locus-tag	class	description
J7D54_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J7D54_00010	COG1937	Protein conserved in bacteria
J7D54_00015	COG0446	pyridine nucleotide-disulphide oxidoreductase
J7D54_00040	COG0577	efflux transmembrane transporter activity
J7D54_00040	COG1136	(ABC) transporter
J7D54_00050	COG0592	DNA-directed DNA polymerase activity
J7D54_00055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J7D54_00075	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
J7D54_00090	COG0739	heme binding
J7D54_00090	COG0741	lytic transglycosylase activity
J7D54_00090	COG1196	nuclear chromosome segregation
J7D54_00105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J7D54_00120	COG2814	Major facilitator Superfamily
J7D54_00125	COG1653	transport
J7D54_00130	COG0395	ABC-type sugar transport system, permease component
J7D54_00135	COG1175	transmembrane transport
J7D54_00145	COG1609	Transcriptional regulator
J7D54_00155	COG2084	Dehydrogenase
J7D54_00165	COG2376	Dihydroxyacetone kinase
J7D54_00170	COG0698	ribose 5-phosphate isomerase
J7D54_00190	COG0791	NLP P60 protein
J7D54_00200	COG2354	Protein conserved in bacteria
J7D54_00225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J7D54_00230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J7D54_00265	COG2076	Multidrug Resistance protein
J7D54_00295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J7D54_00300	COG1309	transcriptional regulator
J7D54_00305	COG2409	Drug exporters of the RND superfamily
J7D54_00335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J7D54_00340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J7D54_00345	COG1793	dna ligase
J7D54_00365	COG1132	(ABC) transporter
J7D54_00370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J7D54_00390	COG0477	Major facilitator Superfamily
J7D54_00400	COG0439	Biotin carboxylase
J7D54_00445	COG1129	ABC transporter
J7D54_00450	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_00475	COG2115	Belongs to the xylose isomerase family
J7D54_00490	COG5002	protein histidine kinase activity
J7D54_00495	COG0745	RESPONSE REGULATOR receiver
J7D54_00505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J7D54_00505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J7D54_00510	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_00535	COG0360	Binds together with S18 to 16S ribosomal RNA
J7D54_00540	COG0629	single-stranded DNA binding
J7D54_00545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J7D54_00550	COG0359	binds to the 23S rRNA
J7D54_00555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J7D54_00565	COG1609	Transcriptional regulator
J7D54_00575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J7D54_00580	COG1760	l-serine dehydratase
J7D54_00590	COG1846	Transcriptional regulator
J7D54_00595	COG4948	Mandelate Racemase Muconate Lactonizing
J7D54_00600	COG3254	rhamnose metabolic process
J7D54_00610	COG1129	ABC transporter
J7D54_00615	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_00620	COG0673	inositol 2-dehydrogenase activity
J7D54_00625	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_00630	COG0022	dehydrogenase e1 component
J7D54_00635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J7D54_00645	COG3618	amidohydrolase
J7D54_00650	COG1609	Transcriptional regulator
J7D54_00665	COG0662	Cupin 2, conserved barrel domain protein
J7D54_00690	COG1064	alcohol dehydrogenase
J7D54_00700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J7D54_00740	COG2258	MOSC domain
J7D54_00755	COG2318	DinB family
J7D54_00785	COG1051	belongs to the nudix hydrolase family
J7D54_00870	COG3655	Transcriptional regulator
J7D54_00890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7D54_00910	COG1595	DNA-templated transcription, initiation
J7D54_00930	COG2205	protein histidine kinase activity
J7D54_00945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J7D54_00950	COG1525	nuclease
J7D54_00950	COG4085	toxin activity
J7D54_00950	COG0737	Belongs to the 5'-nucleotidase family
J7D54_00960	COG0022	dehydrogenase e1 component
J7D54_00965	COG0508	dehydrogenase complex catalyzes the overall conversion of
J7D54_00975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J7D54_00985	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J7D54_00990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J7D54_01045	COG1674	ftsk spoiiie
J7D54_01050	COG1404	Belongs to the peptidase S8 family
J7D54_01065	COG2814	Major facilitator Superfamily
J7D54_01070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J7D54_01075	COG0561	phosphatase activity
J7D54_01115	COG0137	argininosuccinate synthase activity
J7D54_01145	COG2149	membrane
J7D54_01185	COG2154	pterin-4-alpha-carbinolamine dehydratase
J7D54_01195	COG3321	synthase
J7D54_01195	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_01195	COG0604	alcohol dehydrogenase
J7D54_01215	COG0564	pseudouridine synthase activity
J7D54_01230	COG1316	TRANSCRIPTIONal
J7D54_01245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J7D54_01265	COG2124	cytochrome p450
J7D54_01295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J7D54_01320	COG1201	RNA secondary structure unwinding
J7D54_01365	COG2132	Multicopper oxidase
J7D54_01365	COG2132	Multicopper oxidase
J7D54_01370	COG0745	RESPONSE REGULATOR receiver
J7D54_01390	COG0745	RESPONSE REGULATOR receiver
J7D54_01395	COG2205	protein histidine kinase activity
J7D54_01400	COG0778	Nitroreductase
J7D54_01410	COG2337	Toxic component of a toxin-antitoxin (TA) module
J7D54_01420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J7D54_01425	COG0584	glycerophosphoryl diester phosphodiesterase
J7D54_01430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J7D54_01445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J7D54_01455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J7D54_01465	COG0590	tRNA wobble adenosine to inosine editing
J7D54_01490	COG0433	COG0433 Predicted ATPase
J7D54_01495	COG1653	transport
J7D54_01505	COG3132	Protein of unknown function, DUF480
J7D54_01510	COG0673	inositol 2-dehydrogenase activity
J7D54_01520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J7D54_01545	COG0714	Associated with various cellular activities
J7D54_01565	COG0717	Belongs to the dCTP deaminase family
J7D54_01570	COG1132	(ABC) transporter
J7D54_01575	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J7D54_01585	COG2205	protein histidine kinase activity
J7D54_01590	COG0745	RESPONSE REGULATOR receiver
J7D54_01600	COG1252	NADH dehydrogenase
J7D54_01610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J7D54_01620	COG4585	Histidine kinase
J7D54_01625	COG2197	response regulator
J7D54_01640	COG0189	ligase activity
J7D54_01655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J7D54_01660	COG0484	heat shock protein binding
J7D54_01665	COG0789	Transcriptional regulator
J7D54_01695	COG0058	SHG alpha-glucan phosphorylase activity
J7D54_01710	COG0351	phosphomethylpyrimidine kinase
J7D54_01710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J7D54_01710	COG0352	thiamine-phosphate diphosphorylase activity
J7D54_01715	COG0351	phosphomethylpyrimidine kinase
J7D54_01720	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J7D54_01720	COG0352	thiamine-phosphate diphosphorylase activity
J7D54_01720	COG0351	phosphomethylpyrimidine kinase
J7D54_01730	COG0156	8-amino-7-oxononanoate synthase activity
J7D54_01735	COG1063	alcohol dehydrogenase
J7D54_01770	COG1175	transmembrane transport
J7D54_01775	COG0395	ABC-type sugar transport system, permease component
J7D54_01785	COG0542	response to heat
J7D54_01805	COG0259	pyridoxamine-phosphate oxidase activity
J7D54_01815	COG2133	pyrroloquinoline quinone binding
J7D54_01820	COG0534	Mate efflux family protein
J7D54_01870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J7D54_01875	COG1704	LemA family
J7D54_01880	COG2353	YceI-like domain
J7D54_01910	COG0191	fructose-bisphosphate aldolase activity
J7D54_01915	COG1404	Belongs to the peptidase S8 family
J7D54_01920	COG1404	Belongs to the peptidase S8 family
J7D54_01930	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_01945	COG1070	Carbohydrate kinase
J7D54_01950	COG1609	Transcriptional regulator
J7D54_01975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J7D54_02000	COG1595	DNA-templated transcription, initiation
J7D54_02020	COG1595	DNA-templated transcription, initiation
J7D54_02030	COG1595	DNA-templated transcription, initiation
J7D54_02075	COG1505	serine-type exopeptidase activity
J7D54_02105	COG1609	Transcriptional regulator
J7D54_02110	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_02130	COG0006	proline dipeptidase activity
J7D54_02145	COG0179	Fumarylacetoacetate (FAA) hydrolase
J7D54_02170	COG1414	Transcriptional regulator
J7D54_02205	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_02220	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_02230	COG1349	DNA-binding transcription factor activity
J7D54_02235	COG0508	dehydrogenase complex catalyzes the overall conversion of
J7D54_02240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J7D54_02245	COG0022	dehydrogenase e1 component
J7D54_02255	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_02280	COG1609	Transcriptional regulator
J7D54_02285	COG0395	ABC-type sugar transport system, permease component
J7D54_02290	COG1175	transmembrane transport
J7D54_02300	COG1472	Belongs to the glycosyl hydrolase 3 family
J7D54_02305	COG3458	cephalosporin-C deacetylase activity
J7D54_02340	COG1472	Belongs to the glycosyl hydrolase 3 family
J7D54_02350	COG3279	Response regulator of the LytR AlgR family
J7D54_02360	COG1216	Glycosyl transferase, family 2
J7D54_02370	COG1472	Belongs to the glycosyl hydrolase 3 family
J7D54_02420	COG0588	phosphoglycerate mutase activity
J7D54_02430	COG5002	protein histidine kinase activity
J7D54_02435	COG0745	RESPONSE REGULATOR receiver
J7D54_02445	COG1329	Transcriptional regulator
J7D54_02450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J7D54_02455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J7D54_02465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J7D54_02480	COG0215	cysteine-tRNA ligase activity
J7D54_02500	COG2197	response regulator
J7D54_02505	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J7D54_02510	COG2226	methyltransferase
J7D54_02535	COG0626	cystathionine gamma-synthase activity
J7D54_02540	COG3842	ATPase activity
J7D54_02595	COG0494	nUDIX hydrolase
J7D54_02605	COG0363	glucosamine-6-phosphate deaminase activity
J7D54_02610	COG1278	Cold shock
J7D54_02625	COG2252	PERMEase
J7D54_02640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J7D54_02655	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J7D54_02665	COG1321	iron dependent repressor
J7D54_02675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J7D54_02680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J7D54_02680	COG0493	'glutamate synthase
J7D54_02685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J7D54_02685	COG0674	pyruvate-flavodoxin oxidoreductase activity
J7D54_02685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J7D54_02685	COG1013	pyruvate-flavodoxin oxidoreductase activity
J7D54_02690	COG0167	dihydroorotate dehydrogenase activity
J7D54_02700	COG4974	Belongs to the 'phage' integrase family
J7D54_02825	COG1595	DNA-templated transcription, initiation
J7D54_02850	COG2132	Multicopper oxidase
J7D54_02870	COG1970	mechanosensitive ion channel activity
J7D54_02885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J7D54_02910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J7D54_02925	COG0395	ABC-type sugar transport system, permease component
J7D54_02955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J7D54_02960	COG2233	PERMEase
J7D54_02985	COG0084	hydrolase, TatD family'
J7D54_02990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J7D54_02995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J7D54_03010	COG2818	Glycosylase
J7D54_03070	COG0745	RESPONSE REGULATOR receiver
J7D54_03090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J7D54_03095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J7D54_03100	COG1136	(ABC) transporter
J7D54_03105	COG0577	efflux transmembrane transporter activity
J7D54_03120	COG1070	Carbohydrate kinase
J7D54_03125	COG4952	isomerase
J7D54_03140	COG3250	beta-galactosidase activity
J7D54_03145	COG0395	ABC-type sugar transport system, permease component
J7D54_03150	COG1175	transmembrane transport
J7D54_03165	COG1472	Belongs to the glycosyl hydrolase 3 family
J7D54_03170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J7D54_03175	COG0193	aminoacyl-tRNA hydrolase activity
J7D54_03195	COG0148	phosphopyruvate hydratase activity
J7D54_03220	COG2268	Band 7 protein
J7D54_03235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J7D54_03250	COG2321	neutral zinc metallopeptidase
J7D54_03295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J7D54_03310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J7D54_03320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J7D54_03330	COG1331	Highly conserved protein containing a thioredoxin domain
J7D54_03350	COG1175	transmembrane transport
J7D54_03355	COG0395	ABC-type sugar transport system, permease component
J7D54_03390	COG0577	efflux transmembrane transporter activity
J7D54_03390	COG1136	(ABC) transporter
J7D54_03400	COG0577	efflux transmembrane transporter activity
J7D54_03405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J7D54_03420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J7D54_03430	COG1722	exodeoxyribonuclease VII activity
J7D54_03435	COG1570	exodeoxyribonuclease VII activity
J7D54_03445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J7D54_03455	COG1322	Protein conserved in bacteria
J7D54_03460	COG1362	aminopeptidase activity
J7D54_03465	COG4604	ABC transporter, ATP-binding protein
J7D54_03470	COG4605	iron ion homeostasis
J7D54_03475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J7D54_03480	COG4607	ABC-type enterochelin transport system periplasmic component
J7D54_03485	COG0012	GTP binding
J7D54_03575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J7D54_03595	COG1278	Cold shock
J7D54_03600	COG1024	Enoyl-CoA hydratase
J7D54_03620	COG0745	RESPONSE REGULATOR receiver
J7D54_03625	COG2205	protein histidine kinase activity
J7D54_03635	COG0702	epimerase
J7D54_03645	COG3361	conserved protein (COG2071)
J7D54_03670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J7D54_03685	COG1045	serine acetyltransferase
J7D54_03700	COG1335	isochorismatase
J7D54_03720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J7D54_03735	COG0616	signal peptide processing
J7D54_03740	COG2720	vancomycin resistance protein
J7D54_03755	COG1132	(ABC) transporter
J7D54_03770	COG2171	N-acyltransferase activity
J7D54_03775	COG1414	Transcriptional regulator
J7D54_03790	COG0477	Major facilitator Superfamily
J7D54_03795	COG1054	Belongs to the UPF0176 family
J7D54_03800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J7D54_03805	COG1611	Belongs to the LOG family
J7D54_03820	COG0297	glycogen (starch) synthase activity
J7D54_03825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J7D54_03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J7D54_03850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J7D54_03855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J7D54_03875	COG2239	Acts as a magnesium transporter
J7D54_03880	COG2301	Belongs to the HpcH HpaI aldolase family
J7D54_03900	COG0006	proline dipeptidase activity
J7D54_03905	COG1072	(Pantothenic acid kinase))
J7D54_03910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J7D54_03915	COG0736	holo-[acyl-carrier-protein] synthase activity
J7D54_03930	COG2847	Copper chaperone PCu(A)C
J7D54_03935	COG0438	transferase activity, transferring glycosyl groups
J7D54_03935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J7D54_03940	COG0513	Belongs to the DEAD box helicase family
J7D54_03945	COG0802	atpase or kinase
J7D54_03960	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J7D54_03965	COG0747	negative chemotaxis
J7D54_03975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J7D54_03990	COG2816	NAD+ diphosphatase activity
J7D54_04005	COG2826	transposase and inactivated derivatives, IS30 family
J7D54_04020	COG1175	transmembrane transport
J7D54_04025	COG0395	ABC-type sugar transport system, permease component
J7D54_04055	COG0745	RESPONSE REGULATOR receiver
J7D54_04065	COG5002	protein histidine kinase activity
J7D54_04070	COG2826	transposase and inactivated derivatives, IS30 family
J7D54_04075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J7D54_04080	COG0459	protein refolding
J7D54_04085	COG0494	nUDIX hydrolase
J7D54_04100	COG0549	Belongs to the carbamate kinase family
J7D54_04105	COG0666	response to abiotic stimulus
J7D54_04115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J7D54_04120	COG1304	FMN binding
J7D54_04125	COG1953	Uracil, thiamine, allantoin
J7D54_04130	COG0590	tRNA wobble adenosine to inosine editing
J7D54_04140	COG0516	GMP reductase activity
J7D54_04145	COG0287	Prephenate dehydrogenase
J7D54_04145	COG1605	Chorismate mutase
J7D54_04165	COG1131	(ABC) transporter
J7D54_04190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J7D54_04200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J7D54_04200	COG0519	Catalyzes the synthesis of GMP from XMP
J7D54_04225	COG2197	response regulator
J7D54_04255	COG2894	cell division
J7D54_04305	COG0045	succinate-CoA ligase (ADP-forming) activity
J7D54_04330	COG0138	bifunctional purine biosynthesis protein purh
J7D54_04335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J7D54_04360	COG0039	L-malate dehydrogenase activity
J7D54_04365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J7D54_04380	COG1253	flavin adenine dinucleotide binding
J7D54_04390	COG1744	ABC transporter substrate-binding protein PnrA-like
J7D54_04395	COG3845	ABC transporter
J7D54_04400	COG4603	Belongs to the binding-protein-dependent transport system permease family
J7D54_04405	COG1079	Belongs to the binding-protein-dependent transport system permease family
J7D54_04420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J7D54_04435	COG2197	response regulator
J7D54_04455	COG0328	RNA-DNA hybrid ribonuclease activity
J7D54_04460	COG0659	secondary active sulfate transmembrane transporter activity
J7D54_04465	COG3012	SEC-C Motif Domain Protein
J7D54_04495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J7D54_04505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J7D54_04515	COG1053	succinate dehydrogenase
J7D54_04545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J7D54_04560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J7D54_04570	COG4770	biotin carboxylase activity
J7D54_04585	COG0424	maF-like protein
J7D54_04595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J7D54_04625	COG1316	TRANSCRIPTIONal
J7D54_04630	COG1316	TRANSCRIPTIONal
J7D54_04695	COG2835	tetraacyldisaccharide 4'-kinase activity
J7D54_04705	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J7D54_04710	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J7D54_04725	COG0515	serine threonine protein kinase
J7D54_04725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J7D54_04765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J7D54_04775	COG3033	Beta-eliminating lyase
J7D54_04780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J7D54_04785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J7D54_04790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J7D54_04795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J7D54_04810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J7D54_04835	COG0765	amino acid transport
J7D54_04840	COG0765	amino acid transport
J7D54_04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7D54_04850	COG1126	abc transporter atp-binding protein
J7D54_04860	COG1215	transferase activity, transferring glycosyl groups
J7D54_04865	COG1366	Belongs to the anti-sigma-factor antagonist family
J7D54_04875	COG1739	Uncharacterized protein family UPF0029
J7D54_04910	COG2226	methyltransferase
J7D54_04930	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
J7D54_04945	COG0708	Exodeoxyribonuclease III
J7D54_04955	COG0515	serine threonine protein kinase
J7D54_04980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J7D54_05000	COG2860	membrane
J7D54_05020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J7D54_05055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J7D54_05075	COG1595	DNA-templated transcription, initiation
J7D54_05080	COG0277	FAD linked oxidase domain protein
J7D54_05090	COG1022	Amp-dependent synthetase and ligase
J7D54_05100	COG3507	Belongs to the glycosyl hydrolase 43 family
J7D54_05105	COG3534	alpha-L-arabinofuranosidase
J7D54_05125	COG1175	transmembrane transport
J7D54_05130	COG0395	ABC-type sugar transport system, permease component
J7D54_05150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J7D54_05155	COG1201	RNA secondary structure unwinding
J7D54_05160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J7D54_05195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J7D54_05200	COG0540	Belongs to the ATCase OTCase family
J7D54_05205	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J7D54_05220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J7D54_05255	COG4585	Histidine kinase
J7D54_05260	COG2197	response regulator
J7D54_05295	COG1846	Transcriptional regulator
J7D54_05300	COG2409	Drug exporters of the RND superfamily
J7D54_05315	COG2801	Transposase and inactivated derivatives
J7D54_05315	COG3415	Transposase
J7D54_05335	COG0544	peptidyl-prolyl cis-trans isomerase activity
J7D54_05340	COG0740	serine-type endopeptidase activity
J7D54_05345	COG0740	serine-type endopeptidase activity
J7D54_05350	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J7D54_05355	COG4946	Tricorn protease homolog
J7D54_05355	COG0793	Belongs to the peptidase S41A family
J7D54_05360	COG0525	valine-tRNA ligase activity
J7D54_05370	COG0285	dihydrofolate synthase activity
J7D54_05380	COG0105	UTP biosynthetic process
J7D54_05395	COG0596	Alpha beta hydrolase
J7D54_05395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J7D54_05400	COG4868	Belongs to the UPF0371 family
J7D54_05410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J7D54_05440	COG1530	ribonuclease E activity
J7D54_05450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J7D54_05455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J7D54_05465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J7D54_05470	COG0742	ribosomal rna small subunit methyltransferase
J7D54_05475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J7D54_05485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J7D54_05490	COG0571	ribonuclease III activity
J7D54_05495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J7D54_05515	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J7D54_05520	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J7D54_05525	COG0514	ATP-dependent DNA helicase (RecQ)
J7D54_05560	COG1017	nitric oxide dioxygenase activity
J7D54_05560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J7D54_05565	COG0228	four-way junction DNA binding
J7D54_05570	COG1837	Belongs to the UPF0109 family
J7D54_05575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J7D54_05580	COG0336	Belongs to the RNA methyltransferase TrmD family
J7D54_05590	COG1053	succinate dehydrogenase
J7D54_05595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J7D54_05600	COG0335	large ribosomal subunit rRNA binding
J7D54_05610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J7D54_05620	COG0792	nuclease activity
J7D54_05645	COG3845	ABC transporter
J7D54_05685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J7D54_05700	COG0640	Transcriptional regulator
J7D54_05715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J7D54_05720	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_05730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J7D54_05745	COG0667	Aldo Keto reductase
J7D54_05750	COG1968	undecaprenyl-diphosphatase activity
J7D54_05770	COG0215	cysteine-tRNA ligase activity
J7D54_05775	COG0140	phosphoribosyl-ATP diphosphatase activity
J7D54_05780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J7D54_05800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J7D54_05805	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J7D54_05810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J7D54_05820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J7D54_05825	COG0072	phenylalanine-tRNA ligase activity
J7D54_05825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J7D54_05845	COG2124	cytochrome p450
J7D54_05855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J7D54_05860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J7D54_05865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J7D54_05870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J7D54_05880	COG0165	Argininosuccinate lyase
J7D54_05890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J7D54_05940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J7D54_05945	COG0497	DNA recombination
J7D54_05955	COG0504	CTP synthase activity
J7D54_05960	COG0494	nUDIX hydrolase
J7D54_05985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J7D54_05990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J7D54_06015	COG1643	Atp-dependent helicase
J7D54_06020	COG1946	Acyl-CoA thioesterase
J7D54_06030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J7D54_06040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J7D54_06040	COG0519	Catalyzes the synthesis of GMP from XMP
J7D54_06045	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
J7D54_06060	COG1074	ATP-dependent DNA helicase activity
J7D54_06065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J7D54_06090	COG3480	Lon protease (S16) C-terminal proteolytic domain
J7D54_06100	COG1615	UPF0182 protein
J7D54_06115	COG0667	Aldo Keto reductase
J7D54_06200	COG0433	COG0433 Predicted ATPase
J7D54_06250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J7D54_06280	COG1192	Involved in chromosome partitioning
J7D54_06290	COG0358	DNA primase activity
J7D54_06340	COG2197	response regulator
J7D54_06390	COG1609	Transcriptional regulator
J7D54_06405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J7D54_06410	COG0444	Belongs to the ABC transporter superfamily
J7D54_06420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J7D54_06425	COG0483	inositol monophosphate 1-phosphatase activity
J7D54_06430	COG1162	GTPase activity
J7D54_06435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J7D54_06445	COG2135	peptidase activity
J7D54_06455	COG0488	(ABC) transporter
J7D54_06460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J7D54_06465	COG0366	Alpha amylase catalytic
J7D54_06470	COG2190	(PTS) system
J7D54_06470	COG2211	Major facilitator Superfamily
J7D54_06475	COG2226	methyltransferase
J7D54_06490	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_06500	COG1119	ATPase activity
J7D54_06530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J7D54_06545	COG0242	peptide deformylase activity
J7D54_06550	COG4974	Belongs to the 'phage' integrase family
J7D54_06555	COG0318	PFAM AMP-dependent synthetase and ligase
J7D54_06565	COG0052	Belongs to the universal ribosomal protein uS2 family
J7D54_06570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J7D54_06575	COG0528	UMP kinase activity
J7D54_06580	COG0233	cytoplasmic translational termination
J7D54_06590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J7D54_06595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J7D54_06605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J7D54_06610	COG0750	zinc metalloprotease
J7D54_06615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J7D54_06620	COG0456	acetyltransferase
J7D54_06620	COG0454	-acetyltransferase
J7D54_06625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J7D54_06630	COG0442	prolyl-tRNA aminoacylation
J7D54_06640	COG0779	Required for maturation of 30S ribosomal subunits
J7D54_06650	COG3583	domain protein
J7D54_06675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J7D54_06680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J7D54_06685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J7D54_06705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J7D54_06710	COG1012	belongs to the aldehyde dehydrogenase family
J7D54_06715	COG1185	polyribonucleotide nucleotidyltransferase activity
J7D54_06720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J7D54_06730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J7D54_06735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J7D54_06740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J7D54_06745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J7D54_06750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J7D54_06760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J7D54_06770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J7D54_06785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J7D54_06785	COG3253	May function as heme-dependent peroxidase
J7D54_06790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J7D54_06795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J7D54_06800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J7D54_06810	COG0181	hydroxymethylbilane synthase activity
J7D54_06820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J7D54_06825	COG0181	hydroxymethylbilane synthase activity
J7D54_06835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J7D54_06845	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_06870	COG3409	Peptidoglycan-binding domain 1 protein
J7D54_06870	COG0860	N-Acetylmuramoyl-L-alanine amidase
J7D54_06890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J7D54_06895	COG0495	leucyl-tRNA aminoacylation
J7D54_06920	COG0268	Binds directly to 16S ribosomal RNA
J7D54_06925	COG0481	GTPase activity
J7D54_06930	COG1643	Atp-dependent helicase
J7D54_06945	COG1116	anion transmembrane transporter activity
J7D54_06950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7D54_06970	COG1131	(ABC) transporter
J7D54_06995	COG1420	regulation of RNA biosynthetic process
J7D54_07000	COG0484	heat shock protein binding
J7D54_07010	COG0343	queuine tRNA-ribosyltransferase activity
J7D54_07030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J7D54_07045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J7D54_07055	COG1175	transmembrane transport
J7D54_07060	COG0395	ABC-type sugar transport system, permease component
J7D54_07065	COG1131	(ABC) transporter
J7D54_07070	COG3559	Exporter of polyketide antibiotics
J7D54_07075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J7D54_07090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J7D54_07095	COG1381	Involved in DNA repair and RecF pathway recombination
J7D54_07100	COG0561	phosphatase activity
J7D54_07110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J7D54_07115	COG1121	(ABC) transporter
J7D54_07120	COG0803	Belongs to the bacterial solute-binding protein 9 family
J7D54_07140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J7D54_07150	COG0358	DNA primase activity
J7D54_07160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J7D54_07175	COG0070	glutamate synthase
J7D54_07175	COG0069	glutamate synthase activity
J7D54_07175	COG0067	glutamate synthase
J7D54_07185	COG2985	domain, Protein
J7D54_07185	COG0569	domain protein
J7D54_07190	COG0587	DNA-directed DNA polymerase activity
J7D54_07200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J7D54_07205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J7D54_07210	COG0131	Imidazoleglycerol-phosphate dehydratase
J7D54_07220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J7D54_07245	COG0217	transcriptional regulatory protein
J7D54_07250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J7D54_07255	COG0632	four-way junction helicase activity
J7D54_07260	COG2255	four-way junction helicase activity
J7D54_07265	COG1862	Preprotein translocase
J7D54_07270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J7D54_07275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J7D54_07280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J7D54_07290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J7D54_07295	COG1196	nuclear chromosome segregation
J7D54_07300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J7D54_07305	COG0124	histidyl-tRNA synthetase
J7D54_07310	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J7D54_07315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J7D54_07335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J7D54_07340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J7D54_07350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J7D54_07355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J7D54_07360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J7D54_07365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J7D54_07385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J7D54_07390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J7D54_07395	COG0505	Belongs to the CarA family
J7D54_07400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J7D54_07405	COG0167	dihydroorotate dehydrogenase activity
J7D54_07410	COG0284	orotidine-5'-phosphate decarboxylase activity
J7D54_07420	COG0194	GDP metabolic process
J7D54_07425	COG1758	RNA polymerase activity
J7D54_07430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J7D54_07435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J7D54_07440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J7D54_07450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J7D54_07460	COG0646	methionine synthase
J7D54_07460	COG1410	methionine synthase
J7D54_07465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J7D54_07480	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
J7D54_07485	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
J7D54_07495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J7D54_07500	COG1160	GTP binding
J7D54_07505	COG0659	secondary active sulfate transmembrane transporter activity
J7D54_07600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J7D54_07605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J7D54_07605	COG2813	Specifically methylates the guanine in position
J7D54_07610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J7D54_07620	COG0463	Glycosyl transferase, family 2
J7D54_07625	COG3030	protein affecting phage T7 exclusion by the F plasmid
J7D54_07640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J7D54_07645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J7D54_07655	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_07665	COG0537	adenosine 5'-monophosphoramidase activity
J7D54_07685	COG0009	L-threonylcarbamoyladenylate synthase
J7D54_07690	COG0656	L-ascorbic acid biosynthetic process
J7D54_07710	COG1295	ribonuclease BN
J7D54_07730	COG1716	ATPase activity
J7D54_07755	COG0438	transferase activity, transferring glycosyl groups
J7D54_07760	COG1560	Kdo2-lipid A biosynthetic process
J7D54_07770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J7D54_07775	COG5006	permease, DMT superfamily
J7D54_07785	COG2860	membrane
J7D54_07845	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J7D54_07855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J7D54_07860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J7D54_07870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J7D54_07875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J7D54_07880	COG0531	amino acid
J7D54_07885	COG0569	domain protein
J7D54_07905	COG0756	dUTP diphosphatase activity
J7D54_07935	COG1435	thymidine kinase activity
J7D54_07940	COG0438	transferase activity, transferring glycosyl groups
J7D54_07960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J7D54_07975	COG1620	l-lactate permease
J7D54_07980	COG0247	lactate metabolic process
J7D54_07985	COG1139	Iron-sulfur cluster binding protein
J7D54_07990	COG1556	Lactate utilization protein
J7D54_07995	COG0187	DNA topoisomerase II activity
J7D54_08020	COG1793	dna ligase
J7D54_08020	COG3285	dna ligase
J7D54_08045	COG0613	PHP domain protein
J7D54_08055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J7D54_08080	COG0653	protein targeting
J7D54_08085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J7D54_08090	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J7D54_08095	COG5401	PFAM Sporulation and spore germination
J7D54_08100	COG5002	protein histidine kinase activity
J7D54_08105	COG0745	RESPONSE REGULATOR receiver
J7D54_08125	COG1678	Uncharacterized ACR, COG1678
J7D54_08140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J7D54_08145	COG0741	lytic transglycosylase activity
J7D54_08145	COG1196	nuclear chromosome segregation
J7D54_08145	COG0739	heme binding
J7D54_08155	COG2884	Cell division ATP-binding protein ftsE
J7D54_08160	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J7D54_08180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J7D54_08185	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J7D54_08200	COG0205	6-phosphofructokinase activity
J7D54_08210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J7D54_08215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J7D54_08215	COG1796	DNA polymerase
J7D54_08220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J7D54_08220	COG1648	precorrin-2 dehydrogenase activity
J7D54_08225	COG1115	amino acid carrier protein
J7D54_08245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J7D54_08250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J7D54_08280	COG1752	Esterase of the alpha-beta hydrolase superfamily
J7D54_08290	COG2304	oxidoreductase activity
J7D54_08295	COG2304	oxidoreductase activity
J7D54_08305	COG0714	Associated with various cellular activities
J7D54_08330	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
J7D54_08375	COG0133	tryptophan synthase activity
J7D54_08380	COG0134	indole-3-glycerol-phosphate synthase activity
J7D54_08395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J7D54_08400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J7D54_08410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J7D54_08415	COG0154	amidase activity
J7D54_08420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J7D54_08435	COG0482	sulfurtransferase activity
J7D54_08440	COG0583	DNA-binding transcription factor activity
J7D54_08445	COG2855	membrane
J7D54_08460	COG0366	Alpha amylase catalytic
J7D54_08480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J7D54_08540	COG0596	Alpha beta hydrolase
J7D54_08545	COG0730	response to heat
J7D54_08550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J7D54_08555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J7D54_08570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J7D54_08575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J7D54_08580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J7D54_08585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J7D54_08590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J7D54_08595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J7D54_08605	COG0356	it plays a direct role in the translocation of protons across the membrane
J7D54_08625	COG2890	protein-(glutamine-N5) methyltransferase activity
J7D54_08630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J7D54_08635	COG0254	rRNA binding
J7D54_08645	COG0083	homoserine kinase activity
J7D54_08650	COG0460	homoserine dehydrogenase
J7D54_08655	COG0019	diaminopimelate decarboxylase activity
J7D54_08675	COG0567	Dehydrogenase, E1 component
J7D54_08675	COG0508	dehydrogenase complex catalyzes the overall conversion of
J7D54_08675	COG0567	Dehydrogenase, E1 component
J7D54_08675	COG0508	dehydrogenase complex catalyzes the overall conversion of
J7D54_08685	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J7D54_08710	COG1595	DNA-templated transcription, initiation
J7D54_08715	COG0066	3-isopropylmalate dehydratase activity
J7D54_08720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J7D54_08725	COG1414	Transcriptional regulator
J7D54_08730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J7D54_08755	COG0179	Fumarylacetoacetate (FAA) hydrolase
J7D54_08760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J7D54_08765	COG0473	3-isopropylmalate dehydrogenase activity
J7D54_08770	COG2239	Acts as a magnesium transporter
J7D54_08780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J7D54_08785	COG0440	acetolactate synthase activity
J7D54_08800	COG0537	adenosine 5'-monophosphoramidase activity
J7D54_08805	COG0107	imidazoleglycerol-phosphate synthase activity
J7D54_08810	COG4581	dead DEAH box helicase
J7D54_08815	COG1597	lipid kinase activity
J7D54_08820	COG0805	protein transport
J7D54_08825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J7D54_08840	COG2378	regulation of single-species biofilm formation
J7D54_08845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J7D54_08850	COG0545	Peptidyl-prolyl cis-trans isomerase
J7D54_08865	COG0598	Magnesium transport protein CorA
J7D54_08870	COG0129	dihydroxy-acid dehydratase activity
J7D54_08875	COG5426	von Willebrand factor, type A
J7D54_08900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J7D54_08905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J7D54_08925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J7D54_08930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J7D54_08935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J7D54_08945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J7D54_08950	COG2017	converts alpha-aldose to the beta-anomer
J7D54_08955	COG1418	mRNA catabolic process
J7D54_08960	COG2137	regulation of response to DNA damage stimulus
J7D54_08980	COG1396	sequence-specific DNA binding
J7D54_08985	COG1058	Belongs to the CinA family
J7D54_08985	COG1546	Belongs to the CinA family
J7D54_08995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J7D54_09000	COG1674	ftsk spoiiie
J7D54_09010	COG1181	Belongs to the D-alanine--D-alanine ligase family
J7D54_09045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J7D54_09050	COG0396	ATPase activity
J7D54_09060	COG0719	Fe-S assembly protein
J7D54_09090	COG0339	signal peptide processing
J7D54_09095	COG2318	DinB family
J7D54_09105	COG4946	Tricorn protease homolog
J7D54_09105	COG1506	peptidase
J7D54_09105	COG0823	Involved in the tonB-independent uptake of proteins
J7D54_09110	COG0109	protoheme IX farnesyltransferase activity
J7D54_09125	COG0363	glucosamine-6-phosphate deaminase activity
J7D54_09135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J7D54_09140	COG0149	triose-phosphate isomerase activity
J7D54_09145	COG0126	phosphoglycerate kinase activity
J7D54_09150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J7D54_09155	COG1481	regulation of sporulation
J7D54_09165	COG1660	Displays ATPase and GTPase activities
J7D54_09175	COG1122	ATPase activity
J7D54_09180	COG1268	BioY protein
J7D54_09185	COG0322	excinuclease ABC activity
J7D54_09195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J7D54_09205	COG0556	nucleotide-excision repair
J7D54_09210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J7D54_09215	COG0509	glycine decarboxylation via glycine cleavage system
J7D54_09220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J7D54_09220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J7D54_09225	COG0237	dephospho-CoA kinase activity
J7D54_09235	COG0539	negative regulation of cytoplasmic translation
J7D54_09250	COG2050	protein possibly involved in aromatic compounds catabolism
J7D54_09265	COG0469	pyruvate kinase activity
J7D54_09275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J7D54_09295	COG1799	cell septum assembly
J7D54_09305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J7D54_09310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J7D54_09315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J7D54_09320	COG0772	Belongs to the SEDS family
J7D54_09325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J7D54_09330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J7D54_09335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J7D54_09355	COG0275	rRNA processing
J7D54_09360	COG2001	Belongs to the MraZ family
J7D54_09365	COG0714	Associated with various cellular activities
J7D54_09390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J7D54_09395	COG0587	DNA-directed DNA polymerase activity
J7D54_09415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J7D54_09415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J7D54_09420	COG3973	AAA domain
J7D54_09430	COG0142	geranyltranstransferase activity
J7D54_09440	COG0352	thiamine-phosphate diphosphorylase activity
J7D54_09445	COG0515	serine threonine protein kinase
J7D54_09445	COG2815	serine threonine protein kinase
J7D54_09455	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J7D54_09465	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J7D54_09470	COG2197	response regulator
J7D54_09480	COG0204	Acyl-transferase
J7D54_09500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J7D54_09505	COG0088	Forms part of the polypeptide exit tunnel
J7D54_09510	COG3214	Protein conserved in bacteria
J7D54_09520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J7D54_09535	COG1845	cytochrome c oxidase, subunit III
J7D54_09540	COG2010	Cytochrome c
J7D54_09545	COG0723	plastoquinol--plastocyanin reductase activity
J7D54_09550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J7D54_09565	COG4585	Histidine kinase
J7D54_09570	COG2197	response regulator
J7D54_09575	COG4152	abc transporter atp-binding protein
J7D54_09590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J7D54_09595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J7D54_09635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J7D54_09645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J7D54_09650	COG0508	dehydrogenase complex catalyzes the overall conversion of
J7D54_09660	COG0321	lipoyl(octanoyl) transferase activity
J7D54_09665	COG1215	transferase activity, transferring glycosyl groups
J7D54_09670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J7D54_09680	COG0488	(ABC) transporter
J7D54_09695	COG4044	May play a role in the intracellular transport of hydrophobic ligands
J7D54_09725	COG1823	symporter activity
J7D54_09730	COG0174	glutamine synthetase
J7D54_09735	COG2409	Drug exporters of the RND superfamily
J7D54_09740	COG0534	Mate efflux family protein
J7D54_09745	COG0604	alcohol dehydrogenase
J7D54_09765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7D54_09770	COG2910	NAD(P)H-binding
J7D54_09775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J7D54_09785	COG0656	L-ascorbic acid biosynthetic process
J7D54_09790	COG0174	glutamine synthetase
J7D54_09830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J7D54_09835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J7D54_09840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J7D54_09850	COG3655	Transcriptional regulator
J7D54_09870	COG3304	Inner membrane component domain
J7D54_09875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J7D54_09880	COG0101	tRNA pseudouridine synthase activity
J7D54_09895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J7D54_09895	COG2755	lipolytic protein G-D-S-L family
J7D54_09905	COG0438	transferase activity, transferring glycosyl groups
J7D54_09910	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J7D54_09915	COG4120	Belongs to the binding-protein-dependent transport system permease family
J7D54_09930	COG0203	ribosomal protein L17
J7D54_09935	COG0202	RNA polymerase activity
J7D54_09940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J7D54_09945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J7D54_09950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J7D54_09955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J7D54_09960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J7D54_09985	COG0563	adenylate kinase activity
J7D54_10005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J7D54_10010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J7D54_10015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J7D54_10020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J7D54_10025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J7D54_10030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J7D54_10035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J7D54_10040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J7D54_10055	COG1950	PFAM Membrane protein of
J7D54_10065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J7D54_10070	COG0255	Belongs to the universal ribosomal protein uL29 family
J7D54_10075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J7D54_10080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J7D54_10085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J7D54_10090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J7D54_10095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J7D54_10100	COG0089	rRNA binding
J7D54_10105	COG0088	Forms part of the polypeptide exit tunnel
J7D54_10110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J7D54_10115	COG0051	transcription antitermination factor activity, RNA binding
J7D54_10155	COG0435	Glutathione S-transferase
J7D54_10170	COG0281	malic enzyme
J7D54_10175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J7D54_10185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J7D54_10205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J7D54_10210	COG2153	protein acetylation
J7D54_10215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J7D54_10220	COG0049	tRNA binding
J7D54_10225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J7D54_10230	COG4213	ABC transporter substrate-binding protein
J7D54_10240	COG4214	carbohydrate transport
J7D54_10245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J7D54_10250	COG0085	RNA polymerase activity
J7D54_10255	COG0222	ribosome binding
J7D54_10260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J7D54_10270	COG0765	amino acid transport
J7D54_10275	COG1126	abc transporter atp-binding protein
J7D54_10295	COG0081	regulation of translation
J7D54_10300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J7D54_10305	COG0250	Participates in transcription elongation, termination and antitermination
J7D54_10320	COG2197	response regulator
J7D54_10325	COG4585	Histidine kinase
J7D54_10335	COG1132	(ABC) transporter
J7D54_10340	COG1132	(ABC) transporter
J7D54_10345	COG0641	radical SAM
J7D54_10350	COG1473	amidohydrolase
J7D54_10360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J7D54_10370	COG2030	dehydratase
J7D54_10375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J7D54_10390	COG0813	purine-nucleoside phosphorylase activity
J7D54_10400	COG1666	GTP binding
J7D54_10405	COG0708	Exodeoxyribonuclease III
J7D54_10415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7D54_10425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7D54_10430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J7D54_10440	COG0674	pyruvate-flavodoxin oxidoreductase activity
J7D54_10440	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J7D54_10445	COG1013	pyruvate-flavodoxin oxidoreductase activity
J7D54_10455	COG3590	peptidase
J7D54_10465	COG1175	transmembrane transport
J7D54_10470	COG0395	ABC-type sugar transport system, permease component
J7D54_10475	COG2723	6-phospho-beta-galactosidase activity
J7D54_10490	COG0142	geranyltranstransferase activity
J7D54_10495	COG1007	ATP synthesis coupled electron transport
J7D54_10520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7D54_10525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J7D54_10530	COG1034	ATP synthesis coupled electron transport
J7D54_10535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J7D54_10545	COG0649	NAD binding
J7D54_10550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7D54_10555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7D54_10565	COG0644	oxidoreductase
J7D54_10570	COG1169	isochorismate synthase
J7D54_10580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J7D54_10585	COG2226	methyltransferase
J7D54_10595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J7D54_10600	COG4948	Mandelate Racemase Muconate Lactonizing
J7D54_10625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J7D54_10630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J7D54_10635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J7D54_10645	COG0752	glycyl-tRNA synthetase alpha subunit
J7D54_10645	COG0751	glycine-tRNA ligase activity
J7D54_10660	COG5607	PFAM CHAD domain containing protein
J7D54_10660	COG3025	triphosphatase activity
J7D54_10670	COG0459	protein refolding
J7D54_10705	COG2838	Isocitrate dehydrogenase
J7D54_10715	COG0693	protein deglycase activity
J7D54_10720	COG2353	YceI-like domain
J7D54_10735	COG0577	efflux transmembrane transporter activity
J7D54_10735	COG1136	(ABC) transporter
J7D54_10740	COG0577	efflux transmembrane transporter activity
J7D54_10740	COG1136	(ABC) transporter
J7D54_10750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J7D54_10775	COG0521	Mo-molybdopterin cofactor biosynthetic process
J7D54_10780	COG0315	cyclic pyranopterin monophosphate synthase activity
J7D54_10825	COG1140	nitrate reductase beta subunit
J7D54_10835	COG0746	molybdenum cofactor guanylyltransferase activity
J7D54_10845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J7D54_10855	COG3833	ABC-type maltose transport systems, permease component
J7D54_10870	COG1609	Transcriptional regulator
J7D54_10875	COG0366	Alpha amylase catalytic
J7D54_10880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J7D54_10900	COG2070	2-Nitropropane dioxygenase
J7D54_10910	COG0494	nUDIX hydrolase
J7D54_10920	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J7D54_10930	COG1333	cytochrome c biogenesis protein
J7D54_10935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J7D54_10960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J7D54_10965	COG1404	Belongs to the peptidase S8 family
J7D54_10975	COG3622	Belongs to the hyi family
J7D54_10980	COG2084	Dehydrogenase
J7D54_10985	COG1929	Belongs to the glycerate kinase type-1 family
J7D54_10990	COG0228	four-way junction DNA binding
J7D54_10995	COG0047	phosphoribosylformylglycinamidine synthase activity
J7D54_11000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J7D54_11010	COG0436	Aminotransferase
J7D54_11020	COG2094	Belongs to the DNA glycosylase MPG family
J7D54_11040	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J7D54_11065	COG0175	sulfate reduction
J7D54_11070	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J7D54_11080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J7D54_11105	COG1609	Transcriptional regulator
J7D54_11115	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_11120	COG0183	Belongs to the thiolase family
J7D54_11140	COG0151	Belongs to the GarS family
J7D54_11150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J7D54_11160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J7D54_11165	COG2376	Dihydroxyacetone kinase
J7D54_11170	COG1461	Dihydroxyacetone kinase
J7D54_11190	COG1217	gtp-binding protein TYPA
J7D54_11205	COG2755	lipolytic protein G-D-S-L family
J7D54_11215	COG2326	polyphosphate kinase activity
J7D54_11220	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J7D54_11230	COG3485	protocatechuate 3,4-dioxygenase
J7D54_11235	COG1490	D-aminoacyl-tRNA deacylase activity
J7D54_11245	COG0745	RESPONSE REGULATOR receiver
J7D54_11250	COG0456	acetyltransferase
J7D54_11255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J7D54_11260	COG0406	alpha-ribazole phosphatase activity
J7D54_11260	COG0494	nUDIX hydrolase
J7D54_11265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J7D54_11280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J7D54_11290	COG2814	Major facilitator Superfamily
J7D54_11300	COG2217	Heavy metal translocating P-type atpase
J7D54_11305	COG1472	Belongs to the glycosyl hydrolase 3 family
J7D54_11315	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_11325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J7D54_11335	COG0785	Cytochrome C biogenesis protein
J7D54_11340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J7D54_11345	COG0406	alpha-ribazole phosphatase activity
J7D54_11365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J7D54_11385	COG1082	Xylose isomerase domain protein TIM barrel
J7D54_11395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J7D54_11405	COG0789	Transcriptional regulator
J7D54_11415	COG1413	lyase activity
J7D54_11425	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
J7D54_11440	COG3842	ATPase activity
J7D54_11450	COG2197	response regulator
J7D54_11465	COG0649	NAD binding
J7D54_11490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J7D54_11495	COG0302	gtp cyclohydrolase
J7D54_11510	COG0037	tRNA processing
J7D54_11525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J7D54_11530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J7D54_11535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J7D54_11585	COG1774	PSP1 C-terminal conserved region
J7D54_11595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J7D54_11600	COG0730	response to heat
J7D54_11605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J7D54_11615	COG1754	DNA topoisomerase type I activity
J7D54_11615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J7D54_11640	COG0667	Aldo Keto reductase
J7D54_11660	COG1111	helicase
J7D54_11660	COG1205	dead DEAH box helicase
J7D54_11725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J7D54_11750	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J7D54_11765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J7D54_11770	COG0673	inositol 2-dehydrogenase activity
J7D54_11775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J7D54_11780	COG0371	Dehydrogenase
J7D54_11785	COG0647	UMP catabolic process
J7D54_11800	COG1131	(ABC) transporter
J7D54_11815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J7D54_11825	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J7D54_11850	COG2056	Na+-H+ antiporter family
J7D54_11885	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J7D54_11905	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J7D54_11930	COG0310	cobalt ion transport
J7D54_11985	COG1492	cobalamin metabolic process
J7D54_11990	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J7D54_12000	COG2813	Specifically methylates the guanine in position
J7D54_12005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J7D54_12010	COG0560	Phosphoserine phosphatase
J7D54_12015	COG2115	Belongs to the xylose isomerase family
J7D54_12025	COG2095	MarC family integral membrane protein
J7D54_12030	COG1473	amidohydrolase
J7D54_12040	COG1793	dna ligase
J7D54_12040	COG3285	dna ligase
J7D54_12060	COG0596	Alpha beta hydrolase
J7D54_12060	COG2945	thiolester hydrolase activity
J7D54_12065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J7D54_12070	COG2011	ABC-type metal ion transport system permease component
J7D54_12075	COG1464	Belongs to the NlpA lipoprotein family
J7D54_12125	COG0205	6-phosphofructokinase activity
J7D54_12145	COG1940	carbohydrate kinase activity
J7D54_12155	COG0018	arginyl-trna synthetase
J7D54_12165	COG1082	Xylose isomerase domain protein TIM barrel
J7D54_12170	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_12175	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_12180	COG1129	ABC transporter
J7D54_12185	COG1879	ABC-type sugar transport system periplasmic component
J7D54_12190	COG1349	DNA-binding transcription factor activity
J7D54_12195	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J7D54_12200	COG0569	domain protein
J7D54_12205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J7D54_12220	COG0166	Belongs to the GPI family
J7D54_12225	COG1316	TRANSCRIPTIONal
J7D54_12230	COG0477	Major facilitator Superfamily
J7D54_12250	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
J7D54_12260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J7D54_12270	COG0444	Belongs to the ABC transporter superfamily
J7D54_12280	COG0747	negative chemotaxis
J7D54_12295	COG0395	ABC-type sugar transport system, permease component
J7D54_12300	COG1175	transmembrane transport
J7D54_12315	COG0673	inositol 2-dehydrogenase activity
J7D54_12320	COG1012	belongs to the aldehyde dehydrogenase family
J7D54_12325	COG1082	Xylose isomerase domain protein TIM barrel
J7D54_12330	COG3962	Belongs to the TPP enzyme family
J7D54_12335	COG3718	enzyme involved in inositol metabolism
J7D54_12345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J7D54_12350	COG2188	Transcriptional regulator
J7D54_12360	COG0673	inositol 2-dehydrogenase activity
J7D54_12380	COG2197	response regulator
J7D54_12400	COG4989	oxidoreductase activity
J7D54_12425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J7D54_12445	COG2211	Major facilitator Superfamily
J7D54_12450	COG3250	beta-galactosidase activity
J7D54_12455	COG1606	tRNA processing
J7D54_12460	COG1691	(AIR) carboxylase
J7D54_12465	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J7D54_12470	COG1609	Transcriptional regulator
J7D54_12475	COG1904	glucuronate isomerase
J7D54_12485	COG0438	transferase activity, transferring glycosyl groups
J7D54_12490	COG0406	alpha-ribazole phosphatase activity
J7D54_12520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J7D54_12540	COG1088	dTDP-glucose 4,6-dehydratase activity
J7D54_12555	COG1716	ATPase activity
J7D54_12575	COG0768	penicillin binding
J7D54_12580	COG0515	serine threonine protein kinase
J7D54_12595	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7D54_12620	COG1621	beta-fructofuranosidase activity
J7D54_12635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J7D54_12640	COG0393	Putative heavy-metal-binding
J7D54_12645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J7D54_12660	COG1175	transmembrane transport
J7D54_12665	COG0395	ABC-type sugar transport system, permease component
J7D54_12675	COG0531	amino acid
J7D54_12685	COG3250	beta-galactosidase activity
J7D54_12700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J7D54_12710	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J7D54_12715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J7D54_12730	COG4122	O-methyltransferase activity
J7D54_12750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J7D54_12755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J7D54_12810	COG1501	Belongs to the glycosyl hydrolase 31 family
J7D54_12815	COG0395	ABC-type sugar transport system, permease component
J7D54_12820	COG1175	transmembrane transport
J7D54_12830	COG1846	Transcriptional regulator
J7D54_12830	COG1940	carbohydrate kinase activity
J7D54_12940	COG2514	catechol 2,3-dioxygenase activity
J7D54_12945	COG2326	polyphosphate kinase activity
J7D54_12955	COG1271	oxidase subunit
J7D54_12960	COG1294	oxidase, subunit
J7D54_12965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J7D54_12970	COG4988	ABC transporter
J7D54_12975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J7D54_12980	COG1929	Belongs to the glycerate kinase type-1 family
J7D54_12990	COG0114	fumarate hydratase activity
J7D54_13005	COG1937	Protein conserved in bacteria
J7D54_13010	COG0305	Participates in initiation and elongation during chromosome replication
J7D54_13015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J7D54_13040	COG1652	LysM domain
J7D54_13050	COG1393	Belongs to the ArsC family
J7D54_13065	COG1597	lipid kinase activity
J7D54_13075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J7D54_13080	COG0515	serine threonine protein kinase
J7D54_13080	COG2815	serine threonine protein kinase
J7D54_13095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J7D54_13105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7D54_13115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J7D54_13135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J7D54_13140	COG4172	Belongs to the ABC transporter superfamily
J7D54_13145	COG4608	Belongs to the ABC transporter superfamily
J7D54_13155	COG1022	Amp-dependent synthetase and ligase
J7D54_13160	COG0488	(ABC) transporter
J7D54_13165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J7D54_13185	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J7D54_13190	COG1070	Carbohydrate kinase
J7D54_13200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J7D54_13200	COG2111	Na H antiporter
J7D54_13205	COG1006	Multisubunit Na H antiporter MnhC subunit
J7D54_13210	COG0651	ATP synthesis coupled electron transport
J7D54_13240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7D54_13255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J7D54_13280	COG3022	response to hydroperoxide
J7D54_13290	COG0733	neurotransmitter:sodium symporter activity
J7D54_13310	COG0574	Belongs to the PEP-utilizing enzyme family
J7D54_13310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J7D54_13315	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J7D54_13330	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J7D54_13345	COG2160	L-arabinose isomerase activity
J7D54_13355	COG1609	Transcriptional regulator
J7D54_13380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J7D54_13390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J7D54_13395	COG0668	transmembrane transport
J7D54_13400	COG0617	tRNA 3'-terminal CCA addition
J7D54_13415	COG3592	Divergent 4Fe-4S mono-cluster
J7D54_13445	COG0596	Alpha beta hydrolase
J7D54_13455	COG1137	ATPase activity
J7D54_13475	COG0318	PFAM AMP-dependent synthetase and ligase
J7D54_13485	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_13490	COG2267	carboxylic ester hydrolase activity
J7D54_13505	COG0183	Belongs to the thiolase family
J7D54_13510	COG0535	radical SAM domain protein
J7D54_13515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J7D54_13535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J7D54_13540	COG1064	alcohol dehydrogenase
J7D54_13600	COG0395	ABC-type sugar transport system, permease component
J7D54_13605	COG1175	transmembrane transport
J7D54_13620	COG1486	melibiose metabolic process
J7D54_13625	COG3588	fructose-bisphosphate aldolase
J7D54_13630	COG0671	phosphoesterase, PA-phosphatase related
J7D54_13655	COG2026	Addiction module toxin, RelE StbE family
J7D54_13660	COG2161	toxin-antitoxin pair type II binding
J7D54_13670	COG2706	6-phosphogluconolactonase activity
J7D54_13720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J7D54_13745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J7D54_13755	COG1737	Transcriptional regulator
J7D54_13760	COG1321	iron dependent repressor
J7D54_13770	COG3119	arylsulfatase activity
J7D54_13775	COG0395	ABC-type sugar transport system, permease component
J7D54_13780	COG1175	transmembrane transport
J7D54_13795	COG1940	carbohydrate kinase activity
J7D54_13820	COG0667	Aldo Keto reductase
J7D54_13825	COG2124	cytochrome p450
J7D54_13825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J7D54_13830	COG0667	Aldo Keto reductase
J7D54_13835	COG3842	ATPase activity
J7D54_13865	COG2409	Drug exporters of the RND superfamily
J7D54_13875	COG0133	tryptophan synthase activity
J7D54_13890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J7D54_13895	COG1272	protein, Hemolysin III
J7D54_13900	COG1131	(ABC) transporter
J7D54_13910	COG4585	Histidine kinase
J7D54_13915	COG2197	response regulator
J7D54_13925	COG3387	PFAM Glycoside hydrolase 15-related
J7D54_13930	COG0667	Aldo Keto reductase
J7D54_13935	COG2226	methyltransferase
J7D54_13940	COG1902	pentaerythritol trinitrate reductase activity
J7D54_13945	COG3459	Glycosyltransferase 36 associated
J7D54_13955	COG1028	Short-chain dehydrogenase reductase Sdr
J7D54_13965	COG4585	Histidine kinase
J7D54_13975	COG1131	(ABC) transporter
J7D54_13995	COG2045	Belongs to the ComB family
J7D54_14040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J7D54_14050	COG1024	Enoyl-CoA hydratase
J7D54_14060	COG0492	ferredoxin-NADP+ reductase activity
J7D54_14065	COG3118	belongs to the thioredoxin family
J7D54_14080	COG1181	Belongs to the D-alanine--D-alanine ligase family
J7D54_14100	COG1192	Involved in chromosome partitioning
J7D54_14105	COG0357	Ribosomal RNA small subunit methyltransferase G
J7D54_14115	COG0706	membrane insertase activity
J7D54_14120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J7D54_14125	COG0594	ribonuclease P activity
J7D54_14130	COG0230	Belongs to the bacterial ribosomal protein bL34 family