locus-tag	class	description
CFI11_00005	COG0424	maF-like protein
CFI11_00010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFI11_00015	COG0237	dephospho-CoA kinase activity
CFI11_00020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFI11_00025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFI11_00030	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFI11_00060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFI11_00065	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFI11_00080	COG1074	ATP-dependent DNA helicase activity
CFI11_00090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFI11_00095	COG3178	'Phosphotransferase
CFI11_00115	COG1999	signal sequence binding
CFI11_00120	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFI11_00130	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFI11_00145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFI11_00175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFI11_00180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFI11_00210	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CFI11_00210	COG0028	Belongs to the TPP enzyme family
CFI11_00270	COG1122	ATPase activity
CFI11_00280	COG1268	BioY protein
CFI11_00285	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_00295	COG2814	Major facilitator Superfamily
CFI11_00300	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_00305	COG0300	oxidoreductase activity
CFI11_00365	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_00385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_00390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFI11_00395	COG1136	(ABC) transporter
CFI11_00415	COG1960	acyl-CoA dehydrogenase activity
CFI11_00420	COG2091	lysine biosynthetic process via aminoadipic acid
CFI11_00425	COG3708	Transcriptional regulator
CFI11_00425	COG2207	Transcriptional regulator
CFI11_00430	COG1706	bacterial-type flagellum-dependent cell motility
CFI11_00450	COG1360	Flagellar Motor Protein
CFI11_00455	COG1338	Plays a role in the flagellum-specific transport system
CFI11_00460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFI11_00470	COG1766	The M ring may be actively involved in energy transduction
CFI11_00490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFI11_00505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFI11_00515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFI11_00530	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFI11_00540	COG4786	Flagellar basal body rod
CFI11_00545	COG4786	Flagellar basal body rod
CFI11_00550	COG1987	bacterial-type flagellum assembly
CFI11_00555	COG1677	Flagellar hook-basal body complex protein FliE
CFI11_00560	COG1558	bacterial-type flagellum-dependent cell motility
CFI11_00565	COG1815	bacterial-type flagellum-dependent cell motility
CFI11_00570	COG1157	protein secretion by the type III secretion system
CFI11_00580	COG5443	negative regulation of bacterial-type flagellum assembly
CFI11_00590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFI11_00610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFI11_00615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_00620	COG1177	transmembrane transport
CFI11_00625	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_00630	COG3842	ATPase activity
CFI11_00640	COG1802	Transcriptional regulator
CFI11_00650	COG3842	ATPase activity
CFI11_00660	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_00665	COG1177	transmembrane transport
CFI11_00675	COG2951	lytic endotransglycosylase activity
CFI11_00680	COG2378	regulation of single-species biofilm formation
CFI11_00700	COG2072	flavoprotein involved in K transport
CFI11_00730	COG1846	Transcriptional regulator
CFI11_00735	COG0745	RESPONSE REGULATOR receiver
CFI11_00740	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFI11_00745	COG1722	exodeoxyribonuclease VII activity
CFI11_00750	COG0142	geranyltranstransferase activity
CFI11_00755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFI11_00775	COG3396	Phenylacetate-CoA oxygenase
CFI11_00780	COG3460	Phenylacetate-CoA oxygenase
CFI11_00785	COG3396	Phenylacetate-CoA oxygenase
CFI11_00790	COG2151	metal-sulfur cluster biosynthetic enzyme
CFI11_00800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFI11_00820	COG1960	acyl-CoA dehydrogenase activity
CFI11_00825	COG0235	Class ii aldolase
CFI11_00825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CFI11_00845	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFI11_00850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFI11_00890	COG1132	(ABC) transporter
CFI11_00900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFI11_00905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFI11_00920	COG0697	spore germination
CFI11_00940	COG0560	Phosphoserine phosphatase
CFI11_00945	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFI11_00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFI11_00955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFI11_00960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFI11_00965	COG1063	alcohol dehydrogenase
CFI11_00970	COG0156	8-amino-7-oxononanoate synthase activity
CFI11_00975	COG1396	sequence-specific DNA binding
CFI11_00980	COG0183	Belongs to the thiolase family
CFI11_00990	COG2226	methyltransferase
CFI11_00995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFI11_01000	COG1024	Enoyl-CoA hydratase
CFI11_01005	COG0268	Binds directly to 16S ribosomal RNA
CFI11_01010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFI11_01015	COG0592	DNA-directed DNA polymerase activity
CFI11_01020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFI11_01025	COG0187	DNA topoisomerase II activity
CFI11_01050	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFI11_01060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFI11_01075	COG1335	isochorismatase
CFI11_01085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFI11_01095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFI11_01105	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFI11_01125	COG0514	ATP-dependent DNA helicase (RecQ)
CFI11_01130	COG3022	response to hydroperoxide
CFI11_01135	COG0784	Response regulator, receiver
CFI11_01135	COG2205	protein histidine kinase activity
CFI11_01135	COG5002	protein histidine kinase activity
CFI11_01140	COG2373	Large extracellular alpha-helical protein
CFI11_01145	COG4953	penicillin-binding protein 1C
CFI11_01175	COG0714	Associated with various cellular activities
CFI11_01205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFI11_01205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFI11_01235	COG1131	(ABC) transporter
CFI11_01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFI11_01255	COG0793	Belongs to the peptidase S41A family
CFI11_01265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_01275	COG0800	Aldolase
CFI11_01280	COG0129	dihydroxy-acid dehydratase activity
CFI11_01300	COG0129	dihydroxy-acid dehydratase activity
CFI11_01305	COG2274	protein secretion by the type I secretion system
CFI11_01310	COG1266	CAAX protease self-immunity
CFI11_01315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFI11_01320	COG0285	dihydrofolate synthase activity
CFI11_01325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFI11_01335	COG2423	ornithine cyclodeaminase activity
CFI11_01345	COG1671	Belongs to the UPF0178 family
CFI11_01350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFI11_01355	COG0679	Auxin Efflux Carrier
CFI11_01365	COG1309	transcriptional regulator
CFI11_01375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFI11_01380	COG2814	Major facilitator Superfamily
CFI11_01390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFI11_01400	COG2610	gluconate transmembrane transporter activity
CFI11_01415	COG0183	Belongs to the thiolase family
CFI11_01420	COG2050	protein possibly involved in aromatic compounds catabolism
CFI11_01425	COG2030	dehydratase
CFI11_01425	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_01430	COG3327	negative regulation of DNA-templated transcription, initiation
CFI11_01435	COG2172	sigma factor antagonist activity
CFI11_01465	COG0583	DNA-binding transcription factor activity
CFI11_01480	COG0583	DNA-binding transcription factor activity
CFI11_01485	COG0456	acetyltransferase
CFI11_01510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFI11_01515	COG0527	aspartate kinase activity
CFI11_01520	COG3473	Maleate cis-trans isomerase
CFI11_01540	COG2814	Major facilitator Superfamily
CFI11_01555	COG0791	NLP P60 protein
CFI11_01560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFI11_01570	COG0288	reversible hydration of carbon dioxide
CFI11_01600	COG3971	2-oxopent-4-enoate hydratase activity
CFI11_01635	COG2308	Evidence 4 Homologs of previously reported genes of
CFI11_01645	COG1305	Transglutaminase-like
CFI11_01660	COG0254	rRNA binding
CFI11_01665	COG0335	large ribosomal subunit rRNA binding
CFI11_01670	COG0336	Belongs to the RNA methyltransferase TrmD family
CFI11_01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFI11_01680	COG0778	Nitroreductase
CFI11_01685	COG0228	four-way junction DNA binding
CFI11_01720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFI11_01775	COG1802	Transcriptional regulator
CFI11_01780	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFI11_01790	COG3237	CsbD-like
CFI11_01805	COG0784	Response regulator, receiver
CFI11_01820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_01825	COG1295	ribonuclease BN
CFI11_01835	COG0400	carboxylic ester hydrolase activity
CFI11_01840	COG0346	lactoylglutathione lyase activity
CFI11_01850	COG2116	formate transmembrane transporter activity
CFI11_01865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFI11_01895	COG0583	DNA-binding transcription factor activity
CFI11_01905	COG0356	it plays a direct role in the translocation of protons across the membrane
CFI11_01910	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFI11_01915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFI11_01920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFI11_01925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFI11_01930	COG2186	Transcriptional regulator
CFI11_01955	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CFI11_01970	COG0435	Glutathione S-transferase
CFI11_01985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFI11_01990	COG0242	peptide deformylase activity
CFI11_01995	COG0242	peptide deformylase activity
CFI11_02000	COG0242	peptide deformylase activity
CFI11_02005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFI11_02015	COG0328	RNA-DNA hybrid ribonuclease activity
CFI11_02020	COG4106	trans-aconitate 2-methyltransferase activity
CFI11_02040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFI11_02050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFI11_02055	COG1758	RNA polymerase activity
CFI11_02060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFI11_02070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFI11_02075	COG1280	lysine exporter protein (LysE YggA)
CFI11_02085	COG0736	holo-[acyl-carrier-protein] synthase activity
CFI11_02090	COG0681	Belongs to the peptidase S26 family
CFI11_02095	COG0571	ribonuclease III activity
CFI11_02100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFI11_02110	COG1381	Involved in DNA repair and RecF pathway recombination
CFI11_02140	COG1648	precorrin-2 dehydrogenase activity
CFI11_02140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFI11_02145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFI11_02150	COG0243	molybdopterin cofactor binding
CFI11_02155	COG2146	nitrite reductase [NAD(P)H] activity
CFI11_02160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFI11_02165	COG1116	anion transmembrane transporter activity
CFI11_02170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_02175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFI11_02185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFI11_02185	COG1116	anion transmembrane transporter activity
CFI11_02190	COG3707	response regulator
CFI11_02195	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFI11_02200	COG0745	RESPONSE REGULATOR receiver
CFI11_02205	COG2205	protein histidine kinase activity
CFI11_02210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFI11_02215	COG1660	Displays ATPase and GTPase activities
CFI11_02225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFI11_02235	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_02265	COG0300	oxidoreductase activity
CFI11_02270	COG4991	sh3 domain protein
CFI11_02270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CFI11_02270	COG3103	Sh3 type 3 domain protein
CFI11_02275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFI11_02280	COG2124	cytochrome p450
CFI11_02290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFI11_02305	COG0110	maltose O-acetyltransferase activity
CFI11_02310	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFI11_02315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_02400	COG4974	Belongs to the 'phage' integrase family
CFI11_02460	COG0250	Participates in transcription elongation, termination and antitermination
CFI11_02465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFI11_02470	COG0081	regulation of translation
CFI11_02475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFI11_02480	COG0222	ribosome binding
CFI11_02485	COG0085	RNA polymerase activity
CFI11_02490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFI11_02495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_02505	COG3842	ATPase activity
CFI11_02510	COG0444	Belongs to the ABC transporter superfamily
CFI11_02550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFI11_02555	COG0049	tRNA binding
CFI11_02560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFI11_02570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFI11_02575	COG0051	transcription antitermination factor activity, RNA binding
CFI11_02580	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFI11_02585	COG0088	Forms part of the polypeptide exit tunnel
CFI11_02590	COG0089	rRNA binding
CFI11_02600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFI11_02605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFI11_02610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFI11_02615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFI11_02620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFI11_02630	COG0255	Belongs to the universal ribosomal protein uL29 family
CFI11_02635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFI11_02640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFI11_02645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFI11_02650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFI11_02655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFI11_02660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFI11_02665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFI11_02670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFI11_02675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFI11_02680	COG1841	ribosomal large subunit assembly
CFI11_02700	COG0200	Binds to the 23S rRNA
CFI11_02705	COG0201	protein transport
CFI11_02710	COG0563	adenylate kinase activity
CFI11_02715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFI11_02720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFI11_02725	COG0202	RNA polymerase activity
CFI11_02730	COG0203	ribosomal protein L17
CFI11_02735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFI11_02740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFI11_02745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFI11_02750	COG0564	pseudouridine synthase activity
CFI11_02755	COG0546	phosphoglycolate phosphatase activity
CFI11_02765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFI11_02770	COG4597	amino acid ABC transporter
CFI11_02775	COG0765	amino acid transport
CFI11_02780	COG1126	abc transporter atp-binding protein
CFI11_02800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFI11_02805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFI11_02815	COG0706	membrane insertase activity
CFI11_02820	COG2200	EAL domain
CFI11_02825	COG0037	tRNA processing
CFI11_02840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFI11_02845	COG0594	ribonuclease P activity
CFI11_02850	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFI11_02865	COG3852	Histidine kinase
CFI11_02880	COG0235	Class ii aldolase
CFI11_02885	COG3395	kinase activity
CFI11_02895	COG0473	3-isopropylmalate dehydrogenase activity
CFI11_02915	COG1802	Transcriptional regulator
CFI11_02960	COG0577	efflux transmembrane transporter activity
CFI11_02960	COG1136	(ABC) transporter
CFI11_02990	COG1175	transmembrane transport
CFI11_02995	COG0395	ABC-type sugar transport system, permease component
CFI11_03045	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFI11_03110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CFI11_03115	COG1177	transmembrane transport
CFI11_03120	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_03125	COG3842	ATPase activity
CFI11_03140	COG0583	DNA-binding transcription factor activity
CFI11_03150	COG0251	oxidation-reduction process
CFI11_03155	COG2072	flavoprotein involved in K transport
CFI11_03170	COG0583	DNA-binding transcription factor activity
CFI11_03175	COG0450	alkyl hydroperoxide reductase
CFI11_03190	COG2391	methyltransferase activity
CFI11_03220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_03240	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_03265	COG1477	protein flavinylation
CFI11_03270	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CFI11_03275	COG1805	sodium ion transport
CFI11_03285	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CFI11_03305	COG2084	Dehydrogenase
CFI11_03310	COG3386	PFAM SMP-30 Gluconolaconase
CFI11_03315	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_03320	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_03325	COG1129	ABC transporter
CFI11_03335	COG1609	Transcriptional regulator
CFI11_03360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFI11_03365	COG0772	Belongs to the SEDS family
CFI11_03370	COG0768	penicillin binding
CFI11_03415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_03435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFI11_03450	COG1959	2 iron, 2 sulfur cluster binding
CFI11_03460	COG4181	ATPase activity
CFI11_03475	COG1278	Cold shock
CFI11_03495	COG1376	ErfK ybiS ycfS ynhG family protein
CFI11_03515	COG0488	(ABC) transporter
CFI11_03520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFI11_03535	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CFI11_03560	COG1192	Involved in chromosome partitioning
CFI11_03580	COG0589	response to stress
CFI11_03590	COG0556	nucleotide-excision repair
CFI11_03605	COG0454	-acetyltransferase
CFI11_03620	COG1522	sequence-specific DNA binding
CFI11_03635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_03640	COG0747	negative chemotaxis
CFI11_03645	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_03650	COG0444	Belongs to the ABC transporter superfamily
CFI11_03655	COG4608	Belongs to the ABC transporter superfamily
CFI11_03660	COG0028	Belongs to the TPP enzyme family
CFI11_03675	COG0765	amino acid transport
CFI11_03680	COG0765	amino acid transport
CFI11_03690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFI11_03695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFI11_03700	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_03740	COG2010	Cytochrome c
CFI11_03745	COG0583	DNA-binding transcription factor activity
CFI11_03750	COG0348	domain, Protein
CFI11_03770	COG1686	Belongs to the peptidase S11 family
CFI11_03785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFI11_03800	COG0408	coproporphyrinogen oxidase activity
CFI11_03815	COG0181	hydroxymethylbilane synthase activity
CFI11_03820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFI11_03840	COG1648	precorrin-2 dehydrogenase activity
CFI11_03840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFI11_03845	COG1797	cobyrinic acid a,c-diamide synthase activity
CFI11_03850	COG2875	Belongs to the precorrin methyltransferase family
CFI11_03865	COG2099	Precorrin-6x reductase
CFI11_03925	COG0411	ABC transporter
CFI11_03935	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFI11_03940	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_03965	COG1178	ABC-type Fe3 transport system permease component
CFI11_03975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFI11_03980	COG0583	DNA-binding transcription factor activity
CFI11_03985	COG2267	carboxylic ester hydrolase activity
CFI11_03990	COG0747	negative chemotaxis
CFI11_03995	COG0601	transmembrane transport
CFI11_04000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_04010	COG4608	Belongs to the ABC transporter superfamily
CFI11_04015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFI11_04030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFI11_04040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFI11_04045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFI11_04055	COG0469	pyruvate kinase activity
CFI11_04080	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_04110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFI11_04125	COG0789	Transcriptional regulator
CFI11_04145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFI11_04150	COG0142	geranyltranstransferase activity
CFI11_04160	COG2264	protein methyltransferase activity
CFI11_04175	COG0583	DNA-binding transcription factor activity
CFI11_04195	COG2818	Glycosylase
CFI11_04220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFI11_04225	COG0165	Argininosuccinate lyase
CFI11_04245	COG0019	diaminopimelate decarboxylase activity
CFI11_04260	COG2884	Cell division ATP-binding protein ftsE
CFI11_04280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFI11_04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_04325	COG0045	succinate-CoA ligase (ADP-forming) activity
CFI11_04340	COG0039	L-malate dehydrogenase activity
CFI11_04355	COG2301	Belongs to the HpcH HpaI aldolase family
CFI11_04370	COG2030	dehydratase
CFI11_04400	COG0811	peptide transport
CFI11_04415	COG3720	iron ion transport
CFI11_04420	COG4558	Periplasmic binding protein
CFI11_04425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_04430	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFI11_04485	COG1522	sequence-specific DNA binding
CFI11_04505	COG0825	malonyl-CoA metabolic process
CFI11_04510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_04550	COG1960	acyl-CoA dehydrogenase activity
CFI11_04560	COG0583	DNA-binding transcription factor activity
CFI11_04575	COG0705	Rhomboid family
CFI11_04590	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_04595	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CFI11_04610	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_04620	COG4638	Rieske (2fe-2S)
CFI11_04645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFI11_04670	COG0444	Belongs to the ABC transporter superfamily
CFI11_04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_04680	COG0601	transmembrane transport
CFI11_04685	COG0747	negative chemotaxis
CFI11_04695	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CFI11_04700	COG1233	COG1233 Phytoene dehydrogenase and related
CFI11_04710	COG1984	allophanate hydrolase subunit 2
CFI11_04720	COG0439	Biotin carboxylase
CFI11_04730	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFI11_04735	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_04740	COG1129	ABC transporter
CFI11_04745	COG1879	ABC-type sugar transport system periplasmic component
CFI11_04755	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFI11_04760	COG0697	spore germination
CFI11_04785	COG0583	DNA-binding transcription factor activity
CFI11_04800	COG0601	transmembrane transport
CFI11_04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_04835	COG0297	glycogen (starch) synthase activity
CFI11_04840	COG0483	inositol monophosphate 1-phosphatase activity
CFI11_04865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_04865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_04875	COG1072	(Pantothenic acid kinase))
CFI11_04885	COG2217	Heavy metal translocating P-type atpase
CFI11_04920	COG1609	Transcriptional regulator
CFI11_04930	COG0673	inositol 2-dehydrogenase activity
CFI11_04945	COG0395	ABC-type sugar transport system, permease component
CFI11_04955	COG3842	ATPase activity
CFI11_04975	COG1070	Carbohydrate kinase
CFI11_04980	COG2115	Belongs to the xylose isomerase family
CFI11_04985	COG0747	negative chemotaxis
CFI11_05010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_05020	COG0444	Belongs to the ABC transporter superfamily
CFI11_05025	COG4608	Belongs to the ABC transporter superfamily
CFI11_05035	COG1414	Transcriptional regulator
CFI11_05065	COG3769	mannosylglycerate metabolic process
CFI11_05070	COG1215	transferase activity, transferring glycosyl groups
CFI11_05080	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFI11_05085	COG0830	nickel cation binding
CFI11_05090	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFI11_05105	COG0804	urea catabolic process
CFI11_05130	COG0832	Belongs to the urease beta subunit family
CFI11_05135	COG0831	urea catabolic process
CFI11_05140	COG0829	nickel cation binding
CFI11_05145	COG0519	Catalyzes the synthesis of GMP from XMP
CFI11_05145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFI11_05155	COG0174	glutamine synthetase
CFI11_05160	COG2205	protein histidine kinase activity
CFI11_05260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFI11_05265	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CFI11_05270	COG0535	radical SAM domain protein
CFI11_05275	COG0535	radical SAM domain protein
CFI11_05280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_05285	COG1414	Transcriptional regulator
CFI11_05305	COG5441	Belongs to the UPF0261 family
CFI11_05315	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFI11_05345	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_05345	COG1024	Enoyl-CoA hydratase
CFI11_05350	COG1960	acyl-CoA dehydrogenase activity
CFI11_05355	COG1960	acyl-CoA dehydrogenase activity
CFI11_05365	COG1024	Enoyl-CoA hydratase
CFI11_05370	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_05385	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CFI11_05395	COG3639	organic phosphonate transmembrane transporter activity
CFI11_05400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_05405	COG2188	Transcriptional regulator
CFI11_05410	COG3624	Phosphonate C-P lyase system protein PhnG
CFI11_05415	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFI11_05420	COG3626	phosphonate metabolism
CFI11_05425	COG3627	carbon phosphorus lyase activity
CFI11_05430	COG0596	Alpha beta hydrolase
CFI11_05430	COG2226	methyltransferase
CFI11_05430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFI11_05435	COG4107	phosphonate C-P lyase system protein PhnK
CFI11_05440	COG4778	phosphonate C-P lyase system protein PhnL
CFI11_05455	COG3454	Phosphonate metabolism
CFI11_05490	COG0588	phosphoglycerate mutase activity
CFI11_05495	COG0438	transferase activity, transferring glycosyl groups
CFI11_05510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFI11_05515	COG0668	transmembrane transport
CFI11_05525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_05530	COG0601	transmembrane transport
CFI11_05540	COG4172	Belongs to the ABC transporter superfamily
CFI11_05560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_05565	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_05575	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFI11_05580	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFI11_05600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFI11_05610	COG3002	Belongs to the UPF0753 family
CFI11_05615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFI11_05630	COG1522	sequence-specific DNA binding
CFI11_05635	COG4412	M6 family metalloprotease domain protein
CFI11_05635	COG1404	Belongs to the peptidase S8 family
CFI11_05655	COG1132	(ABC) transporter
CFI11_05660	COG0745	RESPONSE REGULATOR receiver
CFI11_05665	COG2205	protein histidine kinase activity
CFI11_05685	COG0154	amidase activity
CFI11_05690	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_05710	COG3485	protocatechuate 3,4-dioxygenase
CFI11_05715	COG3485	protocatechuate 3,4-dioxygenase
CFI11_05720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFI11_05725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFI11_05750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFI11_05755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFI11_05760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFI11_05785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFI11_05800	COG1702	phosphate starvation-inducible protein PhoH
CFI11_05805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFI11_05810	COG1253	flavin adenine dinucleotide binding
CFI11_05815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFI11_05820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFI11_05835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFI11_05845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFI11_05850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFI11_05860	COG0539	negative regulation of cytoplasmic translation
CFI11_05865	COG0776	regulation of translation
CFI11_05875	COG0135	phosphoribosylanthranilate isomerase activity
CFI11_05885	COG0133	tryptophan synthase activity
CFI11_05915	COG0193	aminoacyl-tRNA hydrolase activity
CFI11_05920	COG2329	Antibiotic biosynthesis monooxygenase
CFI11_05925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFI11_05940	COG1304	FMN binding
CFI11_05955	COG2030	dehydratase
CFI11_05960	COG0159	tryptophan synthase activity
CFI11_05965	COG0012	GTP binding
CFI11_05975	COG1136	(ABC) transporter
CFI11_05975	COG0577	efflux transmembrane transporter activity
CFI11_05985	COG1566	PFAM secretion protein HlyD family protein
CFI11_06080	COG0625	glutathione transferase activity
CFI11_06100	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_06105	COG0583	DNA-binding transcription factor activity
CFI11_06130	COG4974	Belongs to the 'phage' integrase family
CFI11_06165	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_06195	COG1309	transcriptional regulator
CFI11_06200	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_06205	COG0022	dehydrogenase e1 component
CFI11_06225	COG0583	DNA-binding transcription factor activity
CFI11_06245	COG0300	oxidoreductase activity
CFI11_06255	COG4974	Belongs to the 'phage' integrase family
CFI11_06285	COG0410	ABC transporter
CFI11_06290	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFI11_06330	COG2197	response regulator
CFI11_06340	COG0784	Response regulator, receiver
CFI11_06340	COG2198	Histidine kinase
CFI11_06340	COG5002	protein histidine kinase activity
CFI11_06370	COG0800	Aldolase
CFI11_06375	COG3734	2-keto-3-deoxy-galactonokinase
CFI11_06380	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_06390	COG0395	ABC-type sugar transport system, permease component
CFI11_06405	COG1414	Transcriptional regulator
CFI11_06415	COG4136	ATPase activity
CFI11_06420	COG4135	transport system, permease component
CFI11_06425	COG4134	Bacterial extracellular solute-binding protein
CFI11_06455	COG0395	ABC-type sugar transport system, permease component
CFI11_06460	COG3842	ATPase activity
CFI11_06480	COG4221	oxidoreductase activity
CFI11_06490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFI11_06505	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CFI11_06505	COG0662	Cupin 2, conserved barrel domain protein
CFI11_06540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFI11_06545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFI11_06550	COG0287	Prephenate dehydrogenase
CFI11_06565	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFI11_06590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFI11_06600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFI11_06605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFI11_06610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFI11_06615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFI11_06620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFI11_06655	COG2983	Belongs to the UPF0260 family
CFI11_06660	COG0196	riboflavin kinase activity
CFI11_06665	COG2030	dehydratase
CFI11_06675	COG4176	ABC-type proline glycine betaine transport system permease component
CFI11_06680	COG3448	diguanylate cyclase activity
CFI11_06680	COG4175	Glycine betaine
CFI11_06690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_06695	COG1609	Transcriptional regulator
CFI11_06700	COG1227	inorganic diphosphatase activity
CFI11_06725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFI11_06730	COG0459	protein refolding
CFI11_06750	COG3454	Phosphonate metabolism
CFI11_06755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFI11_06760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFI11_06770	COG0071	Belongs to the small heat shock protein (HSP20) family
CFI11_06790	COG0529	Catalyzes the synthesis of activated sulfate
CFI11_06790	COG2046	Belongs to the sulfate adenylyltransferase family
CFI11_06795	COG0492	ferredoxin-NADP+ reductase activity
CFI11_06800	COG1522	sequence-specific DNA binding
CFI11_06820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFI11_06840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFI11_06850	COG1435	thymidine kinase activity
CFI11_06855	COG0431	NADPH-dependent FMN reductase
CFI11_06880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFI11_06885	COG1032	radical SAM domain protein
CFI11_06890	COG1719	4-vinyl reductase, 4VR
CFI11_06895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFI11_06900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFI11_06935	COG0625	glutathione transferase activity
CFI11_06945	COG0778	Nitroreductase
CFI11_07000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFI11_07005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFI11_07020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFI11_07050	COG0842	Transport permease protein
CFI11_07080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_07090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFI11_07095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFI11_07100	COG0251	oxidation-reduction process
CFI11_07105	COG0583	DNA-binding transcription factor activity
CFI11_07110	COG0589	response to stress
CFI11_07125	COG2111	Na H antiporter
CFI11_07130	COG1006	Multisubunit Na H antiporter MnhC subunit
CFI11_07140	COG1863	multisubunit Na H antiporter MnhE subunit
CFI11_07145	COG2212	antiporter activity
CFI11_07150	COG1320	monovalent cation:proton antiporter activity
CFI11_07170	COG0625	glutathione transferase activity
CFI11_07175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFI11_07180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFI11_07190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFI11_07200	COG1643	Atp-dependent helicase
CFI11_07205	COG1703	isobutyryl-CoA mutase activity
CFI11_07210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_07240	COG1733	regulation of RNA biosynthetic process
CFI11_07255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFI11_07265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFI11_07270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFI11_07275	COG0583	DNA-binding transcription factor activity
CFI11_07285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CFI11_07305	COG0481	GTPase activity
CFI11_07320	COG1943	Transposase
CFI11_07340	COG0596	Alpha beta hydrolase
CFI11_07350	COG3739	integral membrane protein
CFI11_07355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFI11_07360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFI11_07365	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_07370	COG0154	amidase activity
CFI11_07380	COG0280	phosphate acetyltransferase
CFI11_07380	COG0281	malic enzyme
CFI11_07390	COG0295	cytidine deaminase activity
CFI11_07395	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFI11_07400	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFI11_07405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFI11_07420	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_07440	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_07440	COG1024	Enoyl-CoA hydratase
CFI11_07450	COG0183	Belongs to the thiolase family
CFI11_07460	COG0435	Glutathione S-transferase
CFI11_07475	COG1960	acyl-CoA dehydrogenase activity
CFI11_07480	COG0789	Transcriptional regulator
CFI11_07500	COG0534	Mate efflux family protein
CFI11_07505	COG0167	dihydroorotate dehydrogenase activity
CFI11_07520	COG0737	Belongs to the 5'-nucleotidase family
CFI11_07525	COG2135	peptidase activity
CFI11_07535	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFI11_07540	COG1984	allophanate hydrolase subunit 2
CFI11_07565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFI11_07570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_07595	COG3842	ATPase activity
CFI11_07610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFI11_07620	COG0395	ABC-type sugar transport system, permease component
CFI11_07625	COG1175	transmembrane transport
CFI11_07630	COG3842	ATPase activity
CFI11_07635	COG3842	ATPase activity
CFI11_07675	COG1132	(ABC) transporter
CFI11_07690	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_07715	COG4166	transmembrane transport
CFI11_07720	COG1929	Belongs to the glycerate kinase type-1 family
CFI11_07725	COG0471	metal ion transport
CFI11_07735	COG2379	hydroxypyruvate reductase
CFI11_07775	COG3853	Toxic anion resistance protein (TelA)
CFI11_07785	COG1187	pseudouridine synthase activity
CFI11_07790	COG0590	tRNA wobble adenosine to inosine editing
CFI11_07805	COG0385	Bile acid
CFI11_07810	COG0471	metal ion transport
CFI11_07810	COG0490	domain, Protein
CFI11_07815	COG0217	transcriptional regulatory protein
CFI11_07835	COG1132	(ABC) transporter
CFI11_07840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFI11_07850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFI11_07860	COG1024	Enoyl-CoA hydratase
CFI11_07865	COG0525	valine-tRNA ligase activity
CFI11_07890	COG0583	DNA-binding transcription factor activity
CFI11_07900	COG2130	NADP-dependent
CFI11_07905	COG2130	NADP-dependent
CFI11_07915	COG0483	inositol monophosphate 1-phosphatase activity
CFI11_07935	COG1522	sequence-specific DNA binding
CFI11_07950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFI11_07960	COG2353	YceI-like domain
CFI11_07965	COG0667	Aldo Keto reductase
CFI11_07975	COG3246	L-lysine catabolic process to acetate
CFI11_07980	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_07980	COG0824	Thioesterase
CFI11_08030	COG3706	GGDEF domain
CFI11_08030	COG0745	RESPONSE REGULATOR receiver
CFI11_08120	COG0297	glycogen (starch) synthase activity
CFI11_08195	COG4650	regulator
CFI11_08205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFI11_08210	COG1494	fructose-1,6-bisphosphatase
CFI11_08260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFI11_08270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_08275	COG4311	Sarcosine oxidase, delta subunit
CFI11_08280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_08280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFI11_08295	COG0358	DNA primase activity
CFI11_08300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFI11_08315	COG0432	Pfam Uncharacterised protein family UPF0047
CFI11_08325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_08325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_08355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFI11_08355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFI11_08360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFI11_08365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFI11_08385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFI11_08390	COG1304	FMN binding
CFI11_08395	COG0210	DNA helicase
CFI11_08410	COG2001	Belongs to the MraZ family
CFI11_08415	COG0275	rRNA processing
CFI11_08430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFI11_08435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFI11_08440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFI11_08450	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_08455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFI11_08460	COG2081	HI0933 family
CFI11_08470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFI11_08475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFI11_08485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFI11_08490	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFI11_08495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFI11_08500	COG0849	cell division
CFI11_08505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFI11_08510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CFI11_08515	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFI11_08520	COG0497	DNA recombination
CFI11_08590	COG0235	Class ii aldolase
CFI11_08600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFI11_08610	COG0596	Alpha beta hydrolase
CFI11_08620	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_08625	COG0308	aminopeptidase N
CFI11_08635	COG0415	Belongs to the DNA photolyase family
CFI11_08650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFI11_08660	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFI11_08665	COG2010	Cytochrome c
CFI11_08665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFI11_08680	COG3483	tryptophan 2,3-dioxygenase activity
CFI11_08700	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_08720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFI11_08745	COG2391	methyltransferase activity
CFI11_08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_08760	COG0601	transmembrane transport
CFI11_08770	COG4172	Belongs to the ABC transporter superfamily
CFI11_08780	COG1473	amidohydrolase
CFI11_08785	COG1473	amidohydrolase
CFI11_08795	COG1519	Transferase
CFI11_08800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFI11_08825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFI11_08830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_08835	COG0546	phosphoglycolate phosphatase activity
CFI11_08845	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_08850	COG1960	acyl-CoA dehydrogenase activity
CFI11_08855	COG3047	cAMP biosynthetic process
CFI11_08860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFI11_08880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFI11_08890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFI11_08900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFI11_08905	COG0649	NAD binding
CFI11_08915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFI11_08915	COG3743	rRNA binding
CFI11_08965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFI11_08975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFI11_08995	COG0713	ATP synthesis coupled electron transport
CFI11_09010	COG1007	ATP synthesis coupled electron transport
CFI11_09020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CFI11_09030	COG0513	Belongs to the DEAD box helicase family
CFI11_09060	COG0243	molybdopterin cofactor binding
CFI11_09070	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_09075	COG4335	DNA alkylation repair
CFI11_09080	COG3842	ATPase activity
CFI11_09095	COG2378	regulation of single-species biofilm formation
CFI11_09105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFI11_09110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFI11_09115	COG0805	protein transport
CFI11_09135	COG0739	heme binding
CFI11_09135	COG1388	LysM domain
CFI11_09140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFI11_09145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFI11_09150	COG4221	oxidoreductase activity
CFI11_09160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFI11_09185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_09195	COG1127	ABC transporter
CFI11_09200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFI11_09205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFI11_09215	COG0305	Participates in initiation and elongation during chromosome replication
CFI11_09220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFI11_09225	COG0418	dihydroorotase activity
CFI11_09265	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFI11_09290	COG2814	Major facilitator Superfamily
CFI11_09300	COG0367	asparagine synthase
CFI11_09310	COG0506	proline dehydrogenase activity
CFI11_09320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFI11_09330	COG2814	Major facilitator Superfamily
CFI11_09345	COG0175	sulfate reduction
CFI11_09350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFI11_09360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFI11_09360	COG1648	precorrin-2 dehydrogenase activity
CFI11_09365	COG1522	sequence-specific DNA binding
CFI11_09380	COG2204	response regulator
CFI11_09385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_09390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFI11_09395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_09400	COG0149	triose-phosphate isomerase activity
CFI11_09410	COG0316	Belongs to the HesB IscA family
CFI11_09420	COG2151	metal-sulfur cluster biosynthetic enzyme
CFI11_09425	COG0343	queuine tRNA-ribosyltransferase activity
CFI11_09430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFI11_09445	COG0406	alpha-ribazole phosphatase activity
CFI11_09450	COG1741	Belongs to the pirin family
CFI11_09490	COG0156	8-amino-7-oxononanoate synthase activity
CFI11_09500	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFI11_09525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFI11_09535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFI11_09540	COG0154	amidase activity
CFI11_09555	COG4638	Rieske (2fe-2S)
CFI11_09570	COG0440	acetolactate synthase activity
CFI11_09585	COG0028	Belongs to the TPP enzyme family
CFI11_09605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFI11_09615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_09625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFI11_09655	COG0346	lactoylglutathione lyase activity
CFI11_09660	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFI11_09760	COG4397	Mu-like prophage major head subunit gpT
CFI11_09805	COG4373	Mu-like prophage FluMu protein gp28
CFI11_09950	COG2801	Transposase and inactivated derivatives
CFI11_09990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFI11_10015	COG2124	cytochrome p450
CFI11_10050	COG3268	Saccharopine dehydrogenase
CFI11_10085	COG0542	response to heat
CFI11_10090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFI11_10095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFI11_10120	COG0316	Belongs to the HesB IscA family
CFI11_10125	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFI11_10130	COG0018	arginyl-trna synthetase
CFI11_10140	COG1472	Belongs to the glycosyl hydrolase 3 family
CFI11_10145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFI11_10150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFI11_10170	COG0717	Belongs to the dCTP deaminase family
CFI11_10185	COG0776	regulation of translation
CFI11_10190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFI11_10195	COG0416	fatty acid biosynthetic process
CFI11_10200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFI11_10245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFI11_10250	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFI11_10280	COG0148	phosphopyruvate hydratase activity
CFI11_10285	COG0697	spore germination
CFI11_10300	COG0513	Belongs to the DEAD box helicase family
CFI11_10315	COG0697	spore germination
CFI11_10320	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFI11_10345	COG3956	TIGRFAM MazG family protein
CFI11_10350	COG1473	amidohydrolase
CFI11_10355	COG0010	Belongs to the arginase family
CFI11_10375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFI11_10380	COG2890	protein-(glutamine-N5) methyltransferase activity
CFI11_10390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFI11_10395	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFI11_10405	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFI11_10420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFI11_10430	COG3577	Aspartyl protease
CFI11_10435	COG0488	(ABC) transporter
CFI11_10440	COG0105	UTP biosynthetic process
CFI11_10495	COG0215	cysteine-tRNA ligase activity
CFI11_10500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_10510	COG2814	Major facilitator Superfamily
CFI11_10525	COG1187	pseudouridine synthase activity
CFI11_10535	COG2423	ornithine cyclodeaminase activity
CFI11_10550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CFI11_10555	COG1238	metal cluster binding
CFI11_10570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_10580	COG4325	translation initiation factor activity
CFI11_10595	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_10600	COG4536	flavin adenine dinucleotide binding
CFI11_10605	COG4974	Belongs to the 'phage' integrase family
CFI11_10615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFI11_10620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFI11_10630	COG0629	single-stranded DNA binding
CFI11_10635	COG1196	nuclear chromosome segregation
CFI11_10635	COG0739	heme binding
CFI11_10635	COG0741	lytic transglycosylase activity
CFI11_10665	COG0601	transmembrane transport
CFI11_10680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFI11_10685	COG0528	UMP kinase activity
CFI11_10690	COG0233	cytoplasmic translational termination
CFI11_10695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFI11_10700	COG0575	Belongs to the CDS family
CFI11_10705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFI11_10710	COG0750	zinc metalloprotease
CFI11_10715	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFI11_10725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFI11_10730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFI11_10735	COG3494	Protein of unknown function (DUF1009)
CFI11_10740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFI11_10765	COG0482	sulfurtransferase activity
CFI11_10775	COG0745	RESPONSE REGULATOR receiver
CFI11_10780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFI11_10795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFI11_10800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFI11_10810	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFI11_10835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFI11_10840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFI11_10845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFI11_10855	COG1309	transcriptional regulator
CFI11_10860	COG2326	polyphosphate kinase activity
CFI11_10865	COG0596	Alpha beta hydrolase
CFI11_10870	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFI11_10890	COG0697	spore germination
CFI11_10895	COG0519	Catalyzes the synthesis of GMP from XMP
CFI11_10895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFI11_10900	COG5598	trimethylamine methyltransferase
CFI11_10920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFI11_10930	COG2867	negative regulation of translational initiation
CFI11_10940	COG1546	Belongs to the CinA family
CFI11_10945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFI11_10950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFI11_10950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFI11_10955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFI11_10960	COG3852	Histidine kinase
CFI11_10965	COG2204	response regulator
CFI11_10970	COG5000	phosphorelay sensor kinase activity
CFI11_10975	COG2204	response regulator
CFI11_10985	COG0569	domain protein
CFI11_10990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFI11_10995	COG1923	regulation of RNA biosynthetic process
CFI11_11000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFI11_11010	COG2084	Dehydrogenase
CFI11_11035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFI11_11045	COG2814	Major facilitator Superfamily
CFI11_11050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_11090	COG4166	transmembrane transport
CFI11_11095	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_11115	COG2313	pseudouridylate synthase activity
CFI11_11135	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFI11_11140	COG0352	thiamine-phosphate diphosphorylase activity
CFI11_11145	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_11155	COG1612	heme a metabolic process
CFI11_11160	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CFI11_11170	COG0583	DNA-binding transcription factor activity
CFI11_11180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFI11_11185	COG5425	PFAM Usg family protein
CFI11_11190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFI11_11200	COG0166	Belongs to the GPI family
CFI11_11205	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_11230	COG0516	GMP reductase activity
CFI11_11230	COG0517	IMP dehydrogenase activity
CFI11_11250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFI11_11255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFI11_11275	COG0538	isocitrate dehydrogenase activity
CFI11_11290	COG2945	thiolester hydrolase activity
CFI11_11300	COG1104	cysteine desulfurase activity
CFI11_11305	COG0719	Fe-S assembly protein
CFI11_11325	COG0396	ATPase activity
CFI11_11330	COG0719	Fe-S assembly protein
CFI11_11345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFI11_11355	COG0583	DNA-binding transcription factor activity
CFI11_11375	COG0596	Alpha beta hydrolase
CFI11_11380	COG0583	DNA-binding transcription factor activity
CFI11_11390	COG2948	multi-organism process
CFI11_11400	COG3701	Conjugal transfer protein
CFI11_11405	COG3846	protein secretion by the type IV secretion system
CFI11_11420	COG3451	type IV secretory pathway VirB4
CFI11_11435	COG4962	Type ii secretion system protein e
CFI11_11440	COG0583	DNA-binding transcription factor activity
CFI11_11475	COG0741	lytic transglycosylase activity
CFI11_11525	COG5489	Protein of unknown function (DUF736)
CFI11_11605	COG4974	Belongs to the 'phage' integrase family
CFI11_11610	COG3108	Peptidase M15
CFI11_11615	COG2989	Protein conserved in bacteria
CFI11_11620	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFI11_11625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFI11_11640	COG0433	COG0433 Predicted ATPase
CFI11_11680	COG0410	ABC transporter
CFI11_11695	COG2133	pyrroloquinoline quinone binding
CFI11_11710	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFI11_11720	COG1561	YicC-like family, N-terminal region
CFI11_11725	COG0194	GDP metabolic process
CFI11_11740	COG5002	protein histidine kinase activity
CFI11_11750	COG0573	inorganic phosphate transmembrane transporter activity
CFI11_11760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFI11_11765	COG0704	Plays a role in the regulation of phosphate uptake
CFI11_11770	COG0745	RESPONSE REGULATOR receiver
CFI11_11775	COG0583	DNA-binding transcription factor activity
CFI11_11780	COG1960	acyl-CoA dehydrogenase activity
CFI11_11790	COG0028	Belongs to the TPP enzyme family
CFI11_11795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_11810	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFI11_11815	COG2943	transferase activity, transferring hexosyl groups
CFI11_11830	COG0729	surface antigen
CFI11_11855	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_11860	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_11870	COG1946	Acyl-CoA thioesterase
CFI11_11875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFI11_11890	COG0625	glutathione transferase activity
CFI11_11930	COG0583	DNA-binding transcription factor activity
CFI11_11945	COG1280	lysine exporter protein (LysE YggA)
CFI11_11960	COG1131	(ABC) transporter
CFI11_12005	COG0183	Belongs to the thiolase family
CFI11_12010	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_12020	COG1960	acyl-CoA dehydrogenase activity
CFI11_12025	COG1960	acyl-CoA dehydrogenase activity
CFI11_12040	COG2130	NADP-dependent
CFI11_12050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFI11_12055	COG2771	luxR family
CFI11_12065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFI11_12070	COG0052	Belongs to the universal ribosomal protein uS2 family
CFI11_12095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFI11_12100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFI11_12105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFI11_12135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFI11_12140	COG3743	rRNA binding
CFI11_12140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFI11_12170	COG3811	Belongs to the UPF0386 family
CFI11_12175	COG0673	inositol 2-dehydrogenase activity
CFI11_12190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_12205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFI11_12215	COG0248	Ppx GppA phosphatase
CFI11_12220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFI11_12250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_12250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_12305	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_12320	COG1129	ABC transporter
CFI11_12330	COG1335	isochorismatase
CFI11_12350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_12355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_12360	COG1802	Transcriptional regulator
CFI11_12370	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_12385	COG0444	Belongs to the ABC transporter superfamily
CFI11_12400	COG0747	negative chemotaxis
CFI11_12445	COG0411	ABC transporter
CFI11_12450	COG0410	ABC transporter
CFI11_12455	COG1846	Transcriptional regulator
CFI11_12495	COG1309	transcriptional regulator
CFI11_12505	COG0287	Prephenate dehydrogenase
CFI11_12515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFI11_12530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFI11_12555	COG0435	Glutathione S-transferase
CFI11_12575	COG1177	transmembrane transport
CFI11_12580	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_12585	COG3842	ATPase activity
CFI11_12630	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_12640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFI11_12640	COG3264	Mechanosensitive ion channel
CFI11_12650	COG0494	nUDIX hydrolase
CFI11_12660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFI11_12665	COG0415	Belongs to the DNA photolyase family
CFI11_12670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFI11_12675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFI11_12680	COG0604	alcohol dehydrogenase
CFI11_12685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_12705	COG2186	Transcriptional regulator
CFI11_12750	COG0114	fumarate hydratase activity
CFI11_12770	COG3588	fructose-bisphosphate aldolase
CFI11_12775	COG2124	cytochrome p450
CFI11_12785	COG0785	Cytochrome C biogenesis protein
CFI11_12795	COG1530	ribonuclease E activity
CFI11_12810	COG2204	response regulator
CFI11_12820	COG0047	phosphoribosylformylglycinamidine synthase activity
CFI11_12825	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFI11_12830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFI11_12840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFI11_12840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFI11_12845	COG1410	methionine synthase
CFI11_12845	COG0646	methionine synthase
CFI11_12855	COG5012	cobalamin binding
CFI11_12865	COG2166	iron-sulfur cluster assembly
CFI11_12875	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFI11_12880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFI11_12885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFI11_12905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFI11_12920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFI11_12935	COG2169	Transcriptional regulator
CFI11_12935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFI11_12975	COG1192	Involved in chromosome partitioning
CFI11_13000	COG3772	lysozyme
CFI11_13120	COG4695	Portal protein
CFI11_13200	COG0582	viral genome integration into host DNA
CFI11_13270	COG1278	Cold shock
CFI11_13275	COG0259	pyridoxamine-phosphate oxidase activity
CFI11_13280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFI11_13285	COG1280	lysine exporter protein (LysE YggA)
CFI11_13290	COG1280	lysine exporter protein (LysE YggA)
CFI11_13295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFI11_13310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFI11_13330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFI11_13335	COG0134	indole-3-glycerol-phosphate synthase activity
CFI11_13340	COG0315	cyclic pyranopterin monophosphate synthase activity
CFI11_13345	COG0303	'Molybdopterin
CFI11_13350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFI11_13355	COG2333	competence protein COMEC
CFI11_13355	COG0658	competence protein
CFI11_13360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFI11_13365	COG0372	Belongs to the citrate synthase family
CFI11_13395	COG1024	Enoyl-CoA hydratase
CFI11_13400	COG3088	subunit of a heme lyase
CFI11_13405	COG1138	Cytochrome C-type biogenesis protein
CFI11_13420	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFI11_13425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFI11_13430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFI11_13460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFI11_13475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFI11_13490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFI11_13500	COG2354	Protein conserved in bacteria
CFI11_13510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFI11_13545	COG1960	acyl-CoA dehydrogenase activity
CFI11_13560	COG3287	FIST C domain
CFI11_13560	COG2200	EAL domain
CFI11_13560	COG2199	diguanylate cyclase activity
CFI11_13570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFI11_13580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFI11_13595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFI11_13605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFI11_13610	COG2833	Protein of unknown function (DUF455)
CFI11_13615	COG0739	heme binding
CFI11_13625	COG0477	Major facilitator Superfamily
CFI11_13635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFI11_13640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFI11_13645	COG0126	phosphoglycerate kinase activity
CFI11_13650	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CFI11_13655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFI11_13660	COG0022	dehydrogenase e1 component
CFI11_13660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_13665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_13750	COG4695	Portal protein
CFI11_13765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFI11_13770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFI11_13780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFI11_13790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFI11_13800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFI11_13805	COG3038	cytochrome b561
CFI11_13810	COG2353	YceI-like domain
CFI11_13820	COG0360	Binds together with S18 to 16S ribosomal RNA
CFI11_13825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFI11_13830	COG0359	binds to the 23S rRNA
CFI11_13835	COG3655	Transcriptional regulator
CFI11_13860	COG0737	Belongs to the 5'-nucleotidase family
CFI11_13865	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFI11_13885	COG1840	ABC-type Fe3 transport system, periplasmic component
CFI11_13945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFI11_13955	COG3609	addiction module antidote protein, CC2985 family
CFI11_14010	COG1686	Belongs to the peptidase S11 family
CFI11_14045	COG0513	Belongs to the DEAD box helicase family
CFI11_14050	COG1278	Cold shock
CFI11_14070	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFI11_14080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFI11_14185	COG0321	lipoyl(octanoyl) transferase activity
CFI11_14220	COG0505	Belongs to the CarA family
CFI11_14230	COG1802	Transcriptional regulator
CFI11_14260	COG1522	sequence-specific DNA binding
CFI11_14270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFI11_14280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFI11_14285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFI11_14290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFI11_14295	COG3409	Peptidoglycan-binding domain 1 protein
CFI11_14295	COG3773	Cell wall hydrolase
CFI11_14300	COG0574	Belongs to the PEP-utilizing enzyme family
CFI11_14300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFI11_14305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_14320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFI11_14325	COG0563	adenylate kinase activity
CFI11_14335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFI11_14340	COG0517	IMP dehydrogenase activity
CFI11_14340	COG0516	GMP reductase activity
CFI11_14350	COG5002	protein histidine kinase activity
CFI11_14350	COG2176	DNA-directed DNA polymerase activity
CFI11_14355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFI11_14370	COG0489	protein tyrosine kinase activity
CFI11_14410	COG0243	molybdopterin cofactor binding
CFI11_14410	COG3383	formate dehydrogenase (NAD+) activity
CFI11_14415	COG0437	4 iron, 4 sulfur cluster binding
CFI11_14440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_14445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_14470	COG1309	transcriptional regulator
CFI11_14525	COG2873	o-acetylhomoserine
CFI11_14530	COG2968	Membrane
CFI11_14560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFI11_14565	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFI11_14570	COG1329	Transcriptional regulator
CFI11_14610	COG1793	dna ligase
CFI11_14640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFI11_14645	COG0564	pseudouridine synthase activity
CFI11_14660	COG0456	acetyltransferase
CFI11_14685	COG0640	Transcriptional regulator
CFI11_14700	COG1126	abc transporter atp-binding protein
CFI11_14725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_14735	COG1414	Transcriptional regulator
CFI11_14745	COG0626	cystathionine gamma-synthase activity
CFI11_14755	COG0765	amino acid transport
CFI11_14760	COG4597	amino acid ABC transporter
CFI11_14765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFI11_14855	COG0131	Imidazoleglycerol-phosphate dehydratase
CFI11_14860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFI11_14885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFI11_14900	COG0107	imidazoleglycerol-phosphate synthase activity
CFI11_14920	COG1832	CoA-binding protein
CFI11_14935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFI11_14955	COG1175	transmembrane transport
CFI11_14985	COG1618	nucleotide phosphatase activity, acting on free nucleotides
CFI11_14985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFI11_14990	COG0303	'Molybdopterin
CFI11_15015	COG1858	cytochrome C peroxidase
CFI11_15030	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFI11_15035	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_15065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_15085	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_15095	COG3842	ATPase activity
CFI11_15130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_15135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_15140	COG1120	ATPase activity
CFI11_15145	COG1132	(ABC) transporter
CFI11_15150	COG4774	siderophore transport
CFI11_15165	COG1309	transcriptional regulator
CFI11_15170	COG2076	Multidrug Resistance protein
CFI11_15175	COG1846	Transcriptional regulator
CFI11_15185	COG0251	oxidation-reduction process
CFI11_15200	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFI11_15205	COG4149	molybdate abc transporter
CFI11_15210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFI11_15215	COG3750	Belongs to the UPF0335 family
CFI11_15245	COG5002	protein histidine kinase activity
CFI11_15255	COG0745	RESPONSE REGULATOR receiver
CFI11_15260	COG3800	Transcriptional regulator
CFI11_15260	COG1396	sequence-specific DNA binding
CFI11_15270	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFI11_15285	COG0410	ABC transporter
CFI11_15300	COG0511	ligase activity, forming carbon-carbon bonds
CFI11_15305	COG0439	Biotin carboxylase
CFI11_15310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFI11_15335	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFI11_15340	COG0740	serine-type endopeptidase activity
CFI11_15360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_15380	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_15390	COG0022	dehydrogenase e1 component
CFI11_15410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFI11_15415	COG0737	Belongs to the 5'-nucleotidase family
CFI11_15420	COG3258	Cytochrome c
CFI11_15445	COG0785	Cytochrome C biogenesis protein
CFI11_15465	COG2391	methyltransferase activity
CFI11_15475	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CFI11_15490	COG3246	L-lysine catabolic process to acetate
CFI11_15515	COG0477	Major facilitator Superfamily
CFI11_15535	COG1686	Belongs to the peptidase S11 family
CFI11_15540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFI11_15550	COG0084	hydrolase, TatD family'
CFI11_15555	COG1234	tRNA 3'-trailer cleavage
CFI11_15570	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CFI11_15580	COG1116	anion transmembrane transporter activity
CFI11_15585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_15590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFI11_15595	COG3604	Transcriptional regulator
CFI11_15605	COG1131	(ABC) transporter
CFI11_15695	COG0523	cobalamin synthesis protein
CFI11_15700	COG0523	cobalamin synthesis protein
CFI11_15740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFI11_15750	COG0589	response to stress
CFI11_15755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_15780	COG0747	negative chemotaxis
CFI11_15785	COG0601	transmembrane transport
CFI11_15795	COG0405	Gamma-glutamyltransferase
CFI11_15805	COG2186	Transcriptional regulator
CFI11_15820	COG4166	transmembrane transport
CFI11_15825	COG0601	transmembrane transport
CFI11_15830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_15840	COG1473	amidohydrolase
CFI11_15860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_15865	COG3608	succinylglutamate desuccinylase aspartoacylase
CFI11_15865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFI11_15895	COG5001	Diguanylate cyclase
CFI11_15895	COG3300	MHYT domain
CFI11_15920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_15955	COG2951	lytic endotransglycosylase activity
CFI11_15965	COG3209	COG3209 Rhs family protein
CFI11_15980	COG3501	Rhs element vgr protein
CFI11_15990	COG0673	inositol 2-dehydrogenase activity
CFI11_16010	COG0006	proline dipeptidase activity
CFI11_16040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFI11_16045	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFI11_16050	COG0751	glycine-tRNA ligase activity
CFI11_16060	COG0752	glycyl-tRNA synthetase alpha subunit
CFI11_16075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFI11_16095	COG1469	GTP cyclohydrolase I activity
CFI11_16110	COG0625	glutathione transferase activity
CFI11_16115	COG2917	probably involved in intracellular septation
CFI11_16125	COG0552	protein localization to endoplasmic reticulum
CFI11_16150	COG0151	Belongs to the GarS family
CFI11_16180	COG0330	HflC and HflK could
CFI11_16195	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFI11_16210	COG1760	l-serine dehydratase
CFI11_16235	COG0789	Transcriptional regulator
CFI11_16245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFI11_16250	COG2746	aminoglycoside 3-N-acetyltransferase activity
CFI11_16260	COG0189	ligase activity
CFI11_16285	COG0504	CTP synthase activity
CFI11_16330	COG4215	(ABC) transporter
CFI11_16335	COG4160	amino acid transport
CFI11_16340	COG0174	glutamine synthetase
CFI11_16345	COG0519	Catalyzes the synthesis of GMP from XMP
CFI11_16345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFI11_16350	COG0174	glutamine synthetase
CFI11_16355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_16360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFI11_16380	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFI11_16410	COG0640	Transcriptional regulator
CFI11_16435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFI11_16445	COG3220	belongs to the UPF0276 family
CFI11_16465	COG1393	Belongs to the ArsC family
CFI11_16470	COG1278	Cold shock
CFI11_16485	COG2124	cytochrome p450
CFI11_16490	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CFI11_16505	COG0346	lactoylglutathione lyase activity
CFI11_16515	COG1846	Transcriptional regulator
CFI11_16540	COG0534	Mate efflux family protein
CFI11_16545	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFI11_16560	COG0305	Participates in initiation and elongation during chromosome replication
CFI11_16565	COG0596	Alpha beta hydrolase
CFI11_16575	COG2268	Band 7 protein
CFI11_16590	COG0187	DNA topoisomerase II activity
CFI11_16620	COG2010	Cytochrome c
CFI11_16630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFI11_16635	COG1136	(ABC) transporter
CFI11_16660	COG0442	prolyl-tRNA aminoacylation
CFI11_16665	COG0628	permease
CFI11_16675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFI11_16685	COG0248	Ppx GppA phosphatase
CFI11_16700	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CFI11_16730	COG0439	Biotin carboxylase
CFI11_16765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFI11_16775	COG1396	sequence-specific DNA binding
CFI11_16775	COG3800	Transcriptional regulator
CFI11_16795	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_16800	COG3119	arylsulfatase activity
CFI11_16805	COG1309	transcriptional regulator
CFI11_16825	COG4175	Glycine betaine
CFI11_16850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFI11_16865	COG1492	cobalamin metabolic process
CFI11_16880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFI11_16920	COG2072	flavoprotein involved in K transport
CFI11_16935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFI11_16945	COG2986	histidine ammonia-lyase
CFI11_16950	COG1228	amidohydrolase
CFI11_16955	COG0471	metal ion transport
CFI11_16955	COG3273	potassium ion transport
CFI11_16965	COG1692	metallophosphoesterase
CFI11_16970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFI11_16975	COG2239	Acts as a magnesium transporter
CFI11_16980	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_17005	COG0583	DNA-binding transcription factor activity
CFI11_17015	COG0670	Belongs to the BI1 family
CFI11_17025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFI11_17055	COG0154	amidase activity
CFI11_17060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFI11_17065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFI11_17075	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFI11_17080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFI11_17120	COG0659	secondary active sulfate transmembrane transporter activity
CFI11_17125	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFI11_17130	COG1280	lysine exporter protein (LysE YggA)
CFI11_17135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFI11_17140	COG0277	FAD linked oxidase domain protein
CFI11_17155	COG0612	Peptidase, M16
CFI11_17175	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFI11_17180	COG0109	protoheme IX farnesyltransferase activity
CFI11_17190	COG0312	modulator of DNA gyrase
CFI11_17200	COG0758	DNA mediated transformation
CFI11_17205	COG1754	DNA topoisomerase type I activity
CFI11_17205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFI11_17215	COG3920	Histidine kinase
CFI11_17245	COG4964	Belongs to the GSP D family
CFI11_17300	COG1201	RNA secondary structure unwinding
CFI11_17315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFI11_17325	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CFI11_17335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFI11_17340	COG0037	tRNA processing
CFI11_17350	COG2885	chlorophyll binding
CFI11_17375	COG0824	Thioesterase
CFI11_17385	COG2255	four-way junction helicase activity
CFI11_17390	COG0632	four-way junction helicase activity
CFI11_17410	COG2264	protein methyltransferase activity
CFI11_17425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFI11_17435	COG4974	Belongs to the 'phage' integrase family
CFI11_17440	COG1183	phosphatidylcholine synthase activity
CFI11_17450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFI11_17460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFI11_17470	COG0492	ferredoxin-NADP+ reductase activity
CFI11_17470	COG3118	belongs to the thioredoxin family
CFI11_17475	COG3768	UPF0283 membrane protein
CFI11_17485	COG3106	COG3106 Predicted ATPase
CFI11_17490	COG0101	tRNA pseudouridine synthase activity
CFI11_17515	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFI11_17515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFI11_17520	COG0509	glycine decarboxylation via glycine cleavage system
CFI11_17525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_17545	COG0251	oxidation-reduction process
CFI11_17555	COG1129	ABC transporter
CFI11_17585	COG1024	Enoyl-CoA hydratase
CFI11_17595	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_17620	COG1796	DNA polymerase
CFI11_17620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CFI11_17625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFI11_17655	COG2070	2-Nitropropane dioxygenase
CFI11_17695	COG0784	Response regulator, receiver
CFI11_17695	COG4191	Histidine kinase
CFI11_17705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFI11_17720	COG2022	thiamine diphosphate biosynthetic process
CFI11_17730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFI11_17735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFI11_17760	COG0410	ABC transporter
CFI11_17785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFI11_17790	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFI11_17795	COG0124	histidyl-tRNA synthetase
CFI11_17800	COG1024	Enoyl-CoA hydratase
CFI11_17815	COG0587	DNA-directed DNA polymerase activity
CFI11_17825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFI11_17855	COG0517	IMP dehydrogenase activity
CFI11_17860	COG0667	Aldo Keto reductase
CFI11_17880	COG0277	FAD linked oxidase domain protein
CFI11_17885	COG0405	Gamma-glutamyltransferase
CFI11_17900	COG0596	Alpha beta hydrolase
CFI11_17905	COG0604	alcohol dehydrogenase
CFI11_17920	COG0789	Transcriptional regulator
CFI11_17940	COG1864	DNA RNA non-specific endonuclease
CFI11_17940	COG3591	Belongs to the peptidase S1B family
CFI11_17945	COG2207	Transcriptional regulator
CFI11_17945	COG1917	Cupin 2, conserved barrel domain protein
CFI11_17955	COG3842	ATPase activity
CFI11_17960	COG0395	ABC-type sugar transport system, permease component
CFI11_17970	COG1653	transport
CFI11_17975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_17980	COG1116	anion transmembrane transporter activity
CFI11_17990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_17995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_18000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFI11_18005	COG0028	Belongs to the TPP enzyme family
CFI11_18010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFI11_18015	COG2855	membrane
CFI11_18020	COG0243	molybdopterin cofactor binding
CFI11_18030	COG0437	4 iron, 4 sulfur cluster binding
CFI11_18040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFI11_18045	COG0741	lytic transglycosylase activity
CFI11_18055	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFI11_18055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_18065	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFI11_18080	COG2885	chlorophyll binding
CFI11_18085	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_18090	COG2169	Transcriptional regulator
CFI11_18090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFI11_18095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFI11_18100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFI11_18110	COG1051	belongs to the nudix hydrolase family
CFI11_18115	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFI11_18115	COG1902	pentaerythritol trinitrate reductase activity
CFI11_18150	COG0583	DNA-binding transcription factor activity
CFI11_18170	COG1058	Belongs to the CinA family
CFI11_18170	COG1546	Belongs to the CinA family
CFI11_18175	COG1489	DNA binding
CFI11_18180	COG0024	Methionine aminopeptidase
CFI11_18190	COG0742	ribosomal rna small subunit methyltransferase
CFI11_18200	COG0678	peroxiredoxin activity
CFI11_18205	COG3920	Histidine kinase
CFI11_18210	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFI11_18230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFI11_18235	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFI11_18240	COG2853	Lipoprotein
CFI11_18260	COG0004	ammonium transporteR
CFI11_18270	COG2897	thiosulfate sulfurtransferase activity
CFI11_18280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFI11_18370	COG3591	Belongs to the peptidase S1B family
CFI11_18375	COG0247	lactate metabolic process
CFI11_18385	COG0277	FAD linked oxidase domain protein
CFI11_18390	COG0277	FAD linked oxidase domain protein
CFI11_18400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFI11_18405	COG0799	negative regulation of ribosome biogenesis
CFI11_18415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFI11_18415	COG3264	Mechanosensitive ion channel
CFI11_18440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFI11_18445	COG0066	3-isopropylmalate dehydratase activity
CFI11_18470	COG0473	3-isopropylmalate dehydrogenase activity
CFI11_18490	COG3008	intermembrane lipid transfer
CFI11_18490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFI11_18495	COG2995	paraquat-inducible protein a
CFI11_18510	COG2188	Transcriptional regulator
CFI11_18515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_18530	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFI11_18545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFI11_18550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFI11_18575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFI11_18585	COG0456	acetyltransferase
CFI11_18585	COG0454	-acetyltransferase
CFI11_18595	COG5328	Belongs to the UPF0262 family
CFI11_18615	COG1959	2 iron, 2 sulfur cluster binding
CFI11_18620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFI11_18650	COG1404	Belongs to the peptidase S8 family
CFI11_18675	COG1414	Transcriptional regulator
CFI11_18730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFI11_18740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFI11_18745	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFI11_18750	COG4133	protoheme IX ABC transporter activity
CFI11_18755	COG3737	Protein of unknown function (DUF498/DUF598)
CFI11_18760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFI11_18765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFI11_18780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFI11_18795	COG3239	Fatty acid desaturase
CFI11_18800	COG1160	GTP binding
CFI11_18820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_18825	COG5265	(ABC) transporter
CFI11_18850	COG1408	metallophosphoesterase
CFI11_18870	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFI11_18870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_18895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_18900	COG4235	cytochrome complex assembly
CFI11_18905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFI11_18920	COG0730	response to heat
CFI11_18925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFI11_18955	COG0745	RESPONSE REGULATOR receiver
CFI11_18965	COG3038	cytochrome b561
CFI11_19025	COG0501	Belongs to the peptidase M48B family
CFI11_19060	COG2204	response regulator
CFI11_19100	COG1295	ribonuclease BN
CFI11_19180	COG4638	Rieske (2fe-2S)
CFI11_19190	COG4176	ABC-type proline glycine betaine transport system permease component
CFI11_19195	COG4175	Glycine betaine
CFI11_19205	COG1309	transcriptional regulator
CFI11_19215	COG4974	Belongs to the 'phage' integrase family
CFI11_19225	COG0717	Belongs to the dCTP deaminase family
CFI11_19320	COG1280	lysine exporter protein (LysE YggA)
CFI11_19330	COG0583	DNA-binding transcription factor activity
CFI11_19350	COG2814	Major facilitator Superfamily
CFI11_19370	COG0477	Major facilitator Superfamily
CFI11_19375	COG1959	2 iron, 2 sulfur cluster binding
CFI11_19395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_19410	COG0633	Ferredoxin
CFI11_19445	COG0737	Belongs to the 5'-nucleotidase family
CFI11_19495	COG0569	domain protein
CFI11_19500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFI11_19505	COG0668	transmembrane transport
CFI11_19545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFI11_19570	COG4789	Type iii secretion
CFI11_19615	COG1450	Type ii and iii secretion system protein
CFI11_19620	COG4792	protein secretion
CFI11_19630	COG4794	Type iii secretion
CFI11_19635	COG4790	Type iii secretion
CFI11_19640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFI11_19650	COG1157	protein secretion by the type III secretion system
CFI11_19685	COG0745	RESPONSE REGULATOR receiver
CFI11_19695	COG2169	Transcriptional regulator
CFI11_19695	COG1917	Cupin 2, conserved barrel domain protein
CFI11_19705	COG2814	Major facilitator Superfamily
CFI11_19715	COG0583	DNA-binding transcription factor activity
CFI11_19755	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CFI11_19760	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CFI11_19765	COG0714	Associated with various cellular activities
CFI11_19770	COG3831	ATPase activity
CFI11_19795	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CFI11_19800	COG0028	Belongs to the TPP enzyme family
CFI11_19805	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_19815	COG2267	carboxylic ester hydrolase activity
CFI11_19830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_19855	COG1414	Transcriptional regulator
CFI11_19880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFI11_19885	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_19905	COG4585	Histidine kinase
CFI11_19910	COG2197	response regulator
CFI11_19925	COG0642	Histidine kinase
CFI11_19930	COG0745	RESPONSE REGULATOR receiver
CFI11_19960	COG4264	IucA IucC family
CFI11_19980	COG0251	oxidation-reduction process
CFI11_20010	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_20030	COG2133	pyrroloquinoline quinone binding
CFI11_20035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_20040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFI11_20045	COG4172	Belongs to the ABC transporter superfamily
CFI11_20050	COG4239	(ABC) transporter, permease
CFI11_20055	COG4174	ABC transporter (Permease)
CFI11_20060	COG4166	transmembrane transport
CFI11_20065	COG3474	cytochrome
CFI11_20080	COG2816	NAD+ diphosphatase activity
CFI11_20085	COG0737	Belongs to the 5'-nucleotidase family
CFI11_20105	COG1309	transcriptional regulator
CFI11_20125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFI11_20135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFI11_20145	COG1335	isochorismatase
CFI11_20150	COG0583	DNA-binding transcription factor activity
CFI11_20185	COG1063	alcohol dehydrogenase
CFI11_20200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFI11_20205	COG0154	amidase activity
CFI11_20210	COG2207	Transcriptional regulator
CFI11_20220	COG1522	sequence-specific DNA binding
CFI11_20225	COG0686	Belongs to the AlaDH PNT family
CFI11_20230	COG1970	mechanosensitive ion channel activity
CFI11_20235	COG0625	glutathione transferase activity
CFI11_20245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFI11_20245	COG0072	phenylalanine-tRNA ligase activity
CFI11_20265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFI11_20295	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFI11_20300	COG0746	molybdenum cofactor guanylyltransferase activity
CFI11_20340	COG1960	acyl-CoA dehydrogenase activity
CFI11_20345	COG0009	L-threonylcarbamoyladenylate synthase
CFI11_20350	COG1678	Uncharacterized ACR, COG1678
CFI11_20375	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFI11_20380	COG1280	lysine exporter protein (LysE YggA)
CFI11_20385	COG1573	uracil-dna glycosylase
CFI11_20390	COG0540	Belongs to the ATCase OTCase family
CFI11_20410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFI11_20415	COG1505	serine-type exopeptidase activity
CFI11_20450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFI11_20470	COG0314	molybdopterin synthase activity
CFI11_20480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFI11_20485	COG0322	excinuclease ABC activity
CFI11_20490	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_20500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFI11_20500	COG0616	signal peptide processing
CFI11_20505	COG0842	Transport permease protein
CFI11_20510	COG1131	(ABC) transporter
CFI11_20515	COG0697	spore germination
CFI11_20520	COG1024	Enoyl-CoA hydratase
CFI11_20535	COG4977	sequence-specific DNA binding
CFI11_20535	COG1917	Cupin 2, conserved barrel domain protein
CFI11_20550	COG0339	signal peptide processing
CFI11_20555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFI11_20560	COG0756	dUTP diphosphatase activity
CFI11_20565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFI11_20575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFI11_20595	COG0606	chelatase, subunit chli
CFI11_20610	COG0792	nuclease activity
CFI11_20615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFI11_20625	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFI11_20640	COG0180	Tryptophanyl-tRNA synthetase
CFI11_20665	COG0018	arginyl-trna synthetase
CFI11_20670	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFI11_20705	COG0730	response to heat
CFI11_20715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFI11_20755	COG0813	purine-nucleoside phosphorylase activity
CFI11_20810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_20820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_20825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFI11_20830	COG0277	FAD linked oxidase domain protein
CFI11_20830	COG0247	lactate metabolic process
CFI11_20835	COG1802	Transcriptional regulator
CFI11_20870	COG3501	Rhs element vgr protein
CFI11_20890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_20895	COG1120	ATPase activity
CFI11_20900	COG1309	transcriptional regulator
CFI11_20905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFI11_20915	COG0625	glutathione transferase activity
CFI11_20945	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFI11_20950	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CFI11_20970	COG2211	Major facilitator Superfamily
CFI11_20980	COG1024	Enoyl-CoA hydratase
CFI11_20990	COG2080	2 iron, 2 sulfur cluster binding
CFI11_21025	COG0747	negative chemotaxis
CFI11_21045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_21075	COG1595	DNA-templated transcription, initiation
CFI11_21120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFI11_21125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFI11_21130	COG0069	glutamate synthase activity
CFI11_21140	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFI11_21145	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFI11_21165	COG0284	orotidine-5'-phosphate decarboxylase activity
CFI11_21190	COG4191	Histidine kinase
CFI11_21195	COG0745	RESPONSE REGULATOR receiver
CFI11_21210	COG3383	formate dehydrogenase (NAD+) activity
CFI11_21220	COG0625	glutathione transferase activity
CFI11_21235	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_21260	COG1595	DNA-templated transcription, initiation
CFI11_21265	COG3806	Anti-sigma factor
CFI11_21280	COG1322	Protein conserved in bacteria
CFI11_21285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFI11_21295	COG1294	oxidase, subunit
CFI11_21300	COG1271	oxidase subunit
CFI11_21310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_21320	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFI11_21325	COG3257	ureidoglycine aminohydrolase activity
CFI11_21335	COG2351	hydroxyisourate hydrolase activity
CFI11_21340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFI11_21345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFI11_21345	COG1321	iron dependent repressor
CFI11_21350	COG1121	(ABC) transporter
CFI11_21355	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFI11_21360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFI11_21365	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_21375	COG0612	Peptidase, M16
CFI11_21380	COG0612	Peptidase, M16
CFI11_21390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFI11_21405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFI11_21405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFI11_21420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFI11_21425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFI11_21430	COG3698	Phosphodiester glycosidase
CFI11_21435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFI11_21450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFI11_21460	COG1185	polyribonucleotide nucleotidyltransferase activity
CFI11_21470	COG0450	alkyl hydroperoxide reductase
CFI11_21485	COG0564	pseudouridine synthase activity
CFI11_21515	COG1280	lysine exporter protein (LysE YggA)
CFI11_21535	COG1366	Belongs to the anti-sigma-factor antagonist family
CFI11_21545	COG0405	Gamma-glutamyltransferase
CFI11_21570	COG1674	ftsk spoiiie
CFI11_21575	COG0436	Aminotransferase
CFI11_21580	COG0154	amidase activity
CFI11_21585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFI11_21590	COG2835	tetraacyldisaccharide 4'-kinase activity
CFI11_21605	COG0708	Exodeoxyribonuclease III
CFI11_21620	COG0745	RESPONSE REGULATOR receiver
CFI11_21640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFI11_21660	COG0495	leucyl-tRNA aminoacylation
CFI11_21675	COG0625	glutathione transferase activity
CFI11_21680	COG2081	HI0933 family
CFI11_21705	COG0312	modulator of DNA gyrase
CFI11_21725	COG1663	tetraacyldisaccharide 4'-kinase activity
CFI11_21735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFI11_21735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFI11_21745	COG1194	a g-specific adenine glycosylase
CFI11_21780	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFI11_21785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFI11_21790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_21800	COG3046	protein related to deoxyribodipyrimidine photolyase
CFI11_21815	COG0583	DNA-binding transcription factor activity
CFI11_21965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFI11_21975	COG1609	Transcriptional regulator
CFI11_21980	COG3214	Protein conserved in bacteria
CFI11_21990	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFI11_22025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFI11_22045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_22100	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_22130	COG2226	methyltransferase
CFI11_22145	COG3842	ATPase activity
CFI11_22155	COG1175	transmembrane transport
CFI11_22160	COG3833	ABC-type maltose transport systems, permease component
CFI11_22180	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_22215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_22235	COG0589	response to stress
CFI11_22250	COG3976	FMN-binding domain protein
CFI11_22250	COG1053	succinate dehydrogenase
CFI11_22300	COG0028	Belongs to the TPP enzyme family
CFI11_22320	COG3220	belongs to the UPF0276 family
CFI11_22360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CFI11_22365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFI11_22375	COG0028	Belongs to the TPP enzyme family
CFI11_22420	COG0747	negative chemotaxis
CFI11_22430	COG0601	transmembrane transport
CFI11_22440	COG0444	Belongs to the ABC transporter superfamily
CFI11_22445	COG4608	Belongs to the ABC transporter superfamily
CFI11_22450	COG4166	transmembrane transport
CFI11_22455	COG0601	transmembrane transport
CFI11_22460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_22460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_22465	COG4172	Belongs to the ABC transporter superfamily
CFI11_22470	COG1129	ABC transporter
CFI11_22495	COG0583	DNA-binding transcription factor activity
CFI11_22505	COG0489	protein tyrosine kinase activity
CFI11_22510	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFI11_22515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_22520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_22525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFI11_22555	COG3119	arylsulfatase activity
CFI11_22570	COG0583	DNA-binding transcription factor activity
CFI11_22595	COG5002	protein histidine kinase activity
CFI11_22600	COG1858	cytochrome C peroxidase
CFI11_22610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFI11_22615	COG0583	DNA-binding transcription factor activity
CFI11_22655	COG3501	Rhs element vgr protein
CFI11_22720	COG0628	permease
CFI11_22760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFI11_22765	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFI11_22780	COG2264	protein methyltransferase activity
CFI11_22795	COG0438	transferase activity, transferring glycosyl groups
CFI11_22810	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_22815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_22830	COG1802	Transcriptional regulator
CFI11_22840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFI11_22845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFI11_22850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_22870	COG0625	glutathione transferase activity
CFI11_22875	COG2808	Putative FMN-binding domain
CFI11_22885	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFI11_22895	COG4143	(ABC) transporter
CFI11_22900	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFI11_22905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFI11_22930	COG2171	N-acyltransferase activity
CFI11_22950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFI11_22955	COG0557	exoribonuclease II activity
CFI11_22975	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CFI11_23010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFI11_23020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFI11_23050	COG1968	undecaprenyl-diphosphatase activity
CFI11_23075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFI11_23080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFI11_23080	COG0517	IMP dehydrogenase activity
CFI11_23095	COG1137	ATPase activity
CFI11_23100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFI11_23105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFI11_23130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFI11_23145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFI11_23150	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFI11_23165	COG3145	DNA-N1-methyladenine dioxygenase activity
CFI11_23175	COG0443	Heat shock 70 kDa protein
CFI11_23180	COG0484	heat shock protein binding
CFI11_23190	COG2003	Belongs to the UPF0758 family
CFI11_23195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFI11_23205	COG0653	protein targeting
CFI11_23210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFI11_23215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFI11_23220	COG0494	nUDIX hydrolase
CFI11_23230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFI11_23245	COG0779	Required for maturation of 30S ribosomal subunits
CFI11_23260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFI11_23270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFI11_23275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFI11_23285	COG2226	methyltransferase
CFI11_23310	COG3034	peptidoglycan biosynthetic process
CFI11_23320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFI11_23325	COG1132	(ABC) transporter
CFI11_23330	COG1132	(ABC) transporter
CFI11_23340	COG0494	nUDIX hydrolase
CFI11_23345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFI11_23350	COG0494	nUDIX hydrolase
CFI11_23355	COG0745	RESPONSE REGULATOR receiver
CFI11_23370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFI11_23380	COG0137	argininosuccinate synthase activity
CFI11_23400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFI11_23405	COG1105	Belongs to the carbohydrate kinase PfkB family
CFI11_23410	COG0281	malic enzyme
CFI11_23410	COG0280	phosphate acetyltransferase
CFI11_23415	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFI11_23420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFI11_23425	COG1420	regulation of RNA biosynthetic process
CFI11_23430	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFI11_23435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFI11_23440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFI11_23445	COG1475	DNA binding
CFI11_23450	COG1192	Involved in chromosome partitioning
CFI11_23455	COG0357	Ribosomal RNA small subunit methyltransferase G
CFI11_23460	COG0445	tRNA wobble uridine modification
CFI11_23465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFI11_23470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFI11_23480	COG1192	Involved in chromosome partitioning
CFI11_23485	COG1475	DNA binding
CFI11_23495	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CFI11_23500	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CFI11_23510	COG1233	COG1233 Phytoene dehydrogenase and related
CFI11_23515	COG1562	ergosterol biosynthetic process
CFI11_23520	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CFI11_23525	COG5621	secreted hydrolase
CFI11_23530	COG1233	COG1233 Phytoene dehydrogenase and related
CFI11_23535	COG0142	geranyltranstransferase activity
CFI11_23540	COG0500	methyltransferase
CFI11_23550	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CFI11_23555	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_23560	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_23595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFI11_23600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFI11_23605	COG3191	aminopeptidase activity
CFI11_23610	COG0662	Cupin 2, conserved barrel domain protein
CFI11_23645	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFI11_23650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFI11_23655	COG1230	cation diffusion facilitator family transporter
CFI11_23665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFI11_23670	COG2211	Major facilitator Superfamily
CFI11_23675	COG0644	oxidoreductase
CFI11_23680	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CFI11_23690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_23720	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFI11_23735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFI11_23745	COG3842	ATPase activity
CFI11_23760	COG0395	ABC-type sugar transport system, permease component
CFI11_23780	COG1063	alcohol dehydrogenase
CFI11_23785	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_23790	COG2084	Dehydrogenase
CFI11_23800	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_23805	COG2188	Transcriptional regulator
CFI11_23815	COG0747	negative chemotaxis
CFI11_23840	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_23845	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_23850	COG1429	ligase activity, forming nitrogen-metal bonds
CFI11_23855	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CFI11_23870	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CFI11_23890	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CFI11_23900	COG0156	8-amino-7-oxononanoate synthase activity
CFI11_23905	COG3474	cytochrome
CFI11_23910	COG0457	Tetratricopeptide repeat
CFI11_23915	COG1487	ribonuclease activity
CFI11_23940	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CFI11_23945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_23955	COG1216	Glycosyl transferase, family 2
CFI11_23970	COG1216	Glycosyl transferase, family 2
CFI11_24035	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFI11_24145	COG1192	Involved in chromosome partitioning
CFI11_24150	COG1192	Involved in chromosome partitioning
CFI11_24165	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_24170	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFI11_24185	COG1609	Transcriptional regulator
CFI11_24190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_24195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_24210	COG3395	kinase activity
CFI11_24215	COG0235	Class ii aldolase
CFI11_24220	COG3622	Belongs to the hyi family
CFI11_24235	COG0747	negative chemotaxis
CFI11_24240	COG0601	transmembrane transport
CFI11_24245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_24250	COG0444	Belongs to the ABC transporter superfamily
CFI11_24255	COG4608	Belongs to the ABC transporter superfamily
CFI11_24270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFI11_24275	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFI11_24280	COG0129	dihydroxy-acid dehydratase activity
CFI11_24285	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_24295	COG1802	Transcriptional regulator
CFI11_24315	COG2721	sulfolactate sulfo-lyase activity
CFI11_24320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFI11_24330	COG0697	spore germination
CFI11_24335	COG0246	Mannitol dehydrogenase
CFI11_24340	COG1904	glucuronate isomerase
CFI11_24355	COG0673	inositol 2-dehydrogenase activity
CFI11_24360	COG1312	Catalyzes the dehydration of D-mannonate
CFI11_24415	COG0583	DNA-binding transcription factor activity