locus-tag	class	description
GKE56_00010	ENOG4105DR5	peptidase
GKE56_00030	ENOG4105C7B	Threonine dehydratase
GKE56_00040	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GKE56_00085	ENOG4105C5B	carbamate kinase
GKE56_00120	ENOG4107U7N	hydantoinase B oxoprolinase
GKE56_00130	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
GKE56_00155	ENOG4105C2W	permease
GKE56_00165	ENOG4105G5A	Protein of unknown function (DUF2877)
GKE56_00170	ENOG4107R1Q	Membrane protein FdrA
GKE56_00175	ENOG4107REC	cytoplasmic protein
GKE56_00180	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GKE56_00190	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GKE56_00205	ENOG4105E9K	Isocitrate dehydrogenase
GKE56_00225	ENOG4108QV3	biosynthesis protein
GKE56_00235	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GKE56_00245	ENOG4105MVE	transcriptional regulator
GKE56_00250	ENOG4105C31	Tryptophanyl-tRNA synthetase
GKE56_00265	ENOG4105DZ1	carboxypeptidase
GKE56_00270	ENOG4105E33	succinate dehydrogenase
GKE56_00300	ENOG4105DIM	ABC transporter
GKE56_00320	ENOG4107RM1	amidohydrolase
GKE56_00325	ENOG4105DIH	basic membrane
GKE56_00330	ENOG4108JQ9	ABC transporter
GKE56_00360	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_00365	ENOG4105BZU	Histidine kinase
GKE56_00375	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GKE56_00395	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKE56_00430	ENOG4105C26	Dehydrogenase
GKE56_00435	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GKE56_00440	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GKE56_00450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKE56_00480	ENOG4108JIK	carboxylase
GKE56_00485	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
GKE56_00490	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GKE56_00515	ENOG4105C1G	acyl-Coa dehydrogenase
GKE56_00520	ENOG4107QX3	carboxylase
GKE56_00525	ENOG4107WR6	Maf-like protein
GKE56_00550	ENOG4105D8K	carboxyl transferase
GKE56_00565	ENOG4105E39	Enoyl-CoA hydratase
GKE56_00570	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_00575	ENOG4105EB3	Histidine kinase
GKE56_00590	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GKE56_00595	ENOG4105K4P	CoA-binding domain protein
GKE56_00600	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKE56_00605	ENOG4105F0R	Cytidylyltransferase
GKE56_00615	ENOG4105D2T	synthase
GKE56_00620	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
GKE56_00625	ENOG4108S0S	Nucleotidyl transferase
GKE56_00630	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GKE56_00635	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKE56_00660	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GKE56_00665	ENOG410602S	Transferase
GKE56_00675	ENOG4108KGH	TRANSCRIPTIONal
GKE56_00685	ENOG4108PBI	Polysaccharide metabolism
GKE56_00710	ENOG410602S	Transferase
GKE56_00720	ENOG4105EY8	ABC transporter
GKE56_00745	ENOG4107QNJ	CoA-transferase subunit B
GKE56_00785	ENOG4105CKK	Glycosyl transferase, family 2
GKE56_00800	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GKE56_00815	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
GKE56_00820	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKE56_00845	ENOG4107QKV	phosphomannomutase
GKE56_00875	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GKE56_00885	ENOG4108U8T	Mannosyltransferase
GKE56_00890	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_00895	ENOG4105BZU	Histidine kinase
GKE56_00965	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
GKE56_00995	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKE56_01000	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
GKE56_01005	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_01010	ENOG4105T0Z	Conserved Protein
GKE56_01200	ENOG4105CS9	pantothenic acid kinase
GKE56_01210	ENOG4105C26	Dehydrogenase
GKE56_01220	ENOG4105P4J	Allophanate hydrolase, subunit 1
GKE56_01225	ENOG4105E7W	lamb ycsf family protein
GKE56_01240	ENOG4105C7I	Dehydrogenase
GKE56_01315	ENOG4105CHU	acetyl-coa acetyltransferase
GKE56_01320	ENOG4105DJT	lAO AO transport system ATPase
GKE56_01325	ENOG4105D9P	serine threonine protein kinase
GKE56_01355	ENOG4105D5P	Methylmalonyl-coA mutase
GKE56_01380	ENOG4105CPF	Cell wall formation (By similarity)
GKE56_01400	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GKE56_01410	ENOG4105CG3	alpha amylase, catalytic region
GKE56_01415	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
GKE56_01445	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKE56_01450	ENOG4105EVB	acetyltransferase
GKE56_01460	ENOG4105BZJ	Electron transfer flavoprotein
GKE56_01465	ENOG4105C10	Electron transfer flavoprotein
GKE56_01485	ENOG4108594	Permease of the drug metabolite transporter
GKE56_01490	ENOG4105CEY	Amp-dependent synthetase and ligase
GKE56_01495	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GKE56_01500	ENOG4105C6F	GntR Family Transcriptional Regulator
GKE56_01505	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GKE56_01510	ENOG4105C6Z	Gluconate
GKE56_01515	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GKE56_01520	ENOG4105CAK	Cell division ATP-binding protein ftsE
GKE56_01530	ENOG4105E4C	Lytic transglycosylase catalytic
GKE56_01535	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GKE56_01550	ENOG41067RQ	csbd family
GKE56_01555	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
GKE56_01560	ENOG4108RYK	Nad-dependent epimerase dehydratase
GKE56_01565	ENOG4105KVH	Transcriptional regulator
GKE56_01580	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GKE56_01615	ENOG41080RH	Thioredoxin
GKE56_01625	ENOG4105DEN	Luciferase family
GKE56_01635	ENOG4105C1J	atp-dependent rna helicase
GKE56_01640	ENOG4108UJU	UPF0301 protein
GKE56_01670	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GKE56_01695	ENOG4105CGH	5'-nucleotidase
GKE56_01705	ENOG4107QZF	nitrite reductase NADPH large subunit
GKE56_01710	ENOG4107QZF	nitrite reductase NADPH large subunit
GKE56_01720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GKE56_01725	ENOG4107QND	Nitrite extrusion protein
GKE56_01730	ENOG4108RWI	nicotinamidase
GKE56_01745	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GKE56_01755	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GKE56_01760	ENOG4108RQ5	Beta-lactamase domain-containing protein
GKE56_01765	ENOG4105C5X	domain protein
GKE56_01775	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GKE56_01780	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GKE56_01805	ENOG4108JJB	ABC transporter
GKE56_01815	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
GKE56_01860	ENOG4105CHP	RNA polymerase
GKE56_01915	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GKE56_01960	ENOG4107YH6	single-stranded DNA-binding protein
GKE56_01980	ENOG4105CHR	reductase
GKE56_01985	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GKE56_02000	ENOG4105MHT	Transcriptional regulator, ARSR family
GKE56_02035	ENOG4105C29	acyl-CoA thioesterase
GKE56_02040	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GKE56_02045	ENOG4108VW9	Membrane
GKE56_02055	ENOG4108YYH	Nadph-dependent fmn reductase
GKE56_02060	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKE56_02085	ENOG4105CG3	alpha amylase, catalytic region
GKE56_02095	ENOG4105D8X	mechanosensitive ion channel
GKE56_02105	ENOG4105MC2	DSBA oxidoreductase
GKE56_02110	ENOG4108YZG	isomerase
GKE56_02150	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GKE56_02160	ENOG4105ETE	Transcriptional regulator (LacI family
GKE56_02170	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKE56_02175	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKE56_02180	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GKE56_02195	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKE56_02230	ENOG4105PSQ	Acyl-transferase
GKE56_02240	ENOG4105CQB	FAD linked oxidase domain protein
GKE56_02250	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GKE56_02260	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GKE56_02265	ENOG4108VHT	MarR family transcriptional regulator
GKE56_02285	ENOG4105CJN	penicillin-binding protein
GKE56_02305	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GKE56_02310	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GKE56_02315	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
GKE56_02320	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GKE56_02350	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
GKE56_02360	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
GKE56_02375	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GKE56_02380	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GKE56_02385	ENOG4105CN5	Metallo-Beta-Lactamase
GKE56_02390	ENOG4105C9B	Cysteine desulfurase
GKE56_02400	ENOG4105C2C	drug resistance transporter, Bcr CflA
GKE56_02415	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GKE56_02425	ENOG4105CEV	competence damage-inducible protein
GKE56_02430	ENOG4105WBV	Transcriptional regulator
GKE56_02435	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
GKE56_02450	ENOG4105EA8	2-Nitropropane dioxygenase
GKE56_02455	ENOG4105CJ1	ABC, transporter
GKE56_02470	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GKE56_02475	ENOG4105KC9	Modulates RecA activity (By similarity)
GKE56_02480	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GKE56_02485	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKE56_02490	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GKE56_02495	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GKE56_02500	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GKE56_02510	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GKE56_02515	ENOG4105I4A	GCN5-related N-acetyltransferase
GKE56_02540	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GKE56_02550	ENOG4105F27	Major Facilitator
GKE56_02555	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GKE56_02565	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GKE56_02570	ENOG4105M2Z	protein tyrosine serine phosphatase
GKE56_02590	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
GKE56_02595	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKE56_02610	ENOG4105NAF	rna polymerase sigma factor
GKE56_02615	ENOG4107YU2	histidine triad (hIT) protein
GKE56_02625	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GKE56_02635	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GKE56_02650	ENOG4105K6H	D-cysteine desulfhydrase
GKE56_02655	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GKE56_02670	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
GKE56_02675	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GKE56_02690	ENOG4105CJ1	ABC, transporter
GKE56_02705	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GKE56_02720	ENOG4108M15	ABC transporter
GKE56_02725	ENOG4105KCT	ABC transporter
GKE56_02730	ENOG4105BZU	Histidine kinase
GKE56_02735	ENOG4108S01	response regulator
GKE56_02755	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GKE56_02760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKE56_02775	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GKE56_02790	ENOG4107UBR	Extracellular solute-binding protein family 3
GKE56_02795	ENOG4105CDA	abc transporter atp-binding protein
GKE56_02810	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
GKE56_02855	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GKE56_02875	ENOG4105CMR	udp-glucose 4-epimerase
GKE56_02880	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GKE56_02885	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GKE56_02915	ENOG4105EGD	dinuclear metal center protein, YbgI family
GKE56_02925	ENOG4105CVJ	phosphoglycerate mutase
GKE56_02945	ENOG4107XFJ	UPF0246 protein
GKE56_02950	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GKE56_03015	ENOG4107T8T	UPF0173 metal-dependent hydrolase
GKE56_03030	ENOG4105DFK	Polyphosphate glucokinase
GKE56_03050	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKE56_03055	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GKE56_03085	ENOG4105C5F	glutamine synthetase
GKE56_03090	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GKE56_03095	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GKE56_03100	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GKE56_03105	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GKE56_03115	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GKE56_03120	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GKE56_03140	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GKE56_03145	ENOG41084BS	50S ribosomal protein L35
GKE56_03150	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GKE56_03155	ENOG4108RWN	rrna methyltransferase
GKE56_03160	ENOG4105BZU	Histidine kinase
GKE56_03170	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GKE56_03175	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
GKE56_03180	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GKE56_03190	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
GKE56_03195	ENOG4105CAS	nag kinase
GKE56_03200	ENOG4105C8Y	Acetylornithine aminotransferase
GKE56_03205	ENOG4105DBV	ornithine carbamoyltransferase
GKE56_03210	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GKE56_03215	ENOG4105CH7	arginosuccinase
GKE56_03230	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GKE56_03240	ENOG4108VX5	3-methyladenine DNA glycosylase
GKE56_03245	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GKE56_03270	ENOG4105DSU	hydrolase
GKE56_03290	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GKE56_03295	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GKE56_03330	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GKE56_03345	ENOG4105K5B	UPF0225 protein
GKE56_03350	ENOG4105C9M	aspartyl-trna synthetase
GKE56_03390	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GKE56_03395	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GKE56_03400	ENOG4105HHA	aminodeoxychorismate lyase
GKE56_03405	ENOG4105E2X	shikimate dehydrogenase
GKE56_03415	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GKE56_03420	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GKE56_03425	ENOG4105D49	3-dehydroquinate synthase
GKE56_03430	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GKE56_03435	ENOG410803B	Involved in the transcription termination process (By similarity)
GKE56_03440	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GKE56_03450	ENOG4105CD3	dihydroorotase
GKE56_03460	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GKE56_03465	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GKE56_03470	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GKE56_03475	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GKE56_03480	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GKE56_03490	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GKE56_03495	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GKE56_03505	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GKE56_03515	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKE56_03540	ENOG4105DJV	ribulose-phosphate 3-epimerase
GKE56_03560	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GKE56_03565	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GKE56_03570	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
GKE56_03575	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GKE56_03595	ENOG4105CAT	Cytidine monophosphate kinase
GKE56_03600	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GKE56_03615	ENOG4105BZ1	(ABC) transporter
GKE56_03620	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GKE56_03640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GKE56_03645	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GKE56_03650	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GKE56_03690	ENOG4105KV4	Transcriptional regulator
GKE56_03695	ENOG41087EV	Hsp20/alpha crystallin family
GKE56_03700	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKE56_03750	ENOG4105D9P	serine threonine protein kinase
GKE56_03810	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
GKE56_03840	ENOG4105BZU	Histidine kinase
GKE56_03845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GKE56_03850	ENOG4105BZU	Histidine kinase
GKE56_03870	ENOG4105KA0	thioesterase Superfamily protein
GKE56_03895	ENOG4105C54	Major Facilitator superfamily
GKE56_03900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKE56_03905	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GKE56_03910	ENOG410905P	Pyridoxamine 5-phosphate
GKE56_03915	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GKE56_03920	ENOG4105VG5	Membrane
GKE56_03930	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GKE56_03975	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GKE56_03980	ENOG4108IV0	ABC, transporter
GKE56_03990	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GKE56_03995	ENOG4105C32	Amino acid ABC transporter (Permease)
GKE56_04015	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GKE56_04025	ENOG4105CIE	May be required for sporulation (By similarity)
GKE56_04035	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GKE56_04040	ENOG4105BZA	Phosphoglycerate kinase
GKE56_04045	ENOG4105CP7	Triose-phosphate isomerase
GKE56_04060	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
GKE56_04075	ENOG4107QYV	phosphohexose isomerase
GKE56_04080	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GKE56_04090	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GKE56_04120	ENOG4107SM8	Adenylate Guanylate cyclase
GKE56_04125	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_04150	ENOG4105C3K	feS assembly ATPase SufC
GKE56_04160	ENOG4108UNV	SUF system FeS assembly protein, NifU family
GKE56_04165	ENOG4105VG1	fes assembly suf system protein
GKE56_04195	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GKE56_04210	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GKE56_04220	ENOG4106YT9	Enoyl-CoA hydratase
GKE56_04235	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKE56_04250	ENOG4105CHR	reductase
GKE56_04270	ENOG4105DDG	Cyanophycinase
GKE56_04275	ENOG4105EAC	phosphoserine phosphatase
GKE56_04295	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GKE56_04300	ENOG4107QPH	glycogen) synthase
GKE56_04310	ENOG4105DKW	ABC transporter
GKE56_04355	ENOG4105DXB	Major Facilitator superfamily
GKE56_04370	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
GKE56_04375	ENOG4105DCF	alanine dehydrogenase
GKE56_04385	ENOG4108ZJ4	polysaccharide deacetylase
GKE56_04395	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GKE56_04415	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GKE56_04425	ENOG4105CPQ	Dehydrogenase
GKE56_04460	ENOG4107QKS	N-acylglucosamine 2-epimerase
GKE56_04465	ENOG4108HKT	sucrose-6-phosphate hydrolase
GKE56_04495	ENOG4105ETE	Transcriptional regulator (LacI family
GKE56_04515	ENOG4105DYW	oxidoreductase
GKE56_04520	ENOG4105BZU	Histidine kinase
GKE56_04535	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GKE56_04560	ENOG4105CPC	Aldo Keto reductase
GKE56_04565	ENOG4105DYW	oxidoreductase
GKE56_04570	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GKE56_04590	ENOG4105C8N	cysteinyl-tRNA synthetase
GKE56_04600	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
GKE56_04610	ENOG4105C3R	Methionine synthase
GKE56_04625	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
GKE56_04640	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKE56_04660	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GKE56_04665	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GKE56_04670	ENOG4105D3R	alkyl hydroperoxide reductase
GKE56_04690	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
GKE56_04750	ENOG4105HFS	5'-3' exonuclease
GKE56_04760	ENOG4108Z66	YbaK ebsC protein
GKE56_04770	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GKE56_04775	ENOG4105FRY	Dehydrogenase
GKE56_04785	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
GKE56_04790	ENOG4107CHF	5,6-aminomutase beta subunit
GKE56_04795	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
GKE56_04805	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GKE56_04815	ENOG4105Q70	
GKE56_04865	ENOG4105E1V	na solute symporter
GKE56_04885	ENOG4106178	UPF0339 protein
GKE56_04900	ENOG4105CUB	amino acid
GKE56_04915	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GKE56_04920	ENOG4105CPQ	Dehydrogenase
GKE56_04935	ENOG4108UKZ	OsmC family
GKE56_04945	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GKE56_04950	ENOG4108ZM9	phosphoglycerate mutase
GKE56_04970	ENOG4107RFY	SbcCD D subunit
GKE56_04975	ENOG4105EYH	Exonuclease
GKE56_04980	ENOG4105EYH	Exonuclease
GKE56_04985	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKE56_05080	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GKE56_05090	ENOG4105CAT	Cytidine monophosphate kinase
GKE56_05105	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GKE56_05110	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GKE56_05130	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
GKE56_05135	ENOG4105CUT	histidyl-tRNA synthetase
GKE56_05145	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GKE56_05155	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GKE56_05160	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GKE56_05165	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GKE56_05180	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GKE56_05185	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GKE56_05190	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GKE56_05195	ENOG4105CDY	transcriptional regulatory protein
GKE56_05200	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
GKE56_05210	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GKE56_05220	ENOG4105E2K	Glycosyl transferase (Group 1
GKE56_05225	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
GKE56_05240	ENOG4105C22	threonyL-tRNA synthetase
GKE56_05255	ENOG4105CHR	reductase
GKE56_05260	ENOG4105CHU	acetyl-coa acetyltransferase
GKE56_05275	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GKE56_05310	ENOG4105F0I	Aminotransferase
GKE56_05325	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKE56_05330	ENOG4108UZX	fmn reductase
GKE56_05340	ENOG4105KAF	membrAne
GKE56_05360	ENOG4108KN0	Choline kinase
GKE56_05365	ENOG4108VB1	regulatoR
GKE56_05410	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GKE56_05430	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKE56_05455	ENOG4105EIG	urea carboxylase-associated protein 1
GKE56_05465	ENOG4107VXZ	Hydrolase
GKE56_05470	ENOG4105CG3	alpha amylase, catalytic region
GKE56_05495	ENOG4105ETX	regulatoR
GKE56_05500	ENOG41062D9	Histidine kinase
GKE56_05505	ENOG4105EB3	Histidine kinase
GKE56_05510	ENOG4105ETX	regulatoR
GKE56_05515	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GKE56_05525	ENOG4105C1G	acyl-Coa dehydrogenase
GKE56_05545	ENOG4105BZU	Histidine kinase
GKE56_05565	ENOG4105I1K	ABC transporter
GKE56_05570	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
GKE56_05590	ENOG4105DET	Rhamnulokinase
GKE56_05595	ENOG4105ETE	Transcriptional regulator (LacI family
GKE56_05600	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GKE56_05605	ENOG4107QR9	Iron-sulfur cluster binding protein
GKE56_05610	ENOG41080R8	Conserved Protein
GKE56_05620	ENOG4107QNJ	CoA-transferase subunit B
GKE56_05630	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
GKE56_05640	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
GKE56_05645	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
GKE56_05655	ENOG4107HP6	Transcriptional regulator
GKE56_05665	ENOG4105CI2	imidazolone-5-propionate hydrolase
GKE56_05670	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKE56_05675	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKE56_05685	ENOG4107HP6	Transcriptional regulator
GKE56_05705	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GKE56_05715	ENOG4107RNG	ABC transporter
GKE56_05720	ENOG4105C2J	ABC transporter
GKE56_05740	ENOG4105E8R	UPF0173 metal-dependent hydrolase
GKE56_05755	ENOG4105CHR	reductase
GKE56_05770	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GKE56_05780	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GKE56_05785	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GKE56_05790	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GKE56_05835	ENOG4105D3W	isochorismatase
GKE56_05850	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
GKE56_05880	ENOG4105C0H	protease
GKE56_05895	ENOG4105CHP	RNA polymerase
GKE56_05930	ENOG4107TXC	Transcriptional regulator
GKE56_05945	ENOG4107QN2	dihydrolipoyl dehydrogenase
GKE56_05960	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKE56_05990	ENOG4105CSU	acyl-Coa dehydrogenase
GKE56_05995	ENOG4105CSR	polyphosphate kinase 2
GKE56_06020	ENOG4105E0X	reductase
GKE56_06030	ENOG4107JTW	chlorite dismutase
GKE56_06035	ENOG4105C1Q	protoporphyrinogen oxidase
GKE56_06045	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GKE56_06065	ENOG4105CHU	acetyl-coa acetyltransferase
GKE56_06075	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GKE56_06100	ENOG4107QM5	aconitate hydratase
GKE56_06110	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GKE56_06115	ENOG4105C0X	amino acid
GKE56_06120	ENOG4107VEG	TrkA-N domain protein
GKE56_06145	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GKE56_06165	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GKE56_06170	ENOG4105EN6	Membrane
GKE56_06180	ENOG4107W53	thymidine kinase
GKE56_06195	ENOG4105CD5	CoA-binding domain protein
GKE56_06200	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
GKE56_06205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKE56_06215	ENOG4107T3P	ABC, transporter
GKE56_06240	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GKE56_06245	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKE56_06265	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GKE56_06270	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GKE56_06290	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GKE56_06320	ENOG4105EAH	synthase
GKE56_06330	ENOG41068JE	domain protein
GKE56_06355	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
GKE56_06380	ENOG4105DKQ	ROK family
GKE56_06385	ENOG4105DKQ	ROK family
GKE56_06395	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
GKE56_06445	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GKE56_06455	ENOG4105CCU	oxidase (Subunit III)
GKE56_06465	ENOG4107EUI	c reductase, iron-sulfur
GKE56_06470	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GKE56_06495	ENOG4105MCD	Part of cytochrome c oxidase, its function is
GKE56_06505	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GKE56_06510	ENOG4107QI6	Cysteine desulfurase
GKE56_06515	ENOG4105VFE	sira family
GKE56_06520	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GKE56_06560	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GKE56_06565	ENOG4105EG6	Saccharopine dehydrogenase
GKE56_06595	ENOG4108JJB	ABC transporter
GKE56_06615	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GKE56_06620	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GKE56_06645	ENOG4105ECP	epimerase
GKE56_06650	ENOG4107QPV	Serine Threonine protein kinase
GKE56_06660	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GKE56_06665	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GKE56_06690	ENOG4105C5F	glutamine synthetase
GKE56_06700	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GKE56_06705	ENOG4105VEQ	Cold shock protein
GKE56_06720	ENOG4108Q50	Histidine kinase
GKE56_06735	ENOG4105C0B	DNA polymerase III (alpha subunit)
GKE56_06750	ENOG4105NHS	Transcriptional regulator, TraR DksA family
GKE56_06775	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GKE56_06780	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GKE56_06790	ENOG4105DFU	Cell wall formation (By similarity)
GKE56_06795	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GKE56_06805	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GKE56_06810	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GKE56_06820	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GKE56_06825	ENOG4105CJN	penicillin-binding protein
GKE56_06835	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GKE56_06840	ENOG4108V6E	Cell division protein mraZ
GKE56_06845	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKE56_06870	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKE56_06875	ENOG4105SHT	UspA domain-containing protein
GKE56_06880	ENOG4105DWV	Homoserine O-trans-acetylase
GKE56_06965	ENOG4107R13	MMPL domain protein
GKE56_07020	ENOG4108W5M	transcriptional regulator
GKE56_07040	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKE56_07045	ENOG4105C98	muts2 protein
GKE56_07055	ENOG4105CPC	Aldo Keto reductase
GKE56_07070	ENOG4105EYF	MMPL domain protein
GKE56_07095	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GKE56_07100	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GKE56_07110	ENOG4105EM7	Selenocysteine-specific translation elongation factor
GKE56_07125	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GKE56_07140	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GKE56_07150	ENOG4108Z7F	N-acetyltransferase
GKE56_07190	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GKE56_07200	ENOG4105BZM	domain protein
GKE56_07205	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GKE56_07210	ENOG4105EPR	degv family
GKE56_07215	ENOG4105C8T	Leucyl-tRNA synthetase
GKE56_07225	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GKE56_07260	ENOG4105C5Z	peptidase
GKE56_07280	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKE56_07290	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKE56_07295	ENOG41061H0	Monooxygenase
GKE56_07305	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
GKE56_07345	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
GKE56_07355	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GKE56_07410	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GKE56_07425	ENOG4105QE3	oxidoreductase
GKE56_07455	ENOG4107UB2	Alpha beta hydrolase fold
GKE56_07465	ENOG4105Y7M	Transcriptional regulator, TetR family
GKE56_07475	ENOG4105CVJ	phosphoglycerate mutase
GKE56_07485	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GKE56_07500	ENOG4108KQJ	Type 11 methyltransferase
GKE56_07505	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GKE56_07510	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GKE56_07515	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GKE56_07525	ENOG4105K46	50S ribosomal protein l27
GKE56_07530	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GKE56_07535	ENOG4105C03	ribonuclease
GKE56_07580	ENOG4108IQE	Amp-dependent synthetase and ligase
GKE56_07585	ENOG4105CNI	cell division protein FtsW
GKE56_07595	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GKE56_07600	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GKE56_07610	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GKE56_07625	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
GKE56_07640	ENOG4108MRH	transcriptional regulatory protein
GKE56_07665	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_07695	ENOG4105BZU	Histidine kinase
GKE56_07700	ENOG4108UXN	response regulator
GKE56_07705	ENOG4105BZU	Histidine kinase
GKE56_07720	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GKE56_07735	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GKE56_07760	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GKE56_07765	ENOG4105DZP	Membrane-associated zinc metalloprotease
GKE56_07770	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GKE56_07775	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GKE56_07790	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
GKE56_07805	ENOG4105F38	ABC transporter, permease
GKE56_07810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKE56_07820	ENOG4105C26	Dehydrogenase
GKE56_07830	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GKE56_07855	ENOG4105PMW	Domain of unknown function (DUF1990)
GKE56_07870	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKE56_07875	ENOG4105KNE	Phosphatidate cytidylyltransferase
GKE56_07880	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GKE56_07885	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GKE56_07890	ENOG4105C9K	Endothelin-converting enzyme 1
GKE56_07895	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GKE56_07900	ENOG4105CE9	30S ribosomal protein S2
GKE56_07915	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKE56_07935	ENOG41080R2	UPF0102 protein
GKE56_07945	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GKE56_07950	ENOG4107QYR	Signal peptidase i
GKE56_07955	ENOG4107QYR	Signal peptidase i
GKE56_07960	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GKE56_07975	ENOG4105C4B	ABC transporter, permease
GKE56_07980	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GKE56_07985	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GKE56_07990	ENOG41082KU	UPF0109 protein
GKE56_07995	ENOG4105K5M	30s ribosomal protein S16
GKE56_08010	ENOG4108IJ6	ABC transporter
GKE56_08020	ENOG4108I5D	sulfate abc transporter
GKE56_08025	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GKE56_08045	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GKE56_08075	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GKE56_08085	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
GKE56_08090	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GKE56_08095	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GKE56_08100	ENOG41084BZ	50S ribosomal protein L32
GKE56_08115	ENOG4105EXC	Acyl-transferase
GKE56_08120	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GKE56_08135	ENOG4106H78	methyltransferase
GKE56_08150	ENOG4105DP4	dak2 domain fusion protein ylov
GKE56_08155	ENOG4105VB9	50S ribosomal protein l28
GKE56_08175	ENOG4105CPF	Cell wall formation (By similarity)
GKE56_08185	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GKE56_08190	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
GKE56_08195	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKE56_08200	ENOG4105K70	DNA-binding protein
GKE56_08205	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GKE56_08210	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GKE56_08215	ENOG41069M3	Transcriptional regulator
GKE56_08235	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKE56_08255	ENOG4105CDH	Citrulline--aspartate ligase
GKE56_08260	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GKE56_08265	ENOG4108Z86	Glutamine amidotransferase
GKE56_08270	ENOG4105CHR	reductase
GKE56_08275	ENOG4105C26	Dehydrogenase
GKE56_08280	ENOG4105CFQ	glutamine synthetase
GKE56_08285	ENOG4105C6F	GntR Family Transcriptional Regulator
GKE56_08290	ENOG4105CUB	amino acid
GKE56_08295	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GKE56_08300	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GKE56_08305	ENOG4108JQ1	Dehydrogenase
GKE56_08310	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GKE56_08325	ENOG4105C01	Dihydroxy-acid dehydratase
GKE56_08335	ENOG4105ECB	domain protein
GKE56_08370	ENOG4105D8V	Glucose sorbosone dehydrogenase
GKE56_08375	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKE56_08380	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKE56_08385	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKE56_08395	ENOG4105EE1	crotonyl-CoA reductase
GKE56_08410	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GKE56_08420	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
GKE56_08425	ENOG4108Z6Z	Transcriptional regulator
GKE56_08430	ENOG4105CPC	Aldo Keto reductase
GKE56_08435	ENOG4105RFZ	Methylmalonyl-coA mutase
GKE56_08445	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKE56_08460	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GKE56_08465	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GKE56_08470	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GKE56_08475	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GKE56_08480	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GKE56_08485	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GKE56_08490	ENOG4106DE0	ATP synthase
GKE56_08495	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
GKE56_08515	ENOG4105ESV	Glycosyl transferase, family 4
GKE56_08520	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GKE56_08535	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKE56_08540	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GKE56_08545	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GKE56_08550	ENOG4105BZU	Histidine kinase
GKE56_08560	ENOG4107S6X	Glycosyl transferase, family 2
GKE56_08570	ENOG4108PYU	two-component system response regulator
GKE56_08580	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GKE56_08585	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GKE56_08590	ENOG4105D6E	homoserine dehydrogenase
GKE56_08595	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GKE56_08600	ENOG4105C75	arginyL-tRNA synthetase
GKE56_08605	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_08620	ENOG4105C37	(CBS) domain
GKE56_08635	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GKE56_08660	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GKE56_08670	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GKE56_08690	ENOG4105CAQ	asparagine synthetase
GKE56_08715	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GKE56_08750	ENOG4107QQG	Dehydrogenase
GKE56_08755	ENOG4108IAJ	Nad-dependent epimerase dehydratase
GKE56_08770	ENOG4105E5Q	amino acid AbC transporter
GKE56_08775	ENOG4105CDA	abc transporter atp-binding protein
GKE56_08800	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GKE56_08805	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GKE56_08820	ENOG4105EMN	RNA polymerase sigma factor
GKE56_08840	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKE56_08845	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKE56_08875	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GKE56_08880	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GKE56_08885	ENOG4108JQ7	(ABC) transporter
GKE56_08890	ENOG4105C3U	ABC transporter
GKE56_08895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKE56_08900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKE56_08905	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKE56_08915	ENOG4107TK4	histidinol-phosphate phosphatase
GKE56_08930	ENOG4105CEP	NADH dehydrogenase
GKE56_08935	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GKE56_08950	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GKE56_08955	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GKE56_08970	ENOG4107X2D	transcriptional regulator, merr family
GKE56_08995	ENOG4107S11	squalene-associated FAD-dependent desaturase
GKE56_09005	ENOG4105D81	ABC transporter, permease
GKE56_09010	ENOG4107TYH	extracellular solute-binding protein family 1
GKE56_09015	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKE56_09040	ENOG4105D7B	Flagellar biosynthesis protein flha
GKE56_09045	ENOG4105D00	flagellar biosynthetic protein flhB
GKE56_09055	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GKE56_09060	ENOG4105VS8	Flagellar biosynthetic protein fliq
GKE56_09065	ENOG4105CN7	Flagellar biosynthetic protein FliP
GKE56_09075	ENOG4105DD5	Flagellar motor switch protein
GKE56_09080	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GKE56_09090	ENOG4105ER2	Ompa motb domain protein
GKE56_09095	ENOG4105E14	MotA TolQ exbB proton channel
GKE56_09105	ENOG4105BZE	flagellar hook protein, FlgE
GKE56_09110	ENOG4105W00	Flagellar hook capping protein
GKE56_09120	ENOG4105E4C	Lytic transglycosylase catalytic
GKE56_09135	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GKE56_09140	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GKE56_09145	ENOG41084Q6	flagellar hook-basal body complex protein fliE
GKE56_09150	ENOG4108ZC9	flagellar basal-body rod protein flgc
GKE56_09155	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GKE56_09160	ENOG4105I03	Flagellin
GKE56_09165	ENOG4105E1Q	flagellar hook-associated protein
GKE56_09185	ENOG4105I03	Flagellin
GKE56_09190	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKE56_09205	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GKE56_09220	ENOG4105BZU	Histidine kinase
GKE56_09275	ENOG41089UC	methyltransferase, type 11
GKE56_09280	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GKE56_09290	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GKE56_09300	ENOG41080HT	Transcriptional regulator, arsr family
GKE56_09350	ENOG4105BZU	Histidine kinase
GKE56_09375	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_09385	ENOG4107ZHV	Transcriptional regulator
GKE56_09410	ENOG4108JNI	Alpha beta hydrolase
GKE56_09415	ENOG4108ESY	Metal dependent phosphohydrolase
GKE56_09505	ENOG4105D8D	Type III
GKE56_09510	ENOG4107QMH	DNA methylase
GKE56_09535	ENOG4105VT3	DNA binding domain protein, excisionase family
GKE56_09560	ENOG4105DJZ	UPF0182 protein
GKE56_09570	ENOG41063PX	domain protein
GKE56_09620	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKE56_09635	ENOG410905P	Pyridoxamine 5-phosphate
GKE56_09660	ENOG4107X59	exodeoxyribonuclease V beta
GKE56_09695	ENOG4105C1J	atp-dependent rna helicase
GKE56_09705	ENOG4105DQ4	alcohol dehydrogenase
GKE56_09710	ENOG4107QJE	Chromosome Partitioning Protein
GKE56_09720	ENOG41081FY	multiple antibiotic resistance (MarC)-related
GKE56_09735	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GKE56_09740	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GKE56_09760	ENOG4105C1G	acyl-Coa dehydrogenase
GKE56_09775	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
GKE56_09780	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GKE56_09790	ENOG4105CTK	cobaltochelatase, cobn subunit
GKE56_09810	ENOG4105D9G	High-affinity
GKE56_09820	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
GKE56_09830	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GKE56_09835	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GKE56_09845	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GKE56_09850	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GKE56_09880	ENOG4105CI0	Citrate lyase
GKE56_09890	ENOG4105CJW	magnesium transporter
GKE56_09905	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GKE56_09910	ENOG4105C0H	protease
GKE56_09920	ENOG4105DU6	RNA polymerase
GKE56_09935	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GKE56_09950	ENOG4108UKI	Enoyl-CoA hydratase
GKE56_09965	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GKE56_09985	ENOG4108URH	decarboxylase
GKE56_10020	ENOG4108Z4U	Ferredoxin
GKE56_10045	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
GKE56_10050	ENOG4108J59	Extracellular solute-binding protein, family 5
GKE56_10055	ENOG4105CI3	gtp-binding protein typa
GKE56_10060	ENOG4105M6F	mutator MutT protein
GKE56_10065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKE56_10075	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKE56_10080	ENOG4105C3U	ABC transporter
GKE56_10085	ENOG4108JQ7	(ABC) transporter
GKE56_10090	ENOG410842T	Pterin carbinolamine dehydratase
GKE56_10120	ENOG4105C3G	gtp-binding protein
GKE56_10130	ENOG4105E09	nadh pyrophosphatase
GKE56_10135	ENOG4105CGY	Dna recombination protein
GKE56_10140	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GKE56_10150	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GKE56_10165	ENOG4105D7K	pfkb domain protein
GKE56_10180	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GKE56_10185	ENOG4105D5U	fad dependent oxidoreductase
GKE56_10190	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GKE56_10195	ENOG4108UJD	30S ribosomal protein S9
GKE56_10200	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GKE56_10220	ENOG4105C5H	ABC transporter
GKE56_10230	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GKE56_10235	ENOG4108ZT0	50S ribosomal protein l17
GKE56_10240	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKE56_10245	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GKE56_10250	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GKE56_10255	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKE56_10260	ENOG41067V7	50S ribosomal protein L36
GKE56_10265	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GKE56_10275	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GKE56_10285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GKE56_10290	ENOG410849U	50S ribosomal protein L30
GKE56_10295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GKE56_10300	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GKE56_10305	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GKE56_10310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GKE56_10315	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GKE56_10320	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKE56_10325	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GKE56_10330	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GKE56_10335	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GKE56_10340	ENOG41082SA	50s ribosomal protein l29
GKE56_10345	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GKE56_10350	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GKE56_10360	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GKE56_10370	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GKE56_10375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GKE56_10380	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GKE56_10385	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GKE56_10390	ENOG4105DMF	Dehydrogenase
GKE56_10405	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GKE56_10410	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GKE56_10415	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKE56_10420	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKE56_10480	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GKE56_10495	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GKE56_10500	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GKE56_10535	ENOG4107R4N	Cell wall formation (By similarity)
GKE56_10545	ENOG410900P	UPF0336 protein
GKE56_10550	ENOG4105WDJ	50S ribosomal protein L33
GKE56_10565	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GKE56_10585	ENOG410838B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GKE56_10600	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GKE56_10610	ENOG4105CGD	Nad-dependent epimerase dehydratase
GKE56_10620	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
GKE56_10665	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_10680	ENOG4108VPT	UPF0234 protein
GKE56_10685	ENOG4107TPY	serine threonine protein kinase
GKE56_10695	ENOG4108VQR	secreted hydrolase
GKE56_10700	ENOG4105D0M	Protease HtpX homolog
GKE56_10705	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10710	ENOG4105C8S	subunit m
GKE56_10715	ENOG4105D65	subunit l
GKE56_10720	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10730	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10735	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GKE56_10740	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKE56_10745	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10750	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKE56_10770	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GKE56_10775	ENOG4105DQU	oxidoreductase, subunit beta
GKE56_10790	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10805	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10810	ENOG4107UFS	subunit j
GKE56_10815	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10820	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GKE56_10825	ENOG4108IEH	NADH dehydrogenase subunit g
GKE56_10845	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKE56_10850	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_10865	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKE56_10870	ENOG4105E4F	Isochorismate synthase
GKE56_10875	ENOG4108HWW	ABC transporter
GKE56_10885	ENOG4105DFW	ABC transporter
GKE56_10890	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GKE56_10905	ENOG4105ETE	Transcriptional regulator (LacI family
GKE56_10910	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GKE56_10930	ENOG4107PP3	Acetylornithine deacetylase
GKE56_10955	ENOG4107TCW	O-succinylbenzoate synthase
GKE56_11005	ENOG4105CRE	cytochrome C
GKE56_11015	ENOG4107QIV	Cytochrome c biogenesis protein
GKE56_11025	ENOG4108RH7	phosphoglycerate mutase
GKE56_11030	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GKE56_11040	ENOG4108YYC	ycei family
GKE56_11045	ENOG4105D52	delta-aminolevulinic acid dehydratase
GKE56_11050	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GKE56_11060	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GKE56_11065	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
GKE56_11110	ENOG4107ZYR	domain protein
GKE56_11125	ENOG4105II7	pyrroline-5-carboxylate reductase
GKE56_11140	ENOG4105CIG	ABC transporter
GKE56_11155	ENOG4107YCR	Transcriptional regulator, ARSR family
GKE56_11160	ENOG4105U5Y	Transcriptional regulator
GKE56_11165	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
GKE56_11170	ENOG4107R33	ppx gppa phosphatase
GKE56_11175	ENOG4108JWX	
GKE56_11180	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GKE56_11190	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GKE56_11195	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
GKE56_11220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GKE56_11255	ENOG4105FDF	Could be involved in DNA repair (By similarity)
GKE56_11260	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
GKE56_11265	ENOG4105DQE	DNA ligase
GKE56_11290	ENOG4108IYU	L-aspartate oxidase
GKE56_11295	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GKE56_11300	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GKE56_11325	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKE56_11345	ENOG4105CRK	lysyL-tRNA synthetase
GKE56_11350	ENOG4105EUJ	GTP cyclohydrolase i
GKE56_11365	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GKE56_11380	ENOG4105F0N	pyrophosphate phospho-hydrolase
GKE56_11385	ENOG4105ZXU	NLP P60 protein
GKE56_11405	ENOG4105D74	hydrolase
GKE56_11425	ENOG4105GWZ	Roadblock lc7 family protein
GKE56_11460	ENOG4108KXV	response regulator
GKE56_11490	ENOG4107QRG	dna polymerase iii
GKE56_11500	ENOG4107TXC	Transcriptional regulator
GKE56_11515	ENOG4105C0Z	ABC transporter
GKE56_11520	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GKE56_11525	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GKE56_11570	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKE56_11580	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GKE56_11585	ENOG4105WN5	stage II sporulation protein
GKE56_11590	ENOG4108I5C	dEAD DEAH box helicase
GKE56_11645	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GKE56_11650	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GKE56_11660	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GKE56_11670	ENOG4105D74	hydrolase
GKE56_11680	ENOG4105P8F	nudix hydrolase
GKE56_11695	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GKE56_11730	ENOG4105N0U	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKE56_11735	ENOG4105BZ4	penicillin-binding protein
GKE56_11745	ENOG4105DIN	metallophosphoesterase
GKE56_11785	ENOG4105C5X	domain protein
GKE56_11830	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GKE56_11860	ENOG4105CFH	Aspartokinase
GKE56_11865	ENOG4105CJ1	ABC, transporter
GKE56_11880	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GKE56_11905	ENOG4105D7A	ATP-binding protein
GKE56_11935	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_11940	ENOG4105BZU	Histidine kinase
GKE56_11945	ENOG4105BZP	glycoside hydrolase 15-related
GKE56_11960	ENOG4105C1J	atp-dependent rna helicase
GKE56_11990	ENOG4105DQR	SNARE associated Golgi
GKE56_11995	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GKE56_12000	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GKE56_12015	ENOG4105CUB	amino acid
GKE56_12025	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GKE56_12040	ENOG4105EUB	pirin domain protein
GKE56_12045	ENOG4105CEY	Amp-dependent synthetase and ligase
GKE56_12055	ENOG4108KEZ	Dehydrogenase
GKE56_12070	ENOG41083YR	Protein CrcB homolog
GKE56_12075	ENOG4105WMR	Protein CrcB homolog
GKE56_12095	ENOG4107S9F	NmrA family
GKE56_12100	ENOG4105EMU	Dehydrogenase
GKE56_12110	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_12115	ENOG4105BZU	Histidine kinase
GKE56_12140	ENOG41080VW	acetyltransferase
GKE56_12150	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
GKE56_12160	ENOG4105SHT	UspA domain-containing protein
GKE56_12165	ENOG4105C2J	ABC transporter
GKE56_12170	ENOG4105CNN	ABC, transporter
GKE56_12175	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
GKE56_12180	ENOG4105ETE	Transcriptional regulator (LacI family
GKE56_12195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_12200	ENOG4105BZU	Histidine kinase
GKE56_12205	ENOG4105EDW	glycosyl transferase, family 39
GKE56_12205	ENOG4105EDW	glycosyl transferase, family 39
GKE56_12210	ENOG4105CND	Glycosyl transferase, family 2
GKE56_12225	ENOG4108RCF	TRANSCRIPTIONal
GKE56_12230	ENOG4105CJN	penicillin-binding protein
GKE56_12235	ENOG4105VEQ	Cold shock protein
GKE56_12245	ENOG4105EEI	dihydropteroate synthase
GKE56_12265	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GKE56_12270	ENOG4105C26	Dehydrogenase
GKE56_12275	ENOG4105CSW	GntR family transcriptional regulator
GKE56_12295	ENOG4105D7W	serine acetyltransferase
GKE56_12305	ENOG4105DF6	Fe-S oxidoreductase
GKE56_12310	ENOG4105PSQ	Acyl-transferase
GKE56_12330	ENOG4105E90	ABC transporter
GKE56_12335	ENOG4105E90	ABC transporter
GKE56_12340	ENOG4108IJ8	ABC transporter
GKE56_12345	ENOG4105C84	Histidine ammonia-lyase
GKE56_12355	ENOG4105DHP	deoxycytidine triphosphate deaminase
GKE56_12505	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
GKE56_12510	ENOG4105CPP	Dehydrogenase, E1 component
GKE56_12520	ENOG4105CPC	Aldo Keto reductase
GKE56_12525	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GKE56_12530	ENOG41082T9	Membrane
GKE56_12540	ENOG4108MRH	transcriptional regulatory protein
GKE56_12555	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GKE56_12575	ENOG4105CMR	udp-glucose 4-epimerase
GKE56_12585	ENOG4105CPC	Aldo Keto reductase
GKE56_12590	ENOG4107QTF	adenylosuccinate lyase
GKE56_12605	ENOG4105C3M	thioredoxin reductase
GKE56_12615	ENOG4108RWN	rrna methyltransferase
GKE56_12620	ENOG410667J	hydrolase
GKE56_12630	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GKE56_12635	ENOG410829K	Lysine exporter protein (Lyse ygga)
GKE56_12650	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GKE56_12660	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GKE56_12665	ENOG4105CQC	Prephenate dehydratase
GKE56_12715	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GKE56_12740	ENOG4105VFE	sira family
GKE56_12780	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GKE56_12790	ENOG4108Z4X	TRANSCRIPTIONal
GKE56_12830	ENOG4105HZM	Fha domain containing protein
GKE56_12845	ENOG4105CJN	penicillin-binding protein
GKE56_12850	ENOG4107TPY	serine threonine protein kinase
GKE56_12875	ENOG4108U4N	(sortase) family
GKE56_12885	ENOG4105ZJT	Cell division protein CrgA
GKE56_12925	ENOG4107YB1	Trehalose corynomycolyl transferase
GKE56_12930	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
GKE56_12940	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GKE56_12945	ENOG4106178	UPF0339 protein
GKE56_12960	ENOG41090CE	integral membrane protein
GKE56_12990	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKE56_12995	ENOG4105K7N	UPF0232 protein
GKE56_13000	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GKE56_13010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GKE56_13015	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GKE56_13020	ENOG41084CH	50S ribosomal protein l34
GKE56_13025	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GKE56_13030	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GKE56_13045	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GKE56_13050	ENOG4107QJE	Chromosome Partitioning Protein
GKE56_13060	ENOG4108E1C	hydrolase
GKE56_13065	ENOG4105K63	Thioredoxin
GKE56_13070	ENOG4105C3M	thioredoxin reductase
GKE56_13110	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKE56_13125	ENOG4105BZ4	penicillin-binding protein
GKE56_13135	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
GKE56_13150	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GKE56_13165	ENOG4105CK5	oxidoreductase
GKE56_13170	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
GKE56_13175	ENOG4105EDK	PfkB domain protein
GKE56_13185	ENOG4105DH8	myo-inositol catabolism
GKE56_13190	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
GKE56_13210	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GKE56_13215	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
GKE56_13270	ENOG4105CDA	abc transporter atp-binding protein
GKE56_13295	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GKE56_13305	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GKE56_13335	ENOG4105VPX	protein, conserved in bacteria
GKE56_13340	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GKE56_13355	ENOG4105CPQ	Dehydrogenase
GKE56_13360	ENOG4105DEI	Mannitol dehydrogenase
GKE56_13385	ENOG4105ETE	Transcriptional regulator (LacI family
GKE56_13390	ENOG4107T3P	ABC, transporter
GKE56_13400	ENOG4105DRS	transport system, permease
GKE56_13425	ENOG4105C2J	ABC transporter
GKE56_13430	ENOG4108HWW	ABC transporter
GKE56_13445	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
GKE56_13480	ENOG4105C84	Histidine ammonia-lyase
GKE56_13485	ENOG4105CGP	Urocanate hydratase
GKE56_13500	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GKE56_13515	ENOG4105CI2	imidazolone-5-propionate hydrolase
GKE56_13525	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
GKE56_13545	ENOG41084UD	rubredoxin
GKE56_13555	ENOG4106USH	transcriptional modulator of maze toxin, mazf
GKE56_13570	ENOG4105CFG	Acts as a chaperone (By similarity)
GKE56_13575	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKE56_13580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKE56_13585	ENOG4105KNI	merR family transcriptional Regulator
GKE56_13615	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GKE56_13640	ENOG4107UWP	Major facilitator superfamily MFS_1
GKE56_13660	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GKE56_13665	ENOG4108V0P	LemA family
GKE56_13730	ENOG4105C8V	SAICAR synthetase
GKE56_13740	ENOG410839H	phosphoribosylformylglycinamidine synthase
GKE56_13745	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GKE56_13750	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GKE56_13755	ENOG4105BZU	Histidine kinase
GKE56_13765	ENOG4105EE0	oxidoreductase
GKE56_13775	ENOG4105E2A	Dehydrogenase
GKE56_13830	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GKE56_13870	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GKE56_13885	ENOG4105EET	magnesium chelatase
GKE56_13890	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKE56_13895	ENOG4105ETS	cytosine purines uracil thiamine allantoin
GKE56_13930	ENOG4105DCG	PHP domain protein
GKE56_13940	ENOG4105E1F	short-chain dehydrogenase reductase
GKE56_13950	ENOG4105EUB	pirin domain protein
GKE56_13970	ENOG4105CZJ	Aldehyde dehydrogenase
GKE56_13985	ENOG4105CI2	imidazolone-5-propionate hydrolase
GKE56_13990	ENOG4105GAK	amidohydrolase 2
GKE56_13995	ENOG4105J4Q	Transcriptional regulator
GKE56_14000	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
GKE56_14015	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKE56_14020	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKE56_14025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKE56_14030	ENOG4105C3U	ABC transporter
GKE56_14040	ENOG4105C9B	Cysteine desulfurase
GKE56_14045	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GKE56_14050	ENOG41080QX	K07048 phosphotriesterase-related protein
GKE56_14085	ENOG4105RQI	acetone carboxylase gamma subunit
GKE56_14090	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
GKE56_14110	ENOG4107QNJ	CoA-transferase subunit B
GKE56_14115	ENOG4108QGH	periplasmic
GKE56_14120	ENOG4105C2J	ABC transporter
GKE56_14125	ENOG4105CNN	ABC, transporter
GKE56_14135	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKE56_14145	ENOG4107GJV	short-chain dehydrogenase reductase
GKE56_14150	ENOG4107SET	aldo keto reductase
GKE56_14155	ENOG4105XPP	Protein of unknown function (DUF1275)
GKE56_14160	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKE56_14170	ENOG4105CN8	Transcriptional regulator
GKE56_14175	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
GKE56_14215	ENOG4105K4H	Nlp p60 protein
GKE56_14335	ENOG4105CHR	reductase
GKE56_14345	ENOG4105CHR	reductase
GKE56_14355	ENOG4107RNG	ABC transporter
GKE56_14360	ENOG4105C2J	ABC transporter
GKE56_14365	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GKE56_14385	ENOG4108PVQ	transcriptional regulator
GKE56_14395	ENOG4105C1G	acyl-Coa dehydrogenase
GKE56_14400	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GKE56_14405	ENOG4108M9J	MaoC like domain protein
GKE56_14460	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_14505	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKE56_14525	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GKE56_14545	ENOG4105VTR	Integrase
GKE56_14640	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GKE56_14655	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
GKE56_14665	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GKE56_14670	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GKE56_14675	ENOG4107NHD	transcriptional regulator
GKE56_14695	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
GKE56_14710	ENOG4108KGH	TRANSCRIPTIONal
GKE56_14715	ENOG41090R7	Ferric uptake
GKE56_14720	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GKE56_14725	ENOG4107YJ4	chain length determinant protein
GKE56_14750	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GKE56_14775	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GKE56_14785	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GKE56_14795	ENOG4105BZU	Histidine kinase
GKE56_14815	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GKE56_14820	ENOG4105D9U	N-acetyltransferase
GKE56_14825	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GKE56_14830	ENOG4105C8N	cysteinyl-tRNA synthetase
GKE56_14835	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKE56_14860	ENOG4108IJ9	(ABC) transporter
GKE56_14875	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
GKE56_14880	ENOG41080XQ	Signal transduction protein with cbs domains
GKE56_14915	ENOG4108QV3	biosynthesis protein
GKE56_14985	ENOG4105F4R	Transcriptional regulator mode
GKE56_14990	ENOG4105DQE	DNA ligase
GKE56_15020	ENOG4105EXC	Acyl-transferase
GKE56_15035	ENOG4105CHR	reductase
GKE56_15070	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GKE56_15085	ENOG4105C3J	Cysteine desulfurase
GKE56_15105	ENOG4105KXX	peptidase s58 dmpa
GKE56_15110	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GKE56_15120	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKE56_15125	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKE56_15145	ENOG4107653	Transcriptional regulator
GKE56_15155	ENOG4105EEM	helicase
GKE56_15165	ENOG4105BZU	Histidine kinase
GKE56_15170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_15185	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GKE56_15200	ENOG4107WI4	Aldose-1-epimerase
GKE56_15210	ENOG4105VEQ	Cold shock protein
GKE56_15225	ENOG4105C7N	Xanthine uracil vitamin C permease
GKE56_15235	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GKE56_15280	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GKE56_15285	ENOG4105C01	Dihydroxy-acid dehydratase
GKE56_15290	ENOG4108UHU	Aldolase
GKE56_15310	ENOG4105K4H	Nlp p60 protein
GKE56_15320	ENOG4108UVJ	appr-1-p processing domain protein
GKE56_15325	ENOG4105PGM	cation diffusion facilitator family transporter
GKE56_15335	ENOG4105CG3	alpha amylase, catalytic region
GKE56_15340	ENOG4105K56	Transcriptional regulator
GKE56_15395	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GKE56_15485	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKE56_15510	ENOG4105DHQ	Histidine kinase
GKE56_15515	ENOG4105BZU	Histidine kinase
GKE56_15525	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GKE56_15540	ENOG4105C7K	acetolactate synthase
GKE56_15545	ENOG4105CBC	glutamate synthase
GKE56_15590	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GKE56_15600	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
GKE56_15610	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GKE56_15620	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
GKE56_15625	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GKE56_15635	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKE56_15640	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GKE56_15670	ENOG4108J6E	Pfam:Phage_integr_N
GKE56_15705	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
GKE56_15715	ENOG4108RTU	Aldolase
GKE56_15720	ENOG4105E2R	ROK family
GKE56_15725	ENOG4105CXK	mandelate racemase muconate lactonizing
GKE56_15730	ENOG4105E9Z	Nad-dependent epimerase dehydratase
GKE56_15735	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
GKE56_15740	ENOG4105I1K	ABC transporter
GKE56_15755	ENOG4105CJ1	ABC, transporter
GKE56_15770	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GKE56_15775	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GKE56_15785	ENOG4105E2R	ROK family
GKE56_15790	ENOG4107T3P	ABC, transporter
GKE56_15795	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GKE56_15805	ENOG4107YGS	glycoside hydrolase 15-related
GKE56_15830	ENOG4105CHR	reductase
GKE56_15865	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GKE56_15870	ENOG4105F8V	Hydrolase, tatD family
GKE56_15875	ENOG4106839	domain protein
GKE56_15880	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GKE56_15890	ENOG4105C5H	ABC transporter
GKE56_15895	ENOG4108ZT1	Transcriptional regulator
GKE56_15900	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GKE56_15905	ENOG41067SE	Tetr family transcriptional regulator
GKE56_15925	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GKE56_15930	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKE56_15945	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GKE56_15950	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GKE56_15960	ENOG4105D3Q	Sugar transferase
GKE56_15970	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GKE56_15995	ENOG4105E2K	Glycosyl transferase (Group 1
GKE56_16000	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKE56_16015	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GKE56_16060	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GKE56_16095	ENOG4105DD7	kinase (PfkB family
GKE56_16100	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
GKE56_16135	ENOG4107RN6	Monooxygenase
GKE56_16140	ENOG4105CHR	reductase
GKE56_16175	ENOG4105CHU	acetyl-coa acetyltransferase
GKE56_16195	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GKE56_16230	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GKE56_16240	ENOG4105T1M	mycothiol conjugate amidase mca
GKE56_16260	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GKE56_16265	ENOG4108IAB	Phoh family
GKE56_16280	ENOG4105CS9	pantothenic acid kinase
GKE56_16285	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GKE56_16290	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GKE56_16300	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GKE56_16310	ENOG4108097	ATP-binding protein
GKE56_16320	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GKE56_16325	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GKE56_16330	ENOG4105DU0	nucleoside hydrolase
GKE56_16335	ENOG4108RVA	ribokinase
GKE56_16370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKE56_16410	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GKE56_16455	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKE56_16465	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKE56_16495	ENOG4105VMP	Transcriptional regulator
GKE56_16510	ENOG4105CPQ	Dehydrogenase
GKE56_16525	ENOG4105IJJ	transcriptional regulator, crp fnr family
GKE56_16570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GKE56_16600	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GKE56_16605	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GKE56_16625	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKE56_16635	ENOG4107QVP	Dehydrogenase
GKE56_16660	ENOG4105BZ1	(ABC) transporter
GKE56_16665	ENOG4105BZ1	(ABC) transporter
GKE56_16725	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
GKE56_16755	ENOG4105WH1	Two component transcriptional regulator luxr family
GKE56_16770	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein