locus-tag	class	description
BW730_00010	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BW730_00025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BW730_00035	COG1082	Xylose isomerase domain protein TIM barrel
BW730_00040	COG0506	proline dehydrogenase activity
BW730_00055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BW730_00070	COG1648	precorrin-2 dehydrogenase activity
BW730_00070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BW730_00075	COG0406	alpha-ribazole phosphatase activity
BW730_00080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BW730_00085	COG0785	Cytochrome C biogenesis protein
BW730_00090	COG1333	cytochrome c biogenesis protein
BW730_00095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BW730_00105	COG0300	oxidoreductase activity
BW730_00125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BW730_00150	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BW730_00155	COG0456	acetyltransferase
BW730_00160	COG0745	RESPONSE REGULATOR receiver
BW730_00170	COG1490	D-aminoacyl-tRNA deacylase activity
BW730_00175	COG3485	protocatechuate 3,4-dioxygenase
BW730_00180	COG0354	folic acid binding
BW730_00195	COG1454	alcohol dehydrogenase
BW730_00215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BW730_00255	COG1609	Transcriptional regulator
BW730_00285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BW730_00285	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BW730_00285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BW730_00290	COG1461	Dihydroxyacetone kinase
BW730_00295	COG2376	Dihydroxyacetone kinase
BW730_00300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BW730_00310	COG2318	DinB family
BW730_00370	COG1028	Short-chain dehydrogenase reductase Sdr
BW730_00395	COG1846	Transcriptional regulator
BW730_00405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BW730_00420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BW730_00445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BW730_00455	COG0765	amino acid transport
BW730_00460	COG0765	amino acid transport
BW730_00465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BW730_00470	COG1126	abc transporter atp-binding protein
BW730_00500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BW730_00500	COG1648	precorrin-2 dehydrogenase activity
BW730_00510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BW730_00525	COG1129	ABC transporter
BW730_00530	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_00535	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_00560	COG2094	Belongs to the DNA glycosylase MPG family
BW730_00570	COG0436	Aminotransferase
BW730_00575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BW730_00580	COG0047	phosphoribosylformylglycinamidine synthase activity
BW730_00610	COG0673	inositol 2-dehydrogenase activity
BW730_00640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BW730_00650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BW730_00655	COG1027	Aspartate ammonia-lyase
BW730_00660	COG2234	aminopeptidase activity
BW730_00680	COG1609	Transcriptional regulator
BW730_00685	COG2182	Extracellular solute-binding protein
BW730_00695	COG3833	ABC-type maltose transport systems, permease component
BW730_00700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BW730_00755	COG3420	alginic acid biosynthetic process
BW730_00805	COG1140	nitrate reductase beta subunit
BW730_00810	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BW730_00830	COG0314	molybdopterin synthase activity
BW730_00835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BW730_00845	COG0315	cyclic pyranopterin monophosphate synthase activity
BW730_00850	COG2378	regulation of single-species biofilm formation
BW730_00880	COG0315	cyclic pyranopterin monophosphate synthase activity
BW730_00880	COG0521	Mo-molybdopterin cofactor biosynthetic process
BW730_00915	COG1136	(ABC) transporter
BW730_00915	COG0577	efflux transmembrane transporter activity
BW730_00935	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BW730_00950	COG0395	ABC-type sugar transport system, permease component
BW730_00955	COG0442	prolyl-tRNA aminoacylation
BW730_00985	COG2838	Isocitrate dehydrogenase
BW730_01030	COG1333	cytochrome c biogenesis protein
BW730_01035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BW730_01115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BW730_01125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BW730_01140	COG0667	Aldo Keto reductase
BW730_01145	COG1794	racemase activity, acting on amino acids and derivatives
BW730_01170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BW730_01190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BW730_01195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BW730_01200	COG1461	Dihydroxyacetone kinase
BW730_01220	COG4948	Mandelate Racemase Muconate Lactonizing
BW730_01225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BW730_01235	COG2226	methyltransferase
BW730_01240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BW730_01250	COG1169	isochorismate synthase
BW730_01255	COG0644	oxidoreductase
BW730_01265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BW730_01270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BW730_01275	COG0649	NAD binding
BW730_01285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BW730_01295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BW730_01300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BW730_01310	COG0713	ATP synthesis coupled electron transport
BW730_01325	COG1007	ATP synthesis coupled electron transport
BW730_01340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BW730_01345	COG2197	response regulator
BW730_01350	COG2909	trisaccharide binding
BW730_01360	COG0471	metal ion transport
BW730_01360	COG0490	domain, Protein
BW730_01385	COG0674	pyruvate-flavodoxin oxidoreductase activity
BW730_01385	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BW730_01390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BW730_01395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BW730_01405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BW730_01425	COG1666	GTP binding
BW730_01435	COG0813	purine-nucleoside phosphorylase activity
BW730_01455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BW730_01470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BW730_01480	COG1473	amidohydrolase
BW730_01485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BW730_01500	COG1672	PFAM Archaeal ATPase
BW730_01500	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BW730_01510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BW730_01525	COG0395	ABC-type sugar transport system, permease component
BW730_01570	COG1739	Uncharacterized protein family UPF0029
BW730_01590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BW730_01600	COG2205	protein histidine kinase activity
BW730_01605	COG0745	RESPONSE REGULATOR receiver
BW730_01640	COG1064	alcohol dehydrogenase
BW730_01755	COG1321	iron dependent repressor
BW730_01780	COG2132	Multicopper oxidase
BW730_01820	COG0785	Cytochrome C biogenesis protein
BW730_01840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BW730_01840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BW730_01880	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BW730_01975	COG0739	heme binding
BW730_01975	COG0741	lytic transglycosylase activity
BW730_01975	COG1196	nuclear chromosome segregation
BW730_02030	COG0629	single-stranded DNA binding
BW730_02105	COG1595	DNA-templated transcription, initiation
BW730_02110	COG0247	lactate metabolic process
BW730_02110	COG0277	FAD linked oxidase domain protein
BW730_02130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BW730_02140	COG1201	RNA secondary structure unwinding
BW730_02180	COG0395	ABC-type sugar transport system, permease component
BW730_02185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BW730_02190	COG0540	Belongs to the ATCase OTCase family
BW730_02195	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BW730_02285	COG1472	Belongs to the glycosyl hydrolase 3 family
BW730_02300	COG3654	unkown
BW730_02320	COG0544	peptidyl-prolyl cis-trans isomerase activity
BW730_02325	COG0628	permease
BW730_02330	COG0740	serine-type endopeptidase activity
BW730_02335	COG0740	serine-type endopeptidase activity
BW730_02345	COG4946	Tricorn protease homolog
BW730_02345	COG0793	Belongs to the peptidase S41A family
BW730_02360	COG1175	transmembrane transport
BW730_02370	COG1472	Belongs to the glycosyl hydrolase 3 family
BW730_02400	COG0525	valine-tRNA ligase activity
BW730_02420	COG0285	dihydrofolate synthase activity
BW730_02430	COG0105	UTP biosynthetic process
BW730_02455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BW730_02460	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW730_02460	COG0596	Alpha beta hydrolase
BW730_02465	COG4868	Belongs to the UPF0371 family
BW730_02470	COG2807	transmembrane transport
BW730_02490	COG0395	ABC-type sugar transport system, permease component
BW730_02495	COG1175	transmembrane transport
BW730_02520	COG1530	ribonuclease E activity
BW730_02525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BW730_02530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BW730_02540	COG2197	response regulator
BW730_02545	COG4585	Histidine kinase
BW730_02555	COG1131	(ABC) transporter
BW730_02570	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BW730_02590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BW730_02600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BW730_02645	COG0616	signal peptide processing
BW730_02655	COG0228	four-way junction DNA binding
BW730_02660	COG1837	Belongs to the UPF0109 family
BW730_02665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BW730_02670	COG0336	Belongs to the RNA methyltransferase TrmD family
BW730_02680	COG1053	succinate dehydrogenase
BW730_02685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BW730_02690	COG0335	large ribosomal subunit rRNA binding
BW730_02705	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BW730_02715	COG0792	nuclease activity
BW730_02720	COG0606	chelatase, subunit chli
BW730_02750	COG0577	efflux transmembrane transporter activity
BW730_02750	COG1136	(ABC) transporter
BW730_02770	COG2226	methyltransferase
BW730_02815	COG0395	ABC-type sugar transport system, permease component
BW730_02820	COG1175	transmembrane transport
BW730_02830	COG1609	Transcriptional regulator
BW730_02845	COG1129	ABC transporter
BW730_02850	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_02855	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_02890	COG0667	Aldo Keto reductase
BW730_02895	COG1968	undecaprenyl-diphosphatase activity
BW730_02915	COG0215	cysteine-tRNA ligase activity
BW730_02920	COG0140	phosphoribosyl-ATP diphosphatase activity
BW730_02925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BW730_02950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BW730_02955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BW730_02960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BW730_02970	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BW730_02975	COG0072	phenylalanine-tRNA ligase activity
BW730_02975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BW730_02980	COG2827	Endonuclease containing a URI domain
BW730_03035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BW730_03040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BW730_03045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BW730_03060	COG0165	Argininosuccinate lyase
BW730_03065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BW730_03120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BW730_03140	COG4974	Belongs to the 'phage' integrase family
BW730_03145	COG4552	Acetyltransferase involved in intracellular survival and related
BW730_03165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BW730_03185	COG2378	regulation of single-species biofilm formation
BW730_03200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BW730_03205	COG0805	protein transport
BW730_03220	COG4581	dead DEAH box helicase
BW730_03225	COG0107	imidazoleglycerol-phosphate synthase activity
BW730_03230	COG0537	adenosine 5'-monophosphoramidase activity
BW730_03245	COG0440	acetolactate synthase activity
BW730_03260	COG1063	alcohol dehydrogenase
BW730_03265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BW730_03270	COG1349	DNA-binding transcription factor activity
BW730_03290	COG1595	DNA-templated transcription, initiation
BW730_03295	COG2239	Acts as a magnesium transporter
BW730_03305	COG0473	3-isopropylmalate dehydrogenase activity
BW730_03310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BW730_03320	COG1266	CAAX protease self-immunity
BW730_03335	COG2375	cellular response to nickel ion
BW730_03340	COG1414	Transcriptional regulator
BW730_03345	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BW730_03350	COG0066	3-isopropylmalate dehydratase activity
BW730_03365	COG1505	serine-type exopeptidase activity
BW730_03375	COG0740	serine-type endopeptidase activity
BW730_03380	COG0740	serine-type endopeptidase activity
BW730_03400	COG1181	Belongs to the D-alanine--D-alanine ligase family
BW730_03420	COG1674	ftsk spoiiie
BW730_03425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BW730_03435	COG1546	Belongs to the CinA family
BW730_03435	COG1058	Belongs to the CinA family
BW730_03440	COG1396	sequence-specific DNA binding
BW730_03460	COG2137	regulation of response to DNA damage stimulus
BW730_03465	COG1418	mRNA catabolic process
BW730_03470	COG2017	converts alpha-aldose to the beta-anomer
BW730_03475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BW730_03485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BW730_03490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BW730_03495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BW730_03505	COG0366	Alpha amylase catalytic
BW730_03515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BW730_03520	COG2226	methyltransferase
BW730_03540	COG1028	Short-chain dehydrogenase reductase Sdr
BW730_03550	COG1063	alcohol dehydrogenase
BW730_03555	COG0656	L-ascorbic acid biosynthetic process
BW730_03565	COG1119	ATPase activity
BW730_03585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BW730_03585	COG0512	Glutamine amidotransferase of anthranilate synthase
BW730_03590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BW730_03600	COG0242	peptide deformylase activity
BW730_03605	COG4974	Belongs to the 'phage' integrase family
BW730_03610	COG0739	heme binding
BW730_03610	COG0741	lytic transglycosylase activity
BW730_03610	COG1196	nuclear chromosome segregation
BW730_03615	COG0052	Belongs to the universal ribosomal protein uS2 family
BW730_03620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BW730_03625	COG0528	UMP kinase activity
BW730_03630	COG0233	cytoplasmic translational termination
BW730_03635	COG0575	Belongs to the CDS family
BW730_03640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BW730_03645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BW730_03660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BW730_03665	COG0750	zinc metalloprotease
BW730_03670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BW730_03685	COG0442	prolyl-tRNA aminoacylation
BW730_03690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BW730_03695	COG0800	Aldolase
BW730_03705	COG2964	Protein conserved in bacteria
BW730_03720	COG1653	transport
BW730_03725	COG1175	transmembrane transport
BW730_03745	COG0779	Required for maturation of 30S ribosomal subunits
BW730_03770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BW730_03775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BW730_03780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BW730_03795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BW730_03800	COG1879	ABC-type sugar transport system periplasmic component
BW730_03810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_03815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_03825	COG1185	polyribonucleotide nucleotidyltransferase activity
BW730_03830	COG2197	response regulator
BW730_03845	COG1879	ABC-type sugar transport system periplasmic component
BW730_03855	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_03860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BW730_03895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BW730_03900	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BW730_03905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BW730_03915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BW730_03925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BW730_03930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BW730_03940	COG0406	alpha-ribazole phosphatase activity
BW730_03960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BW730_03975	COG0181	hydroxymethylbilane synthase activity
BW730_03985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BW730_03990	COG0181	hydroxymethylbilane synthase activity
BW730_04030	COG0601	transmembrane transport
BW730_04040	COG0747	negative chemotaxis
BW730_04045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BW730_04080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BW730_04085	COG0446	pyridine nucleotide-disulphide oxidoreductase
BW730_04090	COG1937	Protein conserved in bacteria
BW730_04110	COG2070	2-Nitropropane dioxygenase
BW730_04120	COG0659	secondary active sulfate transmembrane transporter activity
BW730_04135	COG1733	regulation of RNA biosynthetic process
BW730_04140	COG2910	NAD(P)H-binding
BW730_04155	COG0025	NhaP-type Na H and K H
BW730_04160	COG2855	membrane
BW730_04215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BW730_04220	COG0495	leucyl-tRNA aminoacylation
BW730_04235	COG5290	Psort location Cytoplasmic, score
BW730_04245	COG1555	photosystem II stabilization
BW730_04245	COG1596	polysaccharide export
BW730_04250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BW730_04285	COG0673	inositol 2-dehydrogenase activity
BW730_04295	COG1595	DNA-templated transcription, initiation
BW730_04310	COG0268	Binds directly to 16S ribosomal RNA
BW730_04315	COG0481	GTPase activity
BW730_04320	COG1643	Atp-dependent helicase
BW730_04325	COG0395	ABC-type sugar transport system, permease component
BW730_04330	COG1175	transmembrane transport
BW730_04350	COG1725	Transcriptional regulator
BW730_04355	COG1131	(ABC) transporter
BW730_04375	COG1609	Transcriptional regulator
BW730_04400	COG0395	ABC-type sugar transport system, permease component
BW730_04405	COG3507	Belongs to the glycosyl hydrolase 43 family
BW730_04415	COG1609	Transcriptional regulator
BW730_04425	COG2160	L-arabinose isomerase activity
BW730_04440	COG3534	alpha-L-arabinofuranosidase
BW730_04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BW730_04455	COG1420	regulation of RNA biosynthetic process
BW730_04460	COG0484	heat shock protein binding
BW730_04470	COG0343	queuine tRNA-ribosyltransferase activity
BW730_04490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BW730_04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BW730_04515	COG1175	transmembrane transport
BW730_04520	COG0395	ABC-type sugar transport system, permease component
BW730_04525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BW730_04530	COG1408	metallophosphoesterase
BW730_04545	COG2826	transposase and inactivated derivatives, IS30 family
BW730_04550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BW730_04555	COG1381	Involved in DNA repair and RecF pathway recombination
BW730_04565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BW730_04570	COG1121	(ABC) transporter
BW730_04575	COG0803	Belongs to the bacterial solute-binding protein 9 family
BW730_04600	COG0277	FAD linked oxidase domain protein
BW730_04640	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BW730_04660	COG3655	Transcriptional regulator
BW730_04665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BW730_04695	COG0714	Associated with various cellular activities
BW730_04705	COG2304	oxidoreductase activity
BW730_04710	COG2304	oxidoreductase activity
BW730_04715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BW730_04735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BW730_04740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BW730_04745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BW730_04765	COG1115	amino acid carrier protein
BW730_04775	COG1648	precorrin-2 dehydrogenase activity
BW730_04775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BW730_04780	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BW730_04780	COG1796	DNA polymerase
BW730_04785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BW730_04805	COG0574	Belongs to the PEP-utilizing enzyme family
BW730_04805	COG3848	Pyruvate phosphate dikinase
BW730_04860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BW730_04865	COG2884	Cell division ATP-binding protein ftsE
BW730_04875	COG0741	lytic transglycosylase activity
BW730_04875	COG1196	nuclear chromosome segregation
BW730_04875	COG0739	heme binding
BW730_04880	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BW730_04895	COG1678	Uncharacterized ACR, COG1678
BW730_04915	COG0745	RESPONSE REGULATOR receiver
BW730_04920	COG5002	protein histidine kinase activity
BW730_04930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BW730_04935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BW730_04960	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BW730_04985	COG0613	PHP domain protein
BW730_04995	COG0513	Belongs to the DEAD box helicase family
BW730_05015	COG1793	dna ligase
BW730_05015	COG3285	dna ligase
BW730_05030	COG0210	DNA helicase
BW730_05045	COG0187	DNA topoisomerase II activity
BW730_05050	COG1556	Lactate utilization protein
BW730_05055	COG1139	Iron-sulfur cluster binding protein
BW730_05060	COG0247	lactate metabolic process
BW730_05065	COG1620	l-lactate permease
BW730_05070	COG1802	Transcriptional regulator
BW730_05080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BW730_05105	COG1435	thymidine kinase activity
BW730_05130	COG0756	dUTP diphosphatase activity
BW730_05150	COG0569	domain protein
BW730_05155	COG0531	amino acid
BW730_05160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BW730_05170	COG0477	Major facilitator Superfamily
BW730_05180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BW730_05185	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BW730_05190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BW730_05200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW730_05260	COG5006	permease, DMT superfamily
BW730_05265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BW730_05280	COG1024	Enoyl-CoA hydratase
BW730_05285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BW730_05300	COG0438	transferase activity, transferring glycosyl groups
BW730_05345	COG1295	ribonuclease BN
BW730_05365	COG0656	L-ascorbic acid biosynthetic process
BW730_05370	COG0009	L-threonylcarbamoyladenylate synthase
BW730_05385	COG0318	PFAM AMP-dependent synthetase and ligase
BW730_05400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW730_05400	COG2190	(PTS) system
BW730_05400	COG1263	PTS System
BW730_05410	COG0667	Aldo Keto reductase
BW730_05430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BW730_05435	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BW730_05450	COG3030	protein affecting phage T7 exclusion by the F plasmid
BW730_05455	COG1216	Glycosyl transferase, family 2
BW730_05460	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BW730_05465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BW730_05470	COG2813	Specifically methylates the guanine in position
BW730_05470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BW730_05475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BW730_05500	COG0395	ABC-type sugar transport system, permease component
BW730_05505	COG1175	transmembrane transport
BW730_05510	COG1653	transport
BW730_05515	COG0647	UMP catabolic process
BW730_05550	COG2409	Drug exporters of the RND superfamily
BW730_05555	COG4585	Histidine kinase
BW730_05560	COG2197	response regulator
BW730_05580	COG0545	Peptidyl-prolyl cis-trans isomerase
BW730_05585	COG1621	beta-fructofuranosidase activity
BW730_05590	COG0395	ABC-type sugar transport system, permease component
BW730_05595	COG1175	transmembrane transport
BW730_05605	COG1609	Transcriptional regulator
BW730_05660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BW730_05735	COG4977	sequence-specific DNA binding
BW730_05735	COG1917	Cupin 2, conserved barrel domain protein
BW730_05785	COG0739	heme binding
BW730_05785	COG1196	nuclear chromosome segregation
BW730_05785	COG0741	lytic transglycosylase activity
BW730_05850	COG4974	Belongs to the 'phage' integrase family
BW730_05860	COG0500	methyltransferase
BW730_05875	COG1160	GTP binding
BW730_05885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BW730_05895	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BW730_05900	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BW730_05915	COG1410	methionine synthase
BW730_05915	COG0646	methionine synthase
BW730_05930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BW730_05935	COG2801	Transposase and inactivated derivatives
BW730_05935	COG3415	Transposase
BW730_05950	COG3189	MarR family transcriptional regulator
BW730_05970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BW730_05980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BW730_05985	COG1758	RNA polymerase activity
BW730_05990	COG0194	GDP metabolic process
BW730_06000	COG0284	orotidine-5'-phosphate decarboxylase activity
BW730_06005	COG0167	dihydroorotate dehydrogenase activity
BW730_06010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BW730_06015	COG0505	Belongs to the CarA family
BW730_06020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BW730_06025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BW730_06035	COG4585	Histidine kinase
BW730_06040	COG2197	response regulator
BW730_06055	COG1690	Belongs to the RtcB family
BW730_06065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BW730_06070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BW730_06080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BW730_06095	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BW730_06100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BW730_06140	COG1263	PTS System
BW730_06140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW730_06140	COG2190	(PTS) system
BW730_06150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BW730_06170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BW730_06175	COG1196	nuclear chromosome segregation
BW730_06180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BW730_06195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BW730_06200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BW730_06205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BW730_06210	COG1862	Preprotein translocase
BW730_06225	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BW730_06230	COG0217	transcriptional regulatory protein
BW730_06260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BW730_06265	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BW730_06270	COG0131	Imidazoleglycerol-phosphate dehydratase
BW730_06275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BW730_06280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BW730_06290	COG0587	DNA-directed DNA polymerase activity
BW730_06295	COG0569	domain protein
BW730_06295	COG2985	domain, Protein
BW730_06325	COG0395	ABC-type sugar transport system, permease component
BW730_06330	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BW730_06340	COG0698	ribose 5-phosphate isomerase
BW730_06350	COG0070	glutamate synthase
BW730_06350	COG0067	glutamate synthase
BW730_06350	COG0069	glutamate synthase activity
BW730_06370	COG0159	tryptophan synthase activity
BW730_06395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BW730_06400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BW730_06405	COG2258	MOSC domain
BW730_06415	COG0133	tryptophan synthase activity
BW730_06440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BW730_06445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BW730_06450	COG0154	amidase activity
BW730_06455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BW730_06460	COG0596	Alpha beta hydrolase
BW730_06490	COG0366	Alpha amylase catalytic
BW730_06570	COG0596	Alpha beta hydrolase
BW730_06575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BW730_06600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BW730_06605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BW730_06615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BW730_06620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BW730_06625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BW730_06650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BW730_06660	COG0009	L-threonylcarbamoyladenylate synthase
BW730_06665	COG2890	protein-(glutamine-N5) methyltransferase activity
BW730_06670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BW730_06675	COG0254	rRNA binding
BW730_06690	COG0083	homoserine kinase activity
BW730_06695	COG0460	homoserine dehydrogenase
BW730_06720	COG0567	Dehydrogenase, E1 component
BW730_06720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW730_06725	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BW730_06755	COG2135	peptidase activity
BW730_06770	COG1162	GTPase activity
BW730_06775	COG0483	inositol monophosphate 1-phosphatase activity
BW730_06780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BW730_06785	COG4608	Belongs to the ABC transporter superfamily
BW730_06790	COG0444	Belongs to the ABC transporter superfamily
BW730_06795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BW730_06805	COG0747	negative chemotaxis
BW730_06810	COG4129	membrane
BW730_06830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BW730_06845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BW730_06855	COG2376	Dihydroxyacetone kinase
BW730_06880	COG2205	protein histidine kinase activity
BW730_06915	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BW730_06960	COG2255	four-way junction helicase activity
BW730_07015	COG1115	amino acid carrier protein
BW730_07020	COG0667	Aldo Keto reductase
BW730_07040	COG1615	UPF0182 protein
BW730_07050	COG3480	Lon protease (S16) C-terminal proteolytic domain
BW730_07080	COG1074	ATP-dependent DNA helicase activity
BW730_07095	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BW730_07105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BW730_07115	COG1946	Acyl-CoA thioesterase
BW730_07120	COG1643	Atp-dependent helicase
BW730_07160	COG1648	precorrin-2 dehydrogenase activity
BW730_07160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BW730_07165	COG1797	cobyrinic acid a,c-diamide synthase activity
BW730_07170	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BW730_07185	COG0395	ABC-type sugar transport system, permease component
BW730_07195	COG1653	transport
BW730_07200	COG1609	Transcriptional regulator
BW730_07220	COG0310	cobalt ion transport
BW730_07235	COG1648	precorrin-2 dehydrogenase activity
BW730_07235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BW730_07255	COG4989	oxidoreductase activity
BW730_07260	COG1492	cobalamin metabolic process
BW730_07265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BW730_07270	COG0406	alpha-ribazole phosphatase activity
BW730_07290	COG0129	dihydroxy-acid dehydratase activity
BW730_07300	COG5426	von Willebrand factor, type A
BW730_07320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BW730_07325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BW730_07330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BW730_07335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BW730_07345	COG2217	Heavy metal translocating P-type atpase
BW730_07350	COG0488	(ABC) transporter
BW730_07355	COG2197	response regulator
BW730_07370	COG2267	carboxylic ester hydrolase activity
BW730_07380	COG0822	iron-sulfur transferase activity
BW730_07385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BW730_07390	COG0396	ATPase activity
BW730_07425	COG1612	heme a metabolic process
BW730_07460	COG1136	(ABC) transporter
BW730_07490	COG0109	protoheme IX farnesyltransferase activity
BW730_07505	COG0363	glucosamine-6-phosphate deaminase activity
BW730_07520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BW730_07525	COG0149	triose-phosphate isomerase activity
BW730_07530	COG0126	phosphoglycerate kinase activity
BW730_07535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BW730_07540	COG1481	regulation of sporulation
BW730_07550	COG1660	Displays ATPase and GTPase activities
BW730_07555	COG3104	oligopeptide transport
BW730_07565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BW730_07570	COG1122	ATPase activity
BW730_07575	COG1268	BioY protein
BW730_07580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BW730_07585	COG0583	DNA-binding transcription factor activity
BW730_07605	COG0395	ABC-type sugar transport system, permease component
BW730_07610	COG0322	excinuclease ABC activity
BW730_07620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BW730_07640	COG0556	nucleotide-excision repair
BW730_07645	COG0475	glutathione-regulated potassium exporter activity
BW730_07645	COG0589	response to stress
BW730_07660	COG0509	glycine decarboxylation via glycine cleavage system
BW730_07665	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BW730_07665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BW730_07675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BW730_07680	COG0477	Major facilitator Superfamily
BW730_07690	COG0237	dephospho-CoA kinase activity
BW730_07715	COG1175	transmembrane transport
BW730_07720	COG1653	transport
BW730_07725	COG1609	Transcriptional regulator
BW730_07735	COG0539	negative regulation of cytoplasmic translation
BW730_07750	COG2050	protein possibly involved in aromatic compounds catabolism
BW730_07765	COG0469	pyruvate kinase activity
BW730_07795	COG1799	cell septum assembly
BW730_07810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BW730_07820	COG0772	Belongs to the SEDS family
BW730_07825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BW730_07830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BW730_07835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BW730_07845	COG0768	penicillin binding
BW730_07855	COG0275	rRNA processing
BW730_07860	COG2001	Belongs to the MraZ family
BW730_07865	COG0714	Associated with various cellular activities
BW730_07930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BW730_07930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BW730_07935	COG3973	AAA domain
BW730_07960	COG0515	serine threonine protein kinase
BW730_07960	COG2815	serine threonine protein kinase
BW730_07965	COG0515	serine threonine protein kinase
BW730_07965	COG2815	serine threonine protein kinase
BW730_07970	COG3250	beta-galactosidase activity
BW730_07990	COG1609	Transcriptional regulator
BW730_08000	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BW730_08010	COG2197	response regulator
BW730_08035	COG0280	phosphate acetyltransferase
BW730_08035	COG0857	belongs to the CobB CobQ family
BW730_08050	COG4820	ethanolamine utilization protein (EutJ)
BW730_08065	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BW730_08070	COG1454	alcohol dehydrogenase
BW730_08070	COG1012	belongs to the aldehyde dehydrogenase family
BW730_08075	COG4816	utilization protein
BW730_08080	COG4302	ethanolamine ammonia-lyase activity
BW730_08085	COG4303	Ethanolamine ammonia lyase large subunit
BW730_08095	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BW730_08130	COG0088	Forms part of the polypeptide exit tunnel
BW730_08135	COG3214	Protein conserved in bacteria
BW730_08155	COG1845	cytochrome c oxidase, subunit III
BW730_08165	COG0723	plastoquinol--plastocyanin reductase activity
BW730_08175	COG3831	ATPase activity
BW730_08180	COG0714	Associated with various cellular activities
BW730_08215	COG1191	sigma factor activity
BW730_08225	COG0673	inositol 2-dehydrogenase activity
BW730_08235	COG0745	RESPONSE REGULATOR receiver
BW730_08240	COG1840	ABC-type Fe3 transport system, periplasmic component
BW730_08245	COG4149	molybdate abc transporter
BW730_08250	COG3842	ATPase activity
BW730_08285	COG4585	Histidine kinase
BW730_08290	COG2197	response regulator
BW730_08295	COG4152	abc transporter atp-binding protein
BW730_08300	COG1668	transmembrane transport
BW730_08310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BW730_08315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BW730_08370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BW730_08375	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW730_08390	COG0321	lipoyl(octanoyl) transferase activity
BW730_08395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BW730_08405	COG0488	(ABC) transporter
BW730_08415	COG0534	Mate efflux family protein
BW730_08425	COG1012	belongs to the aldehyde dehydrogenase family
BW730_08435	COG2723	6-phospho-beta-galactosidase activity
BW730_08460	COG1136	(ABC) transporter
BW730_08480	COG0656	L-ascorbic acid biosynthetic process
BW730_08500	COG0174	glutamine synthetase
BW730_08505	COG2409	Drug exporters of the RND superfamily
BW730_08515	COG0604	alcohol dehydrogenase
BW730_08530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BW730_08535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BW730_08545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BW730_08555	COG0174	glutamine synthetase
BW730_08570	COG1595	DNA-templated transcription, initiation
BW730_08640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BW730_08645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BW730_08650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BW730_08675	COG3304	Inner membrane component domain
BW730_08680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BW730_08685	COG0101	tRNA pseudouridine synthase activity
BW730_08690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BW730_08700	COG2755	lipolytic protein G-D-S-L family
BW730_08700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BW730_08720	COG1609	Transcriptional regulator
BW730_08725	COG1116	anion transmembrane transporter activity
BW730_08730	COG4120	Belongs to the binding-protein-dependent transport system permease family
BW730_08740	COG0203	ribosomal protein L17
BW730_08745	COG0202	RNA polymerase activity
BW730_08750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BW730_08755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BW730_08760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BW730_08765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BW730_08770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BW730_08780	COG3459	Glycosyltransferase 36 associated
BW730_08785	COG1609	Transcriptional regulator
BW730_08795	COG1175	transmembrane transport
BW730_08800	COG0395	ABC-type sugar transport system, permease component
BW730_08830	COG0024	Methionine aminopeptidase
BW730_08835	COG0563	adenylate kinase activity
BW730_08840	COG0201	protein transport
BW730_08850	COG1841	ribosomal large subunit assembly
BW730_08855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BW730_08860	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BW730_08865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BW730_08870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BW730_08875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BW730_08880	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BW730_08885	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BW730_08890	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BW730_08900	COG1950	PFAM Membrane protein of
BW730_08915	COG1653	transport
BW730_08920	COG0366	Alpha amylase catalytic
BW730_08925	COG1609	Transcriptional regulator
BW730_08930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BW730_08935	COG0255	Belongs to the universal ribosomal protein uL29 family
BW730_08940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BW730_08945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BW730_08950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BW730_08955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BW730_08960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BW730_08965	COG0089	rRNA binding
BW730_08970	COG0088	Forms part of the polypeptide exit tunnel
BW730_08975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BW730_08980	COG0051	transcription antitermination factor activity, RNA binding
BW730_08995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BW730_09010	COG0494	nUDIX hydrolase
BW730_09060	COG0435	Glutathione S-transferase
BW730_09080	COG2837	iron assimilation
BW730_09085	COG0281	malic enzyme
BW730_09100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BW730_09125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BW730_09135	COG0049	tRNA binding
BW730_09140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BW730_09150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BW730_09160	COG0222	ribosome binding
BW730_09165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BW730_09180	COG0765	amino acid transport
BW730_09185	COG1126	abc transporter atp-binding protein
BW730_09195	COG0395	ABC-type sugar transport system, permease component
BW730_09205	COG1653	transport
BW730_09210	COG1609	Transcriptional regulator
BW730_09215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BW730_09220	COG0081	regulation of translation
BW730_09225	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BW730_09230	COG0250	Participates in transcription elongation, termination and antitermination
BW730_09250	COG1132	(ABC) transporter
BW730_09255	COG1132	(ABC) transporter
BW730_09260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BW730_09265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BW730_09270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BW730_09275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BW730_09285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BW730_09335	COG0515	serine threonine protein kinase
BW730_09335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BW730_09360	COG2835	tetraacyldisaccharide 4'-kinase activity
BW730_09405	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BW730_09405	COG0662	Cupin 2, conserved barrel domain protein
BW730_09430	COG1316	TRANSCRIPTIONal
BW730_09435	COG1316	TRANSCRIPTIONal
BW730_09465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BW730_09475	COG0424	maF-like protein
BW730_09485	COG1595	DNA-templated transcription, initiation
BW730_09505	COG4770	biotin carboxylase activity
BW730_09515	COG1609	Transcriptional regulator
BW730_09530	COG1175	transmembrane transport
BW730_09555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BW730_09570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BW730_09600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BW730_09610	COG3012	SEC-C Motif Domain Protein
BW730_09635	COG1175	transmembrane transport
BW730_09640	COG0395	ABC-type sugar transport system, permease component
BW730_09655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BW730_09690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BW730_09715	COG1744	ABC transporter substrate-binding protein PnrA-like
BW730_09725	COG1253	flavin adenine dinucleotide binding
BW730_09740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BW730_09745	COG0039	L-malate dehydrogenase activity
BW730_09760	COG1486	melibiose metabolic process
BW730_09775	COG1175	transmembrane transport
BW730_09780	COG0395	ABC-type sugar transport system, permease component
BW730_09790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BW730_09800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BW730_09805	COG0138	bifunctional purine biosynthesis protein purh
BW730_09830	COG0045	succinate-CoA ligase (ADP-forming) activity
BW730_09845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BW730_09865	COG0395	ABC-type sugar transport system, permease component
BW730_09870	COG1175	transmembrane transport
BW730_09890	COG2197	response regulator
BW730_09935	COG1131	(ABC) transporter
BW730_09945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BW730_09960	COG0287	Prephenate dehydrogenase
BW730_09960	COG1605	Chorismate mutase
BW730_09965	COG0516	GMP reductase activity
BW730_09995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BW730_10020	COG0210	DNA helicase
BW730_10025	COG0459	protein refolding
BW730_10030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BW730_10040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BW730_10060	COG3845	ABC transporter
BW730_10095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BW730_10100	COG0601	transmembrane transport
BW730_10105	COG4166	transmembrane transport
BW730_10110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BW730_10125	COG0802	atpase or kinase
BW730_10130	COG0513	Belongs to the DEAD box helicase family
BW730_10145	COG0736	holo-[acyl-carrier-protein] synthase activity
BW730_10155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BW730_10160	COG1072	(Pantothenic acid kinase))
BW730_10165	COG2860	membrane
BW730_10190	COG2239	Acts as a magnesium transporter
BW730_10210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BW730_10220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BW730_10235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BW730_10245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BW730_10250	COG0297	glycogen (starch) synthase activity
BW730_10265	COG1611	Belongs to the LOG family
BW730_10270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BW730_10290	COG1305	Transglutaminase-like
BW730_10335	COG2171	N-acyltransferase activity
BW730_10365	COG0616	signal peptide processing
BW730_10370	COG2826	transposase and inactivated derivatives, IS30 family
BW730_10385	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BW730_10420	COG1335	isochorismatase
BW730_10430	COG0559	Belongs to the binding-protein-dependent transport system permease family
BW730_10440	COG0411	ABC transporter
BW730_10445	COG0410	ABC transporter
BW730_10450	COG0517	IMP dehydrogenase activity
BW730_10475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW730_10480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW730_10490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BW730_10495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW730_10495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW730_10500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW730_10515	COG0598	Magnesium transport protein CorA
BW730_10550	COG1045	serine acetyltransferase
BW730_10565	COG1940	carbohydrate kinase activity
BW730_10570	COG0395	ABC-type sugar transport system, permease component
BW730_10585	COG1940	carbohydrate kinase activity
BW730_10620	COG1230	cation diffusion facilitator family transporter
BW730_10675	COG2226	methyltransferase
BW730_10685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BW730_10715	COG0456	acetyltransferase
BW730_10735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BW730_10755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BW730_10810	COG1660	Displays ATPase and GTPase activities
BW730_10850	COG0012	GTP binding
BW730_10875	COG1362	aminopeptidase activity
BW730_10885	COG1322	Protein conserved in bacteria
BW730_10895	COG3693	PFAM glycoside hydrolase, family 10
BW730_10900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BW730_10910	COG0561	phosphatase activity
BW730_10915	COG1570	exodeoxyribonuclease VII activity
BW730_10920	COG1722	exodeoxyribonuclease VII activity
BW730_10930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BW730_10945	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BW730_10965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BW730_10985	COG0666	response to abiotic stimulus
BW730_11005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BW730_11015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BW730_11050	COG0395	ABC-type sugar transport system, permease component
BW730_11055	COG1175	transmembrane transport
BW730_11070	COG1609	Transcriptional regulator
BW730_11080	COG1254	Belongs to the acylphosphatase family
BW730_11105	COG0494	nUDIX hydrolase
BW730_11115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BW730_11125	COG1793	dna ligase
BW730_11145	COG2268	Band 7 protein
BW730_11155	COG0745	RESPONSE REGULATOR receiver
BW730_11205	COG0148	phosphopyruvate hydratase activity
BW730_11210	COG3956	TIGRFAM MazG family protein
BW730_11230	COG0193	aminoacyl-tRNA hydrolase activity
BW730_11235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BW730_11240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BW730_11245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BW730_11245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BW730_11250	COG1609	Transcriptional regulator
BW730_11260	COG1070	Carbohydrate kinase
BW730_11270	COG0577	efflux transmembrane transporter activity
BW730_11270	COG1136	(ABC) transporter
BW730_11275	COG1136	(ABC) transporter
BW730_11290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BW730_11295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BW730_11310	COG2818	Glycosylase
BW730_11320	COG1846	Transcriptional regulator
BW730_11325	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BW730_11330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BW730_11335	COG0084	hydrolase, TatD family'
BW730_11355	COG2233	PERMEase
BW730_11360	COG1940	carbohydrate kinase activity
BW730_11405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BW730_11420	COG2217	Heavy metal translocating P-type atpase
BW730_11435	COG3507	Belongs to the glycosyl hydrolase 43 family
BW730_11445	COG2723	6-phospho-beta-galactosidase activity
BW730_11450	COG4172	Belongs to the ABC transporter superfamily
BW730_11460	COG0601	transmembrane transport
BW730_11505	COG1970	mechanosensitive ion channel activity
BW730_11590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BW730_11595	COG2226	methyltransferase
BW730_11600	COG1321	iron dependent repressor
BW730_11615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BW730_11630	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BW730_11635	COG2252	PERMEase
BW730_11645	COG1278	Cold shock
BW730_11650	COG0363	glucosamine-6-phosphate deaminase activity
BW730_11680	COG0459	protein refolding
BW730_11730	COG2197	response regulator
BW730_11740	COG3842	ATPase activity
BW730_11745	COG0626	cystathionine gamma-synthase activity
BW730_11765	COG1929	Belongs to the glycerate kinase type-1 family
BW730_11770	COG1609	Transcriptional regulator
BW730_11785	COG0673	inositol 2-dehydrogenase activity
BW730_11805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BW730_11825	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BW730_11830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BW730_11835	COG1329	Transcriptional regulator
BW730_11865	COG0726	polysaccharide deacetylase
BW730_11870	COG0588	phosphoglycerate mutase activity
BW730_11875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BW730_11880	COG1028	Short-chain dehydrogenase reductase Sdr
BW730_11885	COG4948	Mandelate Racemase Muconate Lactonizing
BW730_11890	COG3833	ABC-type maltose transport systems, permease component
BW730_11955	COG1609	Transcriptional regulator
BW730_11960	COG0246	Mannitol dehydrogenase
BW730_11985	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_11990	COG1129	ABC transporter
BW730_12005	COG1051	belongs to the nudix hydrolase family
BW730_12025	COG1028	Short-chain dehydrogenase reductase Sdr
BW730_12035	COG0022	dehydrogenase e1 component
BW730_12040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BW730_12045	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW730_12050	COG1349	DNA-binding transcription factor activity
BW730_12090	COG1595	DNA-templated transcription, initiation
BW730_12125	COG3958	Transketolase
BW730_12130	COG3959	Transketolase, thiamine diphosphate binding domain
BW730_12135	COG1082	Xylose isomerase domain protein TIM barrel
BW730_12140	COG1879	ABC-type sugar transport system periplasmic component
BW730_12145	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_12150	COG1129	ABC transporter
BW730_12160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BW730_12170	COG1609	Transcriptional regulator
BW730_12175	COG1070	Carbohydrate kinase
BW730_12180	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BW730_12190	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_12215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BW730_12225	COG1716	ATPase activity
BW730_12245	COG0768	penicillin binding
BW730_12250	COG0515	serine threonine protein kinase
BW730_12270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BW730_12275	COG0393	Putative heavy-metal-binding
BW730_12280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BW730_12335	COG2514	catechol 2,3-dioxygenase activity
BW730_12340	COG2326	polyphosphate kinase activity
BW730_12345	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BW730_12355	COG1271	oxidase subunit
BW730_12360	COG1294	oxidase, subunit
BW730_12370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BW730_12385	COG1609	Transcriptional regulator
BW730_12395	COG1175	transmembrane transport
BW730_12400	COG0395	ABC-type sugar transport system, permease component
BW730_12425	COG0114	fumarate hydratase activity
BW730_12430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BW730_12440	COG1937	Protein conserved in bacteria
BW730_12445	COG0305	Participates in initiation and elongation during chromosome replication
BW730_12475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BW730_12480	COG1742	UPF0060 membrane protein
BW730_12495	COG3764	Sortase (surface protein transpeptidase)
BW730_12525	COG1397	ADP-ribosylglycohydrolase
BW730_12530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BW730_12535	COG0686	Belongs to the AlaDH PNT family
BW730_12590	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_12595	COG1129	ABC transporter
BW730_12610	COG0006	proline dipeptidase activity
BW730_12620	COG1393	Belongs to the ArsC family
BW730_12630	COG1120	ATPase activity
BW730_12635	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BW730_12640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BW730_12735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BW730_12745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BW730_12760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BW730_12785	COG1595	DNA-templated transcription, initiation
BW730_12845	COG1472	Belongs to the glycosyl hydrolase 3 family
BW730_12870	COG2066	Belongs to the glutaminase family
BW730_12890	COG0745	RESPONSE REGULATOR receiver
BW730_12895	COG5002	protein histidine kinase activity
BW730_12905	COG3158	transport of potassium into the cell
BW730_12910	COG0439	Biotin carboxylase
BW730_12950	COG1132	(ABC) transporter
BW730_12955	COG0641	radical SAM
BW730_12985	COG4213	ABC transporter substrate-binding protein
BW730_12995	COG4214	carbohydrate transport
BW730_13010	COG0318	PFAM AMP-dependent synthetase and ligase
BW730_13025	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BW730_13060	COG1064	alcohol dehydrogenase
BW730_13105	COG1388	LysM domain
BW730_13130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BW730_13140	COG2197	response regulator
BW730_13190	COG3655	Transcriptional regulator
BW730_13215	COG0346	lactoylglutathione lyase activity
BW730_13220	COG0402	S-adenosylhomocysteine deaminase activity
BW730_13225	COG1846	Transcriptional regulator
BW730_13240	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BW730_13260	COG1733	regulation of RNA biosynthetic process
BW730_13310	COG0513	Belongs to the DEAD box helicase family
BW730_13340	COG0395	ABC-type sugar transport system, permease component
BW730_13360	COG4172	Belongs to the ABC transporter superfamily
BW730_13365	COG4608	Belongs to the ABC transporter superfamily
BW730_13415	COG0371	Dehydrogenase
BW730_13420	COG0647	UMP catabolic process
BW730_13430	COG1840	ABC-type Fe3 transport system, periplasmic component
BW730_13440	COG3842	ATPase activity
BW730_13445	COG2390	Transcriptional regulator
BW730_13455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BW730_13465	COG0300	oxidoreductase activity
BW730_13495	COG4585	Histidine kinase
BW730_13515	COG0420	3'-5' exonuclease activity
BW730_13520	COG0419	ATPase involved in DNA repair
BW730_13535	COG3842	ATPase activity
BW730_13550	COG1840	ABC-type Fe3 transport system, periplasmic component
BW730_13555	COG1764	response to oxidative stress
BW730_13560	COG1940	carbohydrate kinase activity
BW730_13565	COG3345	alpha-galactosidase
BW730_13580	COG1278	Cold shock
BW730_13585	COG0395	ABC-type sugar transport system, permease component
BW730_13590	COG1175	transmembrane transport
BW730_13630	COG2226	methyltransferase
BW730_13660	COG0242	peptide deformylase activity
BW730_13670	COG0714	Associated with various cellular activities
BW730_13710	COG1132	(ABC) transporter
BW730_13720	COG0577	efflux transmembrane transporter activity
BW730_13720	COG1136	(ABC) transporter
BW730_13830	COG1090	epimerase
BW730_13835	COG0705	Rhomboid family
BW730_13835	COG0457	Tetratricopeptide repeat
BW730_13850	COG2814	Major facilitator Superfamily
BW730_13880	COG2826	transposase and inactivated derivatives, IS30 family
BW730_13885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BW730_13895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BW730_13905	COG2188	Transcriptional regulator
BW730_13915	COG0673	inositol 2-dehydrogenase activity
BW730_13920	COG1414	Transcriptional regulator
BW730_13940	COG0673	inositol 2-dehydrogenase activity
BW730_13945	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_13950	COG1129	ABC transporter
BW730_13960	COG2115	Belongs to the xylose isomerase family
BW730_13965	COG1940	carbohydrate kinase activity
BW730_13970	COG0673	inositol 2-dehydrogenase activity
BW730_13975	COG0673	inositol 2-dehydrogenase activity
BW730_13985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BW730_14010	COG1082	Xylose isomerase domain protein TIM barrel
BW730_14015	COG0673	inositol 2-dehydrogenase activity
BW730_14020	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_14025	COG1129	ABC transporter
BW730_14030	COG1879	ABC-type sugar transport system periplasmic component
BW730_14045	COG1082	Xylose isomerase domain protein TIM barrel
BW730_14050	COG3962	Belongs to the TPP enzyme family
BW730_14055	COG3718	enzyme involved in inositol metabolism
BW730_14080	COG0673	inositol 2-dehydrogenase activity
BW730_14140	COG5564	TIM-barrel signal transduction protein
BW730_14150	COG1309	transcriptional regulator
BW730_14155	COG1131	(ABC) transporter
BW730_14160	COG3559	Exporter of polyketide antibiotics
BW730_14165	COG3177	Filamentation induced by cAMP protein fic
BW730_14170	COG1715	Restriction endonuclease
BW730_14195	COG0732	type I restriction modification DNA specificity domain
BW730_14205	COG3328	transposase activity
BW730_14240	COG5290	Psort location Cytoplasmic, score
BW730_14255	COG3328	transposase activity
BW730_14270	COG3547	Transposase (IS116 IS110 IS902 family)
BW730_14375	COG1609	Transcriptional regulator
BW730_14385	COG3842	ATPase activity
BW730_14395	COG1840	ABC-type Fe3 transport system, periplasmic component
BW730_14435	COG1874	Beta-galactosidase
BW730_14450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BW730_14455	COG1335	isochorismatase
BW730_14460	COG2390	Transcriptional regulator
BW730_14490	COG1181	Belongs to the D-alanine--D-alanine ligase family
BW730_14510	COG1192	Involved in chromosome partitioning
BW730_14525	COG0357	Ribosomal RNA small subunit methyltransferase G
BW730_14535	COG0706	membrane insertase activity
BW730_14540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BW730_14545	COG0594	ribonuclease P activity
BW730_14550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BW730_14555	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BW730_14560	COG2226	methyltransferase
BW730_14575	COG1136	(ABC) transporter
BW730_14575	COG0577	efflux transmembrane transporter activity
BW730_14580	COG0592	DNA-directed DNA polymerase activity
BW730_14585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BW730_14590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BW730_14625	COG0741	lytic transglycosylase activity
BW730_14625	COG0739	heme binding
BW730_14625	COG1196	nuclear chromosome segregation
BW730_14650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BW730_14655	COG3266	domain, Protein
BW730_14735	COG1053	succinate dehydrogenase
BW730_14775	COG1518	maintenance of DNA repeat elements
BW730_14820	COG2354	Protein conserved in bacteria
BW730_14825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BW730_14835	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BW730_14840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BW730_14865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BW730_14875	COG2076	Multidrug Resistance protein
BW730_14895	COG0640	Transcriptional regulator
BW730_14915	COG0861	Integral membrane protein TerC family
BW730_14925	COG2197	response regulator
BW730_14935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BW730_14950	COG2409	Drug exporters of the RND superfamily
BW730_14995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BW730_15000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BW730_15010	COG1349	DNA-binding transcription factor activity
BW730_15035	COG1028	Short-chain dehydrogenase reductase Sdr
BW730_15040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BW730_15050	COG3422	double-strand break repair
BW730_15075	COG1793	dna ligase
BW730_15110	COG0672	)-iron permease
BW730_15120	COG2837	iron assimilation
BW730_15145	COG1846	Transcriptional regulator
BW730_15155	COG0617	tRNA 3'-terminal CCA addition
BW730_15160	COG0668	transmembrane transport
BW730_15175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BW730_15185	COG2318	DinB family
BW730_15195	COG2318	DinB family
BW730_15225	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BW730_15240	COG4214	carbohydrate transport
BW730_15275	COG1349	DNA-binding transcription factor activity
BW730_15280	COG2814	Major facilitator Superfamily
BW730_15285	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BW730_15290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BW730_15290	COG0574	Belongs to the PEP-utilizing enzyme family
BW730_15320	COG0318	PFAM AMP-dependent synthetase and ligase
BW730_15320	COG0204	Acyl-transferase
BW730_15345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BW730_15350	COG2154	pterin-4-alpha-carbinolamine dehydratase
BW730_15360	COG1320	monovalent cation:proton antiporter activity
BW730_15370	COG1863	multisubunit Na H antiporter MnhE subunit
BW730_15390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BW730_15395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BW730_15400	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BW730_15405	COG0488	(ABC) transporter
BW730_15430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BW730_15440	COG0360	Binds together with S18 to 16S ribosomal RNA
BW730_15450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BW730_15455	COG0359	binds to the 23S rRNA
BW730_15460	COG0501	Belongs to the peptidase M48B family
BW730_15495	COG1760	l-serine dehydratase
BW730_15500	COG2814	Major facilitator Superfamily
BW730_15570	COG2184	nucleotidyltransferase activity
BW730_15575	COG0789	Transcriptional regulator
BW730_15605	COG1136	(ABC) transporter
BW730_15605	COG4591	ABC-type transport system involved in lipoprotein release permease component
BW730_15650	COG0574	Belongs to the PEP-utilizing enzyme family
BW730_15650	COG3848	Pyruvate phosphate dikinase
BW730_15655	COG1028	Short-chain dehydrogenase reductase Sdr
BW730_15695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BW730_15715	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BW730_15765	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BW730_15770	COG0028	Belongs to the TPP enzyme family
BW730_15780	COG1609	Transcriptional regulator
BW730_15810	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BW730_15815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BW730_15835	COG3212	peptidase
BW730_15860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BW730_15865	COG0737	Belongs to the 5'-nucleotidase family
BW730_15875	COG0022	dehydrogenase e1 component
BW730_15880	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW730_15890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BW730_15900	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BW730_15905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BW730_15950	COG1674	ftsk spoiiie
BW730_15955	COG1404	Belongs to the peptidase S8 family
BW730_15980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BW730_15985	COG0561	phosphatase activity
BW730_15995	COG1134	teichoic acid transport
BW730_16020	COG0438	transferase activity, transferring glycosyl groups
BW730_16025	COG1215	transferase activity, transferring glycosyl groups
BW730_16025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BW730_16030	COG0438	transferase activity, transferring glycosyl groups
BW730_16045	COG0137	argininosuccinate synthase activity
BW730_16050	COG0438	transferase activity, transferring glycosyl groups
BW730_16070	COG0438	transferase activity, transferring glycosyl groups
BW730_16130	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BW730_16140	COG0564	pseudouridine synthase activity
BW730_16155	COG1316	TRANSCRIPTIONal
BW730_16175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BW730_16190	COG0383	alpha-mannosidase activity
BW730_16195	COG3842	ATPase activity
BW730_16200	COG3833	ABC-type maltose transport systems, permease component
BW730_16205	COG1175	transmembrane transport
BW730_16225	COG1082	Xylose isomerase domain protein TIM barrel
BW730_16265	COG0584	glycerophosphoryl diester phosphodiesterase
BW730_16270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BW730_16285	COG0673	inositol 2-dehydrogenase activity
BW730_16295	COG1172	Belongs to the binding-protein-dependent transport system permease family
BW730_16300	COG1129	ABC transporter
BW730_16330	COG0800	Aldolase
BW730_16340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BW730_16375	COG1653	transport
BW730_16380	COG1609	Transcriptional regulator
BW730_16385	COG1597	lipid kinase activity
BW730_16420	COG3132	Protein of unknown function, DUF480
BW730_16445	COG1316	TRANSCRIPTIONal
BW730_16450	COG1086	Polysaccharide biosynthesis protein
BW730_16465	COG0297	glycogen (starch) synthase activity
BW730_16485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BW730_16500	COG0489	protein tyrosine kinase activity
BW730_16505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BW730_16530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BW730_16550	COG0714	Associated with various cellular activities
BW730_16585	COG0717	Belongs to the dCTP deaminase family
BW730_16590	COG2827	Endonuclease containing a URI domain
BW730_16595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BW730_16600	COG2205	protein histidine kinase activity
BW730_16605	COG0745	RESPONSE REGULATOR receiver
BW730_16615	COG1252	NADH dehydrogenase
BW730_16635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BW730_16660	COG1316	TRANSCRIPTIONal
BW730_16685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BW730_16690	COG0484	heat shock protein binding
BW730_16695	COG0789	Transcriptional regulator
BW730_16710	COG0673	inositol 2-dehydrogenase activity
BW730_16745	COG0058	SHG alpha-glucan phosphorylase activity
BW730_16750	COG0351	phosphomethylpyrimidine kinase
BW730_16750	COG0352	thiamine-phosphate diphosphorylase activity
BW730_16750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BW730_16755	COG0351	phosphomethylpyrimidine kinase
BW730_16760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BW730_16760	COG0352	thiamine-phosphate diphosphorylase activity
BW730_16760	COG0351	phosphomethylpyrimidine kinase
BW730_16770	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BW730_16775	COG1285	pathogenesis
BW730_16795	COG1175	transmembrane transport
BW730_16810	COG0156	8-amino-7-oxononanoate synthase activity
BW730_16815	COG1063	alcohol dehydrogenase
BW730_16825	COG0642	Histidine kinase
BW730_16835	COG2197	response regulator
BW730_16840	COG1136	(ABC) transporter
BW730_16840	COG4591	ABC-type transport system involved in lipoprotein release permease component
BW730_16850	COG0542	response to heat
BW730_16870	COG2133	pyrroloquinoline quinone binding
BW730_16885	COG0534	Mate efflux family protein
BW730_16900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BW730_16905	COG1704	LemA family
BW730_16915	COG2353	YceI-like domain
BW730_16930	COG0191	fructose-bisphosphate aldolase activity
BW730_16960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BW730_16980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BW730_16985	COG0346	lactoylglutathione lyase activity
BW730_16995	COG1070	Carbohydrate kinase
BW730_17005	COG0438	transferase activity, transferring glycosyl groups
BW730_17015	COG2610	gluconate transmembrane transporter activity
BW730_17020	COG3265	gluconokinase activity
BW730_17035	COG3458	cephalosporin-C deacetylase activity
BW730_17040	COG2186	Transcriptional regulator
BW730_17045	COG0747	negative chemotaxis
BW730_17055	COG0444	Belongs to the ABC transporter superfamily
BW730_17065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BW730_17070	COG1940	carbohydrate kinase activity
BW730_17075	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BW730_17100	COG0166	Belongs to the GPI family
BW730_17120	COG1175	transmembrane transport
BW730_17140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BW730_17160	COG0018	arginyl-trna synthetase
BW730_17165	COG1051	belongs to the nudix hydrolase family
BW730_17170	COG1940	carbohydrate kinase activity
BW730_17190	COG0205	6-phosphofructokinase activity
BW730_17200	COG0277	FAD linked oxidase domain protein
BW730_17250	COG0714	Associated with various cellular activities
BW730_17260	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BW730_17265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BW730_17270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BW730_17280	COG2326	polyphosphate kinase activity
BW730_17285	COG0546	phosphoglycolate phosphatase activity
BW730_17305	COG2011	ABC-type metal ion transport system permease component
BW730_17310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BW730_17345	COG1793	dna ligase
BW730_17360	COG1175	transmembrane transport
BW730_17365	COG0395	ABC-type sugar transport system, permease component
BW730_17370	COG1803	Methylglyoxal synthase
BW730_17390	COG2357	RelA SpoT domain protein
BW730_17415	COG1940	carbohydrate kinase activity
BW730_17415	COG1846	Transcriptional regulator
BW730_17425	COG0395	ABC-type sugar transport system, permease component
BW730_17430	COG1175	transmembrane transport
BW730_17440	COG0277	FAD linked oxidase domain protein
BW730_17445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BW730_17450	COG1088	dTDP-glucose 4,6-dehydratase activity
BW730_17460	COG0579	oxidoreductase
BW730_17465	COG2095	MarC family integral membrane protein
BW730_17495	COG0560	Phosphoserine phosphatase
BW730_17495	COG3830	Belongs to the UPF0237 family
BW730_17500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BW730_17505	COG2813	Specifically methylates the guanine in position
BW730_17515	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BW730_17520	COG2226	methyltransferase
BW730_17540	COG1136	(ABC) transporter
BW730_17550	COG2197	response regulator
BW730_17580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BW730_17585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BW730_17590	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BW730_17620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BW730_17640	COG0477	Major facilitator Superfamily
BW730_17645	COG1228	amidohydrolase
BW730_17690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BW730_17705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BW730_17750	COG1205	dead DEAH box helicase
BW730_17750	COG1111	helicase
BW730_17775	COG0667	Aldo Keto reductase
BW730_17790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BW730_17790	COG1754	DNA topoisomerase type I activity
BW730_17805	COG0730	response to heat
BW730_17810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BW730_17825	COG1774	PSP1 C-terminal conserved region
BW730_17880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BW730_17885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BW730_17890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BW730_17930	COG0302	gtp cyclohydrolase
BW730_17940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BW730_17960	COG0649	NAD binding
BW730_17970	COG0542	response to heat
BW730_18005	COG3842	ATPase activity