguanylate cyclase
FTW19_10800	COG2203	Gaf domain
FTW19_10800	COG4251	negative regulation of phosphorylation
FTW19_10800	COG3706	GGDEF domain
FTW19_10810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FTW19_10830	COG0432	Pfam Uncharacterised protein family UPF0047
FTW19_10835	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_10840	COG2271	Major facilitator Superfamily
FTW19_10885	COG0670	Belongs to the BI1 family
FTW19_10890	COG0673	inositol 2-dehydrogenase activity
FTW19_10915	COG1609	Transcriptional regulator
FTW19_10920	COG0673	inositol 2-dehydrogenase activity
FTW19_10935	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_10975	COG5002	protein histidine kinase activity
FTW19_10985	COG2160	L-arabinose isomerase activity
FTW19_11005	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FTW19_11015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FTW19_11040	COG2205	protein histidine kinase activity
FTW19_11050	COG1132	(ABC) transporter
FTW19_11065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FTW19_11080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FTW19_11090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FTW19_11100	COG0495	leucyl-tRNA aminoacylation
FTW19_11110	COG0519	Catalyzes the synthesis of GMP from XMP
FTW19_11110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FTW19_11130	COG0659	secondary active sulfate transmembrane transporter activity
FTW19_11140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FTW19_11145	COG2204	response regulator
FTW19_11175	COG1132	(ABC) transporter
FTW19_11180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FTW19_11195	COG0745	RESPONSE REGULATOR receiver
FTW19_11200	COG0745	RESPONSE REGULATOR receiver
FTW19_11215	COG0573	inorganic phosphate transmembrane transporter activity
FTW19_11220	COG0581	inorganic phosphate transmembrane transporter activity
FTW19_11225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FTW19_11240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FTW19_11250	COG0741	lytic transglycosylase activity
FTW19_11300	COG1138	Cytochrome C-type biogenesis protein
FTW19_11305	COG2204	response regulator
FTW19_11330	COG0148	phosphopyruvate hydratase activity
FTW19_11335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FTW19_11350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FTW19_11355	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FTW19_11360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FTW19_11395	COG0758	DNA mediated transformation
FTW19_11400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FTW19_11410	COG3852	Histidine kinase
FTW19_11420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FTW19_11440	COG1899	peptidyl-lysine modification to peptidyl-hypusine
FTW19_11460	COG0572	uridine kinase
FTW19_11485	COG5002	protein histidine kinase activity
FTW19_11490	COG0745	RESPONSE REGULATOR receiver
FTW19_11515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FTW19_11525	COG0582	viral genome integration into host DNA
FTW19_11595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FTW19_11595	COG2755	lipolytic protein G-D-S-L family
FTW19_11605	COG0577	efflux transmembrane transporter activity
FTW19_11615	COG1131	(ABC) transporter
FTW19_11630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FTW19_11665	COG0517	IMP dehydrogenase activity
FTW19_11675	COG2205	protein histidine kinase activity
FTW19_11675	COG2202	Pas domain
FTW19_11680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FTW19_11685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_11695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTW19_11710	COG0438	transferase activity, transferring glycosyl groups
FTW19_11720	COG0726	polysaccharide deacetylase
FTW19_11730	COG0438	transferase activity, transferring glycosyl groups
FTW19_11770	COG1596	polysaccharide export
FTW19_11780	COG0438	transferase activity, transferring glycosyl groups
FTW19_11790	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FTW19_11795	COG2076	Multidrug Resistance protein
FTW19_11805	COG0673	inositol 2-dehydrogenase activity
FTW19_11815	COG1215	transferase activity, transferring glycosyl groups
FTW19_11830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_11835	COG2204	response regulator
FTW19_11855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FTW19_11880	COG0583	DNA-binding transcription factor activity
FTW19_11885	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FTW19_11895	COG0745	RESPONSE REGULATOR receiver
FTW19_11895	COG3706	GGDEF domain
FTW19_11905	COG1501	Belongs to the glycosyl hydrolase 31 family
FTW19_11925	COG1940	carbohydrate kinase activity
FTW19_11935	COG0165	Argininosuccinate lyase
FTW19_11940	COG0531	amino acid
FTW19_11975	COG1858	cytochrome C peroxidase
FTW19_12010	COG3850	Histidine kinase
FTW19_12035	COG1879	ABC-type sugar transport system periplasmic component
FTW19_12045	COG1129	ABC transporter
FTW19_12050	COG1609	Transcriptional regulator
FTW19_12075	COG1285	pathogenesis
FTW19_12085	COG0604	alcohol dehydrogenase
FTW19_12090	COG1607	acyl-coa hydrolase
FTW19_12095	COG0489	protein tyrosine kinase activity
FTW19_12100	COG1420	regulation of RNA biosynthetic process
FTW19_12105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FTW19_12110	COG0484	heat shock protein binding
FTW19_12115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FTW19_12120	COG1760	l-serine dehydratase
FTW19_12130	COG0606	chelatase, subunit chli
FTW19_12140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FTW19_12150	COG0515	serine threonine protein kinase
FTW19_12150	COG2815	serine threonine protein kinase
FTW19_12170	COG0552	protein localization to endoplasmic reticulum
FTW19_12175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FTW19_12180	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FTW19_12185	COG1546	Belongs to the CinA family
FTW19_12185	COG1058	Belongs to the CinA family
FTW19_12195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FTW19_12210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FTW19_12220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FTW19_12230	COG0469	pyruvate kinase activity
FTW19_12235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FTW19_12250	COG0776	regulation of translation
FTW19_12255	COG0616	signal peptide processing
FTW19_12270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FTW19_12280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FTW19_12285	COG3842	ATPase activity
FTW19_12290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FTW19_12295	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_12365	COG1136	(ABC) transporter
FTW19_12365	COG0577	efflux transmembrane transporter activity
FTW19_12375	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_12385	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_12390	COG1309	transcriptional regulator
FTW19_12410	COG2208	phosphoserine phosphatase activity
FTW19_12415	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_12440	COG2133	pyrroloquinoline quinone binding
FTW19_12455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FTW19_12470	COG1970	mechanosensitive ion channel activity
FTW19_12485	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FTW19_12495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FTW19_12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FTW19_12525	COG0778	Nitroreductase
FTW19_12540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_12560	COG1362	aminopeptidase activity
FTW19_12570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FTW19_12595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FTW19_12600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FTW19_12605	COG0740	serine-type endopeptidase activity
FTW19_12610	COG0544	peptidyl-prolyl cis-trans isomerase activity
FTW19_12620	COG1573	uracil-dna glycosylase
FTW19_12630	COG0662	Cupin 2, conserved barrel domain protein
FTW19_12635	COG0542	response to heat
FTW19_12655	COG1136	(ABC) transporter
FTW19_12670	COG1640	4-alpha-glucanotransferase
FTW19_12690	COG0577	efflux transmembrane transporter activity
FTW19_12690	COG1136	(ABC) transporter
FTW19_12720	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FTW19_12730	COG0492	ferredoxin-NADP+ reductase activity
FTW19_12750	COG0596	Alpha beta hydrolase
FTW19_12770	COG4191	Histidine kinase
FTW19_12780	COG0667	Aldo Keto reductase
FTW19_12785	COG2801	Transposase and inactivated derivatives
FTW19_12795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FTW19_12800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FTW19_12820	COG0277	FAD linked oxidase domain protein
FTW19_12825	COG0179	Fumarylacetoacetate (FAA) hydrolase
FTW19_12830	COG1024	Enoyl-CoA hydratase
FTW19_12840	COG1501	Belongs to the glycosyl hydrolase 31 family
FTW19_12855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FTW19_12875	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FTW19_12880	COG3537	Alpha-1,2-mannosidase
FTW19_12885	COG1643	Atp-dependent helicase
FTW19_12890	COG2271	Major facilitator Superfamily
FTW19_12895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FTW19_12905	COG2010	Cytochrome c
FTW19_12910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FTW19_12915	COG0704	Plays a role in the regulation of phosphate uptake
FTW19_12920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FTW19_12925	COG1648	precorrin-2 dehydrogenase activity
FTW19_12925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FTW19_12930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FTW19_12935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FTW19_12945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FTW19_12950	COG2971	BadF BadG BcrA BcrD
FTW19_12970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FTW19_12975	COG1904	glucuronate isomerase
FTW19_12985	COG3265	gluconokinase activity
FTW19_12990	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_12995	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_13005	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FTW19_13010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FTW19_13025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTW19_13035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_13045	COG0697	spore germination
FTW19_13050	COG0583	DNA-binding transcription factor activity
FTW19_13065	COG1609	Transcriptional regulator
FTW19_13070	COG2814	Major facilitator Superfamily
FTW19_13075	COG0179	Fumarylacetoacetate (FAA) hydrolase
FTW19_13085	COG0783	Belongs to the Dps family
FTW19_13095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FTW19_13100	COG1278	Cold shock
FTW19_13105	COG1295	ribonuclease BN
FTW19_13115	COG0840	transmembrane signaling receptor activity
FTW19_13130	COG0506	proline dehydrogenase activity
FTW19_13150	COG1595	DNA-templated transcription, initiation
FTW19_13180	COG1053	succinate dehydrogenase
FTW19_13190	COG0114	fumarate hydratase activity
FTW19_13205	COG1566	PFAM secretion protein HlyD family protein
FTW19_13210	COG1289	transmembrane transporter activity
FTW19_13215	COG4566	intracellular signal transduction
FTW19_13220	COG1595	DNA-templated transcription, initiation
FTW19_13225	COG4191	Histidine kinase
FTW19_13245	COG1012	belongs to the aldehyde dehydrogenase family
FTW19_13250	COG4191	Histidine kinase
FTW19_13285	COG4566	intracellular signal transduction
FTW19_13295	COG4191	Histidine kinase
FTW19_13300	COG1250	3-hydroxyacyl-CoA dehydrogenase
FTW19_13310	COG1960	acyl-CoA dehydrogenase activity
FTW19_13315	COG0318	PFAM AMP-dependent synthetase and ligase
FTW19_13325	COG1024	Enoyl-CoA hydratase
FTW19_13330	COG1024	Enoyl-CoA hydratase
FTW19_13335	COG1252	NADH dehydrogenase
FTW19_13350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FTW19_13380	COG3336	cytochrome c oxidase
FTW19_13385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FTW19_13390	COG1127	ABC transporter
FTW19_13450	COG1609	Transcriptional regulator
FTW19_13450	COG2207	Transcriptional regulator
FTW19_13455	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_13470	COG0129	dihydroxy-acid dehydratase activity
FTW19_13475	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_13485	COG1482	cell wall glycoprotein biosynthetic process
FTW19_13490	COG1349	DNA-binding transcription factor activity
FTW19_13520	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_13540	COG4191	Histidine kinase
FTW19_13545	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_13595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FTW19_13620	COG4232	protein-disulfide reductase activity
FTW19_13650	COG1022	Amp-dependent synthetase and ligase
FTW19_13660	COG0025	NhaP-type Na H and K H
FTW19_13665	COG0551	DNA topoisomerase type I activity
FTW19_13665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FTW19_13700	COG0534	Mate efflux family protein
FTW19_13705	COG0577	efflux transmembrane transporter activity
FTW19_13730	COG0823	Involved in the tonB-independent uptake of proteins
FTW19_13755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTW19_13760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTW19_13765	COG1418	mRNA catabolic process
FTW19_13770	COG3119	arylsulfatase activity
FTW19_13785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FTW19_13790	COG0247	lactate metabolic process
FTW19_13790	COG0277	FAD linked oxidase domain protein
FTW19_13830	COG0577	efflux transmembrane transporter activity
FTW19_13835	COG3852	Histidine kinase
FTW19_13850	COG0577	efflux transmembrane transporter activity
FTW19_13850	COG1136	(ABC) transporter
FTW19_13855	COG1136	(ABC) transporter
FTW19_13855	COG0577	efflux transmembrane transporter activity
FTW19_13860	COG1136	(ABC) transporter
FTW19_13860	COG0577	efflux transmembrane transporter activity
FTW19_13870	COG1136	(ABC) transporter
FTW19_13870	COG0577	efflux transmembrane transporter activity
FTW19_13890	COG0583	DNA-binding transcription factor activity
FTW19_13915	COG2318	DinB family
FTW19_13920	COG0641	radical SAM
FTW19_13925	COG2226	methyltransferase
FTW19_13940	COG1032	radical SAM domain protein
FTW19_13945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FTW19_13950	COG1032	radical SAM domain protein
FTW19_13990	COG4964	Belongs to the GSP D family
FTW19_14000	COG1286	toxin biosynthetic process
FTW19_14010	COG1295	ribonuclease BN
FTW19_14015	COG1196	nuclear chromosome segregation
FTW19_14025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FTW19_14030	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FTW19_14045	COG0247	lactate metabolic process
FTW19_14050	COG1139	Iron-sulfur cluster binding protein
FTW19_14055	COG1556	Lactate utilization protein
FTW19_14060	COG3347	Dehydrogenase
FTW19_14060	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_14070	COG0657	acetylesterase activity
FTW19_14070	COG2755	lipolytic protein G-D-S-L family
FTW19_14080	COG0004	ammonium transporteR
FTW19_14085	COG0347	Belongs to the P(II) protein family
FTW19_14100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_14115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FTW19_14120	COG1119	ATPase activity
FTW19_14135	COG0165	Argininosuccinate lyase
FTW19_14140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FTW19_14145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FTW19_14150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FTW19_14155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FTW19_14160	COG1438	arginine binding
FTW19_14165	COG0069	glutamate synthase activity
FTW19_14165	COG0070	glutamate synthase
FTW19_14165	COG0067	glutamate synthase
FTW19_14215	COG1131	(ABC) transporter
FTW19_14235	COG0577	efflux transmembrane transporter activity
FTW19_14235	COG1136	(ABC) transporter
FTW19_14250	COG1022	Amp-dependent synthetase and ligase
FTW19_14260	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FTW19_14270	COG2814	Major facilitator Superfamily
FTW19_14310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FTW19_14320	COG0531	amino acid
FTW19_14330	COG0531	amino acid
FTW19_14340	COG0617	tRNA 3'-terminal CCA addition
FTW19_14345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FTW19_14350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FTW19_14360	COG1573	uracil-dna glycosylase
FTW19_14365	COG0673	inositol 2-dehydrogenase activity
FTW19_14390	COG0673	inositol 2-dehydrogenase activity
FTW19_14420	COG0667	Aldo Keto reductase
FTW19_14435	COG0587	DNA-directed DNA polymerase activity
FTW19_14445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FTW19_14455	COG4941	Belongs to the sigma-70 factor family
FTW19_14460	COG3795	YCII-related domain
FTW19_14480	COG0438	transferase activity, transferring glycosyl groups
FTW19_14505	COG0714	Associated with various cellular activities
FTW19_14555	COG2226	methyltransferase
FTW19_14585	COG0577	efflux transmembrane transporter activity
FTW19_14585	COG1136	(ABC) transporter
FTW19_14590	COG1136	(ABC) transporter
FTW19_14590	COG0577	efflux transmembrane transporter activity
FTW19_14600	COG0577	efflux transmembrane transporter activity
FTW19_14600	COG1136	(ABC) transporter
FTW19_14605	COG1473	amidohydrolase
FTW19_14635	COG1940	carbohydrate kinase activity
FTW19_14650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FTW19_14660	COG0101	tRNA pseudouridine synthase activity
FTW19_14670	COG1331	Highly conserved protein containing a thioredoxin domain
FTW19_14675	COG0668	transmembrane transport
FTW19_14685	COG0022	dehydrogenase e1 component
FTW19_14710	COG0505	Belongs to the CarA family
FTW19_14720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FTW19_14730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FTW19_14740	COG2885	chlorophyll binding
FTW19_14765	COG0497	DNA recombination
FTW19_14775	COG0587	DNA-directed DNA polymerase activity
FTW19_14800	COG0825	malonyl-CoA metabolic process
FTW19_14820	COG0284	orotidine-5'-phosphate decarboxylase activity
FTW19_14850	COG3275	phosphorelay sensor kinase activity
FTW19_14870	COG1174	glycine betaine transport
FTW19_14875	COG1125	glycine betaine transport
FTW19_14875	COG0517	IMP dehydrogenase activity
FTW19_14885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FTW19_14900	COG0126	phosphoglycerate kinase activity
FTW19_14910	COG0149	triose-phosphate isomerase activity
FTW19_14915	COG0028	Belongs to the TPP enzyme family
FTW19_14935	COG0129	dihydroxy-acid dehydratase activity
FTW19_14945	COG0745	RESPONSE REGULATOR receiver
FTW19_14950	COG4191	Histidine kinase
FTW19_15010	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FTW19_15025	COG0840	transmembrane signaling receptor activity
FTW19_15040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FTW19_15045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FTW19_15080	COG3395	kinase activity
FTW19_15085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FTW19_15090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FTW19_15100	COG1454	alcohol dehydrogenase
FTW19_15105	COG1414	Transcriptional regulator
FTW19_15125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FTW19_15160	COG0601	transmembrane transport
FTW19_15165	COG1253	flavin adenine dinucleotide binding
FTW19_15185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FTW19_15195	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FTW19_15200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FTW19_15200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FTW19_15210	COG0514	ATP-dependent DNA helicase (RecQ)
FTW19_15215	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FTW19_15220	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FTW19_15230	COG2204	response regulator
FTW19_15255	COG0584	glycerophosphoryl diester phosphodiesterase
FTW19_15260	COG1063	alcohol dehydrogenase
FTW19_15270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_15285	COG1657	PFAM Prenyltransferase squalene oxidase
FTW19_15290	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FTW19_15295	COG0352	thiamine-phosphate diphosphorylase activity
FTW19_15305	COG0439	Biotin carboxylase
FTW19_15310	COG0511	ligase activity, forming carbon-carbon bonds
FTW19_15315	COG0006	proline dipeptidase activity
FTW19_15320	COG1408	metallophosphoesterase
FTW19_15345	COG2770	Histidine kinase
FTW19_15345	COG2208	phosphoserine phosphatase activity
FTW19_15350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FTW19_15365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FTW19_15385	COG3411	Ferredoxin
FTW19_15395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FTW19_15410	COG0109	protoheme IX farnesyltransferase activity
FTW19_15410	COG1612	heme a metabolic process
FTW19_15460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FTW19_15465	COG1196	nuclear chromosome segregation
FTW19_15465	COG0741	lytic transglycosylase activity
FTW19_15465	COG0739	heme binding
FTW19_15500	COG0217	transcriptional regulatory protein
FTW19_15505	COG2514	catechol 2,3-dioxygenase activity
FTW19_15510	COG0297	glycogen (starch) synthase activity
FTW19_15515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FTW19_15530	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FTW19_15535	COG2022	thiamine diphosphate biosynthetic process
FTW19_15570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_15575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTW19_15580	COG0649	NAD binding
FTW19_15590	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FTW19_15605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FTW19_15615	COG0713	ATP synthesis coupled electron transport
FTW19_15630	COG1007	ATP synthesis coupled electron transport
FTW19_15640	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FTW19_15645	COG0356	it plays a direct role in the translocation of protons across the membrane
FTW19_15660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FTW19_15665	COG1692	metallophosphoesterase
FTW19_15685	COG2076	Multidrug Resistance protein
FTW19_15710	COG0556	nucleotide-excision repair
FTW19_15715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FTW19_15715	COG0512	Glutamine amidotransferase of anthranilate synthase
FTW19_15730	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FTW19_15735	COG1562	ergosterol biosynthetic process
FTW19_15745	COG1063	alcohol dehydrogenase
FTW19_15750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FTW19_15755	COG1127	ABC transporter
FTW19_15760	COG1090	epimerase
FTW19_15765	COG0412	Dienelactone hydrolase
FTW19_15780	COG1185	polyribonucleotide nucleotidyltransferase activity
FTW19_15785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FTW19_15820	COG1706	bacterial-type flagellum-dependent cell motility
FTW19_15825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FTW19_15835	COG4786	Flagellar basal body rod
FTW19_15840	COG4786	Flagellar basal body rod
FTW19_15855	COG1191	sigma factor activity
FTW19_15860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FTW19_15865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FTW19_15890	COG1580	Controls the rotational direction of flagella during chemotaxis
FTW19_15900	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FTW19_15915	COG1157	protein secretion by the type III secretion system
FTW19_15925	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FTW19_15930	COG1766	The M ring may be actively involved in energy transduction
FTW19_15935	COG1677	Flagellar hook-basal body complex protein FliE
FTW19_15940	COG1558	bacterial-type flagellum-dependent cell motility
FTW19_15945	COG1815	bacterial-type flagellum-dependent cell motility
FTW19_15965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FTW19_15970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_15980	COG0546	phosphoglycolate phosphatase activity
FTW19_15990	COG1091	dTDP-4-dehydrorhamnose reductase activity
FTW19_15995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FTW19_16015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FTW19_16030	COG0203	ribosomal protein L17
FTW19_16035	COG0202	RNA polymerase activity
FTW19_16040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FTW19_16045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FTW19_16050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FTW19_16055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FTW19_16060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FTW19_16070	COG0563	adenylate kinase activity
FTW19_16080	COG0200	Binds to the 23S rRNA
FTW19_16085	COG1841	ribosomal large subunit assembly
FTW19_16090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FTW19_16095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FTW19_16100	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FTW19_16105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FTW19_16110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FTW19_16115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FTW19_16125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FTW19_16130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FTW19_16135	COG0255	Belongs to the universal ribosomal protein uL29 family
FTW19_16140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FTW19_16145	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FTW19_16150	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FTW19_16155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FTW19_16160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FTW19_16165	COG0089	rRNA binding
FTW19_16170	COG0088	Forms part of the polypeptide exit tunnel
FTW19_16175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FTW19_16180	COG0051	transcription antitermination factor activity, RNA binding
FTW19_16185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FTW19_16190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FTW19_16195	COG0049	tRNA binding
FTW19_16200	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FTW19_16210	COG0823	Involved in the tonB-independent uptake of proteins
FTW19_16210	COG1506	peptidase
FTW19_16220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FTW19_16225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FTW19_16250	COG0268	Binds directly to 16S ribosomal RNA
FTW19_16265	COG0561	phosphatase activity
FTW19_16270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FTW19_16300	COG1595	DNA-templated transcription, initiation
FTW19_16345	COG0405	Gamma-glutamyltransferase
FTW19_16360	COG1228	amidohydrolase
FTW19_16365	COG0583	DNA-binding transcription factor activity
FTW19_16400	COG0235	Class ii aldolase
FTW19_16425	COG3250	beta-galactosidase activity
FTW19_16445	COG0673	inositol 2-dehydrogenase activity
FTW19_16455	COG3469	chitinase activity
FTW19_16455	COG3325	Belongs to the glycosyl hydrolase 18 family
FTW19_16465	COG0515	serine threonine protein kinase
FTW19_16465	COG2815	serine threonine protein kinase
FTW19_16475	COG3118	belongs to the thioredoxin family
FTW19_16480	COG0083	homoserine kinase activity
FTW19_16485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FTW19_16500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FTW19_16505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FTW19_16515	COG2204	response regulator
FTW19_16540	COG4191	Histidine kinase
FTW19_16550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FTW19_16570	COG1136	(ABC) transporter
FTW19_16575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FTW19_16605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FTW19_16635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FTW19_16645	COG0470	DNA polymerase III
FTW19_16655	COG0009	L-threonylcarbamoyladenylate synthase
FTW19_16670	COG2252	PERMEase
FTW19_16685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FTW19_16685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FTW19_16690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTW19_16695	COG1127	ABC transporter
FTW19_16700	COG0746	molybdenum cofactor guanylyltransferase activity
FTW19_16720	COG1309	transcriptional regulator
FTW19_16730	COG2204	response regulator
FTW19_16735	COG3852	Histidine kinase
FTW19_16745	COG0653	protein targeting
FTW19_16770	COG0494	nUDIX hydrolase
FTW19_16785	COG2239	Acts as a magnesium transporter
FTW19_16790	COG3590	peptidase
FTW19_16805	COG1704	LemA family
FTW19_16825	COG1446	asparaginase
FTW19_16830	COG1132	(ABC) transporter
FTW19_16865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FTW19_16880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FTW19_16885	COG0783	Belongs to the Dps family
FTW19_16900	COG0673	inositol 2-dehydrogenase activity
FTW19_16905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FTW19_16925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_16930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FTW19_16935	COG0489	protein tyrosine kinase activity
FTW19_16960	COG0463	Glycosyl transferase, family 2
FTW19_16970	COG1116	anion transmembrane transporter activity
FTW19_17005	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FTW19_17025	COG1074	ATP-dependent DNA helicase activity
FTW19_17055	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_17065	COG0457	Tetratricopeptide repeat
FTW19_17070	COG2814	Major facilitator Superfamily
FTW19_17070	COG0477	Major facilitator Superfamily
FTW19_17075	COG1609	Transcriptional regulator
FTW19_17095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FTW19_17120	COG2132	Multicopper oxidase
FTW19_17125	COG0475	glutathione-regulated potassium exporter activity
FTW19_17140	COG0463	Glycosyl transferase, family 2
FTW19_17255	COG0842	Transport permease protein
FTW19_17260	COG1131	(ABC) transporter
FTW19_17280	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_17305	COG4993	Dehydrogenase
FTW19_17315	COG3189	MarR family transcriptional regulator
FTW19_17320	COG3852	Histidine kinase
FTW19_17345	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FTW19_17370	COG0006	proline dipeptidase activity
FTW19_17380	COG0596	Alpha beta hydrolase
FTW19_17385	COG1309	transcriptional regulator
FTW19_17395	COG1501	Belongs to the glycosyl hydrolase 31 family
FTW19_17400	COG2249	NAD(P)H dehydrogenase (quinone) activity
FTW19_17415	COG1228	amidohydrolase
FTW19_17435	COG4221	oxidoreductase activity
FTW19_17440	COG2207	Transcriptional regulator
FTW19_17450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FTW19_17450	COG2010	Cytochrome c
FTW19_17455	COG2080	2 iron, 2 sulfur cluster binding
FTW19_17465	COG0667	Aldo Keto reductase
FTW19_17490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FTW19_17495	COG0363	glucosamine-6-phosphate deaminase activity
FTW19_17500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FTW19_17525	COG5001	Diguanylate cyclase
FTW19_17540	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FTW19_17555	COG0438	transferase activity, transferring glycosyl groups
FTW19_17590	COG3944	biosynthesis protein
FTW19_17595	COG3267	Type II secretory pathway component ExeA
FTW19_17595	COG3409	Peptidoglycan-binding domain 1 protein
FTW19_17600	COG0489	protein tyrosine kinase activity
FTW19_17605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTW19_17615	COG0438	transferase activity, transferring glycosyl groups
FTW19_17630	COG0297	glycogen (starch) synthase activity
FTW19_17630	COG0438	transferase activity, transferring glycosyl groups
FTW19_17635	COG2204	response regulator
FTW19_17640	COG2204	response regulator
FTW19_17650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_17655	COG1215	transferase activity, transferring glycosyl groups
FTW19_17815	COG3710	Transcriptional regulator
FTW19_17840	COG4181	ATPase activity
FTW19_17855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FTW19_17860	COG0302	gtp cyclohydrolase
FTW19_17875	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_17885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FTW19_17920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FTW19_17925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FTW19_17945	COG1836	PFAM Integral membrane protein DUF92
FTW19_17965	COG2814	Major facilitator Superfamily
FTW19_17970	COG1309	transcriptional regulator
FTW19_17980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FTW19_17985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FTW19_18020	COG0047	phosphoribosylformylglycinamidine synthase activity
FTW19_18030	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_18040	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FTW19_18045	COG0459	protein refolding
FTW19_18075	COG4206	TonB-dependent receptor
FTW19_18080	COG3142	Participates in the control of copper homeostasis
FTW19_18085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FTW19_18090	COG1349	DNA-binding transcription factor activity
FTW19_18100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FTW19_18105	COG0612	Peptidase, M16
FTW19_18110	COG2165	general secretion pathway protein
FTW19_18160	COG3537	Alpha-1,2-mannosidase
FTW19_18170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FTW19_18175	COG0589	response to stress
FTW19_18195	COG0166	Belongs to the GPI family
FTW19_18200	COG0454	-acetyltransferase
FTW19_18205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FTW19_18210	COG1414	Transcriptional regulator
FTW19_18220	COG1953	Uracil, thiamine, allantoin
FTW19_18240	COG0795	lipopolysaccharide-transporting ATPase activity
FTW19_18250	COG1132	(ABC) transporter
FTW19_18265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FTW19_18275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FTW19_18285	COG0463	Glycosyl transferase, family 2
FTW19_18290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FTW19_18300	COG2009	succinate dehydrogenase
FTW19_18305	COG1053	succinate dehydrogenase
FTW19_18310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FTW19_18360	COG0039	L-malate dehydrogenase activity
FTW19_18365	COG0579	oxidoreductase
FTW19_18370	COG0538	isocitrate dehydrogenase activity
FTW19_18375	COG0174	glutamine synthetase
FTW19_18405	COG0590	tRNA wobble adenosine to inosine editing
FTW19_18410	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_18425	COG1832	CoA-binding protein
FTW19_18440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FTW19_18455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FTW19_18475	COG4948	Mandelate Racemase Muconate Lactonizing
FTW19_18485	COG3956	TIGRFAM MazG family protein
FTW19_18500	COG2885	chlorophyll binding
FTW19_18505	COG0322	excinuclease ABC activity
FTW19_18510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FTW19_18520	COG2321	neutral zinc metallopeptidase
FTW19_18530	COG1280	lysine exporter protein (LysE YggA)
FTW19_18535	COG1280	lysine exporter protein (LysE YggA)
FTW19_18585	COG1349	DNA-binding transcription factor activity
FTW19_18595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FTW19_18605	COG2814	Major facilitator Superfamily
FTW19_18615	COG0584	glycerophosphoryl diester phosphodiesterase
FTW19_18630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FTW19_18645	COG0531	amino acid
FTW19_18650	COG3119	arylsulfatase activity
FTW19_18660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FTW19_18665	COG3622	Belongs to the hyi family
FTW19_18690	COG3706	GGDEF domain
FTW19_18715	COG2318	DinB family
FTW19_18730	COG3579	cysteine-type endopeptidase activity
FTW19_18740	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FTW19_18755	COG3920	Histidine kinase
FTW19_18800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FTW19_18805	COG1619	proteins homologs of microcin C7 resistance protein MccF
FTW19_18810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FTW19_18825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FTW19_18835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FTW19_18845	COG0321	lipoyl(octanoyl) transferase activity
FTW19_18845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FTW19_18865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FTW19_18870	COG3409	Peptidoglycan-binding domain 1 protein
FTW19_18870	COG0793	Belongs to the peptidase S41A family
FTW19_18880	COG3254	rhamnose metabolic process
FTW19_18930	COG1850	ribulose-bisphosphate carboxylase activity
FTW19_18975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FTW19_18980	COG0233	cytoplasmic translational termination
FTW19_18990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FTW19_19005	COG1194	a g-specific adenine glycosylase
FTW19_19020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FTW19_19030	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FTW19_19030	COG0662	Cupin 2, conserved barrel domain protein
FTW19_19040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FTW19_19050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FTW19_19055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FTW19_19065	COG1587	Uroporphyrinogen-III synthase
FTW19_19070	COG0181	hydroxymethylbilane synthase activity
FTW19_19075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FTW19_19085	COG0534	Mate efflux family protein
FTW19_19090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FTW19_19100	COG4166	transmembrane transport
FTW19_19120	COG3664	PFAM glycoside hydrolase family 39
FTW19_19130	COG0681	Belongs to the peptidase S26 family
FTW19_19145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FTW19_19155	COG2165	general secretion pathway protein
FTW19_19170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FTW19_19175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FTW19_19180	COG2204	response regulator
FTW19_19185	COG0018	arginyl-trna synthetase
FTW19_19210	COG0457	Tetratricopeptide repeat
FTW19_19215	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FTW19_19240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_19245	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FTW19_19245	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FTW19_19250	COG0859	PFAM glycosyl transferase family 9
FTW19_19265	COG2201	protein-glutamate methylesterase activity
FTW19_19285	COG0673	inositol 2-dehydrogenase activity
FTW19_19310	COG1837	Belongs to the UPF0109 family
FTW19_19315	COG0228	four-way junction DNA binding
FTW19_19330	COG4191	Histidine kinase
FTW19_19350	COG2373	Large extracellular alpha-helical protein
FTW19_19355	COG3234	Protein of unknown function (DUF1175)
FTW19_19370	COG3459	Glycosyltransferase 36 associated
FTW19_19390	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FTW19_19395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FTW19_19405	COG0667	Aldo Keto reductase
FTW19_19410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FTW19_19410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FTW19_19415	COG0802	atpase or kinase
FTW19_19435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FTW19_19445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FTW19_19450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FTW19_19460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FTW19_19475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FTW19_19480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FTW19_19515	COG0475	glutathione-regulated potassium exporter activity
FTW19_19525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FTW19_19535	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FTW19_19540	COG0195	Participates in both transcription termination and antitermination
FTW19_19545	COG0779	Required for maturation of 30S ribosomal subunits
FTW19_19555	COG0751	glycine-tRNA ligase activity
FTW19_19560	COG0752	glycyl-tRNA synthetase alpha subunit
FTW19_19580	COG1381	Involved in DNA repair and RecF pathway recombination
FTW19_19590	COG0483	inositol monophosphate 1-phosphatase activity
FTW19_19605	COG0314	molybdopterin synthase activity
FTW19_19620	COG2197	response regulator
FTW19_19625	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FTW19_19635	COG1605	Chorismate mutase
FTW19_19635	COG0077	Prephenate dehydratase
FTW19_19650	COG3237	CsbD-like
FTW19_19670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FTW19_19680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FTW19_19685	COG1595	DNA-templated transcription, initiation
FTW19_19705	COG0109	protoheme IX farnesyltransferase activity
FTW19_19720	COG0629	single-stranded DNA binding
FTW19_19740	COG1280	lysine exporter protein (LysE YggA)
FTW19_19760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FTW19_19765	COG0277	FAD linked oxidase domain protein
FTW19_19770	COG0277	FAD linked oxidase domain protein
FTW19_19775	COG0247	lactate metabolic process
FTW19_19780	COG5001	Diguanylate cyclase
FTW19_19780	COG2203	Gaf domain
FTW19_19780	COG4251	negative regulation of phosphorylation
FTW19_19780	COG3706	GGDEF domain
FTW19_19785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FTW19_19805	COG1573	uracil-dna glycosylase
FTW19_19815	COG0194	GDP metabolic process
FTW19_19820	COG1561	YicC-like family, N-terminal region
FTW19_19825	COG1132	(ABC) transporter
FTW19_19830	COG1660	Displays ATPase and GTPase activities
FTW19_19840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FTW19_19860	COG3706	GGDEF domain
FTW19_19865	COG0517	IMP dehydrogenase activity
FTW19_19865	COG0516	GMP reductase activity
FTW19_19885	COG1921	L-seryl-tRNASec selenium transferase activity
FTW19_19925	COG0477	Major facilitator Superfamily
FTW19_19955	COG2146	nitrite reductase [NAD(P)H] activity
FTW19_19990	COG2197	response regulator
FTW19_20000	COG1595	DNA-templated transcription, initiation
FTW19_20025	COG2197	response regulator
FTW19_20030	COG4585	Histidine kinase
FTW19_20040	COG1131	(ABC) transporter
FTW19_20065	COG0529	Catalyzes the synthesis of activated sulfate
FTW19_20075	COG3685	Protein conserved in bacteria
FTW19_20095	COG2188	Transcriptional regulator
FTW19_20110	COG1691	(AIR) carboxylase
FTW19_20125	COG2224	Isocitrate lyase
FTW19_20130	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FTW19_20145	COG3243	poly(R)-hydroxyalkanoic acid synthase
FTW19_20155	COG0183	Belongs to the thiolase family
FTW19_20160	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_20175	COG1228	amidohydrolase
FTW19_20180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FTW19_20185	COG2986	histidine ammonia-lyase
FTW19_20200	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_20210	COG3275	phosphorelay sensor kinase activity
FTW19_20215	COG3279	Response regulator of the LytR AlgR family
FTW19_20270	COG4942	peptidase
FTW19_20285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FTW19_20315	COG0745	RESPONSE REGULATOR receiver
FTW19_20340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FTW19_20360	COG0512	Glutamine amidotransferase of anthranilate synthase
FTW19_20380	COG0667	Aldo Keto reductase
FTW19_20420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FTW19_20430	COG0335	large ribosomal subunit rRNA binding
FTW19_20435	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_20440	COG0789	Transcriptional regulator
FTW19_20460	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FTW19_20465	COG0631	protein serine/threonine phosphatase activity
FTW19_20475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FTW19_20485	COG0705	Rhomboid family
FTW19_20485	COG0457	Tetratricopeptide repeat
FTW19_20505	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FTW19_20550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FTW19_20555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FTW19_20575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FTW19_20580	COG0300	oxidoreductase activity
FTW19_20585	COG0300	oxidoreductase activity
FTW19_20590	COG1309	transcriptional regulator
FTW19_20620	COG0693	protein deglycase activity
FTW19_20625	COG1252	NADH dehydrogenase
FTW19_20660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FTW19_20665	COG1872	DUF167
FTW19_20670	COG3108	Peptidase M15
FTW19_20680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FTW19_20695	COG0251	oxidation-reduction process
FTW19_20710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FTW19_20715	COG1201	RNA secondary structure unwinding
FTW19_20720	COG0295	cytidine deaminase activity
FTW19_20725	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FTW19_20730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FTW19_20750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FTW19_20765	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_20770	COG4783	chaperone-mediated protein folding
FTW19_20780	COG1940	carbohydrate kinase activity
FTW19_20785	COG0586	Pfam SNARE associated Golgi protein
FTW19_20800	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FTW19_20810	COG0673	inositol 2-dehydrogenase activity
FTW19_20815	COG0450	alkyl hydroperoxide reductase
FTW19_20845	COG4221	oxidoreductase activity
FTW19_20865	COG0384	phenazine biosynthesis protein PhzF
FTW19_20890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FTW19_20900	COG2207	Transcriptional regulator
FTW19_20900	COG1917	Cupin 2, conserved barrel domain protein
FTW19_20910	COG1733	regulation of RNA biosynthetic process
FTW19_20970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FTW19_20985	COG1609	Transcriptional regulator
FTW19_21090	COG0589	response to stress
FTW19_21095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FTW19_21105	COG2205	protein histidine kinase activity
FTW19_21105	COG2202	Pas domain
FTW19_21110	COG0784	Response regulator, receiver
FTW19_21115	COG2204	response regulator
FTW19_21130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FTW19_21160	COG1228	amidohydrolase
FTW19_21170	COG4585	Histidine kinase
FTW19_21200	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FTW19_21215	COG1414	Transcriptional regulator
FTW19_21225	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_21240	COG0577	efflux transmembrane transporter activity
FTW19_21240	COG1136	(ABC) transporter
FTW19_21250	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_21300	COG2271	Major facilitator Superfamily
FTW19_21305	COG3250	beta-galactosidase activity
FTW19_21375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_21400	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_21405	COG1063	alcohol dehydrogenase
FTW19_21410	COG2271	Major facilitator Superfamily
FTW19_21415	COG2186	Transcriptional regulator
FTW19_21420	COG2197	response regulator
FTW19_21505	COG1363	Peptidase, m42
FTW19_21530	COG0642	Histidine kinase
FTW19_21535	COG0745	RESPONSE REGULATOR receiver
FTW19_21555	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_21615	COG1131	(ABC) transporter
FTW19_21625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FTW19_21635	COG0438	transferase activity, transferring glycosyl groups
FTW19_21670	COG4977	sequence-specific DNA binding
FTW19_21675	COG0840	transmembrane signaling receptor activity
FTW19_21695	COG1538	Outer membrane efflux protein
FTW19_21710	COG0640	Transcriptional regulator
FTW19_21750	COG3220	belongs to the UPF0276 family
FTW19_21785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FTW19_21790	COG4191	Histidine kinase
FTW19_21815	COG3706	GGDEF domain
FTW19_21815	COG0745	RESPONSE REGULATOR receiver
FTW19_21820	COG1595	DNA-templated transcription, initiation
FTW19_21835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FTW19_21920	COG2801	Transposase and inactivated derivatives
FTW19_21920	COG3415	Transposase
FTW19_21930	COG4191	Histidine kinase
FTW19_21935	COG4566	intracellular signal transduction
FTW19_21965	COG0667	Aldo Keto reductase
FTW19_21995	COG2094	Belongs to the DNA glycosylase MPG family
FTW19_22000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FTW19_22015	COG3706	GGDEF domain
FTW19_22015	COG0745	RESPONSE REGULATOR receiver
FTW19_22020	COG2223	nitrite transmembrane transporter activity
FTW19_22030	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FTW19_22035	COG0438	transferase activity, transferring glycosyl groups
FTW19_22070	COG2205	protein histidine kinase activity
FTW19_22070	COG2198	Histidine kinase
FTW19_22070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FTW19_22070	COG0784	Response regulator, receiver
FTW19_22090	COG0330	HflC and HflK could
FTW19_22105	COG2070	2-Nitropropane dioxygenase
FTW19_22110	COG0251	oxidation-reduction process
FTW19_22120	COG0583	DNA-binding transcription factor activity
FTW19_22150	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FTW19_22155	COG1309	transcriptional regulator
FTW19_22170	COG0577	efflux transmembrane transporter activity
FTW19_22170	COG1136	(ABC) transporter
FTW19_22190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FTW19_22230	COG0706	membrane insertase activity
FTW19_22245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FTW19_22250	COG2258	MOSC domain
FTW19_22255	COG0577	efflux transmembrane transporter activity
FTW19_22255	COG1136	(ABC) transporter
FTW19_22285	COG4774	siderophore transport
FTW19_22310	COG2080	2 iron, 2 sulfur cluster binding
FTW19_22365	COG2258	MOSC domain
FTW19_22375	COG0673	inositol 2-dehydrogenase activity
FTW19_22395	COG0110	maltose O-acetyltransferase activity
FTW19_22415	COG0463	Glycosyl transferase, family 2
FTW19_22460	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FTW19_22490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FTW19_22500	COG0577	efflux transmembrane transporter activity
FTW19_22530	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22535	COG1136	(ABC) transporter
FTW19_22535	COG0577	efflux transmembrane transporter activity
FTW19_22570	COG1335	isochorismatase
FTW19_22575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FTW19_22595	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22600	COG0681	Belongs to the peptidase S26 family
FTW19_22625	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FTW19_22630	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22640	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22645	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22650	COG1902	pentaerythritol trinitrate reductase activity
FTW19_22655	COG0583	DNA-binding transcription factor activity
FTW19_22670	COG2207	Transcriptional regulator
FTW19_22695	COG0667	Aldo Keto reductase
FTW19_22715	COG0154	amidase activity
FTW19_22730	COG0577	efflux transmembrane transporter activity
FTW19_22735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FTW19_22765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FTW19_22770	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_22815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FTW19_22820	COG1064	alcohol dehydrogenase
FTW19_22855	COG0745	RESPONSE REGULATOR receiver
FTW19_22900	COG2801	Transposase and inactivated derivatives
FTW19_22900	COG3415	Transposase
FTW19_22930	COG1309	transcriptional regulator
FTW19_22940	COG1136	(ABC) transporter
FTW19_22960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FTW19_22965	COG0583	DNA-binding transcription factor activity
FTW19_22975	COG4941	Belongs to the sigma-70 factor family
FTW19_23010	COG0583	DNA-binding transcription factor activity
FTW19_23075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FTW19_23100	COG2801	Transposase and inactivated derivatives
FTW19_23100	COG3415	Transposase
FTW19_23115	COG2801	Transposase and inactivated derivatives
FTW19_23115	COG3415	Transposase
FTW19_23155	COG3415	Transposase
FTW19_23155	COG2801	Transposase and inactivated derivatives
FTW19_23180	COG0583	DNA-binding transcription factor activity
FTW19_23265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FTW19_23290	COG3279	Response regulator of the LytR AlgR family
FTW19_23295	COG2801	Transposase and inactivated derivatives
FTW19_23295	COG3415	Transposase
FTW19_23315	COG3415	Transposase
FTW19_23315	COG2801	Transposase and inactivated derivatives
FTW19_23320	COG0745	RESPONSE REGULATOR receiver
FTW19_23320	COG3706	GGDEF domain
FTW19_23325	COG3415	Transposase
FTW19_23325	COG2801	Transposase and inactivated derivatives
FTW19_23330	COG2080	2 iron, 2 sulfur cluster binding
FTW19_23350	COG3415	Transposase
FTW19_23350	COG2801	Transposase and inactivated derivatives
FTW19_23365	COG3415	Transposase
FTW19_23365	COG2801	Transposase and inactivated derivatives
FTW19_23395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_23405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FTW19_23460	COG3795	YCII-related domain
FTW19_23495	COG0137	argininosuccinate synthase activity
FTW19_23505	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FTW19_23510	COG0577	efflux transmembrane transporter activity
FTW19_23515	COG0577	efflux transmembrane transporter activity
FTW19_23515	COG1136	(ABC) transporter
FTW19_23535	COG0326	Molecular chaperone. Has ATPase activity
FTW19_23600	COG3345	alpha-galactosidase
FTW19_23615	COG0583	DNA-binding transcription factor activity
FTW19_23620	COG1335	isochorismatase
FTW19_23625	COG1741	Belongs to the pirin family
FTW19_23655	COG0539	negative regulation of cytoplasmic translation
FTW19_23665	COG1621	beta-fructofuranosidase activity
FTW19_23680	COG0577	efflux transmembrane transporter activity
FTW19_23680	COG1136	(ABC) transporter
FTW19_23690	COG0577	efflux transmembrane transporter activity
FTW19_23690	COG1136	(ABC) transporter
FTW19_23695	COG1695	Transcriptional regulator
FTW19_23720	COG0492	ferredoxin-NADP+ reductase activity
FTW19_23725	COG3710	Transcriptional regulator
FTW19_23730	COG0450	alkyl hydroperoxide reductase
FTW19_23735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FTW19_23735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FTW19_23760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTW19_23765	COG1538	Outer membrane efflux protein
FTW19_23775	COG2208	phosphoserine phosphatase activity
FTW19_23775	COG2770	Histidine kinase
FTW19_23780	COG4106	trans-aconitate 2-methyltransferase activity
FTW19_23810	COG0728	peptidoglycan biosynthetic process
FTW19_23820	COG2272	Belongs to the type-B carboxylesterase lipase family
FTW19_23825	COG3537	Alpha-1,2-mannosidase
FTW19_23850	COG1028	Short-chain dehydrogenase reductase Sdr
FTW19_23860	COG2205	protein histidine kinase activity
FTW19_23865	COG0745	RESPONSE REGULATOR receiver
FTW19_23905	COG0745	RESPONSE REGULATOR receiver
FTW19_23910	COG5002	protein histidine kinase activity
FTW19_24000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FTW19_24000	COG2755	lipolytic protein G-D-S-L family
FTW19_24020	COG1566	PFAM secretion protein HlyD family protein
FTW19_24050	COG1012	belongs to the aldehyde dehydrogenase family
FTW19_24060	COG1482	cell wall glycoprotein biosynthetic process
FTW19_24080	COG0105	UTP biosynthetic process
FTW19_24090	COG3781	membrane
FTW19_24095	COG1136	(ABC) transporter
FTW19_24105	COG0736	holo-[acyl-carrier-protein] synthase activity
FTW19_24125	COG3590	peptidase
FTW19_24150	COG0528	UMP kinase activity
FTW19_24155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_24190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FTW19_24205	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FTW19_24225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FTW19_24230	COG2271	Major facilitator Superfamily
FTW19_24235	COG2186	Transcriptional regulator
FTW19_24245	COG0084	hydrolase, TatD family'
FTW19_24250	COG1666	GTP binding
FTW19_24260	COG0142	geranyltranstransferase activity
FTW19_24265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FTW19_24280	COG0717	Belongs to the dCTP deaminase family
FTW19_24295	COG5002	protein histidine kinase activity
FTW19_24300	COG1560	Kdo2-lipid A biosynthetic process
FTW19_24305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FTW19_24320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FTW19_24320	COG0646	methionine synthase
FTW19_24325	COG1722	exodeoxyribonuclease VII activity
FTW19_24330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FTW19_24355	COG5001	Diguanylate cyclase
FTW19_24355	COG4251	negative regulation of phosphorylation
FTW19_24355	COG2203	Gaf domain
FTW19_24355	COG3706	GGDEF domain
FTW19_24375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FTW19_24380	COG0037	tRNA processing
FTW19_24380	COG0590	tRNA wobble adenosine to inosine editing
FTW19_24390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FTW19_24395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FTW19_24410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FTW19_24420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FTW19_24435	COG1366	Belongs to the anti-sigma-factor antagonist family
FTW19_24440	COG0442	prolyl-tRNA aminoacylation
FTW19_24445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FTW19_24450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FTW19_24450	COG2755	lipolytic protein G-D-S-L family
FTW19_24460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FTW19_24470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FTW19_24485	COG4677	pectinesterase activity
FTW19_24505	COG4952	isomerase
FTW19_24530	COG2801	Transposase and inactivated derivatives
FTW19_24530	COG3415	Transposase
FTW19_24550	COG0336	Belongs to the RNA methyltransferase TrmD family
FTW19_24570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FTW19_24600	COG0484	heat shock protein binding
FTW19_24610	COG0443	Heat shock 70 kDa protein
FTW19_24625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FTW19_24630	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FTW19_24660	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FTW19_24680	COG0577	efflux transmembrane transporter activity
FTW19_24710	COG2814	Major facilitator Superfamily
FTW19_24715	COG3664	PFAM glycoside hydrolase family 39
FTW19_24720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FTW19_24725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FTW19_24740	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FTW19_24760	COG2208	phosphoserine phosphatase activity
FTW19_24785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FTW19_24790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FTW19_24795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FTW19_24800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FTW19_24805	COG0131	Imidazoleglycerol-phosphate dehydratase
FTW19_24815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FTW19_24820	COG0107	imidazoleglycerol-phosphate synthase activity
FTW19_24830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FTW19_24855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FTW19_24860	COG0575	Belongs to the CDS family
FTW19_24865	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FTW19_24870	COG0750	zinc metalloprotease
FTW19_24930	COG2814	Major facilitator Superfamily
FTW19_24970	COG2247	cell wall binding repeat
FTW19_24970	COG0860	N-Acetylmuramoyl-L-alanine amidase
FTW19_24975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FTW19_24980	COG0745	RESPONSE REGULATOR receiver
FTW19_24980	COG3706	GGDEF domain
FTW19_25000	COG2137	regulation of response to DNA damage stimulus
FTW19_25005	COG0681	Belongs to the peptidase S26 family
FTW19_25020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FTW19_25040	COG3279	Response regulator of the LytR AlgR family
FTW19_25060	COG0730	response to heat
FTW19_25065	COG0187	DNA topoisomerase II activity
FTW19_25070	COG2153	protein acetylation
FTW19_25075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FTW19_25080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FTW19_25085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FTW19_25100	COG0658	competence protein
FTW19_25100	COG2333	competence protein COMEC
FTW19_25105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FTW19_25115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FTW19_25140	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FTW19_25145	COG0488	(ABC) transporter
FTW19_25190	COG0438	transferase activity, transferring glycosyl groups
FTW19_25210	COG2308	Evidence 4 Homologs of previously reported genes of
FTW19_25220	COG1305	Transglutaminase-like
FTW19_25235	COG5001	Diguanylate cyclase
FTW19_25255	COG1657	PFAM Prenyltransferase squalene oxidase
FTW19_25270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FTW19_25280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FTW19_25295	COG2268	Band 7 protein
FTW19_25300	COG1842	Phage shock protein A
FTW19_25320	COG2208	phosphoserine phosphatase activity
FTW19_25325	COG1982	Orn Lys Arg decarboxylase major
FTW19_25330	COG0179	Fumarylacetoacetate (FAA) hydrolase
FTW19_25350	COG2814	Major facilitator Superfamily
FTW19_25365	COG0667	Aldo Keto reductase
FTW19_25380	COG1522	sequence-specific DNA binding
FTW19_25390	COG2205	protein histidine kinase activity
FTW19_25405	COG1793	dna ligase
FTW19_25410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FTW19_25415	COG2890	protein-(glutamine-N5) methyltransferase activity
FTW19_25420	COG0745	RESPONSE REGULATOR receiver
FTW19_25420	COG3706	GGDEF domain
FTW19_25425	COG0492	ferredoxin-NADP+ reductase activity
FTW19_25430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTW19_25440	COG0542	response to heat
FTW19_25455	COG4251	negative regulation of phosphorylation
FTW19_25460	COG0784	Response regulator, receiver
FTW19_25485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FTW19_25490	COG0504	CTP synthase activity
FTW19_25500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FTW19_25515	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FTW19_25520	COG0540	Belongs to the ATCase OTCase family
FTW19_25525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FTW19_25545	COG0012	GTP binding
FTW19_25550	COG3119	arylsulfatase activity
FTW19_25555	COG0436	Aminotransferase
FTW19_25565	COG0285	dihydrofolate synthase activity
FTW19_25575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FTW19_25600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FTW19_25605	COG0739	heme binding
FTW19_25620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FTW19_25630	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FTW19_25635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form