locus-tag	class	description
AC806_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AC806_00010	COG0592	DNA-directed DNA polymerase activity
AC806_00015	COG2501	S4 domain
AC806_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AC806_00025	COG0187	DNA topoisomerase II activity
AC806_00035	COG0360	Binds together with S18 to 16S ribosomal RNA
AC806_00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AC806_00055	COG0359	binds to the 23S rRNA
AC806_00060	COG0305	Participates in initiation and elongation during chromosome replication
AC806_00065	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AC806_00070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AC806_00080	COG0488	(ABC) transporter
AC806_00090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AC806_00095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AC806_00100	COG0656	L-ascorbic acid biosynthetic process
AC806_00105	COG0756	dUTP diphosphatase activity
AC806_00115	COG4956	integral membrane protein (PIN domain superfamily)
AC806_00120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC806_00125	COG0215	cysteine-tRNA ligase activity
AC806_00130	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AC806_00135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC806_00140	COG3688	RNA-binding protein containing a PIN domain
AC806_00150	COG4466	Protein conserved in bacteria
AC806_00155	COG1970	mechanosensitive ion channel activity
AC806_00165	COG0612	Peptidase, M16
AC806_00170	COG0612	Peptidase, M16
AC806_00175	COG1426	Protein conserved in bacteria
AC806_00180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC806_00185	COG1546	Belongs to the CinA family
AC806_00185	COG1058	Belongs to the CinA family
AC806_00190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AC806_00195	COG1418	mRNA catabolic process
AC806_00200	COG2188	Transcriptional regulator
AC806_00205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC806_00210	COG1554	hydrolase, family 65, central catalytic
AC806_00215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_00215	COG1263	PTS System
AC806_00220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AC806_00225	COG1121	(ABC) transporter
AC806_00230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AC806_00235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC806_00240	COG0105	UTP biosynthetic process
AC806_00245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AC806_00250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC806_00270	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AC806_00280	COG0351	phosphomethylpyrimidine kinase
AC806_00305	COG0194	GDP metabolic process
AC806_00310	COG1758	RNA polymerase activity
AC806_00315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AC806_00320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AC806_00325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC806_00325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AC806_00335	COG2815	serine threonine protein kinase
AC806_00335	COG0515	serine threonine protein kinase
AC806_00340	COG4463	regulation of RNA biosynthetic process
AC806_00345	COG0542	response to heat
AC806_00365	COG0456	acetyltransferase
AC806_00370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC806_00375	COG0142	geranyltranstransferase activity
AC806_00405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AC806_00415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC806_00420	COG0745	RESPONSE REGULATOR receiver
AC806_00435	COG2205	protein histidine kinase activity
AC806_00445	COG1028	Short-chain dehydrogenase reductase Sdr
AC806_00450	COG0488	(ABC) transporter
AC806_00460	COG0693	protein deglycase activity
AC806_00465	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AC806_00470	COG3414	Phosphotransferase system galactitol-specific IIB component
AC806_00475	COG3775	system Galactitol-specific IIC component
AC806_00495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AC806_00500	COG0671	phosphoesterase, PA-phosphatase related
AC806_00510	COG1388	LysM domain
AC806_00510	COG1705	Flagellar rod assembly protein muramidase FlgJ
AC806_00520	COG0495	leucyl-tRNA aminoacylation
AC806_00525	COG1764	response to oxidative stress
AC806_00535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC806_00540	COG2244	polysaccharide biosynthetic process
AC806_00545	COG1187	pseudouridine synthase activity
AC806_00550	COG0564	pseudouridine synthase activity
AC806_00555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC806_00560	COG3679	Belongs to the UPF0342 family
AC806_00565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AC806_00570	COG0315	cyclic pyranopterin monophosphate synthase activity
AC806_00585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AC806_00595	COG3344	reverse transcriptase
AC806_00615	COG2801	Transposase and inactivated derivatives
AC806_00625	COG3284	Transcriptional regulator
AC806_00630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC806_00635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AC806_00640	COG0022	dehydrogenase e1 component
AC806_00645	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC806_00655	COG3316	Transposase and inactivated derivatives
AC806_00665	COG0281	malic enzyme
AC806_00690	COG3316	Transposase and inactivated derivatives
AC806_00695	COG1309	transcriptional regulator
AC806_00700	COG1033	growth of symbiont in host cell
AC806_00700	COG2409	Drug exporters of the RND superfamily
AC806_00705	COG3316	Transposase and inactivated derivatives
AC806_00725	COG3481	metal-dependent phosphohydrolase, HD sub domain
AC806_00730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC806_00740	COG0537	adenosine 5'-monophosphoramidase activity
AC806_00760	COG1482	cell wall glycoprotein biosynthetic process
AC806_00770	COG2190	(PTS) system
AC806_00770	COG1263	PTS System
AC806_00770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_00775	COG3442	glutamine amidotransferase
AC806_00780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AC806_00785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AC806_00790	COG0681	Belongs to the peptidase S26 family
AC806_00795	COG0514	ATP-dependent DNA helicase (RecQ)
AC806_00800	COG0071	Belongs to the small heat shock protein (HSP20) family
AC806_00815	COG1435	thymidine kinase activity
AC806_00820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AC806_00825	COG2890	protein-(glutamine-N5) methyltransferase activity
AC806_00830	COG0009	L-threonylcarbamoyladenylate synthase
AC806_00835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AC806_00840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AC806_00855	COG0772	Belongs to the SEDS family
AC806_00870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AC806_00875	COG0572	uridine kinase
AC806_00880	COG3385	transposase activity
AC806_00895	COG1671	Belongs to the UPF0178 family
AC806_00900	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC806_00905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AC806_00915	COG0736	holo-[acyl-carrier-protein] synthase activity
AC806_00920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AC806_00925	COG2337	Toxic component of a toxin-antitoxin (TA) module
AC806_00935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AC806_00960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AC806_00970	COG0343	queuine tRNA-ribosyltransferase activity
AC806_00980	COG1304	FMN binding
AC806_00995	COG0083	homoserine kinase activity
AC806_01000	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC806_01005	COG0402	S-adenosylhomocysteine deaminase activity
AC806_01015	COG2508	Transcriptional regulator
AC806_01020	COG4166	transmembrane transport
AC806_01025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AC806_01030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AC806_01035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AC806_01045	COG0824	Thioesterase
AC806_01050	COG0124	histidyl-tRNA synthetase
AC806_01055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AC806_01060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AC806_01065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AC806_01065	COG2755	lipolytic protein G-D-S-L family
AC806_01070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC806_01075	COG1459	type II secretion system
AC806_01080	COG4537	Required for transformation and DNA binding
AC806_01110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AC806_01115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC806_01130	COG1363	Peptidase, m42
AC806_01135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC806_01140	COG0589	response to stress
AC806_01145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC806_01150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC806_01155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AC806_01160	COG0572	uridine kinase
AC806_01165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AC806_01180	COG0322	excinuclease ABC activity
AC806_01205	COG0492	ferredoxin-NADP+ reductase activity
AC806_01210	COG1846	Transcriptional regulator
AC806_01215	COG0386	Belongs to the glutathione peroxidase family
AC806_01220	COG3118	belongs to the thioredoxin family
AC806_01230	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AC806_01235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC806_01245	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AC806_01250	COG2376	Dihydroxyacetone kinase
AC806_01255	COG1461	Dihydroxyacetone kinase
AC806_01260	COG2188	Transcriptional regulator
AC806_01265	COG2222	sugar isomerase
AC806_01275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC806_01285	COG0702	epimerase
AC806_01295	COG2217	Heavy metal translocating P-type atpase
AC806_01305	COG1285	pathogenesis
AC806_01320	COG1269	ATP hydrolysis coupled proton transport
AC806_01325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AC806_01335	COG1527	subunit (C
AC806_01345	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AC806_01350	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
AC806_01355	COG1394	ATPase activity, coupled to movement of substances
AC806_01360	COG1073	alpha beta
AC806_01390	COG1940	carbohydrate kinase activity
AC806_01400	COG1695	Transcriptional regulator
AC806_01405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AC806_01410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC806_01420	COG0488	(ABC) transporter
AC806_01425	COG1136	(ABC) transporter
AC806_01425	COG0577	efflux transmembrane transporter activity
AC806_01425	COG1136	(ABC) transporter
AC806_01425	COG0577	efflux transmembrane transporter activity
AC806_01435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AC806_01450	COG0367	asparagine synthase
AC806_01465	COG2188	Transcriptional regulator
AC806_01470	COG3448	diguanylate cyclase activity
AC806_01470	COG4175	Glycine betaine
AC806_01500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AC806_01505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AC806_01515	COG0471	metal ion transport
AC806_01525	COG2213	PTS system mannitol-specific
AC806_01530	COG3711	transcriptional antiterminator
AC806_01535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_01540	COG0246	Mannitol dehydrogenase
AC806_01545	COG0363	glucosamine-6-phosphate deaminase activity
AC806_01550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AC806_01555	COG4109	DRTGG domain
AC806_01560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AC806_01575	COG1028	Short-chain dehydrogenase reductase Sdr
AC806_01590	COG0531	amino acid
AC806_01595	COG1082	Xylose isomerase domain protein TIM barrel
AC806_01600	COG1053	succinate dehydrogenase
AC806_01635	COG1408	metallophosphoesterase
AC806_01640	COG0084	hydrolase, TatD family'
AC806_01645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AC806_01650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AC806_01660	COG0402	S-adenosylhomocysteine deaminase activity
AC806_01685	COG3316	Transposase and inactivated derivatives
AC806_01695	COG1288	antiporter activity
AC806_01700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AC806_01705	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AC806_01710	COG1472	Belongs to the glycosyl hydrolase 3 family
AC806_01740	COG3448	diguanylate cyclase activity
AC806_01740	COG4175	Glycine betaine
AC806_01755	COG5039	Polysaccharide pyruvyl transferase
AC806_01760	COG2261	transglycosylase associated protein
AC806_01770	COG2249	NAD(P)H dehydrogenase (quinone) activity
AC806_01790	COG0628	permease
AC806_01810	COG1316	TRANSCRIPTIONal
AC806_01815	COG3944	biosynthesis protein
AC806_01820	COG0489	protein tyrosine kinase activity
AC806_01825	COG4464	protein tyrosine phosphatase activity
AC806_01835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AC806_01860	COG0438	transferase activity, transferring glycosyl groups
AC806_01885	COG1216	Glycosyl transferase, family 2
AC806_01885	COG0463	Glycosyl transferase, family 2
AC806_01920	COG0433	COG0433 Predicted ATPase
AC806_01955	COG1337	RAMP superfamily
AC806_01960	COG1567	CRISPR-associated RAMP protein, Csm4 family
AC806_02005	COG0517	IMP dehydrogenase activity
AC806_02005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AC806_02025	COG2002	toxin-antitoxin pair type II binding
AC806_02080	COG3177	Filamentation induced by cAMP protein fic
AC806_02130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_02135	COG3715	PTS system
AC806_02140	COG3716	PTS system mannose fructose sorbose family IID component
AC806_02145	COG1028	Short-chain dehydrogenase reductase Sdr
AC806_02165	COG3711	transcriptional antiterminator
AC806_02165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_02170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_02175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_02180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_02185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AC806_02200	COG0561	phosphatase activity
AC806_02230	COG2113	Glycine betaine
AC806_02235	COG1510	regulation of RNA biosynthetic process
AC806_02245	COG1454	alcohol dehydrogenase
AC806_02275	COG2814	Major facilitator Superfamily
AC806_02290	COG4975	Glucose uptake
AC806_02295	COG1869	D-ribose catabolic process
AC806_02305	COG2017	converts alpha-aldose to the beta-anomer
AC806_02310	COG2814	Major facilitator Superfamily
AC806_02350	COG1518	maintenance of DNA repeat elements
AC806_02360	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AC806_02375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AC806_02380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC806_02390	COG1953	Uracil, thiamine, allantoin
AC806_02405	COG0668	transmembrane transport
AC806_02420	COG1914	H( )-stimulated, divalent metal cation uptake system
AC806_02430	COG3385	transposase activity
AC806_02455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AC806_02480	COG1131	(ABC) transporter
AC806_02485	COG1131	(ABC) transporter
AC806_02495	COG2217	Heavy metal translocating P-type atpase
AC806_02505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AC806_02520	COG2610	gluconate transmembrane transporter activity
AC806_02525	COG2721	sulfolactate sulfo-lyase activity
AC806_02530	COG2084	Dehydrogenase
AC806_02535	COG4948	Mandelate Racemase Muconate Lactonizing
AC806_02540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC806_02545	COG1929	Belongs to the glycerate kinase type-1 family
AC806_02555	COG1447	Phosphotransferase system cellobiose-specific component IIA
AC806_02565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_02570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_02590	COG0549	Belongs to the carbamate kinase family
AC806_02605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AC806_02610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AC806_02615	COG2390	Transcriptional regulator
AC806_02630	COG2271	Major facilitator Superfamily
AC806_02640	COG4297	protein containing double-stranded beta helix domain
AC806_02645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AC806_02665	COG1454	alcohol dehydrogenase
AC806_02665	COG1012	belongs to the aldehyde dehydrogenase family
AC806_02670	COG1063	alcohol dehydrogenase
AC806_02675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AC806_02680	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AC806_02685	COG2376	Dihydroxyacetone kinase
AC806_02690	COG1461	Dihydroxyacetone kinase
AC806_02700	COG1349	DNA-binding transcription factor activity
AC806_02710	COG0698	ribose 5-phosphate isomerase
AC806_02725	COG2610	gluconate transmembrane transporter activity
AC806_02735	COG1737	Transcriptional regulator
AC806_02745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_02745	COG1263	PTS System
AC806_02750	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AC806_02760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_02760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_02765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AC806_02775	COG3711	transcriptional antiterminator
AC806_02775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_02785	COG3730	PTS system glucitol sorbitol-specific
AC806_02790	COG3732	PTS system glucitol sorbitol-specific
AC806_02810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC806_02815	COG2233	PERMEase
AC806_02825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AC806_02830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AC806_02835	COG1120	ATPase activity
AC806_02840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC806_02845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC806_02850	COG0477	Major facilitator Superfamily
AC806_02855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AC806_02860	COG0492	ferredoxin-NADP+ reductase activity
AC806_02870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AC806_02875	COG1098	S1 RNA binding domain
AC806_02950	COG0783	Belongs to the Dps family
AC806_02955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC806_02970	COG2217	Heavy metal translocating P-type atpase
AC806_02975	COG0693	protein deglycase activity
AC806_02990	COG0640	Transcriptional regulator
AC806_02995	COG0656	L-ascorbic acid biosynthetic process
AC806_03000	COG1917	Cupin 2, conserved barrel domain protein
AC806_03000	COG2207	Transcriptional regulator
AC806_03025	COG0697	spore germination
AC806_03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC806_03035	COG2205	protein histidine kinase activity
AC806_03040	COG0745	RESPONSE REGULATOR receiver
AC806_03055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC806_03085	COG3594	Acyltransferase
AC806_03090	COG3579	cysteine-type endopeptidase activity
AC806_03105	COG2814	Major facilitator Superfamily
AC806_03110	COG1823	symporter activity
AC806_03125	COG1801	Protein of unknown function DUF72
AC806_03130	COG0561	phosphatase activity
AC806_03140	COG4876	unkown
AC806_03145	COG4166	transmembrane transport
AC806_03150	COG0527	aspartate kinase activity
AC806_03155	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AC806_03160	COG1104	cysteine desulfurase activity
AC806_03165	COG0301	tRNA thio-modification
AC806_03170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AC806_03175	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AC806_03180	COG0525	valine-tRNA ligase activity
AC806_03185	COG0285	dihydrofolate synthase activity
AC806_03190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC806_03195	COG2003	Belongs to the UPF0758 family
AC806_03200	COG1278	Cold shock
AC806_03220	COG1132	(ABC) transporter
AC806_03235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AC806_03240	COG0740	serine-type endopeptidase activity
AC806_03250	COG0584	glycerophosphoryl diester phosphodiesterase
AC806_03255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AC806_03265	COG0789	Transcriptional regulator
AC806_03270	COG0174	glutamine synthetase
AC806_03275	COG0504	CTP synthase activity
AC806_03285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AC806_03290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AC806_03295	COG0254	rRNA binding
AC806_03335	COG2390	Transcriptional regulator
AC806_03385	COG0583	DNA-binding transcription factor activity
AC806_03400	COG0366	Alpha amylase catalytic
AC806_03420	COG4106	trans-aconitate 2-methyltransferase activity
AC806_03430	COG0640	Transcriptional regulator
AC806_03440	COG0604	alcohol dehydrogenase
AC806_03480	COG0745	RESPONSE REGULATOR receiver
AC806_03485	COG5002	protein histidine kinase activity
AC806_03505	COG1136	(ABC) transporter
AC806_03510	COG1733	regulation of RNA biosynthetic process
AC806_03515	COG1902	pentaerythritol trinitrate reductase activity
AC806_03520	COG2130	NADP-dependent
AC806_03525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AC806_03530	COG1464	Belongs to the NlpA lipoprotein family
AC806_03535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AC806_03540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC806_03545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AC806_03550	COG2169	Transcriptional regulator
AC806_03560	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
AC806_03570	COG0745	RESPONSE REGULATOR receiver
AC806_03575	COG0642	Histidine kinase
AC806_03585	COG0577	efflux transmembrane transporter activity
AC806_03600	COG2814	Major facilitator Superfamily
AC806_03605	COG1120	ATPase activity
AC806_03635	COG0367	asparagine synthase
AC806_03650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AC806_03655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC806_03675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AC806_03700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AC806_03705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_03705	COG3711	transcriptional antiterminator
AC806_03710	COG2723	6-phospho-beta-galactosidase activity
AC806_03720	COG1447	Phosphotransferase system cellobiose-specific component IIA
AC806_03730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_03745	COG0561	phosphatase activity
AC806_03775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AC806_03800	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC806_03835	COG0745	RESPONSE REGULATOR receiver
AC806_03840	COG5002	protein histidine kinase activity
AC806_03855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AC806_03880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AC806_03885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AC806_03890	COG1943	Transposase
AC806_03895	COG1368	sulfuric ester hydrolase activity
AC806_03900	COG0583	DNA-binding transcription factor activity
AC806_03905	COG1780	Probably involved in ribonucleotide reductase function
AC806_03920	COG0561	phosphatase activity
AC806_03925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AC806_03930	COG0280	phosphate acetyltransferase
AC806_03935	COG0802	atpase or kinase
AC806_03955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AC806_03960	COG2610	gluconate transmembrane transporter activity
AC806_03965	COG1929	Belongs to the glycerate kinase type-1 family
AC806_03980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_03985	COG1609	Transcriptional regulator
AC806_03995	COG2723	6-phospho-beta-galactosidase activity
AC806_04015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_04020	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AC806_04035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AC806_04055	COG4975	Glucose uptake
AC806_04065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AC806_04110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_04110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_04110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_04115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_04120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_04120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_04120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_04150	COG1011	Hydrolase
AC806_04155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC806_04160	COG0583	DNA-binding transcription factor activity
AC806_04180	COG1129	ABC transporter
AC806_04200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_04205	COG0277	FAD linked oxidase domain protein
AC806_04240	COG1609	Transcriptional regulator
AC806_04245	COG0366	Alpha amylase catalytic
AC806_04275	COG3711	transcriptional antiterminator
AC806_04295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AC806_04310	COG3715	PTS system
AC806_04315	COG3716	PTS system mannose fructose sorbose family IID component
AC806_04340	COG1609	Transcriptional regulator
AC806_04345	COG0366	Alpha amylase catalytic
AC806_04350	COG0366	Alpha amylase catalytic
AC806_04370	COG0673	inositol 2-dehydrogenase activity
AC806_04390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_04390	COG1263	PTS System
AC806_04390	COG2190	(PTS) system
AC806_04400	COG4166	transmembrane transport
AC806_04415	COG2723	6-phospho-beta-galactosidase activity
AC806_04420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_04440	COG3344	reverse transcriptase
AC806_04450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_04450	COG1263	PTS System
AC806_04455	COG1486	melibiose metabolic process
AC806_04460	COG1737	Transcriptional regulator
AC806_04470	COG2217	Heavy metal translocating P-type atpase
AC806_04485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC806_04510	COG2096	Adenosyltransferase
AC806_04515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC806_04540	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AC806_04545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AC806_04550	COG1534	Rna-binding protein
AC806_04555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AC806_04560	COG1713	HD superfamily hydrolase involved in NAD metabolism
AC806_04565	COG0799	negative regulation of ribosome biogenesis
AC806_04570	COG2226	methyltransferase
AC806_04575	COG1323	Belongs to the UPF0348 family
AC806_04580	COG0217	transcriptional regulatory protein
AC806_04600	COG3973	AAA domain
AC806_04625	COG3189	MarR family transcriptional regulator
AC806_04630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AC806_04635	COG0779	Required for maturation of 30S ribosomal subunits
AC806_04640	COG0195	Participates in both transcription termination and antitermination
AC806_04645	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AC806_04660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AC806_04665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AC806_04670	COG0196	riboflavin kinase activity
AC806_04705	COG3344	reverse transcriptase
AC806_04710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC806_04735	COG1126	abc transporter atp-binding protein
AC806_04740	COG0765	amino acid transport
AC806_04745	COG0556	nucleotide-excision repair
AC806_04750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AC806_04755	COG1660	Displays ATPase and GTPase activities
AC806_04760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AC806_04765	COG1481	regulation of sporulation
AC806_04775	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AC806_04805	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AC806_04810	COG1074	ATP-dependent DNA helicase activity
AC806_04815	COG1733	regulation of RNA biosynthetic process
AC806_04820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AC806_04825	COG0072	phenylalanine-tRNA ligase activity
AC806_04825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC806_04830	COG0180	Tryptophanyl-tRNA synthetase
AC806_04835	COG1126	abc transporter atp-binding protein
AC806_04840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC806_04845	COG0765	amino acid transport
AC806_04850	COG0765	amino acid transport
AC806_04855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AC806_04870	COG0517	IMP dehydrogenase activity
AC806_04875	COG0668	transmembrane transport
AC806_04880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AC806_04885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC806_04900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC806_04910	COG1234	tRNA 3'-trailer cleavage
AC806_04915	COG0300	oxidoreductase activity
AC806_04920	COG5416	Lipopolysaccharide assembly protein A domain
AC806_04925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AC806_04925	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AC806_04930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC806_04940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC806_04945	COG4224	UPF0291 protein
AC806_04955	COG1705	Flagellar rod assembly protein muramidase FlgJ
AC806_04955	COG1388	LysM domain
AC806_04960	COG0735	belongs to the Fur family
AC806_04965	COG3935	DnaD domain protein
AC806_04975	COG3331	DNA recombination
AC806_04980	COG4474	Belongs to the UPF0398 family
AC806_04985	COG3599	regulation of cell shape
AC806_04990	COG0116	Belongs to the methyltransferase superfamily
AC806_05025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC806_05035	COG1028	Short-chain dehydrogenase reductase Sdr
AC806_05050	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AC806_05055	COG1418	mRNA catabolic process
AC806_05065	COG0513	Belongs to the DEAD box helicase family
AC806_05070	COG2153	protein acetylation
AC806_05085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AC806_05100	COG0328	RNA-DNA hybrid ribonuclease activity
AC806_05110	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AC806_05120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AC806_05125	COG0564	pseudouridine synthase activity
AC806_05130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AC806_05140	COG0540	Belongs to the ATCase OTCase family
AC806_05145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AC806_05150	COG0505	Belongs to the CarA family
AC806_05155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AC806_05160	COG0284	orotidine-5'-phosphate decarboxylase activity
AC806_05165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AC806_05190	COG4120	Belongs to the binding-protein-dependent transport system permease family
AC806_05200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AC806_05205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AC806_05210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AC806_05215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AC806_05220	COG0287	Prephenate dehydrogenase
AC806_05230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AC806_05235	COG0077	Prephenate dehydratase
AC806_05240	COG1316	TRANSCRIPTIONal
AC806_05245	COG1307	EDD domain protein, DegV family
AC806_05250	COG2124	cytochrome p450
AC806_05270	COG0456	acetyltransferase
AC806_05280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC806_05290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AC806_05300	COG0753	catalase activity
AC806_05305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AC806_05315	COG1012	belongs to the aldehyde dehydrogenase family
AC806_05320	COG1388	LysM domain
AC806_05335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AC806_05350	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC806_05385	COG2151	metal-sulfur cluster biosynthetic enzyme
AC806_05390	COG1199	ATP-dependent helicase activity
AC806_05395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC806_05400	COG0406	alpha-ribazole phosphatase activity
AC806_05405	COG0268	Binds directly to 16S ribosomal RNA
AC806_05410	COG1466	dna polymerase III delta subunit
AC806_05415	COG2333	competence protein COMEC
AC806_05415	COG0658	competence protein
AC806_05420	COG2131	deaminase
AC806_05425	COG1555	photosystem II stabilization
AC806_05425	COG1596	polysaccharide export
AC806_05435	COG0436	Aminotransferase
AC806_05440	COG1126	abc transporter atp-binding protein
AC806_05445	COG0765	amino acid transport
AC806_05450	COG0519	Catalyzes the synthesis of GMP from XMP
AC806_05460	COG0702	epimerase
AC806_05465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AC806_05475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AC806_05480	COG0154	amidase activity
AC806_05485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AC806_05490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AC806_05495	COG0210	DNA helicase
AC806_05505	COG0038	chloride channel
AC806_05510	COG1349	DNA-binding transcription factor activity
AC806_05515	COG1105	Belongs to the carbohydrate kinase PfkB family
AC806_05520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_05520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_05520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_05525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AC806_05530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AC806_05535	COG0544	peptidyl-prolyl cis-trans isomerase activity
AC806_05555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC806_05570	COG2365	Tyrosine phosphatase family
AC806_05580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AC806_05585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC806_05605	COG0481	GTPase activity
AC806_05620	COG2801	Transposase and inactivated derivatives
AC806_05625	COG0628	permease
AC806_05630	COG0542	response to heat
AC806_05640	COG2195	Cleaves the N-terminal amino acid of tripeptides
AC806_05645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AC806_05650	COG2384	SAM-dependent methyltransferase
AC806_05655	COG1484	DNA-dependent DNA replication
AC806_05665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AC806_05670	COG0237	dephospho-CoA kinase activity
AC806_05675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AC806_05680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC806_05680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC806_05695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC806_05700	COG3091	SprT-like family
AC806_05705	COG2183	response to ionizing radiation
AC806_05725	COG3480	Lon protease (S16) C-terminal proteolytic domain
AC806_05730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AC806_05735	COG0742	ribosomal rna small subunit methyltransferase
AC806_05740	COG4471	UPF0298 protein
AC806_05745	COG3679	Belongs to the UPF0342 family
AC806_05755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AC806_05760	COG0772	Belongs to the SEDS family
AC806_05765	COG4838	Belongs to the UPF0358 family
AC806_05775	COG0483	inositol monophosphate 1-phosphatase activity
AC806_05780	COG4476	Belongs to the UPF0223 family
AC806_05810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AC806_05815	COG0516	GMP reductase activity
AC806_05820	COG4989	oxidoreductase activity
AC806_05825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AC806_05830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AC806_05835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC806_05840	COG1966	Carbon starvation protein
AC806_05845	COG3279	Response regulator of the LytR AlgR family
AC806_05850	COG3275	phosphorelay sensor kinase activity
AC806_05860	COG3942	CHAP domain
AC806_05860	COG1705	Flagellar rod assembly protein muramidase FlgJ
AC806_05865	COG1876	peptidase activity
AC806_05895	COG0436	Aminotransferase
AC806_05915	COG0667	Aldo Keto reductase
AC806_05920	COG0366	Alpha amylase catalytic
AC806_05920	COG3103	Sh3 type 3 domain protein
AC806_05930	COG3385	transposase activity
AC806_05955	COG1227	inorganic diphosphatase activity
AC806_05960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AC806_05975	COG0187	DNA topoisomerase II activity
AC806_05980	COG1832	CoA-binding protein
AC806_05985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AC806_06000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AC806_06005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AC806_06015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AC806_06020	COG0758	DNA mediated transformation
AC806_06025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AC806_06030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AC806_06065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AC806_06070	COG3385	transposase activity
AC806_06075	COG0681	Belongs to the peptidase S26 family
AC806_06080	COG0793	Belongs to the peptidase S41A family
AC806_06080	COG3409	Peptidoglycan-binding domain 1 protein
AC806_06085	COG4479	Belongs to the UPF0346 family
AC806_06095	COG4698	Protein conserved in bacteria
AC806_06100	COG2755	lipolytic protein G-D-S-L family
AC806_06105	COG1307	EDD domain protein, DegV family
AC806_06110	COG0371	Dehydrogenase
AC806_06115	COG1272	protein, Hemolysin III
AC806_06130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AC806_06135	COG0488	(ABC) transporter
AC806_06140	COG0768	penicillin binding
AC806_06150	COG1682	transport, permease protein
AC806_06155	COG1134	teichoic acid transport
AC806_06160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AC806_06170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AC806_06180	COG2246	polysaccharide biosynthetic process
AC806_06185	COG5521	maltodextrose utilization protein MalA
AC806_06195	COG0463	Glycosyl transferase, family 2
AC806_06200	COG1368	sulfuric ester hydrolase activity
AC806_06205	COG4841	protein insertion into membrane
AC806_06210	COG0569	domain protein
AC806_06215	COG2197	response regulator
AC806_06220	COG4585	Histidine kinase
AC806_06230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC806_06235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AC806_06265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC806_06285	COG0463	Glycosyl transferase, family 2
AC806_06285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC806_06300	COG3385	transposase activity
AC806_06305	COG2801	Transposase and inactivated derivatives
AC806_06310	COG2963	transposase activity
AC806_06320	COG2801	Transposase and inactivated derivatives
AC806_06330	COG0463	Glycosyl transferase, family 2
AC806_06330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC806_06340	COG2801	Transposase and inactivated derivatives
AC806_06355	COG0017	Asparaginyl-tRNA synthetase
AC806_06360	COG0436	Aminotransferase
AC806_06370	COG1199	ATP-dependent helicase activity
AC806_06370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC806_06375	COG1278	Cold shock
AC806_06385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AC806_06390	COG2217	Heavy metal translocating P-type atpase
AC806_06410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AC806_06430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC806_06450	COG1619	proteins homologs of microcin C7 resistance protein MccF
AC806_06460	COG1396	sequence-specific DNA binding
AC806_06490	COG1309	transcriptional regulator
AC806_06515	COG1447	Phosphotransferase system cellobiose-specific component IIA
AC806_06520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_06525	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AC806_06525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AC806_06530	COG0513	Belongs to the DEAD box helicase family
AC806_06535	COG0673	inositol 2-dehydrogenase activity
AC806_06545	COG1686	Belongs to the peptidase S11 family
AC806_06565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC806_06570	COG1254	Belongs to the acylphosphatase family
AC806_06585	COG0751	glycine-tRNA ligase activity
AC806_06590	COG0752	glycyl-tRNA synthetase alpha subunit
AC806_06595	COG1381	Involved in DNA repair and RecF pathway recombination
AC806_06600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AC806_06605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AC806_06610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AC806_06620	COG1702	phosphate starvation-inducible protein PhoH
AC806_06625	COG1610	YqeY-like protein
AC806_06630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AC806_06635	COG1732	Glycine betaine
AC806_06640	COG4536	flavin adenine dinucleotide binding
AC806_06645	COG0735	belongs to the Fur family
AC806_06650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AC806_06655	COG0083	homoserine kinase activity
AC806_06665	COG0640	Transcriptional regulator
AC806_06670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC806_06675	COG2723	6-phospho-beta-galactosidase activity
AC806_06685	COG1737	Transcriptional regulator
AC806_06690	COG3763	UPF0154 protein
AC806_06695	COG0656	L-ascorbic acid biosynthetic process
AC806_06700	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AC806_06710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AC806_06725	COG1609	Transcriptional regulator
AC806_06755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AC806_06760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AC806_06765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AC806_06770	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AC806_06795	COG0745	RESPONSE REGULATOR receiver
AC806_06800	COG5002	protein histidine kinase activity
AC806_06805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AC806_06810	COG1950	PFAM Membrane protein of
AC806_06825	COG0704	Plays a role in the regulation of phosphate uptake
AC806_06830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AC806_06835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AC806_06840	COG0581	inorganic phosphate transmembrane transporter activity
AC806_06845	COG0573	inorganic phosphate transmembrane transporter activity
AC806_06850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AC806_06860	COG2177	Part of the ABC transporter FtsEX involved in
AC806_06865	COG2884	Cell division ATP-binding protein ftsE
AC806_06870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AC806_06875	COG0653	protein targeting
AC806_06890	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AC806_06895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_06905	COG1739	Uncharacterized protein family UPF0029
AC806_06930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AC806_06940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AC806_06950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AC806_06955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AC806_06960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AC806_06965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AC806_06970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AC806_06975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AC806_06980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AC806_06985	COG0356	it plays a direct role in the translocation of protons across the membrane
AC806_06990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AC806_06995	COG0557	exoribonuclease II activity
AC806_07005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC806_07010	COG0148	phosphopyruvate hydratase activity
AC806_07015	COG0149	triose-phosphate isomerase activity
AC806_07020	COG0126	phosphoglycerate kinase activity
AC806_07030	COG2390	Transcriptional regulator
AC806_07035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AC806_07060	COG0095	Lipoate-protein ligase
AC806_07065	COG1078	dGTPase activity
AC806_07070	COG2816	NAD+ diphosphatase activity
AC806_07075	COG0346	lactoylglutathione lyase activity
AC806_07085	COG3118	belongs to the thioredoxin family
AC806_07090	COG1193	negative regulation of DNA recombination
AC806_07105	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AC806_07115	COG2059	Chromate
AC806_07140	COG3448	diguanylate cyclase activity
AC806_07140	COG4175	Glycine betaine
AC806_07145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC806_07150	COG1464	Belongs to the NlpA lipoprotein family
AC806_07160	COG3906	Belongs to the UPF0473 family
AC806_07165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AC806_07170	COG4472	Bacterial protein of unknown function (DUF965)
AC806_07175	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AC806_07180	COG0488	(ABC) transporter
AC806_07185	COG0686	Belongs to the AlaDH PNT family
AC806_07190	COG0346	lactoylglutathione lyase activity
AC806_07195	COG0604	alcohol dehydrogenase
AC806_07205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AC806_07210	COG4684	Psort location CytoplasmicMembrane, score
AC806_07230	COG0246	Mannitol dehydrogenase
AC806_07245	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AC806_07250	COG3716	PTS system mannose fructose sorbose family IID component
AC806_07255	COG3715	PTS system
AC806_07260	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_07285	COG3586	endonuclease activity
AC806_07290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AC806_07325	COG0765	amino acid transport
AC806_07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC806_07335	COG1373	ATPase (AAA superfamily
AC806_07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC806_07380	COG2855	membrane
AC806_07385	COG0583	DNA-binding transcription factor activity
AC806_07390	COG2084	Dehydrogenase
AC806_07395	COG1668	transmembrane transport
AC806_07400	COG4152	abc transporter atp-binding protein
AC806_07420	COG1607	acyl-coa hydrolase
AC806_07425	COG0825	malonyl-CoA metabolic process
AC806_07430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AC806_07435	COG0439	Biotin carboxylase
AC806_07440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC806_07445	COG0511	ligase activity, forming carbon-carbon bonds
AC806_07455	COG1028	Short-chain dehydrogenase reductase Sdr
AC806_07460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AC806_07465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC806_07470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC806_07475	COG1846	Transcriptional regulator
AC806_07485	COG1428	Deoxynucleoside kinase
AC806_07490	COG4703	Protein of unknown function (DUF1797)
AC806_07495	COG2084	Dehydrogenase
AC806_07500	COG0438	transferase activity, transferring glycosyl groups
AC806_07520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AC806_07525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_07535	COG0542	response to heat
AC806_07545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AC806_07550	COG1253	flavin adenine dinucleotide binding
AC806_07560	COG3557	Belongs to the UPF0374 family
AC806_07570	COG2137	regulation of response to DNA damage stimulus
AC806_07585	COG0442	prolyl-tRNA aminoacylation
AC806_07590	COG0750	zinc metalloprotease
AC806_07595	COG4589	Belongs to the CDS family
AC806_07600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AC806_07605	COG0233	cytoplasmic translational termination
AC806_07610	COG0528	UMP kinase activity
AC806_07615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AC806_07620	COG0052	Belongs to the universal ribosomal protein uS2 family
AC806_07625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AC806_07640	COG1214	PFAM Peptidase M22, glycoprotease
AC806_07660	COG1609	Transcriptional regulator
AC806_07665	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AC806_07670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AC806_07675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AC806_07680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AC806_07685	COG1940	carbohydrate kinase activity
AC806_07700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AC806_07705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AC806_07725	COG0617	tRNA 3'-terminal CCA addition
AC806_07730	COG1694	Mazg nucleotide pyrophosphohydrolase
AC806_07735	COG5582	Belongs to the UPF0302 family
AC806_07740	COG0457	Tetratricopeptide repeat
AC806_07750	COG0776	regulation of translation
AC806_07755	COG1160	GTP binding
AC806_07760	COG0539	negative regulation of cytoplasmic translation
AC806_07780	COG0514	ATP-dependent DNA helicase (RecQ)
AC806_07790	COG1141	Ferredoxin
AC806_07795	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AC806_07800	COG1187	pseudouridine synthase activity
AC806_07805	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AC806_07810	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AC806_07815	COG4974	Belongs to the 'phage' integrase family
AC806_07820	COG0735	belongs to the Fur family
AC806_07825	COG2996	Protein conserved in bacteria
AC806_07840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC806_07845	COG0358	DNA primase activity
AC806_07855	COG0741	lytic transglycosylase activity
AC806_07880	COG3425	synthase
AC806_07890	COG0656	L-ascorbic acid biosynthetic process
AC806_07895	COG1464	Belongs to the NlpA lipoprotein family
AC806_07900	COG5504	Zn-dependent protease
AC806_07910	COG3344	reverse transcriptase
AC806_07920	COG1349	DNA-binding transcription factor activity
AC806_07925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AC806_07940	COG2190	(PTS) system
AC806_08020	COG5002	protein histidine kinase activity
AC806_08025	COG0745	RESPONSE REGULATOR receiver
AC806_08030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AC806_08045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AC806_08060	COG0205	6-phosphofructokinase activity
AC806_08065	COG0587	DNA-directed DNA polymerase activity
AC806_08075	COG2252	PERMEase
AC806_08080	COG0561	phosphatase activity
AC806_08110	COG0166	Belongs to the GPI family
AC806_08115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AC806_08120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC806_08125	COG0710	3-dehydroquinate dehydratase activity
AC806_08130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AC806_08135	COG1368	sulfuric ester hydrolase activity
AC806_08150	COG5002	protein histidine kinase activity
AC806_08150	COG3850	Histidine kinase
AC806_08155	COG0745	RESPONSE REGULATOR receiver
AC806_08165	COG1956	GAF domain-containing protein
AC806_08170	COG2848	UPF0210 protein
AC806_08175	COG3830	Belongs to the UPF0237 family
AC806_08185	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AC806_08190	COG0336	Belongs to the RNA methyltransferase TrmD family
AC806_08220	COG3052	prosthetic group binding
AC806_08225	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AC806_08235	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AC806_08260	COG0511	ligase activity, forming carbon-carbon bonds
AC806_08265	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AC806_08275	COG1837	Belongs to the UPF0109 family
AC806_08280	COG0228	four-way junction DNA binding
AC806_08285	COG0655	NAD(P)H dehydrogenase (quinone) activity
AC806_08300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC806_08305	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AC806_08310	COG0436	Aminotransferase
AC806_08320	COG2608	mercury ion transmembrane transporter activity
AC806_08325	COG3682	Transcriptional regulator
AC806_08330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC806_08335	COG1295	ribonuclease BN
AC806_08340	COG0024	Methionine aminopeptidase
AC806_08345	COG0716	FMN binding
AC806_08350	COG1309	transcriptional regulator
AC806_08360	COG2309	aminopeptidase activity
AC806_08370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AC806_08375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AC806_08380	COG3599	regulation of cell shape
AC806_08385	COG2302	S4 RNA-binding domain
AC806_08390	COG1799	cell septum assembly
AC806_08395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AC806_08420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AC806_08430	COG0768	penicillin binding
AC806_08445	COG2001	Belongs to the MraZ family
AC806_08460	COG0497	DNA recombination
AC806_08465	COG1438	arginine binding
AC806_08470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AC806_08480	COG1722	exodeoxyribonuclease VII activity
AC806_08485	COG1570	exodeoxyribonuclease VII activity
AC806_08490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AC806_08495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC806_08500	COG1302	Protein conserved in bacteria
AC806_08505	COG0006	proline dipeptidase activity
AC806_08515	COG4864	UPF0365 protein
AC806_08530	COG3716	PTS system mannose fructose sorbose family IID component
AC806_08535	COG3715	PTS system
AC806_08545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_08545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_08550	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AC806_08550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AC806_08560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AC806_08570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AC806_08590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AC806_08595	COG0656	L-ascorbic acid biosynthetic process
AC806_08600	COG0095	Lipoate-protein ligase
AC806_08610	COG0602	queuosine metabolic process
AC806_08625	COG4467	Involved in initiation control of chromosome replication
AC806_08630	COG1774	PSP1 C-terminal conserved region
AC806_08635	COG0470	DNA polymerase III
AC806_08640	COG3870	Protein conserved in bacteria
AC806_08645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AC806_08650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AC806_08655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AC806_08660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AC806_08665	COG2723	6-phospho-beta-galactosidase activity
AC806_08670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_08680	COG0222	ribosome binding
AC806_08685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AC806_08690	COG0081	regulation of translation
AC806_08705	COG0250	Participates in transcription elongation, termination and antitermination
AC806_08710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC806_08715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AC806_08725	COG1597	lipid kinase activity
AC806_08735	COG4708	membrane
AC806_08740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AC806_08750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AC806_08760	COG0500	methyltransferase
AC806_08765	COG3142	Participates in the control of copper homeostasis
AC806_08770	COG2239	Acts as a magnesium transporter
AC806_08775	COG0564	pseudouridine synthase activity
AC806_08780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AC806_08785	COG2357	RelA SpoT domain protein
AC806_08790	COG4116	CYTH
AC806_08805	COG4862	establishment of competence for transformation
AC806_08810	COG1393	Belongs to the ArsC family
AC806_08820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AC806_08825	COG0419	ATPase involved in DNA repair
AC806_08830	COG0420	3'-5' exonuclease activity
AC806_08835	COG0204	Acyl-transferase
AC806_08840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AC806_08845	COG2827	Endonuclease containing a URI domain
AC806_08855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AC806_08870	COG1131	(ABC) transporter
AC806_08880	COG4658	electron transport chain
AC806_08885	COG4656	Part of a membrane complex involved in electron transport
AC806_08890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC806_08900	COG0095	Lipoate-protein ligase
AC806_08910	COG0647	UMP catabolic process
AC806_08915	COG4470	Protein conserved in bacteria
AC806_08920	COG0737	Belongs to the 5'-nucleotidase family
AC806_08930	COG0590	tRNA wobble adenosine to inosine editing
AC806_08940	COG2738	Putative neutral zinc metallopeptidase
AC806_08945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AC806_08950	COG0019	diaminopimelate decarboxylase activity
AC806_08955	COG1473	amidohydrolase
AC806_08965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AC806_08970	COG2171	N-acyltransferase activity
AC806_08975	COG0028	Belongs to the TPP enzyme family
AC806_08985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC806_08985	COG0493	'glutamate synthase
AC806_08990	COG0543	2 iron, 2 sulfur cluster binding
AC806_08995	COG0716	FMN binding
AC806_09020	COG0251	oxidation-reduction process
AC806_09030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AC806_09035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AC806_09050	COG0493	'glutamate synthase
AC806_09050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC806_09055	COG0402	S-adenosylhomocysteine deaminase activity
AC806_09065	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AC806_09065	COG3608	succinylglutamate desuccinylase aspartoacylase
AC806_09100	COG0719	Fe-S assembly protein
AC806_09115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AC806_09125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_09130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_09130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_09130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC806_09140	COG3711	transcriptional antiterminator
AC806_09140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC806_09155	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AC806_09180	COG1045	serine acetyltransferase
AC806_09185	COG0626	cystathionine gamma-synthase activity
AC806_09190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AC806_09195	COG0693	protein deglycase activity
AC806_09200	COG3527	Alpha-acetolactate decarboxylase
AC806_09205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AC806_09225	COG2226	methyltransferase
AC806_09235	COG1125	glycine betaine transport
AC806_09240	COG1174	glycine betaine transport
AC806_09245	COG1132	(ABC) transporter
AC806_09255	COG3104	oligopeptide transport
AC806_09260	COG1428	Deoxynucleoside kinase
AC806_09270	COG3976	FMN-binding domain protein
AC806_09270	COG0431	NADPH-dependent FMN reductase
AC806_09270	COG1053	succinate dehydrogenase
AC806_09275	COG1070	Carbohydrate kinase
AC806_09295	COG0114	fumarate hydratase activity
AC806_09315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC806_09325	COG1132	(ABC) transporter
AC806_09330	COG1132	(ABC) transporter
AC806_09345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AC806_09350	COG0719	Fe-S assembly protein
AC806_09370	COG1185	polyribonucleotide nucleotidyltransferase activity
AC806_09375	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AC806_09385	COG0628	permease
AC806_09395	COG2706	6-phosphogluconolactonase activity
AC806_09400	COG0488	(ABC) transporter
AC806_09415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AC806_09420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC806_09420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC806_09435	COG2239	Acts as a magnesium transporter
AC806_09440	COG0675	Transposase, IS605 OrfB family
AC806_09445	COG4608	Belongs to the ABC transporter superfamily
AC806_09450	COG0444	Belongs to the ABC transporter superfamily
AC806_09455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC806_09460	COG0601	transmembrane transport
AC806_09470	COG4166	transmembrane transport
AC806_09475	COG4166	transmembrane transport
AC806_09480	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AC806_09485	COG1674	ftsk spoiiie
AC806_09485	COG1280	lysine exporter protein (LysE YggA)
AC806_09490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC806_09495	COG1126	abc transporter atp-binding protein
AC806_09500	COG0765	amino acid transport
AC806_09505	COG2508	Transcriptional regulator
AC806_09510	COG3842	ATPase activity
AC806_09535	COG0482	sulfurtransferase activity
AC806_09545	COG1104	cysteine desulfurase activity
AC806_09550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC806_09565	COG3590	peptidase
AC806_09570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AC806_09660	COG0582	viral genome integration into host DNA
AC806_09670	COG3853	Toxic anion resistance protein (TelA)
AC806_09675	COG0531	amino acid
AC806_09685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AC806_09700	COG1490	D-aminoacyl-tRNA deacylase activity
AC806_09705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC806_09710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC806_09715	COG2264	protein methyltransferase activity
AC806_09720	COG2094	Belongs to the DNA glycosylase MPG family
AC806_09725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC806_09745	COG0589	response to stress
AC806_09755	COG0561	phosphatase activity
AC806_09760	COG0656	L-ascorbic acid biosynthetic process
AC806_09770	COG0656	L-ascorbic acid biosynthetic process
AC806_09775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AC806_09785	COG4473	ABC transporter
AC806_09790	COG1131	(ABC) transporter
AC806_09795	COG1132	(ABC) transporter
AC806_09810	COG0725	ABC transporter, periplasmic molybdate-binding protein
AC806_09815	COG0521	Mo-molybdopterin cofactor biosynthetic process
AC806_09835	COG0242	peptide deformylase activity
AC806_09840	COG1464	Belongs to the NlpA lipoprotein family
AC806_09845	COG2011	ABC-type metal ion transport system permease component
AC806_09850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AC806_09855	COG0110	maltose O-acetyltransferase activity
AC806_09865	COG0765	amino acid transport
AC806_09870	COG1126	abc transporter atp-binding protein
AC806_09875	COG1114	Component of the transport system for branched-chain amino acids
AC806_09885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AC806_09890	COG2255	four-way junction helicase activity
AC806_09905	COG1943	Transposase
AC806_09910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AC806_09935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AC806_09940	COG4550	Control of competence regulator ComK, YlbF/YmcA
AC806_09945	COG1692	metallophosphoesterase
AC806_09960	COG3316	Transposase and inactivated derivatives
AC806_09965	COG0561	phosphatase activity
AC806_09975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AC806_09990	COG3279	Response regulator of the LytR AlgR family
AC806_10000	COG1268	BioY protein
AC806_10005	COG4493	Belongs to the UPF0637 family
AC806_10025	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC806_10025	COG2918	glutathione biosynthetic process
AC806_10040	COG0552	protein localization to endoplasmic reticulum
AC806_10045	COG0561	phosphatase activity
AC806_10050	COG1196	nuclear chromosome segregation
AC806_10055	COG0571	ribonuclease III activity
AC806_10060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC806_10065	COG0416	fatty acid biosynthetic process
AC806_10070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AC806_10075	COG1461	Dihydroxyacetone kinase
AC806_10085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AC806_10105	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AC806_10140	COG4485	Bacterial membrane protein, YfhO
AC806_10145	COG0174	glutamine synthetase
AC806_10150	COG0101	tRNA pseudouridine synthase activity
AC806_10160	COG1122	ATPase activity
AC806_10165	COG1122	ATPase activity
AC806_10170	COG0203	ribosomal protein L17
AC806_10175	COG0202	RNA polymerase activity
AC806_10180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AC806_10185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC806_10190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AC806_10195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AC806_10200	COG0563	adenylate kinase activity
AC806_10205	COG0201	protein transport
AC806_10210	COG0200	Binds to the 23S rRNA
AC806_10215	COG1841	ribosomal large subunit assembly
AC806_10220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AC806_10225	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AC806_10230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AC806_10235	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AC806_10240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AC806_10245	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC806_10250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AC806_10255	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AC806_10260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AC806_10265	COG0255	Belongs to the universal ribosomal protein uL29 family
AC806_10275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AC806_10280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AC806_10285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AC806_10290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC806_10295	COG0089	rRNA binding
AC806_10300	COG0088	Forms part of the polypeptide exit tunnel
AC806_10305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AC806_10310	COG0051	transcription antitermination factor activity, RNA binding
AC806_10325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC806_10340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC806_10345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AC806_10350	COG0049	tRNA binding
AC806_10355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AC806_10360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AC806_10365	COG0588	phosphoglycerate mutase activity
AC806_10370	COG1979	alcohol dehydrogenase
AC806_10405	COG1744	ABC transporter substrate-binding protein PnrA-like
AC806_10410	COG0295	cytidine deaminase activity
AC806_10415	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AC806_10420	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AC806_10430	COG2813	Specifically methylates the guanine in position
AC806_10435	COG1072	(Pantothenic acid kinase))
AC806_10440	COG0519	Catalyzes the synthesis of GMP from XMP
AC806_10440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC806_10455	COG1396	sequence-specific DNA binding
AC806_10465	COG1114	Component of the transport system for branched-chain amino acids
AC806_10500	COG3316	Transposase and inactivated derivatives
AC806_10530	COG3316	Transposase and inactivated derivatives
AC806_10545	COG0640	Transcriptional regulator
AC806_10550	COG3385	transposase activity
AC806_10555	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC806_10560	COG0708	Exodeoxyribonuclease III
AC806_10565	COG0628	permease
AC806_10570	COG0471	metal ion transport
AC806_10575	COG0561	phosphatase activity
AC806_10585	COG1126	abc transporter atp-binding protein
AC806_10590	COG0765	amino acid transport
AC806_10595	COG0625	glutathione transferase activity
AC806_10600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC806_10605	COG0693	protein deglycase activity
AC806_10615	COG1694	Mazg nucleotide pyrophosphohydrolase
AC806_10625	COG2267	carboxylic ester hydrolase activity
AC806_10635	COG0789	Transcriptional regulator
AC806_10640	COG1286	toxin biosynthetic process
AC806_10665	COG0473	3-isopropylmalate dehydrogenase activity
AC806_10670	COG0471	metal ion transport
AC806_10675	COG1968	undecaprenyl-diphosphatase activity
AC806_10685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_10685	COG2190	(PTS) system
AC806_10685	COG1263	PTS System
AC806_10695	COG2340	Cysteine-rich secretory protein family
AC806_10700	COG1305	Transglutaminase-like
AC806_10710	COG0714	Associated with various cellular activities
AC806_10715	COG0435	Glutathione S-transferase
AC806_10725	COG3385	transposase activity
AC806_10730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC806_10735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AC806_10750	COG4591	ABC-type transport system involved in lipoprotein release permease component
AC806_10750	COG1136	(ABC) transporter
AC806_10755	COG1309	transcriptional regulator
AC806_10780	COG0574	Belongs to the PEP-utilizing enzyme family
AC806_10780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AC806_10785	COG0517	IMP dehydrogenase activity
AC806_10790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AC806_10795	COG0039	L-malate dehydrogenase activity
AC806_10800	COG1737	Transcriptional regulator
AC806_10805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AC806_10815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC806_10815	COG1263	PTS System
AC806_10820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AC806_10835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AC806_10985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AC806_10990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AC806_11005	COG0037	tRNA processing
AC806_11010	COG1098	S1 RNA binding domain
AC806_11020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AC806_11025	COG2244	polysaccharide biosynthetic process
AC806_11030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AC806_11035	COG0193	aminoacyl-tRNA hydrolase activity
AC806_11040	COG0039	L-malate dehydrogenase activity
AC806_11050	COG0217	transcriptional regulatory protein
AC806_11060	COG1012	belongs to the aldehyde dehydrogenase family
AC806_11070	COG2814	Major facilitator Superfamily
AC806_11080	COG1252	NADH dehydrogenase
AC806_11100	COG4166	transmembrane transport
AC806_11115	COG3443	Belongs to the bacterial solute-binding protein 9 family
AC806_11115	COG0803	Belongs to the bacterial solute-binding protein 9 family
AC806_11120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AC806_11125	COG4988	ABC transporter
AC806_11130	COG1294	oxidase, subunit
AC806_11135	COG1271	oxidase subunit
AC806_11150	COG4975	Glucose uptake
AC806_11160	COG0018	arginyl-trna synthetase
AC806_11165	COG2153	protein acetylation
AC806_11170	COG3385	transposase activity
AC806_11185	COG1846	Transcriptional regulator
AC806_11190	COG1288	antiporter activity
AC806_11195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC806_11200	COG0549	Belongs to the carbamate kinase family
AC806_11205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AC806_11210	COG2235	arginine
AC806_11215	COG1438	arginine binding
AC806_11220	COG1438	arginine binding
AC806_11230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_11230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AC806_11235	COG2723	6-phospho-beta-galactosidase activity
AC806_11240	COG1447	Phosphotransferase system cellobiose-specific component IIA
AC806_11245	COG3684	Belongs to the aldolase LacD family
AC806_11280	COG1349	DNA-binding transcription factor activity
AC806_11295	COG2267	carboxylic ester hydrolase activity
AC806_11300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AC806_11305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AC806_11310	COG0783	Belongs to the Dps family
AC806_11335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AC806_11340	COG1162	GTPase activity
AC806_11415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AC806_11430	COG0012	GTP binding
AC806_11435	COG4481	Protein conserved in bacteria
AC806_11440	COG1475	DNA binding
AC806_11445	COG1192	Involved in chromosome partitioning
AC806_11450	COG0357	Ribosomal RNA small subunit methyltransferase G
AC806_11455	COG1442	glycosyl transferase family 8
AC806_11475	COG0798	PFAM Bile acid sodium symporter
AC806_11490	COG1304	FMN binding
AC806_11495	COG1346	cytolysis
AC806_11500	COG1380	Effector of murein hydrolase LrgA
AC806_11520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AC806_11525	COG0445	tRNA wobble uridine modification
AC806_11530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AC806_11545	COG0706	membrane insertase activity
AC806_11550	COG0594	ribonuclease P activity
AC806_11555	COG0230	Belongs to the bacterial ribosomal protein bL34 family