locus-tag	class	description
C7K38_00010	COG3344	reverse transcriptase
C7K38_00035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7K38_00040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7K38_00055	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7K38_00060	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7K38_00085	COG2826	transposase and inactivated derivatives, IS30 family
C7K38_00090	COG0745	RESPONSE REGULATOR receiver
C7K38_00095	COG5002	protein histidine kinase activity
C7K38_00100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7K38_00105	COG1950	PFAM Membrane protein of
C7K38_00110	COG1983	PspC domain protein
C7K38_00120	COG0704	Plays a role in the regulation of phosphate uptake
C7K38_00125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7K38_00130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7K38_00135	COG0581	inorganic phosphate transmembrane transporter activity
C7K38_00140	COG0573	inorganic phosphate transmembrane transporter activity
C7K38_00145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7K38_00150	COG0477	Major facilitator Superfamily
C7K38_00155	COG2177	Part of the ABC transporter FtsEX involved in
C7K38_00160	COG2884	Cell division ATP-binding protein ftsE
C7K38_00170	COG0653	protein targeting
C7K38_00180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7K38_00185	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7K38_00190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K38_00200	COG1739	Uncharacterized protein family UPF0029
C7K38_00235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7K38_00250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7K38_00255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7K38_00260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7K38_00265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7K38_00270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7K38_00275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7K38_00280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7K38_00285	COG0356	it plays a direct role in the translocation of protons across the membrane
C7K38_00290	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7K38_00295	COG0557	exoribonuclease II activity
C7K38_00305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7K38_00310	COG0148	phosphopyruvate hydratase activity
C7K38_00315	COG0149	triose-phosphate isomerase activity
C7K38_00320	COG0126	phosphoglycerate kinase activity
C7K38_00330	COG2390	Transcriptional regulator
C7K38_00340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7K38_00350	COG1668	transmembrane transport
C7K38_00360	COG3343	RNA polymerase activity
C7K38_00370	COG0095	Lipoate-protein ligase
C7K38_00375	COG1078	dGTPase activity
C7K38_00385	COG0346	lactoylglutathione lyase activity
C7K38_00395	COG3118	belongs to the thioredoxin family
C7K38_00400	COG1193	negative regulation of DNA recombination
C7K38_00415	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7K38_00425	COG2059	Chromate
C7K38_00440	COG1063	alcohol dehydrogenase
C7K38_00455	COG4175	Glycine betaine
C7K38_00455	COG3448	diguanylate cyclase activity
C7K38_00465	COG5646	InterPro IPR014922
C7K38_00470	COG1464	Belongs to the NlpA lipoprotein family
C7K38_00475	COG3906	Belongs to the UPF0473 family
C7K38_00480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7K38_00485	COG4472	Bacterial protein of unknown function (DUF965)
C7K38_00490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7K38_00500	COG0488	(ABC) transporter
C7K38_00505	COG3344	reverse transcriptase
C7K38_00510	COG0686	Belongs to the AlaDH PNT family
C7K38_00515	COG0346	lactoylglutathione lyase activity
C7K38_00520	COG0604	alcohol dehydrogenase
C7K38_00530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7K38_00535	COG4684	Psort location CytoplasmicMembrane, score
C7K38_00540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7K38_00560	COG0802	atpase or kinase
C7K38_00565	COG0280	phosphate acetyltransferase
C7K38_00570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7K38_00575	COG0561	phosphatase activity
C7K38_00595	COG0583	DNA-binding transcription factor activity
C7K38_00600	COG1368	sulfuric ester hydrolase activity
C7K38_00605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7K38_00610	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7K38_00640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7K38_00655	COG5002	protein histidine kinase activity
C7K38_00660	COG0745	RESPONSE REGULATOR receiver
C7K38_00670	COG2226	methyltransferase
C7K38_00675	COG0789	Transcriptional regulator
C7K38_00680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7K38_00695	COG0583	DNA-binding transcription factor activity
C7K38_00705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7K38_00740	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7K38_00765	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7K38_00770	COG1733	regulation of RNA biosynthetic process
C7K38_00790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7K38_00795	COG0561	phosphatase activity
C7K38_00810	COG0604	alcohol dehydrogenase
C7K38_00835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7K38_00840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7K38_00855	COG0367	asparagine synthase
C7K38_00865	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7K38_00865	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7K38_00870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7K38_00890	COG0251	oxidation-reduction process
C7K38_00930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7K38_00935	COG2169	Transcriptional regulator
C7K38_00940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7K38_00945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7K38_00950	COG2130	NADP-dependent
C7K38_00955	COG3344	reverse transcriptase
C7K38_00960	COG1811	Na channel or pump
C7K38_00965	COG1902	pentaerythritol trinitrate reductase activity
C7K38_00975	COG1136	(ABC) transporter
C7K38_00995	COG5002	protein histidine kinase activity
C7K38_01035	COG1349	DNA-binding transcription factor activity
C7K38_01050	COG2390	Transcriptional regulator
C7K38_01085	COG4175	Glycine betaine
C7K38_01085	COG3448	diguanylate cyclase activity
C7K38_01090	COG2188	Transcriptional regulator
C7K38_01100	COG0254	rRNA binding
C7K38_01110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7K38_01115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7K38_01125	COG0504	CTP synthase activity
C7K38_01130	COG0174	glutamine synthetase
C7K38_01135	COG0789	Transcriptional regulator
C7K38_01145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7K38_01150	COG0584	glycerophosphoryl diester phosphodiesterase
C7K38_01160	COG0740	serine-type endopeptidase activity
C7K38_01165	COG0745	RESPONSE REGULATOR receiver
C7K38_01170	COG5002	protein histidine kinase activity
C7K38_01170	COG3850	Histidine kinase
C7K38_01185	COG1132	(ABC) transporter
C7K38_01205	COG1278	Cold shock
C7K38_01210	COG2003	Belongs to the UPF0758 family
C7K38_01215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7K38_01220	COG0285	dihydrofolate synthase activity
C7K38_01225	COG0525	valine-tRNA ligase activity
C7K38_01230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7K38_01235	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7K38_01240	COG0301	tRNA thio-modification
C7K38_01245	COG1104	cysteine desulfurase activity
C7K38_01250	COG3344	reverse transcriptase
C7K38_01255	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7K38_01260	COG0527	aspartate kinase activity
C7K38_01265	COG4166	transmembrane transport
C7K38_01270	COG4876	unkown
C7K38_01280	COG0561	phosphatase activity
C7K38_01285	COG1801	Protein of unknown function DUF72
C7K38_01295	COG1823	symporter activity
C7K38_01300	COG2814	Major facilitator Superfamily
C7K38_01305	COG3579	cysteine-type endopeptidase activity
C7K38_01310	COG3594	Acyltransferase
C7K38_01320	COG3344	reverse transcriptase
C7K38_01350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7K38_01355	COG2814	Major facilitator Superfamily
C7K38_01370	COG0431	NADPH-dependent FMN reductase
C7K38_01375	COG2315	Protein conserved in bacteria
C7K38_01380	COG1733	regulation of RNA biosynthetic process
C7K38_01385	COG1902	pentaerythritol trinitrate reductase activity
C7K38_01395	COG1263	PTS System
C7K38_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_01395	COG2190	(PTS) system
C7K38_01400	COG1737	Transcriptional regulator
C7K38_01410	COG4978	Transcriptional regulator
C7K38_01410	COG0789	Transcriptional regulator
C7K38_01415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7K38_01435	COG0656	L-ascorbic acid biosynthetic process
C7K38_01440	COG0789	Transcriptional regulator
C7K38_01445	COG0516	GMP reductase activity
C7K38_01445	COG0517	IMP dehydrogenase activity
C7K38_01455	COG0411	ABC transporter
C7K38_01465	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7K38_01480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7K38_01515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7K38_01530	COG1073	alpha beta
C7K38_01535	COG1309	transcriptional regulator
C7K38_01565	COG1098	S1 RNA binding domain
C7K38_01570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7K38_01585	COG0492	ferredoxin-NADP+ reductase activity
C7K38_01590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7K38_01595	COG0477	Major facilitator Superfamily
C7K38_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7K38_01605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7K38_01610	COG1120	ATPase activity
C7K38_01615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7K38_01620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7K38_01630	COG2233	PERMEase
C7K38_01635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7K38_01640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7K38_01650	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7K38_01650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7K38_01655	COG2222	sugar isomerase
C7K38_01660	COG3716	PTS system mannose fructose sorbose family IID component
C7K38_01665	COG3715	PTS system
C7K38_01690	COG3732	PTS system glucitol sorbitol-specific
C7K38_01695	COG3730	PTS system glucitol sorbitol-specific
C7K38_01740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_01745	COG2217	Heavy metal translocating P-type atpase
C7K38_01750	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C7K38_01755	COG1263	PTS System
C7K38_01755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_01760	COG1486	melibiose metabolic process
C7K38_01765	COG1737	Transcriptional regulator
C7K38_01780	COG1012	belongs to the aldehyde dehydrogenase family
C7K38_01780	COG1454	alcohol dehydrogenase
C7K38_01790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7K38_01795	COG4297	protein containing double-stranded beta helix domain
C7K38_01810	COG0657	acetylesterase activity
C7K38_01810	COG2755	lipolytic protein G-D-S-L family
C7K38_01815	COG2390	Transcriptional regulator
C7K38_01820	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7K38_01825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7K38_01840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7K38_01845	COG2271	Major facilitator Superfamily
C7K38_01850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7K38_01855	COG3257	ureidoglycine aminohydrolase activity
C7K38_01860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7K38_01865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7K38_01870	COG0549	Belongs to the carbamate kinase family
C7K38_01885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7K38_01890	COG3835	regulator
C7K38_01900	COG3328	transposase activity
C7K38_01925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7K38_01935	COG1929	Belongs to the glycerate kinase type-1 family
C7K38_01940	COG4948	Mandelate Racemase Muconate Lactonizing
C7K38_01950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7K38_01955	COG4948	Mandelate Racemase Muconate Lactonizing
C7K38_01960	COG2084	Dehydrogenase
C7K38_01965	COG2610	gluconate transmembrane transporter activity
C7K38_01980	COG1012	belongs to the aldehyde dehydrogenase family
C7K38_01990	COG1131	(ABC) transporter
C7K38_01995	COG1131	(ABC) transporter
C7K38_02000	COG1309	transcriptional regulator
C7K38_02005	COG3711	transcriptional antiterminator
C7K38_02010	COG2723	6-phospho-beta-galactosidase activity
C7K38_02015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_02015	COG1263	PTS System
C7K38_02015	COG2190	(PTS) system
C7K38_02030	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7K38_02050	COG1914	H( )-stimulated, divalent metal cation uptake system
C7K38_02055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7K38_02060	COG4821	SIS domain
C7K38_02065	COG3716	PTS system mannose fructose sorbose family IID component
C7K38_02070	COG3715	PTS system
C7K38_02075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_02085	COG1396	sequence-specific DNA binding
C7K38_02100	COG0383	alpha-mannosidase activity
C7K38_02105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_02105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02110	COG1737	Transcriptional regulator
C7K38_02115	COG1263	PTS System
C7K38_02115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_02120	COG3394	polysaccharide catabolic process
C7K38_02125	COG1486	melibiose metabolic process
C7K38_02130	COG1737	Transcriptional regulator
C7K38_02160	COG3716	PTS system mannose fructose sorbose family IID component
C7K38_02165	COG3715	PTS system
C7K38_02170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_02180	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7K38_02180	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7K38_02190	COG2826	transposase and inactivated derivatives, IS30 family
C7K38_02195	COG0668	transmembrane transport
C7K38_02210	COG1953	Uracil, thiamine, allantoin
C7K38_02220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7K38_02225	COG0405	Gamma-glutamyltransferase
C7K38_02235	COG2188	Transcriptional regulator
C7K38_02245	COG2723	6-phospho-beta-galactosidase activity
C7K38_02255	COG0431	NADPH-dependent FMN reductase
C7K38_02255	COG3976	FMN-binding domain protein
C7K38_02255	COG1053	succinate dehydrogenase
C7K38_02285	COG0318	PFAM AMP-dependent synthetase and ligase
C7K38_02290	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7K38_02295	COG2050	protein possibly involved in aromatic compounds catabolism
C7K38_02300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7K38_02305	COG1263	PTS System
C7K38_02305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_02320	COG0383	alpha-mannosidase activity
C7K38_02325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_02330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_02335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_02340	COG3711	transcriptional antiterminator
C7K38_02340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_02355	COG1263	PTS System
C7K38_02355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_02385	COG3344	reverse transcriptase
C7K38_02405	COG2814	Major facilitator Superfamily
C7K38_02445	COG1454	alcohol dehydrogenase
C7K38_02455	COG1510	regulation of RNA biosynthetic process
C7K38_02460	COG2113	Glycine betaine
C7K38_02495	COG2188	Transcriptional regulator
C7K38_02505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7K38_02510	COG0783	Belongs to the Dps family
C7K38_02535	COG0582	viral genome integration into host DNA
C7K38_02540	COG2217	Heavy metal translocating P-type atpase
C7K38_02565	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C7K38_02600	COG3328	transposase activity
C7K38_02630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7K38_02635	COG0783	Belongs to the Dps family
C7K38_02650	COG0390	transport system, permease component
C7K38_02655	COG4619	ABC transporter
C7K38_02660	COG0662	Cupin 2, conserved barrel domain protein
C7K38_02695	COG0300	oxidoreductase activity
C7K38_02700	COG2723	6-phospho-beta-galactosidase activity
C7K38_02705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K38_02735	COG0438	transferase activity, transferring glycosyl groups
C7K38_02745	COG1215	transferase activity, transferring glycosyl groups
C7K38_02750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7K38_02755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7K38_02770	COG3385	transposase activity
C7K38_02780	COG4464	protein tyrosine phosphatase activity
C7K38_02785	COG0489	protein tyrosine kinase activity
C7K38_02795	COG1316	TRANSCRIPTIONal
C7K38_02805	COG3942	CHAP domain
C7K38_02805	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K38_02810	COG0628	permease
C7K38_02820	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7K38_02830	COG3344	reverse transcriptase
C7K38_02835	COG2261	transglycosylase associated protein
C7K38_02840	COG5039	Polysaccharide pyruvyl transferase
C7K38_02845	COG5039	Polysaccharide pyruvyl transferase
C7K38_02860	COG4175	Glycine betaine
C7K38_02860	COG3448	diguanylate cyclase activity
C7K38_02885	COG1472	Belongs to the glycosyl hydrolase 3 family
C7K38_02890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7K38_02895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7K38_02900	COG1288	antiporter activity
C7K38_02920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7K38_02925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7K38_02930	COG0084	hydrolase, TatD family'
C7K38_02935	COG1408	metallophosphoesterase
C7K38_02970	COG0531	amino acid
C7K38_02985	COG1028	Short-chain dehydrogenase reductase Sdr
C7K38_02995	COG1943	Transposase
C7K38_03000	COG3012	SEC-C Motif Domain Protein
C7K38_03005	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7K38_03010	COG4109	DRTGG domain
C7K38_03015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7K38_03020	COG0363	glucosamine-6-phosphate deaminase activity
C7K38_03025	COG0246	Mannitol dehydrogenase
C7K38_03030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_03035	COG3711	transcriptional antiterminator
C7K38_03040	COG2213	PTS system mannitol-specific
C7K38_03060	COG1428	Deoxynucleoside kinase
C7K38_03070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7K38_03075	COG0366	Alpha amylase catalytic
C7K38_03080	COG1136	(ABC) transporter
C7K38_03080	COG0577	efflux transmembrane transporter activity
C7K38_03080	COG1136	(ABC) transporter
C7K38_03080	COG0577	efflux transmembrane transporter activity
C7K38_03085	COG0488	(ABC) transporter
C7K38_03105	COG1695	Transcriptional regulator
C7K38_03115	COG1940	carbohydrate kinase activity
C7K38_03140	COG1394	ATPase activity, coupled to movement of substances
C7K38_03145	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
C7K38_03150	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
C7K38_03160	COG1527	subunit (C
C7K38_03170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7K38_03175	COG1269	ATP hydrolysis coupled proton transport
C7K38_03190	COG1285	pathogenesis
C7K38_03205	COG2217	Heavy metal translocating P-type atpase
C7K38_03215	COG0702	epimerase
C7K38_03250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_03260	COG3684	Belongs to the aldolase LacD family
C7K38_03265	COG2222	sugar isomerase
C7K38_03270	COG2188	Transcriptional regulator
C7K38_03275	COG1461	Dihydroxyacetone kinase
C7K38_03280	COG2376	Dihydroxyacetone kinase
C7K38_03285	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7K38_03290	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7K38_03300	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7K38_03310	COG3344	reverse transcriptase
C7K38_03315	COG3118	belongs to the thioredoxin family
C7K38_03320	COG0386	Belongs to the glutathione peroxidase family
C7K38_03325	COG1846	Transcriptional regulator
C7K38_03330	COG0492	ferredoxin-NADP+ reductase activity
C7K38_03355	COG0322	excinuclease ABC activity
C7K38_03360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7K38_03365	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7K38_03370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7K38_03375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7K38_03380	COG0589	response to stress
C7K38_03385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7K38_03390	COG1363	Peptidase, m42
C7K38_03405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7K38_03410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7K38_03415	COG0827	DNA restriction-modification system
C7K38_03440	COG4537	Required for transformation and DNA binding
C7K38_03445	COG1459	type II secretion system
C7K38_03450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7K38_03455	COG2755	lipolytic protein G-D-S-L family
C7K38_03455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7K38_03460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7K38_03465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7K38_03470	COG0124	histidyl-tRNA synthetase
C7K38_03475	COG0824	Thioesterase
C7K38_03485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7K38_03490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7K38_03495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7K38_03500	COG4166	transmembrane transport
C7K38_03505	COG2508	Transcriptional regulator
C7K38_03510	COG0402	S-adenosylhomocysteine deaminase activity
C7K38_03515	COG0402	S-adenosylhomocysteine deaminase activity
C7K38_03520	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7K38_03525	COG1428	Deoxynucleoside kinase
C7K38_03545	COG1304	FMN binding
C7K38_03555	COG0343	queuine tRNA-ribosyltransferase activity
C7K38_03570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7K38_03595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7K38_03610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7K38_03615	COG0736	holo-[acyl-carrier-protein] synthase activity
C7K38_03630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7K38_03635	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7K38_03640	COG1671	Belongs to the UPF0178 family
C7K38_03660	COG0572	uridine kinase
C7K38_03665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7K38_03670	COG0509	glycine decarboxylation via glycine cleavage system
C7K38_03675	COG1393	Belongs to the ArsC family
C7K38_03680	COG0772	Belongs to the SEDS family
C7K38_03690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7K38_03695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7K38_03700	COG0009	L-threonylcarbamoyladenylate synthase
C7K38_03705	COG2890	protein-(glutamine-N5) methyltransferase activity
C7K38_03710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7K38_03715	COG1435	thymidine kinase activity
C7K38_03730	COG0071	Belongs to the small heat shock protein (HSP20) family
C7K38_03735	COG0514	ATP-dependent DNA helicase (RecQ)
C7K38_03740	COG0681	Belongs to the peptidase S26 family
C7K38_03745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7K38_03750	COG1395	domain, Protein
C7K38_03755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7K38_03760	COG3442	glutamine amidotransferase
C7K38_03765	COG2190	(PTS) system
C7K38_03765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_03765	COG1263	PTS System
C7K38_03775	COG1482	cell wall glycoprotein biosynthetic process
C7K38_03780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7K38_03790	COG0537	adenosine 5'-monophosphoramidase activity
C7K38_03800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7K38_03805	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7K38_03825	COG3679	Belongs to the UPF0342 family
C7K38_03830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7K38_03835	COG0564	pseudouridine synthase activity
C7K38_03840	COG1187	pseudouridine synthase activity
C7K38_03845	COG2244	polysaccharide biosynthetic process
C7K38_03850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7K38_03860	COG1764	response to oxidative stress
C7K38_03865	COG1929	Belongs to the glycerate kinase type-1 family
C7K38_03870	COG0495	leucyl-tRNA aminoacylation
C7K38_03875	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K38_03875	COG1388	LysM domain
C7K38_03880	COG0671	phosphoesterase, PA-phosphatase related
C7K38_03885	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7K38_03905	COG3775	system Galactitol-specific IIC component
C7K38_03910	COG3414	Phosphotransferase system galactitol-specific IIB component
C7K38_03915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7K38_03920	COG0693	protein deglycase activity
C7K38_03930	COG0488	(ABC) transporter
C7K38_03935	COG1464	Belongs to the NlpA lipoprotein family
C7K38_03940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7K38_03945	COG1028	Short-chain dehydrogenase reductase Sdr
C7K38_03960	COG2723	6-phospho-beta-galactosidase activity
C7K38_03970	COG2205	protein histidine kinase activity
C7K38_03985	COG0745	RESPONSE REGULATOR receiver
C7K38_03995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7K38_04000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7K38_04040	COG0142	geranyltranstransferase activity
C7K38_04045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7K38_04050	COG0456	acetyltransferase
C7K38_04060	COG0542	response to heat
C7K38_04065	COG4463	regulation of RNA biosynthetic process
C7K38_04070	COG0515	serine threonine protein kinase
C7K38_04070	COG2815	serine threonine protein kinase
C7K38_04080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7K38_04080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7K38_04085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7K38_04090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7K38_04095	COG1758	RNA polymerase activity
C7K38_04100	COG0194	GDP metabolic process
C7K38_04105	COG4443	Transcriptional Coactivator p15 (PC4)
C7K38_04120	COG0351	phosphomethylpyrimidine kinase
C7K38_04130	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7K38_04145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7K38_04150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7K38_04155	COG0105	UTP biosynthetic process
C7K38_04160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7K38_04165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7K38_04170	COG1121	(ABC) transporter
C7K38_04175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7K38_04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_04180	COG1263	PTS System
C7K38_04185	COG1554	hydrolase, family 65, central catalytic
C7K38_04190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7K38_04195	COG2188	Transcriptional regulator
C7K38_04200	COG1418	mRNA catabolic process
C7K38_04205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7K38_04210	COG1546	Belongs to the CinA family
C7K38_04210	COG1058	Belongs to the CinA family
C7K38_04215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7K38_04220	COG1426	Protein conserved in bacteria
C7K38_04230	COG0612	Peptidase, M16
C7K38_04235	COG0612	Peptidase, M16
C7K38_04240	COG1970	mechanosensitive ion channel activity
C7K38_04245	COG4466	Protein conserved in bacteria
C7K38_04255	COG3688	RNA-binding protein containing a PIN domain
C7K38_04260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7K38_04265	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7K38_04270	COG0215	cysteine-tRNA ligase activity
C7K38_04275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7K38_04280	COG4956	integral membrane protein (PIN domain superfamily)
C7K38_04290	COG0756	dUTP diphosphatase activity
C7K38_04295	COG0656	L-ascorbic acid biosynthetic process
C7K38_04300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7K38_04305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7K38_04325	COG0488	(ABC) transporter
C7K38_04335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7K38_04340	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7K38_04345	COG0305	Participates in initiation and elongation during chromosome replication
C7K38_04350	COG0359	binds to the 23S rRNA
C7K38_04360	COG3344	reverse transcriptase
C7K38_04365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7K38_04375	COG0360	Binds together with S18 to 16S ribosomal RNA
C7K38_04385	COG0187	DNA topoisomerase II activity
C7K38_04390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7K38_04400	COG3344	reverse transcriptase
C7K38_04405	COG0592	DNA-directed DNA polymerase activity
C7K38_04410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7K38_04420	COG0594	ribonuclease P activity
C7K38_04425	COG0706	membrane insertase activity
C7K38_04440	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7K38_04445	COG0445	tRNA wobble uridine modification
C7K38_04450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7K38_04465	COG0583	DNA-binding transcription factor activity
C7K38_04470	COG1380	Effector of murein hydrolase LrgA
C7K38_04475	COG1346	cytolysis
C7K38_04480	COG1304	FMN binding
C7K38_04505	COG1442	glycosyl transferase family 8
C7K38_04520	COG0357	Ribosomal RNA small subunit methyltransferase G
C7K38_04525	COG1192	Involved in chromosome partitioning
C7K38_04530	COG1475	DNA binding
C7K38_04535	COG4481	Protein conserved in bacteria
C7K38_04540	COG0012	GTP binding
C7K38_04555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7K38_04630	COG1162	GTPase activity
C7K38_04635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7K38_04660	COG3344	reverse transcriptase
C7K38_04665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7K38_04670	COG0783	Belongs to the Dps family
C7K38_04675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7K38_04680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7K38_04685	COG2267	carboxylic ester hydrolase activity
C7K38_04700	COG1349	DNA-binding transcription factor activity
C7K38_04730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7K38_04745	COG1438	arginine binding
C7K38_04750	COG2235	arginine
C7K38_04755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7K38_04765	COG2153	protein acetylation
C7K38_04770	COG0018	arginyl-trna synthetase
C7K38_04775	COG4975	Glucose uptake
C7K38_04790	COG1271	oxidase subunit
C7K38_04795	COG1294	oxidase, subunit
C7K38_04800	COG4988	ABC transporter
C7K38_04805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7K38_04815	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7K38_04815	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7K38_04830	COG4166	transmembrane transport
C7K38_04855	COG1252	NADH dehydrogenase
C7K38_04865	COG2814	Major facilitator Superfamily
C7K38_04875	COG1012	belongs to the aldehyde dehydrogenase family
C7K38_04880	COG2814	Major facilitator Superfamily
C7K38_04890	COG0217	transcriptional regulatory protein
C7K38_04900	COG0039	L-malate dehydrogenase activity
C7K38_04905	COG0193	aminoacyl-tRNA hydrolase activity
C7K38_04910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7K38_04915	COG2244	polysaccharide biosynthetic process
C7K38_04920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7K38_04930	COG1098	S1 RNA binding domain
C7K38_04935	COG0037	tRNA processing
C7K38_04945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7K38_04950	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7K38_04955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7K38_05105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7K38_05120	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7K38_05125	COG1263	PTS System
C7K38_05125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_05135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7K38_05140	COG1737	Transcriptional regulator
C7K38_05145	COG0039	L-malate dehydrogenase activity
C7K38_05155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7K38_05180	COG1309	transcriptional regulator
C7K38_05185	COG1136	(ABC) transporter
C7K38_05185	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7K38_05200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7K38_05205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7K38_05210	COG0435	Glutathione S-transferase
C7K38_05215	COG3344	reverse transcriptase
C7K38_05220	COG0714	Associated with various cellular activities
C7K38_05230	COG1305	Transglutaminase-like
C7K38_05235	COG2340	Cysteine-rich secretory protein family
C7K38_05245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_05245	COG1263	PTS System
C7K38_05245	COG2190	(PTS) system
C7K38_05260	COG1388	LysM domain
C7K38_05265	COG1968	undecaprenyl-diphosphatase activity
C7K38_05270	COG4585	Histidine kinase
C7K38_05275	COG2197	response regulator
C7K38_05290	COG1286	toxin biosynthetic process
C7K38_05295	COG0789	Transcriptional regulator
C7K38_05305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7K38_05315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7K38_05320	COG0625	glutathione transferase activity
C7K38_05325	COG0693	protein deglycase activity
C7K38_05330	COG0765	amino acid transport
C7K38_05340	COG1126	abc transporter atp-binding protein
C7K38_05350	COG0561	phosphatase activity
C7K38_05355	COG0471	metal ion transport
C7K38_05360	COG0628	permease
C7K38_05365	COG0708	Exodeoxyribonuclease III
C7K38_05395	COG2153	protein acetylation
C7K38_05420	COG1114	Component of the transport system for branched-chain amino acids
C7K38_05445	COG3708	Transcriptional regulator
C7K38_05445	COG2207	Transcriptional regulator
C7K38_05450	COG0693	protein deglycase activity
C7K38_05455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7K38_05455	COG0519	Catalyzes the synthesis of GMP from XMP
C7K38_05460	COG1072	(Pantothenic acid kinase))
C7K38_05465	COG2813	Specifically methylates the guanine in position
C7K38_05475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7K38_05480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7K38_05485	COG0295	cytidine deaminase activity
C7K38_05490	COG1744	ABC transporter substrate-binding protein PnrA-like
C7K38_05510	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7K38_05520	COG1979	alcohol dehydrogenase
C7K38_05525	COG0588	phosphoglycerate mutase activity
C7K38_05535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7K38_05545	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7K38_05550	COG0049	tRNA binding
C7K38_05555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7K38_05560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7K38_05565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7K38_05580	COG0051	transcription antitermination factor activity, RNA binding
C7K38_05585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7K38_05590	COG0088	Forms part of the polypeptide exit tunnel
C7K38_05595	COG0089	rRNA binding
C7K38_05600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7K38_05605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7K38_05610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7K38_05615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7K38_05620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7K38_05625	COG0255	Belongs to the universal ribosomal protein uL29 family
C7K38_05630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7K38_05635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7K38_05640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7K38_05645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7K38_05650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7K38_05655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7K38_05660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7K38_05665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7K38_05670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7K38_05675	COG1841	ribosomal large subunit assembly
C7K38_05680	COG0200	Binds to the 23S rRNA
C7K38_05690	COG0563	adenylate kinase activity
C7K38_05695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7K38_05700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7K38_05705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7K38_05715	COG0202	RNA polymerase activity
C7K38_05720	COG0203	ribosomal protein L17
C7K38_05725	COG1122	ATPase activity
C7K38_05730	COG1122	ATPase activity
C7K38_05740	COG0101	tRNA pseudouridine synthase activity
C7K38_05770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7K38_05800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7K38_05810	COG1461	Dihydroxyacetone kinase
C7K38_05815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7K38_05820	COG0416	fatty acid biosynthetic process
C7K38_05825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7K38_05830	COG0571	ribonuclease III activity
C7K38_05835	COG1196	nuclear chromosome segregation
C7K38_05840	COG0561	phosphatase activity
C7K38_05845	COG0552	protein localization to endoplasmic reticulum
C7K38_05850	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7K38_05850	COG2918	glutathione biosynthetic process
C7K38_05865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7K38_05870	COG4493	Belongs to the UPF0637 family
C7K38_05875	COG1268	BioY protein
C7K38_05880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7K38_05895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7K38_05900	COG0561	phosphatase activity
C7K38_05920	COG1692	metallophosphoesterase
C7K38_05925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7K38_05950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7K38_05960	COG2255	four-way junction helicase activity
C7K38_05965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7K38_05975	COG1114	Component of the transport system for branched-chain amino acids
C7K38_05980	COG1126	abc transporter atp-binding protein
C7K38_05985	COG0765	amino acid transport
C7K38_05995	COG0110	maltose O-acetyltransferase activity
C7K38_06000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7K38_06005	COG2011	ABC-type metal ion transport system permease component
C7K38_06010	COG1464	Belongs to the NlpA lipoprotein family
C7K38_06015	COG0242	peptide deformylase activity
C7K38_06030	COG1132	(ABC) transporter
C7K38_06035	COG1131	(ABC) transporter
C7K38_06050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7K38_06055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K38_06065	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7K38_06075	COG2723	6-phospho-beta-galactosidase activity
C7K38_06080	COG3711	transcriptional antiterminator
C7K38_06080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_06090	COG0656	L-ascorbic acid biosynthetic process
C7K38_06095	COG3344	reverse transcriptase
C7K38_06105	COG1611	Belongs to the LOG family
C7K38_06115	COG0656	L-ascorbic acid biosynthetic process
C7K38_06120	COG0561	phosphatase activity
C7K38_06125	COG1131	(ABC) transporter
C7K38_06135	COG0589	response to stress
C7K38_06155	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7K38_06160	COG2094	Belongs to the DNA glycosylase MPG family
C7K38_06165	COG2264	protein methyltransferase activity
C7K38_06170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7K38_06175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7K38_06180	COG1490	D-aminoacyl-tRNA deacylase activity
C7K38_06185	COG3344	reverse transcriptase
C7K38_06200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7K38_06210	COG0531	amino acid
C7K38_06215	COG3853	Toxic anion resistance protein (TelA)
C7K38_06235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7K38_06240	COG3590	peptidase
C7K38_06245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7K38_06250	COG1104	cysteine desulfurase activity
C7K38_06260	COG0482	sulfurtransferase activity
C7K38_06290	COG3842	ATPase activity
C7K38_06295	COG2508	Transcriptional regulator
C7K38_06300	COG0765	amino acid transport
C7K38_06305	COG1126	abc transporter atp-binding protein
C7K38_06315	COG1674	ftsk spoiiie
C7K38_06315	COG1280	lysine exporter protein (LysE YggA)
C7K38_06320	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7K38_06325	COG4166	transmembrane transport
C7K38_06335	COG0601	transmembrane transport
C7K38_06340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7K38_06345	COG0444	Belongs to the ABC transporter superfamily
C7K38_06350	COG4608	Belongs to the ABC transporter superfamily
C7K38_06360	COG2239	Acts as a magnesium transporter
C7K38_06380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7K38_06380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7K38_06385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7K38_06405	COG0488	(ABC) transporter
C7K38_06410	COG2706	6-phosphogluconolactonase activity
C7K38_06420	COG0628	permease
C7K38_06425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7K38_06430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7K38_06435	COG1185	polyribonucleotide nucleotidyltransferase activity
C7K38_06455	COG0719	Fe-S assembly protein
C7K38_06460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7K38_06470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7K38_06475	COG1132	(ABC) transporter
C7K38_06480	COG1132	(ABC) transporter
C7K38_06490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7K38_06525	COG2610	gluconate transmembrane transporter activity
C7K38_06530	COG1070	Carbohydrate kinase
C7K38_06540	COG3976	FMN-binding domain protein
C7K38_06540	COG0431	NADPH-dependent FMN reductase
C7K38_06540	COG1053	succinate dehydrogenase
C7K38_06550	COG1428	Deoxynucleoside kinase
C7K38_06555	COG3104	oligopeptide transport
C7K38_06565	COG1132	(ABC) transporter
C7K38_06570	COG1174	glycine betaine transport
C7K38_06575	COG1125	glycine betaine transport
C7K38_06575	COG0517	IMP dehydrogenase activity
C7K38_06585	COG2226	methyltransferase
C7K38_06605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7K38_06610	COG3527	Alpha-acetolactate decarboxylase
C7K38_06620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7K38_06625	COG0626	cystathionine gamma-synthase activity
C7K38_06630	COG1045	serine acetyltransferase
C7K38_06635	COG0095	Lipoate-protein ligase
C7K38_06640	COG0025	NhaP-type Na H and K H
C7K38_06650	COG3711	transcriptional antiterminator
C7K38_06650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_06655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_06655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7K38_06655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_06660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_06665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_06675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7K38_06685	COG0719	Fe-S assembly protein
C7K38_06690	COG0716	FMN binding
C7K38_06695	COG0028	Belongs to the TPP enzyme family
C7K38_06710	COG2171	N-acyltransferase activity
C7K38_06715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7K38_06725	COG1473	amidohydrolase
C7K38_06730	COG0019	diaminopimelate decarboxylase activity
C7K38_06735	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7K38_06740	COG2738	Putative neutral zinc metallopeptidase
C7K38_06750	COG0590	tRNA wobble adenosine to inosine editing
C7K38_06765	COG0737	Belongs to the 5'-nucleotidase family
C7K38_06770	COG4470	Protein conserved in bacteria
C7K38_06775	COG0647	UMP catabolic process
C7K38_06785	COG0095	Lipoate-protein ligase
C7K38_06795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7K38_06800	COG4656	Part of a membrane complex involved in electron transport
C7K38_06805	COG4658	electron transport chain
C7K38_06815	COG1131	(ABC) transporter
C7K38_06820	COG1309	transcriptional regulator
C7K38_06825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7K38_06830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7K38_06835	COG2827	Endonuclease containing a URI domain
C7K38_06840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7K38_06855	COG0204	Acyl-transferase
C7K38_06860	COG0420	3'-5' exonuclease activity
C7K38_06865	COG0419	ATPase involved in DNA repair
C7K38_06870	COG0419	ATPase involved in DNA repair
C7K38_06875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7K38_06880	COG1393	Belongs to the ArsC family
C7K38_06885	COG4862	establishment of competence for transformation
C7K38_06905	COG4116	CYTH
C7K38_06910	COG2357	RelA SpoT domain protein
C7K38_06915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7K38_06920	COG0564	pseudouridine synthase activity
C7K38_06925	COG2239	Acts as a magnesium transporter
C7K38_06930	COG3142	Participates in the control of copper homeostasis
C7K38_06935	COG0500	methyltransferase
C7K38_06940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7K38_06950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7K38_06955	COG1597	lipid kinase activity
C7K38_06965	COG4708	membrane
C7K38_06975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7K38_06980	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7K38_06985	COG0250	Participates in transcription elongation, termination and antitermination
C7K38_06990	COG3344	reverse transcriptase
C7K38_07005	COG0081	regulation of translation
C7K38_07010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7K38_07015	COG0222	ribosome binding
C7K38_07020	COG2910	NAD(P)H-binding
C7K38_07025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K38_07030	COG2723	6-phospho-beta-galactosidase activity
C7K38_07035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7K38_07040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7K38_07045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7K38_07050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7K38_07055	COG3870	Protein conserved in bacteria
C7K38_07060	COG0470	DNA polymerase III
C7K38_07065	COG4467	Involved in initiation control of chromosome replication
C7K38_07090	COG1328	CTP reductase activity
C7K38_07095	COG0095	Lipoate-protein ligase
C7K38_07100	COG0656	L-ascorbic acid biosynthetic process
C7K38_07105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7K38_07120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7K38_07130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7K38_07140	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7K38_07140	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7K38_07145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_07145	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_07155	COG3715	PTS system
C7K38_07160	COG3716	PTS system mannose fructose sorbose family IID component
C7K38_07175	COG4864	UPF0365 protein
C7K38_07185	COG0006	proline dipeptidase activity
C7K38_07190	COG1302	Protein conserved in bacteria
C7K38_07195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7K38_07200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7K38_07205	COG1570	exodeoxyribonuclease VII activity
C7K38_07210	COG1722	exodeoxyribonuclease VII activity
C7K38_07215	COG0142	geranyltranstransferase activity
C7K38_07220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7K38_07225	COG1438	arginine binding
C7K38_07230	COG0497	DNA recombination
C7K38_07255	COG2001	Belongs to the MraZ family
C7K38_07260	COG0275	rRNA processing
C7K38_07270	COG0768	penicillin binding
C7K38_07280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7K38_07305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7K38_07310	COG1799	cell septum assembly
C7K38_07315	COG0762	integral membrane protein
C7K38_07320	COG2302	S4 RNA-binding domain
C7K38_07325	COG3599	regulation of cell shape
C7K38_07330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7K38_07335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7K38_07345	COG2309	aminopeptidase activity
C7K38_07350	COG1309	transcriptional regulator
C7K38_07355	COG0716	FMN binding
C7K38_07360	COG0024	Methionine aminopeptidase
C7K38_07380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7K38_07385	COG3682	Transcriptional regulator
C7K38_07390	COG2608	mercury ion transmembrane transporter activity
C7K38_07400	COG0436	Aminotransferase
C7K38_07405	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7K38_07410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7K38_07425	COG2826	transposase and inactivated derivatives, IS30 family
C7K38_07435	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7K38_07440	COG0431	NADPH-dependent FMN reductase
C7K38_07445	COG0228	four-way junction DNA binding
C7K38_07450	COG1837	Belongs to the UPF0109 family
C7K38_07460	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C7K38_07470	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C7K38_07475	COG3052	prosthetic group binding
C7K38_07510	COG0336	Belongs to the RNA methyltransferase TrmD family
C7K38_07515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7K38_07525	COG3830	Belongs to the UPF0237 family
C7K38_07530	COG2848	UPF0210 protein
C7K38_07535	COG1956	GAF domain-containing protein
C7K38_07545	COG0582	viral genome integration into host DNA
C7K38_07560	COG2826	transposase and inactivated derivatives, IS30 family
C7K38_07570	COG0745	RESPONSE REGULATOR receiver
C7K38_07575	COG5002	protein histidine kinase activity
C7K38_07575	COG3850	Histidine kinase
C7K38_07590	COG1368	sulfuric ester hydrolase activity
C7K38_07595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7K38_07600	COG0710	3-dehydroquinate dehydratase activity
C7K38_07605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7K38_07610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7K38_07615	COG0166	Belongs to the GPI family
C7K38_07645	COG0561	phosphatase activity
C7K38_07655	COG2252	PERMEase
C7K38_07665	COG0587	DNA-directed DNA polymerase activity
C7K38_07670	COG0205	6-phosphofructokinase activity
C7K38_07680	COG1399	metal-binding, possibly nucleic acid-binding protein
C7K38_07685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7K38_07690	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7K38_07695	COG0745	RESPONSE REGULATOR receiver
C7K38_07700	COG5002	protein histidine kinase activity
C7K38_07785	COG2826	transposase and inactivated derivatives, IS30 family
C7K38_07800	COG5504	Zn-dependent protease
C7K38_07815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_07820	COG3715	PTS system
C7K38_07825	COG3716	PTS system mannose fructose sorbose family IID component
C7K38_07830	COG0246	Mannitol dehydrogenase
C7K38_07835	COG0246	Mannitol dehydrogenase
C7K38_07840	COG3079	Belongs to the UPF0149 family
C7K38_07845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7K38_07850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7K38_07855	COG0251	oxidation-reduction process
C7K38_07860	COG1464	Belongs to the NlpA lipoprotein family
C7K38_07885	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K38_07885	COG3942	CHAP domain
C7K38_07900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_07900	COG1263	PTS System
C7K38_07905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7K38_07910	COG1349	DNA-binding transcription factor activity
C7K38_07915	COG1482	cell wall glycoprotein biosynthetic process
C7K38_07920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7K38_07925	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7K38_07930	COG0656	L-ascorbic acid biosynthetic process
C7K38_07940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7K38_07945	COG4221	oxidoreductase activity
C7K38_07960	COG0667	Aldo Keto reductase
C7K38_07975	COG0789	Transcriptional regulator
C7K38_07980	COG0656	L-ascorbic acid biosynthetic process
C7K38_07990	COG3425	synthase
C7K38_08010	COG0741	lytic transglycosylase activity
C7K38_08020	COG0358	DNA primase activity
C7K38_08025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7K38_08040	COG2996	Protein conserved in bacteria
C7K38_08045	COG0735	belongs to the Fur family
C7K38_08055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7K38_08060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7K38_08065	COG1187	pseudouridine synthase activity
C7K38_08070	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7K38_08080	COG0514	ATP-dependent DNA helicase (RecQ)
C7K38_08090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7K38_08100	COG0539	negative regulation of cytoplasmic translation
C7K38_08105	COG1160	GTP binding
C7K38_08110	COG0776	regulation of translation
C7K38_08115	COG1028	Short-chain dehydrogenase reductase Sdr
C7K38_08130	COG5582	Belongs to the UPF0302 family
C7K38_08135	COG1694	Mazg nucleotide pyrophosphohydrolase
C7K38_08140	COG0617	tRNA 3'-terminal CCA addition
C7K38_08160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7K38_08165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7K38_08175	COG4483	Protein conserved in bacteria
C7K38_08180	COG1940	carbohydrate kinase activity
C7K38_08185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7K38_08195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7K38_08200	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7K38_08220	COG1214	PFAM Peptidase M22, glycoprotease
C7K38_08235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7K38_08240	COG0052	Belongs to the universal ribosomal protein uS2 family
C7K38_08245	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7K38_08250	COG0528	UMP kinase activity
C7K38_08255	COG0233	cytoplasmic translational termination
C7K38_08260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7K38_08265	COG4589	Belongs to the CDS family
C7K38_08270	COG0750	zinc metalloprotease
C7K38_08275	COG0442	prolyl-tRNA aminoacylation
C7K38_08285	COG2137	regulation of response to DNA damage stimulus
C7K38_08290	COG1194	a g-specific adenine glycosylase
C7K38_08295	COG3557	Belongs to the UPF0374 family
C7K38_08305	COG1253	flavin adenine dinucleotide binding
C7K38_08310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7K38_08320	COG0542	response to heat
C7K38_08330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_08335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7K38_08350	COG0438	transferase activity, transferring glycosyl groups
C7K38_08355	COG2084	Dehydrogenase
C7K38_08360	COG4703	Protein of unknown function (DUF1797)
C7K38_08365	COG1846	Transcriptional regulator
C7K38_08370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7K38_08375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7K38_08380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7K38_08385	COG1028	Short-chain dehydrogenase reductase Sdr
C7K38_08390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7K38_08395	COG0511	ligase activity, forming carbon-carbon bonds
C7K38_08400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7K38_08405	COG0439	Biotin carboxylase
C7K38_08410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7K38_08415	COG0825	malonyl-CoA metabolic process
C7K38_08430	COG1607	acyl-coa hydrolase
C7K38_08450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K38_08455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7K38_08475	COG1263	PTS System
C7K38_08475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_08535	COG2610	gluconate transmembrane transporter activity
C7K38_08540	COG1929	Belongs to the glycerate kinase type-1 family
C7K38_08545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7K38_08565	COG4975	Glucose uptake
C7K38_08570	COG0673	inositol 2-dehydrogenase activity
C7K38_08575	COG1349	DNA-binding transcription factor activity
C7K38_08580	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7K38_08585	COG0673	inositol 2-dehydrogenase activity
C7K38_08590	COG1063	alcohol dehydrogenase
C7K38_08605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_08605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_08605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_08610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_08610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_08610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_08615	COG3684	Belongs to the aldolase LacD family
C7K38_08645	COG1129	ABC transporter
C7K38_08665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K38_08670	COG0277	FAD linked oxidase domain protein
C7K38_08695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7K38_08700	COG0366	Alpha amylase catalytic
C7K38_08745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7K38_08765	COG0511	ligase activity, forming carbon-carbon bonds
C7K38_08770	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C7K38_08780	COG2723	6-phospho-beta-galactosidase activity
C7K38_08785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K38_08795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K38_08795	COG1263	PTS System
C7K38_08800	COG1486	melibiose metabolic process
C7K38_08805	COG1737	Transcriptional regulator
C7K38_08825	COG0165	Argininosuccinate lyase
C7K38_08840	COG2096	Adenosyltransferase
C7K38_08855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7K38_08860	COG1534	Rna-binding protein
C7K38_08865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7K38_08870	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7K38_08875	COG0799	negative regulation of ribosome biogenesis
C7K38_08880	COG2226	methyltransferase
C7K38_08890	COG1323	Belongs to the UPF0348 family
C7K38_08895	COG0475	glutathione-regulated potassium exporter activity
C7K38_08895	COG0569	domain protein
C7K38_08905	COG3973	AAA domain
C7K38_08930	COG3189	MarR family transcriptional regulator
C7K38_08940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7K38_08945	COG0779	Required for maturation of 30S ribosomal subunits
C7K38_08950	COG0195	Participates in both transcription termination and antitermination
C7K38_08955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7K38_08970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7K38_08975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7K38_08980	COG0196	riboflavin kinase activity
C7K38_09020	COG1126	abc transporter atp-binding protein
C7K38_09030	COG0556	nucleotide-excision repair
C7K38_09035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7K38_09040	COG0471	metal ion transport
C7K38_09045	COG1660	Displays ATPase and GTPase activities
C7K38_09050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7K38_09055	COG1481	regulation of sporulation
C7K38_09065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7K38_09075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7K38_09095	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7K38_09100	COG1074	ATP-dependent DNA helicase activity
C7K38_09105	COG1733	regulation of RNA biosynthetic process
C7K38_09110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7K38_09115	COG0072	phenylalanine-tRNA ligase activity
C7K38_09115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7K38_09120	COG0180	Tryptophanyl-tRNA synthetase
C7K38_09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K38_09135	COG0765	amino acid transport
C7K38_09140	COG0765	amino acid transport
C7K38_09150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7K38_09155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7K38_09170	COG0668	transmembrane transport
C7K38_09175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7K38_09180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7K38_09195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7K38_09205	COG1234	tRNA 3'-trailer cleavage
C7K38_09210	COG0300	oxidoreductase activity
C7K38_09215	COG5416	Lipopolysaccharide assembly protein A domain
C7K38_09220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7K38_09220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7K38_09225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7K38_09235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7K38_09240	COG4224	UPF0291 protein
C7K38_09255	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K38_09255	COG1388	LysM domain
C7K38_09260	COG0735	belongs to the Fur family
C7K38_09265	COG3935	DnaD domain protein
C7K38_09275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7K38_09280	COG3331	DNA recombination
C7K38_09285	COG4474	Belongs to the UPF0398 family
C7K38_09290	COG3599	regulation of cell shape
C7K38_09300	COG0116	Belongs to the methyltransferase superfamily
C7K38_09320	COG0667	Aldo Keto reductase
C7K38_09350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7K38_09360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7K38_09365	COG2832	Protein of unknown function (DUF454)
C7K38_09375	COG1028	Short-chain dehydrogenase reductase Sdr
C7K38_09390	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7K38_09395	COG1418	mRNA catabolic process
C7K38_09405	COG0513	Belongs to the DEAD box helicase family
C7K38_09410	COG2153	protein acetylation
C7K38_09425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7K38_09435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7K38_09440	COG0328	RNA-DNA hybrid ribonuclease activity
C7K38_09450	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7K38_09460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7K38_09465	COG0564	pseudouridine synthase activity
C7K38_09470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7K38_09475	COG2233	PERMEase
C7K38_09480	COG0540	Belongs to the ATCase OTCase family
C7K38_09485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7K38_09490	COG0505	Belongs to the CarA family
C7K38_09495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7K38_09500	COG0284	orotidine-5'-phosphate decarboxylase activity
C7K38_09505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7K38_09530	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7K38_09540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7K38_09545	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7K38_09550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7K38_09555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7K38_09560	COG0287	Prephenate dehydrogenase
C7K38_09570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7K38_09575	COG0077	Prephenate dehydratase
C7K38_09580	COG1316	TRANSCRIPTIONal
C7K38_09585	COG1307	EDD domain protein, DegV family
C7K38_09590	COG2124	cytochrome p450
C7K38_09600	COG0454	-acetyltransferase
C7K38_09620	COG3859	Proton-coupled thiamine transporter YuaJ
C7K38_09625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7K38_09635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7K38_09640	COG0753	catalase activity
C7K38_09655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7K38_09670	COG1388	LysM domain
C7K38_09700	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7K38_09730	COG0167	dihydroorotate dehydrogenase activity
C7K38_09740	COG2207	Transcriptional regulator
C7K38_09740	COG3708	Transcriptional regulator
C7K38_09745	COG2151	metal-sulfur cluster biosynthetic enzyme
C7K38_09750	COG1199	ATP-dependent helicase activity
C7K38_09750	COG1199	ATP-dependent helicase activity
C7K38_09765	COG1968	undecaprenyl-diphosphatase activity
C7K38_09770	COG0268	Binds directly to 16S ribosomal RNA
C7K38_09775	COG1466	dna polymerase III delta subunit
C7K38_09780	COG2333	competence protein COMEC
C7K38_09780	COG0658	competence protein
C7K38_09785	COG2131	deaminase
C7K38_09790	COG1555	photosystem II stabilization
C7K38_09790	COG1596	polysaccharide export
C7K38_09795	COG0546	phosphoglycolate phosphatase activity
C7K38_09805	COG1126	abc transporter atp-binding protein
C7K38_09810	COG0765	amino acid transport
C7K38_09815	COG0519	Catalyzes the synthesis of GMP from XMP
C7K38_09825	COG0702	epimerase
C7K38_09835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7K38_09845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7K38_09850	COG0154	amidase activity
C7K38_09855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7K38_09860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7K38_09865	COG0210	DNA helicase
C7K38_09870	COG0038	chloride channel
C7K38_09875	COG1349	DNA-binding transcription factor activity
C7K38_09880	COG1105	Belongs to the carbohydrate kinase PfkB family
C7K38_09885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_09885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K38_09885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K38_09890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7K38_09895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7K38_09900	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7K38_09910	COG1714	RDD family
C7K38_09930	COG2365	Tyrosine phosphatase family
C7K38_09940	COG0402	S-adenosylhomocysteine deaminase activity
C7K38_09945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7K38_09950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7K38_09965	COG0481	GTPase activity
C7K38_09975	COG0628	permease
C7K38_09980	COG0542	response to heat
C7K38_09990	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7K38_09995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7K38_10000	COG2384	SAM-dependent methyltransferase
C7K38_10005	COG1484	DNA-dependent DNA replication
C7K38_10015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7K38_10020	COG0237	dephospho-CoA kinase activity
C7K38_10025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7K38_10030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7K38_10030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7K38_10050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7K38_10055	COG3091	SprT-like family
C7K38_10060	COG2183	response to ionizing radiation
C7K38_10085	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7K38_10090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7K38_10095	COG0742	ribosomal rna small subunit methyltransferase
C7K38_10100	COG4471	UPF0298 protein
C7K38_10110	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7K38_10115	COG0772	Belongs to the SEDS family
C7K38_10120	COG4838	Belongs to the UPF0358 family
C7K38_10130	COG0483	inositol monophosphate 1-phosphatase activity
C7K38_10135	COG4476	Belongs to the UPF0223 family
C7K38_10145	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7K38_10160	COG0561	phosphatase activity
C7K38_10180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7K38_10185	COG0516	GMP reductase activity
C7K38_10190	COG4989	oxidoreductase activity
C7K38_10195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7K38_10200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7K38_10205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7K38_10210	COG1966	Carbon starvation protein
C7K38_10215	COG3279	Response regulator of the LytR AlgR family
C7K38_10220	COG3275	phosphorelay sensor kinase activity
C7K38_10230	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K38_10235	COG1876	peptidase activity
C7K38_10265	COG0436	Aminotransferase
C7K38_10280	COG0667	Aldo Keto reductase
C7K38_10285	COG3103	Sh3 type 3 domain protein
C7K38_10285	COG0366	Alpha amylase catalytic
C7K38_10290	COG0058	SHG alpha-glucan phosphorylase activity
C7K38_10300	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7K38_10305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7K38_10315	COG1227	inorganic diphosphatase activity
C7K38_10320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7K38_10330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7K38_10335	COG0187	DNA topoisomerase II activity
C7K38_10340	COG1832	CoA-binding protein
C7K38_10345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7K38_10355	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7K38_10360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7K38_10365	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7K38_10375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7K38_10380	COG0758	DNA mediated transformation
C7K38_10385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7K38_10395	COG0681	Belongs to the peptidase S26 family
C7K38_10400	COG0793	Belongs to the peptidase S41A family
C7K38_10400	COG3409	Peptidoglycan-binding domain 1 protein
C7K38_10405	COG4479	Belongs to the UPF0346 family
C7K38_10415	COG4698	Protein conserved in bacteria
C7K38_10420	COG2755	lipolytic protein G-D-S-L family
C7K38_10425	COG1307	EDD domain protein, DegV family
C7K38_10430	COG0371	Dehydrogenase
C7K38_10435	COG1272	protein, Hemolysin III
C7K38_10450	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7K38_10455	COG0488	(ABC) transporter
C7K38_10460	COG0768	penicillin binding
C7K38_10475	COG1316	TRANSCRIPTIONal
C7K38_10480	COG1682	transport, permease protein
C7K38_10485	COG1134	teichoic acid transport
C7K38_10490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7K38_10505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7K38_10515	COG2246	polysaccharide biosynthetic process
C7K38_10530	COG0463	Glycosyl transferase, family 2
C7K38_10535	COG1368	sulfuric ester hydrolase activity
C7K38_10540	COG4841	protein insertion into membrane
C7K38_10545	COG0569	domain protein
C7K38_10550	COG2197	response regulator
C7K38_10555	COG4585	Histidine kinase
C7K38_10565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7K38_10570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7K38_10590	COG2826	transposase and inactivated derivatives, IS30 family
C7K38_10595	COG0463	Glycosyl transferase, family 2
C7K38_10595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7K38_10600	COG0584	glycerophosphoryl diester phosphodiesterase
C7K38_10605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7K38_10625	COG0017	Asparaginyl-tRNA synthetase
C7K38_10630	COG0436	Aminotransferase
C7K38_10640	COG1199	ATP-dependent helicase activity
C7K38_10640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7K38_10645	COG1278	Cold shock
C7K38_10655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7K38_10660	COG2217	Heavy metal translocating P-type atpase
C7K38_10680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7K38_10740	COG2176	DNA-directed DNA polymerase activity
C7K38_10745	COG1518	maintenance of DNA repeat elements
C7K38_10760	COG1857	crispr-associated protein
C7K38_10825	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7K38_10840	COG0513	Belongs to the DEAD box helicase family
C7K38_10845	COG0673	inositol 2-dehydrogenase activity
C7K38_10855	COG1686	Belongs to the peptidase S11 family
C7K38_10885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7K38_10895	COG1254	Belongs to the acylphosphatase family
C7K38_10910	COG0751	glycine-tRNA ligase activity
C7K38_10915	COG0752	glycyl-tRNA synthetase alpha subunit
C7K38_10920	COG1381	Involved in DNA repair and RecF pathway recombination
C7K38_10925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7K38_10935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7K38_10945	COG1702	phosphate starvation-inducible protein PhoH
C7K38_10950	COG1610	YqeY-like protein
C7K38_10955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7K38_10965	COG0735	belongs to the Fur family
C7K38_10970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7K38_10975	COG0083	homoserine kinase activity
C7K38_10980	COG0460	homoserine dehydrogenase
C7K38_10985	COG0640	Transcriptional regulator
C7K38_10990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7K38_10995	COG2723	6-phospho-beta-galactosidase activity
C7K38_11000	COG0561	phosphatase activity
C7K38_11010	COG1737	Transcriptional regulator
C7K38_11015	COG3344	reverse transcriptase
C7K38_11020	COG3763	UPF0154 protein
C7K38_11025	COG0656	L-ascorbic acid biosynthetic process
C7K38_11030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7K38_11040	COG3344	reverse transcriptase
C7K38_11045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7K38_11050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7K38_11085	COG0367	asparagine synthase
C7K38_11095	COG3328	transposase activity
C7K38_11100	COG3344	reverse transcriptase
C7K38_11105	COG1609	Transcriptional regulator
C7K38_11130	COG0783	Belongs to the Dps family
C7K38_11135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7K38_11185	COG0783	Belongs to the Dps family
C7K38_11205	COG2217	Heavy metal translocating P-type atpase
C7K38_11215	COG0582	viral genome integration into host DNA
C7K38_11230	COG3316	Transposase and inactivated derivatives
C7K38_11260	COG3385	transposase activity
C7K38_11275	COG3316	Transposase and inactivated derivatives
C7K38_11290	COG1131	(ABC) transporter
C7K38_11295	COG1131	(ABC) transporter
C7K38_11310	COG2217	Heavy metal translocating P-type atpase
C7K38_11330	COG0783	Belongs to the Dps family
C7K38_11380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7K38_11385	COG0783	Belongs to the Dps family
C7K38_11395	COG3316	Transposase and inactivated derivatives
C7K38_11400	COG0783	Belongs to the Dps family
C7K38_11410	COG1131	(ABC) transporter
C7K38_11415	COG1131	(ABC) transporter
C7K38_11430	COG3316	Transposase and inactivated derivatives
C7K38_11445	COG3385	transposase activity