locus-tag	class	description
BKM78_00020	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BKM78_00025	ENOG4105CAK	Cell division ATP-binding protein ftsE
BKM78_00035	ENOG4105DR5	peptidase
BKM78_00040	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BKM78_00070	ENOG4105DZR	Type I site-specific deoxyribonuclease
BKM78_00105	ENOG4107R3N	Filamentation induced by cAMP protein fic
BKM78_00120	ENOG4108UJU	UPF0301 protein
BKM78_00125	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BKM78_00130	ENOG4105BZU	Histidine kinase
BKM78_00135	ENOG4108MKR	lipoprotein lpqb
BKM78_00140	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BKM78_00145	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
BKM78_00150	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BKM78_00175	ENOG4105FDF	Could be involved in DNA repair (By similarity)
BKM78_00185	ENOG4105DB7	PHP domain protein
BKM78_00205	ENOG4108ZF3	Phosphatase
BKM78_00215	ENOG4105ENA	helicase
BKM78_00220	ENOG4105C4R	Atp-dependent dna helicase
BKM78_00235	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BKM78_00240	ENOG41080R8	Conserved Protein
BKM78_00245	ENOG4107QR9	Iron-sulfur cluster binding protein
BKM78_00250	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BKM78_00255	ENOG4105DAA	L-lactate
BKM78_00260	ENOG4105EMF	GntR family transcriptional regulator
BKM78_00270	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BKM78_00295	ENOG4107W53	thymidine kinase
BKM78_00320	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BKM78_00340	ENOG4107VEG	TrkA-N domain protein
BKM78_00345	ENOG4105C0X	amino acid
BKM78_00350	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BKM78_00355	ENOG4107QM5	aconitate hydratase
BKM78_00365	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BKM78_00430	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
BKM78_00435	ENOG4108FN7	Aldo keto reductase
BKM78_00455	ENOG4105CI0	Citrate lyase
BKM78_00470	ENOG4107H3J	ribonuclease
BKM78_00490	ENOG4108UW8	fha domain-containing protein
BKM78_00510	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BKM78_00515	ENOG4105E2K	Glycosyl transferase (Group 1
BKM78_00520	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
BKM78_00530	ENOG4105C22	threonyL-tRNA synthetase
BKM78_00540	ENOG4108Z66	YbaK ebsC protein
BKM78_00545	ENOG4107AQZ	Membrane
BKM78_00560	ENOG4105C5Y	PTS System
BKM78_00565	ENOG4107SET	aldo keto reductase
BKM78_00570	ENOG4105CHR	reductase
BKM78_00580	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BKM78_00585	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
BKM78_00595	ENOG4105Q70	
BKM78_00600	ENOG4105FS0	cytoplasmic membrane protein
BKM78_00605	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
BKM78_00615	ENOG4105HFS	5'-3' exonuclease
BKM78_00620	ENOG4105DWV	Homoserine O-trans-acetylase
BKM78_00625	ENOG4105DWV	Homoserine O-trans-acetylase
BKM78_00650	ENOG4105EJQ	L-serine dehydratase
BKM78_00670	ENOG4105BZU	Histidine kinase
BKM78_00675	ENOG4105XEV	csbD-like
BKM78_00690	ENOG4105ECP	epimerase
BKM78_00710	ENOG4105E90	ABC transporter
BKM78_00715	ENOG4105E90	ABC transporter
BKM78_00720	ENOG4108HQR	Glycine betaine
BKM78_00730	ENOG4105CZN	Potassium uptake protein
BKM78_00735	ENOG4105VEQ	Cold shock protein
BKM78_00740	ENOG4107STQ	Multicopper oxidase
BKM78_00745	ENOG4108Z9Z	response to DNA damage stimulus
BKM78_00755	ENOG41067RQ	csbd family
BKM78_00760	ENOG4105CDA	abc transporter atp-binding protein
BKM78_00765	ENOG4107UBR	Extracellular solute-binding protein family 3
BKM78_00770	ENOG4108Q1T	ABC transporter
BKM78_00775	ENOG4105DRP	amino acid AbC transporter
BKM78_00795	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BKM78_00800	ENOG4105CAT	Cytidine monophosphate kinase
BKM78_00815	ENOG4105C3R	Methionine synthase
BKM78_00825	ENOG4105DJV	ribulose-phosphate 3-epimerase
BKM78_00835	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BKM78_00845	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BKM78_00850	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BKM78_00855	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BKM78_00865	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
BKM78_00870	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BKM78_00875	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BKM78_00880	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BKM78_00885	ENOG410803B	Involved in the transcription termination process (By similarity)
BKM78_00890	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BKM78_00895	ENOG4105D49	3-dehydroquinate synthase
BKM78_00900	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BKM78_00905	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BKM78_00910	ENOG4105E2X	shikimate dehydrogenase
BKM78_00920	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BKM78_00925	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BKM78_00945	ENOG4105C2C	drug resistance transporter, Bcr CflA
BKM78_00950	ENOG4105C9M	aspartyl-trna synthetase
BKM78_00955	ENOG4105CUT	histidyl-tRNA synthetase
BKM78_00960	ENOG4105C5X	domain protein
BKM78_00965	ENOG4105C99	atpase involved in dna repair
BKM78_00970	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BKM78_00980	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BKM78_00985	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BKM78_00990	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BKM78_01005	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BKM78_01010	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BKM78_01015	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BKM78_01020	ENOG4105CDY	transcriptional regulatory protein
BKM78_01045	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BKM78_01050	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BKM78_01055	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BKM78_01060	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BKM78_01065	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BKM78_01075	ENOG4105C0B	DNA polymerase III (alpha subunit)
BKM78_01080	ENOG4107WGA	YidE YbjL
BKM78_01095	ENOG4105CBC	glutamate synthase
BKM78_01100	ENOG4108IUK	alpha amylase, catalytic
BKM78_01110	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BKM78_01115	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BKM78_01120	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BKM78_01140	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BKM78_01185	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
BKM78_01190	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BKM78_01195	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BKM78_01200	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BKM78_01220	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BKM78_01240	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BKM78_01250	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BKM78_01260	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BKM78_01305	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
BKM78_01315	ENOG4105EV9	Alpha Beta Hydrolase
BKM78_01335	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BKM78_01340	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BKM78_01345	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BKM78_01350	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BKM78_01355	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BKM78_01360	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BKM78_01365	ENOG4105ZA1	atp synthase
BKM78_01370	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
BKM78_01385	ENOG4105ESV	Glycosyl transferase, family 4
BKM78_01395	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BKM78_01400	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BKM78_01405	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BKM78_01410	ENOG41085W3	Transposase
BKM78_01420	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BKM78_01425	ENOG4105D6E	homoserine dehydrogenase
BKM78_01450	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BKM78_01460	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BKM78_01490	ENOG4105EMN	RNA polymerase sigma factor
BKM78_01495	ENOG4108RAV	Conserved protein
BKM78_01505	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BKM78_01510	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BKM78_01515	ENOG4107TK4	histidinol-phosphate phosphatase
BKM78_01520	ENOG4108JQ1	Dehydrogenase
BKM78_01525	ENOG4108JQ7	(ABC) transporter
BKM78_01535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BKM78_01545	ENOG4105DEF	Extracellular solute-binding protein, family 5
BKM78_01560	ENOG4107SET	aldo keto reductase
BKM78_01580	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BKM78_01585	ENOG4105CVJ	phosphoglycerate mutase
BKM78_01590	ENOG4105CTK	cobaltochelatase, cobn subunit
BKM78_01600	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BKM78_01610	ENOG4108YZT	Adenosylcobinamide kinase
BKM78_01650	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BKM78_01665	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
BKM78_01695	ENOG4105CPC	Aldo Keto reductase
BKM78_01715	ENOG4105DJZ	UPF0182 protein
BKM78_01745	ENOG4105DSY	exodeoxyribonuclease V, gamma
BKM78_01760	ENOG4105CGF	Aromatic amino acid aminotransferase
BKM78_01765	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
BKM78_01775	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BKM78_01785	ENOG4105C29	acyl-CoA thioesterase
BKM78_01790	ENOG4105CQ7	ATP-dependent helicase
BKM78_01820	ENOG4107QUT	magnesium and cobalt transport protein CorA
BKM78_01825	ENOG4105C01	Dihydroxy-acid dehydratase
BKM78_01830	ENOG4105KHC	sulfurtransferase
BKM78_01835	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BKM78_01845	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BKM78_01850	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BKM78_01860	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BKM78_01870	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BKM78_01875	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BKM78_01880	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BKM78_01890	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BKM78_01895	ENOG4107WI4	Aldose-1-epimerase
BKM78_01900	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BKM78_01905	ENOG4105KC9	Modulates RecA activity (By similarity)
BKM78_01910	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BKM78_01920	ENOG4105E98	transcriptional regulator DeoR family
BKM78_01925	ENOG4105WBV	Transcriptional regulator
BKM78_01930	ENOG4105CEV	competence damage-inducible protein
BKM78_01940	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BKM78_01955	ENOG4105CPF	Cell wall formation (By similarity)
BKM78_01990	ENOG4105K5B	UPF0225 protein
BKM78_02000	ENOG4108X4Q	Hydrolase
BKM78_02010	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BKM78_02025	ENOG4105C3J	Cysteine desulfurase
BKM78_02030	ENOG4105NAE	bifunctional deaminase-reductase domain protein
BKM78_02060	ENOG4107SNB	ankyrin repeat protein YahD
BKM78_02100	ENOG4108RWI	nicotinamidase
BKM78_02110	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BKM78_02200	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
BKM78_02205	ENOG4105CMT	Dihydroxyacetone kinase
BKM78_02240	ENOG4107ZR7	Membrane
BKM78_02260	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BKM78_02265	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BKM78_02270	ENOG41069M3	Transcriptional regulator
BKM78_02290	ENOG4107FCW	Abortive infection protein
BKM78_02295	ENOG4105ERH	Fumarylacetoacetate hydrolase
BKM78_02300	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BKM78_02305	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BKM78_02315	ENOG4105CTS	PTS system mannitol-specific
BKM78_02320	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BKM78_02325	ENOG4108ZP8	Acetolactate synthase small subunit
BKM78_02345	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BKM78_02350	ENOG4105CQR	helicase
BKM78_02360	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BKM78_02365	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BKM78_02380	ENOG4108FFZ	Transcriptional regulator
BKM78_02385	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BKM78_02390	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BKM78_02400	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BKM78_02405	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BKM78_02430	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BKM78_02435	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BKM78_02440	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BKM78_02490	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BKM78_02495	ENOG4105CH7	arginosuccinase
BKM78_02500	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
BKM78_02510	ENOG4105CAS	nag kinase
BKM78_02515	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BKM78_02520	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BKM78_02540	ENOG4105CK7	Sodium proline symporter
BKM78_02545	ENOG4107RCC	Major Facilitator Superfamily
BKM78_02550	ENOG4106A3M	Cytochrome p-450
BKM78_02565	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BKM78_02570	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BKM78_02575	ENOG4108RWN	rrna methyltransferase
BKM78_02580	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BKM78_02585	ENOG41084BS	50S ribosomal protein L35
BKM78_02590	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BKM78_02610	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BKM78_02615	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
BKM78_02620	ENOG4105C8N	cysteinyl-tRNA synthetase
BKM78_02640	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BKM78_02645	ENOG4108FN7	Aldo keto reductase
BKM78_02660	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BKM78_02665	ENOG4105NAF	rna polymerase sigma factor
BKM78_02675	ENOG41085W3	Transposase
BKM78_02705	ENOG4105CVR	type I restriction-modification system
BKM78_02810	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BKM78_02825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BKM78_02830	ENOG4105BZU	Histidine kinase
BKM78_02855	ENOG4105PGM	cation diffusion facilitator family transporter
BKM78_02860	ENOG4107ZT5	Thiol disulfide interchange protein
BKM78_02865	ENOG4107QIV	Cytochrome c biogenesis protein
BKM78_02885	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BKM78_02890	ENOG4105EB3	Histidine kinase
BKM78_02935	ENOG4105MP0	transposase
BKM78_02940	ENOG4105C59	p-type ATPase
BKM78_02945	ENOG4105VPX	protein, conserved in bacteria
BKM78_02970	ENOG4108JQ6	ABC transporter
BKM78_02975	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BKM78_03010	ENOG4108C33	Resolvase
BKM78_03045	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BKM78_03060	ENOG4105CG3	alpha amylase, catalytic region
BKM78_03085	ENOG4107VXZ	Hydrolase
BKM78_03105	ENOG4105BZ1	(ABC) transporter
BKM78_03120	ENOG4105C79	DNA protecting protein DprA
BKM78_03125	ENOG4105C0P	Mg chelatase subunit ChlI
BKM78_03130	ENOG41080R2	UPF0102 protein
BKM78_03140	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BKM78_03150	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BKM78_03155	ENOG4105E33	succinate dehydrogenase
BKM78_03170	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BKM78_03175	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BKM78_03180	ENOG41082KU	UPF0109 protein
BKM78_03185	ENOG4105K5M	30s ribosomal protein S16
BKM78_03210	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BKM78_03215	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BKM78_03220	ENOG4108ZGX	Histidine kinase
BKM78_03225	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_03235	ENOG4105DA5	(ABC) transporter
BKM78_03250	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BKM78_03260	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BKM78_03265	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BKM78_03270	ENOG41084BZ	50S ribosomal protein L32
BKM78_03285	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BKM78_03290	ENOG4106H78	methyltransferase
BKM78_03295	ENOG4105CB5	ATP-dependent DNA helicase recG
BKM78_03300	ENOG4105VB9	50S ribosomal protein l28
BKM78_03305	ENOG4105C03	ribonuclease
BKM78_03315	ENOG4105DPH	UPF0371 protein
BKM78_03325	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BKM78_03335	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BKM78_03345	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BKM78_03350	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BKM78_03355	ENOG41060NJ	transcriptional regulator
BKM78_03360	ENOG4105QE3	oxidoreductase
BKM78_03365	ENOG4107RE3	peptidase, S41
BKM78_03370	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
BKM78_03375	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BKM78_03380	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BKM78_03385	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BKM78_03390	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BKM78_03450	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BKM78_03465	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BKM78_03470	ENOG4105CXT	aspartate transcarbamylase
BKM78_03475	ENOG4105CD3	dihydroorotase
BKM78_03490	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BKM78_03500	ENOG4107QRT	dEAD DEAH box helicase
BKM78_03505	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
BKM78_03510	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_03525	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BKM78_03530	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BKM78_03540	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BKM78_03550	ENOG4106Z5D	Glycoside Hydrolase Family 43
BKM78_03555	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_03560	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
BKM78_03585	ENOG4105CQB	FAD linked oxidase domain protein
BKM78_03610	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BKM78_03635	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BKM78_03655	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BKM78_03675	ENOG4108KGH	TRANSCRIPTIONal
BKM78_03690	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BKM78_03720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BKM78_03725	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BKM78_03735	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BKM78_03740	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BKM78_03745	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BKM78_03750	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BKM78_03760	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BKM78_03800	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BKM78_03810	ENOG4105W49	UPF0434 protein
BKM78_03840	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
BKM78_03870	ENOG4108RCF	TRANSCRIPTIONal
BKM78_03875	ENOG4108KGH	TRANSCRIPTIONal
BKM78_03900	ENOG4105D8K	carboxyl transferase
BKM78_03910	ENOG4107WR6	Maf-like protein
BKM78_03925	ENOG4108JIK	carboxylase
BKM78_03945	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
BKM78_03960	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BKM78_03975	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_03995	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
BKM78_04010	ENOG4105UIB	(ABC) transporter
BKM78_04015	ENOG4108JQ9	ABC transporter
BKM78_04020	ENOG4105DIH	basic membrane
BKM78_04045	ENOG4107QN1	sodium solute
BKM78_04050	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BKM78_04065	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BKM78_04070	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BKM78_04095	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BKM78_04110	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BKM78_04120	ENOG4105Y3U	Transglycosylase-associated protein
BKM78_04125	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_04150	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BKM78_04160	ENOG4105E9Z	Nad-dependent epimerase dehydratase
BKM78_04170	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
BKM78_04175	ENOG4107QVP	Dehydrogenase
BKM78_04180	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BKM78_04185	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BKM78_04190	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BKM78_04195	ENOG4108UW5	maltose o-acetyltransferase
BKM78_04210	ENOG4108JQ6	ABC transporter
BKM78_04225	ENOG4108NY6	Extracellular solute-binding protein, family 5
BKM78_04230	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BKM78_04245	ENOG4108097	ATP-binding protein
BKM78_04250	ENOG4105C1J	atp-dependent rna helicase
BKM78_04260	ENOG4105CJQ	hydrolase, family 31
BKM78_04270	ENOG4105DBE	peroxidase
BKM78_04280	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BKM78_04285	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BKM78_04290	ENOG4105CS9	pantothenic acid kinase
BKM78_04295	ENOG4107T6F	Xaa-Pro aminopeptidase
BKM78_04315	ENOG4105CI0	Citrate lyase
BKM78_04320	ENOG4105CJW	magnesium transporter
BKM78_04340	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BKM78_04355	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BKM78_04360	ENOG4107ZBN	O-methyltransferase
BKM78_04365	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BKM78_04370	ENOG4107QPH	glycogen) synthase
BKM78_04385	ENOG4108URH	decarboxylase
BKM78_04390	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
BKM78_04410	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
BKM78_04420	ENOG4105BZ1	(ABC) transporter
BKM78_04425	ENOG4105BZ1	(ABC) transporter
BKM78_04435	ENOG4105DRS	transport system, permease
BKM78_04455	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_04465	ENOG4108Z4U	Ferredoxin
BKM78_04475	ENOG4105D07	Signal peptide peptidase, SppA
BKM78_04485	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
BKM78_04505	ENOG4108RWI	nicotinamidase
BKM78_04515	ENOG4105D7W	serine acetyltransferase
BKM78_04555	ENOG4105C3G	gtp-binding protein
BKM78_04565	ENOG4105DFM	M18 family aminopeptidase
BKM78_04585	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BKM78_04595	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BKM78_04600	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BKM78_04610	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BKM78_04620	ENOG4108IAB	Phoh family
BKM78_04640	ENOG4105C7Z	Conserved Protein
BKM78_04655	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BKM78_04670	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BKM78_04675	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BKM78_04685	ENOG4105CGZ	zinc metallopeptidase
BKM78_04725	ENOG4105DZ6	Band 7 protein
BKM78_04745	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BKM78_04765	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BKM78_04770	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BKM78_04790	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BKM78_04795	ENOG4105I1K	ABC transporter
BKM78_04800	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_04835	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BKM78_04845	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BKM78_04850	ENOG4107U1N	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BKM78_04860	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_04870	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BKM78_04875	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_04890	ENOG4105EPC	oxidoreductase
BKM78_04910	ENOG4108R3E	Dna-3-methyladenine glycosylase i
BKM78_04930	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BKM78_04935	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BKM78_04940	ENOG4105F8V	Hydrolase, tatD family
BKM78_04960	ENOG4105C2W	permease
BKM78_04970	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BKM78_04990	ENOG4107RK0	Sucrose phosphorylase
BKM78_05075	ENOG4107QZF	nitrite reductase NADPH large subunit
BKM78_05080	ENOG4107QZF	nitrite reductase NADPH large subunit
BKM78_05085	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BKM78_05090	ENOG4107QND	Nitrite extrusion protein
BKM78_05110	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BKM78_05115	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BKM78_05120	ENOG4105BZ8	glutamate synthase
BKM78_05140	ENOG41080RH	Thioredoxin
BKM78_05145	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BKM78_05155	ENOG4105CE4	GlcNAc 6-P deacetylase
BKM78_05160	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BKM78_05175	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
BKM78_05180	ENOG4105C7N	Xanthine uracil vitamin C permease
BKM78_05190	ENOG4105VEQ	Cold shock protein
BKM78_05195	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BKM78_05205	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BKM78_05220	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BKM78_05235	ENOG4105EIP	mannose-6-phosphate isomerase
BKM78_05255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BKM78_05260	ENOG4105C28	cystathionine
BKM78_05270	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BKM78_05275	ENOG4105C8N	cysteinyl-tRNA synthetase
BKM78_05280	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BKM78_05285	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BKM78_05290	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BKM78_05295	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BKM78_05300	ENOG4108VJ1	Transcriptional regulator (CarD family
BKM78_05315	ENOG4105BZU	Histidine kinase
BKM78_05325	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BKM78_05340	ENOG4108JB8	alcohol dehydrogenase
BKM78_05350	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
BKM78_05360	ENOG4107QX3	carboxylase
BKM78_05365	ENOG4107QSA	Oxaloacetate decarboxylase
BKM78_05370	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BKM78_05390	ENOG4105DY9	regulatoR
BKM78_05400	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
BKM78_05430	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
BKM78_05440	ENOG4105CPP	Dehydrogenase, E1 component
BKM78_05445	ENOG4107QN2	dihydrolipoyl dehydrogenase
BKM78_05450	ENOG4107QKR	Dehydrogenase
BKM78_05455	ENOG4105N2W	Transcriptional regulator
BKM78_05470	ENOG4105DIQ	Transcriptional regulator
BKM78_05475	ENOG4105C2J	ABC transporter
BKM78_05480	ENOG4105CNN	ABC, transporter
BKM78_05500	ENOG4108R85	Short chain dehydrogenase
BKM78_05505	ENOG4105CS9	pantothenic acid kinase
BKM78_05510	ENOG4105DEI	Mannitol dehydrogenase
BKM78_05515	ENOG4107QKS	N-acylglucosamine 2-epimerase
BKM78_05520	ENOG410667J	hydrolase
BKM78_05545	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BKM78_05550	ENOG41085GJ	domain protein
BKM78_05555	ENOG4108VCT	Sulfite exporter TauE/SafE
BKM78_05560	ENOG4105KBH	arsR family transcriptional regulator
BKM78_05585	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_05595	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
BKM78_05605	ENOG4105CNN	ABC, transporter
BKM78_05620	ENOG4107RCW	fructose-bisphosphate aldolase
BKM78_05645	ENOG4108YYC	ycei family
BKM78_05650	ENOG4108V0P	LemA family
BKM78_05665	ENOG4107QP3	malate synthase g
BKM78_05670	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BKM78_05680	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
BKM78_05690	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BKM78_05695	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BKM78_05705	ENOG4108JJB	ABC transporter
BKM78_05720	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BKM78_05745	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
BKM78_05750	ENOG4105CIK	Amidinotransferase
BKM78_05755	ENOG4105C8Y	Acetylornithine aminotransferase
BKM78_05765	ENOG4105E4R	Precorrin-3B C17-methyltransferase
BKM78_05770	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
BKM78_05780	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BKM78_05785	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BKM78_05810	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BKM78_05820	ENOG4105C37	(CBS) domain
BKM78_05830	ENOG41082SX	arsR family transcriptional regulator
BKM78_05850	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_05865	ENOG4105CNT	hydrolase family 2
BKM78_05870	ENOG4107KJX	Transcriptional regulator
BKM78_05885	ENOG4105I1K	ABC transporter
BKM78_05915	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BKM78_05975	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BKM78_05990	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BKM78_05995	ENOG4105CG3	alpha amylase, catalytic region
BKM78_06020	ENOG4105CPQ	Dehydrogenase
BKM78_06025	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BKM78_06040	ENOG4105DWF	phosphomethylpyrimidine kinase
BKM78_06050	ENOG4105DWF	phosphomethylpyrimidine kinase
BKM78_06060	ENOG4105E0A	ABC, transporter
BKM78_06065	ENOG4105TVJ	transport system, permease
BKM78_06070	ENOG4105DQ5	transport system permease protein
BKM78_06090	ENOG4105KNI	merR family transcriptional Regulator
BKM78_06095	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BKM78_06100	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKM78_06105	ENOG4105CFG	Acts as a chaperone (By similarity)
BKM78_06115	ENOG4105D7Z	glutathione synthase
BKM78_06130	ENOG4105D98	threonine synthase
BKM78_06145	ENOG41090CE	integral membrane protein
BKM78_06155	ENOG4105CEP	NADH dehydrogenase
BKM78_06165	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BKM78_06170	ENOG4105BZU	Histidine kinase
BKM78_06175	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BKM78_06185	ENOG4105DHP	deoxycytidine triphosphate deaminase
BKM78_06200	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BKM78_06210	ENOG4108YXG	UPF0502 protein
BKM78_06215	ENOG4105CFH	Aspartokinase
BKM78_06225	ENOG4105D7A	ATP-binding protein
BKM78_06250	ENOG4108Z6B	deaminase
BKM78_06260	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BKM78_06270	ENOG4107SIQ	Naphthoate synthase
BKM78_06275	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BKM78_06280	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BKM78_06300	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BKM78_06310	ENOG4108KGH	TRANSCRIPTIONal
BKM78_06330	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_06335	ENOG4105D4B	ABC, transporter
BKM78_06340	ENOG4105C2J	ABC transporter
BKM78_06345	ENOG4105CNN	ABC, transporter
BKM78_06350	ENOG4105CNN	ABC, transporter
BKM78_06355	ENOG4107TRE	AP endonuclease, family 2
BKM78_06375	ENOG4105C34	Pseudouridine synthase
BKM78_06390	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BKM78_06395	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BKM78_06405	ENOG4108IJ1	Dehydrogenase
BKM78_06430	ENOG4105EY8	ABC transporter
BKM78_06465	ENOG4105CDH	Citrulline--aspartate ligase
BKM78_06485	ENOG4108KP7	hydrolase
BKM78_06490	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BKM78_06500	ENOG4107TE5	Lipid kinase
BKM78_06530	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BKM78_06535	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
BKM78_06540	ENOG4105CPP	Dehydrogenase, E1 component
BKM78_06550	ENOG4105CGH	5'-nucleotidase
BKM78_06555	ENOG4105DBV	ornithine carbamoyltransferase
BKM78_06630	ENOG4105E0A	ABC, transporter
BKM78_06645	ENOG4106F60	Histidine kinase
BKM78_06650	ENOG4105ETX	regulatoR
BKM78_06660	ENOG4105CJ1	ABC, transporter
BKM78_06670	ENOG4105D9P	serine threonine protein kinase
BKM78_06695	ENOG4105CEY	Amp-dependent synthetase and ligase
BKM78_06705	ENOG4105WKW	Pfam:DUF1458
BKM78_06715	ENOG4105C0D	helicase
BKM78_06725	ENOG4105CPK	Glycosyl transferase (Group 1
BKM78_06745	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BKM78_06755	ENOG41060NJ	transcriptional regulator
BKM78_06765	ENOG4105CQB	FAD linked oxidase domain protein
BKM78_06780	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
BKM78_06805	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
BKM78_06830	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BKM78_06835	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BKM78_06840	ENOG4105CNN	ABC, transporter
BKM78_06855	ENOG4108IUS	Transketolase
BKM78_06860	ENOG4108HHA	Transketolase
BKM78_06865	ENOG4107Z96	xylose isomerase
BKM78_06870	ENOG4108RVA	ribokinase
BKM78_06875	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
BKM78_06885	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BKM78_06890	ENOG4105BZU	Histidine kinase
BKM78_06910	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
BKM78_06930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BKM78_06935	ENOG4105BZU	Histidine kinase
BKM78_06945	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_06950	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BKM78_06960	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BKM78_07000	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BKM78_07005	ENOG4105D9R	oxidoreductase
BKM78_07030	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BKM78_07040	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
BKM78_07050	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BKM78_07055	ENOG4108IQE	Amp-dependent synthetase and ligase
BKM78_07065	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BKM78_07070	ENOG4105FKQ	transcriptional regulator
BKM78_07080	ENOG4105D65	subunit l
BKM78_07085	ENOG4105MKQ	Monovalent cation H antiporter subunit C
BKM78_07090	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BKM78_07110	ENOG4105DEN	Luciferase family
BKM78_07115	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BKM78_07125	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BKM78_07130	ENOG4108IXY	short-chain dehydrogenase reductase
BKM78_07145	ENOG4105D1Q	UPF0246 protein
BKM78_07150	ENOG4105C8J	)-transporter
BKM78_07160	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BKM78_07165	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BKM78_07175	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BKM78_07185	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BKM78_07225	ENOG4105BZ4	penicillin-binding protein
BKM78_07230	ENOG4105D8X	mechanosensitive ion channel
BKM78_07255	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BKM78_07260	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BKM78_07270	ENOG4105EYF	MMPL domain protein
BKM78_07280	ENOG4105C5X	domain protein
BKM78_07285	ENOG4105CMR	udp-glucose 4-epimerase
BKM78_07290	ENOG4105BZU	Histidine kinase
BKM78_07295	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_07315	ENOG4105KPY	Small multidrug resistance protein
BKM78_07320	ENOG41080TC	multidrug resistance protein
BKM78_07345	ENOG4105MC2	DSBA oxidoreductase
BKM78_07350	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
BKM78_07365	ENOG4105CKW	Inner membrane protein yedI
BKM78_07400	ENOG4107SM8	Adenylate Guanylate cyclase
BKM78_07410	ENOG4108UDB	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
BKM78_07480	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BKM78_07485	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BKM78_07490	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BKM78_07495	ENOG4108KQ5	Integrase catalytic subunit
BKM78_07505	ENOG4105CNT	hydrolase family 2
BKM78_07525	ENOG4105DDV	Transcriptional regulator (LacI family
BKM78_07570	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
BKM78_07595	ENOG4107REC	cytoplasmic protein
BKM78_07600	ENOG4107R1Q	Membrane protein FdrA
BKM78_07610	ENOG4107SNB	ankyrin repeat protein YahD
BKM78_07615	ENOG4105C5B	carbamate kinase
BKM78_07620	ENOG4105DRR	Transcriptional regulator, GntR family
BKM78_07635	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BKM78_07650	ENOG4108KQ5	Integrase catalytic subunit
BKM78_07660	ENOG4107SET	aldo keto reductase
BKM78_07670	ENOG4105EYW	Ion transport protein
BKM78_07675	ENOG41085W3	Transposase
BKM78_07695	ENOG4105EG2	ABC transporter, permease
BKM78_07700	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BKM78_07710	ENOG4105C9B	Cysteine desulfurase
BKM78_07730	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
BKM78_07735	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
BKM78_07740	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BKM78_07745	ENOG4105CNN	ABC, transporter
BKM78_07765	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
BKM78_07790	ENOG4108SKZ	Patatin-like phospholipase
BKM78_07800	ENOG4107S2Z	UPF0761 membrane protein
BKM78_07845	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_07870	ENOG4105GVF	(ABC) transporter
BKM78_07875	ENOG4105E2Y	ABC, transporter
BKM78_07895	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_07920	ENOG4105CHR	reductase
BKM78_07930	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BKM78_07935	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
BKM78_07950	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
BKM78_07955	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BKM78_07970	ENOG4105DR5	peptidase
BKM78_07980	ENOG4105K7N	UPF0232 protein
BKM78_07985	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BKM78_07990	ENOG4108J5G	6-phosphogluconate dehydrogenase
BKM78_07995	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BKM78_08000	ENOG4107R34	abc transporter permease protein
BKM78_08005	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BKM78_08015	ENOG4105VPX	protein, conserved in bacteria
BKM78_08020	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BKM78_08025	ENOG41084CH	50S ribosomal protein l34
BKM78_08030	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BKM78_08035	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BKM78_08040	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BKM78_08050	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BKM78_08055	ENOG4107QJE	Chromosome Partitioning Protein
BKM78_08075	ENOG4105CPF	Cell wall formation (By similarity)
BKM78_08090	ENOG4105K63	Thioredoxin
BKM78_08095	ENOG4105C3M	thioredoxin reductase
BKM78_08100	ENOG4105E39	Enoyl-CoA hydratase
BKM78_08135	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
BKM78_08170	ENOG4107R28	alpha amylase, catalytic region
BKM78_08250	ENOG4108KQ5	Integrase catalytic subunit
BKM78_08255	ENOG4105EYF	MMPL domain protein
BKM78_08290	ENOG4108QGH	periplasmic
BKM78_08295	ENOG4105C2J	ABC transporter
BKM78_08305	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_08310	ENOG4105D9P	serine threonine protein kinase
BKM78_08325	ENOG4105C2J	ABC transporter
BKM78_08340	ENOG4105D4B	ABC, transporter
BKM78_08345	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BKM78_08350	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
BKM78_08355	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
BKM78_08360	ENOG4105DU1	integral membrane protein, terc
BKM78_08380	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BKM78_08420	ENOG4105DIM	ABC transporter
BKM78_08425	ENOG4105CIG	ABC transporter
BKM78_08430	ENOG4108X07	Tetr family transcriptional regulator
BKM78_08435	ENOG410849S	phosphocarrier protein (HPr)
BKM78_08440	ENOG4105DE4	1-phosphofructokinase
BKM78_08445	ENOG4105E98	transcriptional regulator DeoR family
BKM78_08450	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BKM78_08455	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
BKM78_08470	ENOG4105JXH	GntR family transcriptional regulator
BKM78_08480	ENOG4105ZXK	Dehydrogenase
BKM78_08485	ENOG4105C6Z	Gluconate
BKM78_08520	ENOG4107SET	aldo keto reductase
BKM78_08525	ENOG4105VMP	Transcriptional regulator
BKM78_08540	ENOG4108Z5K	methylglyoxal synthase
BKM78_08545	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BKM78_08550	ENOG4105DKQ	ROK family
BKM78_08560	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BKM78_08565	ENOG4105CPC	Aldo Keto reductase
BKM78_08575	ENOG4105CE1	Ferrous iron transport protein b
BKM78_08590	ENOG4107ZXI	Rhomboid family
BKM78_08655	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BKM78_08680	ENOG4105DFW	ABC transporter
BKM78_08685	ENOG4107RNG	ABC transporter
BKM78_08695	ENOG4105DFW	ABC transporter
BKM78_08730	ENOG4105BZ1	(ABC) transporter
BKM78_08735	ENOG4105IJJ	transcriptional regulator, crp fnr family
BKM78_08755	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BKM78_08760	ENOG4108RYK	Nad-dependent epimerase dehydratase
BKM78_08765	ENOG4107GFK	fumarate
BKM78_08785	ENOG4105ED2	Beta-lactamase
BKM78_08790	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BKM78_08805	ENOG4108UZX	fmn reductase
BKM78_08815	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
BKM78_08830	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BKM78_08855	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
BKM78_08880	ENOG4105DCF	alanine dehydrogenase
BKM78_08885	ENOG4105K6T	rare lipoprotein A
BKM78_08895	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BKM78_08910	ENOG4105DSG	hydrolase family 43
BKM78_08915	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BKM78_08920	ENOG41060NJ	transcriptional regulator
BKM78_08925	ENOG4105CJQ	hydrolase, family 31
BKM78_08945	ENOG4105CPK	Glycosyl transferase (Group 1
BKM78_08955	ENOG4105EY8	ABC transporter
BKM78_08990	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BKM78_09030	ENOG4105CDU	Replicative dna helicase
BKM78_09035	ENOG4105VPX	protein, conserved in bacteria
BKM78_09050	ENOG4105C9Q	fumarate hydratase class II
BKM78_09055	ENOG4107V8I	Glycosyl transferases group 1
BKM78_09060	ENOG4105BZW	Glycerate kinase
BKM78_09065	ENOG4108JJ9	ABC, transporter
BKM78_09075	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BKM78_09080	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BKM78_09090	ENOG4105CSR	polyphosphate kinase 2
BKM78_09100	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BKM78_09110	ENOG4105C93	Xylose Isomerase
BKM78_09140	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
BKM78_09170	ENOG4105CNT	hydrolase family 2
BKM78_09195	ENOG4108IYU	L-aspartate oxidase
BKM78_09200	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BKM78_09215	ENOG4105DRS	transport system, permease
BKM78_09220	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BKM78_09235	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_09265	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
BKM78_09290	ENOG4105CJN	penicillin-binding protein
BKM78_09310	ENOG4105TV9	FHA Domain-Containing protein
BKM78_09325	ENOG4105EXC	Acyl-transferase
BKM78_09330	ENOG4107Y2X	deaminase
BKM78_09335	ENOG4105CPQ	Dehydrogenase
BKM78_09340	ENOG4105DKT	Transcriptional regulator
BKM78_09350	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BKM78_09360	ENOG4105D5P	Methylmalonyl-coA mutase
BKM78_09365	ENOG4105CMN	Methylmalonyl-coA mutase
BKM78_09370	ENOG4105EEI	dihydropteroate synthase
BKM78_09385	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BKM78_09400	ENOG4105DH8	myo-inositol catabolism
BKM78_09405	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
BKM78_09410	ENOG4105C26	Dehydrogenase
BKM78_09420	ENOG41082T9	Membrane
BKM78_09440	ENOG4108TGR	phosphatase
BKM78_09445	ENOG4105CNN	ABC, transporter
BKM78_09450	ENOG4105C2J	ABC transporter
BKM78_09460	ENOG4105F0H	myo-inositol catabolism protein
BKM78_09465	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BKM78_09485	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BKM78_09490	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BKM78_09500	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BKM78_09505	ENOG4105EMF	GntR family transcriptional regulator
BKM78_09510	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
BKM78_09520	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BKM78_09530	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BKM78_09540	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_09545	ENOG4107QM2	Aldo Keto reductase
BKM78_09585	ENOG4107UNZ	domain protein
BKM78_09620	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BKM78_09625	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BKM78_09640	ENOG410667J	hydrolase
BKM78_09645	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
BKM78_09655	ENOG4105DU1	integral membrane protein, terc
BKM78_09670	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BKM78_09675	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BKM78_09690	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BKM78_09695	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BKM78_09755	ENOG41085W3	Transposase
BKM78_09800	ENOG4105CJ1	ABC, transporter
BKM78_09830	ENOG4108Z0Z	intracellular protease Pfpi family
BKM78_09840	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BKM78_09855	ENOG41066YJ	Beta-lactamase
BKM78_09880	ENOG4108V06	Glutathione peroxidase
BKM78_09890	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_09900	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BKM78_09905	ENOG4105DRS	transport system, permease
BKM78_09910	ENOG4108JE9	extracellular solute-binding protein family 1
BKM78_09945	ENOG4105C6F	GntR Family Transcriptional Regulator
BKM78_09950	ENOG4105DEF	Extracellular solute-binding protein, family 5
BKM78_09970	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BKM78_09975	ENOG4105DKQ	ROK family
BKM78_09980	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BKM78_09990	ENOG4105EG2	ABC transporter, permease
BKM78_09995	ENOG4105D56	permease protein
BKM78_10010	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_10030	ENOG4108HKT	sucrose-6-phosphate hydrolase
BKM78_10040	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BKM78_10050	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_10070	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
BKM78_10075	ENOG4105EYF	MMPL domain protein
BKM78_10085	ENOG4105CGK	Exodeoxyribonuclease III
BKM78_10095	ENOG4107TPY	serine threonine protein kinase
BKM78_10105	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_10120	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BKM78_10150	ENOG4105DXI	Major Facilitator superfamily
BKM78_10170	ENOG41080RH	Thioredoxin
BKM78_10185	ENOG4108KGH	TRANSCRIPTIONal
BKM78_10195	ENOG41079KZ	Major Facilitator Superfamily
BKM78_10220	ENOG4107QP8	phosphohexose isomerase
BKM78_10230	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BKM78_10255	ENOG4105C75	arginyL-tRNA synthetase
BKM78_10280	ENOG4105CTQ	phosphohexokinase
BKM78_10285	ENOG4105CQB	FAD linked oxidase domain protein
BKM78_10305	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BKM78_10315	ENOG4107XGZ	Hydrolase
BKM78_10320	ENOG4105D01	(LipO)protein
BKM78_10325	ENOG4108UMI	ABC transporter, permease
BKM78_10330	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BKM78_10355	ENOG4105CH2	amidohydrolase
BKM78_10360	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BKM78_10370	ENOG4105CVJ	phosphoglycerate mutase
BKM78_10385	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
BKM78_10395	ENOG4108YZT	Adenosylcobinamide kinase
BKM78_10435	ENOG4105D3Y	Na H antiporter
BKM78_10460	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BKM78_10470	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BKM78_10480	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BKM78_10490	ENOG4105CJ1	ABC, transporter
BKM78_10505	ENOG4105CHH	sulfate transporter
BKM78_10510	ENOG4105C6K	Malic enzyme
BKM78_10515	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BKM78_10520	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BKM78_10535	ENOG410787A	Pts system, glucitol sorbitol-specific
BKM78_10540	ENOG4105DZY	Pts system, glucitol sorbitol-specific
BKM78_10550	ENOG4108MDK	Dehydrogenase
BKM78_10555	ENOG4105KRI	phosphocarrier protein (HPr
BKM78_10560	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BKM78_10565	ENOG4105EE0	oxidoreductase
BKM78_10580	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
BKM78_10600	ENOG4107RGJ	metallophosphoesterase
BKM78_10605	ENOG4105BZ4	penicillin-binding protein
BKM78_10665	ENOG4108ZJ4	polysaccharide deacetylase
BKM78_10670	ENOG4108I5C	dEAD DEAH box helicase
BKM78_10690	ENOG4105CPC	Aldo Keto reductase
BKM78_10700	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BKM78_10710	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BKM78_10715	ENOG4105C6E	dna polymerase iii
BKM78_10725	ENOG4105MA4	psp1 domain protein
BKM78_10750	ENOG4105I82	acetyl xylan esterase
BKM78_10755	ENOG4107QKS	N-acylglucosamine 2-epimerase
BKM78_10790	ENOG4105F0N	pyrophosphate phospho-hydrolase
BKM78_10805	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BKM78_10820	ENOG4105EUJ	GTP cyclohydrolase i
BKM78_10825	ENOG4105EEI	dihydropteroate synthase
BKM78_10835	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKM78_10850	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_10860	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BKM78_10865	ENOG4105JP4	Inner membrane protein yidG
BKM78_10870	ENOG4105VG5	Membrane
BKM78_10875	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
BKM78_10880	ENOG4108UCS	ABC, transporter
BKM78_10900	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BKM78_10915	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BKM78_10925	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
BKM78_10940	ENOG41083TI	Protein CrcB homolog
BKM78_10945	ENOG41082CG	Protein CrcB homolog
BKM78_10960	ENOG4105II7	pyrroline-5-carboxylate reductase
BKM78_10975	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BKM78_10980	ENOG4108RH7	phosphoglycerate mutase
BKM78_10985	ENOG4107QX9	Thiol disulfide interChange protein
BKM78_10990	ENOG4107QIV	Cytochrome c biogenesis protein
BKM78_10995	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
BKM78_11000	ENOG4105CRE	cytochrome C
BKM78_11010	ENOG4108W6C	Dehydrogenase
BKM78_11030	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BKM78_11045	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BKM78_11060	ENOG4105MP0	transposase
BKM78_11090	ENOG4105CMT	Dihydroxyacetone kinase
BKM78_11100	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
BKM78_11110	ENOG4105CMD	Transcriptional regulator, GntR family
BKM78_11115	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BKM78_11120	ENOG4108HHA	Transketolase
BKM78_11125	ENOG4108YZG	isomerase
BKM78_11130	ENOG4105DSU	hydrolase
BKM78_11160	ENOG4107NHD	transcriptional regulator
BKM78_11170	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BKM78_11175	ENOG4108SVG	May play a role in the intracellular transport of hydrophobic ligands
BKM78_11180	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BKM78_11215	ENOG4105CI3	gtp-binding protein typa
BKM78_11240	ENOG4105VDH	Dihydroxyacetone kinase
BKM78_11245	ENOG4108UTZ	Dihydroxyacetone kinase
BKM78_11250	ENOG4105CMT	Dihydroxyacetone kinase
BKM78_11255	ENOG4105K63	Thioredoxin
BKM78_11260	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BKM78_11265	ENOG4105C12	Phosphoribosylglycinamide synthetase
BKM78_11285	ENOG4105CHR	reductase
BKM78_11300	ENOG4105C83	adenylosuccinate lyase
BKM78_11320	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BKM78_11325	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BKM78_11345	ENOG4105C8V	SAICAR synthetase
BKM78_11355	ENOG4108VX5	3-methyladenine DNA glycosylase
BKM78_11360	ENOG4105CHM	Aminotransferase
BKM78_11375	ENOG410839H	phosphoribosylformylglycinamidine synthase
BKM78_11380	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
BKM78_11385	ENOG4105VC4	domain protein
BKM78_11395	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
BKM78_11400	ENOG4107QSE	Dipeptidase
BKM78_11410	ENOG4108KQ5	Integrase catalytic subunit
BKM78_11415	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
BKM78_11420	ENOG4108IJ0	Aspartate ammonia-lyase
BKM78_11425	ENOG4105CGU	Enoyl-CoA hydratase
BKM78_11435	ENOG4105IIU	Aminopeptidase
BKM78_11445	ENOG4105CG3	alpha amylase, catalytic region
BKM78_11460	ENOG4105D56	permease protein
BKM78_11465	ENOG4105EG2	ABC transporter, permease
BKM78_11475	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BKM78_11480	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BKM78_11490	ENOG4108IUE	nitrate reductase beta subunit
BKM78_11530	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BKM78_11535	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BKM78_11560	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BKM78_11580	ENOG4105NWF	RbsD or FucU transport
BKM78_11590	ENOG4105C2J	ABC transporter
BKM78_11595	ENOG4105CNN	ABC, transporter
BKM78_11600	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BKM78_11615	ENOG4105E9K	Isocitrate dehydrogenase
BKM78_11650	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BKM78_11660	ENOG4107QW3	Sucrose phosphorylase
BKM78_11675	ENOG4105TMB	Formate nitrite transporter
BKM78_11680	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BKM78_11685	ENOG4105F9U	Dehydrogenase
BKM78_11700	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BKM78_11710	ENOG4108UTZ	Dihydroxyacetone kinase
BKM78_11730	ENOG4107TCW	O-succinylbenzoate synthase
BKM78_11735	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
BKM78_11745	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BKM78_11765	ENOG4105E4F	Isochorismate synthase
BKM78_11770	ENOG4105P52	geranylgeranyl reductase
BKM78_11780	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11785	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BKM78_11790	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11800	ENOG4107QIZ	NADH dehydrogenase
BKM78_11805	ENOG4108IEH	NADH dehydrogenase subunit g
BKM78_11810	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BKM78_11815	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11820	ENOG4105DF2	NADH dehydrogenase subunit j
BKM78_11825	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11840	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11850	ENOG4105C9K	Endothelin-converting enzyme 1
BKM78_11855	ENOG4105DQU	oxidoreductase, subunit beta
BKM78_11860	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
BKM78_11865	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11870	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BKM78_11875	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BKM78_11880	ENOG41072RD	Membrane
BKM78_11890	ENOG4108VPT	UPF0234 protein
BKM78_11900	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
BKM78_11915	ENOG4105WDJ	50S ribosomal protein L33
BKM78_11920	ENOG410900P	UPF0336 protein
BKM78_11930	ENOG4107R4N	Cell wall formation (By similarity)
BKM78_11945	ENOG4105BZ1	(ABC) transporter
BKM78_11955	ENOG410683Z	Preprotein translocase SecE subunit
BKM78_11960	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BKM78_11965	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BKM78_11970	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BKM78_11975	ENOG4105E39	Enoyl-CoA hydratase
BKM78_11980	ENOG4105CVJ	phosphoglycerate mutase
BKM78_11985	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BKM78_12005	ENOG4105E5Q	amino acid AbC transporter
BKM78_12020	ENOG4108VZM	50s ribosomal protein L10
BKM78_12025	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BKM78_12030	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BKM78_12035	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BKM78_12040	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BKM78_12045	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BKM78_12050	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BKM78_12055	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BKM78_12060	ENOG4105CX6	glutaminyL-tRNA synthetase
BKM78_12070	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BKM78_12080	ENOG4105CHF	Glutathione S-transferase
BKM78_12090	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BKM78_12110	ENOG4105F1A	Pyruvate formate-lyase
BKM78_12115	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BKM78_12120	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BKM78_12125	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BKM78_12130	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BKM78_12135	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKM78_12140	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BKM78_12145	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BKM78_12150	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BKM78_12155	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BKM78_12160	ENOG41082SA	50s ribosomal protein l29
BKM78_12165	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BKM78_12175	ENOG4105E9Z	Nad-dependent epimerase dehydratase
BKM78_12180	ENOG4105C1J	atp-dependent rna helicase
BKM78_12185	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BKM78_12190	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BKM78_12195	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKM78_12200	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BKM78_12205	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BKM78_12210	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BKM78_12215	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BKM78_12220	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BKM78_12225	ENOG410849U	50S ribosomal protein L30
BKM78_12230	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BKM78_12235	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BKM78_12240	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BKM78_12270	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BKM78_12275	ENOG4108JP0	extracellular solute-binding protein family 1
BKM78_12285	ENOG4105F8D	glycoside hydrolase family 4
BKM78_12295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BKM78_12300	ENOG41067V7	50S ribosomal protein L36
BKM78_12305	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKM78_12310	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BKM78_12315	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BKM78_12320	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BKM78_12325	ENOG4108ZT0	50S ribosomal protein l17
BKM78_12340	ENOG4105C7J	ABC transporter, permease
BKM78_12345	ENOG4107T0D	ABC, transporter
BKM78_12360	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BKM78_12365	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BKM78_12370	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BKM78_12375	ENOG410901E	Membrane
BKM78_12395	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BKM78_12400	ENOG4108UJD	30S ribosomal protein S9
BKM78_12405	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BKM78_12415	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BKM78_12465	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BKM78_12470	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
BKM78_12475	ENOG4107XKF	NMT1 THI5 Like Domain Protein
BKM78_12480	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
BKM78_12490	ENOG4105C5F	glutamine synthetase
BKM78_12500	ENOG4105CIG	ABC transporter
BKM78_12505	ENOG4108ETY	sodium dicarboxylate symporter
BKM78_12520	ENOG4105C5H	ABC transporter
BKM78_12530	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BKM78_12540	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BKM78_12555	ENOG4105CGD	Nad-dependent epimerase dehydratase
BKM78_12560	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BKM78_12580	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BKM78_12585	ENOG4107X2D	transcriptional regulator, merr family
BKM78_12605	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BKM78_12645	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
BKM78_12650	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BKM78_12655	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
BKM78_12670	ENOG4105EUB	pirin domain protein
BKM78_12680	ENOG4107EUI	c reductase, iron-sulfur
BKM78_12690	ENOG4105CCU	oxidase (Subunit III)
BKM78_12705	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BKM78_12720	ENOG4105T0Z	Conserved Protein
BKM78_12725	ENOG4105KJF	protein tyrosine phosphatase
BKM78_12750	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
BKM78_12760	ENOG4105DA5	(ABC) transporter
BKM78_12795	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_12800	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BKM78_12825	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BKM78_12830	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BKM78_12845	ENOG4105EEM	helicase
BKM78_12860	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BKM78_12880	ENOG4105C0B	DNA polymerase III (alpha subunit)
BKM78_12885	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BKM78_12890	ENOG4108Z86	Glutamine amidotransferase
BKM78_12910	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BKM78_12915	ENOG4108V6E	Cell division protein mraZ
BKM78_12920	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BKM78_12930	ENOG4105CJN	penicillin-binding protein
BKM78_12945	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BKM78_12950	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BKM78_12955	ENOG4105CNI	cell division protein FtsW
BKM78_12960	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BKM78_12965	ENOG4105DFU	Cell wall formation (By similarity)
BKM78_12975	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BKM78_12980	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BKM78_13010	ENOG4105CA9	Pyruvate kinase
BKM78_13035	ENOG4105KA0	thioesterase Superfamily protein
BKM78_13050	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BKM78_13055	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BKM78_13060	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKM78_13065	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BKM78_13070	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BKM78_13080	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BKM78_13090	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BKM78_13095	ENOG4108QV3	biosynthesis protein
BKM78_13135	ENOG4105E2K	Glycosyl transferase (Group 1
BKM78_13140	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BKM78_13150	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BKM78_13155	ENOG4107ZYJ	bioY protein
BKM78_13160	ENOG4108JJB	ABC transporter
BKM78_13170	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BKM78_13180	ENOG4105CIE	May be required for sporulation (By similarity)
BKM78_13185	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BKM78_13190	ENOG4105BZA	Phosphoglycerate kinase
BKM78_13195	ENOG4105CP7	Triose-phosphate isomerase
BKM78_13210	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
BKM78_13225	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BKM78_13250	ENOG4105DGW	oligopeptidase A
BKM78_13255	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
BKM78_13285	ENOG4105VQD	rieske 2fe-2S domain-containing protein
BKM78_13290	ENOG4105C3K	feS assembly ATPase SufC
BKM78_13295	ENOG4105C9B	Cysteine desulfurase
BKM78_13300	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BKM78_13325	ENOG4105CJ1	ABC, transporter
BKM78_13340	ENOG4105WH1	Two component transcriptional regulator luxr family
BKM78_13355	ENOG4105C5H	ABC transporter
BKM78_13365	ENOG4105CG3	alpha amylase, catalytic region
BKM78_13370	ENOG4107RBJ	symporter
BKM78_13390	ENOG4105CHR	reductase
BKM78_13395	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
BKM78_13400	ENOG4105DKW	ABC transporter
BKM78_13420	ENOG4105DHU	Bile acid
BKM78_13430	ENOG4105FCS	tRNA rRNA methyltransferase
BKM78_13450	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BKM78_13455	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BKM78_13460	ENOG4105DR5	peptidase
BKM78_13465	ENOG4105CE9	30S ribosomal protein S2
BKM78_13470	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BKM78_13475	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BKM78_13480	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BKM78_13485	ENOG4105KNE	Phosphatidate cytidylyltransferase
BKM78_13490	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BKM78_13495	ENOG4107R37	Glutamate dehydrogenase
BKM78_13505	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BKM78_13510	ENOG4105DZP	Membrane-associated zinc metalloprotease
BKM78_13515	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BKM78_13525	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BKM78_13535	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
BKM78_13540	ENOG4105CHV	Transcription elongation factor NusA
BKM78_13550	ENOG4106839	domain protein
BKM78_13565	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BKM78_13570	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BKM78_13575	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BKM78_13590	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BKM78_13595	ENOG4105C26	Dehydrogenase
BKM78_13600	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BKM78_13605	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BKM78_13620	ENOG4105CN5	Metallo-Beta-Lactamase
BKM78_13625	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BKM78_13630	ENOG4105K46	50S ribosomal protein l27
BKM78_13635	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKM78_13640	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BKM78_13655	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BKM78_13660	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BKM78_13670	ENOG4105CVJ	phosphoglycerate mutase
BKM78_13685	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BKM78_13690	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BKM78_13695	ENOG4105C1Q	protoporphyrinogen oxidase
BKM78_13700	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BKM78_13710	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BKM78_13715	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BKM78_13730	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BKM78_13735	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
BKM78_13745	ENOG4105C6K	Malic enzyme
BKM78_13760	ENOG4107RWI	ethanolamine utilization protein eutJ
BKM78_13770	ENOG4105NDK	ethanolamine utilization protein
BKM78_13775	ENOG4105KNY	Microcompartments protein
BKM78_13780	ENOG4108EKI	Dehydrogenase
BKM78_13785	ENOG4106D67	ethanolamine utilization protein
BKM78_13790	ENOG4107FQ9	ethanolamine ammonia-lyase
BKM78_13795	ENOG4105CPD	ethanolamine ammonia-lyase
BKM78_13800	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
BKM78_13805	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BKM78_13810	ENOG4105ENY	Ethanolamine utilization protein eutH
BKM78_13825	ENOG4105C3U	ABC transporter
BKM78_13835	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BKM78_13840	ENOG4105DKQ	ROK family
BKM78_13845	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BKM78_13865	ENOG4105ECR	NmrA family
BKM78_13870	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BKM78_13875	ENOG4105DFW	ABC transporter
BKM78_13880	ENOG4105CNN	ABC, transporter
BKM78_13890	ENOG4105E2R	ROK family
BKM78_13895	ENOG4105C2J	ABC transporter
BKM78_13930	ENOG4105F0V	Cell wall hydrolase
BKM78_13950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BKM78_13955	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BKM78_13975	ENOG4105C8T	Leucyl-tRNA synthetase
BKM78_13980	ENOG4105KQC	Competence protein
BKM78_13995	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BKM78_14000	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BKM78_14005	ENOG4105C0A	alcohol dehydrogenase
BKM78_14020	ENOG4105ECY	inositol monophosphatase
BKM78_14025	ENOG4107T8T	UPF0173 metal-dependent hydrolase
BKM78_14030	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BKM78_14035	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BKM78_14045	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BKM78_14065	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BKM78_14080	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BKM78_14090	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
BKM78_14100	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BKM78_14115	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BKM78_14120	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
BKM78_14135	ENOG4105FDK	ABC transporter
BKM78_14140	ENOG4105DSE	periplasmic solute binding protein
BKM78_14145	ENOG4105EPJ	extracellular solute-binding protein family 1
BKM78_14150	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
BKM78_14155	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
BKM78_14170	ENOG4105E2R	ROK family
BKM78_14190	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BKM78_14205	ENOG4107QN1	sodium solute
BKM78_14255	ENOG4108EHY	type IV secretion system
BKM78_14315	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BKM78_14335	ENOG4105CPC	Aldo Keto reductase
BKM78_14340	ENOG4105ENX	hydrolase
BKM78_14355	ENOG4105C2C	drug resistance transporter, Bcr CflA
BKM78_14440	ENOG41085W3	Transposase
BKM78_14450	ENOG4107SCA	Formamidase (EC 3.5.1.49)
BKM78_14510	ENOG4108HKT	sucrose-6-phosphate hydrolase
BKM78_14515	ENOG4108HKT	sucrose-6-phosphate hydrolase
BKM78_14520	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BKM78_14525	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BKM78_14535	ENOG4105ETE	Transcriptional regulator (LacI family
BKM78_14540	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BKM78_14565	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BKM78_14580	ENOG4105C2X	Arabinose 5-phosphate isomerase
BKM78_14590	ENOG4105CNN	ABC, transporter
BKM78_14600	ENOG4105CNN	ABC, transporter
BKM78_14615	ENOG4105CPQ	Dehydrogenase
BKM78_14625	ENOG4105CMG	Carbohydrate kinase
BKM78_14635	ENOG4105DKT	Transcriptional regulator
BKM78_14645	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BKM78_14685	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
BKM78_14705	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BKM78_14715	ENOG4107QVM	von Willebrand factor, type A
BKM78_14720	ENOG4107QVM	von Willebrand factor, type A
BKM78_14725	ENOG4105DFA	alanine racemase domain protein
BKM78_14745	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BKM78_14770	ENOG4105BZG	amino acid carrier protein
BKM78_14775	ENOG4105DCG	PHP domain protein
BKM78_14780	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BKM78_14790	ENOG4105CTQ	phosphohexokinase