locus-tag	class	description
C7H83_00010	COG0589	response to stress
C7H83_00015	COG3344	reverse transcriptase
C7H83_00025	COG0561	phosphatase activity
C7H83_00030	COG0656	L-ascorbic acid biosynthetic process
C7H83_00040	COG0656	L-ascorbic acid biosynthetic process
C7H83_00045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7H83_00055	COG4473	ABC transporter
C7H83_00060	COG1131	(ABC) transporter
C7H83_00065	COG1132	(ABC) transporter
C7H83_00080	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7H83_00085	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7H83_00095	COG4149	molybdate abc transporter
C7H83_00110	COG0242	peptide deformylase activity
C7H83_00115	COG1464	Belongs to the NlpA lipoprotein family
C7H83_00120	COG2011	ABC-type metal ion transport system permease component
C7H83_00125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7H83_00130	COG0110	maltose O-acetyltransferase activity
C7H83_00145	COG0765	amino acid transport
C7H83_00150	COG1126	abc transporter atp-binding protein
C7H83_00155	COG1114	Component of the transport system for branched-chain amino acids
C7H83_00165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7H83_00170	COG2255	four-way junction helicase activity
C7H83_00180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7H83_00200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7H83_00205	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7H83_00210	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7H83_00215	COG1692	metallophosphoesterase
C7H83_00230	COG0561	phosphatase activity
C7H83_00240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7H83_00255	COG3279	Response regulator of the LytR AlgR family
C7H83_00265	COG1268	BioY protein
C7H83_00270	COG4493	Belongs to the UPF0637 family
C7H83_00295	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7H83_00295	COG2918	glutathione biosynthetic process
C7H83_00315	COG0552	protein localization to endoplasmic reticulum
C7H83_00320	COG0561	phosphatase activity
C7H83_00325	COG1196	nuclear chromosome segregation
C7H83_00330	COG0571	ribonuclease III activity
C7H83_00335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7H83_00340	COG0416	fatty acid biosynthetic process
C7H83_00345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7H83_00350	COG1461	Dihydroxyacetone kinase
C7H83_00360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7H83_00380	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7H83_00420	COG4485	Bacterial membrane protein, YfhO
C7H83_00425	COG0174	glutamine synthetase
C7H83_00430	COG3344	reverse transcriptase
C7H83_00435	COG0101	tRNA pseudouridine synthase activity
C7H83_00445	COG1122	ATPase activity
C7H83_00450	COG1122	ATPase activity
C7H83_00455	COG0203	ribosomal protein L17
C7H83_00460	COG0202	RNA polymerase activity
C7H83_00465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7H83_00470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7H83_00475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7H83_00480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7H83_00485	COG0563	adenylate kinase activity
C7H83_00490	COG0201	protein transport
C7H83_00495	COG0200	Binds to the 23S rRNA
C7H83_00500	COG1841	ribosomal large subunit assembly
C7H83_00505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7H83_00510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7H83_00515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7H83_00520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7H83_00525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7H83_00530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7H83_00535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7H83_00540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7H83_00545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7H83_00550	COG0255	Belongs to the universal ribosomal protein uL29 family
C7H83_00560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7H83_00565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7H83_00570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7H83_00575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7H83_00580	COG0089	rRNA binding
C7H83_00585	COG0088	Forms part of the polypeptide exit tunnel
C7H83_00590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7H83_00595	COG0051	transcription antitermination factor activity, RNA binding
C7H83_00610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7H83_00615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7H83_00620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7H83_00625	COG0049	tRNA binding
C7H83_00630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7H83_00635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7H83_00640	COG0588	phosphoglycerate mutase activity
C7H83_00645	COG1979	alcohol dehydrogenase
C7H83_00680	COG1744	ABC transporter substrate-binding protein PnrA-like
C7H83_00685	COG0295	cytidine deaminase activity
C7H83_00690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7H83_00705	COG2813	Specifically methylates the guanine in position
C7H83_00710	COG1072	(Pantothenic acid kinase))
C7H83_00715	COG0519	Catalyzes the synthesis of GMP from XMP
C7H83_00715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7H83_00720	COG3344	reverse transcriptase
C7H83_00745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7H83_00780	COG1396	sequence-specific DNA binding
C7H83_00815	COG3328	transposase activity
C7H83_00845	COG1104	cysteine desulfurase activity
C7H83_00850	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C7H83_00855	COG0709	Synthesizes selenophosphate from selenide and ATP
C7H83_00865	COG0640	Transcriptional regulator
C7H83_00870	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7H83_00875	COG0708	Exodeoxyribonuclease III
C7H83_00880	COG0628	permease
C7H83_00900	COG0561	phosphatase activity
C7H83_00910	COG1126	abc transporter atp-binding protein
C7H83_00935	COG2197	response regulator
C7H83_00940	COG4585	Histidine kinase
C7H83_00945	COG1968	undecaprenyl-diphosphatase activity
C7H83_00950	COG1388	LysM domain
C7H83_00965	COG2340	Cysteine-rich secretory protein family
C7H83_00970	COG1305	Transglutaminase-like
C7H83_00980	COG0714	Associated with various cellular activities
C7H83_00985	COG0435	Glutathione S-transferase
C7H83_00995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7H83_01000	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7H83_01025	COG1136	(ABC) transporter
C7H83_01025	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7H83_01030	COG1309	transcriptional regulator
C7H83_01055	COG0574	Belongs to the PEP-utilizing enzyme family
C7H83_01055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7H83_01060	COG0517	IMP dehydrogenase activity
C7H83_01065	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7H83_01070	COG0039	L-malate dehydrogenase activity
C7H83_01075	COG1737	Transcriptional regulator
C7H83_01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7H83_01090	COG1263	PTS System
C7H83_01090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7H83_01110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7H83_01260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7H83_01265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7H83_01280	COG0037	tRNA processing
C7H83_01285	COG1098	S1 RNA binding domain
C7H83_01295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7H83_01300	COG2244	polysaccharide biosynthetic process
C7H83_01305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7H83_01310	COG0193	aminoacyl-tRNA hydrolase activity
C7H83_01315	COG0039	L-malate dehydrogenase activity
C7H83_01325	COG0217	transcriptional regulatory protein
C7H83_01335	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_01345	COG2814	Major facilitator Superfamily
C7H83_01380	COG4166	transmembrane transport
C7H83_01390	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7H83_01390	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7H83_01400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7H83_01405	COG4988	ABC transporter
C7H83_01410	COG1294	oxidase, subunit
C7H83_01415	COG1271	oxidase subunit
C7H83_01430	COG4975	Glucose uptake
C7H83_01440	COG0018	arginyl-trna synthetase
C7H83_01450	COG2235	arginine
C7H83_01455	COG1438	arginine binding
C7H83_01460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_01460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_01465	COG2723	6-phospho-beta-galactosidase activity
C7H83_01470	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7H83_01475	COG3684	Belongs to the aldolase LacD family
C7H83_01510	COG1349	DNA-binding transcription factor activity
C7H83_01525	COG2267	carboxylic ester hydrolase activity
C7H83_01530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7H83_01535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7H83_01540	COG0783	Belongs to the Dps family
C7H83_01570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7H83_01575	COG1162	GTPase activity
C7H83_01650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7H83_01665	COG0012	GTP binding
C7H83_01670	COG4481	Protein conserved in bacteria
C7H83_01675	COG1475	DNA binding
C7H83_01680	COG1192	Involved in chromosome partitioning
C7H83_01685	COG0357	Ribosomal RNA small subunit methyltransferase G
C7H83_01710	COG1442	glycosyl transferase family 8
C7H83_01740	COG1304	FMN binding
C7H83_01750	COG1380	Effector of murein hydrolase LrgA
C7H83_01775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7H83_01780	COG0445	tRNA wobble uridine modification
C7H83_01785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7H83_01800	COG0706	membrane insertase activity
C7H83_01805	COG0594	ribonuclease P activity
C7H83_01810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7H83_01820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7H83_01825	COG0592	DNA-directed DNA polymerase activity
C7H83_01830	COG2501	S4 domain
C7H83_01835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7H83_01840	COG0187	DNA topoisomerase II activity
C7H83_01850	COG0360	Binds together with S18 to 16S ribosomal RNA
C7H83_01860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7H83_01870	COG0359	binds to the 23S rRNA
C7H83_01875	COG0305	Participates in initiation and elongation during chromosome replication
C7H83_01880	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7H83_01885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7H83_01895	COG0488	(ABC) transporter
C7H83_01910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7H83_01915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7H83_01925	COG3949	Membrane
C7H83_01930	COG0656	L-ascorbic acid biosynthetic process
C7H83_01935	COG0756	dUTP diphosphatase activity
C7H83_01945	COG4956	integral membrane protein (PIN domain superfamily)
C7H83_01950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7H83_01955	COG0215	cysteine-tRNA ligase activity
C7H83_01960	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7H83_01965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7H83_01970	COG3688	RNA-binding protein containing a PIN domain
C7H83_01980	COG4466	Protein conserved in bacteria
C7H83_01985	COG1970	mechanosensitive ion channel activity
C7H83_01990	COG0612	Peptidase, M16
C7H83_01995	COG0612	Peptidase, M16
C7H83_02000	COG1426	Protein conserved in bacteria
C7H83_02005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7H83_02010	COG1546	Belongs to the CinA family
C7H83_02010	COG1058	Belongs to the CinA family
C7H83_02015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7H83_02020	COG1418	mRNA catabolic process
C7H83_02025	COG2188	Transcriptional regulator
C7H83_02030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7H83_02035	COG1554	hydrolase, family 65, central catalytic
C7H83_02040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_02040	COG1263	PTS System
C7H83_02045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7H83_02050	COG1121	(ABC) transporter
C7H83_02055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7H83_02060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7H83_02065	COG0105	UTP biosynthetic process
C7H83_02070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7H83_02075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7H83_02090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7H83_02100	COG0351	phosphomethylpyrimidine kinase
C7H83_02115	COG4443	Transcriptional Coactivator p15 (PC4)
C7H83_02120	COG0194	GDP metabolic process
C7H83_02125	COG1758	RNA polymerase activity
C7H83_02130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7H83_02135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7H83_02140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7H83_02140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7H83_02150	COG0515	serine threonine protein kinase
C7H83_02150	COG2815	serine threonine protein kinase
C7H83_02155	COG4463	regulation of RNA biosynthetic process
C7H83_02160	COG0542	response to heat
C7H83_02180	COG0456	acetyltransferase
C7H83_02185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7H83_02190	COG0142	geranyltranstransferase activity
C7H83_02205	COG4939	FMN-binding domain protein
C7H83_02230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7H83_02235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_02240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_02245	COG0745	RESPONSE REGULATOR receiver
C7H83_02260	COG2205	protein histidine kinase activity
C7H83_02270	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_02275	COG1464	Belongs to the NlpA lipoprotein family
C7H83_02280	COG0488	(ABC) transporter
C7H83_02290	COG0693	protein deglycase activity
C7H83_02295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7H83_02300	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_02305	COG3775	system Galactitol-specific IIC component
C7H83_02325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7H83_02330	COG0671	phosphoesterase, PA-phosphatase related
C7H83_02335	COG1388	LysM domain
C7H83_02335	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7H83_02345	COG0495	leucyl-tRNA aminoacylation
C7H83_02350	COG1764	response to oxidative stress
C7H83_02360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7H83_02365	COG2244	polysaccharide biosynthetic process
C7H83_02370	COG1187	pseudouridine synthase activity
C7H83_02375	COG0564	pseudouridine synthase activity
C7H83_02380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7H83_02385	COG3679	Belongs to the UPF0342 family
C7H83_02390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7H83_02410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7H83_02415	COG0746	molybdenum cofactor guanylyltransferase activity
C7H83_02420	COG2116	formate transmembrane transporter activity
C7H83_02440	COG3383	formate dehydrogenase (NAD+) activity
C7H83_02470	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7H83_02475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7H83_02485	COG0537	adenosine 5'-monophosphoramidase activity
C7H83_02500	COG1482	cell wall glycoprotein biosynthetic process
C7H83_02515	COG3442	glutamine amidotransferase
C7H83_02520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7H83_02525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7H83_02530	COG0681	Belongs to the peptidase S26 family
C7H83_02535	COG0514	ATP-dependent DNA helicase (RecQ)
C7H83_02540	COG0071	Belongs to the small heat shock protein (HSP20) family
C7H83_02555	COG1435	thymidine kinase activity
C7H83_02560	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7H83_02565	COG2890	protein-(glutamine-N5) methyltransferase activity
C7H83_02570	COG0009	L-threonylcarbamoyladenylate synthase
C7H83_02575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7H83_02580	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7H83_02595	COG0772	Belongs to the SEDS family
C7H83_02610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7H83_02615	COG0572	uridine kinase
C7H83_02630	COG1671	Belongs to the UPF0178 family
C7H83_02635	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7H83_02640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7H83_02650	COG0736	holo-[acyl-carrier-protein] synthase activity
C7H83_02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7H83_02660	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7H83_02670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7H83_02695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7H83_02705	COG0343	queuine tRNA-ribosyltransferase activity
C7H83_02715	COG1304	FMN binding
C7H83_02730	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7H83_02740	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_02745	COG0402	S-adenosylhomocysteine deaminase activity
C7H83_02750	COG0402	S-adenosylhomocysteine deaminase activity
C7H83_02755	COG2508	Transcriptional regulator
C7H83_02760	COG4166	transmembrane transport
C7H83_02765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7H83_02770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7H83_02775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7H83_02790	COG0824	Thioesterase
C7H83_02795	COG0124	histidyl-tRNA synthetase
C7H83_02800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7H83_02805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7H83_02810	COG2755	lipolytic protein G-D-S-L family
C7H83_02810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7H83_02815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7H83_02820	COG1459	type II secretion system
C7H83_02825	COG4537	Required for transformation and DNA binding
C7H83_02855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7H83_02860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7H83_02880	COG1363	Peptidase, m42
C7H83_02885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7H83_02890	COG0589	response to stress
C7H83_02895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7H83_02905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7H83_02910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7H83_02915	COG3711	transcriptional antiterminator
C7H83_02930	COG0322	excinuclease ABC activity
C7H83_02955	COG0492	ferredoxin-NADP+ reductase activity
C7H83_02960	COG1846	Transcriptional regulator
C7H83_02965	COG0386	Belongs to the glutathione peroxidase family
C7H83_02970	COG3118	belongs to the thioredoxin family
C7H83_02980	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7H83_02985	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_02995	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7H83_03000	COG2376	Dihydroxyacetone kinase
C7H83_03005	COG1461	Dihydroxyacetone kinase
C7H83_03030	COG2188	Transcriptional regulator
C7H83_03035	COG2222	sugar isomerase
C7H83_03045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7H83_03055	COG0702	epimerase
C7H83_03065	COG2217	Heavy metal translocating P-type atpase
C7H83_03070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7H83_03070	COG0425	Belongs to the sulfur carrier protein TusA family
C7H83_03075	COG1285	pathogenesis
C7H83_03090	COG1269	ATP hydrolysis coupled proton transport
C7H83_03095	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7H83_03105	COG1527	subunit (C
C7H83_03115	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
C7H83_03120	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
C7H83_03125	COG1394	ATPase activity, coupled to movement of substances
C7H83_03130	COG1073	alpha beta
C7H83_03165	COG1940	carbohydrate kinase activity
C7H83_03175	COG1695	Transcriptional regulator
C7H83_03180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7H83_03185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7H83_03200	COG3328	transposase activity
C7H83_03210	COG0577	efflux transmembrane transporter activity
C7H83_03210	COG1136	(ABC) transporter
C7H83_03210	COG0577	efflux transmembrane transporter activity
C7H83_03210	COG1136	(ABC) transporter
C7H83_03220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7H83_03240	COG0367	asparagine synthase
C7H83_03265	COG3344	reverse transcriptase
C7H83_03290	COG2188	Transcriptional regulator
C7H83_03295	COG4175	Glycine betaine
C7H83_03295	COG3448	diguanylate cyclase activity
C7H83_03320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7H83_03325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7H83_03330	COG0471	metal ion transport
C7H83_03340	COG1943	Transposase
C7H83_03350	COG0363	glucosamine-6-phosphate deaminase activity
C7H83_03355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7H83_03360	COG4109	DRTGG domain
C7H83_03365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7H83_03380	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_03395	COG0531	amino acid
C7H83_03400	COG1082	Xylose isomerase domain protein TIM barrel
C7H83_03405	COG1053	succinate dehydrogenase
C7H83_03435	COG1408	metallophosphoesterase
C7H83_03440	COG0084	hydrolase, TatD family'
C7H83_03445	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7H83_03450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7H83_03465	COG3385	transposase activity
C7H83_03480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7H83_03485	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7H83_03490	COG1472	Belongs to the glycosyl hydrolase 3 family
C7H83_03515	COG3448	diguanylate cyclase activity
C7H83_03515	COG4175	Glycine betaine
C7H83_03525	COG5039	Polysaccharide pyruvyl transferase
C7H83_03530	COG5039	Polysaccharide pyruvyl transferase
C7H83_03535	COG2261	transglycosylase associated protein
C7H83_03545	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7H83_03560	COG0716	FMN binding
C7H83_03565	COG0628	permease
C7H83_03570	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7H83_03570	COG3942	CHAP domain
C7H83_03585	COG1316	TRANSCRIPTIONal
C7H83_03595	COG0489	protein tyrosine kinase activity
C7H83_03600	COG4464	protein tyrosine phosphatase activity
C7H83_03610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7H83_03635	COG1216	Glycosyl transferase, family 2
C7H83_03635	COG0463	Glycosyl transferase, family 2
C7H83_03640	COG0438	transferase activity, transferring glycosyl groups
C7H83_03715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_03725	COG2723	6-phospho-beta-galactosidase activity
C7H83_03730	COG1105	Belongs to the carbohydrate kinase PfkB family
C7H83_03735	COG1349	DNA-binding transcription factor activity
C7H83_03745	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_03810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7H83_03825	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_03830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7H83_03835	COG1937	Protein conserved in bacteria
C7H83_03840	COG3316	Transposase and inactivated derivatives
C7H83_03985	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_03990	COG3775	system Galactitol-specific IIC component
C7H83_04010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_04020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_04025	COG2723	6-phospho-beta-galactosidase activity
C7H83_04030	COG0300	oxidoreductase activity
C7H83_04055	COG0662	Cupin 2, conserved barrel domain protein
C7H83_04060	COG4619	ABC transporter
C7H83_04065	COG0390	transport system, permease component
C7H83_04080	COG0783	Belongs to the Dps family
C7H83_04085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_04095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_04145	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C7H83_04150	COG0783	Belongs to the Dps family
C7H83_04155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_04160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_04165	COG3316	Transposase and inactivated derivatives
C7H83_04215	COG3316	Transposase and inactivated derivatives
C7H83_04240	COG0582	viral genome integration into host DNA
C7H83_04275	COG2050	protein possibly involved in aromatic compounds catabolism
C7H83_04280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7H83_04285	COG0318	PFAM AMP-dependent synthetase and ligase
C7H83_04305	COG2113	Glycine betaine
C7H83_04310	COG1510	regulation of RNA biosynthetic process
C7H83_04320	COG1454	alcohol dehydrogenase
C7H83_04350	COG2814	Major facilitator Superfamily
C7H83_04365	COG4975	Glucose uptake
C7H83_04370	COG1869	D-ribose catabolic process
C7H83_04380	COG2017	converts alpha-aldose to the beta-anomer
C7H83_04385	COG2814	Major facilitator Superfamily
C7H83_04405	COG2723	6-phospho-beta-galactosidase activity
C7H83_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_04410	COG2190	(PTS) system
C7H83_04410	COG1263	PTS System
C7H83_04415	COG2188	Transcriptional regulator
C7H83_04440	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7H83_04445	COG2376	Dihydroxyacetone kinase
C7H83_04450	COG1461	Dihydroxyacetone kinase
C7H83_04460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7H83_04465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7H83_04475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7H83_04480	COG2252	PERMEase
C7H83_04485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7H83_04500	COG1263	PTS System
C7H83_04500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_04515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7H83_04535	COG1744	ABC transporter substrate-binding protein PnrA-like
C7H83_04560	COG4989	oxidoreductase activity
C7H83_04565	COG3284	Transcriptional regulator
C7H83_04570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7H83_04580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7H83_04585	COG0022	dehydrogenase e1 component
C7H83_04590	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7H83_04600	COG2217	Heavy metal translocating P-type atpase
C7H83_04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_04610	COG1263	PTS System
C7H83_04615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7H83_04620	COG1737	Transcriptional regulator
C7H83_04630	COG0383	alpha-mannosidase activity
C7H83_04660	COG0738	Major facilitator superfamily
C7H83_04670	COG1609	Transcriptional regulator
C7H83_04685	COG3069	C4-dicarboxylate transmembrane transporter activity
C7H83_04705	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7H83_04730	COG0549	Belongs to the carbamate kinase family
C7H83_04745	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7H83_04750	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7H83_04755	COG2390	Transcriptional regulator
C7H83_04760	COG0657	acetylesterase activity
C7H83_04760	COG2755	lipolytic protein G-D-S-L family
C7H83_04780	COG2271	Major facilitator Superfamily
C7H83_04790	COG4297	protein containing double-stranded beta helix domain
C7H83_04795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7H83_04815	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_04815	COG1454	alcohol dehydrogenase
C7H83_04820	COG1063	alcohol dehydrogenase
C7H83_04825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7H83_04830	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7H83_04835	COG2376	Dihydroxyacetone kinase
C7H83_04840	COG1461	Dihydroxyacetone kinase
C7H83_04850	COG1349	DNA-binding transcription factor activity
C7H83_04860	COG0698	ribose 5-phosphate isomerase
C7H83_04870	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_04885	COG0800	Aldolase
C7H83_04890	COG2610	gluconate transmembrane transporter activity
C7H83_04895	COG2186	Transcriptional regulator
C7H83_04905	COG1737	Transcriptional regulator
C7H83_04910	COG1486	melibiose metabolic process
C7H83_04915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_04915	COG1263	PTS System
C7H83_04920	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C7H83_04930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_04930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_04935	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7H83_04945	COG3711	transcriptional antiterminator
C7H83_04945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_04955	COG3730	PTS system glucitol sorbitol-specific
C7H83_04965	COG3732	PTS system glucitol sorbitol-specific
C7H83_04980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7H83_04985	COG2233	PERMEase
C7H83_04995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7H83_05000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7H83_05005	COG1120	ATPase activity
C7H83_05010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7H83_05015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7H83_05020	COG0477	Major facilitator Superfamily
C7H83_05025	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7H83_05030	COG0492	ferredoxin-NADP+ reductase activity
C7H83_05040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7H83_05045	COG1098	S1 RNA binding domain
C7H83_05130	COG0783	Belongs to the Dps family
C7H83_05135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_05150	COG2217	Heavy metal translocating P-type atpase
C7H83_05160	COG0693	protein deglycase activity
C7H83_05175	COG0640	Transcriptional regulator
C7H83_05185	COG1917	Cupin 2, conserved barrel domain protein
C7H83_05185	COG2207	Transcriptional regulator
C7H83_05215	COG2826	transposase and inactivated derivatives, IS30 family
C7H83_05235	COG0667	Aldo Keto reductase
C7H83_05245	COG1979	alcohol dehydrogenase
C7H83_05265	COG0789	Transcriptional regulator
C7H83_05275	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_05290	COG4221	oxidoreductase activity
C7H83_05295	COG0789	Transcriptional regulator
C7H83_05305	COG3328	transposase activity
C7H83_05315	COG0656	L-ascorbic acid biosynthetic process
C7H83_05320	COG0789	Transcriptional regulator
C7H83_05360	COG0798	PFAM Bile acid sodium symporter
C7H83_05380	COG5002	protein histidine kinase activity
C7H83_05385	COG0745	RESPONSE REGULATOR receiver
C7H83_05410	COG1309	transcriptional regulator
C7H83_05425	COG0640	Transcriptional regulator
C7H83_05450	COG3385	transposase activity
C7H83_05455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7H83_05465	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7H83_05475	COG0411	ABC transporter
C7H83_05480	COG0410	ABC transporter
C7H83_05485	COG0517	IMP dehydrogenase activity
C7H83_05485	COG0516	GMP reductase activity
C7H83_05495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7H83_05500	COG1902	pentaerythritol trinitrate reductase activity
C7H83_05515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7H83_05525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7H83_05560	COG3594	Acyltransferase
C7H83_05565	COG3579	cysteine-type endopeptidase activity
C7H83_05580	COG2814	Major facilitator Superfamily
C7H83_05590	COG1823	symporter activity
C7H83_05605	COG1801	Protein of unknown function DUF72
C7H83_05610	COG0561	phosphatase activity
C7H83_05620	COG4876	unkown
C7H83_05625	COG4166	transmembrane transport
C7H83_05635	COG0527	aspartate kinase activity
C7H83_05640	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7H83_05645	COG1104	cysteine desulfurase activity
C7H83_05650	COG0301	tRNA thio-modification
C7H83_05655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7H83_05660	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7H83_05670	COG0525	valine-tRNA ligase activity
C7H83_05675	COG0285	dihydrofolate synthase activity
C7H83_05680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7H83_05685	COG2003	Belongs to the UPF0758 family
C7H83_05690	COG1278	Cold shock
C7H83_05715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7H83_05720	COG0745	RESPONSE REGULATOR receiver
C7H83_05725	COG3850	Histidine kinase
C7H83_05725	COG5002	protein histidine kinase activity
C7H83_05740	COG0740	serine-type endopeptidase activity
C7H83_05750	COG0584	glycerophosphoryl diester phosphodiesterase
C7H83_05755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7H83_05765	COG0789	Transcriptional regulator
C7H83_05775	COG0504	CTP synthase activity
C7H83_05785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7H83_05790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7H83_05795	COG0254	rRNA binding
C7H83_05820	COG2390	Transcriptional regulator
C7H83_05845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7H83_05875	COG0745	RESPONSE REGULATOR receiver
C7H83_05880	COG5002	protein histidine kinase activity
C7H83_05900	COG1136	(ABC) transporter
C7H83_05920	COG1725	Transcriptional regulator
C7H83_05925	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7H83_05930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7H83_05935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7H83_05940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7H83_05945	COG0131	Imidazoleglycerol-phosphate dehydratase
C7H83_05950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7H83_05955	COG0107	imidazoleglycerol-phosphate synthase activity
C7H83_05960	COG0140	phosphoribosyl-ATP diphosphatase activity
C7H83_05960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7H83_05975	COG3339	Conserved Protein
C7H83_05990	COG0352	thiamine-phosphate diphosphorylase activity
C7H83_05995	COG0351	phosphomethylpyrimidine kinase
C7H83_06020	COG1473	amidohydrolase
C7H83_06025	COG1473	amidohydrolase
C7H83_06030	COG0601	transmembrane transport
C7H83_06035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7H83_06045	COG0444	Belongs to the ABC transporter superfamily
C7H83_06050	COG4608	Belongs to the ABC transporter superfamily
C7H83_06060	COG1733	regulation of RNA biosynthetic process
C7H83_06065	COG1902	pentaerythritol trinitrate reductase activity
C7H83_06080	COG2130	NADP-dependent
C7H83_06090	COG1464	Belongs to the NlpA lipoprotein family
C7H83_06095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7H83_06110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_06115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7H83_06120	COG2169	Transcriptional regulator
C7H83_06125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7H83_06135	COG0431	NADPH-dependent FMN reductase
C7H83_06145	COG3344	reverse transcriptase
C7H83_06150	COG0367	asparagine synthase
C7H83_06165	COG1595	DNA-templated transcription, initiation
C7H83_06175	COG1131	(ABC) transporter
C7H83_06205	COG3620	sequence-specific DNA binding
C7H83_06220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7H83_06225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7H83_06245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7H83_06260	COG3344	reverse transcriptase
C7H83_06275	COG1063	alcohol dehydrogenase
C7H83_06280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7H83_06285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_06285	COG3711	transcriptional antiterminator
C7H83_06290	COG2723	6-phospho-beta-galactosidase activity
C7H83_06300	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7H83_06310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_06325	COG0561	phosphatase activity
C7H83_06355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7H83_06365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7H83_06370	COG0069	glutamate synthase activity
C7H83_06370	COG0067	glutamate synthase
C7H83_06370	COG0070	glutamate synthase
C7H83_06375	COG0493	'glutamate synthase
C7H83_06385	COG2826	transposase and inactivated derivatives, IS30 family
C7H83_06390	COG0004	ammonium transporteR
C7H83_06400	COG0583	DNA-binding transcription factor activity
C7H83_06425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7H83_06435	COG0789	Transcriptional regulator
C7H83_06440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7H83_06445	COG0531	amino acid
C7H83_06455	COG3328	transposase activity
C7H83_06465	COG0745	RESPONSE REGULATOR receiver
C7H83_06470	COG5002	protein histidine kinase activity
C7H83_06485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7H83_06515	COG2188	Transcriptional regulator
C7H83_06520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_06525	COG2723	6-phospho-beta-galactosidase activity
C7H83_06530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7H83_06535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7H83_06540	COG1368	sulfuric ester hydrolase activity
C7H83_06545	COG0583	DNA-binding transcription factor activity
C7H83_06550	COG1780	Probably involved in ribonucleotide reductase function
C7H83_06565	COG0561	phosphatase activity
C7H83_06570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7H83_06575	COG0280	phosphate acetyltransferase
C7H83_06580	COG0802	atpase or kinase
C7H83_06605	COG2723	6-phospho-beta-galactosidase activity
C7H83_06625	COG3711	transcriptional antiterminator
C7H83_06630	COG1609	Transcriptional regulator
C7H83_06635	COG1263	PTS System
C7H83_06635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_06645	COG1621	beta-fructofuranosidase activity
C7H83_06665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7H83_06710	COG1403	HNH endonuclease
C7H83_06720	COG1783	phage Terminase large subunit
C7H83_06835	COG0582	viral genome integration into host DNA
C7H83_06860	COG1396	sequence-specific DNA binding
C7H83_06935	COG2610	gluconate transmembrane transporter activity
C7H83_06955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_06960	COG1609	Transcriptional regulator
C7H83_06970	COG2723	6-phospho-beta-galactosidase activity
C7H83_06990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_06995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7H83_07010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7H83_07040	COG4975	Glucose uptake
C7H83_07050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7H83_07095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_07100	COG0583	DNA-binding transcription factor activity
C7H83_07130	COG1129	ABC transporter
C7H83_07150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_07155	COG0277	FAD linked oxidase domain protein
C7H83_07185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7H83_07190	COG0366	Alpha amylase catalytic
C7H83_07220	COG3711	transcriptional antiterminator
C7H83_07240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7H83_07255	COG3715	PTS system
C7H83_07285	COG0673	inositol 2-dehydrogenase activity
C7H83_07305	COG1653	transport
C7H83_07310	COG1175	transmembrane transport
C7H83_07320	COG2190	(PTS) system
C7H83_07320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_07320	COG1263	PTS System
C7H83_07330	COG1394	ATPase activity, coupled to movement of substances
C7H83_07335	COG4166	transmembrane transport
C7H83_07350	COG2723	6-phospho-beta-galactosidase activity
C7H83_07355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_07370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_07370	COG1263	PTS System
C7H83_07375	COG1486	melibiose metabolic process
C7H83_07380	COG1737	Transcriptional regulator
C7H83_07390	COG0165	Argininosuccinate lyase
C7H83_07405	COG2096	Adenosyltransferase
C7H83_07410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7H83_07435	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7H83_07440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7H83_07445	COG1534	Rna-binding protein
C7H83_07450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7H83_07455	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7H83_07460	COG0799	negative regulation of ribosome biogenesis
C7H83_07465	COG2226	methyltransferase
C7H83_07470	COG1323	Belongs to the UPF0348 family
C7H83_07475	COG0217	transcriptional regulatory protein
C7H83_07490	COG0569	domain protein
C7H83_07490	COG0475	glutathione-regulated potassium exporter activity
C7H83_07540	COG3189	MarR family transcriptional regulator
C7H83_07555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7H83_07560	COG0779	Required for maturation of 30S ribosomal subunits
C7H83_07565	COG0195	Participates in both transcription termination and antitermination
C7H83_07570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7H83_07585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7H83_07590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7H83_07595	COG0196	riboflavin kinase activity
C7H83_07615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7H83_07640	COG1126	abc transporter atp-binding protein
C7H83_07645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_07650	COG0556	nucleotide-excision repair
C7H83_07655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7H83_07660	COG1660	Displays ATPase and GTPase activities
C7H83_07665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7H83_07670	COG1481	regulation of sporulation
C7H83_07680	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7H83_07690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7H83_07710	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7H83_07715	COG1074	ATP-dependent DNA helicase activity
C7H83_07720	COG1733	regulation of RNA biosynthetic process
C7H83_07725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7H83_07730	COG0072	phenylalanine-tRNA ligase activity
C7H83_07730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_07735	COG0180	Tryptophanyl-tRNA synthetase
C7H83_07740	COG1126	abc transporter atp-binding protein
C7H83_07745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_07750	COG0765	amino acid transport
C7H83_07755	COG0765	amino acid transport
C7H83_07760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7H83_07775	COG0517	IMP dehydrogenase activity
C7H83_07780	COG0668	transmembrane transport
C7H83_07785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7H83_07790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7H83_07810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7H83_07820	COG1234	tRNA 3'-trailer cleavage
C7H83_07825	COG0300	oxidoreductase activity
C7H83_07830	COG5416	Lipopolysaccharide assembly protein A domain
C7H83_07835	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7H83_07835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7H83_07840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7H83_07865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7H83_07870	COG4224	UPF0291 protein
C7H83_07880	COG1388	LysM domain
C7H83_07880	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7H83_07885	COG0735	belongs to the Fur family
C7H83_07890	COG3935	DnaD domain protein
C7H83_07895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7H83_07900	COG3331	DNA recombination
C7H83_07905	COG4474	Belongs to the UPF0398 family
C7H83_07910	COG3599	regulation of cell shape
C7H83_07920	COG0116	Belongs to the methyltransferase superfamily
C7H83_07960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7H83_07965	COG2832	Protein of unknown function (DUF454)
C7H83_07975	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_07990	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7H83_07995	COG1418	mRNA catabolic process
C7H83_08005	COG0513	Belongs to the DEAD box helicase family
C7H83_08020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7H83_08035	COG0328	RNA-DNA hybrid ribonuclease activity
C7H83_08045	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7H83_08055	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7H83_08060	COG0564	pseudouridine synthase activity
C7H83_08065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7H83_08080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7H83_08085	COG0505	Belongs to the CarA family
C7H83_08090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7H83_08095	COG0284	orotidine-5'-phosphate decarboxylase activity
C7H83_08100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7H83_08125	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7H83_08135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7H83_08140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7H83_08145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7H83_08150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7H83_08155	COG0287	Prephenate dehydrogenase
C7H83_08165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7H83_08170	COG0077	Prephenate dehydratase
C7H83_08175	COG1316	TRANSCRIPTIONal
C7H83_08180	COG1307	EDD domain protein, DegV family
C7H83_08185	COG2124	cytochrome p450
C7H83_08205	COG0456	acetyltransferase
C7H83_08210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7H83_08220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7H83_08225	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_08230	COG0753	catalase activity
C7H83_08235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7H83_08245	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_08250	COG1388	LysM domain
C7H83_08265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7H83_08280	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_08315	COG2151	metal-sulfur cluster biosynthetic enzyme
C7H83_08320	COG1199	ATP-dependent helicase activity
C7H83_08325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7H83_08335	COG1968	undecaprenyl-diphosphatase activity
C7H83_08340	COG1392	Phosphate transport regulator
C7H83_08345	COG0306	phosphate transporter
C7H83_08350	COG0268	Binds directly to 16S ribosomal RNA
C7H83_08355	COG1466	dna polymerase III delta subunit
C7H83_08360	COG2333	competence protein COMEC
C7H83_08360	COG0658	competence protein
C7H83_08365	COG2131	deaminase
C7H83_08370	COG1596	polysaccharide export
C7H83_08370	COG1555	photosystem II stabilization
C7H83_08380	COG0436	Aminotransferase
C7H83_08385	COG1126	abc transporter atp-binding protein
C7H83_08390	COG0765	amino acid transport
C7H83_08395	COG0519	Catalyzes the synthesis of GMP from XMP
C7H83_08405	COG0702	epimerase
C7H83_08410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7H83_08420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7H83_08425	COG0154	amidase activity
C7H83_08430	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7H83_08435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7H83_08440	COG0210	DNA helicase
C7H83_08445	COG0038	chloride channel
C7H83_08450	COG1349	DNA-binding transcription factor activity
C7H83_08455	COG1105	Belongs to the carbohydrate kinase PfkB family
C7H83_08460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_08460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_08460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_08465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7H83_08470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7H83_08475	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7H83_08495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7H83_08505	COG2365	Tyrosine phosphatase family
C7H83_08520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7H83_08525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7H83_08545	COG0481	GTPase activity
C7H83_08555	COG0628	permease
C7H83_08560	COG0542	response to heat
C7H83_08570	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7H83_08575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7H83_08580	COG2384	SAM-dependent methyltransferase
C7H83_08585	COG1484	DNA-dependent DNA replication
C7H83_08595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7H83_08600	COG0237	dephospho-CoA kinase activity
C7H83_08605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7H83_08610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7H83_08610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7H83_08625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7H83_08630	COG3091	SprT-like family
C7H83_08635	COG2183	response to ionizing radiation
C7H83_08655	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7H83_08660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7H83_08665	COG0742	ribosomal rna small subunit methyltransferase
C7H83_08670	COG4471	UPF0298 protein
C7H83_08675	COG3679	Belongs to the UPF0342 family
C7H83_08685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7H83_08690	COG0772	Belongs to the SEDS family
C7H83_08695	COG4838	Belongs to the UPF0358 family
C7H83_08705	COG0483	inositol monophosphate 1-phosphatase activity
C7H83_08710	COG4476	Belongs to the UPF0223 family
C7H83_08745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7H83_08750	COG0516	GMP reductase activity
C7H83_08755	COG4989	oxidoreductase activity
C7H83_08760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7H83_08765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7H83_08770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7H83_08775	COG1966	Carbon starvation protein
C7H83_08780	COG3279	Response regulator of the LytR AlgR family
C7H83_08785	COG3275	phosphorelay sensor kinase activity
C7H83_08800	COG1876	peptidase activity
C7H83_08830	COG0436	Aminotransferase
C7H83_08850	COG1227	inorganic diphosphatase activity
C7H83_08855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7H83_08865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7H83_08870	COG0187	DNA topoisomerase II activity
C7H83_08875	COG1832	CoA-binding protein
C7H83_08880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7H83_08895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7H83_08900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7H83_08910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7H83_08915	COG0758	DNA mediated transformation
C7H83_08920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7H83_08925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7H83_08965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7H83_08970	COG0681	Belongs to the peptidase S26 family
C7H83_08975	COG3409	Peptidoglycan-binding domain 1 protein
C7H83_08975	COG0793	Belongs to the peptidase S41A family
C7H83_08980	COG4479	Belongs to the UPF0346 family
C7H83_08990	COG4698	Protein conserved in bacteria
C7H83_08995	COG2755	lipolytic protein G-D-S-L family
C7H83_09000	COG1307	EDD domain protein, DegV family
C7H83_09005	COG0371	Dehydrogenase
C7H83_09010	COG1272	protein, Hemolysin III
C7H83_09025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7H83_09030	COG0488	(ABC) transporter
C7H83_09035	COG0768	penicillin binding
C7H83_09040	COG1316	TRANSCRIPTIONal
C7H83_09045	COG1682	transport, permease protein
C7H83_09050	COG1134	teichoic acid transport
C7H83_09055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7H83_09070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7H83_09075	COG2246	polysaccharide biosynthetic process
C7H83_09080	COG2246	polysaccharide biosynthetic process
C7H83_09085	COG3385	transposase activity
C7H83_09095	COG5521	maltodextrose utilization protein MalA
C7H83_09105	COG0463	Glycosyl transferase, family 2
C7H83_09125	COG4841	protein insertion into membrane
C7H83_09130	COG0569	domain protein
C7H83_09135	COG2197	response regulator
C7H83_09140	COG4585	Histidine kinase
C7H83_09150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7H83_09155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7H83_09160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7H83_09165	COG0438	transferase activity, transferring glycosyl groups
C7H83_09190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7H83_09205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7H83_09235	COG0436	Aminotransferase
C7H83_09245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7H83_09245	COG1199	ATP-dependent helicase activity
C7H83_09250	COG1278	Cold shock
C7H83_09260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7H83_09265	COG2217	Heavy metal translocating P-type atpase
C7H83_09285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7H83_09305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7H83_09325	COG2217	Heavy metal translocating P-type atpase
C7H83_09330	COG0640	Transcriptional regulator
C7H83_09360	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7H83_09370	COG1396	sequence-specific DNA binding
C7H83_09420	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7H83_09425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_09430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7H83_09430	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7H83_09435	COG0513	Belongs to the DEAD box helicase family
C7H83_09440	COG0673	inositol 2-dehydrogenase activity
C7H83_09450	COG1686	Belongs to the peptidase S11 family
C7H83_09470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7H83_09480	COG1254	Belongs to the acylphosphatase family
C7H83_09495	COG0751	glycine-tRNA ligase activity
C7H83_09500	COG0752	glycyl-tRNA synthetase alpha subunit
C7H83_09505	COG1381	Involved in DNA repair and RecF pathway recombination
C7H83_09510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7H83_09515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7H83_09520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7H83_09530	COG1702	phosphate starvation-inducible protein PhoH
C7H83_09535	COG1610	YqeY-like protein
C7H83_09540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7H83_09550	COG4536	flavin adenine dinucleotide binding
C7H83_09555	COG0735	belongs to the Fur family
C7H83_09560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7H83_09565	COG0083	homoserine kinase activity
C7H83_09575	COG0640	Transcriptional regulator
C7H83_09580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7H83_09585	COG2723	6-phospho-beta-galactosidase activity
C7H83_09590	COG0561	phosphatase activity
C7H83_09610	COG3763	UPF0154 protein
C7H83_09615	COG0656	L-ascorbic acid biosynthetic process
C7H83_09620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7H83_09630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7H83_09635	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7H83_09635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7H83_09655	COG0436	Aminotransferase
C7H83_09660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7H83_09670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7H83_09675	COG1464	Belongs to the NlpA lipoprotein family
C7H83_09680	COG1609	Transcriptional regulator
C7H83_09705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7H83_09710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7H83_09715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_09720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7H83_09745	COG0745	RESPONSE REGULATOR receiver
C7H83_09750	COG5002	protein histidine kinase activity
C7H83_09755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7H83_09760	COG1950	PFAM Membrane protein of
C7H83_09775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7H83_09780	COG1950	PFAM Membrane protein of
C7H83_09795	COG0704	Plays a role in the regulation of phosphate uptake
C7H83_09800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7H83_09805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7H83_09810	COG0581	inorganic phosphate transmembrane transporter activity
C7H83_09815	COG0573	inorganic phosphate transmembrane transporter activity
C7H83_09820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7H83_09830	COG2177	Part of the ABC transporter FtsEX involved in
C7H83_09835	COG2884	Cell division ATP-binding protein ftsE
C7H83_09845	COG0653	protein targeting
C7H83_09860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7H83_09870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_09880	COG1739	Uncharacterized protein family UPF0029
C7H83_09905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7H83_09915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7H83_09925	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7H83_09930	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7H83_09935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7H83_09940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7H83_09945	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7H83_09950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7H83_09955	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7H83_09960	COG0356	it plays a direct role in the translocation of protons across the membrane
C7H83_09965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7H83_09970	COG0557	exoribonuclease II activity
C7H83_09980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7H83_09985	COG0148	phosphopyruvate hydratase activity
C7H83_09990	COG0149	triose-phosphate isomerase activity
C7H83_09995	COG0126	phosphoglycerate kinase activity
C7H83_10010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7H83_10260	COG0556	nucleotide-excision repair
C7H83_10330	COG0095	Lipoate-protein ligase
C7H83_10335	COG1078	dGTPase activity
C7H83_10340	COG2816	NAD+ diphosphatase activity
C7H83_10345	COG0346	lactoylglutathione lyase activity
C7H83_10355	COG3118	belongs to the thioredoxin family
C7H83_10360	COG1193	negative regulation of DNA recombination
C7H83_10375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7H83_10385	COG2059	Chromate
C7H83_10410	COG4175	Glycine betaine
C7H83_10410	COG3448	diguanylate cyclase activity
C7H83_10415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7H83_10420	COG1464	Belongs to the NlpA lipoprotein family
C7H83_10430	COG3906	Belongs to the UPF0473 family
C7H83_10435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7H83_10440	COG4472	Bacterial protein of unknown function (DUF965)
C7H83_10445	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7H83_10450	COG0488	(ABC) transporter
C7H83_10455	COG0686	Belongs to the AlaDH PNT family
C7H83_10465	COG3328	transposase activity
C7H83_10475	COG0604	alcohol dehydrogenase
C7H83_10485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7H83_10490	COG4684	Psort location CytoplasmicMembrane, score
C7H83_10510	COG0800	Aldolase
C7H83_10515	COG4948	Mandelate Racemase Muconate Lactonizing
C7H83_10520	COG3711	transcriptional antiterminator
C7H83_10520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_10530	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_10595	COG1943	Transposase
C7H83_10600	COG0765	amino acid transport
C7H83_10605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_10610	COG1373	ATPase (AAA superfamily
C7H83_10655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_10660	COG2855	membrane
C7H83_10665	COG0583	DNA-binding transcription factor activity
C7H83_10670	COG2084	Dehydrogenase
C7H83_10675	COG1668	transmembrane transport
C7H83_10680	COG4152	abc transporter atp-binding protein
C7H83_10700	COG1607	acyl-coa hydrolase
C7H83_10705	COG0825	malonyl-CoA metabolic process
C7H83_10710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7H83_10715	COG0439	Biotin carboxylase
C7H83_10720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7H83_10725	COG0511	ligase activity, forming carbon-carbon bonds
C7H83_10735	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_10740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7H83_10745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7H83_10750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7H83_10755	COG1846	Transcriptional regulator
C7H83_10765	COG1428	Deoxynucleoside kinase
C7H83_10770	COG4703	Protein of unknown function (DUF1797)
C7H83_10775	COG2084	Dehydrogenase
C7H83_10780	COG0438	transferase activity, transferring glycosyl groups
C7H83_10795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7H83_10800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_10810	COG0542	response to heat
C7H83_10820	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7H83_10825	COG1253	flavin adenine dinucleotide binding
C7H83_10835	COG3557	Belongs to the UPF0374 family
C7H83_10845	COG2137	regulation of response to DNA damage stimulus
C7H83_10855	COG0442	prolyl-tRNA aminoacylation
C7H83_10860	COG0750	zinc metalloprotease
C7H83_10865	COG4589	Belongs to the CDS family
C7H83_10870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7H83_10875	COG0233	cytoplasmic translational termination
C7H83_10880	COG0528	UMP kinase activity
C7H83_10885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7H83_10890	COG0052	Belongs to the universal ribosomal protein uS2 family
C7H83_10895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7H83_10910	COG1214	PFAM Peptidase M22, glycoprotease
C7H83_10940	COG1609	Transcriptional regulator
C7H83_10950	COG1609	Transcriptional regulator
C7H83_10955	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7H83_10960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7H83_10965	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7H83_10970	COG2207	Transcriptional regulator
C7H83_10980	COG2814	Major facilitator Superfamily
C7H83_10990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7H83_10995	COG1940	carbohydrate kinase activity
C7H83_11010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7H83_11015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7H83_11035	COG0617	tRNA 3'-terminal CCA addition
C7H83_11040	COG1694	Mazg nucleotide pyrophosphohydrolase
C7H83_11045	COG5582	Belongs to the UPF0302 family
C7H83_11060	COG0776	regulation of translation
C7H83_11065	COG1160	GTP binding
C7H83_11070	COG0539	negative regulation of cytoplasmic translation
C7H83_11080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7H83_11090	COG0514	ATP-dependent DNA helicase (RecQ)
C7H83_11100	COG1141	Ferredoxin
C7H83_11105	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7H83_11110	COG1187	pseudouridine synthase activity
C7H83_11115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7H83_11120	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7H83_11125	COG4974	Belongs to the 'phage' integrase family
C7H83_11130	COG0735	belongs to the Fur family
C7H83_11135	COG2996	Protein conserved in bacteria
C7H83_11150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7H83_11155	COG0358	DNA primase activity
C7H83_11165	COG0741	lytic transglycosylase activity
C7H83_11185	COG3425	synthase
C7H83_11195	COG0656	L-ascorbic acid biosynthetic process
C7H83_11200	COG1464	Belongs to the NlpA lipoprotein family
C7H83_11220	COG1349	DNA-binding transcription factor activity
C7H83_11225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7H83_11240	COG2190	(PTS) system
C7H83_11250	COG0582	viral genome integration into host DNA
C7H83_11260	COG2207	Transcriptional regulator
C7H83_11285	COG3385	transposase activity
C7H83_11305	COG1131	(ABC) transporter
C7H83_11360	COG4585	Histidine kinase
C7H83_11410	COG0582	viral genome integration into host DNA
C7H83_11490	COG5002	protein histidine kinase activity
C7H83_11495	COG0745	RESPONSE REGULATOR receiver
C7H83_11500	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7H83_11530	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7H83_11535	COG1399	metal-binding, possibly nucleic acid-binding protein
C7H83_11545	COG0205	6-phosphofructokinase activity
C7H83_11550	COG0587	DNA-directed DNA polymerase activity
C7H83_11560	COG2252	PERMEase
C7H83_11565	COG0561	phosphatase activity
C7H83_11575	COG3385	transposase activity
C7H83_11600	COG0166	Belongs to the GPI family
C7H83_11605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7H83_11610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7H83_11620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7H83_11625	COG1368	sulfuric ester hydrolase activity
C7H83_11640	COG5002	protein histidine kinase activity
C7H83_11640	COG3850	Histidine kinase
C7H83_11645	COG0745	RESPONSE REGULATOR receiver
C7H83_11665	COG1956	GAF domain-containing protein
C7H83_11670	COG2848	UPF0210 protein
C7H83_11675	COG3830	Belongs to the UPF0237 family
C7H83_11685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7H83_11690	COG0336	Belongs to the RNA methyltransferase TrmD family
C7H83_11720	COG3052	prosthetic group binding
C7H83_11725	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C7H83_11735	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C7H83_11745	COG1943	Transposase
C7H83_11770	COG0511	ligase activity, forming carbon-carbon bonds
C7H83_11775	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C7H83_11785	COG1837	Belongs to the UPF0109 family
C7H83_11790	COG0228	four-way junction DNA binding
C7H83_11795	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7H83_11810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7H83_11815	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7H83_11820	COG0436	Aminotransferase
C7H83_11830	COG2608	mercury ion transmembrane transporter activity
C7H83_11835	COG3682	Transcriptional regulator
C7H83_11840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7H83_11845	COG1295	ribonuclease BN
C7H83_11850	COG0024	Methionine aminopeptidase
C7H83_11855	COG0716	FMN binding
C7H83_11860	COG1309	transcriptional regulator
C7H83_11865	COG2309	aminopeptidase activity
C7H83_11875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7H83_11880	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7H83_11895	COG3599	regulation of cell shape
C7H83_11900	COG2302	S4 RNA-binding domain
C7H83_11905	COG0762	integral membrane protein
C7H83_11910	COG1799	cell septum assembly
C7H83_11915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7H83_11940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7H83_11950	COG0768	penicillin binding
C7H83_11965	COG2001	Belongs to the MraZ family
C7H83_11985	COG0497	DNA recombination
C7H83_11990	COG1438	arginine binding
C7H83_11995	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7H83_12005	COG1722	exodeoxyribonuclease VII activity
C7H83_12010	COG1570	exodeoxyribonuclease VII activity
C7H83_12015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7H83_12020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7H83_12025	COG1302	Protein conserved in bacteria
C7H83_12030	COG0006	proline dipeptidase activity
C7H83_12040	COG4864	UPF0365 protein
C7H83_12060	COG3716	PTS system mannose fructose sorbose family IID component
C7H83_12065	COG3715	PTS system
C7H83_12075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_12075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_12080	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7H83_12080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7H83_12090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7H83_12095	COG2868	ribosomal protein
C7H83_12100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7H83_12155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_12160	COG0563	adenylate kinase activity
C7H83_12165	COG3328	transposase activity
C7H83_12170	COG2217	Heavy metal translocating P-type atpase
C7H83_12180	COG2217	Heavy metal translocating P-type atpase
C7H83_12190	COG3682	Transcriptional regulator
C7H83_12195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7H83_12200	COG0656	L-ascorbic acid biosynthetic process
C7H83_12205	COG0095	Lipoate-protein ligase
C7H83_12215	COG0602	queuosine metabolic process
C7H83_12235	COG4467	Involved in initiation control of chromosome replication
C7H83_12245	COG0470	DNA polymerase III
C7H83_12250	COG3870	Protein conserved in bacteria
C7H83_12255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7H83_12260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7H83_12265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7H83_12270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7H83_12275	COG2723	6-phospho-beta-galactosidase activity
C7H83_12280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_12285	COG2910	NAD(P)H-binding
C7H83_12290	COG0222	ribosome binding
C7H83_12295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7H83_12300	COG0081	regulation of translation
C7H83_12315	COG0250	Participates in transcription elongation, termination and antitermination
C7H83_12320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7H83_12325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7H83_12335	COG1597	lipid kinase activity
C7H83_12345	COG4708	membrane
C7H83_12350	COG1943	Transposase
C7H83_12355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7H83_12365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7H83_12370	COG0500	methyltransferase
C7H83_12375	COG3142	Participates in the control of copper homeostasis
C7H83_12380	COG2239	Acts as a magnesium transporter
C7H83_12385	COG0564	pseudouridine synthase activity
C7H83_12390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7H83_12395	COG2357	RelA SpoT domain protein
C7H83_12400	COG4116	CYTH
C7H83_12415	COG4862	establishment of competence for transformation
C7H83_12420	COG1393	Belongs to the ArsC family
C7H83_12425	COG1132	(ABC) transporter
C7H83_12430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7H83_12435	COG0419	ATPase involved in DNA repair
C7H83_12440	COG0420	3'-5' exonuclease activity
C7H83_12445	COG0204	Acyl-transferase
C7H83_12450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7H83_12455	COG2827	Endonuclease containing a URI domain
C7H83_12465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7H83_12480	COG1131	(ABC) transporter
C7H83_12490	COG4658	electron transport chain
C7H83_12495	COG4656	Part of a membrane complex involved in electron transport
C7H83_12500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7H83_12510	COG0095	Lipoate-protein ligase
C7H83_12520	COG0647	UMP catabolic process
C7H83_12525	COG4470	Protein conserved in bacteria
C7H83_12530	COG0737	Belongs to the 5'-nucleotidase family
C7H83_12545	COG0590	tRNA wobble adenosine to inosine editing
C7H83_12555	COG2738	Putative neutral zinc metallopeptidase
C7H83_12560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7H83_12565	COG0019	diaminopimelate decarboxylase activity
C7H83_12570	COG1473	amidohydrolase
C7H83_12580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7H83_12585	COG2171	N-acyltransferase activity
C7H83_12590	COG0028	Belongs to the TPP enzyme family
C7H83_12605	COG0493	'glutamate synthase
C7H83_12605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7H83_12610	COG0543	2 iron, 2 sulfur cluster binding
C7H83_12615	COG0716	FMN binding
C7H83_12625	COG0402	S-adenosylhomocysteine deaminase activity
C7H83_12635	COG3608	succinylglutamate desuccinylase aspartoacylase
C7H83_12635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7H83_12665	COG3608	succinylglutamate desuccinylase aspartoacylase
C7H83_12665	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7H83_12675	COG0719	Fe-S assembly protein
C7H83_12685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7H83_12695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_12700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_12700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_12700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_12710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_12710	COG3711	transcriptional antiterminator
C7H83_12715	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7H83_12755	COG1045	serine acetyltransferase
C7H83_12760	COG0626	cystathionine gamma-synthase activity
C7H83_12765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7H83_12770	COG0693	protein deglycase activity
C7H83_12775	COG3527	Alpha-acetolactate decarboxylase
C7H83_12780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7H83_12800	COG2226	methyltransferase
C7H83_12810	COG1125	glycine betaine transport
C7H83_12810	COG0517	IMP dehydrogenase activity
C7H83_12815	COG1174	glycine betaine transport
C7H83_12820	COG1132	(ABC) transporter
C7H83_12830	COG3104	oligopeptide transport
C7H83_12840	COG1428	Deoxynucleoside kinase
C7H83_12850	COG0431	NADPH-dependent FMN reductase
C7H83_12850	COG3976	FMN-binding domain protein
C7H83_12850	COG1053	succinate dehydrogenase
C7H83_12855	COG1070	Carbohydrate kinase
C7H83_12875	COG0114	fumarate hydratase activity
C7H83_12895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7H83_12905	COG1132	(ABC) transporter
C7H83_12910	COG1132	(ABC) transporter
C7H83_12925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7H83_12930	COG0719	Fe-S assembly protein
C7H83_12950	COG1185	polyribonucleotide nucleotidyltransferase activity
C7H83_12955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7H83_12965	COG0628	permease
C7H83_12975	COG2706	6-phosphogluconolactonase activity
C7H83_12980	COG0488	(ABC) transporter
C7H83_12995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7H83_13000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_13000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_13015	COG2239	Acts as a magnesium transporter
C7H83_13020	COG0675	Transposase, IS605 OrfB family
C7H83_13025	COG4608	Belongs to the ABC transporter superfamily
C7H83_13030	COG0444	Belongs to the ABC transporter superfamily
C7H83_13035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7H83_13040	COG0601	transmembrane transport
C7H83_13050	COG4166	transmembrane transport
C7H83_13055	COG4166	transmembrane transport
C7H83_13060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7H83_13065	COG1674	ftsk spoiiie
C7H83_13065	COG1280	lysine exporter protein (LysE YggA)
C7H83_13070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_13080	COG1126	abc transporter atp-binding protein
C7H83_13085	COG0765	amino acid transport
C7H83_13105	COG3842	ATPase activity
C7H83_13115	COG1943	Transposase
C7H83_13130	COG0482	sulfurtransferase activity
C7H83_13140	COG1104	cysteine desulfurase activity
C7H83_13145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7H83_13155	COG3590	peptidase
C7H83_13160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7H83_13180	COG3853	Toxic anion resistance protein (TelA)
C7H83_13185	COG0531	amino acid
C7H83_13195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7H83_13215	COG1490	D-aminoacyl-tRNA deacylase activity
C7H83_13220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7H83_13225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7H83_13230	COG2264	protein methyltransferase activity
C7H83_13235	COG2094	Belongs to the DNA glycosylase MPG family
C7H83_13240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7H83_13275	COG3385	transposase activity
C7H83_13290	COG3316	Transposase and inactivated derivatives
C7H83_13305	COG1131	(ABC) transporter
C7H83_13310	COG1131	(ABC) transporter
C7H83_13320	COG0783	Belongs to the Dps family
C7H83_13325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_13355	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C7H83_13360	COG3576	pyridoxamine 5-phosphate
C7H83_13370	COG2823	Periplasmic or secreted lipoprotein
C7H83_13370	COG1652	LysM domain
C7H83_13380	COG3316	Transposase and inactivated derivatives
C7H83_13410	COG0783	Belongs to the Dps family
C7H83_13435	COG3316	Transposase and inactivated derivatives